Jason P Lerch

Jason P Lerch

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Jason P Lerch

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MEMRI-based imaging pipeline for guiding preclinical studies in mouse models of sporadic medulloblastoma.

Magn Reson Med 2019 Aug 12. Epub 2019 Aug 12.

Skirball Institute of Biomolecular Medicine, New York University School of Medicine, New York, New York.

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http://dx.doi.org/10.1002/mrm.27904DOI Listing
August 2019

Sex-biased trajectories of amygdalo-hippocampal morphology change over human development.

Neuroimage 2019 Aug 27:116122. Epub 2019 Aug 27.

Developmental Neurogenomics Unit, Human Genetics Branch, National Institute of Mental Health, Bethesda, MD, 20892, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuroimage.2019.116122DOI Listing
August 2019

Fetal brain sparing in a mouse model of chronic maternal hypoxia.

J Cereb Blood Flow Metab 2019 Jun 22;39(6):1172-1184. Epub 2017 Dec 22.

1 Mouse Imaging Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1177/0271678X17750324DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6547196PMC
June 2019

Haploinsufficiency of autism causative gene impairs olfactory discrimination and neuronal activation of the olfactory system in mice.

Mol Autism 2019 11;10. Epub 2019 Feb 11.

1Institute of Molecular Biology, Academia Sinica, 128, Academia Rd., Sec. 2, Taipei, 11529 Taiwan.

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http://dx.doi.org/10.1186/s13229-019-0257-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6371489PMC
April 2019

Structural covariance of brain region volumes is associated with both structural connectivity and transcriptomic similarity.

Neuroimage 2018 10 18;179:357-372. Epub 2018 May 18.

Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada; Mouse Imaging Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S10538119183043
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http://dx.doi.org/10.1016/j.neuroimage.2018.05.028DOI Listing
October 2018

Sensitive Periods for Cerebellar-Mediated Autistic-like Behaviors.

Cell Rep 2018 Oct;25(2):357-367.e4

F.M. Kirby Neurobiology Center, Department of Neurology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S22111247183148
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http://dx.doi.org/10.1016/j.celrep.2018.09.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6226056PMC
October 2018

Species-conserved SYNGAP1 phenotypes associated with neurodevelopmental disorders.

Mol Cell Neurosci 2018 09 24;91:140-150. Epub 2018 Mar 24.

Graduate School of Chemical and Biological Sciences, The Scripps Research Institute, Jupiter, FL, United States; Department of Neuroscience, The Scripps Research Institute, Jupiter, FL, United States. Electronic address:

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http://dx.doi.org/10.1016/j.mcn.2018.03.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6128754PMC
September 2018

Regional brain volume changes following chronic antipsychotic administration are mediated by the dopamine D2 receptor.

Neuroimage 2018 08 26;176:226-238. Epub 2018 Apr 26.

Department of Psychiatry & Integrated Program in Neuroscience, McGill University, 845 Sherbrooke St W, Montreal, QC, H3A 0G4 Canada; Sorbonne University, Neuroscience Paris Seine, CNRS UMR 8246, INSERM U 1130, UPMC Univ Paris 06, UM119, 75005, Paris, France. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10538119183036
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http://dx.doi.org/10.1016/j.neuroimage.2018.04.054DOI Listing
August 2018

Impact of X/Y genes and sex hormones on mouse neuroanatomy.

Neuroimage 2018 06 2;173:551-563. Epub 2018 Mar 2.

Division of Endocrinology, The Hospital for Sick Children, 555 University Avenue, Toronto, ON, M5G 1X8, Canada; Institute of Medical Science, Faculty of Medicine, University of Toronto, Medical Sciences Building, 1 King's College Circle, Room 2374, Toronto, Ontario, M5S 1A8, Canada; Department of Paediatrics, The University of Toronto, 555 University Avenue, Toronto, Ontario, M5G 1X8, Canada; Department of Physiology, The University of Toronto, Medical Sciences Building, 1 King's College Circle, Toronto, Ontario, M5S 1A8, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.neuroimage.2018.02.051DOI Listing
June 2018

Continuous manganese delivery via osmotic pumps for manganese-enhanced mouse MRI does not impair spatial learning but leads to skin ulceration.

Neuroimage 2018 06 2;173:411-420. Epub 2018 Mar 2.

Mouse Imaging Centre, The Hospital for Sick Children, 25 Orde Street, Toronto, ON, M5T 3H7, Canada; Department of Medical Biophysics, University of Toronto, 101 College Street Suite 15-701, Toronto, ON, M5G 1L7, Canada.

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http://dx.doi.org/10.1016/j.neuroimage.2018.02.046DOI Listing
June 2018

MRI to Assess Neurological Function.

Curr Protoc Mouse Biol 2018 Jun 22;8(2):e44. Epub 2018 May 22.

Mouse Imaging Centre, The Hospital for Sick Children, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/cpmo.44DOI Listing
June 2018

BDNF-Dependent Effects on Amygdala-Cortical Circuitry and Depression Risk in Children and Youth.

Cereb Cortex 2018 05;28(5):1760-1770

Research Imaging Centre, Campbell Family Mental Health Institute, Centre for Addiction and Mental Health, Toronto, Ontario, Canada M5T 1R8.

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http://dx.doi.org/10.1093/cercor/bhx086DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5907350PMC
May 2018

Neuroanatomical phenotypes in mental illness: identifying convergent and divergent cortical phenotypes across autism, ADHD and schizophrenia.

J Psychiatry Neurosci 2018 05;43(3):201-212

From the Schulich School of Medicine and Dentistry, Western University, London, Ont., Canada (Park); the Cerebral Imaging Centre, Douglas Mental Health University Institute, Montreal, Que., Canada (Park, Chakravarty); the Child Psychiatry Branch, National Institute of Mental Health, Bethesda, MD, USA (Raznahan); the Section on Neurobehavioral Clinical Research, Social and Behavioral Research Branch, National Human Genome Research Institute, Bethesda, MD, USA (Shaw); the Intramural Program of the National Institute of Mental Health, Bethesda, MD, USA (Shaw); the Program in Neuroscience and Mental Health, Hospital for Sick Children, Toronto, Ont., Canada (Lerch); and the Departments of Psychiatry and Biomedical Engineering, McGill University, Montreal, Que., Canada (Chakravarty).

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915241PMC
May 2018

Mental flexibility: An MEG investigation in typically developing children.

Brain Cogn 2018 02 20;120:58-66. Epub 2017 Oct 20.

Institute of Medical Science, Faculty of Medicine, University of Toronto, Canada; Neurosciences and Mental Health, SickKids Research Institute, Toronto, Canada; Division of Neurology, Hospital for Sick Children, Toronto, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.bandc.2017.10.001DOI Listing
February 2018

Neuroanatomical phenotypes in mental illness: identifying convergent and divergent cortical phenotypes across autism, ADHD and schizophrenia.

J Psychiatry Neurosci 2018 Feb 5;43(2):170094. Epub 2018 Feb 5.

From the Schulich School of Medicine and Dentistry, Western University, London, Ont., Canada (Park); the Cerebral Imaging Centre, Douglas Mental Health University Institute, Montreal, Que., Canada (Park, Chakravarty); the Child Psychiatry Branch, National Institute of Mental Health, Bethesda, MD, USA (Raznahan); the Section on Neurobehavioral Clinical Research, Social and Behavioral Research Branch, National Human Genome Research Institute, Bethesda, MD, USA (Shaw); the Intramural Program of the National Institute of Mental Health, Bethesda, MD, USA (Shaw); the Program in Neuroscience and Mental Health, Hospital for Sick Children, Toronto, Ont., Canada (Lerch); and the Departments of Psychiatry and Biomedical Engineering, McGill University, Montreal, Que., Canada (Chakravarty).

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http://dx.doi.org/10.1503/jpn.170094DOI Listing
February 2018

Development of short-range white matter in healthy children and adolescents.

Hum Brain Mapp 2018 01 14;39(1):204-217. Epub 2017 Oct 14.

Neurosciences and Mental Health, The Hospital for Sick Children, Toronto, Ontario.

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http://dx.doi.org/10.1002/hbm.23836DOI Listing
January 2018

Spatial gene expression analysis of neuroanatomical differences in mouse models.

Neuroimage 2017 12 4;163:220-230. Epub 2017 Sep 4.

Mouse Imaging Centre, Hospital for Sick Children, Toronto, ON, Canada; Department of Medical Biophysics, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1016/j.neuroimage.2017.08.065DOI Listing
December 2017

Distinct cerebellar foliation anomalies in a CHD7 haploinsufficient mouse model of CHARGE syndrome.

Am J Med Genet C Semin Med Genet 2017 12 23;175(4). Epub 2017 Nov 23.

Centre for Craniofacial and Regenerative Biology, King's College London, London, United Kingdom.

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http://doi.wiley.com/10.1002/ajmg.c.31595
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http://dx.doi.org/10.1002/ajmg.c.31595DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5765394PMC
December 2017

Systemic inflammation combined with neonatal cerebellar haemorrhage aggravates long-term structural and functional outcomes in a mouse model.

Brain Behav Immun 2017 Nov 27;66:257-276. Epub 2017 Jul 27.

Centre for Molecular Medicine and Therapeutics, Vancouver, BC, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.bbi.2017.07.013DOI Listing
November 2017

Foxp1 regulation of neonatal vocalizations via cortical development.

Genes Dev 2017 10 14;31(20):2039-2055. Epub 2017 Nov 14.

Department of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.

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http://dx.doi.org/10.1101/gad.305037.117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5733496PMC
October 2017

Repeated exposure to sucrose for procedural pain in mouse pups leads to long-term widespread brain alterations.

Pain 2017 08;158(8):1586-1598

aDepartment of Pediatrics, University of British Columbia, Vancouver, BC, Canada bBC Children's Hospital Research Institute, Vancouver, BC, Canada cCentre for Molecular Medicine and Therapeutics, Vancouver, BC, Canada dDepartment of Psychiatry, Developmental Neuroscience Division, Nurture Science Program, Columbia University, New York, NY, USA eMouse Imaging Centre, Hospital for Sick Children, Toronto, ON, Canada fDepartment of Medical Biophysics, University of Toronto, Toronto, ON, Canada gDepartment of Occupational Science & Occupational Therapy, University of British Columbia, Vancouver, BC, Canada.

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http://dx.doi.org/10.1097/j.pain.0000000000000961DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5539923PMC
August 2017

Behavioral and neuroanatomical analyses in a genetic mouse model of 2q13 duplication.

Genes Cells 2017 May 29;22(5):436-451. Epub 2017 Mar 29.

RIKEN Brain Science Institute (BSI), Wako, Saitama, 351-0198, Japan.

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http://dx.doi.org/10.1111/gtc.12487DOI Listing
May 2017

Language Ability Predicts Cortical Structure and Covariance in Boys with Autism Spectrum Disorder.

Cereb Cortex 2017 03;27(3):1849-1862

International Laboratory for Brain Music and Sound Research (BRAMS), Université de Montréal, Montréal, Quebec, Canada H2V 2J2.

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http://dx.doi.org/10.1093/cercor/bhw024DOI Listing
March 2017

Studying neuroanatomy using MRI.

Nat Neurosci 2017 Feb;20(3):314-326

Oxford Centre for Functional MRI of the Brain (FMRIB), University of Oxford, Oxford, UK.

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http://dx.doi.org/10.1038/nn.4501DOI Listing
February 2017

Imaging sex/gender and autism in the brain: Etiological implications.

J Neurosci Res 2017 01;95(1-2):380-397

Autism Research Centre, Department of Psychiatry, University of Cambridge, Cambridge, United Kingdom.

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http://doi.wiley.com/10.1002/jnr.23948
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http://dx.doi.org/10.1002/jnr.23948DOI Listing
January 2017

Widespread Volumetric Brain Changes following Tooth Loss in Female Mice.

Front Neuroanat 2016 9;10:121. Epub 2017 Jan 9.

University of Toronto Centre for the Study of Pain, University of TorontoToronto, ON, Canada; Faculty of Dentistry, University of TorontoToronto, ON, Canada; Department of Physiology, Faculty of Medicine, University of TorontoToronto, ON, Canada.

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http://dx.doi.org/10.3389/fnana.2016.00121DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5220047PMC
January 2017

A Diffusion Tensor Imaging Study in Children With ADHD, Autism Spectrum Disorder, OCD, and Matched Controls: Distinct and Non-Distinct White Matter Disruption and Dimensional Brain-Behavior Relationships.

Am J Psychiatry 2016 Dec 1;173(12):1213-1222. Epub 2016 Jul 1.

From the Centre for Brain and Mental Health and the Department of Diagnostic Imaging, the Hospital for Sick Children, University of Toronto; the Department of Psychology, University of Toronto; the Department of Psychiatry, the Department of Medical Biophysics, the Department of Pediatrics, and the Department of Medical Imaging, Faculty of Medicine, University of Toronto; the Holland Bloorview Kids Rehabilitation Hospital, Bloorview Research Institute, University of Toronto; the Margaret and Wallace McCain Centre for Child, Youth & Family Mental Health and the Kimel Family Translational Imaging-Genetics Lab, Campbell Family Mental Health Research Institute, Centre for Addiction and Mental Health (CAMH), University of Toronto; the Division of Child and Adolescent Psychiatry, Department of Psychiatry and Psychology, Mayo Clinic, Rochester, Minn.; the Pediatric OCD Consultation Service, Anxiety Treatment and Research Centre, St. Joseph's HealthCare, McMaster University, Hamilton, Ont., Canada; and the Mathison Centre for Mental Health Research and Education, Hotchkiss Brain Institute, the Department of Psychiatry, and the Department of Medical Genetics, Cumming School of Medicine, University of Calgary, Calgary, Alta., Canada.

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http://dx.doi.org/10.1176/appi.ajp.2016.15111435DOI Listing
December 2016

Variability of brain anatomy for three common mouse strains.

Neuroimage 2016 Nov 1;142:656-662. Epub 2016 Apr 1.

Mouse Imaging Centre, Hospital for Sick Children, Toronto, Ontario, Canada; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.neuroimage.2016.03.069DOI Listing
November 2016

Reduced cerebrovascular reserve is regionally associated with cortical thickness reductions in children with sickle cell disease.

Brain Res 2016 07 26;1642:263-269. Epub 2016 Mar 26.

Physiology and Experimental Medicine, The Hospital for Sick Children, Toronto, ON, Canada M5G0A4; Departmentment of Medical Imaging, University of Toronto, Toronto, ON, Canada M5T1W7. Electronic address:

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http://dx.doi.org/10.1016/j.brainres.2016.03.041DOI Listing
July 2016

Comparing homologous microscopic sections from multiple embryos using HREM.

Dev Biol 2016 07 18;415(1):1-5. Epub 2016 May 18.

The Francis Crick Institute Mill Hill Laboratory, London, UK.

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http://dx.doi.org/10.1016/j.ydbio.2016.05.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278891PMC
July 2016

Neuroanatomic Differences Associated With Stress Susceptibility and Resilience.

Biol Psychiatry 2016 May 18;79(10):840-849. Epub 2015 Aug 18.

Ludmer Centre for Neuroinformatics and Mental Health, Douglas Mental Health University Institute, McGill University, Montreal, Quebec, Canada; Singapore Institute for Clinical Sciences, Singapore. Electronic address:

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http://dx.doi.org/10.1016/j.biopsych.2015.08.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885767PMC
May 2016

The developing human brain: age-related changes in cortical, subcortical, and cerebellar anatomy.

Brain Behav 2016 04 22;6(4):e00457. Epub 2016 Mar 22.

Diagnostic Imaging Research The Hospital for Sick Children University of Toronto 555 University Avenue Toronto Ontario M5G 1X8 Canada.

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http://dx.doi.org/10.1002/brb3.457DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4802426PMC
April 2016

An Allometric Analysis of Sex and Sex Chromosome Dosage Effects on Subcortical Anatomy in Humans.

J Neurosci 2016 Feb;36(8):2438-48

Developmental Neurogenomics Unit, Child Psychiatry Branch, National Institute of Mental Health, National Institutes of Health, Bethesda, Maryland 20892.

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http://dx.doi.org/10.1523/JNEUROSCI.3195-15.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4764663PMC
February 2016

Deep brain stimulation of the ventromedial prefrontal cortex causes reorganization of neuronal processes and vasculature.

Neuroimage 2016 Jan 23;125:422-427. Epub 2015 Oct 23.

Program in Neuroscience and Mental Health, The Hospital for Sick Children, Canada; Mouse Imaging Centre (MICe), The Hospital for Sick Children, Canada; Department of Medical Biophysics, University of Toronto, Canada.

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http://dx.doi.org/10.1016/j.neuroimage.2015.10.049DOI Listing
January 2016

White and Gray Matter Abnormalities After Cranial Radiation in Children and Mice.

Int J Radiat Oncol Biol Phys 2015 Nov 4;93(4):882-91. Epub 2015 Aug 4.

Department of Neurosciences & Mental Health, Hospital for Sick Children, Toronto, Ontario, Canada; Department of Paediatrics, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.ijrobp.2015.07.2293DOI Listing
November 2015

Structural Gray Matter Differences During Childhood Development in Autism Spectrum Disorder: A Multimetric Approach.

Pediatr Neurol 2015 Oct 25;53(4):350-9. Epub 2015 Jun 25.

International Laboratory for Brain Music and Sound Research (BRAMS), FAS, Université de Montréal, Montréal, Quebec, Canada; Montreal Neurological Institute, Faculty of Medicine, McGill University, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1016/j.pediatrneurol.2015.06.013DOI Listing
October 2015

4D atlas of the mouse embryo for precise morphological staging.

Development 2015 Oct;142(20):3583-91

Mouse Imaging Centre, Hospital for Sick Children, Toronto, Ontario, M5T 3H7, Canada Department of Medical Biophysics, University of Toronto, Toronto, Ontario, M5G 1L7, Canada.

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http://dx.doi.org/10.1242/dev.125872DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6514395PMC
October 2015

4D MEMRI atlas of neonatal FVB/N mouse brain development.

Neuroimage 2015 Sep 30;118:49-62. Epub 2015 May 30.

Skirball Institute of Biomolecular Medicine, New York University School of Medicine, New York, NY, USA; Biomedical Imaging, New York University School of Medicine, New York, NY, USA; Molecular Biophysics Graduate Programs, New York University School of Medicine, New York, NY, USA; Department of Radiology, New York University School of Medicine, New York, NY, USA; Department of Pathology, New York University School of Medicine, New York, NY, USA. Electronic address:

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http://dx.doi.org/10.1016/j.neuroimage.2015.05.029DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4554969PMC
September 2015

Personality disorder symptomatology is associated with anomalies in striatal and prefrontal morphology.

Front Hum Neurosci 2015 31;9:472. Epub 2015 Aug 31.

Research Imaging Centre, Centre for Addiction and Mental Health, Toronto ON, Canada ; Cerebral Imaging Centre, Douglas Mental Health University Institute, Verdun QC, Canada ; Department of Psychiatry and Biomedical Engineering, McGill University, Montreal QC, Canada.

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http://dx.doi.org/10.3389/fnhum.2015.00472DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4553386PMC
September 2015

Whole-brain mapping of behaviourally induced neural activation in mice.

Brain Struct Funct 2015 Jul 24;220(4):2043-57. Epub 2014 Apr 24.

Mouse Imaging Centre, The Hospital for Sick Children, 25 Orde St., Toronto, ON M5T 3H7, Canada,

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http://dx.doi.org/10.1007/s00429-014-0774-0DOI Listing
July 2015

MRI-detectable changes in mouse brain structure induced by voluntary exercise.

Neuroimage 2015 Jun 21;113:175-83. Epub 2015 Mar 21.

Mouse Imaging Centre, The Hospital for Sick Children, Toronto, Ontario, Canada; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.neuroimage.2015.03.036DOI Listing
June 2015

Gray- and white-matter anatomy of absolute pitch possessors.

Cereb Cortex 2015 May 4;25(5):1379-88. Epub 2013 Dec 4.

Center of Functionally Integrative Neuroscience, University of Aarhus, Aarhus 8000, Denmark The Royal Academy of Music, Aarhus/Aalborg 8000, Denmark.

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https://academic.oup.com/cercor/article-lookup/doi/10.1093/c
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http://dx.doi.org/10.1093/cercor/bht334DOI Listing
May 2015

Loss of T cells influences sex differences in behavior and brain structure.

Brain Behav Immun 2015 May 26;46:249-60. Epub 2015 Feb 26.

Psychiatry & Behavioural Neurosciences, McMaster Univ., Hamilton, ON, Canada; Brain-Body Institute, St. Joseph's Healthcare, Hamilton, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.bbi.2015.02.016DOI Listing
May 2015

Further neuroimaging evidence for the deficit subtype of schizophrenia: a cortical connectomics analysis.

JAMA Psychiatry 2015 May;72(5):446-55

Kimel Family Translational Imaging Genetics Laboratory, Research Imaging Centre, Centre for Addiction and Mental Health, Toronto, Ontario, Canada2Schizophrenia Division of the Complex Mental Illness Program, Centre for Addiction and Mental Health, Toronto.

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http://dx.doi.org/10.1001/jamapsychiatry.2014.3020DOI Listing
May 2015

Striatal shape abnormalities as novel neurodevelopmental endophenotypes in schizophrenia: a longitudinal study.

Hum Brain Mapp 2015 Apr 11;36(4):1458-69. Epub 2014 Dec 11.

Cerebral Imaging Centre, Douglas Mental Health University Institute, Verdun, Canada; Department of Psychiatry, McGill University, Montreal, Canada; Department of Biomedical Engineering, McGill University, Montreal, Canada.

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http://dx.doi.org/10.1002/hbm.22715DOI Listing
April 2015

Environmental enrichment is associated with rapid volumetric brain changes in adult mice.

Neuroimage 2015 Apr 14;109:190-8. Epub 2015 Jan 14.

Mouse Imaging Centre, Hospital for Sick Children, Toronto, Ontario, Canada; Program in Neurosciences and Mental Health, The Hospital for Sick Children, Toronto, Ontario, Canada; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1016/j.neuroimage.2015.01.027DOI Listing
April 2015

The trajectory of gray matter development in Broca's area is abnormal in people who stutter.

Front Hum Neurosci 2015 3;9:89. Epub 2015 Mar 3.

Department of Speech-Language Pathology, University of Toronto Toronto, ON, Canada.

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http://dx.doi.org/10.3389/fnhum.2015.00089DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4347452PMC
March 2015

Rotarod training in mice is associated with changes in brain structure observable with multimodal MRI.

Neuroimage 2015 Feb 10;107:182-189. Epub 2014 Dec 10.

Mouse Imaging Centre, Hospital for Sick Children, Toronto, Ontario, Canada; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada; Program in Neurosciences and Mental Health, The Hospital for Sick Children, Toronto, ON, Canada.

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https://linkinghub.elsevier.com/retrieve/pii/S10538119140099
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http://dx.doi.org/10.1016/j.neuroimage.2014.12.003DOI Listing
February 2015

Illness denial in schizophrenia spectrum disorders: a function of left hemisphere dominance.

Hum Brain Mapp 2015 Jan 11;36(1):213-25. Epub 2014 Sep 11.

Multimodal Imaging Group, Research Imaging Centre, Centre for Addiction & Mental Health, Toronto, Ontario, Canada; Department of Psychiatry, University of Toronto, Toronto, Ontario, Canada.

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http://doi.wiley.com/10.1002/hbm.22624
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http://dx.doi.org/10.1002/hbm.22624DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4268179PMC
January 2015

Multi-atlas segmentation of the whole hippocampus and subfields using multiple automatically generated templates.

Neuroimage 2014 Nov 29;101:494-512. Epub 2014 Apr 29.

Kimel Family Translational Imaging-Genetics Lab, Centre for Addiction and Mental Health, Toronto, ON, Canada; Department of Psychiatry, University of Toronto, Toronto, ON, Canada; Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, ON, Canada; Rotman Research Institute, Baycrest, Toronto, ON, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.neuroimage.2014.04.054DOI Listing
November 2014

Label-fusion-segmentation and deformation-based shape analysis of deep gray matter in multiple sclerosis: the impact of thalamic subnuclei on disability.

Hum Brain Mapp 2014 Aug 7;35(8):4193-203. Epub 2014 Feb 7.

Department of Neurology, University Hospital Basel, Switzerland; Medical Image Analysis Center, University Hospital Basel, Switzerland.

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http://dx.doi.org/10.1002/hbm.22470DOI Listing
August 2014

Pydpiper: a flexible toolkit for constructing novel registration pipelines.

Front Neuroinform 2014 30;8:67. Epub 2014 Jul 30.

Mouse Imaging Centre, Hospital for Sick Children Toronto, ON, Canada ; Department of Medical Biophysics, University of Toronto Toronto, ON, Canada.

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http://dx.doi.org/10.3389/fninf.2014.00067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4115634PMC
August 2014

Derivation of high-resolution MRI atlases of the human cerebellum at 3T and segmentation using multiple automatically generated templates.

Neuroimage 2014 Jul 21;95:217-31. Epub 2014 Mar 21.

Kimel Family Translational Imaging Genetics Research Laboratory, Research Imaging Centre, Centre for Addiction and Mental Health, Toronto, Canada; Department of Psychiatry, University of Toronto, Toronto, Canada; Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10538119140018
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http://dx.doi.org/10.1016/j.neuroimage.2014.03.037DOI Listing
July 2014

Automatic anatomical labeling of the complete cerebral vasculature in mouse models.

Neuroimage 2014 Jul 28;95:117-28. Epub 2014 Mar 28.

Department of Medical Biophysics, University of Toronto, Toronto, Ontario M5G 2M9, Canada; Mouse Imaging Centre, The Hospital for Sick Children, 25 Orde St., Toronto, Ontario M5T 3H7, Canada.

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http://dx.doi.org/10.1016/j.neuroimage.2014.03.044DOI Listing
July 2014

Mapping the development of the basal ganglia in children with attention-deficit/hyperactivity disorder.

J Am Acad Child Adolesc Psychiatry 2014 Jul 20;53(7):780-9.e11. Epub 2014 May 20.

Research Imaging Centre, Centre for Addiction and Mental Health, Toronto, Canada.

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http://dx.doi.org/10.1016/j.jaac.2014.05.003DOI Listing
July 2014

Automated pipeline for anatomical phenotyping of mouse embryos using micro-CT.

Development 2014 Jun 21;141(12):2533-41. Epub 2014 May 21.

Mouse Imaging Centre, Hospital for Sick Children, Toronto, Ontario M5T 3H7, Canada Department of Medical Biophysics, University of Toronto, Toronto, Ontario M5G 1L7, Canada.

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http://dx.doi.org/10.1242/dev.107722DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4050698PMC
June 2014

Cortical thickness in children receiving intensive therapy for idiopathic apraxia of speech.

Brain Topogr 2014 Mar 24;27(2):240-7. Epub 2013 Aug 24.

Division of Neurology, Pediatric Neuroimaging Research Consortium (PNRC), Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.

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http://dx.doi.org/10.1007/s10548-013-0308-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3921462PMC
March 2014

Genetic effects on cerebellar structure across mouse models of autism using a magnetic resonance imaging atlas.

Autism Res 2014 Feb 22;7(1):124-37. Epub 2013 Oct 22.

Mouse Imaging Centre, Hospital for Sick Children, Toronto, Ontario, Canada; Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/aur.1344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4418792PMC
February 2014

A perfusion procedure for imaging of the mouse cerebral vasculature by X-ray micro-CT.

J Neurosci Methods 2014 Jan 19;221:70-7. Epub 2013 Sep 19.

Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada M5G 2M9; Mouse Imaging Centre, The Hospital for Sick Children, 25 Orde Street, Toronto, Ontario, Canada M5T 3H7. Electronic address:

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http://dx.doi.org/10.1016/j.jneumeth.2013.09.002DOI Listing
January 2014

Longitudinal four-dimensional mapping of subcortical anatomy in human development.

Proc Natl Acad Sci U S A 2014 Jan 13;111(4):1592-7. Epub 2014 Jan 13.

Child Psychiatry Branch, National Institute of Mental Health, Bethesda, MD 20892.

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http://dx.doi.org/10.1073/pnas.1316911111DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3910572PMC
January 2014

Cortical morphology in children with alcohol-related neurodevelopmental disorder.

Brain Behav 2014 Jan 27;4(1):41-50. Epub 2013 Nov 27.

Neurosciences and Mental Health Research Program, The Hospital for Sick Children Toronto, Ontario, Canada ; Faculty of Medicine, University of Toronto Toronto, Ontario, Canada.

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http://doi.wiley.com/10.1002/brb3.191
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http://dx.doi.org/10.1002/brb3.191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3937705PMC
January 2014

Simulating real world functioning in schizophrenia using a naturalistic city environment and single-trial, goal-directed navigation.

Front Behav Neurosci 2013 26;7:180. Epub 2013 Nov 26.

Institute of Medical Science, University of Toronto ON, Canada ; Centre for Addiction and Mental Health, Campbell Family Mental Health Research Institute Toronto, ON, Canada.

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http://dx.doi.org/10.3389/fnbeh.2013.00180DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3840323PMC
December 2013

Impaired structural correlates of memory in Alzheimer's disease mice.

Neuroimage Clin 2013 6;3:290-300. Epub 2013 Sep 6.

Laboratory of Cerebrovascular Research, Montreal Neurological Institute, McGill University, Montréal, QC H3A 2B4, Canada.

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http://dx.doi.org/10.1016/j.nicl.2013.08.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3814975PMC
November 2013