Jean-Claude Martinou

Jean-Claude Martinou

UNVERIFIED PROFILE

Are you Jean-Claude Martinou?   Register this Author

Register author
Jean-Claude Martinou

Jean-Claude Martinou

Publications by authors named "Jean-Claude Martinou"

Are you Jean-Claude Martinou?   Register this Author

98Publications

2219Reads

36Profile Views

Development and validation of a chiral UHPLC-MS method for the analysis of cysteine enantiomers in biological samples.

J Pharm Biomed Anal 2020 Jan 27;177:112841. Epub 2019 Aug 27.

School of Pharmaceutical Sciences, University of Geneva, University of Lausanne, Geneva, Switzerland; Swiss Centre for Applied Human Toxicology (SCAHT), Switzerland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jpba.2019.112841DOI Listing
January 2020

The mitochondrial carrier pathway transports non-canonical substrates with an odd number of transmembrane segments.

BMC Biol 2020 Jan 6;18(1). Epub 2020 Jan 6.

Institute of Biochemistry and Molecular Biology, ZBMZ, Faculty of Medicine, University of Freiburg, 79104, Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/s12915-019-0733-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945462PMC
January 2020

Feasibility of neurochemically profiling mouse embryonic brain and its development in utero using H MRS at 14.1 T.

NMR Biomed 2019 Nov 19;32(11):e4163. Epub 2019 Aug 19.

Faculty of Science, University of Geneva, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/nbm.4163DOI Listing
November 2019

stabilization of OPA1 in hepatocytes potentiates mitochondrial respiration and gluconeogenesis in a prohibitin-dependent way.

J Biol Chem 2019 Aug 8;294(34):12581-12598. Epub 2019 Jul 8.

Department of Cell Physiology and Metabolism, University of Geneva Medical Centre, 1206 Geneva, Switzerland

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.RA119.007601DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6709633PMC
August 2019

The yeast mitochondrial pyruvate carrier is a hetero-dimer in its functional state.

EMBO J 2019 05 12;38(10). Epub 2019 Apr 12.

Medical Research Council Mitochondrial Biology Unit, University of Cambridge, Cambridge, UK

View Article

Download full-text PDF

Source
http://dx.doi.org/10.15252/embj.2018100785DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6517818PMC
May 2019

Lethal Poisoning of Cancer Cells by Respiratory Chain Inhibition plus Dimethyl α-Ketoglutarate.

Cell Rep 2019 04;27(3):820-834.e9

Centre de Recherche des Cordeliers, INSERM, Sorbonne Université, USPC, Université Paris Descartes, Université Paris Diderot, Equipe 11 labellisée par la Ligue contre le Cancer, 75006 Paris, France; Metabolomics and Cell Biology Platforms, Institut Gustave Roussy, 94805 Villejuif, France. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.celrep.2019.03.058DOI Listing
April 2019

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Authors:
Lorenzo Galluzzi Ilio Vitale Stuart A Aaronson John M Abrams Dieter Adam Patrizia Agostinis Emad S Alnemri Lucia Altucci Ivano Amelio David W Andrews Margherita Annicchiarico-Petruzzelli Alexey V Antonov Eli Arama Eric H Baehrecke Nickolai A Barlev Nicolas G Bazan Francesca Bernassola Mathieu J M Bertrand Katiuscia Bianchi Mikhail V Blagosklonny Klas Blomgren Christoph Borner Patricia Boya Catherine Brenner Michelangelo Campanella Eleonora Candi Didac Carmona-Gutierrez Francesco Cecconi Francis K-M Chan Navdeep S Chandel Emily H Cheng Jerry E Chipuk John A Cidlowski Aaron Ciechanover Gerald M Cohen Marcus Conrad Juan R Cubillos-Ruiz Peter E Czabotar Vincenzo D'Angiolella Ted M Dawson Valina L Dawson Vincenzo De Laurenzi Ruggero De Maria Klaus-Michael Debatin Ralph J DeBerardinis Mohanish Deshmukh Nicola Di Daniele Francesco Di Virgilio Vishva M Dixit Scott J Dixon Colin S Duckett Brian D Dynlacht Wafik S El-Deiry John W Elrod Gian Maria Fimia Simone Fulda Ana J García-Sáez Abhishek D Garg Carmen Garrido Evripidis Gavathiotis Pierre Golstein Eyal Gottlieb Douglas R Green Lloyd A Greene Hinrich Gronemeyer Atan Gross Gyorgy Hajnoczky J Marie Hardwick Isaac S Harris Michael O Hengartner Claudio Hetz Hidenori Ichijo Marja Jäättelä Bertrand Joseph Philipp J Jost Philippe P Juin William J Kaiser Michael Karin Thomas Kaufmann Oliver Kepp Adi Kimchi Richard N Kitsis Daniel J Klionsky Richard A Knight Sharad Kumar Sam W Lee John J Lemasters Beth Levine Andreas Linkermann Stuart A Lipton Richard A Lockshin Carlos López-Otín Scott W Lowe Tom Luedde Enrico Lugli Marion MacFarlane Frank Madeo Michal Malewicz Walter Malorni Gwenola Manic Jean-Christophe Marine Seamus J Martin Jean-Claude Martinou Jan Paul Medema Patrick Mehlen Pascal Meier Sonia Melino Edward A Miao Jeffery D Molkentin Ute M Moll Cristina Muñoz-Pinedo Shigekazu Nagata Gabriel Nuñez Andrew Oberst Moshe Oren Michael Overholtzer Michele Pagano Theocharis Panaretakis Manolis Pasparakis Josef M Penninger David M Pereira Shazib Pervaiz Marcus E Peter Mauro Piacentini Paolo Pinton Jochen H M Prehn Hamsa Puthalakath Gabriel A Rabinovich Markus Rehm Rosario Rizzuto Cecilia M P Rodrigues David C Rubinsztein Thomas Rudel Kevin M Ryan Emre Sayan Luca Scorrano Feng Shao Yufang Shi John Silke Hans-Uwe Simon Antonella Sistigu Brent R Stockwell Andreas Strasser Gyorgy Szabadkai Stephen W G Tait Daolin Tang Nektarios Tavernarakis Andrew Thorburn Yoshihide Tsujimoto Boris Turk Tom Vanden Berghe Peter Vandenabeele Matthew G Vander Heiden Andreas Villunger Herbert W Virgin Karen H Vousden Domagoj Vucic Erwin F Wagner Henning Walczak David Wallach Ying Wang James A Wells Will Wood Junying Yuan Zahra Zakeri Boris Zhivotovsky Laurence Zitvogel Gerry Melino Guido Kroemer

Cell Death Differ 2018 03 23;25(3):486-541. Epub 2018 Jan 23.

Paris Descartes/Paris V University, Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41418-017-0012-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864239PMC
March 2018

The FASTK family of proteins: emerging regulators of mitochondrial RNA biology.

Nucleic Acids Res 2017 Nov;45(19):10941-10947

Departamento de Enfermería, Universidad de Valladolid, Instituto de Biología y Genética Molecular, Valladolid 47003, Spain.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/nar/gkx772DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5737537PMC
November 2017

The mitochondrial pyruvate carrier in health and disease: To carry or not to carry?

Biochim Biophys Acta 2016 10 26;1863(10):2436-42. Epub 2016 Jan 26.

Department of Cell Biology, University of Geneva, 30 quai Ernest-Ansermet, 1211 Genève 4, Switzerland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbamcr.2016.01.017DOI Listing
October 2016

Channels and transporters in cell metabolism.

Biochim Biophys Acta 2016 10 3;1863(10):2359-61. Epub 2016 Jun 3.

Department of Cell Biology, University of Geneva, 30 quai Ernest Ansermet, 1211 Geneva 4, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbamcr.2016.06.001DOI Listing
October 2016

Solange Desagher and Jean-Claude Martinou: Executioners of Cell Death.

Trends Cell Biol 2016 08 20;26(8):560-562. Epub 2016 Jun 20.

Université de Montpellier, 163 rue Auguste Broussonnet, 34090 Montpellier, France; University of Geneva, Department of Cell Biology, 30 Quai Ernest-Ansermet, 1211 Geneva 4, Switzerland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.tcb.2016.05.010DOI Listing
August 2016

Mitochondrial RNA granules: Compartmentalizing mitochondrial gene expression.

J Cell Biol 2016 Mar 7;212(6):611-4. Epub 2016 Mar 7.

Department of Cell Biology, University of Geneva, 1211 Genève, Switzerland

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1083/jcb.201507125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792075PMC
March 2016

TCTP contains a BH3-like domain, which instead of inhibiting, activates Bcl-xL.

Sci Rep 2016 Jan 27;6:19725. Epub 2016 Jan 27.

Département de Biologie Structurale Intégrative, Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Université de Strasbourg, CNRS UMR 7104, INSERM U964, 1 rue Laurent Fries, BP 10142, F-67404 Illkirch, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/srep19725DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4728560PMC
January 2016

Non-microtubular localizations of microtubule-associated protein 6 (MAP6).

PLoS One 2014 19;9(12):e114905. Epub 2014 Dec 19.

Inserm, U836, Physiopathologie du cytosquelette, BP170, Grenoble, France; University Grenoble Alpes, Grenoble Institut des Neurosciences, BP170, Grenoble, France; Commissariat à l'énergie atomique, Institut de Recherches en Technologies et Sciences pour le Vivant, Groupe Physiopathologie du Cytosquelette, Grenoble, France.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0114905PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4272302PMC
December 2015

Mitochondrial pyruvate import and its effects on homeostasis.

Curr Opin Cell Biol 2015 Apr 15;33:35-41. Epub 2014 Nov 15.

Department of Cell Biology, University of Geneva, Quai Ernest-Ansermet 30, 1211 Geneva 4, Switzerland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ceb.2014.10.008DOI Listing
April 2015

C11orf83, a mitochondrial cardiolipin-binding protein involved in bc1 complex assembly and supercomplex stabilization.

Mol Cell Biol 2015 Apr 20;35(7):1139-56. Epub 2015 Jan 20.

Department of Human Protein Sciences, University of Geneva, Geneva, Switzerland CALIPHO Group, SIB Swiss Institute of Bioinformatics, Geneva, Switzerland

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/MCB.01047-14DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4355537PMC
April 2015

Regulation of mitochondrial pyruvate uptake by alternative pyruvate carrier complexes.

EMBO J 2015 Apr 11;34(7):911-24. Epub 2015 Feb 11.

Department of Cell Biology, University of Geneva, Genève, Switzerland

View Article

Download full-text PDF

Source
http://dx.doi.org/10.15252/embj.201490197DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388599PMC
April 2015

A mitochondria-specific isoform of FASTK is present in mitochondrial RNA granules and regulates gene expression and function.

Cell Rep 2015 Feb 19;10(7):1110-21. Epub 2015 Feb 19.

Department of Cell Biology, University of Geneva, 30 quai Ernest-Ansermet, 1211 Genève 4, Switzerland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.celrep.2015.01.063DOI Listing
February 2015

MLKL compromises plasma membrane integrity by binding to phosphatidylinositol phosphates.

Cell Rep 2014 May 9;7(4):971-81. Epub 2014 May 9.

VIB Inflammation Research Center, Technologiepark 927, 9052 Zwijnaarde-Ghent, Belgium; Department of Biomedical Molecular Biology, Ghent University, Technologiepark 927, 9052 Zwijnaarde-Ghent, Belgium; Methusalem Program, Ghent University, Technologiepark 927, 9052 Zwijnaarde-Ghent, Belgium. Electronic address:

View Article

Download full-text PDF

Source
http://www.cell.com/cell-reports/pdf/S2211-1247(14)00328-3.p
Web Search
http://linkinghub.elsevier.com/retrieve/pii/S221112471400328
Publisher Site
http://dx.doi.org/10.1016/j.celrep.2014.04.026DOI Listing
May 2014

Involvement of cardiolipin in tBID-induced activation of BAX during apoptosis.

Chem Phys Lipids 2014 Apr 12;179:70-4. Epub 2013 Dec 12.

Department of Cell Biology, University of Geneva, 30 Quai Ernest Ansermet, 1211 Geneva 4, Switzerland. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.chemphyslip.2013.12.002DOI Listing
April 2014

TAT-RasGAP317-326-mediated tumor cell death sensitization can occur independently of Bax and Bak.

Apoptosis 2014 Apr;19(4):719-33

Department of Physiology, University of Lausanne, Rue du Bugnon 7, 1005, Lausanne, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10495-013-0958-8DOI Listing
April 2014

Life without the mitochondrial calcium uniporter.

Nat Cell Biol 2013 Dec;15(12):1398-400

Department of Cell Biology, University of Geneva, 1211 Geneva 4, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncb2891DOI Listing
December 2013

TRAIL promotes membrane blebbing, detachment and migration of cells displaying a dysfunctional intrinsic pathway of apoptosis.

Apoptosis 2013 Mar;18(3):324-36

Department of Cell Biology, University of Geneva, Sciences III, 30 quai Ernest Ansermet, 1211 Geneva 4, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10495-012-0782-6DOI Listing
March 2013

GRSF1 regulates RNA processing in mitochondrial RNA granules.

Cell Metab 2013 Mar;17(3):399-410

Department of Cell Biology, University of Geneva, 30 Quai Ernest-Ansermet, 1211 Genève 4, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cmet.2013.02.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3593211PMC
March 2013

Where killers meet--permeabilization of the outer mitochondrial membrane during apoptosis.

Cold Spring Harb Perspect Biol 2013 Jan 1;5(1):a011106. Epub 2013 Jan 1.

Department of Cell Biology, University of Geneva, 1211 Geneva 4, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/cshperspect.a011106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3579396PMC
January 2013

Intermembrane space proteome of yeast mitochondria.

Mol Cell Proteomics 2012 Dec 15;11(12):1840-52. Epub 2012 Sep 15.

Institut für Biochemie und Molekularbiologie, ZBMZ, Universität Freiburg, 79104 Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/mcp.M112.021105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3518125PMC
December 2012

Identification and functional expression of the mitochondrial pyruvate carrier.

Science 2012 Jul 24;337(6090):93-6. Epub 2012 May 24.

Department of Cell Biology, University of Geneva, Geneva, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/science.1218530DOI Listing
July 2012

Sensitization of (colon) cancer cells to death receptor related therapies: a report from the FP6-ONCODEATH research consortium.

Cancer Biol Ther 2012 May 1;13(7):458-66. Epub 2012 May 1.

Institute of Biological Research and Biotechnology, National Hellenic Research Foundation, Athens, Greece.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4161/cbt.19600DOI Listing
May 2012

Mitochondria in apoptosis: Bcl-2 family members and mitochondrial dynamics.

Dev Cell 2011 Jul;21(1):92-101

Department of Cell Biology, University of Geneva, Faculty of Sciences, 30 quai Ernest-Ansermet, Geneva 4, Switzerland.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S15345807110025
Publisher Site
http://dx.doi.org/10.1016/j.devcel.2011.06.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3156409PMC
July 2011

Bioenergetic defect associated with mKATP channel opening in a mouse model carrying a mitofusin 2 mutation.

FASEB J 2011 May 1;25(5):1618-27. Epub 2011 Feb 1.

Unité Mixte de Recherche Centre National de Recherche Scientifique (CNRS) 6214, Institut National de Santé et de Recherche Me´dicale (INSERM) U771, Angers, France.

View Article

Download full-text PDF

Source
http://www.fasebj.org/content/25/5/1618.full.pdf
Web Search
http://www.fasebj.org/cgi/doi/10.1096/fj.10-173609
Publisher Site
http://dx.doi.org/10.1096/fj.10-173609DOI Listing
May 2011

Mitochondrial outer membrane permeabilization during apoptosis: the role of mitochondrial fission.

Biochim Biophys Acta 2011 Apr 28;1813(4):540-5. Epub 2011 Jan 28.

Department of Cell Biology, University of Geneva, Sciences III, 30 quai Ernest Ansermet, 1211 Geneva 4, Switzerland.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S01674889110002
Publisher Site
http://dx.doi.org/10.1016/j.bbamcr.2011.01.021DOI Listing
April 2011

[Mitochondrial dynamics: from geometry to function].

Med Sci (Paris) 2010 Oct;26(10):783-5

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1051/medsci/20102610783DOI Listing
October 2010

Mitochondrial dynamics: quantifying mitochondrial fusion in vitro.

BMC Biol 2010 Jul 26;8:99. Epub 2010 Jul 26.

Department of Cell Biology, University of Geneva, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1741-7007-8-99DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2909948PMC
July 2010

Expression of mitofusin 2(R94Q) in a transgenic mouse leads to Charcot-Marie-Tooth neuropathy type 2A.

Brain 2010 May;133(Pt 5):1460-9

Department of Cell Biology, University of Geneva, 30 quai Ernest-Ansermet, 1211 Genève 4, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/brain/awq082DOI Listing
May 2010

SLP-2 negatively modulates mitochondrial sodium-calcium exchange.

Cell Calcium 2010 Jan 26;47(1):11-8. Epub 2009 Nov 26.

Department of Cell Biology, University of Geneva, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ceca.2009.10.005DOI Listing
January 2010

Mitochondrial outer-membrane permeabilization and remodelling in apoptosis.

Int J Biochem Cell Biol 2009 Oct 9;41(10):1884-9. Epub 2009 May 9.

Department of Cell Biology, University of Geneva, Quai Ernest-Ansermet 30, 1211 Geneva 4, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.biocel.2009.05.001DOI Listing
October 2009

Autophagy: evolutionary and pathophysiological insights.

Biochim Biophys Acta 2009 Sep;1793(9):1395-6

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbamcr.2009.08.001DOI Listing
September 2009

Role of mitofusin 2 mutations in the physiopathology of Charcot-Marie-Tooth disease type 2A.

Exp Neurol 2009 Aug 8;218(2):268-73. Epub 2009 May 8.

Department of Cell Biology, Genève, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.expneurol.2009.05.003DOI Listing
August 2009

Apoptotic cells provide an unexpected source of Wnt3 signaling to drive hydra head regeneration.

Dev Cell 2009 Aug;17(2):279-89

Department of Zoology and Animal Biology, University of Geneva, 30 Quai Ernest Ansermet, CH-1211 Geneva 4, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.devcel.2009.07.014DOI Listing
August 2009

Mitochondrial dynamics and cancer.

Semin Cancer Biol 2009 Feb 24;19(1):50-6. Epub 2008 Dec 24.

Department of Cell Biology, University of Geneva, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.semcancer.2008.12.001DOI Listing
February 2009

Selective actions of mitochondrial fission/fusion genes on metabolism-secretion coupling in insulin-releasing cells.

J Biol Chem 2008 Nov 2;283(48):33347-56. Epub 2008 Oct 2.

Department of Cell Physiology and Metabolism, University of Geneva, CH-1211, Geneva 4, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M806251200DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2662262PMC
November 2008

Mitochondrial dynamics and apoptosis: a painful separation.

Dev Cell 2008 Sep;15(3):341-3

Clinical and Experimental Pharmacology, Paterson Institute for Cancer Research, University of Manchester, Wilmslow Road, Manchester M20 4BX, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.devcel.2008.08.011DOI Listing
September 2008

Purification and proteomic analysis of the mouse liver mitochondrial inner membrane.

Methods Mol Biol 2008 ;432:101-16

Department of Cell Biology, University of Geneva, Geneva, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-59745-028-7_7DOI Listing
August 2008

SLP-2 interacts with prohibitins in the mitochondrial inner membrane and contributes to their stability.

Biochim Biophys Acta 2008 May 20;1783(5):904-11. Epub 2008 Feb 20.

Department of Cell Biology, University of Geneva, Geneva, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbamcr.2008.02.006DOI Listing
May 2008

Granzyme a, a stealth killer in the mitochondrion.

Cell 2008 May;133(4):568-70

Department of Cell Biology, University of Geneva, 30 quai Ernest-Ansermet, Geneva CH-1211, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cell.2008.04.031DOI Listing
May 2008

Mitochondrial dynamics: to be in good shape to survive.

Curr Mol Med 2008 Mar;8(2):131-7

Department of Cell Biology, University of Geneva, Quai Ernest-Ansermet 30, 1211 Geneva 4, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.2174/156652408783769625DOI Listing
March 2008

Mechanisms of mitochondrial outer membrane permeabilization.

Novartis Found Symp 2007 ;287:170-6; discussion 176-82

Department of Cell Biology, University of Geneva, Quai Ernest-Ansermet 30, Geneva, Switzerland.

View Article

Download full-text PDF

Source
January 2008

Preprotein transport machineries of yeast mitochondrial outer membrane are not required for Bax-induced release of intermembrane space proteins.

J Mol Biol 2007 Apr 12;368(1):44-54. Epub 2007 Jan 12.

Institut für Biochemie und Molekularbiologie, Zentrum für Biochemie und Molekulare Zellforschung, Universität Freiburg, Hermann-Herder-Strasse 7, D-79104 Freiburg, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jmb.2007.01.016DOI Listing
April 2007

The mitochondrial fission protein hFis1 requires the endoplasmic reticulum gateway to induce apoptosis.

Mol Biol Cell 2006 Nov 16;17(11):4593-605. Epub 2006 Aug 16.

Dulbecco-Telethon Institute, Venetian Institute of Molecular Medicine, I-35129 Padova, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1091/mbc.e06-05-0377DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1635393PMC
November 2006

Inhibiting the mitochondrial fission machinery does not prevent Bax/Bak-dependent apoptosis.

Mol Cell Biol 2006 Oct;26(20):7397-408

Department of Cell Biology, University of Geneva, Quai Ernest-Ansermet 30, 1211 Geneva 4, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1128/MCB.02282-05DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1636857PMC
October 2006

Mitochondrial fission and apoptosis: an ongoing trial.

Biochim Biophys Acta 2006 May-Jun;1763(5-6):522-30. Epub 2006 Apr 20.

Department of Cell Biology, University of Geneva, Quai Ernest-Ansermet 30, 1211 Geneva 4, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbamcr.2006.04.005DOI Listing
September 2006

[Changes in the outer mitochondrial membranes during apoptosis].

J Soc Biol 2005 ;199(3):207-10

Département de biologie cellulaire, Université de Genève, 30, quai Ernest-Ansermet, 1211 Genève 4, Suisse.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1051/jbio:2005021DOI Listing
March 2006

Bax channel inhibitors prevent mitochondrion-mediated apoptosis and protect neurons in a model of global brain ischemia.

J Biol Chem 2005 Dec 11;280(52):42960-70. Epub 2005 Oct 11.

Serono Pharmaceutical Research Institute, 14 chemin des Aulx, CH-1228 Plan-les-Ouates, Geneva, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M505843200DOI Listing
December 2005

Building the mitochondrial proteome.

Expert Rev Proteomics 2005 Aug;2(4):541-51

Department of Cellular Biology, University of Geneva, 30 quai E. Ansermet, 1205 Geneva, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1586/14789450.2.4.541DOI Listing
August 2005

The properties of the mitochondrial megachannel in mitoplasts from human colon carcinoma cells are not influenced by Bax.

FEBS Lett 2005 Jul;579(17):3695-700

CNR Institute of Neuroscience, Biomembranes Section, Department of Biomedical Sciences, University of Padova, Viale Giuseppe Colombo 3, 35121 Padova, Italy.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1016/j.febslet.2005.05.055
Publisher Site
http://dx.doi.org/10.1016/j.febslet.2005.05.055DOI Listing
July 2005

Regulation of Bcl-2 proteins and of the permeability of the outer mitochondrial membrane.

C R Biol 2005 Jul;328(7):616-31

Department of Cell Biology, University of Geneva, 30, quai Ernest-Ansermet, 1211 Genève 4, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.crvi.2005.05.002DOI Listing
July 2005

Pro-apoptotic Bid induces membrane perturbation by inserting selected lysolipids into the bilayer.

Biochem J 2005 Apr;387(Pt 1):109-18

School of Biological Sciences, The University of Manchester, Stopford Building, Oxford Road, Manchester M13 9PT, UK.

View Article

Download full-text PDF

Source
http://biochemj.org/lookup/doi/10.1042/BJ20041389
Publisher Site
http://dx.doi.org/10.1042/BJ20041389DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1134938PMC
April 2005

Newcomers in the process of mitochondrial permeabilization.

J Cell Sci 2005 Feb;118(Pt 3):473-83

Department of Cell Biology, University of Geneva, 30 Quai Ernest-Ansermet, 1211 Geneva 4, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1242/jcs.01654DOI Listing
February 2005

Bax does not directly participate in the Ca(2+)-induced permeability transition of isolated mitochondria.

J Biol Chem 2004 Sep 30;279(36):37415-22. Epub 2004 Jun 30.

CNR Institute of Neuroscience, Biomembranes Section and Department of Biomedical Sciences, University of Padova, Padova, Italy.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M314093200DOI Listing
September 2004

Apoptosis: bombarding the mitochondria.

Essays Biochem 2003 ;39:41-51

Department of Cell Biology, University of Geneva, 30 quai Ansermet, 1211 Geneva 4, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1042/bse0390041DOI Listing
July 2004

An anti-apoptotic viral protein that recruits Bax to mitochondria.

J Biol Chem 2004 May 5;279(21):22605-14. Epub 2004 Mar 5.

Centre National de la Recherche Scientifique, UMR 8125, Institut Gustave Roussy, 39 rue Camille-Desmoulins, F-94805 Villejuif, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M308408200DOI Listing
May 2004

Ca(2+) homeostasis during mitochondrial fragmentation and perinuclear clustering induced by hFis1.

J Biol Chem 2004 May 15;279(21):22704-14. Epub 2004 Mar 15.

Department of Physiology, University of Geneva Medical Center, Geneva 4, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M312366200DOI Listing
May 2004

Role of mitochondrial membrane permeabilization in apoptosis and cancer.

Oncogene 2004 Apr;23(16):2850-60

Cellular and Molecular Pharmacology Group, The Paterson Institute for Cancer Research, Wilmslow Road M20 4BX, Manchester, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/sj.onc.1207534DOI Listing
April 2004

Fatty acids enhance membrane permeabilization by pro-apoptotic Bax.

Biochem J 2004 Jan;377(Pt 2):509-16

Department of Biochemistry, McMaster University Health Sciences Centre, Hamilton, ON, Canada L8N 3Z5.

View Article

Download full-text PDF

Source
http://biochemj.org/lookup/doi/10.1042/bj20030938
Publisher Site
http://dx.doi.org/10.1042/BJ20030938DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1223875PMC
January 2004

Transbilayer lipid diffusion promoted by Bax: implications for apoptosis.

Biochemistry 2003 Dec;42(49):14576-82

Department of Biochemistry, McMaster University Health Sciences Centre, Hamilton, Ontario L8N 3Z5, Canada.

View Article

Download full-text PDF

Source
http://pubs.acs.org/doi/abs/10.1021/bi035348w
Publisher Site
http://dx.doi.org/10.1021/bi035348wDOI Listing
December 2003

Proteomic analysis of the mouse liver mitochondrial inner membrane.

J Biol Chem 2003 Oct 15;278(42):41566-71. Epub 2003 Jul 15.

University of Geneva, Department of Cellular Biology, 30 quai E Ansermet, 1205 Geneva, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M304940200DOI Listing
October 2003

hFis1, a novel component of the mammalian mitochondrial fission machinery.

J Biol Chem 2003 Sep 3;278(38):36373-9. Epub 2003 Jun 3.

Department of Cell Biology, University of Geneva, Quai Ernest-Ansermet 30, 1211 Geneva, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M303758200DOI Listing
September 2003

A retention factor keeps death at bay.

Nat Cell Biol 2003 Apr;5(4):281-3

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ncb0403-281DOI Listing
April 2003

Fusion of mitochondria in mammalian cells is dependent on the mitochondrial inner membrane potential and independent of microtubules or actin.

FEBS Lett 2003 Mar;538(1-3):53-9

Department of Cell Biology, University of Geneva, Quai Ernest-Ansermet 30, Geneva, Switzerland

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0014-5793(03)00124-8DOI Listing
March 2003

Bax oligomerization in mitochondrial membranes requires tBid (caspase-8-cleaved Bid) and a mitochondrial protein.

Biochem J 2002 Dec;368(Pt 3):915-21

Departement de Biologie Cellulaire, University of Geneva, 30 quai E. Ansermet, 1211 Geneva 4, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1042/BJ20020972DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1223025PMC
December 2002

Mitochondrial release of apoptosis-inducing factor occurs downstream of cytochrome c release in response to several proapoptotic stimuli.

J Cell Biol 2002 Dec 16;159(6):923-9. Epub 2002 Dec 16.

EMI-U 9922 Institut National de la Santé et de la Recherche Medicale (INSERM)/Université Paris 7, IFR02, AP-HP, CHU Bichat, 75018 Paris, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1083/jcb.200207071DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173976PMC
December 2002

Membrane perturbations induced by the apoptotic Bax protein.

Biochem J 2002 Nov;367(Pt 3):849-55

Department of Biochemistry, McMaster University Health Sciences Centre, Hamilton, ON L8N 3Z5, Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1042/BJ20020986DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1222950PMC
November 2002

Direct evidence for membrane pore formation by the apoptotic protein Bax.

Biochem Biophys Res Commun 2002 Nov;298(5):744-9

Department of Biochemistry, McMaster University Health Sciences Centre, Hamilton, Ont., Canada.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0006-291x(02)02544-5DOI Listing
November 2002

The apoptotic protein tBid promotes leakage by altering membrane curvature.

J Biol Chem 2002 Sep 24;277(36):32632-9. Epub 2002 Jun 24.

Department of Biochemistry, McMaster University Health Sciences Centre, Hamilton, Ontario L8N 3Z5, Canada.

View Article

Download full-text PDF

Source
http://www.jbc.org/cgi/doi/10.1074/jbc.M202396200
Publisher Site
http://dx.doi.org/10.1074/jbc.M202396200DOI Listing
September 2002

Direct addition of BimL to mitochondria does not lead to cytochrome c release.

FEBS Lett 2002 Jul;522(1-3):29-34

Département de Biologie Cellulaire, Sciences III, 30 quai E. Ansermet, 1211 Genève 4, Switzerland.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/s0014-5793(02)02871-5DOI Listing
July 2002

Bid induces cytochrome c-impermeable Bax channels in liposomes.

Biochem J 2002 May;363(Pt 3):547-52

Département de Biologie Cellulaire, Sciences III, 30 quai Ernest-Ansermet, CH-1211 Geneva 4, Switzerland.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1222507PMC
http://dx.doi.org/10.1042/0264-6021:3630547DOI Listing
May 2002