Jean-Paul Achkar

Jean-Paul Achkar

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Jean-Paul Achkar

Jean-Paul Achkar

Publications by authors named "Jean-Paul Achkar"

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Jejunal necrosis after internal herniation of Roux limb through Petersen defect.

Gastrointest Endosc 2019 08 5;90(2):317-318. Epub 2019 Apr 5.

Department of Gastroenterology and Hepatology, Digestive Disease and Surgical Institute, Cleveland Clinic Foundation, Cleveland, Ohio, USA.

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http://dx.doi.org/10.1016/j.gie.2019.04.198DOI Listing
August 2019

Tailored Medical Management of the Complex Postoperative Crohn's Disease Patient.

Authors:
Jean-Paul Achkar

Clin Colon Rectal Surg 2019 Jul 2;32(4):225-230. Epub 2019 Jul 2.

Kenneth Rainin Endowed Chair for IBD Research, Department of Gastroenterology and Hepatology, Cleveland Clinic, Cleveland, Ohio.

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http://dx.doi.org/10.1055/s-0039-1683853DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6606319PMC
July 2019

Underutilization of Combination Anti-TNF Therapy in Population-based Study.

Inflamm Bowel Dis 2019 Jul 24. Epub 2019 Jul 24.

Department of Gastroenterology, Hepatology, and Nutrition, Cleveland Clinic, Cleveland, Ohio.

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http://dx.doi.org/10.1093/ibd/izz150DOI Listing
July 2019

Acupuncture in Inflammatory Bowel Disease.

Inflamm Bowel Dis 2019 06;25(7):1129-1139

Department of Gastroenterology, Hepatology & Nutrition, Department of Inflammation and Immunity, Cleveland Clinic, Cleveland, Ohio.

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http://dx.doi.org/10.1093/ibd/izy371DOI Listing
June 2019

Impact of Low Immunoglobulin G Levels on Disease Outcomes in Patients with Inflammatory Bowel Diseases.

Dig Dis Sci 2016 11 12;61(11):3270-3277. Epub 2016 Sep 12.

Center for Inflammatory Bowel Diseases, Digestive Disease and Surgery Institute-A31, The Cleveland Clinic Foundation, 9500 Euclid Ave., Cleveland, OH, 44195, USA.

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http://dx.doi.org/10.1007/s10620-016-4294-zDOI Listing
November 2016

The Significance of Sessile Serrated Polyps in Inflammatory Bowel Disease.

Inflamm Bowel Dis 2016 09;22(9):2213-20

*Digestive Disease Institute, Cleveland Clinic, Cleveland, Ohio; †Section of Gastroenterology, Department of Veterans Affairs, Louis Stokes Cleveland Medical Center, Cleveland, Ohio; ‡Department of Pathology and Laboratory Medicine, North Shore-Long Island Jewish Health System, New Hyde Park, New York; §Robert J. Tomsich Pathology and Laboratory Medicine Institute, Cleveland Clinic, Cleveland, Ohio; ‖Department of Laboratory Medicine and Pathology, Mayo Clinic, Scottsdale, Arizona; and ¶Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio.

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http://dx.doi.org/10.1097/MIB.0000000000000895DOI Listing
September 2016

Gene-environment interactions in inflammatory bowel disease pathogenesis.

Curr Opin Gastroenterol 2015 Jul;31(4):277-82

aDepartment of Gastroenterology and Hepatology, Digestive Disease Institute, Cleveland Clinic bDepartment of Pathobiology, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA.

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http://dx.doi.org/10.1097/MOG.0000000000000188DOI Listing
July 2015

Conventional risk factors and cardiovascular outcomes of patients with inflammatory bowel disease with confirmed coronary artery disease.

Inflamm Bowel Dis 2015 Jan;21(1):E2

*Department of Internal Medicine, Medicine Institute, Cleveland Clinic †Department of Gastroenterology & Hepatology, Digestive Disease Institute, Cleveland Clinic ‡Department of Cardiology, Heart and Vascular Institute, Cleveland Clinic §Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio.

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http://pdfs.journals.lww.com/ibdjournal/2014/09000/Conventio
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http://dx.doi.org/10.1097/MIB.0000000000000275DOI Listing
January 2015

Impact of abdominal visceral adipose tissue on disease outcome in pediatric Crohn's disease.

Inflamm Bowel Dis 2014 Dec;20(12):2286-91

Departments of *Pediatric Gastroenterology, and †Pathobiology, Cleveland Clinic, Cleveland, Ohio; ‡Department of Gastroenterology, Digestive Disease Institute, Cleveland Clinic, Cleveland, Ohio; §Department of Radiology, Children's Hospital and Research Center of Oakland, Oakland, California; and ‖Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio.

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http://dx.doi.org/10.1097/MIB.0000000000000200DOI Listing
December 2014

Conventional risk factors and cardiovascular outcomes of patients with inflammatory bowel disease with confirmed coronary artery disease.

Inflamm Bowel Dis 2014 Sep;20(9):1593-601

*Department of Internal Medicine, Medicine Institute, Cleveland Clinic, Cleveland, OH; †Department of Gastroenterology and Hepatology, Digestive Disease Institute, Cleveland Clinic, Cleveland, OH; ‡Department of Cardiology, Heart and Vascular Institute, Cleveland Clinic, Cleveland, OH; and §Department of Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH.

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http://dx.doi.org/10.1097/MIB.0000000000000109DOI Listing
September 2014

Gene-gene and gene-environment interactions in ulcerative colitis.

Hum Genet 2014 May 17;133(5):547-58. Epub 2013 Nov 17.

Department of Gastroenterology and Hepatology, Digestive Disease Institute, Cleveland Clinic, 9500 Euclid Avenue, Desk A31, Cleveland, OH, 44195, USA,

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http://dx.doi.org/10.1007/s00439-013-1395-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064459PMC
May 2014

A novel approach to detect cumulative genetic effects and genetic interactions in Crohn's disease.

Inflamm Bowel Dis 2013 Aug;19(9):1799-808

Department of Gastroenterology and Hepatology, Digestive Disease Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA.

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http://dx.doi.org/10.1097/MIB.0b013e31828706a0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3720692PMC
August 2013

Dense genotyping of immune-related disease regions identifies nine new risk loci for primary sclerosing cholangitis.

Nat Genet 2013 Jun 21;45(6):670-5. Epub 2013 Apr 21.

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge, UK.

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http://petercroucher.com/wp-content/uploads/2013/10/51_Natur
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http://www.nature.com/doifinder/10.1038/ng.2616
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http://dx.doi.org/10.1038/ng.2616DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3667736PMC
June 2013

Host-microbe interactions have shaped the genetic architecture of inflammatory bowel disease.

Authors:
Luke Jostins Stephan Ripke Rinse K Weersma Richard H Duerr Dermot P McGovern Ken Y Hui James C Lee L Philip Schumm Yashoda Sharma Carl A Anderson Jonah Essers Mitja Mitrovic Kaida Ning Isabelle Cleynen Emilie Theatre Sarah L Spain Soumya Raychaudhuri Philippe Goyette Zhi Wei Clara Abraham Jean-Paul Achkar Tariq Ahmad Leila Amininejad Ashwin N Ananthakrishnan Vibeke Andersen Jane M Andrews Leonard Baidoo Tobias Balschun Peter A Bampton Alain Bitton Gabrielle Boucher Stephan Brand Carsten Büning Ariella Cohain Sven Cichon Mauro D'Amato Dirk De Jong Kathy L Devaney Marla Dubinsky Cathryn Edwards David Ellinghaus Lynnette R Ferguson Denis Franchimont Karin Fransen Richard Gearry Michel Georges Christian Gieger Jürgen Glas Talin Haritunians Ailsa Hart Chris Hawkey Matija Hedl Xinli Hu Tom H Karlsen Limas Kupcinskas Subra Kugathasan Anna Latiano Debby Laukens Ian C Lawrance Charlie W Lees Edouard Louis Gillian Mahy John Mansfield Angharad R Morgan Craig Mowat William Newman Orazio Palmieri Cyriel Y Ponsioen Uros Potocnik Natalie J Prescott Miguel Regueiro Jerome I Rotter Richard K Russell Jeremy D Sanderson Miquel Sans Jack Satsangi Stefan Schreiber Lisa A Simms Jurgita Sventoraityte Stephan R Targan Kent D Taylor Mark Tremelling Hein W Verspaget Martine De Vos Cisca Wijmenga David C Wilson Juliane Winkelmann Ramnik J Xavier Sebastian Zeissig Bin Zhang Clarence K Zhang Hongyu Zhao Mark S Silverberg Vito Annese Hakon Hakonarson Steven R Brant Graham Radford-Smith Christopher G Mathew John D Rioux Eric E Schadt Mark J Daly Andre Franke Miles Parkes Severine Vermeire Jeffrey C Barrett Judy H Cho

Nature 2012 Nov;491(7422):119-24

Wellcome Trust Sanger Institute, Wellcome Trust Genome Campus, Hinxton, Cambridge CB10 1HH, UK.

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http://dx.doi.org/10.1038/nature11582DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3491803PMC
November 2012

Efficacy of oral vs. topical, or combined oral and topical 5-aminosalicylates, in Ulcerative Colitis: systematic review and meta-analysis.

Am J Gastroenterol 2012 Feb 22;107(2):167-76; author reply 177. Epub 2011 Nov 22.

Leeds Gastroenterology Institute, Leeds General Infirmary, Leeds, UK.

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http://dx.doi.org/10.1038/ajg.2011.410DOI Listing
February 2012

Pathogenesis of postoperative recurrence in Crohn's disease.

Gut 2011 Apr 29;60(4):553-62. Epub 2010 Nov 29.

Department of Gastroenterology, Digestive Diseases Institute, Cleveland Clinic, Cleveland, Ohio, USA.

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http://dx.doi.org/10.1136/gut.2010.221705DOI Listing
April 2011

Molecular pathways underlying IBD-associated colorectal neoplasia: therapeutic implications.

Am J Gastroenterol 2011 Apr 8;106(4):719-30. Epub 2011 Mar 8.

Department of Internal Medicine, Cleveland Clinic, Cleveland, OH, USA.

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http://www.nature.com/articles/ajg201151
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http://dx.doi.org/10.1038/ajg.2011.51DOI Listing
April 2011

Efficacy of 5-aminosalicylates in ulcerative colitis: systematic review and meta-analysis.

Am J Gastroenterol 2011 Apr 15;106(4):601-16. Epub 2011 Mar 15.

Leeds Gastroenterology Institute, Leeds General Infirmary, Leeds, UK.

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http://www.nature.com/articles/ajg201167
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http://dx.doi.org/10.1038/ajg.2011.67DOI Listing
April 2011

Efficacy of 5-aminosalicylates in Crohn's disease: systematic review and meta-analysis.

Am J Gastroenterol 2011 Apr 15;106(4):617-29. Epub 2011 Mar 15.

Leeds Gastroenterology Institute, Leeds General Infirmary, Leeds, UK.

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http://dx.doi.org/10.1038/ajg.2011.71DOI Listing
April 2011

An evidence-based systematic review on medical therapies for inflammatory bowel disease.

Am J Gastroenterol 2011 Apr;106 Suppl 1:S2-25; quiz S26

Department of Medicine, Faculty of Health, University of Newcastle, Callaghan, NSW 2308, Australia.

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http://www.nature.com/articles/ajg201158
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http://dx.doi.org/10.1038/ajg.2011.58DOI Listing
April 2011

ATG16L1 and NOD2 interact in an autophagy-dependent antibacterial pathway implicated in Crohn's disease pathogenesis.

Gastroenterology 2010 Nov 14;139(5):1630-41, 1641.e1-2. Epub 2010 Jul 14.

Department of Pathobiology, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio 44195, USA.

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http://dx.doi.org/10.1053/j.gastro.2010.07.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2967588PMC
November 2010

Gene-gene interactions in inflammatory bowel disease: biological and clinical implications.

Am J Gastroenterol 2009 Jul 12;104(7):1734-6. Epub 2009 May 12.

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http://dx.doi.org/10.1038/ajg.2009.179DOI Listing
July 2009

Helping patients make informed choices about probiotics: a need for research.

Am J Gastroenterol 2009 Apr;104(4):809-13

Department of Bioethics, Cleveland Clinic, Cleveland, Ohio 44195, USA.

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http://dx.doi.org/10.1038/ajg.2008.68DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2746707PMC
April 2009

Mural attenuation in normal small bowel and active inflammatory Crohn's disease on CT enterography: location, absolute attenuation, relative attenuation, and the effect of wall thickness.

AJR Am J Roentgenol 2009 Feb;192(2):417-23

Imaging Institute, Department of Quantitative Health Sciences and Digestive Disease Institute, Cleveland Clinic, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.2214/AJR.08.1267DOI Listing
February 2009

Long-term outcomes with ileal pouch-anal anastomosis and Crohn's disease: pouch retention and implications of delayed diagnosis.

Ann Surg 2008 Oct;248(4):608-16

Digestive Disease Institute, Department of Colorectal Surgery, Cleveland Clinic Foundation, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.1097/SLA.0b013e318187ed64DOI Listing
October 2008

Using technology to promote gastrointestinal outcomes research: a case for electronic health records.

Am J Gastroenterol 2008 Sep;103(9):2171-8

Medicine Institute, Cleveland Clinic, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.1111/j.1572-0241.2008.01890.xDOI Listing
September 2008

The expanding universe of inflammatory bowel disease genetics.

Curr Opin Gastroenterol 2008 Jul;24(4):429-34

Center for Inflammatory Bowel Disease, Department of Gastroenterology & Hepatology, Cleveland Clinic, Cleveland, Ohio 44195, USA.

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http://dx.doi.org/10.1097/MOG.0b013e3283009c92DOI Listing
July 2008

IL23R and ATG16L1 SNPs in IBD: alphabet soup or something more?

Authors:
Jean-Paul Achkar

Am J Gastroenterol 2008 Mar;103(3):628-30

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http://dx.doi.org/10.1111/j.1572-0241.2007.01656.xDOI Listing
March 2008

Ulcerative colitis: responding to the challenges.

Authors:
Jean-Paul Achkar

Cleve Clin J Med 2007 Sep;74(9):657-60

Department of Gastroenterology and Hepatology, Cleveland Clinic, OH 44195, USA.

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http://dx.doi.org/10.3949/ccjm.74.9.657DOI Listing
September 2007

Differentiating risk factors for acute and chronic pouchitis.

Clin Gastroenterol Hepatol 2005 Jan;3(1):60-6

Department of Gastroenterology, Cleveland Clinic Foundation, 9500 Euclid Avenue, Desk A30, Cleveland, Ohio 44195, USA.

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http://dx.doi.org/10.1016/s1542-3565(04)00604-4DOI Listing
January 2005

Comprehensive evaluation of inflammatory and noninflammatory sequelae of ileal pouch-anal anastomoses.

Am J Gastroenterol 2005 Jan;100(1):93-101

Center for Inflammatory Bowel Disease, Departments of Gastroenterology/Hepatology, The Cleveland Clinic Foundation, Cleveland, Ohio.

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http://dx.doi.org/10.1111/j.1572-0241.2005.40778.xDOI Listing
January 2005

Endoscopic balloon dilation of ileal pouch strictures.

Am J Gastroenterol 2004 Dec;99(12):2340-7

Department of Gastroenterology/Hepatology, Center for Inflammatory Bowel Disease, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.

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http://dx.doi.org/10.1111/j.1572-0241.2004.40604.xDOI Listing
December 2004

A genome scan in 260 inflammatory bowel disease-affected relative pairs.

Inflamm Bowel Dis 2004 Sep;10(5):513-20

Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pennsylvania 15261, USA.

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http://dx.doi.org/10.1097/00054725-200409000-00004DOI Listing
September 2004

Treatment of rectal cuff inflammation (cuffitis) in patients with ulcerative colitis following restorative proctocolectomy and ileal pouch-anal anastomosis.

Am J Gastroenterol 2004 Aug;99(8):1527-31

Center for Inflammatory Bowel Disease, Departments of Gastroenterology/Hepatology, Anatomic Pathology, and Colorectal Surgery, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.

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http://www.nature.com/doifinder/10.1111/j.1572-0241.2004.305
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http://dx.doi.org/10.1111/j.1572-0241.2004.30518.xDOI Listing
August 2004

Indicators of clinical response to treatment with six-mercaptopurine or azathioprine in patients with inflammatory bowel disease.

Inflamm Bowel Dis 2004 Jul;10(4):339-45

Center for Inflammatory Bowel Disease, Departments of Gastroenterology and Biostatistics, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.

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http://dx.doi.org/10.1097/00054725-200407000-00003DOI Listing
July 2004

Afferent limb ulcers predict Crohn's disease in patients with ileal pouch-anal anastomosis.

Gastroenterology 2004 Jun;126(7):1686-91

Department of Gastroenterology, The Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.1053/j.gastro.2004.02.019DOI Listing
June 2004

Fecal lactoferrin for diagnosis of symptomatic patients with ileal pouch-anal anastomosis.

Gastroenterology 2004 May;126(5):1280-6

Department of Gastroenterology, Center for Inflammatory Bowel Disease, Cleveland Clinic Foundation, Desk A30, 9500 Euclid Avenue, Cleveland, OH 44195, USA.

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http://dx.doi.org/10.1053/j.gastro.2004.02.012DOI Listing
May 2004

Type of fistula determines response to infliximab in patients with fistulous Crohn's disease.

Am J Gastroenterol 2004 Mar;99(3):445-9

Center for Inflammatory Bowel Disease, Department of Gastroenterology, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.

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http://dx.doi.org/10.1111/j.1572-0241.2004.04083.xDOI Listing
March 2004

A genome scan in 260 inflammatory bowel disease-affected relative pairs.

Inflamm Bowel Dis 2004 Jan;10(1):15-22

Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1097/00054725-200401000-00002DOI Listing
January 2004

MDR1 Ala893 polymorphism is associated with inflammatory bowel disease.

Am J Hum Genet 2003 Dec 7;73(6):1282-92. Epub 2003 Nov 7.

The Harvey M. and Lyn P. Meyerhoff Inflammatory Bowel Disease Center, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1180394PMC
http://dx.doi.org/10.1086/379927DOI Listing
December 2003

A cost-effectiveness analysis of diagnostic strategies for symptomatic patients with ileal pouch-anal anastomosis.

Am J Gastroenterol 2003 Nov;98(11):2460-7

Center for Inflammatory Bowel Disease: Department of Gastroenterology, I H Page Center for Health Outcomes Research, Department of Colorectal Surgery, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.

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http://dx.doi.org/10.1111/j.1572-0241.2003.07710.xDOI Listing
November 2003

Defining complex contributions of NOD2/CARD15 gene mutations, age at onset, and tobacco use on Crohn's disease phenotypes.

Inflamm Bowel Dis 2003 Sep;9(5):281-9

The Harvey M. and Lyn P. Meyerhoff Inflammatory Bowel Disease Center, Dept. of Medicine, Johns Hopkins University School of Medicine, Baltimore, Maryland 21231, U.S.A.

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http://dx.doi.org/10.1097/00054725-200309000-00001DOI Listing
September 2003

Evidence for an inflammatory bowel disease locus on chromosome 3p26: linkage, transmission/disequilibrium and partitioning of linkage.

Hum Mol Genet 2002 Oct;11(21):2599-606

Division of Gastroenterology, Hepatology and Nutrition, Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1093/hmg/11.21.2599DOI Listing
October 2002

Predictors of response to infliximab in patients with Crohn's disease.

Gastroenterology 2002 Sep;123(3):707-13

Center for Inflammatory Bowel Disease, Department of Gastroenterology, The Cleveland Clinic Foundation, Cleveland, Ohio 44195, USA.

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http://dx.doi.org/10.1053/gast.2002.35390DOI Listing
September 2002

Perinuclear neutrophil antibodies are not markers for genetic susceptibility or indicators of genetic heterogeneity in familial ulcerative colitis.

Am J Gastroenterol 2002 Sep;97(9):2343-9

Department of Gastroenterology, The Cleveland Clinic Foundation, Ohio 44195, USA.

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http://dx.doi.org/10.1111/j.1572-0241.2002.05989.xDOI Listing
September 2002