Jean-Philippe Nougayrede

PhD

Toulouse | France

Jean-Philippe Nougayrede

PhD
Introduction
Metrics

37

Publications

395

Profile Views

201

Reads

1005

PubMed Central Citations

Publications

37Publications

201Reads

1005PubMed Central Citations

The Enterobacterial Genotoxins: Cytolethal Distending Toxin and Colibactin.

EcoSal Plus 2016 07;7(1)

Institut de Recherche en Santé Digestive (IRSD), INRA UMR1416, INSERM U1220, Université de Toulouse, CHU Purpan, Toulouse, FRANCE.

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July 2016
1 Read
5 PubMed Central Citations(source)

Escherichia coli ClbS is a colibactin resistance protein.

Mol Microbiol 2016 Mar 1;99(5):897-908. Epub 2015 Dec 1.

INRA, USC 1360, Toulouse, France.

View Article
March 2016
6 Reads
4.42 Impact Factor

HlyF Produced by Extraintestinal Pathogenic Escherichia coli Is a Virulence Factor That Regulates Outer Membrane Vesicle Biogenesis.

J Infect Dis 2016 Mar 22;213(5):856-65. Epub 2015 Oct 22.

INSERM, UMR1043 INRA, USC 1360 CNRS, UMR5282 Université de Toulouse, UPS, Centre de Physiopathologie de Toulouse Purpan CHU Toulouse, Hôpital Purpan, Service de bactériologie-hygiène.

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March 2016
5 Reads
2 PubMed Central Citations(source)
6.00 Impact Factor

Maternally acquired genotoxic Escherichia coli alters offspring's intestinal homeostasis.

Gut Microbes 2014 May-Jun;5(3):313-25. Epub 2014 Jun 27.

INRA; USC 1360; Toulouse, France; Inserm; UMR1043; Toulouse, France; CNRS; UMR5282; Toulouse, France; Université de Toulouse; UPS; Toulouse, France; CHU Toulouse; Hôpital Purpan; Service de bactériologie-Hygiène; Toulouse, France.

View Article
May 2015
4 Reads
7 PubMed Central Citations(source)

The genotoxin colibactin exacerbates lymphopenia and decreases survival rate in mice infected with septicemic Escherichia coli.

J Infect Dis 2014 Jul 31;210(2):285-94. Epub 2014 Jan 31.

UMR1043, Inserm USC 1360, INRA UMR 5282, CNRS UPS, Centre de Physiopathologie de Toulouse Purpan, UPS, Université de Toulouse Hôpital Purpan, Service de bactériologie-Hygiène, CHU Toulouse, Toulouse.

View Article
July 2014
17 Reads
9 PubMed Central Citations(source)
6.00 Impact Factor

Escherichia coli producing colibactin triggers premature and transmissible senescence in mammalian cells.

PLoS One 2013 8;8(10):e77157. Epub 2013 Oct 8.

INRA, USC 1360, Toulouse, France ; INSERM, UMR 1043, Toulouse, France ; CNRS, UMR 5282, Toulouse, France ; Université de Toulouse, UPS, Centre de Physiopathologie Toulouse Purpan (CPTP), Toulouse, France.

View Article
June 2014
7 Reads
19 PubMed Central Citations(source)
3.23 Impact Factor

The carbon storage regulator (Csr) system exerts a nutrient-specific control over central metabolism in Escherichia coli strain Nissle 1917.

PLoS One 2013 20;8(6):e66386. Epub 2013 Jun 20.

Laboratoire d'Ingénierie des Systèmes Biologiques et des Procédés, LISBP, Université de Toulouse, INSA, UPS, INP, Toulouse, France.

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February 2014
15 Reads
9 PubMed Central Citations(source)
3.23 Impact Factor

In vitro evolution of an archetypal enteropathogenic Escherichia coli strain.

J Bacteriol 2013 Oct 2;195(19):4476-83. Epub 2013 Aug 2.

Department of Medicine.

View Article
October 2013
1 Read
5 PubMed Central Citations(source)
2.81 Impact Factor

ClbP is a prototype of a peptidase subgroup involved in biosynthesis of nonribosomal peptides.

J Biol Chem 2011 Oct 27;286(41):35562-70. Epub 2011 Jul 27.

Laboratoire de Bactériologie Clinique, Centre Hospitalier de Clermont-Ferrand, Clermont-Ferrand F-63003, France.

View Article
October 2011
7 Reads
15 PubMed Central Citations(source)
4.57 Impact Factor

[Microbiota and colorectal cancer: genotoxic bacteria in the intestinal tract].

Bull Acad Natl Med 2011 Jun;195(6):1295-304; discussion 1304-5

Pathogénie moléculaire et cellulaire des infections à Escherichia coil, INRA USC--INSERM U1043, F-31000 Toulouse, France.

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June 2011
1 Read
2 PubMed Central Citations(source)
0.22 Impact Factor

Cycle inhibiting factors (cifs): cyclomodulins that usurp the ubiquitin-dependent degradation pathway of host cells.

Toxins (Basel) 2011 04 29;3(4):356-68. Epub 2011 Mar 29.

INRA, USC Molecular and Cellular Pathogenesis of Escherichia coli Infections, Toulouse, F-31300, France.

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April 2011
5 Reads
10 PubMed Central Citations(source)
2.48 Impact Factor

Deoxynivalenol impairs porcine intestinal barrier function and decreases the protein expression of claudin-4 through a mitogen-activated protein kinase-dependent mechanism.

J Nutr 2010 Nov 22;140(11):1956-62. Epub 2010 Sep 22.

Laboratoire de Pharmacologie et Toxicologie UR66, INRA, F-31931 Toulouse, France.

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November 2010
1 Read
27 PubMed Central Citations(source)
3.88 Impact Factor

Escherichia coli induces DNA damage in vivo and triggers genomic instability in mammalian cells.

Proc Natl Acad Sci U S A 2010 Jun 7;107(25):11537-42. Epub 2010 Jun 7.

Institut National de la Recherche Agronomique, Unité Mixte de Recherche 1225, F-31076 Toulouse, France.

View Article
June 2010
5 Reads
105 PubMed Central Citations(source)
9.81 Impact Factor

The enteropathogenic Escherichia coli effector Cif induces delayed apoptosis in epithelial cells.

Infect Immun 2009 Dec 28;77(12):5471-7. Epub 2009 Sep 28.

Université de Toulouse, ENVT, UMR 1225, F-31076 Toulouse, France.

View Article
December 2009
3 Reads
16 PubMed Central Citations(source)
3.73 Impact Factor

Genetic structure and distribution of the colibactin genomic island among members of the family Enterobacteriaceae.

Infect Immun 2009 Nov 31;77(11):4696-703. Epub 2009 Aug 31.

Julius-Maximilians-Universität Würzburg, Institut für Molekulare Infektionsbiologie, Röntgenring 11, D-97070 Würzburg, Germany.

View Article
November 2009
9 Reads
48 PubMed Central Citations(source)
3.73 Impact Factor

Cif type III effector protein: a smart hijacker of the host cell cycle.

Future Microbiol 2009 Sep;4(7):867-77

INRA, UMR 1225, Toulouse, France.

View Article
September 2009
3 Reads
8 PubMed Central Citations(source)
4.28 Impact Factor

Cytolethal distending toxin type I and type IV genes are framed with lambdoid prophage genes in extraintestinal pathogenic Escherichia coli.

Infect Immun 2009 Jan 3;77(1):492-500. Epub 2008 Nov 3.

Veterinary Medical Research Institute of the Hungarian Academy of Sciences, Budapest, Hungary.

View Article
January 2009
7 Reads
17 PubMed Central Citations(source)
3.73 Impact Factor

Molecular epidemiology and phylogenetic distribution of the Escherichia coli pks genomic island.

J Clin Microbiol 2008 Dec 22;46(12):3906-11. Epub 2008 Oct 22.

Medical Service, Veterans Affairs Medical Center, Minneapolis, Minnesota 55417, USA.

View Article
December 2008
3 Reads
35 PubMed Central Citations(source)
3.99 Impact Factor

Bacterial cyclomodulin Cif blocks the host cell cycle by stabilizing the cyclin-dependent kinase inhibitors p21 and p27.

Cell Microbiol 2008 Dec 13;10(12):2496-508. Epub 2008 Aug 13.

INRA, UMR 1225, F-31076 Toulouse, France.

View Article
December 2008
7 Reads
25 PubMed Central Citations(source)
4.92 Impact Factor

Structure of the cyclomodulin Cif from pathogenic Escherichia coli.

J Mol Biol 2008 Dec 27;384(2):465-77. Epub 2008 Sep 27.

Laboratory of Structural Microbiology, Rockefeller University, New York, NY 10021, USA.

View Article
December 2008
3 Reads
24 PubMed Central Citations(source)
4.33 Impact Factor

EspF Interacts with nucleation-promoting factors to recruit junctional proteins into pedestals for pedestal maturation and disruption of paracellular permeability.

Infect Immun 2008 Sep 16;76(9):3854-68. Epub 2008 Jun 16.

Departments of Cell Biology, Centro de Investigación y de Estudios Avanzados, CINVESTAV-IPN, Mexico DF, Mexico.

View Article
September 2008
3 Reads
14 PubMed Central Citations(source)
3.73 Impact Factor

Enteropathogenic Escherichia coli effector EspF interacts with host protein Abcf2.

Cell Microbiol 2007 Mar 25;9(3):680-93. Epub 2006 Oct 25.

University of Maryland Baltimore, School of Medicine, Division of Infectious Diseases, 20 Penn Street, Baltimore, MD 21201, USA.

View Article
March 2007
2 Reads
20 PubMed Central Citations(source)
4.92 Impact Factor

Escherichia coli cyclomodulin Cif induces G2 arrest of the host cell cycle without activation of the DNA-damage checkpoint-signalling pathway.

Cell Microbiol 2006 Dec 11;8(12):1910-21. Epub 2006 Jul 11.

UMR 1225, IHAP, INRA-ENVT, 23 Chemin des Capelles, BP 87614, 31000 Toulouse, France.

View Article
December 2006
7 Reads
27 PubMed Central Citations(source)
4.92 Impact Factor

Escherichia coli induces DNA double-strand breaks in eukaryotic cells.

Science 2006 Aug;313(5788):848-51

INRA, UMR1225, Ecole Nationale Vétérinaire de Toulouse, Toulouse F-31076, France.

View Article
August 2006
10 Reads
143 PubMed Central Citations(source)
31.48 Impact Factor

Cyclomodulins: bacterial effectors that modulate the eukaryotic cell cycle.

Trends Microbiol 2005 Mar;13(3):103-10

UMR 1225 Interactions Hôtes-Agents Pathogènes, Ecole Nationale Vétérinaire, 23 chemin des Capelles BP 87614 31076, Toulouse Cedex 3, France.

View Article
March 2005
2 Reads
71 PubMed Central Citations(source)
9.19 Impact Factor

Bacterial toxins that modulate host cell-cycle progression.

Curr Opin Microbiol 2005 Feb;8(1):83-91

UMR1225 "Interactions Hôtes-Agents Pathogènes", Ecole Nationale Vétérinaire, 23 chemin des Capelles, 31076 Toulouse, France.

View Article
February 2005
9 Reads
57 PubMed Central Citations(source)
5.90 Impact Factor

Enteropathogenic Escherichia coli EspF is targeted to mitochondria and is required to initiate the mitochondrial death pathway.

Cell Microbiol 2004 Nov;6(11):1097-111

University of Maryland, Baltimore School of Medicine, Division of Infectious Diseases, 10 S. Pine Street, MSTF 900, Baltimore, MD 21201, USA.

View Article
November 2004
13 Reads
51 PubMed Central Citations(source)
4.92 Impact Factor

Genetically engineered enteropathogenic Escherichia coli strain elicits a specific immune response and protects against a virulent challenge.

Microbes Infect 2003 Aug;5(10):857-67

UMR 1225, Institut National de la Recherche Agronomique, Ecole Nationale Vétérinaire de Toulouse, 31076 Toulouse cedex 3, France.

View Article
August 2003
3 Reads
6 PubMed Central Citations(source)
2.86 Impact Factor

Adhesion of enteropathogenic Escherichia coli to host cells.

Cell Microbiol 2003 Jun;5(6):359-72

Division of Infectious Diseases, University of Maryland, Baltimore, 10 S Pine Street, Baltimore, MD 21201, USA.

View Article
June 2003
56 PubMed Central Citations(source)
4.92 Impact Factor