Jayanthi Lea

Jayanthi Lea

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Jayanthi Lea

Jayanthi Lea

Publications by authors named "Jayanthi Lea"

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A Phase II Trial of Stereotactic Ablative Radiation Therapy as a Boost for Locally Advanced Cervical Cancer.

Int J Radiat Oncol Biol Phys 2020 03 5;106(3):464-471. Epub 2019 Nov 5.

Department of Radiation Oncology, University of Texas Southwestern Medical Center, Texas; Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Texas.

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http://dx.doi.org/10.1016/j.ijrobp.2019.10.042DOI Listing
March 2020

Value of Intratumoral Metabolic Heterogeneity and Quantitative F-FDG PET/CT Parameters in Predicting Prognosis for Patients With Cervical Cancer.

AJR Am J Roentgenol 2020 Feb 18:1-9. Epub 2020 Feb 18.

Department of Radiology, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390-8827.

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http://dx.doi.org/10.2214/AJR.19.21604DOI Listing
February 2020

ADP-Ribosylation Levels and Patterns Correlate with Gene Expression and Clinical Outcomes in Ovarian Cancers.

Mol Cancer Ther 2020 Jan 8;19(1):282-291. Epub 2019 Oct 8.

Laboratory of Signaling and Gene Expression, Cecil H. and Ida Green Center for Reproductive Biology Sciences, University of Texas Southwestern Medical Center, Dallas, Texas.

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http://dx.doi.org/10.1158/1535-7163.MCT-19-0569DOI Listing
January 2020

Incorporation of whole pelvic radiation into treatment of stage IVB cervical cancer: A novel treatment strategy.

Gynecol Oncol 2020 01 4;156(1):100-106. Epub 2019 Dec 4.

Section of Gynecologic Oncology, Stephenson Cancer Center, The University of Oklahoma Health Sciences Center, Oklahoma City, OK, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ygyno.2019.10.033DOI Listing
January 2020

Specimen Fragmentation and Loop Electrosurgical Excision Procedure and Cold Knife Cone Biopsy Outcomes.

J Low Genit Tract Dis 2020 Jan;24(1):27-33

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, The University of Texas Southwestern Medical Center, Dallas, TX.

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http://dx.doi.org/10.1097/LGT.0000000000000509DOI Listing
January 2020

Mismatch Repair Protein Expression in Endometrioid Intraepithelial Neoplasia/Atypical Hyperplasia: Should We Screen for Lynch Syndrome in Precancerous Lesions?

Int J Gynecol Pathol 2019 Nov;38(6):533-542

Departments of Pathology (E.L., H.C., K.M., D.H.C., G.R.C., L.L., S.H., J.T., W.Z.) Obstetrics and Gynecology (J.L., D.S.M., W.Z.) Harold C. Simmons Comprehensive Cancer Center (E.L., D.H.C, J.L., D.S.M., W.Z.), UTSW Medical Center, Dallas, Texas.

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http://dx.doi.org/10.1097/PGP.0000000000000557DOI Listing
November 2019

Synergistic STING activation by PC7A nanovaccine and ionizing radiation improves cancer immunotherapy.

J Control Release 2019 Apr 4;300:154-160. Epub 2019 Mar 4.

Department of Pharmacology, Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, 6001 Forest Park Road, Dallas, TX 75390, USA. Electronic address:

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http://dx.doi.org/10.1016/j.jconrel.2019.02.036DOI Listing
April 2019

Tubal Origin of "Ovarian" Low-Grade Serous Carcinoma: A Gene Expression Profile Study.

J Oncol 2019 5;2019:8659754. Epub 2019 Mar 5.

Department of Obstetrics and Gynecology, Henan Provincial People's Hospital, Zhengzhou, China.

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https://www.hindawi.com/journals/jo/2019/8659754/
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http://dx.doi.org/10.1155/2019/8659754DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425354PMC
March 2019

Adjuvant Gemcitabine Plus Docetaxel Followed by Doxorubicin Versus Observation for High-Grade Uterine Leiomyosarcoma: A Phase III NRG Oncology/Gynecologic Oncology Group Study.

J Clin Oncol 2018 Oct 5:JCO1800454. Epub 2018 Oct 5.

Martee L. Hensley, Memorial Sloan Kettering Cancer Center; Martee L. Hensley and Oliver Zivanovic, Weill Cornell Medical College, New York City; Danielle Enserro and Shashikant B. Lele, Roswell Park Comprehensive Cancer Center, Buffalo, NY; Helen Hatcher, Cambridge University Hospitals National Health Service Foundation Trust, Cambridge; Cyril Fisher, University of Birmingham, Birmingham, United Kingdom; Petronella B. Ottevanger, Radboud University Medical Center, Nijmegen, the Netherlands; Anders Krarup-Hansen, University Hospital Copenhagen, Copenhagen, Denmark; Jean-Yves Blay, Centre Leon Berard, Lyon, France; Katherine M. Moxley, University of Oklahoma Health Sciences Center, Oklahoma City, OK; Jayanthi S. Lea, and David S. Miller, The University of Texas Southwestern Medical Center, Dallas, TX; Krishnansu S. Tewari, University of California at Irvine, Orange, CA; Premal H. Thaker, Washington University School of Medicine, and Siteman Cancer Center, St Louis, MO; David M. O'Malley, The Ohio State University College of Medicine, Columbus, OH; Katina Robison, Women and Infants Hospital in Rhode Island, Providence, RI.

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http://ascopubs.org/doi/10.1200/JCO.18.00454
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http://dx.doi.org/10.1200/JCO.18.00454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6241678PMC
October 2018

Third-line Salvage Chemotherapy for Recurrent Carcinoma of the Cervix is Associated With Minimal Response Rate and High Toxicity.

Am J Clin Oncol 2018 08;41(8):797-801

Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of Texas Southwestern Medical Center, Dallas, TX.

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http://dx.doi.org/10.1097/COC.0000000000000372DOI Listing
August 2018

Locally Advanced Cervical Cancer: Outcomes With Variable Adherence to Treatment.

Am J Clin Oncol 2018 05;41(5):447-451

Departments of Obstetrics and Gynecology, Division of Gynecologic Oncology.

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http://dx.doi.org/10.1097/COC.0000000000000300DOI Listing
May 2018

Pre-operative core muscle index in combination with hypoalbuminemia is associated with poor prognosis in advanced ovarian cancer.

J Surg Oncol 2018 Apr 6;117(5):1020-1028. Epub 2018 Feb 6.

The University of Texas Southwestern Medical Center, Dallas, Texas.

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http://dx.doi.org/10.1002/jso.24990DOI Listing
April 2018

Dysregulation of fibulin-5 and matrix metalloproteases in epithelial ovarian cancer.

Oncotarget 2018 Mar 14;9(18):14251-14267. Epub 2018 Feb 14.

Department of Obstetrics and Gynecology, Green Center for Reproductive Biology, University of Texas Southwestern Medical Center, Dallas, Texas, USA.

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http://dx.doi.org/10.18632/oncotarget.24484DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5865667PMC
March 2018

Remote location interstitial brachytherapy with patient stabilization and subsequent transport to an outpatient center for treatment is safe and effective for the treatment of gynecologic malignancies.

Brachytherapy 2016 May-Jun;15(3):341-346. Epub 2016 Mar 19.

Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX; Simmons Comprehensive Cancer Center at the University of Texas Southwestern Medical Center, Dallas, TX. Electronic address:

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http://dx.doi.org/10.1016/j.brachy.2016.02.005DOI Listing
July 2017

A STING-activating nanovaccine for cancer immunotherapy.

Nat Nanotechnol 2017 07 24;12(7):648-654. Epub 2017 Apr 24.

Department of Pharmacology, Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, Texas 75390, USA.

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http://dx.doi.org/10.1038/nnano.2017.52DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500418PMC
July 2017

Response to "Towards implementation of sexual healthcare".

Gynecol Oncol Rep 2017 May 23;20:139. Epub 2017 Apr 23.

The University of Texas Southwestern Medical Center Dallas, Texas, 5323 Harry Hines Blvd., Dallas, TX 75390-9032, United States.

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http://dx.doi.org/10.1016/j.gore.2017.04.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993518PMC
May 2017

The opinions and practices of providers toward the sexual issues of cervical cancer patients undergoing treatment.

Gynecol Oncol 2017 03 9;144(3):586-591. Epub 2017 Jan 9.

The University of Texas Southwestern Medical Center Dallas, Texas, Department of Gynecologic Oncology, 5323 Harry Hines Blvd., Dallas, TX 75390-9032, United States.

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https://linkinghub.elsevier.com/retrieve/pii/S00908258163168
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http://dx.doi.org/10.1016/j.ygyno.2016.12.022DOI Listing
March 2017

Detection of phosphatidylserine-positive exosomes as a diagnostic marker for ovarian malignancies: a proof of concept study.

Oncotarget 2017 Feb;8(9):14395-14407

Harold Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX, USA.

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http://dx.doi.org/10.18632/oncotarget.14795DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5362413PMC
February 2017

Factors influencing primary treatment of midline vulvar cancers.

Gynecol Oncol 2016 07 12;142(1):133-138. Epub 2016 May 12.

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1016/j.ygyno.2016.04.540DOI Listing
July 2016

Para-aortic nodal metastases in cervical cancer: a blind spot in the International Federation of Gynecology and Obstetrics staging system: current diagnosis and management.

Future Oncol 2015 ;11(2):309-22

Department of Radiation Oncology, UT Southwestern Medical Center, Dallas, TX 75390 9183, USA.

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http://dx.doi.org/10.2217/fon.14.200DOI Listing
September 2015

Ovarian involvement in endometrioid adenocarcinoma of uterus.

Gynecol Oncol 2015 Sep 14;138(3):532-5. Epub 2015 Jul 14.

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, TX, United States.

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https://linkinghub.elsevier.com/retrieve/pii/S00908258153007
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http://dx.doi.org/10.1016/j.ygyno.2015.07.012DOI Listing
September 2015

A phase I-II evaluation of veliparib (NSC #737664), topotecan, and filgrastim or pegfilgrastim in the treatment of persistent or recurrent carcinoma of the uterine cervix: an NRG Oncology/Gynecologic Oncology Group study.

Int J Gynecol Cancer 2015 Mar;25(3):484-92

*Summa Cancer Institute, Summa Health System, Akron, OH; †NRG Oncology/Gynecologic Oncology Group Statistics and Data Management Center, Roswell Park Cancer Institute, Buffalo, NY; ‡Case Western Reserve University, Cleveland, OH; §UT Southwestern Medical Center, Dallas, TX; ∥University Hospitals Case Medical Center, Cleveland, OH; ¶University of Washington, Seattle, WA; #University of Iowa, Iowa City, IA; **Decatur Memorial Hospital, Cancer Care Specialists of Central Illinois, Decatur, IL; ††Virginia Commonwealth University, Richmond, VA; and ‡‡Oklahoma University Health Science Center, Oklahoma City, OK.

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http://dx.doi.org/10.1097/IGC.0000000000000380DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4336206PMC
March 2015

Factors associated with clinical trial screening failures in gynecologic oncology.

Gynecol Oncol 2014 Sep 30;134(3):450-4. Epub 2014 Jun 30.

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00908258140106
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http://dx.doi.org/10.1016/j.ygyno.2014.06.023DOI Listing
September 2014

Adnexal masses requiring surgical intervention in women with advanced cervical cancer.

Gynecol Oncol 2014 Sep 9;134(3):552-5. Epub 2014 Jul 9.

University of Texas Southwestern Medical Center, Dallas, TX, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S00908258140107
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http://dx.doi.org/10.1016/j.ygyno.2014.06.032DOI Listing
September 2014

Malignant ovarian germ cell tumor - role of surgical staging and gonadal dysgenesis.

Gynecol Oncol 2014 Jul 14;134(1):84-9. Epub 2014 May 14.

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, TX, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00908258140095
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http://dx.doi.org/10.1016/j.ygyno.2014.05.003DOI Listing
July 2014

Oxygenation in cervical cancer and normal uterine cervix assessed using blood oxygenation level-dependent (BOLD) MRI at 3T.

NMR Biomed 2012 Dec 23;25(12):1321-30. Epub 2012 May 23.

Department of Radiology, University of Texas Southwestern Medical Center, Dallas, TX, USA.

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http://dx.doi.org/10.1002/nbm.2804DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3445718PMC
December 2012

Lymph node metastasis in endometrioid adenocarcinomas of the uterine corpus with occult cervical involvement.

Gynecol Oncol 2012 Oct 16;127(1):43-6. Epub 2012 Jun 16.

Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, UT Southwestern Medical Center, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1016/j.ygyno.2012.06.018DOI Listing
October 2012

Cervical cancer.

Obstet Gynecol Clin North Am 2012 Jun 24;39(2):233-53. Epub 2012 Apr 24.

University of Texas Southwestern School of Medicine, Dallas, TX 75390-9032, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S088985451200025
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http://dx.doi.org/10.1016/j.ogc.2012.02.008DOI Listing
June 2012

Recurrent phyllodes tumor of the vulva: a case report with review of diagnostic criteria and differential diagnosis.

Int J Gynecol Pathol 2010 May;29(3):294-7

Department of Obstetrics and Gynecology, UT Southwestern Medical Center at Dallas, Texas, U SA.

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http://dx.doi.org/10.1097/PGP.0b013e3181c14a8cDOI Listing
May 2010

Secondary cytoreductive surgery for recurrent platinum-sensitive ovarian cancer.

Int J Gynaecol Obstet 2010 Feb 4;108(2):123-7. Epub 2009 Nov 4.

Division of Gynecologic Oncology, Massachusetts General Hospital, Boston, Massachusetts, USA.

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http://doi.wiley.com/10.1016/j.ijgo.2009.08.034
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http://dx.doi.org/10.1016/j.ijgo.2009.08.034DOI Listing
February 2010

Secreted protein acidic and rich in cysteine as a regulator of murine ovarian cancer growth and chemosensitivity.

Am J Obstet Gynecol 2009 Feb 6;200(2):180.e1-7. Epub 2008 Nov 6.

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390-8593, USA.

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http://dx.doi.org/10.1016/j.ajog.2008.08.047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3709016PMC
February 2009

Implications of EGFR inhibition in ovarian cancer cell proliferation.

Gynecol Oncol 2008 Jun;109(3):411-7

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, Texas 75390-9032, USA.

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http://dx.doi.org/10.1016/j.ygyno.2008.02.030DOI Listing
June 2008

Silencing of HPV 18 oncoproteins With RNA interference causes growth inhibition of cervical cancer cells.

Reprod Sci 2007 Jan;14(1):20-8

Division ofGynecologic Oncology, Hamon Center of Therapeutic Oncology Research, University ofTexas Southwestern Medical Center, Dallas, TX75390-9032, USA.

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http://rsx.sagepub.com/content/14/1/20.full.pdf
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http://rsx.sagepub.com/cgi/doi/10.1177/1933719106298189
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http://dx.doi.org/10.1177/1933719106298189DOI Listing
January 2007

Understanding the mechanisms of FHIT inactivation in cervical cancer for biomarker development.

J Soc Gynecol Investig 2004 Jul;11(5):329-37

Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-9032, USA.

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http://dx.doi.org/10.1016/j.jsgi.2003.12.008DOI Listing
July 2004

Adenocarcinoma of the cervix.

Curr Treat Options Oncol 2004 Apr;5(2):119-27

Division of Gynecologic Oncology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, J7.124, Dallas, TX 75390, USA.

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http://dx.doi.org/10.1007/s11864-004-0044-0DOI Listing
April 2004

P16 as a molecular biomarker of cervical adenocarcinoma.

Am J Obstet Gynecol 2004 Mar;190(3):668-73

Laboratory of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, Tex, USA.

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http://dx.doi.org/10.1016/j.ajog.2003.09.038DOI Listing
March 2004

Aberrant p16 methylation is a biomarker for tobacco exposure in cervical squamous cell carcinogenesis.

Am J Obstet Gynecol 2004 Mar;190(3):674-9

Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, and the Hamon Center for Therapeutic Oncology Research, University of Texas Southwestern Medical Center, Dallas, Texas, USA.

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http://dx.doi.org/10.1016/j.ajog.2003.09.036DOI Listing
March 2004

Adenosquamous histology predicts poor outcome in low-risk stage IB1 cervical adenocarcinoma.

Gynecol Oncol 2003 Dec;91(3):558-62

Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, University of Texas Southwestern Medical Center, Dallas, TX 75390-9032, USA.

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http://dx.doi.org/10.1016/j.ygyno.2003.08.020DOI Listing
December 2003

Postconization surveillance of cervical adenocarcinoma in situ. A prospective trial.

J Reprod Med 2003 Oct;48(10):751-5

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, Department of Pathology, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, J7.124, Dallas, TX 75390-9032, USA.

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October 2003

Management of low-risk gestational trophoblastic neoplasia in indigent women.

J Reprod Med 2003 Oct;48(10):780-4

Southwestern Trophoblastic Disease Center, Division of Gynecologic Oncology, Dep. of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas, 75390-9032, USA.

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October 2003

Cervical adenocarcinoma survival among Hispanic and white women: a multicenter cohort study.

Am J Obstet Gynecol 2003 Mar;188(3):640-4

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Texas Southwestern Medical Center, Dallas 75390, USA.

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http://dx.doi.org/10.1067/mob.2003.96DOI Listing
March 2003

Endocervical curettage at conization to predict residual cervical adenocarcinoma in situ.

Gynecol Oncol 2002 Oct;87(1):129-32

Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, UT Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-9032, USA.

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http://dx.doi.org/10.1006/gyno.2002.6791DOI Listing
October 2002

Early-stage cervical adenocarcinoma treated by surgical intent: the role of para-aortic lymph node dissection.

Gynecol Oncol 2002 Feb;84(2):285-8

Division of Gynecologic Oncology, University of Texas Southwestern, Dallas, Texas 75390, USA.

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http://dx.doi.org/10.1006/gyno.2001.6524DOI Listing
February 2002

Stage IIB-IVB cervical adenocarcinoma: prognostic factors and survival.

Gynecol Oncol 2002 Jan;84(1):115-9

University of Texas Southwestern Medical Center, Dallas, Texas 75390-9032, USA.

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http://linkinghub.elsevier.com/retrieve/pii/S009082580196473
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http://dx.doi.org/10.1006/gyno.2001.6473DOI Listing
January 2002