Jean-Baptiste Cazier

Jean-Baptiste Cazier

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Jean-Baptiste Cazier

Jean-Baptiste Cazier

Publications by authors named "Jean-Baptiste Cazier"

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72Publications

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External Replication of Urinary Bladder Cancer Prognostic Polymorphisms in the UK Biobank.

Front Oncol 2019 18;9:1082. Epub 2019 Oct 18.

Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, United Kingdom.

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http://dx.doi.org/10.3389/fonc.2019.01082DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813571PMC
October 2019

Genetic susceptibility to radiation-related thyroid cancer: a systematic review.

Endocr Relat Cancer 2019 Sep 1. Epub 2019 Sep 1.

F de Vathaire, Cancer and radiation , Research Centre on Epidemiology and Population Health, Villejuif, France.

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http://dx.doi.org/10.1530/ERC-19-0321DOI Listing
September 2019

Conserved properties of genetic architecture of renal and fat transcriptomes in rat models of insulin resistance.

Dis Model Mech 2019 07 15;12(7). Epub 2019 Jul 15.

The Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Headington, Oxford OX3 7BN, United Kingdom

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http://dx.doi.org/10.1242/dmm.038539DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6679378PMC
July 2019

Genome-wide Association Study for Tumour Stage, Grade, Size, and Age at Diagnosis of Non-muscle-invasive Bladder Cancer.

Eur Urol Oncol 2019 Jul 15;2(4):381-389. Epub 2018 Sep 15.

Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK; Department of Complex Genetics, Maastricht University, The Netherlands.

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http://dx.doi.org/10.1016/j.euo.2018.08.020DOI Listing
July 2019

Novel putative drugs and key initiating genes for neurodegenerative disease determined using network-based genetic integrative analysis.

J Cell Biochem 2019 Apr 9;120(4):5459-5471. Epub 2018 Oct 9.

Laboratory of Systems Biology and Bioinformatics (LBB), Institute of Biochemistry and Biophysics, University of Tehran, Tehran, Iran.

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http://doi.wiley.com/10.1002/jcb.27825
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http://dx.doi.org/10.1002/jcb.27825DOI Listing
April 2019

Association between loss of Y chromosome and poor prognosis in male head and neck squamous cell carcinoma.

Head Neck 2019 Apr 23;41(4):993-1006. Epub 2018 Dec 23.

Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, United Kingdom.

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http://dx.doi.org/10.1002/hed.25537DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6492017PMC
April 2019

Candidate gene variant effects on language disorders in Robinson Crusoe Island.

Ann Hum Biol 2019 Mar 19;46(2):109-119. Epub 2019 Jun 19.

a Department of Biological and Medical Sciences, Faculty of Health and Life Sciences , Oxford Brookes University , Oxford , UK.

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https://www.tandfonline.com/doi/full/10.1080/03014460.2019.1
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http://dx.doi.org/10.1080/03014460.2019.1622776DOI Listing
March 2019

Molecular genetics of the transcription factor GLIS3 identifies its dual function in beta cells and neurons.

Genomics 2018 03 11;110(2):98-111. Epub 2017 Sep 11.

Sorbonne Universities, University Pierre & Marie Curie, University Paris Descartes, Sorbonne Paris Cité, INSERM UMR_S1138, Cordeliers Research Centre, Paris, France; The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom; McGill University and Genome Quebec Innovation Centre, 740 Doctor Penfield Avenue, Montreal, QC H3A 0G1, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ygeno.2017.09.001DOI Listing
March 2018

Harnessing genomics to improve outcomes for women with cancer in India: key priorities for research.

Lancet Oncol 2018 02;19(2):e102-e112

Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, UK; Centre for Computational Biology, University of Birmingham, Birmingham, UK.

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http://dx.doi.org/10.1016/S1470-2045(17)30726-XDOI Listing
February 2018

Association of coronary artery disease and chronic kidney disease in Lebanese population.

Int J Clin Exp Med 2015 15;8(9):15866-77. Epub 2015 Sep 15.

School of Medicine, Lebanese University Beirut, Lebanon ; Division of Nephrology, Department of Internal Medicine, Rafik Hariri University Hospital Beirut, Lebanon.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4658979PMC
December 2015

Application of whole genome and RNA sequencing to investigate the genomic landscape of common variable immunodeficiency disorders.

Clin Immunol 2015 Oct 26;160(2):301-14. Epub 2015 Jun 26.

Nuffield Department of Medicine, University of Oxford, Oxford, UK; Oxford NIHR Biomedical Research Centre, John Radcliffe Hospital, Oxford, UK. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2015.05.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601528PMC
October 2015

Factors influencing success of clinical genome sequencing across a broad spectrum of disorders.

Authors:
Jenny C Taylor Hilary C Martin Stefano Lise John Broxholme Jean-Baptiste Cazier Andy Rimmer Alexander Kanapin Gerton Lunter Simon Fiddy Chris Allan A Radu Aricescu Moustafa Attar Christian Babbs Jennifer Becq David Beeson Celeste Bento Patricia Bignell Edward Blair Veronica J Buckle Katherine Bull Ondrej Cais Holger Cario Helen Chapel Richard R Copley Richard Cornall Jude Craft Karin Dahan Emma E Davenport Calliope Dendrou Olivier Devuyst Aimée L Fenwick Jonathan Flint Lars Fugger Rodney D Gilbert Anne Goriely Angie Green Ingo H Greger Russell Grocock Anja V Gruszczyk Robert Hastings Edouard Hatton Doug Higgs Adrian Hill Chris Holmes Malcolm Howard Linda Hughes Peter Humburg David Johnson Fredrik Karpe Zoya Kingsbury Usha Kini Julian C Knight Jonathan Krohn Sarah Lamble Craig Langman Lorne Lonie Joshua Luck Davis McCarthy Simon J McGowan Mary Frances McMullin Kerry A Miller Lisa Murray Andrea H Németh M Andrew Nesbit David Nutt Elizabeth Ormondroyd Annette Bang Oturai Alistair Pagnamenta Smita Y Patel Melanie Percy Nayia Petousi Paolo Piazza Sian E Piret Guadalupe Polanco-Echeverry Niko Popitsch Fiona Powrie Chris Pugh Lynn Quek Peter A Robbins Kathryn Robson Alexandra Russo Natasha Sahgal Pauline A van Schouwenburg Anna Schuh Earl Silverman Alison Simmons Per Soelberg Sørensen Elizabeth Sweeney John Taylor Rajesh V Thakker Ian Tomlinson Amy Trebes Stephen Rf Twigg Holm H Uhlig Paresh Vyas Tim Vyse Steven A Wall Hugh Watkins Michael P Whyte Lorna Witty Ben Wright Chris Yau David Buck Sean Humphray Peter J Ratcliffe John I Bell Andrew Om Wilkie David Bentley Peter Donnelly Gilean McVean

Nat Genet 2015 Jul 18;47(7):717-726. Epub 2015 May 18.

Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1038/ng.3304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4601524PMC
July 2015

mQTL.NMR: an integrated suite for genetic mapping of quantitative variations of (1)H NMR-based metabolic profiles.

Anal Chem 2015 Apr 2;87(8):4377-84. Epub 2015 Apr 2.

∥Department of Oncology, University of Oxford, Roosevelt Drive, Oxford OX3 7DQ, U.K.

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http://pubs.acs.org/doi/10.1021/acs.analchem.5b00145
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http://dx.doi.org/10.1021/acs.analchem.5b00145DOI Listing
April 2015

Imaging DNA damage allows detection of preneoplasia in the BALB-neuT model of breast cancer.

J Nucl Med 2014 Dec 13;55(12):2026-31. Epub 2014 Nov 13.

Department of Oncology, CRUK/MRC Oxford Institute for Radiation Oncology, Oxford University, Oxford, United Kingdom

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http://jnm.snmjournals.org/cgi/doi/10.2967/jnumed.114.142083
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http://dx.doi.org/10.2967/jnumed.114.142083DOI Listing
December 2014

Choice of transcripts and software has a large effect on variant annotation.

Genome Med 2014 31;6(3):26. Epub 2014 Mar 31.

Department of Statistics, University of Oxford, South Parks Road, Oxford, UK ; Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford, UK.

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http://dx.doi.org/10.1186/gm543DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4062061PMC
June 2014

Large-scale association analysis identifies new risk loci for coronary artery disease.

Authors:
Panos Deloukas Stavroula Kanoni Christina Willenborg Martin Farrall Themistocles L Assimes John R Thompson Erik Ingelsson Danish Saleheen Jeanette Erdmann Benjamin A Goldstein Kathleen Stirrups Inke R König Jean-Baptiste Cazier Asa Johansson Alistair S Hall Jong-Young Lee Cristen J Willer John C Chambers Tõnu Esko Lasse Folkersen Anuj Goel Elin Grundberg Aki S Havulinna Weang K Ho Jemma C Hopewell Niclas Eriksson Marcus E Kleber Kati Kristiansson Per Lundmark Leo-Pekka Lyytikäinen Suzanne Rafelt Dmitry Shungin Rona J Strawbridge Gudmar Thorleifsson Emmi Tikkanen Natalie Van Zuydam Benjamin F Voight Lindsay L Waite Weihua Zhang Andreas Ziegler Devin Absher David Altshuler Anthony J Balmforth Inês Barroso Peter S Braund Christof Burgdorf Simone Claudi-Boehm David Cox Maria Dimitriou Ron Do Alex S F Doney NourEddine El Mokhtari Per Eriksson Krista Fischer Pierre Fontanillas Anders Franco-Cereceda Bruna Gigante Leif Groop Stefan Gustafsson Jörg Hager Göran Hallmans Bok-Ghee Han Sarah E Hunt Hyun M Kang Thomas Illig Thorsten Kessler Joshua W Knowles Genovefa Kolovou Johanna Kuusisto Claudia Langenberg Cordelia Langford Karin Leander Marja-Liisa Lokki Anders Lundmark Mark I McCarthy Christa Meisinger Olle Melander Evelin Mihailov Seraya Maouche Andrew D Morris Martina Müller-Nurasyid Kjell Nikus John F Peden N William Rayner Asif Rasheed Silke Rosinger Diana Rubin Moritz P Rumpf Arne Schäfer Mohan Sivananthan Ci Song Alexandre F R Stewart Sian-Tsung Tan Gudmundur Thorgeirsson C Ellen van der Schoot Peter J Wagner George A Wells Philipp S Wild Tsun-Po Yang Philippe Amouyel Dominique Arveiler Hanneke Basart Michael Boehnke Eric Boerwinkle Paolo Brambilla Francois Cambien Adrienne L Cupples Ulf de Faire Abbas Dehghan Patrick Diemert Stephen E Epstein Alun Evans Marco M Ferrario Jean Ferrières Dominique Gauguier Alan S Go Alison H Goodall Villi Gudnason Stanley L Hazen Hilma Holm Carlos Iribarren Yangsoo Jang Mika Kähönen Frank Kee Hyo-Soo Kim Norman Klopp Wolfgang Koenig Wolfgang Kratzer Kari Kuulasmaa Markku Laakso Reijo Laaksonen Ji-Young Lee Lars Lind Willem H Ouwehand Sarah Parish Jeong E Park Nancy L Pedersen Annette Peters Thomas Quertermous Daniel J Rader Veikko Salomaa Eric Schadt Svati H Shah Juha Sinisalo Klaus Stark Kari Stefansson David-Alexandre Trégouët Jarmo Virtamo Lars Wallentin Nicholas Wareham Martina E Zimmermann Markku S Nieminen Christian Hengstenberg Manjinder S Sandhu Tomi Pastinen Ann-Christine Syvänen G Kees Hovingh George Dedoussis Paul W Franks Terho Lehtimäki Andres Metspalu Pierre A Zalloua Agneta Siegbahn Stefan Schreiber Samuli Ripatti Stefan S Blankenberg Markus Perola Robert Clarke Bernhard O Boehm Christopher O'Donnell Muredach P Reilly Winfried März Rory Collins Sekar Kathiresan Anders Hamsten Jaspal S Kooner Unnur Thorsteinsdottir John Danesh Colin N A Palmer Robert Roberts Hugh Watkins Heribert Schunkert Nilesh J Samani

Nat Genet 2013 Jan 2;45(1):25-33. Epub 2012 Dec 2.

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http://dx.doi.org/10.1038/ng.2480DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3679547PMC
January 2013

Analysis of colorectal cancers in British Bangladeshi identifies early onset, frequent mucinous histotype and a high prevalence of RBFOX1 deletion.

Mol Cancer 2013 Jan 3;12. Epub 2013 Jan 3.

Centre for Digestive Diseases, Blizard Institute of Cell and Molecular Science, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, 4 Newark St, Whitechapel, London, E1 2AT, UK.

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http://dx.doi.org/10.1186/1476-4598-12-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3544714PMC
January 2013

Multiple segmental uniparental disomy associated with abnormal DNA methylation of imprinted Loci in silver-russell syndrome.

J Clin Endocrinol Metab 2012 Nov 31;97(11):E2188-93. Epub 2012 Aug 31.

Centre for Endocrinology, William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Charterhouse Square, London EC1M 6BQ, United kingdom.

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http://dx.doi.org/10.1210/jc.2012-1980DOI Listing
November 2012

GREVE: Genomic Recurrent Event ViEwer to assist the identification of patterns across individual cancer samples.

Bioinformatics 2012 Nov 8;28(22):2981-2. Epub 2012 Sep 8.

Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, OX3 7BN and Department of Statistics, University of Oxford, 1 South Parks Road, OX1 3TG, Oxford, UK.

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http://dx.doi.org/10.1093/bioinformatics/bts547DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3496338PMC
November 2012

Common variants at the MHC locus and at chromosome 16q24.1 predispose to Barrett's esophagus.

Authors:
Zhan Su Laura J Gay Amy Strange Claire Palles Gavin Band David C Whiteman Francesco Lescai Cordelia Langford Manoj Nanji Sarah Edkins Anouk van der Winkel David Levine Peter Sasieni Céline Bellenguez Kimberley Howarth Colin Freeman Nigel Trudgill Art T Tucker Matti Pirinen Maikel P Peppelenbosch Luc J W van der Laan Ernst J Kuipers Joost P H Drenth Wilbert H Peters John V Reynolds Dermot P Kelleher Ross McManus Heike Grabsch Hans Prenen Raf Bisschops Kausila Krishnadath Peter D Siersema Jantine W P M van Baal Mark Middleton Russell Petty Richard Gillies Nicola Burch Pradeep Bhandari Stuart Paterson Cathryn Edwards Ian Penman Kishor Vaidya Yeng Ang Iain Murray Praful Patel Weimin Ye Paul Mullins Anna H Wu Nigel C Bird Helen Dallal Nicholas J Shaheen Liam J Murray Konrad Koss Leslie Bernstein Yvonne Romero Laura J Hardie Rui Zhang Helen Winter Douglas A Corley Simon Panter Harvey A Risch Brian J Reid Ian Sargeant Marilie D Gammon Howard Smart Anjan Dhar Hugh McMurtry Haythem Ali Geoffrey Liu Alan G Casson Wong-Ho Chow Matt Rutter Ashref Tawil Danielle Morris Chuka Nwokolo Peter Isaacs Colin Rodgers Krish Ragunath Chris MacDonald Chris Haigh David Monk Gareth Davies Saj Wajed David Johnston Michael Gibbons Sue Cullen Nicholas Church Ruth Langley Michael Griffin Derek Alderson Panos Deloukas Sarah E Hunt Emma Gray Serge Dronov Simon C Potter Avazeh Tashakkori-Ghanbaria Mark Anderson Claire Brooks Jenefer M Blackwell Elvira Bramon Matthew A Brown Juan P Casas Aiden Corvin Audrey Duncanson Hugh S Markus Christopher G Mathew Colin N A Palmer Robert Plomin Anna Rautanen Stephen J Sawcer Richard C Trembath Ananth C Viswanathan Nicholas Wood Gosia Trynka Cisca Wijmenga Jean-Baptiste Cazier Paul Atherfold Anna M Nicholson Nichola L Gellatly Deborah Glancy Sheldon C Cooper David Cunningham Tore Lind Julie Hapeshi David Ferry Barrie Rathbone Julia Brown Sharon Love Stephen Attwood Stuart MacGregor Peter Watson Scott Sanders Weronica Ek Rebecca F Harrison Paul Moayyedi John de Caestecker Hugh Barr Elia Stupka Thomas L Vaughan Leena Peltonen Chris C A Spencer Ian Tomlinson Peter Donnelly Janusz A Z Jankowski

Nat Genet 2012 Oct 9;44(10):1131-6. Epub 2012 Sep 9.

Wellcome Trust Centre for Human Genetics, Oxford, UK.

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http://dx.doi.org/10.1038/ng.2408DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3459818PMC
October 2012

SNP rs6457327 in the HLA region on chromosome 6p is predictive of the transformation of follicular lymphoma.

Blood 2011 Mar 13;117(11):3147-50. Epub 2011 Jan 13.

Centre for Haemato-Oncology, Barts Cancer Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.

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http://dx.doi.org/10.1182/blood-2010-10-315382DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3062316PMC
March 2011

General lessons from large-scale studies to identify human cancer predisposition genes.

J Pathol 2010 Jan;220(2):255-62

Molecular and Population Genetics Laboratory, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK.

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http://dx.doi.org/10.1002/path.2650DOI Listing
January 2010

Colorectal cancer risk is not associated with increased levels of homozygosity in a population from the United Kingdom.

Cancer Res 2009 Sep 1;69(18):7422-9. Epub 2009 Sep 1.

The Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, United Kingdom.

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http://dx.doi.org/10.1158/0008-5472.CAN-09-0659DOI Listing
September 2009

Single nucleotide polymorphism array analysis defines a specific genetic fingerprint for well-differentiated cutaneous SCCs.

J Invest Dermatol 2009 Jun 8;129(6):1562-8. Epub 2009 Jan 8.

Cancer Research UK Skin Tumour Laboratory, ICMS, Barts and the London School of Medicine and Dentistry, Queen Mary, University of London, London, UK.

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http://linkinghub.elsevier.com/retrieve/pii/S0022202X1534351
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http://dx.doi.org/10.1038/jid.2008.408DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3042680PMC
June 2009

Common variation at the adiponectin locus is not associated with colorectal cancer risk in the UK.

Hum Mol Genet 2009 May 5;18(10):1889-92. Epub 2009 Mar 5.

Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1093/hmg/ddp109DOI Listing
May 2009

Novel regions of acquired uniparental disomy discovered in acute myeloid leukemia.

Genes Chromosomes Cancer 2008 Sep;47(9):729-39

Cancer Genomics Unit, Medical Oncology Centre, Barts and the London School of Medicine, Charterhouse Square, London EC1M 6BQ, UK.

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http://dx.doi.org/10.1002/gcc.20573DOI Listing
September 2008

Segmental uniparental disomy is a commonly acquired genetic event in relapsed acute myeloid leukemia.

Blood 2008 Aug 19;112(3):814-21. Epub 2008 May 19.

Medical Oncology Unit, Centre for Molecular Oncology, Institute of Cancer, Barts and the London School of Medicine and Dentistry, London, UK.

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http://dx.doi.org/10.1182/blood-2008-01-132431DOI Listing
August 2008

Identification of genomic changes associated with cisplatin resistance in testicular germ cell tumor cell lines.

Genes Chromosomes Cancer 2008 Jul;47(7):604-13

Medical Oncology Centre, Institute of Cancer, Barts and London School of Medicine and Dentistry, Queen Mary, University of London, London, UK.

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http://dx.doi.org/10.1002/gcc.20564DOI Listing
July 2008

A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3.

Nat Genet 2008 May 30;40(5):623-30. Epub 2008 Mar 30.

Molecular and Population Genetics Laboratory, London Research Institute, Cancer Research UK, London WC2A 3PX, UK.

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http://dx.doi.org/10.1038/ng.111DOI Listing
May 2008

Microdeletions are a general feature of adult and adolescent acute lymphoblastic leukemia: Unexpected similarities with pediatric disease.

Proc Natl Acad Sci U S A 2008 May 5;105(18):6708-13. Epub 2008 May 5.

Cancer Research UK Medical Oncology Centre, Barts and the London School of Medicine, Queen Mary College, London EC1M 6BQ, United Kingdom.

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http://dx.doi.org/10.1073/pnas.0800408105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2373322PMC
May 2008