Publications by authors named "Jean-Luc Wolfender"

100Publications

Paecilosetin Derivatives as Potent Antimicrobial Agents from .

J Nat Prod 2020 10 6;83(10):2915-2922. Epub 2020 Oct 6.

Université Paris-Saclay, CNRS, Institut de Chimie des Substances Naturelles, UPR 2301, 91198, Gif-sur-Yvette, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.jnatprod.0c00444DOI Listing
October 2020

Production of Highly Active Antiparasitic Compounds from the Controlled Halogenation of the Crude Plant Extract.

J Nat Prod 2020 09 9;83(9):2631-2640. Epub 2020 Sep 9.

School of Pharmaceutical Sciences and Institute of Pharmaceutical Sciences of Western Switzerland (ISPSW), University of Geneva, CMU, Rue Michel Servet 1, 1211 Geneva 4, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.jnatprod.0c00433DOI Listing
September 2020

Symphytum officinale L.: Liquid-liquid chromatography isolation of caffeic acid oligomers and evaluation of their influence on pro-inflammatory cytokine release in LPS-stimulated neutrophils.

J Ethnopharmacol 2020 Nov 31;262:113169. Epub 2020 Jul 31.

Department of Pharmacognosy, Grigore T. Popa University of Medicine and Pharmacy Iasi, 700115, Iasi, Romania; Biothermodynamics, TUM School of Life and Food Sciences Weihenstephan, Technical University of Munich, 85354, Freising, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jep.2020.113169DOI Listing
November 2020

Surface sensing triggers a broad-spectrum antimicrobial response in Pseudomonas aeruginosa.

Environ Microbiol 2020 Aug 10;22(8):3572-3587. Epub 2020 Jul 10.

Transplant Infectious Diseases Unit, University Hospital Geneva, Geneva, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/1462-2920.15139DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7496599PMC
August 2020

Antiseizure potential of the ancient Greek medicinal plant Helleborus odorus subsp. cyclophyllus and identification of its main active principles.

J Ethnopharmacol 2020 Sep 21;259:112954. Epub 2020 May 21.

School of Pharmaceutical Sciences, Institute of Pharmaceutical Sciences of Western Switzerland, University of Geneva, CMU - Rue Michel Servet 1, CH-1211, Geneva 4, Switzerland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jep.2020.112954DOI Listing
September 2020

Wound- and mechanostimulated electrical signals control hormone responses.

New Phytol 2020 08 2;227(4):1037-1050. Epub 2020 Jun 2.

Department of Plant Molecular Biology, Biophore, University of Lausanne, Lausanne, CH-1015, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/nph.16646DOI Listing
August 2020

Zebrafish bioassay-guided isolation of antiseizure compounds from the Cameroonian medicinal plant Cyperus articulatus L.

Phytomedicine 2020 Jan 23;70:153175. Epub 2020 Jan 23.

Institute of Pharmaceutical Sciences of Western Switzerland, CMU - Rue Michel-Servet 1, Geneva 4 CH-1211, Switzerland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.phymed.2020.153175DOI Listing
January 2020

A database of high-resolution MS/MS spectra for lichen metabolites.

Sci Data 2019 11 28;6(1):294. Epub 2019 Nov 28.

CNRS, BioCIS (Biomolécules: Conception Isolement et Synthèse)-UMR 8076, Univ Paris-Sud, Université Paris-Saclay, 5, rue J.-B. Clément, F-92290, Châtenay-Malabry, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41597-019-0305-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6882832PMC
November 2019

Taxonomically Informed Scoring Enhances Confidence in Natural Products Annotation.

Front Plant Sci 2019 25;10:1329. Epub 2019 Oct 25.

Institute of Pharmaceutical Sciences of Western Switzerland (ISPSO), University of Geneva, Centre Médical Universitaire (CMU), Geneva, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fpls.2019.01329DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6824209PMC
October 2019

Puerariae lobatae root extracts and the regulation of brown fat activity.

Phytomedicine 2019 Nov 23;64:153075. Epub 2019 Aug 23.

HanseMerkur Center for Traditional Chinese Medicine at the University Medical Center Hamburg-Eppendorf, Breitenfelder Straße 15, D-20251 Hamburg, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.phymed.2019.153075DOI Listing
November 2019

Discovery of Lipid Peroxidation Inhibitors from Species Prioritized through Multivariate Data Analysis and Multi-Informative Molecular Networking.

Molecules 2019 Aug 17;24(16). Epub 2019 Aug 17.

Department of Pharmaceutical Chemistry and Pharmacognosy, Faculty of Pharmaceutical Sciences and Center of Excellence for Innovation in Chemistry, Naresuan University, Phitsanulok 65000, Thailand.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/molecules24162989DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6719142PMC
August 2019

Quantitative CE analysis of punicalagin in Combretum aculeatum extracts traditionally used in Senegal for the treatment of tuberculosis.

Electrophoresis 2019 11 20;40(21):2820-2827. Epub 2019 Sep 20.

School of Pharmaceutical Sciences, University of Geneva, University of Lausanne, Geneva, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/elps.201900240DOI Listing
November 2019

Identification of chemotypes in bitter melon by metabolomics: a plant with potential benefit for management of diabetes in traditional Chinese medicine.

Metabolomics 2019 07 18;15(8):104. Epub 2019 Jul 18.

School of Pharmaceutical Sciences, EPGL, University of Geneva, University of Lausanne, CMU - Rue Michel-Servet 1, CH-1206, Geneva 4, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11306-019-1565-7DOI Listing
July 2019

Innovative omics-based approaches for prioritisation and targeted isolation of natural products - new strategies for drug discovery.

Nat Prod Rep 2019 06;36(6):855-868

School of Pharmaceutical Sciences, University of Geneva, University of Lausanne, CMU - Rue Michel Servet 1, 1211 Geneva 11, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/c9np00004fDOI Listing
June 2019

Structural Identification of Antibacterial Lipids from Amazonian Palm Tree Endophytes through the Molecular Network Approach.

Int J Mol Sci 2019 Apr 24;20(8). Epub 2019 Apr 24.

CNRS-Institut de Chimie des Substances Naturelles, UPR2301, Université Paris-Saclay, 91198 Gif-sur-Yvette CEDEX, France.

View Article

Download full-text PDF

Source
https://www.mdpi.com/1422-0067/20/8/2006
Publisher Site
http://dx.doi.org/10.3390/ijms20082006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514718PMC
April 2019

Utility of dry load injection for an efficient natural products isolation at the semi-preparative chromatographic scale.

J Chromatogr A 2019 Aug 21;1598:85-91. Epub 2019 Mar 21.

School of Pharmaceutical Sciences, EPGL, University of Geneva, University of Lausanne, CMU, 1, Rue Michel Servet, 1211 Geneva 4, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.chroma.2019.03.042DOI Listing
August 2019

The antifungal activity and mechanisms of action of quantified extracts from berries, leaves and roots of Phytolacca tetramera.

Phytomedicine 2019 Jul 16;60:152884. Epub 2019 Mar 16.

Área Farmacognosia, Facultad de Ciencias Bioquímicas y Farmacéuticas, Universidad Nacional de Rosario (UNR), Suipacha 531, 2000 Rosario, Argentina. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.phymed.2019.152884DOI Listing
July 2019

Antimycobacterial activity in a single-cell infection assay of ellagitannins from Combretum aculeatum and their bioavailable metabolites.

J Ethnopharmacol 2019 Jun 23;238:111832. Epub 2019 Mar 23.

School of Pharmaceutical Sciences, University of Geneva, University of Lausanne, CMU - Rue Michel Servet 1, 1211, Geneva 11, Switzerland. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S03788741183363
Publisher Site
http://dx.doi.org/10.1016/j.jep.2019.111832DOI Listing
June 2019

Characterization, Diversity, and Structure-Activity Relationship Study of Lipoamino Acids from sp. and Synthetic Analogues.

Int J Mol Sci 2019 Mar 2;20(5). Epub 2019 Mar 2.

CNRS, Institut de Chimie des Substances Naturelles, UPR 2301, Université Paris-Saclay, 1 avenue de la Terrasse, 91198 Gif-sur-Yvette, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijms20051083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6429151PMC
March 2019

Differentiation of Ficus deltoidea varieties and chemical marker determination by UHPLC-TOFMS metabolomics for establishing quality control criteria of this popular Malaysian medicinal herb.

Metabolomics 2019 03 4;15(3):35. Epub 2019 Mar 4.

School of Pharmaceutical Sciences, EPGL, University of Geneva, University of Lausanne, Rue Michel-Servet 1, 1206, Geneva, Switzerland.

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s11306-019-1489-2
Publisher Site
http://dx.doi.org/10.1007/s11306-019-1489-2DOI Listing
March 2019

High-performance counter-current chromatography isolation and initial neuroactivity characterization of furanocoumarin derivatives from Peucedanum alsaticum L (Apiaceae).

Phytomedicine 2019 Feb 26;54:259-264. Epub 2018 Oct 26.

Department of Pharmacognosy with Medicinal Plant Unit, Medical University of Lublin, 1 Chodźki Str., 20-093 Lublin, Poland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.phymed.2018.10.030DOI Listing
February 2019

Chemo-Diversification of Plant Extracts Using a Generic Bromination Reaction and Monitoring by Metabolite Profiling.

ACS Comb Sci 2019 03 17;21(3):171-182. Epub 2019 Jan 17.

Microbiology Unit, Department of Botany and Plant Biology , University of Geneva , 30 quai Ernest-Ansermet , 1211 Geneva 4, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acscombsci.8b00132DOI Listing
March 2019

Antileishmanial Activity of Dimeric Flavonoids Isolated from .

Molecules 2018 Dec 20;24(1). Epub 2018 Dec 20.

Laboratório de Engenharia Tecidual e Imunofarmacologia, Instituto Gonçalo Moniz, Fundação Oswaldo Cruz (Fiocruz), Avenida Waldemar Falcão, 121, Candeal⁻Salvador-BA 40296-710, Brazil.

View Article

Download full-text PDF

Source
http://www.mdpi.com/1420-3049/24/1/1
Publisher Site
http://dx.doi.org/10.3390/molecules24010001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6337281PMC
December 2018

Tannins from Syzygium guineense suppress Wnt signaling and proliferation of Wnt-dependent tumors through a direct effect on secreted Wnts.

Cancer Lett 2018 10 9;435:110-120. Epub 2018 Aug 9.

Department of Pharmacology and Toxicology, University of Lausanne, Switzerland; School of Biomedicine, Far Eastern Federal University, Vladivostok, Russia. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S03043835183051
Publisher Site
http://dx.doi.org/10.1016/j.canlet.2018.08.003DOI Listing
October 2018

Anti-inflammatory and antiproliferative diterpenoids from Plectranthus scutellarioides.

Phytochemistry 2018 Oct 28;154:39-46. Epub 2018 Jun 28.

School of Pharmaceutical Sciences, University of Geneva, University of Lausanne, Rue Michel-Servet 1, 1211 Geneva 4, Switzerland. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S00319422183023
Publisher Site
http://dx.doi.org/10.1016/j.phytochem.2018.06.012DOI Listing
October 2018

Phytochemical Composition of the Decoctions of Greek Edible Greens (Chórta) and Evaluation of Antioxidant and Cytotoxic Properties.

Molecules 2018 06 26;23(7). Epub 2018 Jun 26.

Department of Pharmacognosy and Natural Products Chemistry, Faculty of Pharmacy, National and Kapodistrian University of Athens, Panepistimiopolis Zografou, 15771 Athens, Greece.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/molecules23071541DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100566PMC
June 2018

Dereplication of plant phenolics using a mass-spectrometry database independent method.

Phytochem Anal 2018 Nov 29;29(6):601-612. Epub 2018 May 29.

Complex Carbohydrate Research Centre (CCRC), Departments of Genetics and Biochemistry, Institute of Bioinformatics, University of Georgia, Athens, GA, USA.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/pca.2773
Publisher Site
http://dx.doi.org/10.1002/pca.2773DOI Listing
November 2018

Isolation and Antimicrobial Activity of Coumarin Derivatives from Fruits of Tamamsch.

Molecules 2018 May 20;23(5). Epub 2018 May 20.

Department of Pharmacognosy with Medicinal Plant Unit, Medical University of Lublin, Chodzki, 120-093 Lublin, Poland.

View Article

Download full-text PDF

Source
http://www.mdpi.com/1420-3049/23/5/1222
Publisher Site
http://dx.doi.org/10.3390/molecules23051222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6100078PMC
May 2018

Lung Cancer Chemopreventive Activity of Patulin Isolated from Penicillium vulpinum.

Molecules 2018 Mar 12;23(3). Epub 2018 Mar 12.

School of Pharmaceutical Sciences, University of Geneva, University of Lausanne, 1 Rue Michel-Servet, CH-1211 Geneva 4, Switzerland.

View Article

Download full-text PDF

Source
http://www.mdpi.com/1420-3049/23/3/636
Publisher Site
http://dx.doi.org/10.3390/molecules23030636DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6017800PMC
March 2018

Structural design, synthesis and substituent effect of hydrazone-N-acylhydrazones reveal potent immunomodulatory agents.

Bioorg Med Chem 2018 05 25;26(8):1971-1985. Epub 2018 Feb 25.

FIOCRUZ, Instituto Gonçalo Moniz, 40296-710 Salvador, BA, Brazil; Centro de Biotecnologia e Terapia Celular, Hospital São Rafael, 41253-190 Salvador, BA, Brazil. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bmc.2018.02.047DOI Listing
May 2018

Pharmacognosy in the digital era: shifting to contextualized metabolomics.

Curr Opin Biotechnol 2018 12 27;54:57-64. Epub 2018 Feb 27.

School of Pharmaceutical Sciences, University of Geneva, University of Lausanne, Rue Michel-Servet 1, CH-1211 Geneva 4, Switzerland.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S09581669173025
Publisher Site
http://dx.doi.org/10.1016/j.copbio.2018.02.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6110999PMC
December 2018

Dynamics of Metabolite Induction in Fungal Co-cultures by Metabolomics at Both Volatile and Non-volatile Levels.

Front Microbiol 2018 5;9:72. Epub 2018 Feb 5.

School of Pharmaceutical Sciences (EPGL), University of Geneva, University of Lausanne, Centre Médical Universitaire (CMU), Geneva, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fmicb.2018.00072DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5807337PMC
February 2018

Survey on medicinal plants traditionally used in Senegal for the treatment of tuberculosis (TB) and assessment of their antimycobacterial activity.

J Ethnopharmacol 2018 Apr 28;216:71-78. Epub 2017 Dec 28.

School of Pharmaceutical Sciences, University of Geneva, University of Lausanne, CMU - Rue Michel Servet 1, 1211 Geneva 11, Switzerland. Electronic address:

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S03788741173226
Publisher Site
http://dx.doi.org/10.1016/j.jep.2017.12.037DOI Listing
April 2018

Targeted Isolation of Monoterpene Indole Alkaloids from Palicourea sessilis.

J Nat Prod 2017 11 9;80(11):3032-3037. Epub 2017 Nov 9.

Laboratory of Pharmacognosy and Quality Control of Phytomedicines, Faculty of Pharmacy, Universidade Federal do Rio Grande do Sul-UFRGS , 90610-000, Porto Alegre/RS, Brazil.

View Article

Download full-text PDF

Source
http://pubs.acs.org/doi/10.1021/acs.jnatprod.7b00681
Publisher Site
http://dx.doi.org/10.1021/acs.jnatprod.7b00681DOI Listing
November 2017

Cytotoxic Prenylated Stilbenes Isolated from Macaranga tanarius.

J Nat Prod 2017 10 3;80(10):2684-2691. Epub 2017 Oct 3.

Institut de Chimie des Substances Naturelles, CNRS, ICSN UPR2301, University of Paris-Saclay , 91198, Gif-sur-Yvette, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.jnatprod.7b00409DOI Listing
October 2017

Unguiculin A and Ptilomycalins E-H, Antimalarial Guanidine Alkaloids from the Marine Sponge Monanchora unguiculata.

J Nat Prod 2017 05 3;80(5):1404-1410. Epub 2017 Apr 3.

Laboratoire de Chimie des Substances Naturelles et des Sciences des Aliments, Faculté des Sciences et Technologies, Université de La Réunion , 15 Avenue René Cassin, CS 92003, 97744 Saint-Denis Cedex 9, La Réunion, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.jnatprod.6b01079DOI Listing
May 2017

Combining ANOVA-PCA with POCHEMON to analyse micro-organism development in a polymicrobial environment.

Anal Chim Acta 2017 04 13;963:1-16. Epub 2017 Feb 13.

Department of Analytical Chemistry, Institute for Molecules and Materials, Radboud University, Nijmegen, The Netherlands. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.aca.2017.01.064DOI Listing
April 2017

Generation of Antifungal Stilbenes Using the Enzymatic Secretome of Botrytis cinerea.

J Nat Prod 2017 04 23;80(4):887-898. Epub 2017 Mar 23.

School of Pharmaceutical Sciences, EPGL, University of Geneva, University of Lausanne , CMU, 1, Rue Michel Servet, 1211 Geneva 4, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.jnatprod.6b00760DOI Listing
April 2017

Passive Intestinal Absorption of Representative Plant Secondary Metabolites: A Physicochemical Study.

Planta Med 2017 May 13;83(8):718-726. Epub 2017 Feb 13.

School of Pharmaceutical Sciences, EPGL, University of Geneva, University of Lausanne, Geneva, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1055/s-0043-101915DOI Listing
May 2017

Deep metabolome annotation in natural products research: towards a virtuous cycle in metabolite identification.

Curr Opin Chem Biol 2017 02 12;36:40-49. Epub 2017 Jan 12.

School of Pharmaceutical Sciences, University of Geneva, University of Lausanne, CMU-Rue Michel Servet 1, 1211 Geneva 11, Switzerland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cbpa.2016.12.022DOI Listing
February 2017

Dibenzofurans and Pseudodepsidones from the Lichen Stereocaulon paschale Collected in Northern Quebec.

J Nat Prod 2017 01 12;80(1):210-214. Epub 2017 Jan 12.

Groupe de Recherche en Écologie Buccale, Faculté de Médecine Dentaire, Université Laval , 2420 Rue de la Terrasse, Québec G1V 0A6, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.jnatprod.6b00831DOI Listing
January 2017

Current and Future Perspectives on the Structural Identification of Small Molecules in Biological Systems.

Metabolites 2016 Dec 15;6(4). Epub 2016 Dec 15.

Departments of Computing Science and Biological Sciences, University of Alberta, Edmonton, T6G 2E8 AB, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/metabo6040046DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5192452PMC
December 2016

UHPLC-MS-based HDAC Assay Applied to Bio-guided Microfractionation of Fungal Extracts.

Phytochem Anal 2017 Mar 5;28(2):93-100. Epub 2016 Dec 5.

School of Pharmaceutical Sciences, University of Geneva, University of Lausanne, CMU - Rue Michel Servet 1, 1211, Geneva, 11, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pca.2652DOI Listing
March 2017

Advances in venomics.

Mol Biosyst 2016 11;12(12):3530-3543

Atheris SA, Chemin d'Alcire 1, CH-1228 Plan-les-Ouates, Geneva, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/c6mb00516kDOI Listing
November 2016

Conjugation of N-acylhydrazone and 1,2,4-oxadiazole leads to the identification of active antimalarial agents.

Bioorg Med Chem 2016 11 9;24(22):5693-5701. Epub 2016 Sep 9.

Centro de Pesquisas Gonçalo Moniz, Fundação Oswaldo Cruz, CEP 40296-710 Salvador, BA, Brazil; Centro de Biotecnologia e Terapia Celular, Hospital São Rafael, CEP 41253-190 Salvador, BA, Brazil.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bmc.2016.09.013DOI Listing
November 2016

Highly localized and persistent induction of Bx1-dependent herbivore resistance factors in maize.

Plant J 2016 12 18;88(6):976-991. Epub 2016 Oct 18.

Institute of Plant Sciences, University of Bern, Altenbergrain 21, 3013, Bern, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/tpj.13308DOI Listing
December 2016

Targeted Isolation of Indolopyridoquinazoline Alkaloids from Conchocarpus fontanesianus Based on Molecular Networks.

J Nat Prod 2016 09 24;79(9):2270-8. Epub 2016 Aug 24.

School of Pharmaceutical Sciences, EPGL, University of Geneva, University of Lausanne , 30 quai Ernest-Ansermet, CH-1211 Geneva 4, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.jnatprod.6b00379DOI Listing
September 2016

Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking.

Authors:
Mingxun Wang Jeremy J Carver Vanessa V Phelan Laura M Sanchez Neha Garg Yao Peng Don Duy Nguyen Jeramie Watrous Clifford A Kapono Tal Luzzatto-Knaan Carla Porto Amina Bouslimani Alexey V Melnik Michael J Meehan Wei-Ting Liu Max Crüsemann Paul D Boudreau Eduardo Esquenazi Mario Sandoval-Calderón Roland D Kersten Laura A Pace Robert A Quinn Katherine R Duncan Cheng-Chih Hsu Dimitrios J Floros Ronnie G Gavilan Karin Kleigrewe Trent Northen Rachel J Dutton Delphine Parrot Erin E Carlson Bertrand Aigle Charlotte F Michelsen Lars Jelsbak Christian Sohlenkamp Pavel Pevzner Anna Edlund Jeffrey McLean Jörn Piel Brian T Murphy Lena Gerwick Chih-Chuang Liaw Yu-Liang Yang Hans-Ulrich Humpf Maria Maansson Robert A Keyzers Amy C Sims Andrew R Johnson Ashley M Sidebottom Brian E Sedio Andreas Klitgaard Charles B Larson Cristopher A Boya P Daniel Torres-Mendoza David J Gonzalez Denise B Silva Lucas M Marques Daniel P Demarque Egle Pociute Ellis C O'Neill Enora Briand Eric J N Helfrich Eve A Granatosky Evgenia Glukhov Florian Ryffel Hailey Houson Hosein Mohimani Jenan J Kharbush Yi Zeng Julia A Vorholt Kenji L Kurita Pep Charusanti Kerry L McPhail Kristian Fog Nielsen Lisa Vuong Maryam Elfeki Matthew F Traxler Niclas Engene Nobuhiro Koyama Oliver B Vining Ralph Baric Ricardo R Silva Samantha J Mascuch Sophie Tomasi Stefan Jenkins Venkat Macherla Thomas Hoffman Vinayak Agarwal Philip G Williams Jingqui Dai Ram Neupane Joshua Gurr Andrés M C Rodríguez Anne Lamsa Chen Zhang Kathleen Dorrestein Brendan M Duggan Jehad Almaliti Pierre-Marie Allard Prasad Phapale Louis-Felix Nothias Theodore Alexandrov Marc Litaudon Jean-Luc Wolfender Jennifer E Kyle Thomas O Metz Tyler Peryea Dac-Trung Nguyen Danielle VanLeer Paul Shinn Ajit Jadhav Rolf Müller Katrina M Waters Wenyuan Shi Xueting Liu Lixin Zhang Rob Knight Paul R Jensen Bernhard O Palsson Kit Pogliano Roger G Linington Marcelino Gutiérrez Norberto P Lopes William H Gerwick Bradley S Moore Pieter C Dorrestein Nuno Bandeira

Nat Biotechnol 2016 08;34(8):828-837

Center for Computational Mass Spectrometry, UC San Diego, La Jolla, United States.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nbt.3597DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321674PMC
August 2016

Antioxidant and antibacterial activities and polyphenolic constituents of Helianthemum sessiliflorum Pers.

Nat Prod Res 2017 Mar 15;31(6):686-690. Epub 2016 Jul 15.

a Laboratoire de Chimie et Chimie de l'Environnement (L.C.C.E), Faculté des Sciences de la Matière, Département de Chimie , Université de Batna-1 , Batna , Algérie.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14786419.2016.1209669DOI Listing
March 2017

Nauclea latifolia: biological activity and alkaloid phytochemistry of a West African tree.

Nat Prod Rep 2016 Sep 27;33(9):1034-43. Epub 2016 Jun 27.

Univ. Grenoble Alpes, DPM UMR 5063, F-38041 Grenoble, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/c6np00039hDOI Listing
September 2016

Paired Hierarchical Organization of 13-Lipoxygenases in Arabidopsis.

Plants (Basel) 2016 Mar 24;5(2). Epub 2016 Mar 24.

Department of Plant Molecular Biology, University of Lausanne, CH-1015 Lausanne, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/plants5020016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931396PMC
March 2016

Production of Fusaric Acid by Fusarium spp. in Pure Culture and in Solid Medium Co-Cultures.

Molecules 2016 Mar 18;21(3):370. Epub 2016 Mar 18.

School of Pharmaceutical Sciences, EPGL, University of Geneva, University of Lausanne, Quai Ernest-Ansermet 30, CH-1211 Geneva 4, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/molecules21030370DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274276PMC
March 2016

Statistical Correlations between HPLC Activity-Based Profiling Results and NMR/MS Microfraction Data to Deconvolute Bioactive Compounds in Mixtures.

Molecules 2016 Feb 24;21(3):259. Epub 2016 Feb 24.

School of Pharmaceutical Sciences, University of Geneva, University of Lausanne, Quai Ernest-Ansermet 30, CH-1211 Geneva 4, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/molecules21030259DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6274519PMC
February 2016

Integration of Molecular Networking and In-Silico MS/MS Fragmentation for Natural Products Dereplication.

Anal Chem 2016 Mar 1;88(6):3317-23. Epub 2016 Mar 1.

School of Pharmaceutical Sciences, EPGL, University of Geneva, University of Lausanne , Quai Ernest-Ansermet 30, CH-1211 Geneva 4, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.analchem.5b04804DOI Listing
March 2016

Prediction of the Passive Intestinal Absorption of Medicinal Plant Extract Constituents with the Parallel Artificial Membrane Permeability Assay (PAMPA).

Planta Med 2016 Mar 12;82(5):424-31. Epub 2016 Feb 12.

School of Pharmaceutical Sciences, EPGL, University of Geneva, University of Lausanne, Geneva, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1055/s-0042-101247DOI Listing
March 2016

Antifungal Quinoline Alkaloids from Waltheria indica.

J Nat Prod 2016 Feb 5;79(2):300-7. Epub 2016 Feb 5.

School of Pharmaceutical Sciences, University of Geneva, University of Lausanne , Quai Ernest-Ansermet 30, 1211 Geneva 4, Switzerland.

View Article

Download full-text PDF

Source
http://pubs.acs.org/doi/10.1021/acs.jnatprod.5b00896
Publisher Site
http://dx.doi.org/10.1021/acs.jnatprod.5b00896DOI Listing
February 2016

Cell-based bioreporter assay coupled to HPLC micro-fractionation in the evaluation of antimicrobial properties of the basidiomycete fungus Pycnoporus cinnabarinus.

Pharm Biol 2016 25;54(6):1108-15. Epub 2016 Jan 25.

a Centre for Drug Research, Division of Pharmaceutical Biosciences, Faculty of Pharmacy , University of Helsinki , Helsinki , Finland ;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3109/13880209.2015.1103754DOI Listing
January 2017

Anti-Candida Cassane-Type Diterpenoids from the Root Bark of Swartzia simplex.

J Nat Prod 2015 Dec 11;78(12):2994-3004. Epub 2015 Dec 11.

School of Pharmaceutical Sciences, EPGL, University of Geneva, University of Lausanne , 30 quai Ernest-Ansermet, CH-1211 Geneva 4, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/acs.jnatprod.5b00744DOI Listing
December 2015

A Physiological and Behavioral Mechanism for Leaf Herbivore-Induced Systemic Root Resistance.

Plant Physiol 2015 Dec 1;169(4):2884-94. Epub 2015 Oct 1.

Institute of Plant Sciences, University of Bern, Altenbergrain 21, 3013 Bern, Switzerland (M.E., C.A.M.R.);Root-Herbivore Interactions Group, Department of Biochemistry (M.E., C.A.M.R., J.L.), and Department of Biochemistry (J.G.), Max Planck Institute for Chemical Ecology, DE-07745 Jena, Germany;Laboratory for Fundamental and Applied Research in Chemical Ecology, University of Neuchâtel, CH-2009 Neuchatel, Switzerland (M.E., C.A.M.R., G.R.D., N.V., T.C.J.T.);Phytochemistry and Bioactive Natural Products, School of Pharmaceutical Sciences, University of Geneva, University of Lausanne, CH-1211 Geneva 4, Switzerland (G.M., J.-L.W.);Unité de Génétique et d'Amélioration des Plantes Fourragères, INRA, 86600 Lusignan, France (Y.B.); andUnited States Department of Agriculture, Agricultural Research Service, North Central Agricultural Research Laboratory, Brookings, South Dakota 57006 (B.W.F.).

View Article

Download full-text PDF

Source
http://www.plantphysiol.org/content/early/2015/10/01/pp.15.0
Web Search
http://www.plantphysiol.org/content/169/4/2884.full.pdf
Web Search
http://www.plantphysiol.org/lookup/doi/10.1104/pp.15.00759
Publisher Site
http://dx.doi.org/10.1104/pp.15.00759DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4677881PMC
December 2015

Phospholipidosis effect of drugs by adsorption into lipid monolayers.

Colloids Surf B Biointerfaces 2015 Dec 5;136:175-84. Epub 2015 Sep 5.

Department of Chemistry, Biology and Biotechnology, University of Perugia, via Elce di Sotto 8, I-06123 Perugia, Italy. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.colsurfb.2015.09.003DOI Listing
December 2015

Axial and Radial Oxylipin Transport.

Plant Physiol 2015 Nov 3;169(3):2244-54. Epub 2015 Sep 3.

Department of Plant Molecular Biology, University of Lausanne, CH-1015 Lausanne, Switzerland (D.G., A.Cha., I.F.A., A.K., S.S., A.Ché., E.E.F.); andSchool of Pharmaceutical Sciences, University of Geneva, University of Lausanne, CH-1211 Geneva, Switzerland (A.Cha., J.-L.W.)

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1104/pp.15.01104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4634084PMC
November 2015

Maize Domestication and Anti-Herbivore Defences: Leaf-Specific Dynamics during Early Ontogeny of Maize and Its Wild Ancestors.

PLoS One 2015 12;10(8):e0135722. Epub 2015 Aug 12.

Laboratory of Fundamental and Applied Research in Chemical Ecology, University of Neuchâtel, Rue Emile-Argand 11, 2000, Neuchâtel, Switzerland; Neuchâtel Platform of Analytical Chemistry, University of Neuchâtel, Avenue de Bellevaux 51, 2000, Neuchâtel, Switzerland.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0135722PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4534137PMC
May 2016

Transcriptome diversity among rice root types during asymbiosis and interaction with arbuscular mycorrhizal fungi.

Proc Natl Acad Sci U S A 2015 May 6;112(21):6754-9. Epub 2015 May 6.

Department of Plant Molecular Biology, University of Lausanne, 1015 Lausanne, Switzerland; Department of Plant Sciences, University of Cambridge, Cambridge, CB2 3EA, United Kingdom; and

View Article

Download full-text PDF

Source
http://www.pnas.org/lookup/doi/10.1073/pnas.1504142112
Publisher Site
http://dx.doi.org/10.1073/pnas.1504142112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4450400PMC
May 2015

Rational and Efficient Preparative Isolation of Natural Products by MPLC-UV-ELSD based on HPLC to MPLC Gradient Transfer.

Planta Med 2015 Nov 29;81(17):1636-43. Epub 2015 Apr 29.

School of Pharmaceutical Sciences, EPGL, University of Geneva, University of Lausanne, Geneva, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1055/s-0035-1545912DOI Listing
November 2015

Current approaches and challenges for the metabolite profiling of complex natural extracts.

J Chromatogr A 2015 Feb 31;1382:136-64. Epub 2014 Oct 31.

School of Pharmaceutical Sciences, EPGL, University of Geneva, University of Lausanne, quai Ernest-Ansermet 30, CH-1211 Geneva 4, Switzerland; Groupe Mer, Molécules, Santé-EA 2160, UFR des Sciences Pharmaceutiques et Biologiques, Université de Nantes, 9 rue Bias, BP 53508, F-44035 Nantes Cedex 01, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.chroma.2014.10.091DOI Listing
February 2015

Within-plant distribution of 1,4-benzoxazin-3-ones contributes to herbivore niche differentiation in maize.

Plant Cell Environ 2015 Jun 28;38(6):1081-93. Epub 2014 Nov 28.

Laboratory of Fundamental and Applied Research in Chemical Ecology, University of Neuchâtel, Neuchâtel, 2000, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/pce.12464DOI Listing
June 2015

Study of leaf metabolome modifications induced by UV-C radiations in representative Vitis, Cissus and Cannabis species by LC-MS based metabolomics and antioxidant assays.

Molecules 2014 Sep 5;19(9):14004-21. Epub 2014 Sep 5.

Station de recherche Agroscope, Institut des Sciences en Production Végétale IPV, Route de Duiller 50, P.O. Box 1012, Nyon 1260, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/molecules190914004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271074PMC
September 2014

Zebrafish bioassay-guided microfractionation identifies anticonvulsant steroid glycosides from the Philippine medicinal plant Solanum torvum.

ACS Chem Neurosci 2014 Oct 8;5(10):993-1004. Epub 2014 Sep 8.

School of Pharmaceutical Sciences, University of Geneva, University of Lausanne , 30, quai Ernest-Ansermet, CH-1211 Geneva 4, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1021/cn5001342DOI Listing
October 2014

Microphynolides A and B, new spiro-γ-lactone glycosides from Thymelaea microphylla.

Nat Prod Res 2014 30;28(20):1732-8. Epub 2014 Jul 30.

a Laboratoire de Chimie et Chimie de l'Environnement (L.C.C.E), Département de Chimie , Faculté des Sciences, Université de Batna , Batna , Algérie.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/14786419.2014.942662DOI Listing
April 2015

Multi-well fungal co-culture for de novo metabolite-induction in time-series studies based on untargeted metabolomics.

Mol Biosyst 2014 Jul;10(9):2289-98

School of Pharmaceutical Sciences, EPGL, University of Geneva, University of Lausanne, quai Ernest-Ansermet 30, CH-1211 Geneva 4, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1039/c4mb00223gDOI Listing
July 2014