Jayadev Raju

Jayadev Raju

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Jayadev Raju

Publications by authors named "Jayadev Raju"

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Dietary acrylamide exposure in F344 rats and colon tumor-bearing nude mice: Dataset of gene expression of cancer pathway targets and methylation status of tumor suppressor genes in colon mucosae and tumors.

Data Brief 2019 Dec 7;27:104763. Epub 2019 Nov 7.

Regulatory Toxicology Research Division, Bureau of Chemical Safety, Food Directorate, Health Products and Food Branch, Health Canada, Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1016/j.dib.2019.104763DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6889650PMC
December 2019

Fructooligosaccharides and wheat bran fed at similar fermentation levels differentially affect the expression of genes involved in transport, signaling, apoptosis, cell proliferation, and oncogenesis in the colon epithelia of healthy Fischer 344 rats.

Nutr Res 2019 09 1;69:101-113. Epub 2019 Aug 1.

Nutrition Research Division, Food Directorate, Health Products and Food Branch, Health Canada, Ottawa, Ontario, Canada; Sector Strategies Division, Safe Environments Directorate, Healthy Environments and Consumer Safety Branch, Health Canada, Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1016/j.nutres.2019.07.006DOI Listing
September 2019

A reproductive and developmental screening study of the fungal toxin ochratoxin A in Fischer rats.

Mycotoxin Res 2018 Nov 4;34(4):241-255. Epub 2018 Jul 4.

Bureau of Chemical Safety, Food Directorate, Health Products and Food Branch, Health Canada, Ottawa, Ontario, K1A 0K9, Canada.

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http://dx.doi.org/10.1007/s12550-018-0319-0DOI Listing
November 2018

Lack of adverse health effects following 30-weeks of dietary exposure to acrylamide at low doses in male F344 rats.

Toxicol Rep 2016 31;3:673-678. Epub 2016 Aug 31.

Regulatory Toxicology Research Division, Bureau of Chemical Safety, Food Directorate, Health Products and Food Branch Health Canada, Ottawa, Ontario, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S22147500163006
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http://dx.doi.org/10.1016/j.toxrep.2016.08.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5616078PMC
August 2016

Dietary acrylamide exposure in male F344 rats: Dataset of systemic oxidative stress and inflammation markers.

Data Brief 2016 Jun 14;7:460-7. Epub 2016 Feb 14.

Regulatory Toxicology Research Division, Bureau of Chemical Safety, Food Directorate, Health Products and Food Branch, Health Canada, Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1016/j.dib.2016.02.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4789309PMC
June 2016

The impact of low-dose carcinogens and environmental disruptors on tissue invasion and metastasis.

Carcinogenesis 2015 Jun;36 Suppl 1:S128-59

Department of Biochemistry and Cancer Biology, Meharry Medical College, Nashville, TN 37208, USA, Department of Environmental and Occupational Health, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA, Department of Biology/Center for Cancer Research and Therapeutic Development, Clark Atlanta University, Atlanta, GA 30314, USA, Department of Cancer Biology, Vanderbilt University, Nashville, TN 37232, USA, Department of Pathology, Wayne State University, Detroit, MI 48201, USA, Department of Obstetrics and Gynecology, University of Melbourne, Melbourne, Victoria, Australia, Faculty of Pharmacy, Department of Pathology, Kuwait University, Safat 13110, Kuwait, Department of Otolaryngology, University of Michigan Medical College, Ann Arbor, MI 48109, USA, Department of Molecular & Cellular Biochemistry, University of Kentucky, Lexington, KY 40506, USA, Department of Environmental and Radiological Health Sciences/Food Science and Human Nutrition, College of Veterinary Medicine and Biomedical Sciences, Colorado State University/Colorado School of Public Health, Fort Collins, CO 80523-1680, USA, Center for Environmental Carcinogenesis and Risk Assessment, Environmental Protection and Health Prevention Agency, Bologna 40126, Italy, Faculty of Medicine and Health Sciences, University Putra, Serdang, Selangor 43400, Malaysia, Istituto di Genetica Molecolare, CNR, via Abbiategrasso 207, 27100 Pavia, Italy, Toxicology Research Division, Bureau of Chemical Safety Food Directorate, Health Products and Food Branch Health Canada, Ottawa, Ontario K1A0K9, Canada, Lombardi Comprehensive Cancer Center, Georgetown University Medical Center, Washington, DC 20057, USA, Centre for Advanced Research, King George's Medical University, Chowk, Lucknow, Uttar Pradesh 226003, India, Mediterranean Institute of Oncology, Viagrande 95029, Italy, Urology Department, kasr Al-Ainy School of Medicine, Cairo University, El Manial, Cairo 12515, Egypt, Department of Experimental and

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http://carcin.oxfordjournals.org/content/36/Suppl_1/S128.ful
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http://www.carcin.oxfordjournals.org/lookup/doi/10.1093/carc
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http://dx.doi.org/10.1093/carcin/bgv034DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4565611PMC
June 2015

Assessing the carcinogenic potential of low-dose exposures to chemical mixtures in the environment: the challenge ahead.

Authors:
William H Goodson Leroy Lowe David O Carpenter Michael Gilbertson Abdul Manaf Ali Adela Lopez de Cerain Salsamendi Ahmed Lasfar Amancio Carnero Amaya Azqueta Amedeo Amedei Amelia K Charles Andrew R Collins Andrew Ward Anna C Salzberg Annamaria Colacci Ann-Karin Olsen Arthur Berg Barry J Barclay Binhua P Zhou Carmen Blanco-Aparicio Carolyn J Baglole Chenfang Dong Chiara Mondello Chia-Wen Hsu Christian C Naus Clement Yedjou Colleen S Curran Dale W Laird Daniel C Koch Danielle J Carlin Dean W Felsher Debasish Roy Dustin G Brown Edward Ratovitski Elizabeth P Ryan Emanuela Corsini Emilio Rojas Eun-Yi Moon Ezio Laconi Fabio Marongiu Fahd Al-Mulla Ferdinando Chiaradonna Firouz Darroudi Francis L Martin Frederik J Van Schooten Gary S Goldberg Gerard Wagemaker Gladys N Nangami Gloria M Calaf Graeme Williams Gregory T Wolf Gudrun Koppen Gunnar Brunborg H Kim Lyerly Harini Krishnan Hasiah Ab Hamid Hemad Yasaei Hideko Sone Hiroshi Kondoh Hosni K Salem Hsue-Yin Hsu Hyun Ho Park Igor Koturbash Isabelle R Miousse A Ivana Scovassi James E Klaunig Jan Vondráček Jayadev Raju Jesse Roman John Pierce Wise Jonathan R Whitfield Jordan Woodrick Joseph A Christopher Josiah Ochieng Juan Fernando Martinez-Leal Judith Weisz Julia Kravchenko Jun Sun Kalan R Prudhomme Kannan Badri Narayanan Karine A Cohen-Solal Kim Moorwood Laetitia Gonzalez Laura Soucek Le Jian Leandro S D'Abronzo Liang-Tzung Lin Lin Li Linda Gulliver Lisa J McCawley Lorenzo Memeo Louis Vermeulen Luc Leyns Luoping Zhang Mahara Valverde Mahin Khatami Maria Fiammetta Romano Marion Chapellier Marc A Williams Mark Wade Masoud H Manjili Matilde E Lleonart Menghang Xia Michael J Gonzalez Michalis V Karamouzis Micheline Kirsch-Volders Monica Vaccari Nancy B Kuemmerle Neetu Singh Nichola Cruickshanks Nicole Kleinstreuer Nik van Larebeke Nuzhat Ahmed Olugbemiga Ogunkua P K Krishnakumar Pankaj Vadgama Paola A Marignani Paramita M Ghosh Patricia Ostrosky-Wegman Patricia A Thompson Paul Dent Petr Heneberg Philippa Darbre Po Sing Leung Pratima Nangia-Makker Qiang Shawn Cheng R Brooks Robey Rabeah Al-Temaimi Rabindra Roy Rafaela Andrade-Vieira Ranjeet K Sinha Rekha Mehta Renza Vento Riccardo Di Fiore Richard Ponce-Cusi Rita Dornetshuber-Fleiss Rita Nahta Robert C Castellino Roberta Palorini Roslida Abd Hamid Sabine A S Langie Sakina E Eltom Samira A Brooks Sandra Ryeom Sandra S Wise Sarah N Bay Shelley A Harris Silvana Papagerakis Simona Romano Sofia Pavanello Staffan Eriksson Stefano Forte Stephanie C Casey Sudjit Luanpitpong Tae-Jin Lee Takemi Otsuki Tao Chen Thierry Massfelder Thomas Sanderson Tiziana Guarnieri Tove Hultman Valérian Dormoy Valerie Odero-Marah Venkata Sabbisetti Veronique Maguer-Satta W Kimryn Rathmell Wilhelm Engström William K Decker William H Bisson Yon Rojanasakul Yunus Luqmani Zhenbang Chen Zhiwei Hu

Carcinogenesis 2015 Jun;36 Suppl 1:S254-96

Department of Surgery, The Ohio State University College of Medicine, The James Comprehensive Cancer Center, Columbus, OH 43210, USA.

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http://carcin.oxfordjournals.org/content/36/Suppl_1/S254.ful
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http://carcin.oxfordjournals.org/content/36/Suppl_1/S254.ful
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http://www.ilcambiamento.it/files/carcinogenesi.pdf
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http://www.carcin.oxfordjournals.org/lookup/doi/10.1093/carc
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http://dx.doi.org/10.1093/carcin/bgv039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480130PMC
June 2015

Disruptive environmental chemicals and cellular mechanisms that confer resistance to cell death.

Carcinogenesis 2015 Jun;36 Suppl 1:S89-110

Department of Chemistry and Biochemistry, Yeungnam University, Gyeongsan 712-749, South Korea, Sultan Zainal Abidin University, Malaysia, Plant Biotechnologies Inc, St. Albert AB, Canada, Computer Science Department, Southern Illinois University, Carbondale, IL 62901, USA, Department of Urology, University of California Davis, Sacramento, CA 95817, USA, Department of Pharmacology and Toxicology, University of Vienna, Austria, University of Puerto Rico, Medical Sciences Campus, School of Public Health, Nutrition Program, San Juan Puerto Rico 00936-5067, USA, Department of Anatomy, College of Medicine, Yeungnam University, Daegu, 705-717, South Korea, School of Biomedical Science, The Chinese University Of Hong Kong, Hong Kong, China, Siriraj Center of Excellence for Stem Cell Research, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok 10700, Thailand, Department of Otolaryngology/Head and Neck Surgery, Head and Neck Cancer Research Division, Johns Hopkins University School of Medicine, Baltimore, MD 21231, USA, Department of Pharmaceutical Sciences, Mary Babb Randolph Cancer Center, West Virginia University, Morgantown, WV 26506, USA, Department of Molecular Medicine and Medical Biotechnology, Federico II University of Naples, 80131 Naples, Italy, Department of Molecular and Experimental Medicine, MEM 180, The Scripps Research Institute, La Jolla, CA 92037, USA, Department of Biology, Jackson State University, Jackson, MS 39217, USA, Department of Pathology, Kuwait University, Safat 13110, Kuwait, Department of Experimental and Clinical Medicine, University of Firenze, Firenze, 50134, Italy, Department of Environmental and Radiological Health Sciences, Colorado state University/ Colorado School of Public Health, Fort Collins, CO 80523-1680, USA, Center for Environmental Carcinogenesis and Risk Assessment, Environmental Protection and Health Prevention Agency, Bologna, 40126, Italy, Faculty of Medicine and Health Sciences, Universiti Putra Malaysia, Se

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http://dx.doi.org/10.1093/carcin/bgv032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4565614PMC
June 2015

Fermentable Carbohydrates Differentially Affect Colon Tumor Formation in Azoxymethane-Induced Male Fischer 344 Rats.

J Nutr 2015 Apr;146(4):737-744

Nutrition Research Division, Healthy Environments and Consumer Safety Branch, Health Canada, Ottawa, Ontario, Canada.

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https://academic.oup.com/jn/article/146/4/737/4584906
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http://dx.doi.org/10.3945/jn.115.214833DOI Listing
April 2015

Toxicological effects of short-term dietary acrylamide exposure in male F344 rats.

Environ Toxicol Pharmacol 2015 Jan 22;39(1):85-92. Epub 2014 Nov 22.

Regulatory Toxicology Research Division, Bureau of Chemical Safety, Food Directorate, Health Products and Food Branch Health Canada, Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1016/j.etap.2014.11.009DOI Listing
January 2015

Negligible colon cancer risk from food-borne acrylamide exposure in male F344 rats and nude (nu/nu) mice-bearing human colon tumor xenografts.

PLoS One 2013 5;8(9):e73916. Epub 2013 Sep 5.

Toxicology Research Division, Bureau of Chemical Safety Food Directorate, Health Products and Food Branch, Health Canada, Ottawa, Ontario, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0073916PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3764052PMC
June 2014

Dietary acrylamide does not increase colon aberrant crypt foci formation in male F344 rats.

Food Chem Toxicol 2011 Jun 21;49(6):1373-80. Epub 2011 Mar 21.

Toxicology Research Division, Bureau of Chemical Safety, Food Directorate, Health Products and Food Branch Health Canada, Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1016/j.fct.2011.03.022DOI Listing
June 2011

Estrogen receptor-β mediates the inhibition of DLD-1 human colon adenocarcinoma cells by soy isoflavones.

Nutr Cancer 2011 ;63(1):139-50

Toxicology Research Division, Bureau of Chemical Safety, Food Directorate, Health Products and Food Branch, Health Canada, Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1080/01635581.2010.516867DOI Listing
May 2011

Dietary fructooligosaccharides and wheat bran elicit specific and dose-dependent gene expression profiles in the proximal colon epithelia of healthy Fischer 344 rats.

J Nutr 2011 May 23;141(5):790-7. Epub 2011 Mar 23.

Nutrition Research Division, Health Products and Food Branch, Health Canada, Banting Research Centre, Ottawa, Canada.

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http://dx.doi.org/10.3945/jn.110.133421DOI Listing
May 2011

Potential of magnetic resonance spectroscopy in assessing the effect of fatty acids on inflammatory bowel disease in an animal model.

Lipids 2010 Sep 19;45(9):843-54. Epub 2010 Aug 19.

National Research Council Institute for Biodiagnostics, 435 Ellice Ave., Winnipeg, MB, R3B 1Y6, Canada.

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http://dx.doi.org/10.1007/s11745-010-3455-7DOI Listing
September 2010

Cancer chemopreventive and therapeutic effects of diosgenin, a food saponin.

Nutr Cancer 2009 ;61(1):27-35

Toxicology Research Division, Bureau of Chemical Safety, Food Directorate, Health Products and Food Branch, Health Canada, Ottawa, Ontario, Canada.

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http://dx.doi.org/10.1080/01635580802357352DOI Listing
April 2009

Azoxymethane-induced rat aberrant crypt foci: relevance in studying chemoprevention of colon cancer.

Authors:
Jayadev Raju

World J Gastroenterol 2008 Nov;14(43):6632-5

Toxicology Research Division, Bureau of Chemical Safety, Food Directorate, Health Products and Food Branch, Health Canada, C218 Banting Building, Postal Locator 2202D, Ottawa, K1A 0L2, Ontario, Canada.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2773303PMC
http://dx.doi.org/10.3748/wjg.14.6632DOI Listing
November 2008

Detection of inflammatory bowel disease by proton magnetic resonance spectroscopy (1H MRS) using an animal model.

J Inflamm (Lond) 2007 Nov 26;4:24. Epub 2007 Nov 26.

National Research Council Institute for Biodiagnostics, Winnipeg, Canada.

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http://dx.doi.org/10.1186/1476-9255-4-24DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2211293PMC
November 2007

Diosgenin, a naturally occurring steroid [corrected] saponin suppresses 3-hydroxy-3-methylglutaryl CoA reductase expression and induces apoptosis in HCT-116 human colon carcinoma cells.

Cancer Lett 2007 Oct 6;255(2):194-204. Epub 2007 Jun 6.

Toxicology Research Division, Food Directorate, Health Products and Food Branch, Health Canada, Ottawa, Ont., Canada.

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http://dx.doi.org/10.1016/j.canlet.2007.04.011DOI Listing
October 2007

Beta-escin inhibits colonic aberrant crypt foci formation in rats and regulates the cell cycle growth by inducing p21(waf1/cip1) in colon cancer cells.

Mol Cancer Ther 2006 Jun;5(6):1459-66

Department of Medicine, OU Cancer Institute, University of Oklahoma Health Sciences Center, 975 Northeast 10th Street, Oklahoma City, OK 73104, USA.

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http://mct.aacrjournals.org/cgi/doi/10.1158/1535-7163.MCT-05
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http://dx.doi.org/10.1158/1535-7163.MCT-05-0495DOI Listing
June 2006

Obese state leads to elevated levels of TGF-beta and COX isoforms in platelets of Zucker rats.

Mol Cell Biochem 2006 Mar 14;284(1-2):19-24. Epub 2006 Feb 14.

Department of Biology, University of Waterloo, Waterloo, Ontario, Canada.

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http://dx.doi.org/10.1007/s11010-005-9008-3DOI Listing
March 2006

Low doses of beta-carotene and lutein inhibit AOM-induced rat colonic ACF formation but high doses augment ACF incidence.

Int J Cancer 2005 Feb;113(5):798-802

Chemoprevention Program, Institute For Cancer Prevention, American Health Foundation Cancer Center, Valhalla, NY, USA.

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http://doi.wiley.com/10.1002/ijc.20640
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http://dx.doi.org/10.1002/ijc.20640DOI Listing
February 2005

Elevated insulin receptor protein expression in experimentally induced colonic tumors.

Cancer Lett 2004 Aug;211(2):145-53

Department of Human Nutritional Sciences, University of Manitoba, Winnipeg, Man., Canada R3T 2N2.

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http://dx.doi.org/10.1016/j.canlet.2004.02.015DOI Listing
August 2004

Diosgenin, a steroid saponin of Trigonella foenum graecum (Fenugreek), inhibits azoxymethane-induced aberrant crypt foci formation in F344 rats and induces apoptosis in HT-29 human colon cancer cells.

Cancer Epidemiol Biomarkers Prev 2004 Aug;13(8):1392-8

Division of Nutritional Carcinogenesis, Institute for Cancer Prevention, American Health Foundation Cancer Center, 1 Dana Road, Valhalla, NY 10595, USA.

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August 2004

Overexpression of caveolin-1 in experimental colon adenocarcinomas and human colon cancer cell lines.

Oncol Rep 2004 May;11(5):957-63

Chemoprevention Program, Institute for Cancer Prevention, American Health Foundation-Cancer Center, Valhalla, NY 10595, USA.

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May 2004

Energy restriction reduces the number of advanced aberrant crypt foci and attenuates the expression of colonic transforming growth factor beta and cyclooxygenase isoforms in Zucker obese (fa/fa) rats.

Cancer Res 2003 Oct;63(20):6595-601

Department of Human Nutritional Sciences, University of Manitoba, Winnipeg, Manitoba, R3T 2N2 Canada.

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October 2003

Steady state levels of transforming growth factor-beta1 and -beta2 mRNA and protein expression are elevated in colonic tumors in vivo irrespective of dietary lipids intervention.

Int J Cancer 2002 Aug;100(6):635-41

Department of Human Nutritional Sciences, University of Manitoba, Winnipeg, R3T 2N2 Manitoba, Canada.

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http://dx.doi.org/10.1002/ijc.10522DOI Listing
August 2002

Differential modulation of transforming growth factor-betas and cyclooxygenases in the platelet lysates of male F344 rats by dietary lipids and piroxicam.

Mol Cell Biochem 2002 Feb;231(1-2):139-46

Department of Foods and Nutrition, University of Manitoba, Winnipeg, Canada.

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http://dx.doi.org/10.1023/a:1014468932482DOI Listing
February 2002