Jean J Zhao

Oncogene 2020 Jan 28;39(1):50-63. Epub 2019 Aug 28.

Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, SC, 29425, USA.

JCI Insight 2019 May 23;5. Epub 2019 May 23.

Department of Medicine and.

J Clin Oncol 2019 Mar 4;37(9):741-750. Epub 2019 Feb 4.

1 Dana-Farber Cancer Institute, Boston, MA.

Curr Protoc Mol Biol 2019 01 22;125(1):e71. Epub 2018 Oct 22.

Dana-Farber Cancer Institute and Harvard Medical School, Boston, Massachusetts.

Sci Rep 2019 Jan 24;9(1):622. Epub 2019 Jan 24.

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, 02215, USA.

Cell Rep 2018 12;25(11):2972-2980.e5

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA; Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA. Electronic address:

Trends Cell Biol 2018 11 27;28(11):911-925. Epub 2018 Jul 27.

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA. Electronic address:

iScience 2018 Nov 18;9:149-160. Epub 2018 Oct 18.

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA; Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. Electronic address:

Proc Natl Acad Sci U S A 2018 10 17;115(40):E9325-E9332. Epub 2018 Sep 17.

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215;

J Med Chem 2018 10 27;61(19):8613-8624. Epub 2018 Sep 27.

College of Pharmaceutical Sciences , Zhejiang University , Hangzhou , Zhejiang 310058 , China.

Proc Natl Acad Sci U S A 2018 10 25;115(41):E9600-E9609. Epub 2018 Sep 25.

Department of Genetics, Harvard Medical School, Boston, MA 02115;

Elife 2018 07 30;7. Epub 2018 Jul 30.

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, United States.

Cancer Res 2018 05 12;78(9):2248-2261. Epub 2018 Feb 12.

Department of Molecular and Cellular Oncology, The University of Texas MD Anderson Cancer Center, Houston, Texas.

J Clin Oncol 2018 05 8;36(13):1339-1342. Epub 2018 Mar 8.

Johann S. Bergholz, Thomas M. Roberts, and Jean J. Zhao, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA.

Oncotarget 2018 May 1;9(35):23878-23889. Epub 2018 Feb 1.

Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, SC 29425, USA.

Clin Cancer Res 2018 04 6;24(8):1795-1804. Epub 2018 Feb 6.

Department of Cancer Biology, Dana Farber Cancer Institute, Boston, Massachusetts.

PLoS One 2018 18;13(1):e0191433. Epub 2018 Jan 18.

Department of Obstetrics, Gynecology and Reproductive Biology, Michigan State University, Grand Rapids, MI, United States of America.

Elife 2018 03 12;7. Epub 2018 Mar 12.

JCI Insight 2017 12 7;2(23). Epub 2017 Dec 7.

Department of Molecular and Integrative Physiology, University of Michigan, Ann Arbor, Michigan, USA.

Elife 2017 09 19;6. Epub 2017 Sep 19.

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, United States.

Nature 2017 09 20;549(7673):533-537. Epub 2017 Sep 20.

Department of Neurology, Stanford University School of Medicine, Stanford, California, USA.

Biochim Biophys Acta Rev Cancer 2017 Aug 14;1868(1):123-131. Epub 2017 Mar 14.

Department of Cancer Biology, Dana Farber Cancer Institute, 44 Binney St, Boston, MA 02115, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, 44 Binney St, Boston, MA 02115, USA. Electronic address:

Nature 2017 08 16;548(7668):471-475. Epub 2017 Aug 16.

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA.

Proc Natl Acad Sci U S A 2017 07 19;114(27):7095-7100. Epub 2017 Jun 19.

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115;

Cell Rep 2017 07;20(3):549-557

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02215, USA. Electronic address:

Cancer Cell 2017 04;31(4):576-590.e8

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Genetics, Harvard Medical School, Boston, MA 02215, USA. Electronic address:

Neuro Oncol 2017 01 10;19(1):22-30. Epub 2016 Jul 10.

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts (J.N., S.X., V.L., Y.S., P.B., R.B., T.M.R., C.D.S., R.A.S., J.J.Z.); Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts (J.N., S.X., V.L., T.M.R., J.J.Z.); Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts (S.H.R., R.B., K.L.L., W.C.H.); Broad Institute, Boston, Massachusetts (P.B., R.B., W.C.H.); Department of Pathology, Brigham and Women's Hospital, Boston, Massachusetts (S.H.R., K.L.L.); Department of Pathology, Boston Children's Hospital, Boston, Massachusetts (K.L.L.)

Proc Natl Acad Sci U S A 2016 11 31;113(46):13156-13161. Epub 2016 Oct 31.

Department of Ophthalmology, Columbia University, New York, NY 10032;

Elife 2016 10 4;5. Epub 2016 Oct 4.

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, United States.

ACS Med Chem Lett 2016 Oct 2;7(10):908-912. Epub 2016 Aug 2.

Department of Cancer Biology, Dana-Farber Cancer Institute , Boston, Massachusetts 02215, United States.

Gynecol Oncol 2016 09 15;142(3):548-56. Epub 2016 Jul 15.

Cancer Institute, The Second Hospital of Dalian Medical University, Institute of Cancer Stem Cell, Dalian Medical University, Dalian 116044, China. Electronic address:

Cell Discov 2016 20;2:16030. Epub 2016 Sep 20.

Department of Cancer Biology, Dana Farber Cancer Institute, Boston, MA, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA.

Oncotarget 2016 08;7(31):48854-48856

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA.

Proc Natl Acad Sci U S A 2016 08 15;113(35):9810-5. Epub 2016 Aug 15.

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115;

Nat Med 2016 07 6;22(7):723-6. Epub 2016 Jun 6.

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.

Cell Rep 2016 06 9;15(12):2692-704. Epub 2016 Jun 9.

Department of Medical Oncology, Dana Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02115, USA; Department of Medicine, Harvard Medical School, 450 Brookline Avenue, Boston, MA 02115, USA. Electronic address:

Nature 2016 05 27;533(7602):278. Epub 2016 Jan 27.

Oncotarget 2016 Mar;7(11):13153-66

Cancer Institute, The Second Hospital of Dalian Medical University, Institute of Cancer Stem Cell, Dalian Medical University, Dalian 116044, China.

Cancer Cell 2016 Mar;29(3):255-269

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02215, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA; The Broad Institute of MIT and Harvard, Cambridge, MA 02142, USA. Electronic address:

Elife 2015 Dec 3;4. Epub 2015 Dec 3.

Center for Integrative Brain Research, Seattle Children's Research Institute, Seattle, United States.

Nat Commun 2015 Oct 7;6:8501. Epub 2015 Oct 7.

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA.

Trends Biotechnol 2015 Sep 24;33(9):504-13. Epub 2015 Jul 24.

Department of Biomedical Engineering, University of Connecticut, 260 Glenbrook Road, Storrs, CT 06269, USA; Department of Mechanical Engineering, University of Connecticut, 191 Auditorium Road, Storrs, CT 06269, USA. Electronic address:

Cell 2015 Sep;163(1):174-86

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115, USA; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA. Electronic address:

Arterioscler Thromb Vasc Biol 2015 Jun 23;35(6):1434-44. Epub 2015 Apr 23.

From the Klinik III für Innere Medizin, Universität zu Köln, Germany (M.V., J.J., E.M.B., L.M., X.C., T.K., M.Z., M.G., H.t.F., S.B., S.R.); Center for Molecular Medicine Cologne (CMMC), Universität zu Köln, Germany (M.V., J.J., E.M.B., L.M., X.C., T.K., M.Z., M.G., H.t.F., S.B., S.R.); Center for R&D, Uppsala University/County Council of Gävleborg, Gävle, Sweden (O.L.); Klinik für Herz- und Thoraxchirurgie, Universität zu Köln, Germany (M.S.); Cologne Cardiovascular Research Center (CCRC), Universität zu Köln, Germany (H.t.F., S.B., S.R.); Klinik für Kardiologie, Charité Universitätsmedizin, Berlin, Germany (F.B.); Institut für Experimentelle Medizin, Universität zu Köln, Germany (A.S.-K.); and Department of Cancer Biology, Dana Farber Cancer Institute, Boston, MA (J.J.Z.).

J Am Chem Soc 2015 May 7;137(19):6112-5. Epub 2015 May 7.

†Department of Chemistry and Chemical Biology, Northeastern University, Boston, Massachusetts 02115, United States.

Mol Cell Biol 2015 Apr 20;35(7):1182-96. Epub 2015 Jan 20.

Department of Cancer Biology, Dana-Farber Cancer Institute, and Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts, USA.

Biochim Biophys Acta 2015 Apr 2;1855(2):254-63. Epub 2015 Apr 2.

Cancer Institute, Second Affiliated Hospital, Dalian Medical University, Dalian, Liaoning, China; Institute of Cancer Stem Cell, Dalian Medical University, Dalian, Liaoning, China; Department of Cancer Biology, Dana-Farber Cancer Institute Harvard Medical School, Boston, MA, USA. Electronic address:

Nat Rev Cancer 2015 Jan;15(1):7-24

1] Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA. [2] Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, Massachusetts 02115, USA.

Nat Cell Biol 2014 Nov 26;16(11):1080-91. Epub 2014 Oct 26.

1] Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA [2] Department of Genetics, Harvard Medical School, Boston, Massachusetts 02115, USA.

Elife 2014 May 20;3:e01763. Epub 2014 May 20.

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, United States Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, United States

J Clin Invest 2014 Apr 24;124(4):1794-809. Epub 2014 Feb 24.

Proc Natl Acad Sci U S A 2014 Apr 15;111(17):6395-400. Epub 2014 Apr 15.

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115.

Cancer Res 2014 Jan 9;74(1):15-23. Epub 2013 Dec 9.

Authors' Affiliations: Department of Cancer Biology; Division of Women's Cancers, Department of Medical Oncology, Dana-Farber Cancer Institute; Departments of Biological Chemistry and Molecular Pharmacology and Systems Biology; Rodent Histopathology Core, DF/HCC, Harvard Medical School; Department of Surgery, Brigham and Women's Hospital; Division of Signal Transduction, Beth Israel Deaconess Medical Center, Boston; Novartis Institutes for Biomedical Research, Cambridge, Massacheusetts; Department of System Biology, The University of Texas MD Anderson Cancer Center, Houston, Texas; and Novartis Institutes for Biomedical Research, Oncology Disease Area, Novartis Pharma AG, Basel, Switzerland.

Cell Cycle 2013 Dec 15;12(23):3589-93. Epub 2013 Oct 15.

Department of Cancer Biology; Dana-Farber Cancer Institute; Boston, MA USA; Department of Biological Chemistry and Molecular Pharmacology; Harvard Medical School; Boston, MA USA.

Proc Natl Acad Sci U S A 2013 Aug 12;110(35):14372-7. Epub 2013 Aug 12.

Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University, Nashville, TN 37232, USA.

Cancer Res 2013 Jul 30;73(13):4075-85. Epub 2013 Apr 30.

Departments of Medicine, Vanderbilt University, Nashville, Tennessee, USA.

Cell Metab 2013 Jul;18(1):86-98

USDA/ARS Children's Nutrition Research Center, Department of Pediatrics, Baylor College of Medicine, Houston, TX 77030, USA.

Genes Dev 2013 Jul;27(14):1568-80

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA.

Cancer Discov 2013 Jan 20;3(1):44-51. Epub 2012 Dec 20.

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.

Genes Dev 2012 Jul;26(14):1573-86

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts 02215, USA.

Cancer Res 2011 Dec 28;71(24):7481-9. Epub 2011 Oct 28.

Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02215, USA.

J Neurosci 2011 Sep;31(37):13147-56

Division of Hypothalamic Research, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

Nat Med 2011 Aug 7;17(9):1116-20. Epub 2011 Aug 7.

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.

Nature 2010 Dec 24;468(7326):968-72. Epub 2010 Nov 24.

Broad Institute of Harvard and Massachusetts Institute of Technology, 7 Cambridge Center, Cambridge, Massachusetts 02142, USA.

PLoS One 2010 Dec 30;5(12):e15581. Epub 2010 Dec 30.

Functional Genomics and Computational Biology Group, Department of Biostatistics and Computational Biology, Dana-Farber Cancer Institute, Boston, Massachusetts, United States America.

Cell Metab 2010 Jul;12(1):88-95

Division of Hypothalamic Research, Departments of Internal Medicine and Pharmacology, The University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

Cell Metab 2010 Mar;11(3):220-30

Joslin Diabetes Center, Harvard Medical School, Boston, MA 02215, USA.

Endocrinology 2009 Nov 9;150(11):4874-82. Epub 2009 Oct 9.

Division of Hypothalamic Research, Department of Internal Medicine, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390-9077, USA.

Clin Cancer Res 2009 Oct 13;15(20):6309-10. Epub 2009 Oct 13.

Department of Cancer Biology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA.

Cancer Res 2009 Aug 14;69(15):6299-306. Epub 2009 Jul 14.

Department of Medicine and Pathology, Herbert Irving Comprehensive Cancer Center, Institute for Cancer Genetics, College of Physicians and Surgeons, Columbia University, New York, New York 10032, USA.

Nat Rev Drug Discov 2009 Aug;8(8):627-44

Department of Cancer Biology, Dana-Farber Cancer Institute, Pathology, Harvard Medical School, Boston, MA 02115, USA.

Sci Signal 2009 Jul 21;2(80):ra35. Epub 2009 Jul 21.

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.

Curr Opin Cell Biol 2009 Apr 4;21(2):199-208. Epub 2009 Feb 4.

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.

Nature 2008 Aug 25;454(7205):776-9. Epub 2008 Jun 25.

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, Massachusetts 02115, USA.

J Virol 2007 Jul 18;81(13):7069-76. Epub 2007 Apr 18.

Department of Cancer Biology, Dana-Farber Cancer Institute, 44 Binney Street, Boston, MA 02115, USA.

Cell 2007 Jun;129(6):1065-79

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.

Sci STKE 2006 Dec 12;2006(365):pe52. Epub 2006 Dec 12.

Department of Cancer Biology, Dana-Farber Cancer Institute, 44 Binney Street, Harvard Medical School, Boston, MA 02115, USA.

Proc Natl Acad Sci U S A 2006 Oct 23;103(44):16296-300. Epub 2006 Oct 23.

Department of Cancer Biology, Dana-Farber Cancer Institute, Harvard Medical School, 44 Binney Street, Boston, MA 02115, USA.

Proc Natl Acad Sci U S A 2005 Dec 8;102(51):18443-8. Epub 2005 Dec 8.

Department of Cancer Biology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA 02115, USA.

Cell 2005 Jun;121(6):837-48

Howard Hughes Medical Institute, Department of Genetics, Harvard Partners Center for Genetics and Genomics, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, Massachusetts 02115, USA.

Cancer Res 2004 Dec;64(24):8867-75

Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts, USA.

Trends Mol Med 2004 Jul;10(7):344-50

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.

Cancer Cell 2003 Dec;4(6):463-76

Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA.

Cancer Cell 2003 May;3(5):483-95

Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA 02115, USA.