Publications by authors named "Jean-Louis Guéant"

100Publications

The Fate of Transplanted Olfactory Progenitors Is Conditioned by the Cell Phenotypes of the Receiver Brain Tissue in Cocultures.

Int J Mol Sci 2020 09 30;21(19). Epub 2020 Sep 30.

Inserm UMR1256/NGERE, Faculté de Medecine, 9 Avenue de la Forêt de Haye, Université de Lorraine, F-54000 Nancy, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijms21197249DOI Listing
September 2020

Telomere length in granulosa cells and leukocytes: a potential marker of female fertility? A systematic review of the literature.

J Ovarian Res 2020 Aug 21;13(1):96. Epub 2020 Aug 21.

Laboratory of Biology of Reproduction-CECOS Lorraine, University Hospital of Nancy, 10 rue du Dr Heydenreich, 54000, Nancy, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s13048-020-00702-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7442985PMC
August 2020

[Phenylketonuria, from diet to gene therapy].

Med Sci (Paris) 2020 Aug-Sep;36(8-9):725-734. Epub 2020 Aug 21.

Centre de référence des maladies métaboliques, Service de pédiatrie, CHRU de Nancy, 54000 Nancy, France - Inserm UMR_S 1256 (NGERE, Nutrition Génétique et Exposition aux Risques Environnementaux), Faculté de médecine de Nancy, Université de Lorraine, 54000 Nancy, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1051/medsci/2020127DOI Listing
October 2020

Sirt1-PPARS Cross-Talk in Complex Metabolic Diseases and Inherited Disorders of the One Carbon Metabolism.

Cells 2020 Aug 11;9(8). Epub 2020 Aug 11.

UMR Inserm 1256 N-GERE (Nutrition, Génetique et Exposition aux Risques Environmentaux), Université de Lorraine, 54500 Vandoeuvre-lès-Nancy, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/cells9081882DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7465293PMC
August 2020

Blood Myeloperoxidase-DNA, a biomarker of early response to SARS-CoV-2 infection?

Allergy 2020 Aug 2. Epub 2020 Aug 2.

Department INSERM, UMR_S1116 Défaillance cardiovasculaire aiguë et chronique, University of Lorraine, Nancy, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/all.14533DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7436665PMC
August 2020

Coronavirus disease 2019: acute Fanconi syndrome precedes acute kidney injury.

Clin Kidney J 2020 Jun 8;13(3):362-370. Epub 2020 Jun 8.

Department of Molecular Medicine, Division of Biochemistry, Molecular Biology, Nutrition, and Metabolism, University of Lorraine, CHRU-Nancy, Vandoeuvre, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/ckj/sfaa109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314200PMC
June 2020

The deficit in folate and vitamin B12 triggers liver macrovesicular steatosis and inflammation in rats with dextran sodium sulfate-induced colitis.

J Nutr Biochem 2020 Oct 20;84:108415. Epub 2020 May 20.

INSERM U1256, Nutrition Génétique et Exposition aux Risques Environnementaux, Medical Faculty, University of Lorraine and Regional University Hospital Center of Nancy, Vandœuvre les Nancy, France; Biochemical and Molecular biology lab, Regional University Hospital Center of Nancy, Vandoeuvre les Nancy, France; Division of Hepatogastroenterology, Regional University Hospital Center of Nancy, Vandoeuvre les Nancy, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jnutbio.2020.108415DOI Listing
October 2020

Medium term post-bariatric surgery deficit of vitamin B12 is predicted by deficit at time of surgery.

Clin Nutr 2020 Apr 25. Epub 2020 Apr 25.

Inserm UMRS 1256 N-GERE (Nutrition-Genetics-Environmental Risks) - University de Lorraine, Faculty of Medicine, Nancy, France; Department of Endocrinology Diabetology and Nutrition, Regional University Hospital of Nancy (CHRU Nancy), Nancy, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clnu.2020.04.029DOI Listing
April 2020

Prolonged 25-OH Vitamin D Deficiency Does Not Impair Bone Mineral Density in Adult Patients With Vitamin D 25-Hydroxylase Deficiency (CYP2R1).

Calcif Tissue Int 2020 Aug 19;107(2):191-194. Epub 2020 May 19.

Reference Center for Inborn Errors of Metabolism, Pediatric Unit, University Hospital of Nancy, Nancy, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00223-020-00704-4DOI Listing
August 2020

Biochemical analysis of patients with mutations in MTHFD1 and a diagnosis of methylenetetrahydrofolate dehydrogenase 1 deficiency.

Mol Genet Metab 2020 07 5;130(3):179-182. Epub 2020 May 5.

Department of Human Genetics, McGill University, Montreal, Quebec, Canada.; Division of Medical Genetics, Department of Specialized Medicine, McGill University Health Centre, Montreal, Quebec, Canada.; Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.; Division of Medical Biochemistry, Department of Specialized Medicine, McGill University Health Centre, Montreal, Quebec, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ymgme.2020.04.008DOI Listing
July 2020

Folinic acid improves the score of Autism in the EFFET placebo-controlled randomized trial.

Biochimie 2020 Jun 7;173:57-61. Epub 2020 May 7.

Inserm UMRS 1256 N-GERE (Nutrition-Genetics-Environmental Risks), Regional University Hospital of Nancy and University of Lorraine, BP 184, 54511, Nancy (Vandoeuvre), France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.biochi.2020.04.019DOI Listing
June 2020

B vitamins and one carbon metabolism micronutrients in health and disease.

Biochimie 2020 06 22;173:1-2. Epub 2020 Apr 22.

Inserm and Medical Faculty of University of Lorraine, Nancy-Vandoeuvre, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.biochi.2020.04.018DOI Listing
June 2020

Comparative accuracy of ferritin, transferrin saturation and soluble transferrin receptor for the diagnosis of iron deficiency in inflammatory bowel disease.

Aliment Pharmacol Ther 2020 06 22;51(11):1087-1095. Epub 2020 Apr 22.

Department of Hepato-Gastroenterology and Inserm NGERE 1256, University Hospital of Nancy, University of Lorraine, Vandoeuvre-lès-Nancy, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/apt.15739DOI Listing
June 2020

Genetic, epigenetic and genomic mechanisms of methionine dependency of cancer and tumor-initiating cells: What could we learn from folate and methionine cycles.

Biochimie 2020 Jun 11;173:123-128. Epub 2020 Apr 11.

INSERM UMR_S 1256 NGERE - Nutrition, Genetics, and Environmental Risk Exposure and National Center of Inborn Errors of Metabolism, University of Lorraine, Nancy (Vandoeuvre-lès-Nancy), F-54000, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.biochi.2020.03.015DOI Listing
June 2020

E-health education interventions on HbA in patients with type 1 diabetes on intensive insulin therapy: A systematic review and meta-analysis of randomized controlled trials.

Diabetes Metab Res Rev 2020 Sep 6;36(6):e3313. Epub 2020 Apr 6.

Université de Lorraine, CHRU-Nancy, Department of Endocrinology, Diabetology and Nutrition, Nancy, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/dmrr.3313DOI Listing
September 2020

Health outcomes associated with vegetarian diets: An umbrella review of systematic reviews and meta-analyses.

Clin Nutr 2020 Mar 11. Epub 2020 Mar 11.

University of Lorraine, INSERM UMR_S 1256, Nutrition, Genetics, and Environmental Risk Exposure (NGERE), Faculty of Medicine of Nancy, F-54000, Nancy, France; Department of Molecular Medicine, Division of Biochemistry, Molecular Biology, and Nutrition, University Hospital of Nancy, F-54000, Nancy, France; Reference Center for Inborn Errors of Metabolism (ORPHA67872), University Hospital of Nancy, F-54000, Nancy, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clnu.2020.02.037DOI Listing
March 2020

Mechanisms of homocysteine-induced damage to the endothelial, medial and adventitial layers of the arterial wall.

Biochimie 2020 Jun 24;173:100-106. Epub 2020 Feb 24.

INSERM U1256 Nutrition-Genetics and Environmental Exposure, Medical Faculty and University Hospital Center, Nancy University, 54500, Vandoeuvre-lès-Nancy, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.biochi.2020.02.012DOI Listing
June 2020

Population and evolutionary genetics of the PAH locus to uncover overdominance and adaptive mechanisms in phenylketonuria: Results from a multiethnic study.

EBioMedicine 2020 Jan 7;51:102623. Epub 2020 Jan 7.

University of Lorraine, INSERM UMR_S 1256, Nutrition, Genetics, and Environmental Risk Exposure (NGERE), Faculty of Medicine of Nancy, Nancy, France; Department of Molecular Medicine, Division of Biochemistry, Molecular Biology, Nutrition, and Metabolism, University Hospital of Nancy, Nancy, France; Reference Centre for Inborn Errors of Metabolism (ORPHA67872), University Hospital of Nancy, Nancy F-54000, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ebiom.2019.102623DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7000351PMC
January 2020

Brain Susceptibility to Methyl Donor Deficiency: From Fetal Programming to Aging Outcome in Rats.

Int J Mol Sci 2019 Nov 14;20(22). Epub 2019 Nov 14.

Faculté de médecine, INSERM 1256/University of Lorraine, F-54500 Vandoeuvre-les-Nancy, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijms20225692DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6888628PMC
November 2019

SIRT1 activation rescues the mislocalization of RNA-binding proteins and cognitive defects induced by inherited cobalamin disorders.

Metabolism 2019 12 28;101:153992. Epub 2019 Oct 28.

Université de Lorraine, Inserm, UMRS 1256, NGERE - Nutrition, Genetics, and Environmental Risk Exposure, F-54000 Nancy, France; Université de Lorraine, CHRU-Nancy, National Center of Inborn Errors of Metabolism, F-54000 Nancy, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.metabol.2019.153992DOI Listing
December 2019

Mutations in MTHFR and POLG impaired activity of the mitochondrial respiratory chain in 46-year-old twins with spastic paraparesis.

J Hum Genet 2020 Jan 23;65(2):91-98. Epub 2019 Oct 23.

INSERM UMR_S 1256, NGERE-Nutrition, Genetics, and Environmental Risk Exposure and Reference Centre for Inherited Metabolic Diseases (ORPHA67872), University Hospital of Nancy and Faculty of Medicine of Nancy, University of Lorraine, Nancy, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s10038-019-0689-yDOI Listing
January 2020

IgE-mediated anaphylactic reaction against free synthetic folic acid and methyl folate.

J Allergy Clin Immunol Pract 2020 02 28;8(2):809-811. Epub 2019 Aug 28.

Inserm UMRS-1256, Faculté de Médecine, University of Lorraine and University Hospital Center (CHU) of Nancy, Nancy, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaip.2019.08.026DOI Listing
February 2020

Efficacy of low dose nitisinone in the management of alkaptonuria.

Mol Genet Metab 2019 07 19;127(3):184-190. Epub 2019 Jun 19.

Pediatric Unit, Reference center for Inborn Errors of Metabolism of Nancy, University Children's Hospital, CHU Brabois, Vandoeuvre les Nancy, France; INSERM UMRS 1256 NGERE, Nutrition, Genetics, and Environmental Risk Exposure, National Center of Inborn Errors of Metabolism, Faculty of Medicine of Nancy, University of Lorraine and University Regional Hospital Center of Nancy, Vandoeuvre-les-Nancy F-54000, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ymgme.2019.06.006DOI Listing
July 2019

Exome sequencing of cases with neural tube defects identifies candidate genes involved in one-carbon/vitamin B12 metabolisms and Sonic Hedgehog pathway.

Hum Genet 2019 Jul 28;138(7):703-713. Epub 2019 May 28.

INSERM U1256, NGERE-Nutrition, Genetics, and Environmental Risk Exposure, Faculty of Medicine of Nancy, University of Lorraine, 54000, Nancy, Vandoeuvre-lès-Nancy, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00439-019-02015-7DOI Listing
July 2019

Developmental Impairments in a Rat Model of Methyl Donor Deficiency: Effects of a Late Maternal Supplementation with Folic Acid.

Int J Mol Sci 2019 Feb 23;20(4). Epub 2019 Feb 23.

Université de Lorraine, Inserm U1256, NGERE, Faculté de Médecine, 9 avenue de la Forêt de Haye, F-54500 Vandoeuvre-lès-Nancy, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3390/ijms20040973DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6413039PMC
February 2019

Inherited disorders of cobalamin metabolism disrupt nucleocytoplasmic transport of mRNA through impaired methylation/phosphorylation of ELAVL1/HuR.

Nucleic Acids Res 2018 09;46(15):7844-7857

INSERM UMRS 954 NGERE - Nutrition, Genetics, and Environmental Risk Exposure and National Center of Inborn Errors of Metabolism, Faculty of Medicine of Nancy, University of Lorraine and University Regional Hospital Center of Nancy, Vandoeuvre-lès-Nancy, F-54000, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gky634DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6125644PMC
September 2018

MTHFR 677C → T genotype modulates the effect of a 5-year supplementation with B-vitamins on homocysteine concentration: The SU.FOL.OM3 randomized controlled trial.

PLoS One 2018 29;13(5):e0193352. Epub 2018 May 29.

Université Paris 13, Equipe de Recherche en Epidémiologie Nutritionnelle (EREN), Centre de Recherche en Epidémiologie et Statistiques, Inserm (U1153), Inra (U1125), Cnam, COMUE Sorbonne Paris Cité, Bobigny, France.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0193352PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5973566PMC
July 2018

Plasma mSEPT9: A Novel Circulating Cell-free DNA-Based Epigenetic Biomarker to Diagnose Hepatocellular Carcinoma.

EBioMedicine 2018 Apr 28;30:138-147. Epub 2018 Mar 28.

Department of Molecular Medicine and Personalized Therapeutics, Department of Biochemistry, Molecular Biology, Nutrition, and Metabolism, University Hospital of Nancy, F-54000, France; INSERM, U1256, NGERE - Nutrition, Genetics, and Environmental Risk Exposure, University of Lorraine, Nancy F-54000, France; Department of Hepatology and Gastroenterology, University Hospital of Nancy, Nancy F-54000, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ebiom.2018.03.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5952996PMC
April 2018

2009-2017 report on the attractiveness of laboratory medicine among young doctors.

Ann Biol Clin (Paris) 2018 Apr;76(2):125-130

Co-coordinateur du groupe de travail national de réforme du DES de biologie médicale, Laboratoire de biochimie - biologie moléculaire - nutrition - métabolisme, Centre de référence des maladies héréditaires du métabolisme et Inserm UMRS 954, CHRU de Nancy, Nancy, France, Président de la Commission nationale de la biologie médicale, Président de la section 44 du CNU, Président de la Commission nationale de biologie médicale.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1684/abc.2018.1323DOI Listing
April 2018

Extracellular vesicles as immune mediators in response to kidney injury.

Am J Physiol Renal Physiol 2018 01 30;314(1):F9-F21. Epub 2017 Aug 30.

INSERM U954, Nutrition Génétique et Exposition aux Risques Environnementaux, Medical Faculty, University of Lorraine, Lorraine, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/ajprenal.00336.2017DOI Listing
January 2018

Folate and vitamin B12 status is associated with insulin resistance and metabolic syndrome in morbid obesity.

Clin Nutr 2018 10 24;37(5):1700-1706. Epub 2017 Jul 24.

Inserm UMRS 954 N-GERE (Nutrition-Genetics-Environmental Risks), University de Lorraine, Faculty of Medicine, Nancy, France; Department of Digestive, Hepato-Biliary and Endocrine Surgery, Regional University Hospital of Nancy (CHRU Nancy), Nancy, France; Unité Multidisciplinaire de la chirurgie de l'obésité (UMCO), Regional University Hospital of Nancy (CHRU Nancy), Nancy, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.clnu.2017.07.008DOI Listing
October 2018

Vitamin B deficiency.

Nat Rev Dis Primers 2017 Jun 29;3:17040. Epub 2017 Jun 29.

Diabetes Unit, King Edward Memorial Hospital, Pune, Maharashtra, India.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nrdp.2017.40DOI Listing
June 2017

Genetic Predictors of Drug Hypersensitivity.

Curr Pharm Des 2016 ;22(45):6725-6733

Faculte de Medecine, Batiment C 2eme etage, 9 avenue de la Foret de Haye - B.P. 184, 54505 Vandoeuvre- les-Nancy CEDEX, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/1381612822666160927114941DOI Listing
December 2017

Methionine synthase and methionine synthase reductase interact with MMACHC and with MMADHC.

Biochim Biophys Acta Mol Basis Dis 2017 Jan 19;1863(1):103-112. Epub 2016 Oct 19.

UMR_S UL-Inserm U954 Nutrition-Genetics-Environmental Risk Exposure and Reference Centre of Inborn Metabolism Diseases, Medical Faculty of Nancy University and University Hospital Centre, Nancy, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbadis.2016.10.016DOI Listing
January 2017

The importance of gene-environment interactions in human obesity.

Clin Sci (Lond) 2016 09;130(18):1571-97

Department of Clinical Epidemiology and Biostatistics, McMaster University, Hamilton, Ontario, Canada L8N 3Z5 Inserm U-954, Faculté de Médecine, University of Lorraine and University Hospital Center of Nancy, Nancy 54052, France Department of Pathology and Molecular Medicine, McMaster University, Hamilton, Ontario, Canada L8N 3Z5

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1042/CS20160221DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6381863PMC
September 2016

Methyl donor deficiency impairs bone development via peroxisome proliferator-activated receptor-γ coactivator-1α-dependent vitamin D receptor pathway.

FASEB J 2016 10 19;30(10):3598-3612. Epub 2016 Jul 19.

INSERM U954, Nutrition Génétique et Exposition aux Risques Environnementaux, Faculty of Medicine, University of Lorraine, Vandœuvre les Nancy, France;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1096/fj.201600332RDOI Listing
October 2016

One carbon metabolism, a complex metabolic network involved in pathomechanisms of inherited disorders, birth defects and age-related pathologies.

Biochimie 2016 Jul 15;126:1-2. Epub 2016 May 15.

Inserm UMRS 954 Nutrition-Genetics-Environmental Risk Exposure and Reference Centre of Inborn Metabolism Diseases, Medical Faculty of Nancy University and University Hospital Centre, Nancy, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.biochi.2016.05.008DOI Listing
July 2016

Genetic animal models to decipher the pathogenic effects of vitamin B12 and folate deficiency.

Biochimie 2016 Jul 10;126:43-51. Epub 2016 May 10.

UMR 964 INSERM-Université de Lorraine, NGERE, Medical Faculty and University Hospital Center, Vandoeuvre les Nancy, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.biochi.2016.05.007DOI Listing
July 2016

One carbon metabolism and bone homeostasis and remodeling: A review of experimental research and population studies.

Biochimie 2016 Jul 13;126:115-23. Epub 2016 Apr 13.

INSERM U954, Nutrition Génétique et Exposition aux Risques Environnementaux, Medical Faculty, University of Lorraine and Regional University Hospital Center of Nancy, Vandœuvre les Nancy, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.biochi.2016.04.009DOI Listing
July 2016

Editorial.

Biochimie 2016 Jun 9;125:232-3. Epub 2016 Apr 9.

University of Lorraine and University Regional Hospital Centre of Nancy, Nancy, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.biochi.2016.04.006DOI Listing
June 2016

NOD2 gene variant is a risk factor for postoperative complications in patients with Crohn's disease: A genetic association study.

Surgery 2016 07 2;160(1):74-80. Epub 2016 Mar 2.

INSERM U954, Nutrition-Génétique et Exposition aux risques environnementaux, Faculté de Médecine, Université de Lorraine, Vandoeuvre-les-Nancy, France; Department of Hepatogastroenterology, University Hospital of Nancy-Brabois, Vandoeuvre-les-Nancy, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.surg.2016.01.013DOI Listing
July 2016

Mutation Update and Review of Severe Methylenetetrahydrofolate Reductase Deficiency.

Hum Mutat 2016 May 18;37(5):427-38. Epub 2016 Mar 18.

Division of Metabolism and Children's Research Center, University Children's Hospital, Zürich, CH-8032, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/humu.22970DOI Listing
May 2016

Predictors of High Motivation Score for Performing Research Initiation Fellowship, Master 1, Research Master 2, and PhD Curricula During Medical Studies: A Strobe-Compliant Article.

Medicine (Baltimore) 2016 Feb;95(5):e2633

From the University of Poitiers, UFR Médecine Pharmacie (EF, SH, RM, PR); Department of Endocrinology, University Hospital of Poitiers, Poitiers, (EF, SH, RM); Department of Molecular Medicine and Personalized Therapeutics, Department of Biochemistry, Molecular Biology, Nutrition, and Metabolism, University Hospital of Nancy, Vandoeuvre-lès-Nancy, France (AO, J-LG); INSERM, U954, NGERE - Nutrition, Genetics, and Environmental Risk Exposure, Faculty of Medicine of Nancy, University of Lorraine, Vandoeuvre-lès-Nancy, France (AO, J-LG); Medical Simulation Centre, Faculty of Medicine of Nice, University of Nice-Sophia-Antipolis, Nice (J-PF); Direction du Numérique, Faculty of Medicine of Nancy, University of Lorraine, Vandoeuvre-lès-Nancy (AA); Department of Internal Medicine and Infectious Diseases, University Hospital of Poitiers, University of Poitiers, Poitiers (PR); Department of Neuroradiology, University Hospital of Nancy, Nancy, France (MB); and Faculty of Medicine of Nancy, University of Lorraine, Vandoeuvre-lès-Nancy, France ; University Centre for Education by Medical Simulation (CUESIM) - The Virtual Hospital of Lorraine of the Faculty of Medicine of Nancy; INSERM U947, IADI - Diagnostic and Interventional Adaptive Imaging, Vandoeuvre-lès-Nancy, France (MB).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MD.0000000000002633DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4748895PMC
February 2016

Diagnostic Accuracy of Procalcitonin for Predicting Blood Culture Results in Patients With Suspected Bloodstream Infection: An Observational Study of 35,343 Consecutive Patients (A STROBE-Compliant Article).

Medicine (Baltimore) 2015 Nov;94(44):e1774

From the Department of Molecular Medicine and Personalized Therapeutics, Department of Biochemistry, Molecular Biology, Nutrition, and Metabolism, University Hospital of Nancy (AO, PF-T, IA-G, FN, MG, J-LG); INSERM, U954, NGERE - Nutrition, Genetics, and Environmental Risk Exposure, Faculty of Medicine of Nancy, University of Lorraine (AO, IA-G, FN, J-LG); Department of Bacteriology, University Hospital of Nancy (JF, NA, AL), and EA7300, Stress Immunity Pathogens Laboratory, Faculty of Medicine of Nancy, University of Lorraine, Vandoeuvre-lès-Nancy, France (JF, NA, AL).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MD.0000000000001774DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4915876PMC
November 2015

CARD8 gene variant is a risk factor for recurrent surgery in patients with Crohn's disease.

Dig Liver Dis 2015 Nov 29;47(11):938-42. Epub 2015 Jul 29.

INSERM U954, Nutrition-Génétique et Exposition aux risques environnementaux, Faculté de Médecine, Université de Lorraine, Vandoeuvre-les-Nancy, France; Department of Gastroenterology, University Hospital of Nancy-Brabois, Vandoeuvre-les-Nancy, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.dld.2015.07.013DOI Listing
November 2015

IgE antibodies and skin tests in immediate hypersensitivity reactions to infliximab in inflammatory bowel disease: impact on infliximab retreatment.

Eur J Gastroenterol Hepatol 2015 Oct;27(10):1200-8

aDepartment of Dermatology and Allergy bInserm U954, Department of Hepato-Gastroenterology cInserm U954, Department of Pediatrics dInserm U-954, NGERE - Nutrition, Genetics, and Environmental Risk Exposure, Faculty of Medicine, University Hospital of Nancy, Lorraine University, Vandoeuvre les Nancy, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MEG.0000000000000436DOI Listing
October 2015

Impact of immunosuppressive therapy on hepatitis B vaccination in inflammatory bowel diseases.

Eur J Gastroenterol Hepatol 2015 Aug;27(8):877-81

aInserm U954 and Department of Hepato-Gastroenterology, University Hospital of Nancy bESPRI Unit, Clinical epidemiology, CHU de Nancy, Lorraine University, Vandoeuvre-lès-Nancy, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MEG.0000000000000370DOI Listing
August 2015

Exome-Wide Association Study Identifies New Low-Frequency and Rare UGT1A1 Coding Variants and UGT1A6 Coding Variants Influencing Serum Bilirubin in Elderly Subjects: A Strobe Compliant Article.

Medicine (Baltimore) 2015 Jun;94(22):e925

From the Inserm, NGERE - Nutrition, Genetics, and Environmental Risk Exposure (AO, R-MG-R, CC, PR, J-PB, J-LG); Faculty of Medicine of Nancy, University of Lorraine (AO, R-MG-R, CC, J-PB, J-LG); University Hospital of Nancy, Department of Molecular Medicine and Personalized Therapeutics, Department of Biochemistry, Molecular Biology, Nutrition, and Metabolism (AO, R-MG-R, CC, TJ, J-LG); Reference Centre for Inherited Metabolic Diseases (ORPHA67872), Vandoeuvre-lès-Nancy, France (AO, R-MG-R, CC, TJ, J-LG); IRCCS, Oasi Maria SS-Institute for Research on Mental Retardation, Troina (PB, GA, RS, AR, ME); Department of Internal Medicine and Geriatrics, UCSC, CI Columbus, Roma, Italy (AR); and Department of Gastroenterology and Hepatology, University Hospital of Nancy, Vandoeuvre-lès-Nancy, France (J-PB).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MD.0000000000000925DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4616369PMC
June 2015

Folate- and vitamin B12-deficient diet during gestation and lactation alters cerebellar synapsin expression via impaired influence of estrogen nuclear receptor α.

FASEB J 2015 Sep 27;29(9):3713-25. Epub 2015 May 27.

*Institut National de la Santé et de la Recherche Médicale, Unité 954, Nutrition-Genetics and Environmental Exposure, Medical Faculty and University Hospital Center, Nancy University, Vandoeuvre lès Nancy, France; Human Nutrition Unit, Unité Mixte de Recherche 1019 Institut National de la Recherche Agronomique/University of Auvergne, Institut National de la Recherche Agronomique Centre of Theix, Saint-Genès Champanelle, France; and Istituto di Ricovero e Cura a Carattere Scientifico, Oasi Maria Santissima-Institute for Research on Mental Retardation and Brain Aging, Troina, Italy

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1096/fj.14-264267DOI Listing
September 2015

Methyl(R217)HuR and MCM6 are inversely correlated and are prognostic markers in non small cell lung carcinoma.

Lung Cancer 2015 Aug 16;89(2):189-96. Epub 2015 May 16.

Department of Pathology, CHU Nancy, France; INSERM U954, Faculty of Medicine, Université de Lorraine, Nancy, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.lungcan.2015.05.008DOI Listing
August 2015

Information-seeking behavior during residency is associated with quality of theoretical learning, academic career achievements, and evidence-based medical practice: a strobe-compliant article.

Medicine (Baltimore) 2015 Feb;94(6):e535

From the Faculty of Medicine of Nancy, University of Lorraine, Department of Biochemistry, Molecular Biology, Nutrition, and Metabolism, University Hospital of Nancy; and Inserm U954, NGERE-Nutrition, Genetics, and Environmental Risk Exposure, Vandoeuvre-lès-Nancy (AO, JLG); Medical Simulation Centre, Faculty of Medicine of Nice, University of Nice-Sophia-Antipolis, Nice (JPF); Faculty of Medicine of Nancy, University of Lorraine; University Centre for Education by Medical Simulation (CUESIM)-The Virtual Hospital of Lorraine of the Faculty of Medicine of Nancy; Inserm U947, IADI-Diagnostic and Interventional Adaptive Imaging; and Department of Neuroradiology, University Hospital of Nancy, Nancy (MB), France.

View Article

Download full-text PDF

Source
https://insights.ovid.com/crossref?an=00005792-201502020-000
Publisher Site
http://dx.doi.org/10.1097/MD.0000000000000535DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4602751PMC
February 2015

Methyl-deficient diet promotes colitis and SIRT1-mediated endoplasmic reticulum stress.

Gut 2016 Apr 20;65(4):595-606. Epub 2015 Jan 20.

INSERM U954, Faculté de Médecine, Nutrition Génétique et exposition aux risques environnementaux, Université de Lorraine 54 511, Vandœuvre-Lès-Nancy cedex, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1136/gutjnl-2014-307030DOI Listing
April 2016

Identification of master genes involved in liver key functions through transcriptomics and epigenomics of methyl donor deficiency in rat: relevance to nonalcoholic liver disease.

Mol Nutr Food Res 2015 Feb 9;59(2):293-302. Epub 2014 Dec 9.

Institut National de la Santé et de la Recherche Médicale (INSERM), Faculté de Médecine, Vandœuvre-lès-Nancy, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/mnfr.201400483DOI Listing
February 2015

Early methyl donor deficiency alters cAMP signaling pathway and neurosteroidogenesis in the cerebellum of female rat pups.

Am J Physiol Endocrinol Metab 2014 Dec 7;307(11):E1009-19. Epub 2014 Oct 7.

Institut National de la Sante et de la Recherche Medicale, U-954, Nutrition-Génétique et Exposition Aux Risques Environnementaux, Faculté de Médecine, Université de Lorraine, Vandoeuvre les Nancy, France

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/ajpendo.00364.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254983PMC
December 2014

HLA-DRA variants predict penicillin allergy in genome-wide fine-mapping genotyping.

J Allergy Clin Immunol 2015 Jan 12;135(1):253-9. Epub 2014 Sep 12.

Inserm U-954, Faculté de Médecine, University of Lorraine and University Hospital Center (CHU) of Nancy, Nancy, France; Allergy Service, Carlos Haya Hospital (IBIMA-Hospital Regional Universitario de Malaga), Malaga, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jaci.2014.07.047DOI Listing
January 2015

[Vitamin B12 and related genetic disorders].

Bull Acad Natl Med 2014 Jun;198(6):1141-56

View Article

Download full-text PDF

Source
June 2014

CARM1 and PRMT1 are dysregulated in lung cancer without hierarchical features.

Biochimie 2014 Feb 6;97:210-8. Epub 2013 Nov 6.

INSERM NGERE UMR 954, Vandoeuvre F-54500, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.biochi.2013.10.021DOI Listing
February 2014

Nutritional models of foetal programming and nutrigenomic and epigenomic dysregulations of fatty acid metabolism in the liver and heart.

Pflugers Arch 2014 May 3;466(5):833-50. Epub 2013 Sep 3.

Inserm U954, Nutrition-Genetics-Environmental Risk Exposure (N-GERE), University of Lorraine and University Hospital Center of Nancy, BP 184, 54511, Vandœuvre-lès-Nancy, France,

View Article

Download full-text PDF

Source
http://link.springer.com/10.1007/s00424-013-1339-4
Publisher Site
http://dx.doi.org/10.1007/s00424-013-1339-4DOI Listing
May 2014

Interaction between methionine synthase isoforms and MMACHC: characterization in cblG-variant, cblG and cblC inherited causes of megaloblastic anaemia.

Hum Mol Genet 2013 Nov 3;22(22):4591-601. Epub 2013 Jul 3.

Inserm U954 Nutrition-Genetics-Environmental Risk Exposure and Reference Centre of Inborn Metabolism Diseases, Medical Faculty of Nancy University and University Hospital Centre, Nancy, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/hmg/ddt308DOI Listing
November 2013

Microscopic features for initial diagnosis and disease activity evaluation in inflammatory bowel disease.

Inflamm Bowel Dis 2013 Jul;19(8):1745-52

Inserm U954, Medical Faculty and CHU of Nancy, Nancy-Université, Nancy, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/MIB.0b013e318281f2e8DOI Listing
July 2013