Jayaraman Chandrasekhar

Jayaraman Chandrasekhar

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Jayaraman Chandrasekhar

Jayaraman Chandrasekhar

Publications by authors named "Jayaraman Chandrasekhar"

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18Publications

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Interaction of 2,4-Diaminopyrimidine-Containing Drugs Including Fedratinib and Trimethoprim with Thiamine Transporters.

Drug Metab Dispos 2017 01 1;45(1):76-85. Epub 2016 Nov 1.

Drug Metabolism Department, Gilead Sciences, Inc., (primary laboratory of origin) (M.M.G., J.H., J.T., E.-I.L., A.S.R.), Biology Department (J.A.W.), and Structural Chemistry Department (J.C.), Gilead Sciences, Inc., Foster City, California; and Department of Biopharmaceutical Sciences and Therapeutics, University of California, San Francisco, California (X.L.).

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http://dx.doi.org/10.1124/dmd.116.073338DOI Listing
January 2017

2-Arylpyrimidines: novel CRF-1 receptor antagonists.

Bioorg Med Chem Lett 2008 Aug 18;18(16):4486-90. Epub 2008 Jul 18.

Neurogen Corporation, 35 Northeast Industrial Road, Branford, CT 06405, USA.

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http://dx.doi.org/10.1016/j.bmcl.2008.07.063DOI Listing
August 2008

Strategies and tactics for optimizing the Hit-to-Lead process and beyond--a computational chemistry perspective.

Drug Discov Today 2008 Feb 11;13(3-4):99-109. Epub 2007 Dec 11.

Neurogen Corporation, 35 N.E. Industrial Road, Branford, CT 06405, United States.

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http://dx.doi.org/10.1016/j.drudis.2007.10.019DOI Listing
February 2008

Heparin resistance.

Lab Hematol 2003 ;9(3):125-31

Department of Medicine, Unity Health System, Rochester, New York, USA.

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May 2004

Contributions of conformational compression and preferential transition state stabilization to the rate enhancement by chorismate mutase.

J Am Chem Soc 2003 Jun;125(23):6892-9

Department of Chemistry, Yale University, 225 Prospect Street, New Haven, Connecticut 06520-8107, USA.

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http://dx.doi.org/10.1021/ja021424rDOI Listing
June 2003

PDDG/PM3 and PDDG/MNDO: improved semiempirical methods.

J Comput Chem 2002 Dec;23(16):1601-22

Department of Chemistry, Yale University, 225 Prospect St., New Haven, Connecticut 06520-8107, USA.

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http://dx.doi.org/10.1002/jcc.10162DOI Listing
December 2002

Improved semiempirical heats of formation through the use of bond and group equivalents.

J Comput Chem 2002 Mar;23(4):498-510

Department of Chemistry, Yale University, 225 Prospect St., New Haven, Connecticut 06520-8107, USA.

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http://dx.doi.org/10.1002/jcc.10023DOI Listing
March 2002