Publications by authors named "Jean-Claude Marshall"

44Publications

Bioanalysis of adeno-associated virus gene therapy therapeutics: regulatory expectations.

Bioanalysis 2019 Nov 25;11(21):2011-2024. Epub 2019 Oct 25.

Pfizer, Inc., Biomedicine Design, 1 Burtt Rd, Andover, MA 01810, USA.

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http://dx.doi.org/10.4155/bio-2019-0135DOI Listing
November 2019

Identification of the caffeine to trimethyluric acid ratio as a dietary biomarker to characterise variability in cytochrome P450 3A activity.

Eur J Clin Pharmacol 2019 Sep 23;75(9):1211-1218. Epub 2019 May 23.

Department of Clinical Pharmacology, College of Medicine and Public Health, Flinders University, Bedford Park, Adelaide, SA, 5042, Australia.

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http://link.springer.com/10.1007/s00228-019-02682-5
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http://dx.doi.org/10.1007/s00228-019-02682-5DOI Listing
September 2019

Assessment of inter-racial variability in CYP3A4 activity and inducibility among healthy adult males of Caucasian and South Asian ancestries.

Eur J Clin Pharmacol 2018 Jul 23;74(7):913-920. Epub 2018 Mar 23.

College of Medicine and Public Health, Flinders University, Bedford Park, Adelaide, SA, 5042, Australia.

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http://link.springer.com/10.1007/s00228-018-2450-4
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http://dx.doi.org/10.1007/s00228-018-2450-4DOI Listing
July 2018

The role of ADME pharmacogenomics in early clinical trials: perspective of the Industry Pharmacogenomics Working Group (I-PWG).

Pharmacogenomics 2015 Dec 30;16(18):2055-67. Epub 2015 Nov 30.

Pfizer Inc., Worldwide Research & Development, Department of Pharmacokinetics, Dynamics & Metabolism, Eastern Point Road, Groton, CT 06340, USA.

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http://dx.doi.org/10.2217/pgs.15.141DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5558530PMC
December 2015

Nm23-h1 binds to gelsolin and inactivates its actin-severing capacity to promote tumor cell motility and metastasis.

Cancer Res 2013 Oct 12;73(19):5949-62. Epub 2013 Aug 12.

Authors' Affiliations: Women's Cancers Section, Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, Bethesda; and Laboratory of Proteomics and Analytical Technologies, Science Applications International Corporation-Frederick, Inc., Frederick National Laboratory for Cancer Research, Frederick, Maryland.

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http://dx.doi.org/10.1158/0008-5472.CAN-13-0368DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3825031PMC
October 2013

Effect of inhibition of the lysophosphatidic acid receptor 1 on metastasis and metastatic dormancy in breast cancer.

J Natl Cancer Inst 2012 Sep 21;104(17):1306-19. Epub 2012 Aug 21.

The Women's Cancers Section, Laboratory of Molecular Pharmacology, Center for Cancer Research, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1093/jnci/djs319DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3611817PMC
September 2012

Dipyridamole prevents triple-negative breast-cancer progression.

Clin Exp Metastasis 2013 Jan 4;30(1):47-68. Epub 2012 Jul 4.

Centro di Ingegneria Genetica Biotecnologie Avanzate, Via Gaetano Salvatore 486, 80145 Naples, Italy.

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http://dx.doi.org/10.1007/s10585-012-9506-0DOI Listing
January 2013

Protein-protein interactions: a mechanism regulating the anti-metastatic properties of Nm23-H1.

Naunyn Schmiedebergs Arch Pharmacol 2011 Oct 29;384(4-5):351-62. Epub 2011 Jun 29.

Women's Cancers Section, Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1007/s00210-011-0646-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6545597PMC
October 2011

The Nm23-H1 metastasis suppressor as a translational target.

Eur J Cancer 2010 May 19;46(7):1278-82. Epub 2010 Mar 19.

Women's Cancers Section, Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, 37 Convent Drive, Room 1122, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.ejca.2010.02.042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2858387PMC
May 2010

Expression profiling of formalin-fixed paraffin embedded primary human uveal melanomas using DASL matrices.

J Cancer Res Clin Oncol 2010 Apr 13;136(4):577-86. Epub 2009 Oct 13.

The Henry C. Witelson Ophthalmic Pathology Laboratory and Registry, McGill University Health Center, 3775 University St., Lyman Duff Building, Room 216, Montreal, QC, H3A 2B4, Canada.

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http://dx.doi.org/10.1007/s00432-009-0692-3DOI Listing
April 2010

Fine needle aspiration biopsy to reestablish cell culture in an animal model of uveal melanoma.

Arq Bras Oftalmol 2009 Jul-Aug;72(4):515-8

Henry C. Witelson Ocular Pathology Laboratory, Department of Ophthalmology, McGill University, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1590/s0004-27492009000400015DOI Listing
March 2010

SPARC is expressed in human uveal melanoma and its abrogation reduces tumor cell proliferation.

Anticancer Res 2009 Aug;29(8):3059-64

The Henry C. Witelson Ocular Pathology Laboratory, McGill University, Montreal, QC, H3A 2B4, Canada.

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August 2009

Altered gene and protein expression by Nm23-H1 in metastasis suppression.

Mol Cell Biochem 2009 Sep 5;329(1-2):141-8. Epub 2009 May 5.

Women's Cancers Section, Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, 37 Convent Drive, Room 1122, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1007/s11010-009-0124-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3514412PMC
September 2009

Clinical-translational strategies for the elevation of Nm23-H1 metastasis suppressor gene expression.

Mol Cell Biochem 2009 Sep 23;329(1-2):115-20. Epub 2009 Apr 23.

Women's Cancers Section, Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, Bethesda, MD, USA.

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http://dx.doi.org/10.1007/s11010-009-0116-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3501675PMC
September 2009

The effect of blue light exposure in an ocular melanoma animal model.

J Exp Clin Cancer Res 2009 Apr 7;28:48. Epub 2009 Apr 7.

The Henry C Witelson Ophthalmic Pathology Laboratory and Registry, McGill University Health Center, Montreal, PQ, Canada.

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http://dx.doi.org/10.1186/1756-9966-28-48DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2679718PMC
April 2009

The role of metastasis suppressor genes in metastatic dormancy.

APMIS 2008 Jul-Aug;116(7-8):586-601

Women's Cancers Section, Laboratory of Molecular Pharmacology, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1111/j.1600-0463.2008.01213.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508681PMC
November 2008

Expression of cyclooxygenase-2 in choroidal neovascular membranes from age-related macular degeneration patients.

Retina 2009 Feb;29(2):176-80

The Henry C. Witelson Ocular Pathology Laboratory and Registry, McGill University, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1097/IAE.0b013e3181884fa6DOI Listing
February 2009

Single-cell tumor dormancy model of uveal melanoma.

Clin Exp Metastasis 2008 12;25(5):509-16. Epub 2008 Mar 12.

The Henry C Witelson Ophthalmic Pathology Laboratory and Registry, McGill University Health Center, Montreal, QC, Canada.

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http://dx.doi.org/10.1007/s10585-008-9158-2DOI Listing
September 2008

Molecular pathways mediating liver metastasis in patients with uveal melanoma.

Clin Cancer Res 2008 Feb;14(4):951-6

Henry C. Witelson Ocular Pathology Laboratory, McGill University, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1158/1078-0432.CCR-06-2630DOI Listing
February 2008

Immunomagnetic isolation and in vitro expansion of human uveal melanoma cell lines.

Mol Vis 2008 Jan 10;14:50-5. Epub 2008 Jan 10.

The Henry C. Witelson Ophthalmic Pathology Laboratory and Registry, McGill University Health Center, Montreal, PQ, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2263013PMC
January 2008

Immune expression and inhibition of heat shock protein 90 in uveal melanoma.

Clin Cancer Res 2008 Feb;14(3):847-55

Department of Ophthalmology and Pathology, The McGill University Health Center and Henry C. Witelson Ocular Pathology Laboratory, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1158/1078-0432.CCR-07-0926DOI Listing
February 2008

The effects of a cyclooxygenase-2 (COX-2) expression and inhibition on human uveal melanoma cell proliferation and macrophage nitric oxide production.

J Carcinog 2007 Nov 27;6:17. Epub 2007 Nov 27.

The Henry C, Witelson Ocular Pathology Laboratory and Registry, McGill University, 3775 University Street, Lyman Duff Building, Room 216, Montreal, Quebec H3A 2B4, Canada.

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http://www.carcinogenesis.com/text.asp?2007/6/1/17/42156
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http://dx.doi.org/10.1186/1477-3163-6-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2222223PMC
November 2007

In vitro characterization and inhibition of the CXCR4/CXCL12 chemokine axis in human uveal melanoma cell lines.

Cancer Cell Int 2007 Nov 14;7:17. Epub 2007 Nov 14.

The Henry C, Witelson Ophthalmic Pathology Laboratory and Registry, McGill University Health Center, Montreal, PQ, Canada.

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http://dx.doi.org/10.1186/1475-2867-7-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2194662PMC
November 2007

Expression of nm23-H1 in uveal melanoma.

Melanoma Res 2007 Oct;17(5):284-90

McGill University/Henry C. Witelson Ocular Pathology Laboratory, McGill University, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1097/CMR.0b013e3282eeea5aDOI Listing
October 2007

Expression of C-kit in retinoblastoma: a potential therapeutic target.

Br J Ophthalmol 2007 Nov 25;91(11):1532-6. Epub 2007 Jun 25.

Department of Ophthalmology and Pathology, The McGill University Health Center & Henry C. Witelson Ocular Pathology Laboratory, Montreal, Canada.

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http://bjo.bmj.com/content/91/11/1532.full.pdf
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http://bjo.bmj.com/content/early/2007/06/25/bjo.2007.119651.
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http://bjo.bmj.com/cgi/doi/10.1136/bjo.2007.119651
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http://dx.doi.org/10.1136/bjo.2007.119651DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2095433PMC
November 2007

Transcriptional profiling of human uveal melanoma from cell lines to intraocular tumors to metastasis.

Clin Exp Metastasis 2007 9;24(5):353-62. Epub 2007 May 9.

The Henry C. Witelson Ocular Pathology Laboratory and Registry, McGill University, 3775 University Street, Lyman Duff Building, Room 216, Montreal, QC, Canada, H3A 2B4.

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http://dx.doi.org/10.1007/s10585-007-9072-zDOI Listing
October 2007

The use of a cyclooxygenase-2 inhibitor (Nepafenac) in an ocular and metastatic animal model of uveal melanoma.

Carcinogenesis 2007 Sep 13;28(9):2053-8. Epub 2007 Apr 13.

The Henry C. Witelson Ophthalmic Pathology Laboratory and Registry, McGill University Health Center, 3775 University Street, Lyman Duff Building, Room 216, Montreal, Quebec H3A 2B4, Canada.

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http://dx.doi.org/10.1093/carcin/bgm091DOI Listing
September 2007

Expression and migratory analysis of 5 human uveal melanoma cell lines for CXCL12, CXCL8, CXCL1, and HGF.

J Carcinog 2007 Jan 29;6. Epub 2007 Jan 29.

The Henry C. Witelson Ophthalmic Pathology Laboratory and Registry, McGill University Health Center, Montreal, PQ, Canada.

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http://dx.doi.org/10.1186/1477-3163-6-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1790892PMC
January 2007

Blue light exposure and uveal melanoma.

Ophthalmology 2006 Jun;113(6):1062.e1; author reply 1062

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http://dx.doi.org/10.1016/j.ophtha.2006.02.037DOI Listing
June 2006

Characterization of ocular and metastatic uveal melanoma in an animal model.

Invest Ophthalmol Vis Sci 2005 Dec;46(12):4376-82

Henry C. Witelson Ophthalmic Pathology Laboratory and Registry, McGill University Health Center, Montreal, Quebec, Canada.

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http://carcin.oxfordjournals.org/content/early/2007/04/13/ca
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http://iovs.arvojournals.org/article.aspx?doi=10.1167/iovs.0
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http://dx.doi.org/10.1167/iovs.04-1103DOI Listing
December 2005

The role of c-kit and imatinib mesylate in uveal melanoma.

J Carcinog 2005 Oct 19;4:19. Epub 2005 Oct 19.

Department of Ophthalmology, Federal University of São Paulo, São Paulo, Brazil.

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http://dx.doi.org/10.1186/1477-3163-4-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1282581PMC
October 2005

Cell proliferation profile of five human uveal melanoma cell lines of different metastatic potential.

Pathobiology 2004 ;71(5):241-5

The Henry C. Witelson Ocular Pathology Laboratory and Registry, McGill University, Montreal, Canada.

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http://dx.doi.org/10.1159/000080057DOI Listing
February 2005

Cytotoxic effects of violacein in human uveal melanoma cell lines.

Melanoma Res 2004 Oct;14(5):421-4

The Henry C. Witelson Ophthalmic Pathology Laboratory, McGill University Health Centre, Lyman Duff Building, 3775 University St., Room 216, H3A 2BA, Montreal, QC, Canada.

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http://dx.doi.org/10.1097/00008390-200410000-00014DOI Listing
October 2004

How in vitro techniques have increased our understanding of uveal melanoma cellular biology.

Can J Ophthalmol 2004 Jun;39(4):428-32

Henry C. Witelson Ophthalmic Pathology Laboratory and Registry, McGill University Health Centre, Montreal, Que.

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http://dx.doi.org/10.1016/s0008-4182(04)80015-2DOI Listing
June 2004

Macrophage-derived soluble factor enhances melanoma inhibitory activity expression by uveal melanoma cells in vitro.

Melanoma Res 2004 Apr;14(2):91-5

The Henry C. Witelson Ophthalmic Pathology Laboratory and Registry, McGill University Health Center, Lyman Duff Building, 3775 University Street, Room 216, Montreal, Quebec H3A 2B4, Canada.

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http://dx.doi.org/10.1097/00008390-200404000-00003DOI Listing
April 2004