Javed Siddiqui

Javed Siddiqui

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Javed Siddiqui

Javed Siddiqui

Publications by authors named "Javed Siddiqui"

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Neurofilament is superior to cytokeratin 20 in supporting cutaneous origin for neuroendocrine carcinoma.

Histopathology 2019 Feb 5;74(3):504-513. Epub 2018 Dec 5.

Department of Pathology, Michigan Medicine/University of Michigan Health System, Ann Arbor, MI, USA.

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http://dx.doi.org/10.1111/his.13758DOI Listing
February 2019

Targeting Androgen Receptor and DNA Repair in Metastatic Castration-Resistant Prostate Cancer: Results From NCI 9012.

J Clin Oncol 2018 04 20;36(10):991-999. Epub 2017 Dec 20.

Maha Hussain, Robert H. Lurie Comprehensive Cancer Center, Northwestern University; Walter M. Stadler, University of Chicago, Chicago; Daniel H. Shevrin, NorthShore University Health System, Evanston, IL; Maha Hussain, Stephanie Daignault-Newton, Lakshmi P. Kunju, Javed Siddiqui, Yi-Mi Wu, Dan Robinson, Robert J. Lonigro, Xuhong Cao, Scott A. Tomlins, Rohit Mehra, David C. Smith, Megan V. Caram, and Arul M. Chinnaiyan, University of Michigan Comprehensive Cancer Center, Ann Arbor, MI; Przemyslaw W. Twardowski, City of Hope Cancer Center, Duarte; Felix Y. Feng, University of California San Francisco, San Francisco, CA; Costantine Albany, Simon Cancer Center, Indiana University, Indianapolis, IN; Mark N. Stein, Rutgers Cancer Institute of New Jersey, New Brunswick, NJ; Kathleen A. Cooney, University of Utah, Salt Lake City, UT; Bruce Montgomery, University of Washington, Seattle, WA; Emmanuel S. Antonarakis, Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, Baltimore, MD; Paul G. Corn, University of Texas MD Anderson Cancer Center, Houston, TX; Young E. Whang, Lineberger Comprehensive Cancer Center, University of North Carolina, Chapel Hill, NC; and Karen E. Knudsen, Thomas Jefferson University, Philadelphia, PA.

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http://dx.doi.org/10.1200/JCO.2017.75.7310DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075827PMC
April 2018

Nerve Growth Factor and Selected Cytokines in Women With and Without Vulvodynia.

J Low Genit Tract Dis 2018 Apr;22(2):139-146

University of Michigan, Department of Family Medicine, Ann Arbor, MI.

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http://dx.doi.org/10.1097/LGT.0000000000000377DOI Listing
April 2018

The utility of SDHB and FH immunohistochemistry in patients evaluated for hereditary paraganglioma-pheochromocytoma syndromes.

Hum Pathol 2018 01 24;71:47-54. Epub 2017 Oct 24.

Department of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109; Comprehensive Cancer Center, Michigan Medicine, Ann Arbor, MI; Michigan Center for Translational Pathology, Ann Arbor, MI 48109. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00468177173038
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http://dx.doi.org/10.1016/j.humpath.2017.10.013DOI Listing
January 2018

Programmed Death-ligand 1 Expression in Upper Tract Urothelial Carcinoma.

Eur Urol Focus 2017 10 13;3(4-5):502-509. Epub 2016 Dec 13.

Department of Pathology, University of Michigan Health System, Ann Arbor, MI, USA; Comprehensive Cancer Center, University of Michigan Health System, Ann Arbor, MI, USA; Michigan Center for Translational Pathology, Ann Arbor, MI, USA. Electronic address:

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http://dx.doi.org/10.1016/j.euf.2016.11.011DOI Listing
October 2017

Depletion of SAG/RBX2 E3 ubiquitin ligase suppresses prostate tumorigenesis via inactivation of the PI3K/AKT/mTOR axis.

Mol Cancer 2016 12 12;15(1):81. Epub 2016 Dec 12.

Division of Radiation and Cancer Biology, Department of Radiation Oncology, 4424B MS-1, 1301 Catherine Street, Ann Arbor, 48109, MI, USA.

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http://dx.doi.org/10.1186/s12943-016-0567-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5153812PMC
December 2016

The ubiquitin ligase TRIM25 targets ERG for degradation in prostate cancer.

Oncotarget 2016 Oct;7(40):64921-64931

Eugene McDermott Center for Human Growth and Development, University of Texas Southwestern Medical Center, Dallas, Texas, USA.

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http://dx.doi.org/10.18632/oncotarget.11915DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5323126PMC
October 2016

Prognostic Value of Percent Gleason Grade 4 at Prostate Biopsy in Predicting Prostatectomy Pathology and Recurrence.

J Urol 2016 08 23;196(2):405-11. Epub 2016 Feb 23.

Department of Pathology, University of Michigan Medical School, Ann Arbor, Michigan; Michigan Center for Translational Pathology, University of Michigan Medical School, Ann Arbor, Michigan; Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, Michigan. Electronic address:

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http://dx.doi.org/10.1016/j.juro.2016.01.120DOI Listing
August 2016

Urine TMPRSS2:ERG Plus PCA3 for Individualized Prostate Cancer Risk Assessment.

Eur Urol 2016 07 16;70(1):45-53. Epub 2015 May 16.

Michigan Center for Translational Pathology, Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA; Department of Urology, University of Michigan Medical School, Ann Arbor, MI, USA; Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, MI, USA; Department of Computational Medicine and Bioinformatics, University of Michigan Medical School, Ann Arbor, MI, USA; Howard Hughes Medical Institute, University of Michigan Medical School, Ann Arbor, MI, USA. Electronic address:

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http://dx.doi.org/10.1016/j.eururo.2015.04.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644724PMC
July 2016

Porocarcinomas harbor recurrent HRAS-activating mutations and tumor suppressor inactivating mutations.

Hum Pathol 2016 May 7;51:25-31. Epub 2016 Jan 7.

Department of Pathology, University of Michigan Health System, Ann Arbor, MI 48109; Michigan Center for Translational Pathology, University of Michigan Health System, Ann Arbor, MI 48109; Department of Urology, University of Michigan Health System, Ann Arbor, MI 48109; Comprehensive Cancer Center, University of Michigan Health System, Ann Arbor, MI 48109. Electronic address:

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http://dx.doi.org/10.1016/j.humpath.2015.12.015DOI Listing
May 2016

Expression of PDL1 (B7-H1) Before and After Neoadjuvant Chemotherapy in Urothelial Carcinoma.

Eur Urol Focus 2016 Feb 6;1(3):265-268. Epub 2015 Jun 6.

Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA; Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, MI, USA; Michigan Center for Translational Pathology, University of Michigan Medical School, Ann Arbor, MI, USA. Electronic address:

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http://dx.doi.org/10.1016/j.euf.2015.03.004DOI Listing
February 2016

Genomic Profiling of Penile Squamous Cell Carcinoma Reveals New Opportunities for Targeted Therapy.

Cancer Res 2015 Dec;75(24):5219-27

Department of Pathology, Michigan Center for Translational Pathology, University of Michigan, Ann Arbor, Michigan. Department of Urology, University of Michigan, Ann Arbor, Michigan. Comprehensive Cancer Center, University of Michigan, Ann Arbor, Michigan.

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http://cancerres.aacrjournals.org/content/75/24/5219.full.pd
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http://cancerres.aacrjournals.org/content/75/24/5219.full.pd
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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-15-1004DOI Listing
December 2015

Quantifying Gleason scores with photoacoustic spectral analysis: feasibility study with human tissues.

Biomed Opt Express 2015 Dec 9;6(12):4781-9. Epub 2015 Nov 9.

Department of Radiology, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA ; Department of Biomedical Engineering, University of Michigan, Ann Arbor, Michigan 48109, USA.

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http://dx.doi.org/10.1364/BOE.6.004781DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4679253PMC
December 2015

Cutaneous basal cell carcinosarcomas: evidence of clonality and recurrent chromosomal losses.

Hum Pathol 2015 May 14;46(5):690-7. Epub 2015 Jan 14.

Department of Pathology, University of Michigan Health System, Ann Arbor MI 48109; Department of Dermatology, University of Michigan Health System, Ann Arbor MI 48109.

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http://dx.doi.org/10.1016/j.humpath.2015.01.006DOI Listing
May 2015

Integrative clinical genomics of advanced prostate cancer.

Cell 2015 May;161(5):1215-1228

Michigan Center for Translational Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Department of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Department of Urology, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Howard Hughes Medical Institute, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2015.05.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4484602PMC
May 2015

Immunohistochemical staining characteristics of nephrogenic adenoma using the PIN-4 cocktail (p63, AMACR, and CK903) and GATA-3.

Am J Surg Pathol 2014 Dec;38(12):1664-71

Departments of *Pathology ‡Internal Medicine §Urology †Michigan Center for Translational Pathology ∥Comprehensive Cancer Center ¶Howard Hughes Medical Institute, University of Michigan Medical School, Ann Arbor, MI #Department of Anatomic Pathology, Cleveland Clinic, Cleveland, OH.

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http://dx.doi.org/10.1097/PAS.0000000000000267DOI Listing
December 2014

RNA biomarkers associated with metastatic progression in prostate cancer: a multi-institutional high-throughput analysis of SChLAP1.

Lancet Oncol 2014 Dec 17;15(13):1469-1480. Epub 2014 Nov 17.

Michigan Center for Translational Pathology, University of Michigan Medical School, Ann Arbor, MI, USA; Department of Radiation Oncology, University of Michigan Medical School, Ann Arbor, MI, USA; Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, MI, USA. Electronic address:

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http://dx.doi.org/10.1016/S1470-2045(14)71113-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559342PMC
December 2014

Small cell carcinoma in the parotid harboring Merkel cell polyomavirus.

Oral Surg Oral Med Oral Pathol Oral Radiol 2014 Dec 17;118(6):703-12. Epub 2014 Sep 17.

School of Dentistry, University of Michigan, Ann Arbor, MI. Electronic address:

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http://dx.doi.org/10.1016/j.oooo.2014.09.012DOI Listing
December 2014

A novel RNA in situ hybridization assay for the long noncoding RNA SChLAP1 predicts poor clinical outcome after radical prostatectomy in clinically localized prostate cancer.

Neoplasia 2014 Dec;16(12):1121-7

Department of Pathology, University of Michigan Health System, Ann Arbor, MI; Comprehensive Cancer Center, University of Michigan Health System, Ann Arbor, MI; Michigan Center for Translational Pathology, Ann Arbor, MI; Department of Urology, University of Michigan Health System, Ann Arbor, MI; Howard Hughes Medical Institute, Ann Arbor, MI. Electronic address:

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http://dx.doi.org/10.1016/j.neo.2014.11.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309259PMC
December 2014

Prostate cancer with Paneth cell-like neuroendocrine differentiation has recognizable histomorphology and harbors AURKA gene amplification.

Hum Pathol 2014 Oct 26;45(10):2136-43. Epub 2014 Jun 26.

Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell University, New York, NY 10065; Institute for Precision Medicine of Weill Medical College of Cornell University and New York Presbyterian Hospital, New York, NY 10065. Electronic address:

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http://dx.doi.org/10.1016/j.humpath.2014.06.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414025PMC
October 2014

Genetic ablation of metadherin inhibits autochthonous prostate cancer progression and metastasis.

Cancer Res 2014 Sep 29;74(18):5336-47. Epub 2014 Jul 29.

Department of Molecular Biology, Princeton University, Princeton, New Jersey. Tumor Progression and Genomic Instability Program, The Cancer Institute of New Jersey, New Brunswick, New Jersey.

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http://dx.doi.org/10.1158/0008-5472.CAN-14-1349DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167565PMC
September 2014

HRAS mutations are frequent in inverted urothelial neoplasms.

Hum Pathol 2014 Sep 18;45(9):1957-65. Epub 2014 Jun 18.

Michigan Center for Translational Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, USA; Department of Pathology, University of Michigan Medical School, Ann Arbor, MI 48109, USA. Electronic address:

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http://dx.doi.org/10.1016/j.humpath.2014.06.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4241848PMC
September 2014

Novel RNA hybridization method for the in situ detection of ETV1, ETV4, and ETV5 gene fusions in prostate cancer.

Appl Immunohistochem Mol Morphol 2014 Sep;22(8):e32-40

*Michigan Center for Translational Pathology Departments of †Pathology §Urology ‡Comprehensive Cancer Center ∥Howard Hughes Medical Institute, University of Michigan, Ann Arbor, MI.

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http://dx.doi.org/10.1097/PAI.0000000000000095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4159774PMC
September 2014

HOXB13 G84E-related familial prostate cancers: a clinical, histologic, and molecular survey.

Am J Surg Pathol 2014 May;38(5):615-26

Departments of *Pathology §Internal Medicine ¶Urology †Michigan Center for Translational Pathology ‡Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, MI ∥Howard Hughes Medical Institute, Chevy Chase, MD.

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http://dx.doi.org/10.1097/PAS.0000000000000090DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3988475PMC
May 2014

Evaluation of tissue PCA3 expression in prostate cancer by RNA in situ hybridization--a correlative study with urine PCA3 and TMPRSS2-ERG.

Mod Pathol 2014 Apr 27;27(4):609-20. Epub 2013 Sep 27.

1] Department of Pathology, University of Michigan Medical School, Ann Arbor, MI, USA [2] Michigan Center for Translational Pathology, University of Michigan Medical School, Ann Arbor, MI, USA [3] Comprehensive Cancer Center, University of Michigan Medical School, Ann Arbor, MI, USA.

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http://www.nature.com/articles/modpathol2013169
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http://dx.doi.org/10.1038/modpathol.2013.169DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3968238PMC
April 2014

Hereditary leiomyomatosis and renal cell carcinoma (HLRCC): a rapid autopsy report of metastatic renal cell carcinoma.

Am J Surg Pathol 2014 Apr;38(4):567-77

Departments of *Pathology #Urology †Internal Medicine, Division of Hematology and Oncology ‡Comprehensive Cancer Center, University of Michigan Health System ∥Michigan Center for Translational Pathology ¶Howard Hughes Medical Institute, Ann Arbor, MI §Department of Pathology, Memorial Sloan-Kettering Cancer Center, New York, NY.

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http://dx.doi.org/10.1097/PAS.0000000000000127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4117250PMC
April 2014

Primary urethral clear-cell adenocarcinoma: comprehensive analysis by surgical pathology, cytopathology, and next-generation sequencing.

Am J Pathol 2014 Mar 3;184(3):584-91. Epub 2014 Jan 3.

Department of Pathology, University of Michigan Health System, Ann Arbor, Michigan; Comprehensive Cancer Center, University of Michigan Health System, Ann Arbor, Michigan; Michigan Center for Translational Pathology, Ann Arbor, Michigan; Department of Urology, University of Michigan Health System, Ann Arbor, Michigan; Howard Hughes Medical Institute, Ann Arbor, Michigan.

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http://dx.doi.org/10.1016/j.ajpath.2013.11.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936309PMC
March 2014

A novel canine model for prostate cancer.

Prostate 2013 Jun 17;73(9):952-9. Epub 2013 Jan 17.

Department of Urology, University of Michigan, Ann Arbor, Michigan 48109-5940, USA.

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http://dx.doi.org/10.1002/pros.22642DOI Listing
June 2013

Usefulness of a monoclonal ERG/FLI1 antibody for immunohistochemical discrimination of Ewing family tumors.

Am J Clin Pathol 2013 Jun;139(6):771-9

Michigan Center for Translational Pathology, Department of Pathology,University of Michigan Medical School, Ann Arbor, MI 48104-5054, USA.

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http://dx.doi.org/10.1309/AJCPN4L1BMRQPEITDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662488PMC
June 2013

CCL11 (eotaxin-1): a new diagnostic serum marker for prostate cancer.

Prostate 2013 May 11;73(6):573-81. Epub 2012 Oct 11.

Department of Urology, The University of Michigan School of Medicine, Ann Arbor, Michigan, USA.

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http://dx.doi.org/10.1002/pros.22597DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594486PMC
May 2013

Trop-2 promotes prostate cancer metastasis by modulating β(1) integrin functions.

Cancer Res 2013 May 27;73(10):3155-67. Epub 2013 Mar 27.

Prostate Cancer Discovery and Development Program, Department of Cancer Biology, Thomas Jefferson University, Philadelphia, PA 19107, USA.

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http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
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http://dx.doi.org/10.1158/0008-5472.CAN-12-3266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3655712PMC
May 2013

Testing for the recurrent HOXB13 G84E germline mutation in men with clinical indications for prostate biopsy.

J Urol 2013 Mar 2;189(3):849-53. Epub 2012 Oct 2.

Division of Health Services Research, University of Michigan Medical School, Ann Arbor, Michigan 48109, USA.

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http://dx.doi.org/10.1016/j.juro.2012.09.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4193792PMC
March 2013

Circulating fibroblast-like cells in men with metastatic prostate cancer.

Prostate 2013 Jan 21;73(2):176-81. Epub 2012 Jun 21.

Brady Urological Institute, Johns Hopkins University School of Medicine, Baltimore, MD, USA.

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http://dx.doi.org/10.1002/pros.22553DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3482413PMC
January 2013

Investigation on tumor hypoxia in resectable primary prostate cancer as demonstrated by 18F-FAZA PET/CT utilizing multimodality fusion techniques.

Eur J Nucl Med Mol Imaging 2011 Oct 16;38(10):1816-23. Epub 2011 Jul 16.

Department of Radiology, Division of Nuclear Medicine, University of Michigan, 1500 E. Medical Center Drive, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1007/s00259-011-1876-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3259612PMC
October 2011

Characterization of bone metastases from rapid autopsies of prostate cancer patients.

Clin Cancer Res 2011 Jun 9;17(12):3924-32. Epub 2011 May 9.

Department of Internal Medicine and Urology, University of Michigan Medical School, 7303 Cancer Center, 1500 East Medical Center Drive, Ann Arbor, MI 48109, USA.

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http://dx.doi.org/10.1158/1078-0432.CCR-10-3120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3117947PMC
June 2011

Activation of NF-{kappa}B by TMPRSS2/ERG Fusion Isoforms through Toll-Like Receptor-4.

Cancer Res 2011 Feb 17;71(4):1325-33. Epub 2010 Dec 17.

Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, USA.

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http://dx.doi.org/10.1158/0008-5472.CAN-10-2210DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3041849PMC
February 2011

Alpha 1,3 fucosyltransferases are master regulators of prostate cancer cell trafficking.

Proc Natl Acad Sci U S A 2009 Nov 4;106(46):19491-6. Epub 2009 Nov 4.

Department of Dermatology, Harvard Skin Disease Research Center, Brigham and Women's Hospital, Boston, MA 02115, USA.

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http://dx.doi.org/10.1073/pnas.0906074106DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780742PMC
November 2009