Jean C Y Wang

Jean C Y Wang

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Jean C Y Wang

Jean C Y Wang

Publications by authors named "Jean C Y Wang"

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32Publications

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SIRPαFc treatment targets human acute myeloid leukemia stem cells.

Haematologica 2020 Feb 13. Epub 2020 Feb 13.

Princess Margaret Cancer Centre, University Health Network, University of Toronto, Canada;

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http://dx.doi.org/10.3324/haematol.2019.245167DOI Listing
February 2020

Age-related clonal hematopoiesis: implications for hematopoietic stem cell transplantation.

Curr Opin Hematol 2018 11;25(6):441-445

Princess Margaret Cancer Centre, University Health Network (UHN).

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http://dx.doi.org/10.1097/MOH.0000000000000465DOI Listing
November 2018

Prediction of acute myeloid leukaemia risk in healthy individuals.

Nature 2018 07 9;559(7714):400-404. Epub 2018 Jul 9.

Princess Margaret Cancer Centre, University Health Network (UHN), Toronto, Ontario, Canada.

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http://dx.doi.org/10.1038/s41586-018-0317-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6485381PMC
July 2018

CD47-SIRPα Interactions Regulate Macrophage Uptake of Plasmodium falciparum-Infected Erythrocytes and Clearance of Malaria In Vivo.

Infect Immun 2016 07 23;84(7):2002-2011. Epub 2016 Jun 23.

SAR Laboratories, Sandra Rotman Centre for Global Health, Toronto General Hospital-University Health Network, University of Toronto, Toronto, Ontario, Canada

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http://dx.doi.org/10.1128/IAI.01426-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4936360PMC
July 2016

An Integrated Analysis of Heterogeneous Drug Responses in Acute Myeloid Leukemia That Enables the Discovery of Predictive Biomarkers.

Cancer Res 2016 Mar 1;76(5):1214-24. Epub 2016 Feb 1.

Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada. Department of Medicine, University of Toronto, Toronto, Ontario, Canada. Division of Medical Oncology and Hematology, University Health Network, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1158/0008-5472.CAN-15-2743DOI Listing
March 2016

Bringing Leukemia Stem Cells into the Clinic.

Authors:
Jean C Y Wang

Oncology 2015 10;89 Suppl 1:25-7. Epub 2015 Nov 10.

Princess Margaret Cancer Research Centre, University Health Network, Toronto, Ont., Canada.

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http://dx.doi.org/10.1159/000431061DOI Listing
February 2016

Cancer patient perceptions on the ethical and legal issues related to biobanking.

BMC Med Genomics 2013 Mar 8;6. Epub 2013 Mar 8.

Alden March Bioethics Institute, Albany Medical College, 47 New Scotland Avenue, MC 153, Albany, NY 12208-3478, USA.

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http://dx.doi.org/10.1186/1755-8794-6-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3599691PMC
March 2013

Targeting SIRPα in cancer.

Oncoimmunology 2013 Feb;2(2):e23081

The Campbell Family Cancer Research Institute; Ontario Cancer Institute; Princess Margaret Hospital; Toronto, ON Canada.

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http://www.tandfonline.com/doi/abs/10.4161/onci.23081
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http://dx.doi.org/10.4161/onci.23081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601179PMC
February 2013

Disruption of SIRPα signaling in macrophages eliminates human acute myeloid leukemia stem cells in xenografts.

J Exp Med 2012 Sep 3;209(10):1883-99. Epub 2012 Sep 3.

The Campbell Family Cancer Research Institute, Ontario Cancer Institute, Princess Margaret Hospital, University Health Network, Toronto, Ontario M5G 2M9, Canada.

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http://dx.doi.org/10.1084/jem.20120502DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3457732PMC
September 2012

Evolution of human BCR-ABL1 lymphoblastic leukaemia-initiating cells.

Nature 2011 Jan;469(7330):362-7

Division of Stem Cell and Developmental Biology, Campbell Family Institute for Cancer Research/Ontario Cancer Institute, Toronto, Ontario M5G 1L7, Canada.

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http://dx.doi.org/10.1038/nature09733DOI Listing
January 2011

Good cells gone bad: the cellular origins of cancer.

Authors:
Jean C Y Wang

Trends Mol Med 2010 Mar 10;16(3):145-51. Epub 2010 Feb 10.

Division of Stem Cell and Developmental Biology, Ontario Cancer Institute, Canada.

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http://dx.doi.org/10.1016/j.molmed.2010.01.001DOI Listing
March 2010

Polymorphism in Sirpa modulates engraftment of human hematopoietic stem cells.

Nat Immunol 2007 Dec 4;8(12):1313-23. Epub 2007 Nov 4.

Division of Cellular and Molecular Biology, University Health Network, Toronto, Ontario M5G2M9, Canada.

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http://search.proquest.com/openview/7a8e08fc3fa34e0cd33ae560
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http://dx.doi.org/10.1038/ni1527DOI Listing
December 2007

Comment on "Tumor growth need not be driven by rare cancer stem cells".

Science 2007 Dec;318(5857):1722; author reply 1722

Division of Cell and Molecular Biology, University Health Network, Toronto, Canada.

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http://dx.doi.org/10.1126/science.1149590DOI Listing
December 2007

Evaluating therapeutic efficacy against cancer stem cells: new challenges posed by a new paradigm.

Authors:
Jean C Y Wang

Cell Stem Cell 2007 Nov;1(5):497-501

Division of Cell and Molecular Biology, Toronto General Research Institute, Toronto, ON M5G 1L7, Canada.

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http://dx.doi.org/10.1016/j.stem.2007.10.005DOI Listing
November 2007

Myelodysplastic syndromes: the complexity of stem-cell diseases.

Nat Rev Cancer 2007 Feb;7(2):118-29

Department of Leukemia, University of Texas M. D. Anderson Cancer Center, 1515 Holcombe Boulevard, Houston, Texas 77030, USA.

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http://dx.doi.org/10.1038/nrc2047DOI Listing
February 2007

Individual stem cells with highly variable proliferation and self-renewal properties comprise the human hematopoietic stem cell compartment.

Nat Immunol 2006 Nov 1;7(11):1225-33. Epub 2006 Oct 1.

Division of Cell and Molecular Biology, University Health Network, University of Toronto, Ontario M5G 1L7, Canada.

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http://dx.doi.org/10.1038/ni1393DOI Listing
November 2006

Cancer stem cells: lessons from leukemia.

Trends Cell Biol 2005 Sep;15(9):494-501

Division of Cell and Molecular Biology, University Health Network, and Department of Molecular and Medical Genetics, University of Toronto, 620 University Ave, Toronto, Ontario, M5G 2C1, Canada.

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http://dx.doi.org/10.1016/j.tcb.2005.07.004DOI Listing
September 2005

Concepts of human leukemic development.

Oncogene 2004 Sep;23(43):7164-77

Division of Cell and Molecular Biology, University Health Network, University of Toronto, 620 University Ave, ON M5G 2C1, Canada.

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http://dx.doi.org/10.1038/sj.onc.1207933DOI Listing
September 2004