Jean-Christophe Marine

Jean-Christophe Marine

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Jean-Christophe Marine

Jean-Christophe Marine

Publications by authors named "Jean-Christophe Marine"

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Dynamic reversal of random X-Chromosome inactivation during iPSC reprogramming.

Genome Res 2019 Oct 12;29(10):1659-1672. Epub 2019 Sep 12.

KU Leuven-University of Leuven, Department of Development and Regeneration, Leuven Stem Cell Institute, B-3000 Leuven, Belgium.

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http://dx.doi.org/10.1101/gr.249706.119DOI Listing
October 2019

Melanoma plasticity and phenotypic diversity: therapeutic barriers and opportunities.

Genes Dev 2019 Oct;33(19-20):1295-1318

Ludwig Institute for Cancer Research, Nuffield Department of Clinical Medicine, University of Oxford, Headington, Oxford OX3 7DQ, United Kingdom.

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http://dx.doi.org/10.1101/gad.329771.119DOI Listing
October 2019

Targeting the Sphingosine 1-Phosphate Axis Exerts Potent Antitumor Activity in BRAFi-Resistant Melanomas.

Mol Cancer Ther 2019 02 27;18(2):289-300. Epub 2018 Nov 27.

Université Fédérale de Toulouse Midi-Pyrénées, Université Toulouse III Paul-Sabatier, Inserm, Centre de Recherches en Cancérologie de Toulouse, Toulouse, France.

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http://dx.doi.org/10.1158/1535-7163.MCT-17-1141DOI Listing
February 2019

The Endosomal Protein CEMIP Links WNT Signaling to MEK1-ERK1/2 Activation in Selumetinib-Resistant Intestinal Organoids.

Cancer Res 2018 08 18;78(16):4533-4548. Epub 2018 Jun 18.

Interdisciplinary Cluster for Applied Genoproteomics (GIGA), GIGA-Molecular Biology of Diseases, University of Liege, CHU, Sart-Tilman, Liège, Belgium.

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http://dx.doi.org/10.1158/0008-5472.CAN-17-3149DOI Listing
August 2018

Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018.

Authors:
Lorenzo Galluzzi Ilio Vitale Stuart A Aaronson John M Abrams Dieter Adam Patrizia Agostinis Emad S Alnemri Lucia Altucci Ivano Amelio David W Andrews Margherita Annicchiarico-Petruzzelli Alexey V Antonov Eli Arama Eric H Baehrecke Nickolai A Barlev Nicolas G Bazan Francesca Bernassola Mathieu J M Bertrand Katiuscia Bianchi Mikhail V Blagosklonny Klas Blomgren Christoph Borner Patricia Boya Catherine Brenner Michelangelo Campanella Eleonora Candi Didac Carmona-Gutierrez Francesco Cecconi Francis K-M Chan Navdeep S Chandel Emily H Cheng Jerry E Chipuk John A Cidlowski Aaron Ciechanover Gerald M Cohen Marcus Conrad Juan R Cubillos-Ruiz Peter E Czabotar Vincenzo D'Angiolella Ted M Dawson Valina L Dawson Vincenzo De Laurenzi Ruggero De Maria Klaus-Michael Debatin Ralph J DeBerardinis Mohanish Deshmukh Nicola Di Daniele Francesco Di Virgilio Vishva M Dixit Scott J Dixon Colin S Duckett Brian D Dynlacht Wafik S El-Deiry John W Elrod Gian Maria Fimia Simone Fulda Ana J García-Sáez Abhishek D Garg Carmen Garrido Evripidis Gavathiotis Pierre Golstein Eyal Gottlieb Douglas R Green Lloyd A Greene Hinrich Gronemeyer Atan Gross Gyorgy Hajnoczky J Marie Hardwick Isaac S Harris Michael O Hengartner Claudio Hetz Hidenori Ichijo Marja Jäättelä Bertrand Joseph Philipp J Jost Philippe P Juin William J Kaiser Michael Karin Thomas Kaufmann Oliver Kepp Adi Kimchi Richard N Kitsis Daniel J Klionsky Richard A Knight Sharad Kumar Sam W Lee John J Lemasters Beth Levine Andreas Linkermann Stuart A Lipton Richard A Lockshin Carlos López-Otín Scott W Lowe Tom Luedde Enrico Lugli Marion MacFarlane Frank Madeo Michal Malewicz Walter Malorni Gwenola Manic Jean-Christophe Marine Seamus J Martin Jean-Claude Martinou Jan Paul Medema Patrick Mehlen Pascal Meier Sonia Melino Edward A Miao Jeffery D Molkentin Ute M Moll Cristina Muñoz-Pinedo Shigekazu Nagata Gabriel Nuñez Andrew Oberst Moshe Oren Michael Overholtzer Michele Pagano Theocharis Panaretakis Manolis Pasparakis Josef M Penninger David M Pereira Shazib Pervaiz Marcus E Peter Mauro Piacentini Paolo Pinton Jochen H M Prehn Hamsa Puthalakath Gabriel A Rabinovich Markus Rehm Rosario Rizzuto Cecilia M P Rodrigues David C Rubinsztein Thomas Rudel Kevin M Ryan Emre Sayan Luca Scorrano Feng Shao Yufang Shi John Silke Hans-Uwe Simon Antonella Sistigu Brent R Stockwell Andreas Strasser Gyorgy Szabadkai Stephen W G Tait Daolin Tang Nektarios Tavernarakis Andrew Thorburn Yoshihide Tsujimoto Boris Turk Tom Vanden Berghe Peter Vandenabeele Matthew G Vander Heiden Andreas Villunger Herbert W Virgin Karen H Vousden Domagoj Vucic Erwin F Wagner Henning Walczak David Wallach Ying Wang James A Wells Will Wood Junying Yuan Zahra Zakeri Boris Zhivotovsky Laurence Zitvogel Gerry Melino Guido Kroemer

Cell Death Differ 2018 03 23;25(3):486-541. Epub 2018 Jan 23.

Paris Descartes/Paris V University, Paris, France.

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http://dx.doi.org/10.1038/s41418-017-0012-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5864239PMC
March 2018

Mouse Cutaneous Melanoma Induced by Mutant BRaf Arises from Expansion and Dedifferentiation of Mature Pigmented Melanocytes.

Cell Stem Cell 2017 Nov 12;21(5):679-693.e6. Epub 2017 Oct 12.

Laboratory for Molecular Cancer Biology, VIB Center for Cancer Biology, VIB, 3000 Leuven, Belgium; Laboratory for Molecular Cancer Biology, Department of Oncology, KULeuven, 3000 Leuven, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2017.08.003DOI Listing
November 2017

Translation rewiring at the heart of phenotype switching in melanoma.

Pigment Cell Melanoma Res 2017 05 20;30(3):282-283. Epub 2017 Apr 20.

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http://dx.doi.org/10.1111/pcmr.12583DOI Listing
May 2017

Non-coding RNAs: the dark side of nuclear-mitochondrial communication.

EMBO J 2017 05 17;36(9):1123-1133. Epub 2017 Mar 17.

Laboratory for Molecular Cancer Biology, Department of Oncology, KU Leuven, Leuven, Belgium

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http://dx.doi.org/10.15252/embj.201695546DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5412819PMC
May 2017

NEAT1-containing paraspeckles: Central hubs in stress response and tumor formation.

Cell Cycle 2017 01 4;16(2):137-138. Epub 2016 Oct 4.

a Laboratory for Molecular Cancer Biology, Center for the Biology of Disease, VIB , Leuven , Belgium.

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http://dx.doi.org/10.1080/15384101.2016.1235847DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5388437PMC
January 2017

The emerging role of long non-coding RNAs in cutaneous melanoma.

Pigment Cell Melanoma Res 2016 11 19;29(6):619-626. Epub 2016 Oct 19.

Department of Biology and Biochemistry, University of Bath, Bath, UK.

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http://dx.doi.org/10.1111/pcmr.12537DOI Listing
November 2016

Loss of oocytes due to conditional ablation of Murine double minute 2 (Mdm2) gene is p53-dependent and results in female sterility.

FEBS Lett 2016 08 18;590(16):2566-74. Epub 2016 Jul 18.

INRA, UMR85 Physiologie de la Reproduction et des Comportements, Nouzilly, France.

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http://dx.doi.org/10.1002/1873-3468.12275DOI Listing
August 2016

MDMX (MDM4), a Promising Target for p53 Reactivation Therapy and Beyond.

Cold Spring Harb Perspect Med 2016 07 1;6(7). Epub 2016 Jul 1.

Department of Molecular Cell Biology, Leiden University Medical Center, 2300 RA Leiden, The Netherlands.

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http://dx.doi.org/10.1101/cshperspect.a026237DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4930919PMC
July 2016

Regulation of Melanoma Progression through the TCF4/miR-125b/NEDD9 Cascade.

J Invest Dermatol 2016 06 9;136(6):1229-1237. Epub 2016 Mar 9.

Institut Curie, PSL Research University, INSERM U1021, Normal and Pathological Development of Melanocytes, Orsay, France; Université Paris-Sud, Université Paris-Saclay, CNRS UMR 3347, Orsay, France; Equipe Labellisée Ligue Contre le Cancer, Orsay, France. Electronic address:

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http://dx.doi.org/10.1016/j.jid.2016.02.803DOI Listing
June 2016

Chromatin-Bound MDM2 Regulates Serine Metabolism and Redox Homeostasis Independently of p53.

Mol Cell 2016 06 2;62(6):890-902. Epub 2016 Jun 2.

IRCM, Institut de Recherche en Cancérologie de Montpellier, 34298 Montpellier, France; INSERM, U1194, 34298 Montpellier, France; Université de Montpellier, 34298 Montpellier, France; Institut Régional du Cancer Montpellier, 34298 Montpellier, France. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2016.04.033DOI Listing
June 2016

Loss of autocrine endothelial-derived VEGF significantly reduces hemangiosarcoma development in conditional p53-deficient mice.

Cell Cycle 2014 11;13(9):1501-7. Epub 2014 Mar 11.

Vascular Cell Biology Unit; Department for Molecular Biomedical Research; VIB-Ghent University; Ghent, Belgium; Department of Biomedical Molecular Biology; Ghent University; Ghent, Belgium; Australian Centre for Blood Diseases; Monash University; Melbourne, Victoria, Australia.

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http://dx.doi.org/10.4161/cc.28474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050148PMC
April 2016

p53 Reactivation by PRIMA-1(Met) (APR-246) sensitises (V600E/K)BRAF melanoma to vemurafenib.

Eur J Cancer 2016 Mar 17;55:98-110. Epub 2016 Jan 17.

Laboratory of Oncology and Experimental Surgery, Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09598049150113
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http://dx.doi.org/10.1016/j.ejca.2015.12.002DOI Listing
March 2016

Novel Therapies for Metastatic Melanoma: An Update on Their Use in Older Patients.

Drugs Aging 2015 Oct;32(10):821-34

Department of General Medical Oncology, University Hospitals Leuven, Herestraat 49, 3000, Leuven, Belgium.

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http://dx.doi.org/10.1007/s40266-015-0304-7DOI Listing
October 2015

Different levels of Twist1 regulate skin tumor initiation, stemness, and progression.

Cell Stem Cell 2015 Jan;16(1):67-79

Université Libre de Buxelles (ULB), Institut de Recherche Interdisciplinaire en Biologie Humaine et Moléculaire (IRIBHM), 808 route de Lennik, 1070 Brussels, Belgium; WELBIO, 808 route de Lennik, 1070 Brussels, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.stem.2014.12.002DOI Listing
January 2015

The long noncoding RNA Neat1 is required for mammary gland development and lactation.

RNA 2014 Dec 14;20(12):1844-9. Epub 2014 Oct 14.

Center for the Biology of Disease, Laboratory for Molecular Cancer Biology, VIB, Leuven 3000, Belgium Center for Human Genetics, Laboratory for Molecular Cancer Biology, KULeuven, Leuven 3000, Belgium

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http://dx.doi.org/10.1261/rna.047332.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4238351PMC
December 2014

Chromatin remodelers HELLS and UHRF1 mediate the epigenetic deregulation of genes that drive retinoblastoma tumor progression.

Oncotarget 2014 Oct;5(20):9594-608

Department of Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, TN, USA. Department of Human Molecular Genetics and Biochemistry, Tel-Aviv University, Tel Aviv, Israel. Howard Hughes Medical Institute, Chevy Chase, MD, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4259422PMC
http://dx.doi.org/10.18632/oncotarget.2468DOI Listing
October 2014

The Xenopus doublesex-related gene Dmrt5 is required for olfactory placode neurogenesis.

Dev Biol 2013 Jan 9;373(1):39-52. Epub 2012 Oct 9.

Laboratoire de Génétique du Développement, Université Libre de Bruxelles, Institut de Biologie et de Médecine Moléculaires (IBMM), rue des Profs. Jeener et Brachet 12, B-6041 Gosselies, Belgium.

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http://dx.doi.org/10.1016/j.ydbio.2012.10.003DOI Listing
January 2013

TPT1/ TCTP-regulated pathways in phenotypic reprogramming.

Trends Cell Biol 2013 Jan 30;23(1):37-46. Epub 2012 Oct 30.

CNRS-UMR 8113, LBPA, École Normale Supérieure, 94235 Cachan, France.

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http://dx.doi.org/10.1016/j.tcb.2012.10.002DOI Listing
January 2013

MDM4 is a key therapeutic target in cutaneous melanoma.

Nat Med 2012 Aug 22;18(8):1239-47. Epub 2012 Jul 22.

Center for the Biology of Disease, Laboratory for Molecular Cancer Biology, Vlaams Instituut voor Biotechnologie (VIB), Leuven, Belgium; Center for Human Genetics, Katholieke Universiteit (KU) Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1038/nm.2863DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3744207PMC
August 2012

IGF2: the Achilles' heel of p53-deficiency?

EMBO Mol Med 2012 Aug 24;4(8):688-90. Epub 2012 Jul 24.

Laboratory for Molecular Cancer Biology, Center for the Biology of Disease, VIB-KULeuven, Leuven, Belgium.

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http://dx.doi.org/10.1002/emmm.201201509DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3494069PMC
August 2012

Spotlight on the role of COP1 in tumorigenesis.

Nat Rev Cancer 2012 Jun 7;12(7):455-64. Epub 2012 Jun 7.

Laboratory for Molecular Cancer Biology, VIB-KULeuven, O&N I Herestraat 49, Leuven, Belgium.

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http://dx.doi.org/10.1038/nrc3271DOI Listing
June 2012

Reciprocal repression between P53 and TCTP.

Nat Med 2011 Dec 11;18(1):91-9. Epub 2011 Dec 11.

Centre National de la Recherche Scientifique-Unité Mixte de Recherche 8113, Laboratoire de Biotechnologie et Pharmacologie génétique Appliquée, École Normale Supérieure, Cachan, France.

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http://www.nature.com/articles/nm.2546
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http://dx.doi.org/10.1038/nm.2546DOI Listing
December 2011

Functional analysis of the p53 pathway in neuroblastoma cells using the small-molecule MDM2 antagonist nutlin-3.

Mol Cancer Ther 2011 Jun 1;10(6):983-93. Epub 2011 Apr 1.

Center for Medical Genetics, Ghent University Hospital, De Pintelaan 185, B-9000 Ghent, Belgium.

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http://dx.doi.org/10.1158/1535-7163.MCT-10-1090DOI Listing
June 2011

MDM2 and MDMX in cancer and development.

Curr Top Dev Biol 2011 ;94:45-75

VIB–K.U.Leuven, Department of Molecular and Developmental Genetics, Laboratory for Molecular Cancer Biology, Leuven, Belgium.

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http://dx.doi.org/10.1016/B978-0-12-380916-2.00003-6DOI Listing
April 2011

Cop1 constitutively regulates c-Jun protein stability and functions as a tumor suppressor in mice.

J Clin Invest 2011 Apr 14;121(4):1329-43. Epub 2011 Mar 14.

Laboratory for Molecular Cancer Biology, Department of Molecular and Developmental Genetics, VIB-K.U.Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1172/JCI45784DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3070608PMC
April 2011

Widespread overexpression of epitope-tagged Mdm4 does not accelerate tumor formation in vivo.

Mol Cell Biol 2010 Nov 20;30(22):5394-405. Epub 2010 Sep 20.

Laboratory for Molecular Cancer Biology, Department of Biomedical Molecular Biology, VIB-UGent, Technologiepark, B-9052 Ghent, Belgium.

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http://dx.doi.org/10.1128/MCB.00330-10DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2976380PMC
November 2010

Pharmacological rescue of p53 in cancer therapy: widening the sensitive tumor spectrum by targeting MDMX.

Cancer Cell 2010 Nov;18(5):399-400

Laboratory For Molecular Cancer Biology, Department of Molecular and Developmental Genetics, VIB-KULeuven, O&N I Herestraat 49 - bus 602, B-3000 Leuven, Belgium.

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http://dx.doi.org/10.1016/j.ccr.2010.10.026DOI Listing
November 2010

Bcl-2 and accelerated DNA repair mediates resistance of hair follicle bulge stem cells to DNA-damage-induced cell death.

Nat Cell Biol 2010 Jun 16;12(6):572-82. Epub 2010 May 16.

Interdisciplinary Research Institute (IRIBHM), Université Libre de Bruxelles (ULB), 808, route de Lennik, BatC, C6-130, 1070 Brussels, Belgium.

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http://dx.doi.org/10.1038/ncb2059DOI Listing
June 2010

Journal club. A cancer geneticist looks at the link between small RNA molecules and cancer.

Nature 2010 Apr;464(7293):1249

VIB-Catholic University Leuven, Belgium.

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http://dx.doi.org/10.1038/4641249eDOI Listing
April 2010

Transforming growth factor-beta and mutant p53 conspire to induce metastasis by antagonizing p63: a (ternary) complex affair.

Breast Cancer Res 2009 27;11(4):304. Epub 2009 Jul 27.

Laboratory for Molecular Cancer Biology, VIB-UGent, Technologiepark, 927, B-9052 Ghent, Belgium.

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http://breast-cancer-research.biomedcentral.com/articles/10.
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http://dx.doi.org/10.1186/bcr2337DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2750109PMC
February 2010

c-Abl phosphorylates Hdmx and regulates its interaction with p53.

J Biol Chem 2009 Feb 15;284(6):4031-9. Epub 2008 Dec 15.

Lautenberg Center for General and Tumor Immunology, The Hebrew University Hadassah Medical School, Jerusalem 91120, Israel.

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http://dx.doi.org/10.1074/jbc.M809211200DOI Listing
February 2009

Mdm2 exerts pro-apoptotic activities by antagonizing insulin-like growth factor-I-mediated survival.

Cell Cycle 2008 Oct 18;7(19):3098-103. Epub 2008 Oct 18.

Laboratory for Molecular Cancer Biology, VIB-UGent, Gent, Belgium.

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http://dx.doi.org/10.4161/cc.7.19.6807DOI Listing
October 2008

Regulation of SIRT6 protein levels by nutrient availability.

FEBS Lett 2008 Mar 31;582(5):543-8. Epub 2008 Jan 31.

The Mina and Everard Goodman Faculty of Life Sciences, Bar-Ilan University, Ramat-Gan, Israel.

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http://dx.doi.org/10.1016/j.febslet.2008.01.019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3263697PMC
March 2008

A critical role for p53 in the control of NF-kappaB-dependent gene expression in TLR4-stimulated dendritic cells exposed to Genistein.

J Immunol 2007 Apr;178(8):5048-57

Laboratory for Eukaryotic Gene Expression and Signal Transduction (LEGEST), Molecular Biology, Ghent University, Ghent, Belgium.

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http://dx.doi.org/10.4049/jimmunol.178.8.5048DOI Listing
April 2007

Distinct roles of Mdm2 and Mdm4 in red cell production.

Blood 2007 Mar 14;109(6):2630-3. Epub 2006 Nov 14.

Laboratory for Molecular Cancer Biology, Flanders Institute for Biotechnology (VIB), University of Ghent, Belgium.

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http://dx.doi.org/10.1182/blood-2006-03-013656DOI Listing
March 2007

MDMX: from bench to bedside.

J Cell Sci 2007 Feb;120(Pt 3):371-8

Laboratory For Molecular Cancer Biology, Flanders Interuniversity Institute for Biotechnology (VIB), University of Ghent, B-9052 Ghent, Belgium.

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http://dx.doi.org/10.1242/jcs.03362DOI Listing
February 2007

Evolutionarily conserved role of nucleostemin: controlling proliferation of stem/progenitor cells during early vertebrate development.

Mol Cell Biol 2006 Dec 25;26(24):9291-301. Epub 2006 Sep 25.

Laboratory for Molecular Cancer Biology, Flanders Interuniversity Institute for Biotechnology (VIB), Technologiepark, 927, B-9052 Ghent, Belgium.

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http://dx.doi.org/10.1128/MCB.01183-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1698517PMC
December 2006

Evi1 is specifically expressed in the distal tubule and duct of the Xenopus pronephros and plays a role in its formation.

Dev Biol 2006 Jun 30;294(1):203-19. Epub 2006 Mar 30.

Laboratoire d'Embryologie Moléculaire, Université Libre de Bruxelles, Institut de Biologie et de Médecine Moléculaires (IBMM), rue des Profs. Jeener et Brachet 12, B-6041 Gosselies, Belgium.

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http://dx.doi.org/10.1016/j.ydbio.2006.02.040DOI Listing
June 2006

Mdm4 and Mdm2 cooperate to inhibit p53 activity in proliferating and quiescent cells in vivo.

Proc Natl Acad Sci U S A 2006 Feb 21;103(9):3232-7. Epub 2006 Feb 21.

Laboratory for Molecular Cancer Biology, Flanders Interuniversity Institute for Biotechnology, University of Ghent, Belgium.

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http://dx.doi.org/10.1073/pnas.0508476103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1413884PMC
February 2006

PTPRV is a key mediator of p53-induced cell cycle exit.

Cell Cycle 2005 Dec 26;4(12):1703-5. Epub 2005 Dec 26.

Laboratory For Molecular Cancer Biology, Flanders Interuniversity Institute for Biotechnology (VIB), Ghent University, Ghent, Belgium.

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https://www.tandfonline.com/doi/full/10.4161/cc.4.12.2207
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http://dx.doi.org/10.4161/cc.4.12.2207DOI Listing
December 2005

Mdmx as an essential regulator of p53 activity.

Biochem Biophys Res Commun 2005 Jun;331(3):750-60

Laboratory For Molecular Cancer Biology, Flanders Interuniversity Institute for Biotechnology (VIB), B-9052 Ghent, Belgium.

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http://linkinghub.elsevier.com/retrieve/pii/S0006291X0500657
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http://dx.doi.org/10.1016/j.bbrc.2005.03.151DOI Listing
June 2005

dapk1, encoding an activator of a p19ARF-p53-mediated apoptotic checkpoint, is a transcription target of p53.

Oncogene 2005 Feb;24(8):1461-6

Laboratory for Molecular Cancer Biology, Flanders Interuniversity Institute for Biotechnology (VIB), Technologiepark, 927, Ghent B-9052, Belgium.

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http://dx.doi.org/10.1038/sj.onc.1208256DOI Listing
February 2005

Direct regulation of the Nrarp gene promoter by the Notch signaling pathway.

Biochem Biophys Res Commun 2004 Sep;322(2):526-34

Laboratoire d'Embryologie Moléculaire, Université Libre de Bruxelles, Institut de Biologie et de Médecine Moléculaires, rue des Profs. Jeener et Brachet 12, B-6041 Gosselies, Belgium.

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http://dx.doi.org/10.1016/j.bbrc.2004.07.157DOI Listing
September 2004

Mdmx and Mdm2: brothers in arms?

Cell Cycle 2004 Jul 2;3(7):900-4. Epub 2004 Jul 2.

Laboratory For Molecular Cancer Biology, Flanders Interuniversity Institute for Biotechnology (VIB), Ghent, Belgium.

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July 2004

Critical role for a central part of Mdm2 in the ubiquitylation of p53.

Mol Cell Biol 2003 Jul;23(14):4929-38

Department of Molecular and Cell Biology and Center for Biomedical Genetics, Leiden University Medical Center, 2300 RA Leiden, The Netherlands.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC162227PMC
http://dx.doi.org/10.1128/mcb.23.14.4929-4938.2003DOI Listing
July 2003

Nucleophosmin regulates the stability and transcriptional activity of p53.

Nat Cell Biol 2002 Jul;4(7):529-33

European Institute of Oncology, Department of Experimental Oncology, Via Ripamonti 435, 20141 Milan, Italy.

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http://www.nature.com/articles/ncb814
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http://dx.doi.org/10.1038/ncb814DOI Listing
July 2002

Hdmx recruitment into the nucleus by Hdm2 is essential for its ability to regulate p53 stability and transactivation.

J Biol Chem 2002 Mar 13;277(9):7318-23. Epub 2001 Dec 13.

Department of Experimental Oncology, European Institute of Oncology, 435 Via Ripamonti, 20141 Milan, Italy.

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http://dx.doi.org/10.1074/jbc.M108795200DOI Listing
March 2002