Jean-Jacques Schott

Jean-Jacques Schott

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Jean-Jacques Schott

Jean-Jacques Schott

Publications by authors named "Jean-Jacques Schott"

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Familial bicuspid aortic valve disease: should we look more closely at the valve?

Heart 2019 04 12;105(8):584-586. Epub 2018 Dec 12.

l'institut du thorax, INSERM, CNRS, CHU Nantes, Univ Nantes, Nantes, France.

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http://dx.doi.org/10.1136/heartjnl-2018-314063DOI Listing
April 2019

Genetics of syndromic and non-syndromic mitral valve prolapse.

Heart 2018 06 19;104(12):978-984. Epub 2018 Jan 19.

l'institut du thorax, INSERM, CNRS, Université de Nantes, Nantes, France.

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http://dx.doi.org/10.1136/heartjnl-2017-312420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6168077PMC
June 2018

Value of the sodium-channel blocker challenge in Brugada syndrome.

Int J Cardiol 2017 Oct 4;245:178-180. Epub 2017 Aug 4.

CHU Nantes, L'institut du thorax, Service de Cardiologie, Nantes F-44000, France; INSERM, CNRS, UNIV Nantes, L'institut du thorax, Nantes F-44000, France. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2017.05.099DOI Listing
October 2017

Clinical Yield of Familial Screening After Sudden Death in Young Subjects: The French Experience.

Circ Arrhythm Electrophysiol 2017 Sep;10(9)

From the l'institut du thorax, INSERM, CNRS, UNIV Nantes, CHU Nantes (P.Q., F.K., A.T., B.G., R.R., J.B., J.-J.S., V.P., J.B.G.); Service de cardiologie, CHU de Rennes, (P.M.); Service de cardiologie, CHU de Brest (J.M.); Service de cardiologie, CHU de Tours (D.B.); and Service de cardiologie, Institut Lyric, CHU de Bordeaux, France (F.S.).

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http://dx.doi.org/10.1161/CIRCEP.117.005236DOI Listing
September 2017

The alternatively spliced LRRFIP1 Isoform-1 is a key regulator of the Wnt/β-catenin transcription pathway.

Biochim Biophys Acta Mol Cell Res 2017 Jul 18;1864(7):1142-1152. Epub 2017 Mar 18.

l'institut du thorax, INSERM, CNRS, UNIV Nantes, Nantes, France. Electronic address:

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http://dx.doi.org/10.1016/j.bbamcr.2017.03.008DOI Listing
July 2017

TRPM4 non-selective cation channel variants in long QT syndrome.

BMC Med Genet 2017 03 18;18(1):31. Epub 2017 Mar 18.

Laboratoire Cardiogénétique, Institut de Biologie et Chimie des Protéines, INSERM UMR 5305, Université Lyon 1, Lyon, France.

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http://dx.doi.org/10.1186/s12881-017-0397-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5357330PMC
March 2017

Identification of novel APOB mutations by targeted next-generation sequencing for the molecular diagnosis of familial hypobetalipoproteinemia.

Atherosclerosis 2016 07 11;250:52-6. Epub 2016 Apr 11.

INSERM, UMR1087, l'institut du thorax, Nantes, F-44000, France; CNRS, UMR 6291, Nantes, F-44000, France; Université de Nantes, Nantes, F-44000, France; CHU Nantes, l'institut du Thorax, Nantes, F-44000, France; CIC Thorax, CHU Nantes, l'institut du Thorax, Nantes, F-44000, France. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2016.04.010DOI Listing
July 2016

The Brugada Syndrome: A Rare Arrhythmia Disorder with Complex Inheritance.

Front Cardiovasc Med 2016 25;3. Epub 2016 Apr 25.

Service de Cardiologie, Centre Hospitalier Universitaire (CHU) de Nantes, l'institut du thorax, Nantes, France; Institut National de la Santé et de la Recherche Médicale (INSERM) Unité Mixte de Recherche (UMR) 1087, l'institut du thorax, Nantes, France; Centre National de la Recherche Scientifique (CNRS) UMR 6291, l'institut du thorax, Nantes, France; l'institut du thorax, Université de Nantes, Nantes, France.

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http://dx.doi.org/10.3389/fcvm.2016.00009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842929PMC
May 2016

Targeted resequencing identifies TRPM4 as a major gene predisposing to progressive familial heart block type I.

Int J Cardiol 2016 Mar 11;207:349-58. Epub 2016 Jan 11.

Institut National de la Santé et de la Recherche Médicale (INSERM) Unité Mixte de Recherche (UMR) 1087, l'institut du thorax, Nantes, France; Centre National de la Recherche Scientifique (CNRS) UMR 6291, l'institut du thorax, Nantes, France; Université de Nantes, l'institut du thorax, Nantes, France; Centre Hospitalier Universitaire (CHU) de Nantes, l'institut du thorax, Service de Cardiologie, Nantes, France. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2016.01.052DOI Listing
March 2016

MVP-Associated Filamin A Mutations Affect FlnA-PTPN12 (PTP-PEST) Interactions.

J Cardiovasc Dev Dis 2015 Sep;2(3):233-247

Institut du thorax, Inserm UMR 1087, CNRS UMR 6291, 8 Quai Moncousu, Nantes F-44007, France; (D.D.); (P.L.); (L.B.); (T.L.T.); (J.-J.S.).

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http://dx.doi.org/10.3390/jcdd2030233DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654411PMC
September 2015

Fine-scale human genetic structure in Western France.

Eur J Hum Genet 2015 Jun 3;23(6):831-6. Epub 2014 Sep 3.

1] INSERM UMR 1087, Nantes, France [2] CNRS, UMR 6291 institut du thorax, Nantes, France [3] Université de Nantes, Nantes, France [4] CHU Nantes, l'institut du thorax, Service de Cardiologie, Nantes, France.

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http://dx.doi.org/10.1038/ejhg.2014.175DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4795055PMC
June 2015

Analysis for Genetic Modifiers of Disease Severity in Patients With Long-QT Syndrome Type 2.

Circ Cardiovasc Genet 2015 Jun 3;8(3):447-456. Epub 2015 Mar 3.

Department of Clinical and Experimental Cardiology (I.C.R.M.K., P.G.P., J.B., T.T.K., A.A.M.W., C.R.B.), Department of Clinical Epidemiology, Biostatistics and Bioinformatics (I.C.R.M.K., M.W.T.T.), and Department of Clinical Genetics (N.H.), Academic Medical Center, Amsterdam, the Netherlands; ICIN (Netherlands Heart Institute) (J.B., A.A.M.W., C.R.B.), Utrecht, the Netherlands; Institut National de la Santé et de la Recherche Médicale (INSERM) Unité Mixte de Recherche (UMR) 1087, L'Institut du Thorax, Nantes, France (J.B., J.-J.S.); Centre National de la Recherche Scientifique (CNRS) UMR 6291, Nantes, France (J.B., J.-J.S.); Université de Nantes, Nantes, France (J.B., J.-J.S.); Department of Medicine I, University Hospital Munich, Campus Grosshadern and Innenstadt, Ludwig-Maximilians University, Munich, Germany (M.F.S., B.M.B., S.K.); German Center for Cardiovascular Research (DZHK), Munich Heart Alliance, Munich, Germany (S.K.T.M.); Institute for Genetics of Heart Diseases, Department of Cardiovascular Medicine, University Hospital Münster, Münster, Germany (S.Z., A.H., B.S., E.S.-B.); Interdisciplinary Centre for Clinical Research (IZKF) of the University of Münster, Münster, Germany (S.Z., A.H., B.S., E.S.-B.); Institute of Bioinformatics and Systems Biology (A.P.), and Institute of Human Genetics (A.P., P.L., T.M.), Helmholtz Zentrum München, Neuherberg, Germany; Institute of Human Genetics, Technische Universität München, Munich, Germany (A.P., P.L., T.M.); Department of Medicine (R.J.M., N.H.B.), Department of Molecular and Cellular Pharmacology (R.J.M., N.H.B.), and Hussmann Institute of Human Genomics (R.J.M., N.H.B.), University of Miami Miller School of Medicine, FL; Department of Medicine and Pharmacology, Vanderbilt University School of Medicine, Nashville, TN (D.M.R.); Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders, Jeddah, Kingdom of Saudi Arabia (A.A.M.W.); and Centre Hospitalier Universitaire (CHU) Nantes, L'Institut du Thorax, Service de Cardiologie, Nantes, France (J.-J.S.).

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http://dx.doi.org/10.1161/CIRCGENETICS.114.000785DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4770255PMC
June 2015

Myotonic dystrophy type 1 mimics and exacerbates Brugada phenotype induced by Nav1.5 sodium channel loss-of-function mutation.

Heart Rhythm 2014 Aug 21;11(8):1393-400. Epub 2014 Apr 21.

Institut de Physiologie et de Biologie Cellulaire, ERL CNRS 7368, Université de Poitiers, France.

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http://dx.doi.org/10.1016/j.hrthm.2014.04.026DOI Listing
August 2014

Genetic association study of QT interval highlights role for calcium signaling pathways in myocardial repolarization.

Authors:
Dan E Arking Sara L Pulit Lia Crotti Pim van der Harst Patricia B Munroe Tamara T Koopmann Nona Sotoodehnia Elizabeth J Rossin Michael Morley Xinchen Wang Andrew D Johnson Alicia Lundby Daníel F Gudbjartsson Peter A Noseworthy Mark Eijgelsheim Yuki Bradford Kirill V Tarasov Marcus Dörr Martina Müller-Nurasyid Annukka M Lahtinen Ilja M Nolte Albert Vernon Smith Joshua C Bis Aaron Isaacs Stephen J Newhouse Daniel S Evans Wendy S Post Daryl Waggott Leo-Pekka Lyytikäinen Andrew A Hicks Lewin Eisele David Ellinghaus Caroline Hayward Pau Navarro Sheila Ulivi Toshiko Tanaka David J Tester Stéphanie Chatel Stefan Gustafsson Meena Kumari Richard W Morris Åsa T Naluai Sandosh Padmanabhan Alexander Kluttig Bernhard Strohmer Andrie G Panayiotou Maria Torres Michael Knoflach Jaroslav A Hubacek Kamil Slowikowski Soumya Raychaudhuri Runjun D Kumar Tamara B Harris Lenore J Launer Alan R Shuldiner Alvaro Alonso Joel S Bader Georg Ehret Hailiang Huang W H Linda Kao James B Strait Peter W Macfarlane Morris Brown Mark J Caulfield Nilesh J Samani Florian Kronenberg Johann Willeit J Gustav Smith Karin H Greiser Henriette Meyer Zu Schwabedissen Karl Werdan Massimo Carella Leopoldo Zelante Susan R Heckbert Bruce M Psaty Jerome I Rotter Ivana Kolcic Ozren Polašek Alan F Wright Maura Griffin Mark J Daly David O Arnar Hilma Hólm Unnur Thorsteinsdottir Joshua C Denny Dan M Roden Rebecca L Zuvich Valur Emilsson Andrew S Plump Martin G Larson Christopher J O'Donnell Xiaoyan Yin Marco Bobbo Adamo P D'Adamo Annamaria Iorio Gianfranco Sinagra Angel Carracedo Steven R Cummings Michael A Nalls Antti Jula Kimmo K Kontula Annukka Marjamaa Lasse Oikarinen Markus Perola Kimmo Porthan Raimund Erbel Per Hoffmann Karl-Heinz Jöckel Hagen Kälsch Markus M Nöthen Marcel den Hoed Ruth J F Loos Dag S Thelle Christian Gieger Thomas Meitinger Siegfried Perz Annette Peters Hanna Prucha Moritz F Sinner Melanie Waldenberger Rudolf A de Boer Lude Franke Pieter A van der Vleuten Britt Maria Beckmann Eimo Martens Abdennasser Bardai Nynke Hofman Arthur A M Wilde Elijah R Behr Chrysoula Dalageorgou John R Giudicessi Argelia Medeiros-Domingo Julien Barc Florence Kyndt Vincent Probst Alice Ghidoni Roberto Insolia Robert M Hamilton Stephen W Scherer Jeffrey Brandimarto Kenneth Margulies Christine E Moravec Fabiola del Greco M Christian Fuchsberger Jeffrey R O'Connell Wai K Lee Graham C M Watt Harry Campbell Sarah H Wild Nour E El Mokhtari Norbert Frey Folkert W Asselbergs Irene Mateo Leach Gerjan Navis Maarten P van den Berg Dirk J van Veldhuisen Manolis Kellis Bouwe P Krijthe Oscar H Franco Albert Hofman Jan A Kors André G Uitterlinden Jacqueline C M Witteman Lyudmyla Kedenko Claudia Lamina Ben A Oostra Gonçalo R Abecasis Edward G Lakatta Antonella Mulas Marco Orrú David Schlessinger Manuela Uda Marcello R P Markus Uwe Völker Harold Snieder Timothy D Spector Johan Ärnlöv Lars Lind Johan Sundström Ann-Christine Syvänen Mika Kivimaki Mika Kähönen Nina Mononen Olli T Raitakari Jorma S Viikari Vera Adamkova Stefan Kiechl Maria Brion Andrew N Nicolaides Bernhard Paulweber Johannes Haerting Anna F Dominiczak Fredrik Nyberg Peter H Whincup Aroon D Hingorani Jean-Jacques Schott Connie R Bezzina Erik Ingelsson Luigi Ferrucci Paolo Gasparini James F Wilson Igor Rudan Andre Franke Thomas W Mühleisen Peter P Pramstaller Terho J Lehtimäki Andrew D Paterson Afshin Parsa Yongmei Liu Cornelia M van Duijn David S Siscovick Vilmundur Gudnason Yalda Jamshidi Veikko Salomaa Stephan B Felix Serena Sanna Marylyn D Ritchie Bruno H Stricker Kari Stefansson Laurie A Boyer Thomas P Cappola Jesper V Olsen Kasper Lage Peter J Schwartz Stefan Kääb Aravinda Chakravarti Michael J Ackerman Arne Pfeufer Paul I W de Bakker Christopher Newton-Cheh

Nat Genet 2014 Aug 22;46(8):826-36. Epub 2014 Jun 22.

1] Center for Human Genetic Research, Massachusetts General Hospital, Boston, Massachusetts, USA. [2] Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, Massachusetts, USA. [3] Harvard Medical School, Boston, Massachusetts, USA. [4] Cardiovascular Research Center, Massachusetts General Hospital, Boston, Massachusetts, USA. [5].

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http://dx.doi.org/10.1038/ng.3014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4124521PMC
August 2014

Common variants at SCN5A-SCN10A and HEY2 are associated with Brugada syndrome, a rare disease with high risk of sudden cardiac death.

Nat Genet 2013 Sep 21;45(9):1044-9. Epub 2013 Jul 21.

Department of Clinical and Experimental Cardiology, Heart Failure Research Center, Academic Medical Center, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/ng.2712DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3869788PMC
September 2013

Developmental basis for filamin-A-associated myxomatous mitral valve disease.

Cardiovasc Res 2012 Oct 25;96(1):109-19. Epub 2012 Jul 25.

Department of Regenerative Medicine and Cell Biology, School of Medicine, Cardiovascular Developmental Biology Center, Children's Research Institute, Medical University of South Carolina, 171 Ashley Avenue, Charleston, SC 29425, USA.

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http://dx.doi.org/10.1093/cvr/cvs238DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3444235PMC
October 2012

Early Repolarization Disease.

Card Electrophysiol Clin 2010 Dec;2(4):559-569

Hôpital Cardiologique du Haut-Lévêque, Université Bordeaux II, 33604 Bordeaux, France.

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http://dx.doi.org/10.1016/j.ccep.2010.09.002DOI Listing
December 2010

Exon organization and novel alternative splicing of the human ANK2 gene: implications for cardiac function and human cardiac disease.

J Mol Cell Cardiol 2008 Dec 27;45(6):724-34. Epub 2008 Aug 27.

Department of Internal Medicine, Division of Cardiovascular Medicine, University of Iowa Carver College of Medicine, Iowa City, IA 52242, USA.

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http://dx.doi.org/10.1016/j.yjmcc.2008.08.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2630508PMC
December 2008

14-3-3 is a regulator of the cardiac voltage-gated sodium channel Nav1.5.

Circ Res 2006 Jun 25;98(12):1538-46. Epub 2006 May 25.

Inserm UMR533, Université de Nantes, Nantes Atlantique Universités, l'Institut du thorax, Faculté de Médecine, France.

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http://dx.doi.org/10.1161/01.RES.0000229244.97497.2cDOI Listing
June 2006

Monomorphic ventricular tachycardia due to Brugada syndrome successfully treated by hydroquinidine therapy in a 3-year-old child.

J Cardiovasc Electrophysiol 2006 Jan;17(1):97-100

Department of Cardiology and Unité INSERM U533, Institut du thorax, CHU de Nantes, Nantes, France.

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http://dx.doi.org/10.1111/j.1540-8167.2005.00329.xDOI Listing
January 2006

A common antitussive drug, clobutinol, precipitates the long QT syndrome 2.

Mol Pharmacol 2004 Nov 27;66(5):1093-102. Epub 2004 Jul 27.

l'Institut du thorax, Institut National de la Sante et de la Recherche Medicale U533, Nantes, France.

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http://dx.doi.org/10.1124/mol.104.001065DOI Listing
November 2004

Cardiac retention of [11C]HED in genotyped long QT patients: a potential amplifier role for severity of the disease.

Am J Physiol Heart Circ Physiol 2003 Sep 29;285(3):H1286-93. Epub 2003 May 29.

Centre d'Exploration et de Recherche Médicales par Emission de Positons, 69003 Lyon, France.

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http://dx.doi.org/10.1152/ajpheart.00276.2003DOI Listing
September 2003

Ankyrin-B mutation causes type 4 long-QT cardiac arrhythmia and sudden cardiac death.

Nature 2003 Feb;421(6923):634-9

Howard Hughes Medical Institute and Departments of Cell Biology, Biochemistry, and Neuroscience, Duke University Medical Center, Durham, North Carolina 27710, USA.

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http://dx.doi.org/10.1038/nature01335DOI Listing
February 2003

Novel brugada SCN5A mutation leading to ST segment elevation in the inferior or the right precordial leads.

J Cardiovasc Electrophysiol 2003 Feb;14(2):200-3

Institut National de la Santé et de la Recherche Médicale (INSERM) U533, Faculté de Médecine, the Cardiology Department, Hôpital G&R Laennec, Nantes, France.

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http://dx.doi.org/10.1046/j.1540-8167.2003.02382.xDOI Listing
February 2003