Publications by authors named "Jason Vander Heiden"

28Publications

Repertoire-wide phylogenetic models of B cell molecular evolution reveal evolutionary signatures of aging and vaccination.

Proc Natl Acad Sci U S A 2019 11 21;116(45):22664-22672. Epub 2019 Oct 21.

Department of Pathology, Yale School of Medicine, New Haven, CT 06520;

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http://dx.doi.org/10.1073/pnas.1906020116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6842591PMC
November 2019

The Repertoire Dissimilarity Index as a method to compare lymphocyte receptor repertoires.

BMC Bioinformatics 2017 Mar 7;18(1):155. Epub 2017 Mar 7.

Department of Microbiology and Immunology, Stanford University School of Medicine, Stanford, 94305, CA, USA.

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http://dx.doi.org/10.1186/s12859-017-1556-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5340033PMC
March 2017

A Model of Somatic Hypermutation Targeting in Mice Based on High-Throughput Ig Sequencing Data.

J Immunol 2016 11 5;197(9):3566-3574. Epub 2016 Oct 5.

Interdepartmental Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06511;

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http://dx.doi.org/10.4049/jimmunol.1502263DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5161250PMC
November 2016

The mutation patterns in B-cell immunoglobulin receptors reflect the influence of selection acting at multiple time-scales.

Philos Trans R Soc Lond B Biol Sci 2015 Sep;370(1676)

Department of Mathematics, Bar-Ilan University, Ramat Gan 5290002, Israel Gonda Brain Research Center, Bar-Ilan University, Ramat Gan 5290002, Israel

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http://rstb.royalsocietypublishing.org/lookup/doi/10.1098/rs
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http://dx.doi.org/10.1098/rstb.2014.0242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4528419PMC
September 2015

Salmonella Infection Drives Promiscuous B Cell Activation Followed by Extrafollicular Affinity Maturation.

Immunity 2015 Jul 14;43(1):120-31. Epub 2015 Jul 14.

Department of Immunology, University of Pittsburgh, Pittsburgh, PA 15261, USA; Department of Laboratory Medicine and Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2015.06.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523395PMC
July 2015

Change-O: a toolkit for analyzing large-scale B cell immunoglobulin repertoire sequencing data.

Bioinformatics 2015 Oct 10;31(20):3356-8. Epub 2015 Jun 10.

Interdepartmental Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06511, USA, Department of Pathology, Yale University School of Medicine, New Haven, CT 06511, USA and.

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http://dx.doi.org/10.1093/bioinformatics/btv359DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4793929PMC
October 2015

Influence of seasonal exposure to grass pollen on local and peripheral blood IgE repertoires in patients with allergic rhinitis.

J Allergy Clin Immunol 2014 Sep;134(3):604-12

Randall Division of Cell and Molecular Biophysics, King's College London, London, United Kingdom; Medical Research Council and Asthma UK Centre, Allergic Mechanisms in Asthma, London, United Kingdom.

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http://dx.doi.org/10.1016/j.jaci.2014.07.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4151999PMC
September 2014

pRESTO: a toolkit for processing high-throughput sequencing raw reads of lymphocyte receptor repertoires.

Bioinformatics 2014 Jul 10;30(13):1930-2. Epub 2014 Mar 10.

Interdepartmental Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06511, USA, Bioengineering Program, Faculty of Engineering, Bar-Ilan University, Ramat Gan 52900, Israel, Department of Pathology, Yale School of Medicine, New Haven, CT 06511, Department of Science Education, Hofstra North Shore-LIJ School of Medicine, Hofstra University, Hempstead, NY 11530, Department of Neurology, Yale School of Medicine, New Haven, CT 06511, Human and Translational Immunology Program, Yale School of Medicine, New Haven, CT 06511 and AbVitro Inc., Boston, MA 02210, USAInterdepartmental Program in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06511, USA, Bioengineering Program, Faculty of Engineering, Bar-Ilan University, Ramat Gan 52900, Israel, Department of Pathology, Yale School of Medicine, New Haven, CT 06511, Department of Science Education, Hofstra North Shore-LIJ School of Medicine, Hofstra University, Hempstead, NY 11530, Department of Neurology, Yale School of Medicine, New Haven, CT 06511, Human and Translational Immunology Program, Yale School of Medicine, New Haven, CT 06511 and AbVitro Inc., Boston, MA 02210, USA.

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http://dx.doi.org/10.1093/bioinformatics/btu138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4071206PMC
July 2014

Models of somatic hypermutation targeting and substitution based on synonymous mutations from high-throughput immunoglobulin sequencing data.

Front Immunol 2013 15;4:358. Epub 2013 Nov 15.

Bioengineering Program, Faculty of Engineering, Bar Ilan University , Ramat Gan , Israel ; Department of Pathology, Yale School of Medicine , New Haven, CT , USA.

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http://dx.doi.org/10.3389/fimmu.2013.00358DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3828525PMC
December 2013

Molecular, ethno-spatial epidemiology of leprosy in China: novel insights for tracing leprosy in endemic and non endemic provinces.

Infect Genet Evol 2013 Mar 4;14:361-8. Epub 2013 Jan 4.

Beijing Friendship Hospital - Affiliate of Capital University of Medical Sciences, Beijing Tropical Medicine Research Institute, 95 Yang An Road, Beijing 100050, China.

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http://dx.doi.org/10.1016/j.meegid.2012.12.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3668695PMC
March 2013

Serum metabolomics reveals higher levels of polyunsaturated fatty acids in lepromatous leprosy: potential markers for susceptibility and pathogenesis.

PLoS Negl Trop Dis 2011 Sep 6;5(9):e1303. Epub 2011 Sep 6.

Department of Microbiology, Immunology and Pathology, Colorado State University, Fort Collins, Colorado, United States of America.

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http://dx.doi.org/10.1371/journal.pntd.0001303DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3167790PMC
September 2011

Transmission of leprosy in Qiubei County, Yunnan, China: insights from an 8-year molecular epidemiology investigation.

Infect Genet Evol 2011 Mar 1;11(2):363-74. Epub 2010 Dec 1.

Beijing Friendship Hospital--Affiliate of Capital University of Medicial Sciences, Beijing Tropical Medicine Research Institute, 95 Yong An Road, Beijing 100050, China.

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http://dx.doi.org/10.1016/j.meegid.2010.11.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3085323PMC
March 2011