Javed Khan

Javed Khan

UNVERIFIED PROFILE

Are you Javed Khan?   Register this Author

Register author
Javed Khan

Javed Khan

Publications by authors named "Javed Khan"

Are you Javed Khan?   Register this Author

100Publications

-Reads

EWS-FLI1 reprograms the metabolism of Ewing sarcoma cells via positive regulation of glutamine import and serine-glycine biosynthesis.

Mol Carcinog 2018 Oct 19;57(10):1342-1357. Epub 2018 Jun 19.

Functional Genetics Section, Genetics Branch, Center for Cancer Research (CCR), National Cancer Institute (NCI), Bethesda, Maryland.

View Article
October 2018

Oxidative removal of brilliant green by UV/SO, UV/HSO and UV/HO processes in aqueous media: A comparative study.

J Hazard Mater 2018 Sep 6;357:506-514. Epub 2018 Jun 6.

Environmental Engineering and Science Program, Department of Chemical and Environmental Engineering, University of Cincinnati, 705 Engineering Research Center, Cincinnati, OH, 45221-0012, United States; Nireas-International Water Research Centre, University of Cyprus, P.O. Box 20537, Nicosia, 1678, Cyprus. Electronic address:

View Article
September 2018

Integrative Bayesian Analysis Identifies Rhabdomyosarcoma Disease Genes.

Cell Rep 2018 Jul;24(1):238-251

Department of Pediatrics, Division of Hematology/Oncology, University of Texas Southwestern Medical Center, Dallas, TX; Harold C. Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX; Gill Center for Cancer and Blood Disorders, Children's Health, Children's Medical Center, Dallas, TX. Electronic address:

View Article
July 2018

A simple solvent extraction and ultra-performance liquid chromatography-tandem mass spectrometric method for the identification and quantification of rhodamine B in commercial lip balm samples.

Spectrochim Acta A Mol Biomol Spectrosc 2018 Jul 31;206:72-77. Epub 2018 Jul 31.

Department of Chemistry, College of Science, King Saud University, P.O. Box 2455, Riyadh 11451, Saudi Arabia.

View Article
July 2018

The SS18-SSX Fusion Oncoprotein Hijacks BAF Complex Targeting and Function to Drive Synovial Sarcoma.

Cancer Cell 2018 Jun 31;33(6):1128-1141.e7. Epub 2018 May 31.

Department of Pediatric Oncology, Dana-Farber Cancer Institute and Harvard Medical School, 450 Brookline Avenue, Boston, MA 02215, USA; Epigenomics Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA. Electronic address:

View Article
June 2018

Prevalence and Antibiotic Resistance Profiles of Campylobacter jejuni Isolated from Poultry Meat and Related Samples at Retail Shops in Northern India.

Foodborne Pathog Dis 2018 Apr 29;15(4):218-225. Epub 2018 Jan 29.

1 Department of Agricultural Microbiology, Faculty of Agricultural Sciences, Aligarh Muslim University (AMU) , Aligarh, India .

View Article
April 2018

Vangl2/RhoA Signaling Pathway Regulates Stem Cell Self-Renewal Programs and Growth in Rhabdomyosarcoma.

Cell Stem Cell 2018 Mar;22(3):414-427.e6

Molecular Pathology, Cancer Center, and Regenerative Medicine, Massachusetts General Hospital Research Institute, Boston, MA 02129, USA; Harvard Stem Cell Institute, Cambridge, MA 02139, USA. Electronic address:

View Article
March 2018

Negatively charged food additive dye "Allura Red" rapidly induces SDS-soluble amyloid fibril in beta-lactoglobulin protein.

Int J Biol Macromol 2018 Feb 8;107(Pt B):1706-1716. Epub 2017 Oct 8.

Molecular Biophysics and Biophysical Chemistry Group, Interdisciplinary Biotechnology Unit, Aligarh Muslim University, Aligarh, 202002, India.

View Article
February 2018

pH induced single step shift of hydrophobic patches followed by formation of an MG state and an amyloidogenic intermediate in Lima Bean Trypsin Inhibitor (LBTI).

Int J Biol Macromol 2017 Oct 10;103:111-119. Epub 2017 May 10.

Department of Biotechnology, Jamia Millia Islamia, New Delhi, India. Electronic address:

View Article
October 2017

Spectroscopic studies on the gemini surfactant mediated refolding of human serum albumin.

Int J Biol Macromol 2017 Sep 27;102:331-335. Epub 2017 Mar 27.

Interdisciplinary Biotechnology Unit, Aligarh Muslim University, Aligarh 202002, India. Electronic address:

View Article
September 2017

Identification of GPC2 as an Oncoprotein and Candidate Immunotherapeutic Target in High-Risk Neuroblastoma.

Cancer Cell 2017 09;32(3):295-309.e12

Division of Oncology and Center for Childhood Cancer Research, Children's Hospital of Philadelphia, Colket Translational Research Building, 3501 Civic Center Boulevard, Philadelphia, PA 19104, USA; Department of Pediatrics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address:

View Article
September 2017

Frequent inactivating germline mutations in DNA repair genes in patients with Ewing sarcoma.

Genet Med 2017 08 26;19(8):955-958. Epub 2017 Jan 26.

Genetics Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland, USA.

View Article
August 2017

Case report: value of gene expression profiling in the diagnosis of atypical neuroblastoma.

BMC Res Notes 2017 Aug 17;10(1):413. Epub 2017 Aug 17.

Division of Pediatric Hematology, Oncology and Stem Cell Transplantation, Department of Pediatrics and Adolescent Medicine, University Medical Center, Aachen, Germany.

View Article
August 2017

Paired Expression Analysis of Tumor Cell Surface Antigens.

Front Oncol 2017 21;7:173. Epub 2017 Aug 21.

Genetics Branch, National Cancer Institute, Center for Cancer Research, National Institutes of Health, Bethesda, MD, United States.

View Article
August 2017

The NOTCH1/SNAIL1/MEF2C Pathway Regulates Growth and Self-Renewal in Embryonal Rhabdomyosarcoma.

Cell Rep 2017 06;19(11):2304-2318

Department of Pathology, Massachusetts General Hospital, Boston, MA 02114, USA; Center of Cancer Research, Massachusetts General Hospital, Charlestown, MA 02129, USA; Harvard Stem Cell Institute, Boston, MA 02114, USA. Electronic address:

View Article
June 2017

Synthetic food additive dye "Tartrazine" triggers amorphous aggregation in cationic myoglobin.

Int J Biol Macromol 2017 May 24;98:277-286. Epub 2017 Jan 24.

Surfactant Research Chair, Department of Chemistry, King Saud University, PO Box-2455, Riyadh, 11451, Saudi Arabia.

View Article
May 2017

PAX3-FOXO1 is essential for tumour initiation and maintenance but not recurrence in a human myoblast model of rhabdomyosarcoma.

J Pathol 2017 Apr 1;241(5):626-637. Epub 2017 Mar 1.

Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

View Article
April 2017

Epigenetic siRNA and Chemical Screens Identify SETD8 Inhibition as a Therapeutic Strategy for p53 Activation in High-Risk Neuroblastoma.

Cancer Cell 2017 01;31(1):50-63

Cell and Molecular Biology Section, Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, CRC, 1-3940, 10 Center Drive MSC-1105, Bethesda, MD 20892, USA. Electronic address:

View Article
January 2017

Efficient Photocatalytic Degradation of Norfloxacin in Aqueous Media by Hydrothermally Synthesized Immobilized TiO/Ti Films with Exposed {001} Facets.

J Phys Chem A 2016 Dec 13;120(50):9916-9931. Epub 2016 Dec 13.

Department of Chemistry, COMSATS Institute of Information Technology , Abbottabad, 22060, Pakistan.

View Article
December 2016

A Case-control Study for the Assessment of Correlation of Denture-related Sores and Oral Cancer Risk.

J Contemp Dent Pract 2016 Nov 1;17(11):930-933. Epub 2016 Nov 1.

Pacific Dental College and Hospital, Udaipur, Rajasthan, India.

View Article
November 2016

Expression of Myofibroblasts in Oral Squamous Cell Carcinoma: An Immunohistochemical Study.

J Contemp Dent Pract 2016 Oct 1;17(10):857-860. Epub 2016 Oct 1.

Pacific Dental College and Hospital, Udaipur, Rajasthan, India.

View Article
October 2016

Degradation of quinolone antibiotic, norfloxacin, in aqueous solution using gamma-ray irradiation.

Environ Sci Pollut Res Int 2016 Jul 28;23(13):13155-68. Epub 2016 Mar 28.

Department of Chemistry, COMSATS Institute of Information Technology, Abbotabad, 22060, Pakistan.

View Article
July 2016

The Achilles' Heel of "Ultrastable" Hyperthermophile Proteins: Submillimolar Concentrations of SDS Stimulate Rapid Conformational Change, Aggregation, and Amyloid Formation in Proteins Carrying Overall Positive Charge.

Biochemistry 2016 07 6;55(28):3920-36. Epub 2016 Jul 6.

Centre for Protein Science, Design and Engineering (CPSDE), Department of Biological Sciences, Indian Institute of Science Education and Research (IISER) Mohali , Knowledge City, Sector 81, SAS Nagar, Punjab, India 140306.

View Article
July 2016

Pediatric Rhabdomyosarcoma.

Crit Rev Oncog 2015 ;20(3-4):227-43

Genetics Branch, Oncogenomics Section, Center for Cancer Research, National Institutes of Health, Bethesda, Maryland; Pediatric Oncology Branch, Center for Cancer Research, National Institutes of Health, Bethesda, Maryland.

View Article
June 2016

Gamma radiolytic decomposition of endosulfan in aerated solution: the role of carbonate radical.

Environ Sci Pollut Res Int 2016 Jun 16;23(12):12362-71. Epub 2016 Mar 16.

Radiation Chemistry Laboratory, National Centre of Excellence in Physical Chemistry, University of Peshawar, Peshawar, 25120, Pakistan.

View Article
June 2016

Comparative insight into surfactants mediated amyloidogenesis of lysozyme.

Int J Biol Macromol 2016 Feb 23;83:315-25. Epub 2015 Nov 23.

Interdisciplinary Biotechnology Unit, Aligarh Muslim University, Aligarh 202002, India. Electronic address:

View Article
February 2016

Precision Therapy for Pediatric Cancers.

JAMA Oncol 2016 Jan 28. Epub 2016 Jan 28.

Molecular Oncology Section, Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, Bethesda, Maryland.

View Article
January 2016

SLFN11 Is a Transcriptional Target of EWS-FLI1 and a Determinant of Drug Response in Ewing Sarcoma.

Clin Cancer Res 2015 Sep 16;21(18):4184-93. Epub 2015 Mar 16.

Laboratory of Molecular Pharmacology, Developmental Therapeutics Branch, NCI, NIH, Bethesda, Maryland.

View Article
September 2015

Identification of microRNAs specific for epithelial cell adhesion molecule-positive tumor cells in hepatocellular carcinoma.

Hepatology 2015 Sep 30;62(3):829-40. Epub 2015 Jun 30.

Laboratory of Human Carcinogenesis, Center for Cancer Research, National Cancer Institute, Bethesda, MD.

View Article
September 2015

Biophysical insight into the anti-amyloidogenic behavior of taurine.

Int J Biol Macromol 2015 Sep 22;80:375-84. Epub 2015 Jun 22.

Interdisciplinary Biotechnology Unit, Aligarh Muslim University, Aligarh 202002, India. Electronic address:

View Article
September 2015

CASC15-S Is a Tumor Suppressor lncRNA at the 6p22 Neuroblastoma Susceptibility Locus.

Cancer Res 2015 Aug 22;75(15):3155-66. Epub 2015 Jun 22.

Division of Oncology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania. Department of Pediatrics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania. The Abramson Family Cancer Research Institute, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania.

View Article
August 2015

Root-Cause Analytical Survey for Measles Outbreak: Vaccination or Vaccine?- A Study From Madhepura District, Bihar, India.

J Clin Diagn Res 2015 Jun 1;9(6):SC04-7. Epub 2015 Jun 1.

Ex Deputy Director, NCDC , New Delhi, India .

View Article
June 2015

Role of eaq⁻, ·OH and H· in radiolytic degradation of atrazine: a kinetic and mechanistic approach.

J Hazard Mater 2015 May 21;288:147-57. Epub 2014 Nov 21.

Radiation Chemistry Laboratory, National Centre of Excellence in Physical Chemistry, University of Peshawar, Peshawar 25120, Pakistan. Electronic address:

View Article
May 2015

Assessment of a panel of tumor markers for the differential diagnosis of benign and malignant effusions by well-based reverse phase protein array.

Diagn Pathol 2015 May 29;10:53. Epub 2015 May 29.

Laboratory of Pathology, National Cancer Institute, National Institutes of Health, Bethesda, MD, 20892, USA.

View Article
May 2015

The genetics of splicing in neuroblastoma.

Cancer Discov 2015 Apr 30;5(4):380-95. Epub 2015 Jan 30.

Department of Neurology, University of California, San Francisco, San Francisco, California. Department of Neurosurgery, University of California, San Francisco, San Francisco, California. Department of Pediatrics, University of California, San Francisco, San Francisco, California.

View Article
April 2015

Clonality and evolutionary history of rhabdomyosarcoma.

PLoS Genet 2015 Mar 13;11(3):e1005075. Epub 2015 Mar 13.

Genetics Branch, Oncogenomics Section, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, Maryland, United States of America; Pediatric Oncology Branch, Center for Cancer Research, National Institutes of Health, Bethesda, Maryland, United States of America.

View Article
March 2015

Kinetic and mechanism investigation on the gamma irradiation induced degradation of endosulfan sulfate.

Chemosphere 2015 Feb 18;121:18-25. Epub 2014 Nov 18.

Radiation Chemistry Laboratory, National Centre of Excellence in Physical Chemistry, University of Peshawar, Peshawar 25120, Pakistan.

View Article
February 2015

Germline CARD11 Mutation in a Patient with Severe Congenital B Cell Lymphocytosis.

J Clin Immunol 2015 Jan 29;35(1):32-46. Epub 2014 Oct 29.

Department of Pharmacology, Uniformed Services University of the Health Sciences, 4301 Jones Bridge Rd., Bethesda, MD, 20814, USA.

View Article
January 2015

Elucidating the interaction of limonene with bovine serum albumin: a multi-technique approach.

Mol Biosyst 2015 Jan 10;11(1):307-16. Epub 2014 Nov 10.

Interdisciplinary Biotechnology Unit, Aligarh Muslim University, Aligarh 202002, India.

View Article
January 2015

Clinicopathologic features of a second patient with Ewing-like sarcoma harboring CIC-FOXO4 gene fusion.

Am J Surg Pathol 2014 Dec;38(12):1724-5

*Department of Pathology, University of California, San Francisco San Francisco, CA †Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY ‡Genetics Branch §Laboratory of Pathology, Center for Cancer Research, National Cancer Institute, Bethesda, MD.

View Article
December 2014

Accommodating the cost of growth and swimming in fish-the applicability of exercise-induced growth to juvenile hapuku (Polyprion oxygeneios).

Front Physiol 2014 1;5:448. Epub 2014 Dec 1.

Leigh Marine Laboratory, Institute of Marine Science, The University of Auckland Auckland, New Zealand.

View Article
December 2014

Minimally invasive plate osteosynthesis for distal tibial fractures.

J Orthop Surg (Hong Kong) 2014 Dec;22(3):299-303

Department of Orthopaedics and Trauma Surgery, Kaski Sewa Hospital, Pokhara, Nepal.

View Article
December 2014

RAD51B Activity and Cell Cycle Regulation in Response to DNA Damage in Breast Cancer Cell Lines.

Breast Cancer (Auckl) 2014 12;8:135-44. Epub 2014 Oct 12.

Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.

View Article
November 2014

Expression quantitative trait loci and receptor pharmacology implicate Arg1 and the GABA-A receptor as therapeutic targets in neuroblastoma.

Cell Rep 2014 Nov 23;9(3):1034-46. Epub 2014 Oct 23.

Department of Neurology, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Pediatrics, University of California, San Francisco, San Francisco, CA 94143, USA; Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address:

View Article
November 2014

Pharmacologic profile of the Adnectin BMS-962476, a small protein biologic alternative to PCSK9 antibodies for low-density lipoprotein lowering.

J Pharmacol Exp Ther 2014 Aug 10;350(2):412-24. Epub 2014 Jun 10.

Molecular Discovery Technologies (T.M., G.C., D.S., S.L., K.R., R.D., F.D., M.G., J.M., G.D., M.W., J.K.), Applied Genomics (S.P.H.), and Cardiovascular Discovery Biology (F.L., H.M., D.M., B.M., R.A.P.), Bristol-Myers Squibb Research and Development, Princeton, New Jersey.

View Article
August 2014

PBX1 is a favorable prognostic biomarker as it modulates 13-cis retinoic acid-mediated differentiation in neuroblastoma.

Clin Cancer Res 2014 Aug 19;20(16):4400-12. Epub 2014 Jun 19.

Department of Oncology, Lombardi Comprehensive Cancer Center; and.

View Article
August 2014

Role of aqueous electron and hydroxyl radical in the removal of endosulfan from aqueous solution using gamma irradiation.

J Hazard Mater 2014 Aug 2;278:40-8. Epub 2014 Jun 2.

Radiation Chemistry Laboratory, National Centre of Excellence in Physical Chemistry, University of Peshawar, Peshawar 25120, Pakistan.

View Article
August 2014

Case report: a 37-year-old male with telangiectasias, polycythemia vera, perinephric fluid collections, and intrapulmonary shunting.

BMC Hematol 2014 22;14(1):11. Epub 2014 Jul 22.

Division of Hematology, Massachusetts General Hospital Cancer Center, 55 Fruit Street, Boston, MA 02114 USA.

View Article
August 2014

Aspiration in injections: should we continue or abandon the practice?

F1000Res 2014 10;3:157. Epub 2014 Jul 10.

Centre for Injection Safety Pakistan, Interactive Research & Development, Karachi, Pakistan; The Indus Hospital, Karachi, 75190, Pakistan.

View Article
July 2014

Saudi Guidelines on the Diagnosis and Treatment of Pulmonary Hypertension: Pregnancy in pulmonary hypertension.

Ann Thorac Med 2014 Jul;9(Suppl 1):S108-12

Prince Sultan Medical Military City, Riyadh, Saudi Arabia.

View Article
July 2014

Bioinformatic description of immunotherapy targets for pediatric T-cell leukemia and the impact of normal gene sets used for comparison.

Front Oncol 2014 10;4:134. Epub 2014 Jun 10.

Pediatric Oncology Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health , Bethesda, MD , USA.

View Article
June 2014

Protonation favors aggregation of lysozyme with SDS.

Soft Matter 2014 Apr;10(15):2591-9

Interdisciplinary Biotechnology Unit, Aligarh Muslim University, Aligarh 202002, India.

View Article
April 2014

A site for direct integrin αvβ6·uPAR interaction from structural modelling and docking.

J Struct Biol 2014 Mar 11;185(3):327-35. Epub 2014 Jan 11.

Department of Chemistry and Biomolecular Sciences, Macquarie University, Sydney, NSW, Australia; ARC Centre of Excellence in Bioinformatics, Macquarie University, Sydney, NSW, Australia; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore. Electronic address:

View Article
March 2014

Hydrophobicity alone can not trigger aggregation in protonated mammalian serum albumins.

Phys Chem Chem Phys 2014 Mar;16(11):5150-61

Interdisciplinary Biotechnology Unit, Aligarh Muslim University, Aligarh 202002, India.

View Article
March 2014

Comprehensive genomic analysis of rhabdomyosarcoma reveals a landscape of alterations affecting a common genetic axis in fusion-positive and fusion-negative tumors.

Cancer Discov 2014 Feb 23;4(2):216-31. Epub 2014 Jan 23.

1Pediatric Oncology Branch, Oncogenomics Section, Center for Cancer Research, NIH; 2Laboratory of Pathology, National Cancer Institute, Bethesda, Maryland; 3Broad Institute of MIT and Harvard, Cambridge; 4Medical Oncology and Center for Cancer Genome Discovery, Dana-Farber Cancer Institute; 5Department of Pathology, Harvard Medical School, Boston, Massachusetts; 6University of Nebraska Medical Center, Omaha, Nebraska; 7Department of Pediatrics, Division of Hematology/Oncology, University of Texas Southwestern Medical Center, Dallas, Texas; and 8Department of Pediatrics, Seattle Children's Hospital, Fred Hutchinson Cancer Research Center, University of Washington, Seattle, Washington; 9The Tumour Bank, The Children's Cancer Research Unit, The Children's Hospital at Westmead, Westmead, New South Wales, Australia; 10Department of Oncology, Hospital Sant Joan de Deu de Barcelona, Barcelona, Spain.

View Article
February 2014