Jay Shendure

Jay Shendure

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Jay Shendure

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MaveDB: an open-source platform to distribute and interpret data from multiplexed assays of variant effect.

Genome Biol 2019 Nov 4;20(1):223. Epub 2019 Nov 4.

Bioinformatics Division, The Walter and Eliza Hall Institute of Medical Research, Parkville, VIC, Australia.

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http://dx.doi.org/10.1186/s13059-019-1845-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827219PMC
November 2019

Supervised classification enables rapid annotation of cell atlases.

Nat Methods 2019 Oct 9;16(10):983-986. Epub 2019 Sep 9.

Department of Genome Sciences, University of Washington, Seattle, WA, USA.

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http://dx.doi.org/10.1038/s41592-019-0535-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6791524PMC
October 2019

Mechanisms of Interplay between Transcription Factors and the 3D Genome.

Mol Cell 2019 Oct 11;76(2):306-319. Epub 2019 Sep 11.

Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA; Howard Hughes Medical Institute, Seattle, WA 98195, USA; Brotman Baty Institute for Precision Medicine, Seattle, WA 98195, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2019.08.010DOI Listing
October 2019

Sci-Hi-C: A single-cell Hi-C method for mapping 3D genome organization in large number of single cells.

Methods 2019 Sep 16. Epub 2019 Sep 16.

Division of Hematology, University of Washington School of Medicine, Seattle, WA, United States; Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.ymeth.2019.09.012DOI Listing
September 2019

Saturation mutagenesis of twenty disease-associated regulatory elements at single base-pair resolution.

Nat Commun 2019 Aug 8;10(1):3583. Epub 2019 Aug 8.

Department of Bioengineering and Therapeutic Sciences, University of California San Francisco, San Francisco, CA, 94158, USA.

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http://dx.doi.org/10.1038/s41467-019-11526-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6687891PMC
August 2019

High-Throughput Single-Cell Sequencing with Linear Amplification.

Mol Cell 2019 Aug 28. Epub 2019 Aug 28.

Department of Genome Sciences, University of Washington, Seattle, WA, USA; Allen Discovery Center for Cell Lineage Tracing, Seattle, WA, USA; Brotman Baty Institute for Precision Medicine, Seattle, WA, USA; Howard Hughes Medical Institute, Seattle, WA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2019.08.002DOI Listing
August 2019

Expanding the single-cell genomics toolkit.

Nat Genet 2019 06;51(6):931-932

Department of Genome Sciences, University of Washington, Seattle, WA, USA.

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http://dx.doi.org/10.1038/s41588-019-0429-4DOI Listing
June 2019

Functional testing of thousands of osteoarthritis-associated variants for regulatory activity.

Nat Commun 2019 06 4;10(1):2434. Epub 2019 Jun 4.

Department of Genome Sciences, University of Washington, Seattle, WA, 98195, USA.

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http://dx.doi.org/10.1038/s41467-019-10439-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547687PMC
June 2019

A combination of transcription factors mediates inducible interchromosomal contacts.

Elife 2019 05 13;8. Epub 2019 May 13.

Department of Genome Sciences, University of Washington, Seattle, United States.

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http://dx.doi.org/10.7554/eLife.42499DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6548505PMC
May 2019

Publisher Correction: DNA sequencing at 40: past, present and future.

Nature 2019 Apr;568(7752):E11

Department of Genome Sciences, University of Washington, Seattle, Washington, USA.

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http://dx.doi.org/10.1038/s41586-019-1120-8DOI Listing
April 2019

Genomic Medicine-Progress, Pitfalls, and Promise.

Cell 2019 Mar;177(1):45-57

Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA.

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http://dx.doi.org/10.1016/j.cell.2019.02.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6531313PMC
March 2019

Condensin-Dependent Chromatin Compaction Represses Transcription Globally during Quiescence.

Mol Cell 2019 02 27;73(3):533-546.e4. Epub 2018 Dec 27.

Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2018.11.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368455PMC
February 2019

High Sensitivity Profiling of Chromatin Structure by MNase-SSP.

Cell Rep 2019 Feb;26(9):2465-2476.e4

Department of Genome Sciences, University of Washington, Seattle, WA, USA; Brotman-Baty Institute for Precision Medicine, Seattle, WA, USA; Howard Hughes Medical Institute, Seattle, WA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.02.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582983PMC
February 2019

CADD: predicting the deleteriousness of variants throughout the human genome.

Nucleic Acids Res 2019 Jan;47(D1):D886-D894

Berlin Institute of Health (BIH), 10178 Berlin, Germany.

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http://dx.doi.org/10.1093/nar/gky1016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323892PMC
January 2019

A Genome-wide Framework for Mapping Gene Regulation via Cellular Genetic Screens.

Cell 2019 01 3;176(1-2):377-390.e19. Epub 2019 Jan 3.

Department of Genome Sciences, University of Washington, Seattle, WA 98105, USA; Brotman Baty Institute for Precision Medicine, University of Washington, Seattle, WA 98105, USA; Howard Hughes Medical Institute, Seattle, WA 98105, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00928674183155
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http://dx.doi.org/10.1016/j.cell.2018.11.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690346PMC
January 2019

A Multiplex Homology-Directed DNA Repair Assay Reveals the Impact of More Than 1,000 BRCA1 Missense Substitution Variants on Protein Function.

Am J Hum Genet 2018 10 12;103(4):498-508. Epub 2018 Sep 12.

Department of Biomedical Informatics, Ohio State University, Columbus, OH 43210, USA; Comprehensive Cancer Center, Ohio State University, Columbus, OH 43210, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00029297183024
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http://dx.doi.org/10.1016/j.ajhg.2018.07.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6174279PMC
October 2018

Prediction of Susceptibility to First-Line Tuberculosis Drugs by DNA Sequencing.

N Engl J Med 2018 10 26;379(15):1403-1415. Epub 2018 Sep 26.

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http://dx.doi.org/10.1056/NEJMoa1800474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6121966PMC
October 2018

Cicero Predicts cis-Regulatory DNA Interactions from Single-Cell Chromatin Accessibility Data.

Mol Cell 2018 09 2;71(5):858-871.e8. Epub 2018 Aug 2.

Department of Genome Sciences, University of Washington, Seattle, WA, USA; Brotman Baty Institute for Precision Medicine, Seattle, WA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2018.06.044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6582963PMC
September 2018

A Single-Cell Atlas of In Vivo Mammalian Chromatin Accessibility.

Cell 2018 08 2;174(5):1309-1324.e18. Epub 2018 Aug 2.

Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA; Brotman Baty Institute for Precision Medicine, Seattle, WA 98195, USA; Howard Hughes Medical Institute, Seattle, WA 98195, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2018.06.052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158300PMC
August 2018

Tagmentation-Based Library Preparation for Low DNA Input Whole Genome Bisulfite Sequencing.

Methods Mol Biol 2018 ;1708:105-122

Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, 69120, Heidelberg, Germany.

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http://link.springer.com/10.1007/978-1-4939-7481-8_6
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http://dx.doi.org/10.1007/978-1-4939-7481-8_6DOI Listing
July 2018

FlashFry: a fast and flexible tool for large-scale CRISPR target design.

BMC Biol 2018 07 5;16(1):74. Epub 2018 Jul 5.

Department of Genome Sciences, University of Washington, Seattle, WA, USA.

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http://dx.doi.org/10.1186/s12915-018-0545-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6033233PMC
July 2018

Functional characterization of enhancer evolution in the primate lineage.

Genome Biol 2018 07 25;19(1):99. Epub 2018 Jul 25.

Department of Genome Sciences, University of Washington, Seattle, WA, 98195, USA.

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http://dx.doi.org/10.1186/s13059-018-1473-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060477PMC
July 2018

Using DNase Hi-C techniques to map global and local three-dimensional genome architecture at high resolution.

Methods 2018 06 31;142:59-73. Epub 2018 Jan 31.

Institute for Stem Cell and Regenerative Medicine, University of Washington, USA; Division of Hematology, Department of Medicine, University of Washington, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ymeth.2018.01.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5993575PMC
June 2018

Simultaneous single-cell profiling of lineages and cell types in the vertebrate brain.

Nat Biotechnol 2018 06 28;36(5):442-450. Epub 2018 Mar 28.

Department of Molecular and Cellular Biology, Harvard University, Cambridge, Massachusetts, USA.

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http://dx.doi.org/10.1038/nbt.4103DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938111PMC
June 2018

Highly scalable generation of DNA methylation profiles in single cells.

Nat Biotechnol 2018 06 9;36(5):428-431. Epub 2018 Apr 9.

Department of Molecular & Medical Genetics, Oregon Health & Science University, Portland, Oregon, USA.

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http://dx.doi.org/10.1038/nbt.4112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5938134PMC
June 2018

Identifying Novel Enhancer Elements with CRISPR-Based Screens.

ACS Chem Biol 2018 02 10;13(2):326-332. Epub 2018 Jan 10.

Department of Genome Sciences, University of Washington , Seattle, Washington 98195, United States.

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http://dx.doi.org/10.1021/acschembio.7b00778DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218247PMC
February 2018

Targeted Capture and High-Throughput Sequencing Using Molecular Inversion Probes (MIPs).

Methods Mol Biol 2017 ;1492:95-106

Department of Genome Sciences, University of Washington School of Medicine, 3720 15th Ave NE, S413C, Box 355065, Seattle, WA, 98195-5065, USA.

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http://dx.doi.org/10.1007/978-1-4939-6442-0_6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5484527PMC
January 2018

Quantitative Missense Variant Effect Prediction Using Large-Scale Mutagenesis Data.

Cell Syst 2018 Jan 6;6(1):116-124.e3. Epub 2017 Dec 6.

Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA; Department of Bioengineering, University of Washington, Seattle, WA 98195, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S24054712173049
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http://dx.doi.org/10.1016/j.cels.2017.11.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5799033PMC
January 2018

Encephalopathy caused by novel mutations in the CMP-sialic acid transporter, SLC35A1.

Am J Med Genet A 2017 Nov 29;173(11):2906-2911. Epub 2017 Aug 29.

Human Genetics Program, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, California.

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http://doi.wiley.com/10.1002/ajmg.a.38412
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http://dx.doi.org/10.1002/ajmg.a.38412DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5650519PMC
November 2017

De Novo Mutations in Protein Kinase Genes CAMK2A and CAMK2B Cause Intellectual Disability.

Authors:
Sébastien Küry Geeske M van Woerden Thomas Besnard Martina Proietti Onori Xénia Latypova Meghan C Towne Megan T Cho Trine E Prescott Melissa A Ploeg Stephan Sanders Holly A F Stessman Aurora Pujol Ben Distel Laurie A Robak Jonathan A Bernstein Anne-Sophie Denommé-Pichon Gaëtan Lesca Elizabeth A Sellars Jonathan Berg Wilfrid Carré Øyvind Løvold Busk Bregje W M van Bon Jeff L Waugh Matthew Deardorff George E Hoganson Katherine B Bosanko Diana S Johnson Tabib Dabir Øystein Lunde Holla Ajoy Sarkar Kristian Tveten Julitta de Bellescize Geir J Braathen Paulien A Terhal Dorothy K Grange Arie van Haeringen Christina Lam Ghayda Mirzaa Jennifer Burton Elizabeth J Bhoj Jessica Douglas Avni B Santani Addie I Nesbitt Katherine L Helbig Marisa V Andrews Amber Begtrup Sha Tang Koen L I van Gassen Jane Juusola Kimberly Foss Gregory M Enns Ute Moog Katrin Hinderhofer Nagarajan Paramasivam Sharyn Lincoln Brandon H Kusako Pierre Lindenbaum Eric Charpentier Catherine B Nowak Elouan Cherot Thomas Simonet Claudia A L Ruivenkamp Sihoun Hahn Catherine A Brownstein Fan Xia Sébastien Schmitt Wallid Deb Dominique Bonneau Mathilde Nizon Delphine Quinquis Jamel Chelly Gabrielle Rudolf Damien Sanlaville Philippe Parent Brigitte Gilbert-Dussardier Annick Toutain Vernon R Sutton Jenny Thies Lisenka E L M Peart-Vissers Pierre Boisseau Marie Vincent Andreas M Grabrucker Christèle Dubourg Wen-Hann Tan Nienke E Verbeek Martin Granzow Gijs W E Santen Jay Shendure Bertrand Isidor Laurent Pasquier Richard Redon Yaping Yang Matthew W State Tjitske Kleefstra Benjamin Cogné Slavé Petrovski Kyle Retterer Evan E Eichler Jill A Rosenfeld Pankaj B Agrawal Stéphane Bézieau Sylvie Odent Ype Elgersma Sandra Mercier

Am J Hum Genet 2017 Nov;101(5):768-788

CHU Nantes, Service de Génétique Médicale, 9 quai Moncousu, 44093 Nantes Cedex 1, France.

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http://dx.doi.org/10.1016/j.ajhg.2017.10.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5673671PMC
November 2017

DNA sequencing at 40: past, present and future.

Nature 2017 10 11;550(7676):345-353. Epub 2017 Oct 11.

Department of Genome Sciences, University of Washington, Seattle, Washington, USA.

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http://dx.doi.org/10.1038/nature24286DOI Listing
October 2017

Variant Interpretation: Functional Assays to the Rescue.

Am J Hum Genet 2017 Sep;101(3):315-325

Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA; Department of Bioengineering, University of Washington, Seattle, WA 98195, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2017.07.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590843PMC
September 2017

The 4D nucleome project.

Nature 2017 09;549(7671):219-226

Department of Bioengineering, University of California San Diego, La Jolla, California 92093, USA.

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http://dx.doi.org/10.1038/nature23884DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5617335PMC
September 2017

CRISPR/Cas9-Mediated Scanning for Regulatory Elements Required for HPRT1 Expression via Thousands of Large, Programmed Genomic Deletions.

Am J Hum Genet 2017 Aug 14;101(2):192-205. Epub 2017 Jul 14.

Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA; Howard Hughes Medical Institute, Seattle, WA 98195, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00029297173024
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http://dx.doi.org/10.1016/j.ajhg.2017.06.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5544381PMC
August 2017

Quantification of differential gene expression by multiplexed targeted resequencing of cDNA.

Nat Commun 2017 05 5;8:15190. Epub 2017 May 5.

Department of Human Genetics, Donders Institute for Brain, Cognition and Behaviour, Radboud University Medical Center, PO Box 9101, 6500 HB, Nijmegen, The Netherlands.

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http://dx.doi.org/10.1038/ncomms15190DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5424154PMC
May 2017

The dynamic three-dimensional organization of the diploid yeast genome.

Elife 2017 05 24;6. Epub 2017 May 24.

Department of Genome Sciences, University of Washington, Seattle, United States.

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http://dx.doi.org/10.7554/eLife.23623DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476426PMC
May 2017

Massively multiplex single-cell Hi-C.

Nat Methods 2017 03 30;14(3):263-266. Epub 2017 Jan 30.

Department of Genome Sciences, University of Washington, Seattle, Washington, USA.

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http://dx.doi.org/10.1038/nmeth.4155DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5330809PMC
March 2017

Mapping 3D genome architecture through in situ DNase Hi-C.

Nat Protoc 2016 11 29;11(11):2104-21. Epub 2016 Sep 29.

Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, Washington, USA.

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http://www.nature.com/articles/nprot.2016.126
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http://dx.doi.org/10.1038/nprot.2016.126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547819PMC
November 2016

Classification and characterization of microsatellite instability across 18 cancer types.

Nat Med 2016 11 3;22(11):1342-1350. Epub 2016 Oct 3.

Department of Laboratory Medicine, University of Washington, Seattle, Washington, USA.

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http://dx.doi.org/10.1038/nm.4191DOI Listing
November 2016

The power of multiplexed functional analysis of genetic variants.

Nat Protoc 2016 10 1;11(10):1782-7. Epub 2016 Sep 1.

Department of Genome Sciences, University of Washington, Seattle, Washington, USA.

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http://dx.doi.org/10.1038/nprot.2016.135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6690347PMC
October 2016

Genome evolution in the allotetraploid frog Xenopus laevis.

Nature 2016 10;538(7625):336-343

University of California, Berkeley, Department of Molecular and Cell Biology and Center for Integrative Genomics, Life Sciences Addition #3200, Berkeley, California 94720-3200, USA.

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http://dx.doi.org/10.1038/nature19840DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5313049PMC
October 2016

Complex Minigene Library Vaccination for Discovery of Pre-Erythrocytic Plasmodium T Cell Antigens.

PLoS One 2016 12;11(4):e0153449. Epub 2016 Apr 12.

Department of Laboratory Medicine, University of Washington, Seattle, Washington, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0153449PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4829254PMC
August 2016

Human genomics: A deep dive into genetic variation.

Authors:
Jay Shendure

Nature 2016 08;536(7616):277-8

Department of Genome Sciences, University of Washington, Seattle, Washington 98195, USA, and is an investigator of the Howard Hughes Medical Institute.

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http://dx.doi.org/10.1038/536277aDOI Listing
August 2016

Whole-organism lineage tracing by combinatorial and cumulative genome editing.

Science 2016 Jul 26;353(6298):aaf7907. Epub 2016 May 26.

Department of Genome Sciences, University of Washington, Seattle, WA, USA. Howard Hughes Medical Institute, Seattle, WA, USA.

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http://dx.doi.org/10.1126/science.aaf7907DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4967023PMC
July 2016

Cilia gene mutations cause atrioventricular septal defects by multiple mechanisms.

Hum Mol Genet 2016 07 23;25(14):3011-3028. Epub 2016 Jun 23.

Departments of Pediatrics, Pathology, and Human Genetics, The University of Chicago, Chicago, IL 60637, USA,

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http://dx.doi.org/10.1093/hmg/ddw155DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5181596PMC
July 2016

Fragment Length of Circulating Tumor DNA.

PLoS Genet 2016 07 18;12(7):e1006162. Epub 2016 Jul 18.

Department of Genome Sciences, University of Washington, Seattle, Washington, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1006162DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948782PMC
July 2016

Massively Parallel Genetics.

Genetics 2016 06;203(2):617-9

Department of Genome Sciences and Department of Medicine , University of Washington, Seattle, Washington 98115

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http://dx.doi.org/10.1534/genetics.115.180562DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4896180PMC
June 2016

Long-read sequence assembly of the gorilla genome.

Science 2016 Apr;352(6281):aae0344

Department of Genome Sciences, University of Washington School of Medicine, Seattle, WA 98195, USA. Howard Hughes Medical Institute, University of Washington, Seattle, WA 98195, USA.

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http://dx.doi.org/10.1126/science.aae0344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4920363PMC
April 2016

LOX Mutations Predispose to Thoracic Aortic Aneurysms and Dissections.

Circ Res 2016 Mar 12;118(6):928-34. Epub 2016 Jan 12.

From the Departments of Internal Medicine (D.G., E.S.R., L.G., X.D., Z.R., B.C., E.M.H., D.M.M.) and Cardiothoracic and Vascular Surgery (A.E., H.J.S.), University of Texas Health Science Center, Houston; Department of Molecular and Human Genetics, Center for Statistical Genetics, Baylor College of Medicine, Houston, TX (R.L.P.S.-C., S.M.L.); Laboratory for Vascular Translational Science, INSERM U1148, Hôpital Bichat, Paris, France (P.A., G.J., C.B.); Centre National de Référence pour le syndrome de Marfan et apparentés, Département de Génétique Moléculaire, AP-HP, Hôpital Bichat, Paris, France (P.A., C.B.); Department of Pediatrics, MetroHealth Medical Center, Cleveland, OH (R.M.); Department of Medicine, Stanford University Medical Center, CA (D.L.); and Department of Genome Sciences, University of Washington, Seattle (M.J.B., J.S., D.A.N.).

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http://dx.doi.org/10.1161/CIRCRESAHA.115.307130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4839295PMC
March 2016

Smash and DASH with Cas9.

Genome Biol 2016 Mar 5;17:42. Epub 2016 Mar 5.

Department of Genome Sciences, University of Washington, 3720 15th Ave NE, Seattle, WA, 98195, USA.

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http://dx.doi.org/10.1186/s13059-016-0905-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4779193PMC
March 2016

Understanding Spatial Genome Organization: Methods and Insights.

Genomics Proteomics Bioinformatics 2016 Feb 11;14(1):7-20. Epub 2016 Feb 11.

Institute for Stem Cell and Regenerative Medicine, University of Washington, Seattle, WA 98109, USA; Division of Hematology, University of Washington, Seattle, WA 98195, USA; Department of Medicine, University of Washington, Seattle, WA 98195, USA. Electronic address:

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http://dx.doi.org/10.1016/j.gpb.2016.01.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4792841PMC
February 2016

Cell-free DNA Comprises an In Vivo Nucleosome Footprint that Informs Its Tissues-Of-Origin.

Cell 2016 Jan;164(1-2):57-68

Department of Genome Sciences, University of Washington, Seattle, WA 98195, USA; Howard Hughes Medical Institute, Seattle, WA 98195, USA. Electronic address:

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http://www.cell.com/cms/attachment/2062302816/2064037364/mmc
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http://dx.doi.org/10.1016/j.cell.2015.11.050DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4715266PMC
January 2016

An essential cell cycle regulation gene causes hybrid inviability in Drosophila.

Science 2015 Dec;350(6267):1552-5

Basic Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA. Howard Hughes Medical Institute, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.

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Source
http://dx.doi.org/10.1126/science.aac7504DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703311PMC
December 2015