Publications by authors named "Jean-Francois Emile"

100Publications

Multispectral imaging detects gastritis consistently in mouse model and in humans.

Sci Rep 2020 11 18;10(1):20047. Epub 2020 Nov 18.

Department of Gastroenterology, Université Paris Saclay/UVSQ, INSERM, Infection and Inflammation, UMR 1173, AP-HP, Hôpital Ambroise Paré, 9 avenue Charles de Gaulle, 92100, Boulogne Billancourt, France.

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http://dx.doi.org/10.1038/s41598-020-77145-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7674504PMC
November 2020

Central nervous system involvement in Erdheim-Chester disease: An observational cohort study.

Neurology 2020 11 4;95(20):e2746-e2754. Epub 2020 Sep 4.

From Service de Médecine Interne 2, Centre National de Référence Maladies Systémiques Rares et Histiocytoses (F.C.A., Z.A., J.H.), Service de Neuroradiologie (D.G., B.L.-Y.), Service d'Anatomopathologie (F.C.), Service de Médecine Nucléaire (P.M.), Service de Neuropathologie (D.S.), Hôpital Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris, Sorbonne Université; Service de Neurologie 2-Mazarin (A.I., K.H.-Z.), Inserm, CNRS, UMR S 1127, Institut du Cerveau et de la Moelle Épinière, ICM, AP-HP, Hôpitaux Universitaires La Pitié Salpêtrière-Charles Foix, Sorbonne Université, Paris; Département de Pathologie (J.-F.E.), EA4340, Université Versailles-Saint Quentin, Assistance Publique Hôpitaux de Paris, Hôpital Ambroise Paré, Boulogne; and Service d'Hématologie Pédiatrique, Centre de Référence National Histiocytoses (J.D.), Hôpital Trousseau, Sorbonne Université, Paris, France.

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http://dx.doi.org/10.1212/WNL.0000000000010748DOI Listing
November 2020

Immune phenotyping of Erdheim-Chester disease through mass cytometry highlights decreased proportion of non-classical monocytes and increased proportion of Th17 cells.

Ann Rheum Dis 2020 11 18;79(11):1522-1524. Epub 2020 May 18.

Laboratory of molecular mechanisms of hematologic disorders and therapeutic implications, Imagine Institute, INSERM UMR1163, Paris, France.

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http://dx.doi.org/10.1136/annrheumdis-2020-217316DOI Listing
November 2020

Fatal Cytomegalovirus Infection in an Adult with Inherited NOS2 Deficiency.

N Engl J Med 2020 01;382(5):437-445

From St. Giles Laboratory of Human Genetics of Infectious Diseases, Rockefeller Branch, Rockefeller University (S.B.D., D.H., N.H., S.B., F.R., B.B., R.F., E.J., J.B., L.A., S.B.-D., J.-L.C.), the Department of Microbiology and Immunology, Weill Cornell Medicine (R.B., C.N.), and Howard Hughes Medical Institute (J.-L.C.) - all in New York; the Pediatric Respiratory Diseases Research Center (D.M., S.A.M.), the Department of Clinical Immunology and Infectious Diseases (D.M., N. Mansouri), and the Clinical Tuberculosis and Epidemiology Research Center (D.M., M.M.), National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti University of Medical Sciences, Tehran, Iran; the Laboratory of Human Genetics of Infectious Diseases, Necker Branch, INSERM Unité 1163 (A.-L.N., L.L.-D., E.J., J.B., L.A., S.B.-D., V.B., J.-L.C.), Paris University, Imagine Institute (A.-L.N., L.L.-D., E.J., J.B., L.A., S.B.-D., V.B., J.-L.C.), and the Study Center for Primary Immunodeficiencies, Assistance Publique-Hôpitaux de Paris (AP-HP) (J.B.), and the Pediatric Immunology-Hematology Unit (J.-L.C.), Necker Hospital for Sick Children, Paris, and the Department of Pathology, Ambroise Paré Hospital, AP-HP, Boulogne-Billancourt (J.-F.E.) - all in France; the Institute of Experimental Hematology, Hannover Medical School, Hannover, Germany (A.-L.N.); the Research Branch, Sidra Medicine (M.R., T.K., F.A.A., N. Marr), and the College of Health and Life Sciences, Hamad Bin Khalifa University (N. Marr), Doha, Qatar; and the Division of Pulmonary Medicine, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland (N. Mansouri).

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http://dx.doi.org/10.1056/NEJMoa1910640DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7063989PMC
January 2020

Pangenomic Classification of Pituitary Neuroendocrine Tumors.

Cancer Cell 2020 01 26;37(1):123-134.e5. Epub 2019 Dec 26.

INSERM U1016, Institut Cochin, 75014 Paris, France; CNRS UMR 8104, 75014 Paris, France; Université Paris Descartes-Université de Paris, 75006 Paris, France; Department of Endocrinology, Center for Rare Adrenal Diseases, Assistance Publique-Hôpitaux de Paris, Hôpital Cochin, 75014 Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2019.11.002DOI Listing
January 2020

Erdheim-Chester Disease: a Concise Review.

Curr Rheumatol Rep 2019 12 5;21(12):66. Epub 2019 Dec 5.

Sorbonne Université, Assistance Publique-Hôpitaux de Paris, Service de Médecine Interne 2, Centre National de Référence des Histiocytoses, Hôpital Pitié-Salpêtrière, 47-83, boulevard de l'Hôpital, 75651, Paris Cedex 13, France.

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http://dx.doi.org/10.1007/s11926-019-0865-2DOI Listing
December 2019

Lung Involvement in Destombes-Rosai-Dorfman Disease: Clinical and Radiological Features and Response to the MEK Inhibitor Cobimetinib.

Chest 2020 02 24;157(2):323-333. Epub 2019 Oct 24.

Service de Médecine Interne 2, Centre National de Référence Maladies Systémiques Rares et Histiocytoses, Sorbonne Université, Assistance Publique Hôpitaux de Paris, Hôpital de la Pitié-Salpêtrière, Paris, France. Electronic address:

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http://dx.doi.org/10.1016/j.chest.2019.09.036DOI Listing
February 2020

Plasma Biomarkers and Immune Checkpoint Inhibitors in Non-Small Cell Lung Cancer: New Tools for Better Patient Selection?

Cancers (Basel) 2019 Aug 29;11(9). Epub 2019 Aug 29.

Department of Respiratory Diseases and Thoracic Oncology, APHP-Hôpital Ambroise Paré, 92100 Boulogne-Billancourt, France.

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http://dx.doi.org/10.3390/cancers11091269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769436PMC
August 2019

Response to trametinib of histiocytosis with an activating mutation.

Leuk Lymphoma 2020 01 8;61(1):194-197. Epub 2019 Aug 8.

Pathology Department, Ambroise Paré Hospital, APHP, Boulogne, France.

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http://dx.doi.org/10.1080/10428194.2019.1650175DOI Listing
January 2020

Erdheim-Chester disease with concomitant Rosai-Dorfman like lesions: a distinct entity mainly driven by .

Haematologica 2020 01 23;105(1):e5-e8. Epub 2019 May 23.

Internal Medicine Department 2, Assistance Publique-Hôpitaux de Paris, French National Reference Center for Histiocytoses, Pitié-Salpêtrière Hospital, Paris, France

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http://dx.doi.org/10.3324/haematol.2019.216937DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6939531PMC
January 2020

Systemic Histiocytosis (Langerhans Cell Histiocytosis, Erdheim-Chester Disease, Destombes-Rosai-Dorfman Disease): from Oncogenic Mutations to Inflammatory Disorders.

Curr Oncol Rep 2019 05 21;21(7):62. Epub 2019 May 21.

Assistance Publique-Hôpitaux de Paris, Service de Médecine Interne 2, Centre National de Références des Histiocytoses, Hôpital Pitié-Salpêtrière, Sorbonne Université, 47-83, Boulevard de l'Hôpital, 75651, Paris Cedex 13, France.

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http://link.springer.com/10.1007/s11912-019-0810-6
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http://dx.doi.org/10.1007/s11912-019-0810-6DOI Listing
May 2019

Autoimmunity associated with Erdheim-Chester disease improves with BRAF/MEK inhibitors.

Haematologica 2019 11 28;104(11):e502-e505. Epub 2019 Mar 28.

Sorbonne Université, Assistance Publique Hôpitaux de Paris, Hôpital de la Pitié-Salpêtrière, Service de Médecine Interne 2, Centre National de Référence Maladies Systémiques Rares et Histiocytoses, Paris-75013.

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http://dx.doi.org/10.3324/haematol.2018.214007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6821627PMC
November 2019

Tubercular splenic abscesses: A rare entity sometimes hard to sterilize.

Int J Infect Dis 2019 05 5;82:18-20. Epub 2019 Mar 5.

Service de Maladies Infectieuses, Hôpital Raymond Poincaré, Garches, France. Electronic address:

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http://dx.doi.org/10.1016/j.ijid.2019.02.048DOI Listing
May 2019

CDKN2A Depletion Causes Aneuploidy and Enhances Cell Proliferation in Non-Immortalized Normal Human Cells.

Cancer Invest 2018 23;36(6):338-348. Epub 2018 Aug 23.

a EA4340, UVSQ , Boulogne-Billancourt , France.

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http://dx.doi.org/10.1080/07357907.2018.1491588DOI Listing
October 2018

Hypoalphalipoproteinemia and BRAF Mutation Are Major Predictors of Aortic Infiltration in the Erdheim-Chester Disease.

Arterioscler Thromb Vasc Biol 2018 08;38(8):1913-1925

Inserm, Institute of Cardiometabolism and Nutrition (ICAN), UMR_S1166, Hôpital de la Pitié, Sorbonne Université, Paris, France (M.G., F.S.-C., Y.A., E.F., P.L., W.L.G.).

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http://dx.doi.org/10.1161/ATVBAHA.118.310803DOI Listing
August 2018

Phenotypes and survival in Erdheim-Chester disease: Results from a 165-patient cohort.

Am J Hematol 2018 May 10;93(5):E114-E117. Epub 2018 Feb 10.

Internal Medicine Department 2, Pitié-Salpêtrière Hospital, French National Centre for Rare Systemic Diseases, AP-HP, Paris, 75013, France.

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http://doi.wiley.com/10.1002/ajh.25055
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http://dx.doi.org/10.1002/ajh.25055DOI Listing
May 2018

Efficacy of infliximab in the treatment of Erdheim-Chester disease.

Ann Rheum Dis 2018 09 23;77(9):1387-1390. Epub 2018 Jan 23.

Internal Medicine Department 2, AP-HP, French National Reference Centre for Rare Systemic Diseases, Pitié-Salpêtrière Hospital, Paris, France.

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http://dx.doi.org/10.1136/annrheumdis-2017-212678DOI Listing
September 2018

Molecular characterization of circulating tumor cells in lung cancer: moving beyond enumeration.

Oncotarget 2017 12 23;8(65):109818-109835. Epub 2017 Nov 23.

Department of Respiratory Diseases and Thoracic Oncology, APHP - Ambroise Pare Hospital, Boulogne-Billancourt, France.

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http://dx.doi.org/10.18632/oncotarget.22651DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5752564PMC
December 2017

Prevalence of Microsatellite Instability in Intraductal Papillary Mucinous Neoplasms of the Pancreas.

Gastroenterology 2018 03 20;154(4):1061-1065. Epub 2017 Nov 20.

INSERM, UMR S 938 - Centre de Recherche Saint-Antoine, Equipe Instabilité des Microsatellites et Cancers, Equipe labellisée par la Ligue Nationale contre le Cancer, F-75012, Paris, France; Sorbonne Université, Université Pierre et Marie Curie - Paris 6, Paris, France; AP-HP, Hôpitaux Universitaires Est Parisien, Hôpital Saint-Antoine, Service d'Anatomie et Cytologie Pathologiques, Paris, France. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2017.11.009DOI Listing
March 2018

Neurodegeneration in histiocytoses might start in utero.

Lancet Neurol 2017 12 27;16(12):953-954. Epub 2017 Oct 27.

Service de Médecine Interne 2, Centre de Référence des Histiocytoses, Institut E3M, AP-HP, Université Pierre et Marie Curie, Hôpital Pitié-Salpêtrière, Paris, France.

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http://dx.doi.org/10.1016/S1474-4422(17)30373-3DOI Listing
December 2017

High prevalence of myeloid neoplasms in adults with non-Langerhans cell histiocytosis.

Blood 2017 08 5;130(8):1007-1013. Epub 2017 Jul 5.

Service de Médecine Interne 2, Institut E3M, Centre de Références des Maladies Auto-Immunes et Systémiques Rares, Centre de Référence des Histiocytoses, Hôpital de la Pitié-Salpêtrière, Assistance Publique-Hôpitaux de Paris (AP-HP), Université Pierre et Marie Curie, Paris, France.

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http://dx.doi.org/10.1182/blood-2017-01-761718DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570678PMC
August 2017

Variation of mutant allele frequency in NRAS Q61 mutated melanomas.

BMC Dermatol 2017 07 1;17(1). Epub 2017 Jul 1.

Research Unit EA4340 Biomarkers in Cancerology and Hemato Oncology, Versailles SQY University, Paris-Saclay University, 9, Avenue Charles de Gaulle, 92104, Boulogne-Billancourt, France.

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http://dx.doi.org/10.1186/s12895-017-0061-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5494128PMC
July 2017

Targeted therapies in 54 patients with Erdheim-Chester disease, including follow-up after interruption (the LOVE study).

Blood 2017 09 30;130(11):1377-1380. Epub 2017 Jun 30.

Department of Internal Medicine 2, Assistance Publique-Hôpitaux de Paris (AP-HP), Pitié-Salpêtrière Hospital, French National Centre for Rare Systemic Diseases, Paris, France.

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http://www.bloodjournal.org/lookup/doi/10.1182/blood-2017-03
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http://dx.doi.org/10.1182/blood-2017-03-771873DOI Listing
September 2017

Histiocytoses: emerging neoplasia behind inflammation.

Lancet Oncol 2017 02;18(2):e113-e125

Service de Médecine Interne 2, Centre National de Référence Maladies Auto Immunes Systémiques Rares, Institut E3M, Hôpital Pitié-Salpêtrière, Paris, France.

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http://dx.doi.org/10.1016/S1470-2045(17)30031-1DOI Listing
February 2017

Mutational signature analysis identifies MUTYH deficiency in colorectal cancers and adrenocortical carcinomas.

J Pathol 2017 05 29;242(1):10-15. Epub 2017 Mar 29.

INSERM UMR-S1147, Personalized Medicine, Pharmacogenomics, Therapeutic Optimization, Université Paris Descartes, Paris, France.

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http://dx.doi.org/10.1002/path.4880DOI Listing
May 2017

Prognostic Value of BRAF and KRAS Mutations in MSI and MSS Stage III Colon Cancer.

J Natl Cancer Inst 2017 05 31;109(5). Epub 2016 Dec 31.

Affiliations of authors: Department of Gastroenterology and GI Oncology, Université Paris Descartes, Hopital Européen Georges Pompidou, Paris, France (JTai); Fédération Francophone de Cancérologie Digestive (FFCD), Dijon, France (KLM); Alliance Statistics and Data Center, Mayo Clinic, Rochester, MN (QS, DJS); Department of Pathology, Centre Jean Perrin, EA ERTICa, Université d'Auvergne, Clermont-Ferrand, France (FPL); Centre Hospitalier Universitaire Robert Debré, Reims, France (OB); Medical Oncology Department, Vall d'Hebron University Hospital and Institute of Oncology (VHIO), Barcelona, Spain (JTab); Spanish Gastrointestinal Tumors TTD Group, Universitat Autònoma de Barcelona, Barcelona, Spain (JTab); Section of Clinical Pharmacology and Oncology, Department of Health Sciences, University of Florence, Florence, Italy (EM); Division of Medical Oncology, Ohio State University Comprehensive Cancer Center, Columbus, OH (RMG); First Medical Department, University Hospital Carl Gustav Carus, Dresden, Germany (GF); Department of Gastroenterology, Hôpital Universitaire Erasme, Brussels, Belgium (JLVL); Department of Oncology, Mayo Clinic and Mayo Cancer Center, Rochester, MN (SRA, FAS); Pathology Department, Ambroise Paré Hospital, Boulogne, France (JFE); Université Paris Descartes, Sorbonne Paris Cité, France (PLP); Assistance Publique Hôpitaux de Paris, Department of Biology, Hôpital Européen Georges Pompidou, Paris, France (PLP); INSERM UMR-S1147, Paris, France (PLP).

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http://dx.doi.org/10.1093/jnci/djw272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075212PMC
May 2017

Efficacy of the MEK inhibitor cobimetinib for wild-type BRAF Erdheim-Chester disease.

Br J Haematol 2018 01 6;180(1):150-153. Epub 2016 Oct 6.

Internal Medicine Department, French National Center for Rare Systemic Diseases, Pitié-Salpêtrière Hospital, AP-HP, Paris, France.

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http://doi.wiley.com/10.1111/bjh.14284
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http://dx.doi.org/10.1111/bjh.14284DOI Listing
January 2018

BRAF Mutation Correlates With High-Risk Langerhans Cell Histiocytosis and Increased Resistance to First-Line Therapy.

J Clin Oncol 2016 09 5;34(25):3023-30. Epub 2016 Jul 5.

Sébastien Héritier, Mohamed-Aziz Barkaoui, Jean Miron, and Jean Donadieu, French Reference Center for Langerhans Cell Histiocytosis, Trousseau Hospital; Sébastien Héritier, Sabah Boudjemaa, Guy Leverger, and Jean Donadieu, Trousseau Hospital, Assistance Publique-Hôpitaux de Paris; Sylvie Fraitag, Despina Moshous, and Christine Bodemer, Necker Hospital, Assistance Publique-Hôpitaux de Paris; Michel Peuchmaur and Brigitte Lescoeur, Robert Debré Hospital, Assistance Publique-Hôpitaux de Paris; Michel Peuchmaur, Université Paris Diderot, Sorbonne Paris Cité; Hélène Pacquement, Institut Curie Medical Center; Guy Leverger, Université Pierre et Marie Curie; Fleur Cohen-Aubart and Julien Haroche, Pitié-Salpêtrière Hospital, Assistance Publique-Hôpitaux de Paris; Roger Lacave, Tenon Hospital, Assistance Publique-Hôpitaux de Paris; Valérie Taly, Institut National de la Santé et de la Recherche Médicale, Unités Mixte de Recherche S1147, Centre National de la Recherche Scientifique SNC 5014, Université Paris Sorbonne Cité, Paris; Sébastien Héritier, Jean-François Emile, Zofia Hélias-Rodzewicz, and Jean Donadieu, Université de Versailles Saint-Quentin-en-Yvelines, Université Paris-Saclay; Jean-François Emile, Ambroise Paré Hospital, Assistance Publique-Hôpitaux de Paris, Boulogne-Billancourt; Caroline Thomas and Anne Moreau, Centre Hospitalo-Universitaire de Nantes, Nantes; Florence Renaud, Centre Hospitalier Régional Universitaire, Université de Lille; Anne Lambilliotte and Françoise Mazingue, Centre Hospitalo-Universitaire de Lille, Lille; Catherine Chassagne-Clément, Centre Léon Bérard; Frédérique Dijoud, Hôpital Femme-Mère-Enfant, Hospices Civils de Lyon; Kamila Kebaili, Institut d'Hémato-Oncologie Pediatrique, Lyon; Valérie Rigau, Gui de Chauliac Hospital; Eric Jeziorski, Hôpital Arnaud de Villeneuve, Montpellier; Geneviève Plat, Centre Hospitalo-Universitaire de Toulouse, Toulouse; Nathalie Aladjidi, Centre Hospitalo-Universit

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http://ascopubs.org/doi/10.1200/JCO.2015.65.9508
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http://dx.doi.org/10.1200/JCO.2015.65.9508DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5321082PMC
September 2016

[Erdheim-Chester disease (ECD), an inflammatory myeloid neoplasia].

Presse Med 2017 Jan 24;46(1):96-106. Epub 2016 May 24.

Assistance publique-Hôpitaux de Paris, hôpital Pitié-Salpêtrière, université Pierre-et-Marie-Curie Paris 6, institut E3M, centre de référence des maladies rares auto-immunes et systémiques, service de médecine interne 2, Paris, France.

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http://dx.doi.org/10.1016/j.lpm.2016.02.025DOI Listing
January 2017

Superior efficacy and tolerance of reduced doses of vemurafenib plus anakinra in Erdheim-Chester disease: Towards the paradigm of combined targeting and immune therapies.

Acta Oncol 2016 Jul 31;55(7):930-2. Epub 2016 Mar 31.

a Department of Internal Medicine and Clinical Immunology , CHU Côte De Nacre, Université Basse Normandie , Caen , France.

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http://dx.doi.org/10.3109/0284186X.2015.1120885DOI Listing
July 2016

Increase in NRAS mutant allele percentage during metastatic melanoma progression.

Exp Dermatol 2016 06 18;25(6):472-4. Epub 2016 May 18.

Research Unit EA 4340 'Biomarkers in cancerology and in hemato-oncology', Université de Versailles-Saint-Quentin-en-Yvelines, Université Paris-Saclay, Boulogne-Billancourt, France.

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http://dx.doi.org/10.1111/exd.13001DOI Listing
June 2016

[Histiocytoses: General classification and molecular criteria].

Presse Med 2017 Jan 4;46(1):46-54. Epub 2016 Mar 4.

Hôpital Ambroise-Paré, service de pathologie, 44000 Nantes, France.

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http://dx.doi.org/10.1016/j.lpm.2016.01.016DOI Listing
January 2017

Cutaneous manifestations of Erdheim-Chester disease (ECD): Clinical, pathological, and molecular features in a monocentric series of 40 patients.

J Am Acad Dermatol 2016 Mar 16;74(3):513-20. Epub 2016 Jan 16.

E3M Institute, Service de Medecine Interne 2, French National Reference Center for Rare Systemic and Autoimmune Diseases, Assistance Publique Hôpitaux de Paris (AP-HP), Groupement Hospitalier Pitié-Salpêtrière, Paris, France; Sorbonne Universités, Université Pierre et Marie Curie (UPMC) Université Paris VI, Paris, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S01909622150247
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http://dx.doi.org/10.1016/j.jaad.2015.11.007DOI Listing
March 2016

Prognostic Effect of BRAF and KRAS Mutations in Patients With Stage III Colon Cancer Treated With Leucovorin, Fluorouracil, and Oxaliplatin With or Without Cetuximab: A Post Hoc Analysis of the PETACC-8 Trial.

JAMA Oncol 2016 May;2(5):643-653

Centre de Recherché UMR-S 1147, Médecine Personnalisée, Pharmacogénomique, Optimisation Thérapeutique, Institut National de la Santé et de la Recherche Médicale, Paris, France6Paris Descartes University, Department of Biology, European Georges Pompidou Ho.

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http://dx.doi.org/10.1001/jamaoncol.2015.5225DOI Listing
May 2016

Asparagine Synthetase Expression and Phase I Study With L-Asparaginase Encapsulated in Red Blood Cells in Patients With Pancreatic Adenocarcinoma.

Pancreas 2015 Oct;44(7):1141-7

From the *Department of Hepato-Gastroenterology, Pitié Salpêtrière Hospital, Paris; and †Erytech Pharma, Lyon, France; ‡Department of Gastroenterology, Erasme University Hospital, Brussels, Belgium; §Department of Oncology, Centre François Baclesse, Caen; ∥Department of Oncology, Centre Oscar Lambret, Lille; and ¶Pathology Department, Beaujon Hospital, Paris, France; #Department of Pathology, Erasme Hospital, Brussels, Belgium; **Department of Pathology, Saint Antoine Hospital; and ††Department of Pathology, Pitié Salpêtrière Hospital, Paris; ‡‡Department of Pathology, Ambroise Paré Hospital, Boulogne-Billancourt; and §§Department of Gastroenterology, Beaujon Hospital; and Departments of ∥∥Medical Oncology and ¶¶Oncology, Saint-Antoine Hospital, Paris, France.

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http://dx.doi.org/10.1097/MPA.0000000000000394DOI Listing
October 2015

The histiocytosis Erdheim-Chester disease is an inflammatory myeloid neoplasm.

Expert Rev Clin Immunol 2015 21;11(9):1033-42. Epub 2015 Jul 21.

Department of Internal Medicine and French Reference Center for Rare Autoimmune and Systemic Diseases, Assistance Publique-Hôpitaux de Paris, Pitié-Salpêtrière Hospital, Paris, France.

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http://dx.doi.org/10.1586/1744666X.2015.1060857DOI Listing
May 2016

Vemurafenib Use in an Infant for High-Risk Langerhans Cell Histiocytosis.

JAMA Oncol 2015 Sep;1(6):836-8

Department of Pediatric Hematology and Oncology, Trousseau Hospital, Assistance Publique-Hôpitaux de Paris (APHP), Paris, France Trousseau Hospital, Paris, France.

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http://dx.doi.org/10.1001/jamaoncol.2015.0736DOI Listing
September 2015

Vemurafenib as first line therapy in BRAF-mutated Langerhans cell histiocytosis.

J Am Acad Dermatol 2015 Jul;73(1):e29-30

Department of Internal Medicine and French Reference Center for Rare Auto-immune and Systemic Diseases, Assistance Publique-Hôpitaux de Paris (AP-HP), Pitié-Salpêtrière Hospital, Paris, France; Université Pierre et Marie Curie, UPMC University Paris 6, Paris, France.

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http://dx.doi.org/10.1016/j.jaad.2014.10.045DOI Listing
July 2015

Common cancer-associated PIK3CA activating mutations rarely occur in Langerhans cell histiocytosis.

Blood 2015 Apr;125(15):2448-9

EA4340, Versailles University, Boulogne-Billancourt, France Pathology Department, Ambroise Paré Hospital, Assistance Publique Hôpitaux de Paris, Boulogne-Billancourt, France.

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http://dx.doi.org/10.1182/blood-2015-01-625491DOI Listing
April 2015

Complete remission of critical neurohistiocytosis by vemurafenib.

Neurol Neuroimmunol Neuroinflamm 2015 Apr 26;2(2):e78. Epub 2015 Feb 26.

Departments of Neurology (P.E., A.M.), Nuclear Medicine (R.B.), and Dermatology (S.V.), Charité Universitätsmedizin Berlin, Germany; Service de Médecine Interne (J.H.), Hôpital Pitié-Salpêtrière, Paris, France; and Service de Pathologie (J.-F.E.), Hôpital universitaire Ambroise Paré, Paris, France.

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http://dx.doi.org/10.1212/NXI.0000000000000078DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4345630PMC
April 2015