Jasper H N Yik

Jasper H N Yik

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Jasper H N Yik

Jasper H N Yik

Publications by authors named "Jasper H N Yik"

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23Publications

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Flavopiridol Protects Bone Tissue by Attenuating RANKL Induced Osteoclast Formation.

Front Pharmacol 2018 3;9:174. Epub 2018 May 3.

Department of Orthopaedic Surgery, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou, China.

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http://dx.doi.org/10.3389/fphar.2018.00174DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944179PMC
May 2018

In-vitro and in-vivo imaging of MMP activity in cartilage and joint injury.

Biochem Biophys Res Commun 2015 May 26;460(3):741-6. Epub 2015 Mar 26.

Lawrence J. Ellison Musculoskeletal Research Center, Department of Orthopaedic Surgery, University of California Davis Medical Center, 4635 Second Avenue Suite 2000, Sacramento CA 95817, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbrc.2015.03.100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4426085PMC
May 2015

Brd4 and HEXIM1: multiple roles in P-TEFb regulation and cancer.

Biomed Res Int 2014 29;2014:232870. Epub 2014 Jan 29.

Expression Engineering Group, Bioprocessing Technology Institute, A∗STAR (Agency for Science, Technology and Research), 20 Biopolis Way, No. 06-01, Singapore 138668 ; Department of Microbiology, National University of Singapore, Block MD4, 5 Science Drive 2, Singapore 117597.

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http://dx.doi.org/10.1155/2014/232870DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3925632PMC
December 2014

Reply: To PMID 24470357.

Arthritis Rheumatol 2014 Dec;66(12):3526

University of California, Davis, Sacramento, CA.

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http://dx.doi.org/10.1002/art.38817DOI Listing
December 2014

Cartilage oligomeric matrix protein and its binding partners in the cartilage extracellular matrix: interaction, regulation and role in chondrogenesis.

Matrix Biol 2014 Jul 2;37:102-11. Epub 2014 Jul 2.

Department of Orthopaedic Surgery, Lawrence J. Ellison Musculoskeletal Research Center, University of California at Davis Medical Center, Sacramento, CA 95817, USA.

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http://dx.doi.org/10.1016/j.matbio.2014.06.001DOI Listing
July 2014

The Oncogene LRF Stimulates Proliferation of Mesenchymal Stem Cells and Inhibits Their Chondrogenic Differentiation.

Cartilage 2013 Oct;4(4):329-38

Department of Orthopaedic Surgery, Lawrence J. Ellison Musculoskeletal Research Center, University of California Davis Medical Center, Sacramento, CA, USA.

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http://dx.doi.org/10.1177/1947603513497570DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297155PMC
October 2013

Cartilage oligomeric matrix protein enhances osteogenesis by directly binding and activating bone morphogenetic protein-2.

Bone 2013 Jul 23;55(1):23-35. Epub 2013 Mar 23.

Lawrence J. Ellison Musculoskeletal Research Center, Department of Orthopaedic Surgery, University of California Davis Medical Center, 4635 Second Avenue Suite 2000, Sacramento CA 95817, USA.

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http://dx.doi.org/10.1016/j.bone.2013.03.007DOI Listing
July 2013

The oncogene LRF is a survival factor in chondrosarcoma and contributes to tumor malignancy and drug resistance.

Carcinogenesis 2012 Nov 30;33(11):2076-83. Epub 2012 Jul 30.

Department of Orthopaedic Surgery, Lawrence J. Ellison Musculoskeletal Research Center, University of California Davis Medical Center, Sacramento, CA 95817, USA.

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http://dx.doi.org/10.1093/carcin/bgs254DOI Listing
November 2012

Enhanced activity of transforming growth factor β1 (TGF-β1) bound to cartilage oligomeric matrix protein.

J Biol Chem 2011 Dec 22;286(50):43250-8. Epub 2011 Sep 22.

Lawrence J. Ellison Musculoskeletal Research Center, Department of Orthopaedic Surgery, University of California Davis Medical Center, Sacramento, California 95817, USA.

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http://dx.doi.org/10.1074/jbc.M111.234716DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234822PMC
December 2011

Tat competes with HEXIM1 to increase the active pool of P-TEFb for HIV-1 transcription.

Nucleic Acids Res 2007 6;35(6):2003-12. Epub 2007 Mar 6.

Department of Medicine, Rosalind Russell Medical Research Center, University of California at San Francisco, San Francisco, CA 94143-0703, USA.

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http://nar.oxfordjournals.org/content/35/6/2003.full-text-lo
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http://nar.oxfordjournals.org/lookup/doi/10.1093/nar/gkm063
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http://dx.doi.org/10.1093/nar/gkm063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1874611PMC
May 2007

The Yin and Yang of P-TEFb regulation: implications for human immunodeficiency virus gene expression and global control of cell growth and differentiation.

Microbiol Mol Biol Rev 2006 Sep;70(3):646-59

Department of Molecular and Cell Biology, University of California, Berkeley, California 94720-3202, USA.

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http://dx.doi.org/10.1128/MMBR.00011-06DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1594588PMC
September 2006

Recruitment of P-TEFb for stimulation of transcriptional elongation by the bromodomain protein Brd4.

Mol Cell 2005 Aug;19(4):535-45

Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, California 94720, USA.

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http://dx.doi.org/10.1016/j.molcel.2005.06.029DOI Listing
August 2005

Compensatory contributions of HEXIM1 and HEXIM2 in maintaining the balance of active and inactive positive transcription elongation factor b complexes for control of transcription.

J Biol Chem 2005 Apr 14;280(16):16368-76. Epub 2005 Feb 14.

Department of Molecular and Cell Biology, University of California, Berkeley, California 94720, USA.

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http://dx.doi.org/10.1074/jbc.M500912200DOI Listing
April 2005

Inhibition of P-TEFb (CDK9/Cyclin T) kinase and RNA polymerase II transcription by the coordinated actions of HEXIM1 and 7SK snRNA.

Mol Cell 2003 Oct;12(4):971-82

Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA.

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October 2003

The position of cysteine relative to the transmembrane domain is critical for palmitoylation of H1, the major subunit of the human asialoglycoprotein receptor.

J Biol Chem 2002 Dec 4;277(49):47305-12. Epub 2002 Oct 4.

Department of Biochemistry & Molecular Biology and the Oklahoma Center for Medical Glycobiology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73190, USA.

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http://dx.doi.org/10.1074/jbc.M208751200DOI Listing
December 2002

Nonpalmitoylated human asialoglycoprotein receptors recycle constitutively but are defective in coated pit-mediated endocytosis, dissociation, and delivery of ligand to lysosomes.

J Biol Chem 2002 Oct 8;277(43):40844-52. Epub 2002 Aug 8.

Department of Biochemistry & Molecular Biology, The Oklahoma Center for Medical Glycobiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73190, USA.

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http://dx.doi.org/10.1074/jbc.M204780200DOI Listing
October 2002

Palmitoylation-defective asialoglycoprotein receptors are normal in their cellular distribution and ability to bind ligand, but are defective in ligand uptake and degradation.

Biochem Biophys Res Commun 2002 Oct;297(4):980-6

Department of Biochemistry and Molecular Biology, Oklahoma Center for Medical Glycobiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73190, USA.

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October 2002

H2, the minor subunit of the human asialoglycoprotein receptor, trafficks intracellularly and forms homo-oligomers, but does not bind asialo-orosomucoid.

J Biol Chem 2002 Sep 27;277(38):35297-304. Epub 2002 Jun 27.

Department of Biochemistry and Molecular Biology, and The Oklahoma Center for Medical Glycobiology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73190, USA.

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http://dx.doi.org/10.1074/jbc.M205653200DOI Listing
September 2002

Glycans as endocytosis signals: the cases of the asialoglycoprotein and hyaluronan/chondroitin sulfate receptors.

Biochim Biophys Acta 2002 Sep;1572(2-3):341-63

Department of Biochemistry and Molecular Biology, and The Oklahoma Center for Medical Glycobiology, University of Oklahoma Health Sciences Center, Oklahoma City, OK 73190, USA.

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September 2002

The minor subunit splice variants, H2b and H2c, of the human asialoglycoprotein receptor are present with the major subunit H1 in different hetero-oligomeric receptor complexes.

J Biol Chem 2002 Jun 9;277(25):23076-83. Epub 2002 Apr 9.

Department of Biochemistry & Molecular Biology, and The Oklahoma Center for Medical Glycobiology, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma 73190, USA.

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http://dx.doi.org/10.1074/jbc.M202748200DOI Listing
June 2002