Jason L Hornick

Jason L Hornick

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Jason L Hornick

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Characterization of molecular signatures of supratentorial ependymomas.

Mod Pathol 2019 Aug 2. Epub 2019 Aug 2.

Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1038/s41379-019-0329-2DOI Listing
August 2019

Loss of microfibril-associated protein 5 (MFAP5) expression in colon cancer stroma.

Virchows Arch 2019 Aug 18. Epub 2019 Aug 18.

Department of Pathology, University of Chicago Medical Center, Chicago, IL, USA.

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http://dx.doi.org/10.1007/s00428-019-02649-yDOI Listing
August 2019

Immunohistochemistry with a pan-TRK antibody distinguishes secretory carcinoma of the salivary gland from acinic cell carcinoma.

Histopathology 2019 Jul 16;75(1):54-62. Epub 2019 May 16.

Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1111/his.13845DOI Listing
July 2019

Identification of diverse activating mutations of the RAS-MAPK pathway in histiocytic sarcoma.

Mod Pathol 2019 Jun 9;32(6):830-843. Epub 2019 Jan 9.

Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA.

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http://www.nature.com/articles/s41379-018-0200-x
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http://dx.doi.org/10.1038/s41379-018-0200-xDOI Listing
June 2019

Detection of ERBB2 Amplification by Next-Generation Sequencing Predicts HER2 Expression in Colorectal Carcinoma.

Am J Clin Pathol 2019 Jun;152(1):97-108

Department of Pathology, Brigham and Women's Hospital, Boston, MA.

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http://dx.doi.org/10.1093/ajcp/aqz031DOI Listing
June 2019

Clinicopathologic Features of Mismatch Repair-Deficient Anaplastic Thyroid Carcinomas.

Thyroid 2019 May 16;29(5):666-673. Epub 2019 Apr 16.

1 Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1089/thy.2018.0716DOI Listing
May 2019

Beyond "Triton": Malignant Peripheral Nerve Sheath Tumors With Complete Heterologous Rhabdomyoblastic Differentiation Mimicking Spindle Cell Rhabdomyosarcoma.

Am J Surg Pathol 2019 May 17. Epub 2019 May 17.

Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1097/PAS.0000000000001290DOI Listing
May 2019

Immunohistochemical correlates of recurrent genetic alterations in sarcomas.

Genes Chromosomes Cancer 2019 02 19;58(2):111-123. Epub 2018 Dec 19.

Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts.

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http://doi.wiley.com/10.1002/gcc.22700
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http://dx.doi.org/10.1002/gcc.22700DOI Listing
February 2019

ALK Expression in Angiomatoid Fibrous Histiocytoma: A Potential Diagnostic Pitfall.

Am J Surg Pathol 2019 Jan;43(1):93-101

Department of Pathology, Robert J. Tomsich Institute of Pathology and Laboratory Medicine.

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http://dx.doi.org/10.1097/PAS.0000000000001103DOI Listing
January 2019

PAX7 expression in sarcomas bearing the EWSR1-NFATC2 translocation.

Mod Pathol 2019 01 9;32(1):154-156. Epub 2018 Jul 9.

Department of Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1038/s41379-018-0095-6DOI Listing
January 2019

Limited biopsies of soft tissue tumors: the contemporary role of immunohistochemistry and molecular diagnostics.

Authors:
Jason L Hornick

Mod Pathol 2019 Jan 2. Epub 2019 Jan 2.

Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States.

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http://dx.doi.org/10.1038/s41379-018-0139-yDOI Listing
January 2019

Expanding the spectrum of pediatric NTRK-rearranged fibroblastic tumors to the central nervous system: A case report with RBPMS-NTRK3 fusion.

Neuropathology 2018 Dec 6;38(6):624-630. Epub 2018 Sep 6.

Department of Pathology, Boston Children's Hospital and Harvard Medical School, Boston, Massachusetts, USA.

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http://doi.wiley.com/10.1111/neup.12513
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http://dx.doi.org/10.1111/neup.12513DOI Listing
December 2018

Subclassification of pleomorphic sarcomas: How and why should we care?

Authors:
Jason L Hornick

Ann Diagn Pathol 2018 Dec 11;37:118-124. Epub 2018 Oct 11.

Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10929134183032
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http://dx.doi.org/10.1016/j.anndiagpath.2018.10.006DOI Listing
December 2018

Clinical characteristics and treatment outcomes in six cases of malignant tenosynovial giant cell tumor: initial experience of molecularly targeted therapy.

BMC Cancer 2018 Dec 29;18(1):1296. Epub 2018 Dec 29.

Ludwig Center at Dana-Farber/Harvard and Center for Sarcoma and Bone Oncology, Department of Medical Oncology, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1186/s12885-018-5188-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6311045PMC
December 2018

Diagnostic Immunohistochemistry for Soft Tissue and Bone Tumors: An Update.

Adv Anat Pathol 2018 Nov;25(6):400-412

Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1097/PAP.0000000000000204DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442933PMC
November 2018

Immunohistochemistry in Surgical Pathology.

Adv Anat Pathol 2018 11;25(6):373

Brigham and Women's Hospital, Boston, MA.

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http://dx.doi.org/10.1097/PAP.0000000000000212DOI Listing
November 2018

NKX2.2 immunohistochemistry in the distinction of Ewing sarcoma from cytomorphologic mimics: Diagnostic utility and pitfalls.

Cancer Cytopathol 2018 11 30;126(11):942-949. Epub 2018 Oct 30.

Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1002/cncy.22056DOI Listing
November 2018

Imaging of Histiocytosis in the Era of Genomic Medicine.

Radiographics 2019 Jan-Feb;39(1):95-114. Epub 2018 Nov 30.

From the Departments of Radiology (H.P., M.N.), Pathology (J.L.H.), and Medical Oncology (E.D.J.), Brigham and Women's Hospital and Dana-Farber Cancer Institute, 450 Brookline Ave, Boston, MA 02215.

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http://pubs.rsna.org/doi/10.1148/rg.2019180054
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http://dx.doi.org/10.1148/rg.2019180054DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357950PMC
November 2018

Expression of PAX3 Distinguishes Biphenotypic Sinonasal Sarcoma From Histologic Mimics.

Am J Surg Pathol 2018 10;42(10):1275-1285

Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1097/PAS.0000000000001092DOI Listing
October 2018

Evaluation of pan-TRK immunohistochemistry in infantile fibrosarcoma, lipofibromatosis-like neural tumour and histological mimics.

Histopathology 2018 Oct 5;73(4):634-644. Epub 2018 Jul 5.

Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

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http://doi.wiley.com/10.1111/his.13666
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http://dx.doi.org/10.1111/his.13666DOI Listing
October 2018

MyD88 signaling in T regulatory cells by endogenous ligands dampens skin inflammation in filaggrin deficient mice.

Clin Immunol 2018 10 9;195:88-92. Epub 2018 Aug 9.

Division of Immunology, Boston Children's Hospital, Boston, MA, United States. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S15216616183047
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http://dx.doi.org/10.1016/j.clim.2018.08.001DOI Listing
October 2018

Dermatofibrosarcoma protuberans with a novel COL6A3-PDGFD fusion gene and apparent predilection for breast.

Genes Chromosomes Cancer 2018 09 14;57(9):437-445. Epub 2018 Aug 14.

Department of Pathology, Memorial Sloan Kettering Cancer Center, New York, New York.

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http://dx.doi.org/10.1002/gcc.22663DOI Listing
September 2018

Detection of Mutations in Barrett's Esophagus Before Progression to High-Grade Dysplasia or Adenocarcinoma.

Gastroenterology 2018 07 31;155(1):156-167. Epub 2018 Mar 31.

Eli and Edythe L. Broad Institute, Cambridge, Massachusetts; Department of Molecular Oncology, Dana Farber Cancer Institute, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1053/j.gastro.2018.03.047DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035092PMC
July 2018

Immunohistochemical Biomarkers of Mesenchymal Neoplasms in Endocrine Organs: Diagnostic Pitfalls and Recent Discoveries.

Endocr Pathol 2018 Jun;29(2):189-198

Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, 75 Francis Street, Boston, MA, 02115, USA.

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http://dx.doi.org/10.1007/s12022-018-9513-zDOI Listing
June 2018

The SS18-SSX Fusion Oncoprotein Hijacks BAF Complex Targeting and Function to Drive Synovial Sarcoma.

Cancer Cell 2018 06 31;33(6):1128-1141.e7. Epub 2018 May 31.

Department of Pediatric Oncology, Dana-Farber Cancer Institute and Harvard Medical School, 450 Brookline Avenue, Boston, MA 02215, USA; Epigenomics Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ccell.2018.05.002DOI Listing
June 2018

Next generation immunohistochemistry: Emerging substitutes to genetic testing?

Semin Diagn Pathol 2018 May 27;35(3):161-169. Epub 2017 Jun 27.

Department of Pathology, Brigham and Women's Hospital & Harvard Medical School, 75 Francis Street, Boston, MA 02115, USA.

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http://dx.doi.org/10.1053/j.semdp.2017.05.004DOI Listing
May 2018

Epithelioid fibrous histiocytoma: molecular characterization of ALK fusion partners in 23 cases.

Mod Pathol 2018 05 12;31(5):753-762. Epub 2018 Jan 12.

Department of Pathology, Brigham and Women's Hospital, Boston, MA, USA.

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http://www.nature.com/doifinder/10.1038/modpathol.2017.191
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http://dx.doi.org/10.1038/modpathol.2017.191DOI Listing
May 2018

Expression of enhancer of zeste homolog 2 (EZH2) protein in histiocytic and dendritic cell neoplasms with evidence for p-ERK1/2-related, but not MYC- or p-STAT3-related cell signaling.

Mod Pathol 2018 04 12;31(4):553-561. Epub 2018 Jan 12.

Brigham and Women's Hospital and Harvard Medical School, Department of Pathology, Boston, MA, USA.

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http://dx.doi.org/10.1038/modpathol.2017.174DOI Listing
April 2018

Pilot study of serial FLT and FDG-PET/CT imaging to monitor response to neoadjuvant chemoradiotherapy of esophageal adenocarcinoma: correlation with histopathologic response.

Ann Nucl Med 2018 Apr 13;32(3):165-174. Epub 2018 Jan 13.

Department of Radiation Oncology, Brigham and Women's Hospital, Harvard Medical School, Boston, USA.

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http://dx.doi.org/10.1007/s12149-018-1229-0DOI Listing
April 2018

The role of metabolic enzymes in mesenchymal tumors and tumor syndromes: genetics, pathology, and molecular mechanisms.

Lab Invest 2018 04 16;98(4):414-426. Epub 2018 Jan 16.

Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1038/s41374-017-0003-6DOI Listing
April 2018

Melanocytic naevi with perineurial differentiation: a distinctive variant of neurotised naevi and a diagnostic pitfall with desmoplastic melanoma.

Histopathology 2018 Mar 14;72(4):679-684. Epub 2017 Dec 14.

Department of Pathology, Western General Hospital and The University of Edinburgh, Edinburgh, UK.

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http://dx.doi.org/10.1111/his.13418DOI Listing
March 2018

SOX10/keratin dual-color immunohistochemistry: An effective first-line test for the workup of epithelioid malignant neoplasms in FNA and small biopsy specimens.

Cancer Cytopathol 2018 03 31;126(3):179-189. Epub 2018 Jan 31.

Department of Pathology, Brigham and Women's Hospital, and Harvard Medical School, Boston, Massachusetts.

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http://dx.doi.org/10.1002/cncy.21960DOI Listing
March 2018

Contemporary Sarcoma Diagnosis, Genetics, and Genomics.

J Clin Oncol 2018 01 8;36(2):101-110. Epub 2017 Dec 8.

Inga-Marie Schaefer and Jason L. Hornick, Brigham and Women's Hospital-Harvard Medical School; and Gregory M. Cote, Massachusetts General Hospital Cancer Center-Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1200/JCO.2017.74.9374DOI Listing
January 2018

Differences in the imaging features and distribution of non-indolent and indolent mastocytosis: a single institution experience of 29 patients.

Clin Imaging 2017 Jul - Aug;44:111-116. Epub 2017 May 6.

Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, 75 Francis Street, Boston, MA 02115, United States; Department of Imaging, Dana Farber Cancer Institute, Harvard Medical School, 450 Brookline Avenue, Boston, MA 02215, United States.

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http://dx.doi.org/10.1016/j.clinimag.2017.05.003DOI Listing
December 2017

PHOX2B reliably distinguishes neuroblastoma among small round blue cell tumours.

Histopathology 2017 Nov 6;71(5):786-794. Epub 2017 Sep 6.

Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1111/his.13288DOI Listing
November 2017

Correspondence.

Am J Clin Pathol 2017 11;148(5):462-463

Department of Pathology Brigham and Women's HospitalBoston, MA.

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http://dx.doi.org/10.1093/ajcp/aqx113DOI Listing
November 2017

Examination of PHOX2B in adult neuroendocrine neoplasms reveals relatively frequent expression in phaeochromocytomas and paragangliomas.

Histopathology 2017 Oct 13;71(4):503-510. Epub 2017 Jul 13.

Department of Pathology, University of Iowa Hospitals and Clinics and Carver College of Medicine, Iowa City, IA, USA.

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http://doi.wiley.com/10.1111/his.13243
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http://dx.doi.org/10.1111/his.13243DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5597462PMC
October 2017

Cyclin D1 Is Expressed in Neoplastic Cells of Langerhans Cell Histiocytosis but Not Reactive Langerhans Cell Proliferations.

Am J Surg Pathol 2017 Oct;41(10):1390-1396

Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1097/PAS.0000000000000897DOI Listing
October 2017

The Utility of Immunohistochemistry in Mycobacterial Infection: A Proposal for Multimodality Testing.

Am J Surg Pathol 2017 Oct;41(10):1364-1370

*Department of Pathology, Brigham and Women's Hospital, Boston, MA †American Society for Clinical Pathology, Chicago, IL.

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http://dx.doi.org/10.1097/PAS.0000000000000925DOI Listing
October 2017

Somatic mutations in and in primary carcinomas at 13 anatomic sites.

Oncotarget 2017 Oct 21;8(49):85680-85691. Epub 2017 Sep 21.

Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.

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http://www.oncotarget.com/fulltext/21115
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http://dx.doi.org/10.18632/oncotarget.21115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5689640PMC
October 2017

Current Concepts in the Molecular Genetics and Management of Thyroid Cancer: An Update for Radiologists.

Radiographics 2016 Sep-Oct;36(5):1478-93

From the Departments of Radiology (T.K., A.R.K., S.A.H., K.M.K., M.B.A., N.H.R., S.H.T.) and Pathology (J.L.H.), Brigham and Women's Hospital, Harvard Medical School, 75 Francis St, Boston, MA 02115; and Department of Imaging, Dana Farber Cancer Institute, Harvard Medical School, Boston, Mass (A.R.K., S.A.H., K.M.K., M.B.A., N.H.R., S.H.T.).

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http://dx.doi.org/10.1148/rg.2016150206DOI Listing
September 2017

EWSR1 fusion proteins mediate PAX7 expression in Ewing sarcoma.

Mod Pathol 2017 09 23;30(9):1312-1320. Epub 2017 Jun 23.

Departments of Pathology &Translational Molecular Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

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http://dx.doi.org/10.1038/modpathol.2017.49DOI Listing
September 2017

Role of Histone H3K27 Trimethylation Loss as a Marker for Malignant Peripheral Nerve Sheath Tumor in Fine-Needle Aspiration and Small Biopsy Specimens.

Am J Clin Pathol 2017 Aug;148(2):179-189

Department of Pathology, Brigham and Women's Hospital, Boston, MA.

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http://dx.doi.org/10.1093/ajcp/aqx060DOI Listing
August 2017

Phosphatidylcholine transfer protein/StarD2 promotes microvesicular steatosis and liver injury in murine experimental steatohepatitis.

Am J Physiol Gastrointest Liver Physiol 2017 Jul 6;313(1):G50-G61. Epub 2017 Apr 6.

Department of Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts; and

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http://dx.doi.org/10.1152/ajpgi.00379.2016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5538832PMC
July 2017

Morphological Features and Prognostic Significance of ARID1A-Deficient Esophageal Adenocarcinomas.

Arch Pathol Lab Med 2017 Jul 25;141(7):970-977. Epub 2017 Apr 25.

From the Departments of Pathology (Drs Drage, Tippayawong, Agoston, Hornick, Odze, and Srivastava) and Surgery (Drs Zheng and Bueno), Brigham and Women's Hospital, Boston, Massachusetts. Dr Drage is now with the Department of Pathology, University of Rochester Medical Center, Rochester, New York.

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http://dx.doi.org/10.5858/arpa.2016-0318-OADOI Listing
July 2017

Abnormal p53 and p16 staining patterns distinguish uterine leiomyosarcoma from inflammatory myofibroblastic tumour.

Histopathology 2017 Jun 20;70(7):1138-1146. Epub 2017 Mar 20.

Department of Pathology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1111/his.13176DOI Listing
June 2017

Histologic Appearance After Preoperative Radiation Therapy for Soft Tissue Sarcoma: Assessment of the European Organization for Research and Treatment of Cancer-Soft Tissue and Bone Sarcoma Group Response Score.

Int J Radiat Oncol Biol Phys 2017 06 24;98(2):375-383. Epub 2017 Feb 24.

Center for Sarcoma and Bone Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts; Department of Radiation Oncology, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts. Electronic address:

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http://dx.doi.org/10.1016/j.ijrobp.2017.02.087DOI Listing
June 2017

FOSB is a Useful Diagnostic Marker for Pseudomyogenic Hemangioendothelioma.

Am J Surg Pathol 2017 May;41(5):596-606

Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1097/PAS.0000000000000795DOI Listing
May 2017

Recurrent IDH2 R172X mutations in sinonasal undifferentiated carcinoma.

Mod Pathol 2017 05 13;30(5):650-659. Epub 2017 Jan 13.

Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1038/modpathol.2016.239DOI Listing
May 2017

Evolution of Quality Assurance for Clinical Immunohistochemistry in the Era of Precision Medicine: Part 4: Tissue Tools for Quality Assurance in Immunohistochemistry.

Appl Immunohistochem Mol Morphol 2017 04;25(4):227-230

*Department of Laboratory Medicine and Pathobiology, University of Toronto Departments of †Pathology §§§§Laboratory Hematology, University Health Network, Toronto, ON §§Vancouver General Hospital, University of British Columbia, Vancouver, BC ###Department of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB ∥∥∥∥Canadian Immunohistochemistry Quality Control (CIQC)/Canadian Association of Pathologists National Standards Committee for High Complexity Testing/Immunohistochemistry, Canada ‡Poundbury Cancer Institute §Dorset County Hospital NHS Foundation Trust ∥Cancer Diagnostic Quality Assurance Services (CADQAScic), Dorchester ¶¶Department of Surgery & Cancer, Division of Cancer, Imperial College London ***UK National External Quality Assessment Scheme (UK NEQAS), University College London, London, UK ∥∥International Quality Network for Pathology (IQN Path), Luxembourg City, Luxembourg ¶School of Medicine, Institute of Pathology, Charité-University Hospital Berlin, Berlin, Germany #Griffith University, Gold Coast ††Genomics For Life, Brisbane, Qld **RCPA Quality Assurance Program, Sydney, NSW, Australia ‡‡Phenopath, Seattle, WA ##Brigham and Women's Hospital, Harvard Medical School, Boston, MA ****Keck School of Medicine, University of Southern California, Los Angeles, CA †††Center of Predictive Molecular Medicine ‡‡‡Center for Excellence on Ageing and Translational Medicine, University of Chieti-Pescara, Chieti, Italy §§§Department of Pathology, Radboud University Medical Centre, Nijmegen, The Netherlands ∥∥∥Institute of Pathology, Aalborg University Hospital and Department of Clinical Medicine, Aalborg University ¶¶¶Nordic Immunohistochemistry Quality Control (NordiQC), Aalborg, Denmark ††††Department of Pathology, Beijing Friendship Hospital, Capital Medical University, Beijing ‡‡‡‡Chinese Committee for Pathologists-Immunohistochemistry Quality Control, China.

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http://dx.doi.org/10.1097/PAI.0000000000000469DOI Listing
April 2017

Claudin-4 expression distinguishes SWI/SNF complex-deficient undifferentiated carcinomas from sarcomas.

Mod Pathol 2017 04 13;30(4):539-548. Epub 2017 Jan 13.

Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1038/modpathol.2016.230DOI Listing
April 2017

Cancer Susceptibility Gene Mutations in Individuals With Colorectal Cancer.

J Clin Oncol 2017 Apr 30;35(10):1086-1095. Epub 2017 Jan 30.

Matthew B. Yurgelun, Matthew H. Kulke, Charles S. Fuchs, Hajime Uno, Chinedu I. Ukaegbu, Lauren K. Brais, Philip G. McNamara, Robert J. Mayer, Deborah Schrag, Jeffrey A. Meyerhardt, Kimmie Ng, and Sapna Syngal, Dana-Farber Cancer Institute; Matthew B. Yurgelun, Matthew H. Kulke, Charles S. Fuchs, Hajime Uno, Jason L. Hornick, Robert J. Mayer, Deborah Schrag, Jeffrey A. Meyerhardt, Kimmie Ng, and Sapna Syngal, Harvard Medical School; Matthew B. Yurgelun, Matthew H. Kulke, Charles S. Fuchs, Jason L. Hornick, Robert J. Mayer, Deborah Schrag, Jeffrey A. Meyerhardt, Kimmie Ng, and Sapna Syngal, Brigham and Women's Hospital, Boston, MA; and Brian A. Allen, John Kidd, Nanda Singh, Anne-Renee Hartman, and Richard J. Wenstrup, Myriad Genetics, Salt Lake City, UT.

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http://dx.doi.org/10.1200/JCO.2016.71.0012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5455355PMC
April 2017

Frequent low-level mutations of protein kinase D2 in angiolipoma.

J Pathol 2017 04 27;241(5):578-582. Epub 2017 Feb 27.

Division of Clinical Genetics, Department of Laboratory Medicine, Lund University, 221 84, Lund, Sweden.

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http://dx.doi.org/10.1002/path.4865DOI Listing
April 2017

Role of Imaging in Management of Desmoid-type Fibromatosis: A Primer for Radiologists.

Radiographics 2016 May-Jun;36(3):767-82

From the Department of Imaging, Dana-Farber Cancer Institute, Harvard Medical School, 450 Brookline Ave, Boston, MA 02215 (M.B.A., A.R.K., K.M.K., S.H.T., A.B.S., N.H.R., J.P.J.); Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (M.B.A., A.R.K., K.M.K., S.H.T., A.B.S., N.H.R., J.P.J.); Department of Pathology, Brigham and Women's Hospital and Dana-Farber Cancer Institute, Harvard Medical School, Boston, Mass (J.L.H.); Department of Radiation Oncology, Brigham and Women's Hospital and Dana-Farber Cancer Institute, Harvard Medical School, Boston, Mass (E.H.B.); and Center for Sarcoma and Bone Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Mass (S.G.).

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http://dx.doi.org/10.1148/rg.2016150153DOI Listing
March 2017

Universal Screening for Mismatch-Repair Deficiency in Endometrial Cancers to Identify Patients With Lynch Syndrome and Lynch-like Syndrome.

Int J Gynecol Pathol 2017 Mar;36(2):115-127

Departments of Pathology (J.C.W., J.L.H., C.P.C, L.M.S., B.E.H.) Gynecologic Oncology (M.C.M., C.M.F., R.S.B., N.S.H.), Brigham And Women's Hospital Department of Medical Oncology (S.S., M.B.Y., A.C.), Dana-Farber Cancer Institute, Boston, MA Department of Pathology (E.J.Y.), Stanford University Medical Center, Palo Alto, CA.

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http://dx.doi.org/10.1097/PGP.0000000000000312DOI Listing
March 2017

Evolution of Quality Assurance for Clinical Immunohistochemistry in the Era of Precision Medicine. Part 3: Technical Validation of Immunohistochemistry (IHC) Assays in Clinical IHC Laboratories.

Appl Immunohistochem Mol Morphol 2017 03;25(3):151-159

*Department of Laboratory Medicine and Pathobiology, University of Toronto Departments of †Laboratory Hematology §Pathology, University Health Network, Toronto, ON ∥∥Vancouver General Hospital, University of British Columbia, Vancouver, BC ¶¶¶Department of Pathology and Laboratory Medicine, Cumming School of Medicine University of Calgary, and Calgary Laboratory Services, Calgary, AB, Canada ‡Canadian Immunohistochemistry Quality Control (CIQC), Vancouver, BC, Canada/Canadian Association of Pathologists National Standards Committee for High Complexity Testing/Immunohistochemistry ∥Poundbury Cancer Institute ¶Dorset County Hospital NHS Foundation Trust, Dorchester, UK #Cancer Diagnostic Quality Assurance Services (CADQAScic), Dorchester ***UK National External Quality Assessment Scheme (UK NEQAS), University College London, London, UK **School of Medicine, Institute of Pathology, Charité-University Hospital, Berlin, Berlin, Germany ††Griffith University, Gold Coast ‡‡RCPA Quality Assurance Program, Sydney §§Genomics For Life, Brisbane, Australia ¶¶International Quality Network for Pathology (IQN Path), Luxembourg City, Luxembourg ##Brigham and Women's Hospital, Harvard Medical School, Boston, MA †††Center of Predictive Molecular Medicine, Center for Excellence on Ageing and Translational Medicine, University of Chieti-Pescara, Chieti, Italy ‡‡‡Department of Pathology, Radboud University Medical Centre, Nijmegen, The Netherlands §§§Institute of Pathology, and Department of Clinical Medicine, Aalborg University, Aalborg University Hospital ∥∥∥Nordic Immunohistochemistry Quality Control (NordiQC), Aalborg, Denmark ###Department of Pathology, Beijing Friendship Hospital, Capital Medical University, Beijing ****Chinese Committee for Pathologists-Immunohistochemistry Quality Control, China ††††Keck School of Medicine, University of Southern California, Los Angeles, CA.

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http://dx.doi.org/10.1097/PAI.0000000000000470DOI Listing
March 2017

Evolution of Quality Assurance for Clinical Immunohistochemistry in the Era of Precision Medicine - Part 2: Immunohistochemistry Test Performance Characteristics.

Appl Immunohistochem Mol Morphol 2017 02;25(2):79-85

*Department of Laboratory Medicine and Pathobiology, University of Toronto, Vancouver, BC, CanadaDepartment of †Laboratory Hematology§Pathology, University Health Network, Toronto, ON, Canada‡Canadian Immunohistochemistry Quality Control (CIQC)/Canadian Association of Pathologists National Standards Committee for High Complexit Testing/Immunohistochemistry∥Poundbury Cancer Institute¶Dorset County Hospital NHS Foundation Trust#Cancer Diagnostic Quality Assurance Services (CADQAScic), Dorchester, UK***UK National External Quality Assessment Scheme (UK NEQAS), University College London, London, UK**"Rudolf-Virchow-Haus", Institute of Pathology, Charité-University Hospital Berlin, Berlin, Germany††School of Medicine, Griffith University, Gold Coast‡‡Genomics For Life, Brisbane, QLD§§RCPA Quality Assurance Program, Sydney, NSW, Australia∥∥Vancouver General Hospital, University of British Columbia, Vancouver, BC, Canada¶¶International Quality Network for Pathology (IQN Path), Luxembourg City, Luxembourg, and Division of Cancer, Department of Surgery & Cancer, Imperial College London, UK##Brigham and Women's Hospital, Harvard Medical School, Boston, MA†††Center of Predictive Molecular Medicine, Center for Excellence on Ageing and Translational Medicine, University of Chieti-Pescara, Chieti, Italy‡‡‡Department of Pathology, Radboud University Medical Centre, Nijmegen, The Netherlands§§§Institute of Pathology, Aalborg University Hospital and Department of Clinical Medicine, Aalborg University, Denmark∥∥∥Nordic Immunohistochemistry Quality Control (NordiQC), Aalborg, Denmark¶¶¶Department of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary and Calgary Laboratory Services, Calgary, AB###Department of Pathology, Beijing Friendship Hospital, Capital Medical University****CCP-IHCQC, Chinese Committee for Pathologists-Immunohistochemistry Quality Control, Beijing, China††††Keck School of Medicine, University of Southern California, Los Angeles, CA.

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http://dx.doi.org/10.1097/PAI.0000000000000444DOI Listing
February 2017

Primary Extremity Liposarcoma: MRI Features, Histopathology, and Clinical Outcomes.

J Comput Assist Tomogr 2016 Sep-Oct;40(5):791-8

From the *Department of Radiology, Brigham and Women's Hospital, †Department of Imaging, Dana Farber Cancer Institute, and ‡Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1097/RCT.0000000000000431DOI Listing
January 2017

Metastatic Patterns of Solitary Fibrous Tumors: A Single-Institution Experience.

AJR Am J Roentgenol 2017 Jan 20;208(1):2-9. Epub 2016 Oct 20.

1 Department of Imaging, Dana Farber Cancer Institute, 450 Brookline Ave, Boston, MA 02115.

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http://dx.doi.org/10.2214/AJR.16.16662DOI Listing
January 2017

Evolution of Quality Assurance for Clinical Immunohistochemistry in the Era of Precision Medicine: Part 1: Fit-for-Purpose Approach to Classification of Clinical Immunohistochemistry Biomarkers.

Appl Immunohistochem Mol Morphol 2017 01;25(1):4-11

*Department of Laboratory Medicine and Pathobiology, University of Toronto †Department of Pathology, University Health Network ††††Department of Laboratory Hematology, University Health Network, Toronto, ON ‡‡Vancouver General Hospital, University of British Columbia, Vancouver, BC ∥∥∥Department of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary, Calgary, AB, Canada ‡Poundbury Cancer Institute §Dorset County Hospital NHS Foundation Trust ∥Cancer Diagnostic Quality Assurance Services (CADQAScic), Dorchester ∥∥Division of Cancer, Department of Surgery & Cancer, Imperial College, London, UK ##UK National External Quality Assessment Scheme (UK NEQAS), University College London, London, UK ¶School of Medicine, Institute of Pathology, Charité-University Hospital Berlin, Berlin, Germany #Griffith University, Gold Coast **RCPA Quality Assurance Program, Sydney ††Genomics For Life, Brisbane, Australia §§International Quality Network for Pathology (IQN Path), Luxembourg City, Luxembourg ¶¶Brigham and Women's Hospital, Harvard Medical School, Boston, MA ***Center of Predictive Molecular Medicine, Center for Excellence on Ageing and Translational Medicine, University of Chieti-Pescara, Chieti, Italy †††Department of Pathology, Radboud University Medical Centre, Nijmegen, The Netherlands ‡‡‡Institute of Pathology, Aalborg University Hospital and Department of Clinical Medicine, Aalborg University §§§Nordic Immunohistochemistry Quality Control (NordiQC), Aalborg, Denmark ¶¶¶Keck School of Medicine, University of Southern California, Los Angeles, CA ###Department of Pathology, Beijing Friendship Hospital, Capital Medical University, Beijing, China ****Chinese Committee for Pathologists-Immunohistochemistry Quality Control ‡‡‡‡Canadian Immunohistochemistry Quality Control (CIQC)/Canadian Association of Pathologists National Standards Committee for High Complexity Testing/Immunohistochemistry, Vancouver, BC, Canada.

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http://dx.doi.org/10.1097/PAI.0000000000000451DOI Listing
January 2017

Radiation-associated neoplasia: clinical, pathological and genomic correlates.

Histopathology 2017 Jan;70(1):70-80

Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1111/his.13069DOI Listing
January 2017

Immunohistochemistry Is Rarely Justified for the Diagnosis of Viral Infections.

Am J Clin Pathol 2017 Jan;147(1):96-104

From the Department of Pathology, Brigham and Women's Hospital, Boston, MA.

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http://dx.doi.org/10.1093/ajcp/aqw198DOI Listing
January 2017

Conventional Risk Stratification Fails to Predict Progression of Succinate Dehydrogenase-deficient Gastrointestinal Stromal Tumors: A Clinicopathologic Study of 76 Cases.

Am J Surg Pathol 2016 12;40(12):1616-1621

Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

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http://dx.doi.org/10.1097/PAS.0000000000000685DOI Listing
December 2016

Evaluation of ETV4 and WT1 expression in CIC-rearranged sarcomas and histologic mimics.

Mod Pathol 2016 11 22;29(11):1324-1334. Epub 2016 Jul 22.

Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1038/modpathol.2016.140DOI Listing
November 2016

H3K27me3 immunohistochemistry highlights the inactivated X chromosome (Xi) and predicts sex in non-neoplastic tissues.

Histopathology 2016 Oct 4;69(4):702-4. Epub 2016 May 4.

Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

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http://dx.doi.org/10.1111/his.12972DOI Listing
October 2016

Endoscopic Features and Eosinophil Density Are Associated with Food Impaction in Adults with Esophageal Eosinophilia.

Dig Dis Sci 2016 09 19;61(9):2578-84. Epub 2016 May 19.

Division of Gastroenterology, Hepatology and Endoscopy, Brigham and Women's Hospital, 75 Francis Street, Boston, MA, 02115, USA.

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http://dx.doi.org/10.1007/s10620-016-4190-6DOI Listing
September 2016

Molecular Evaluation of Colorectal Adenocarcinoma: Current Practice and Emerging Concepts.

Surg Pathol Clin 2016 Sep;9(3):427-39

Department of Pathology, Brigham and Women's Hospital, 75 Francis Street, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.path.2016.04.007DOI Listing
September 2016

Somatic mutations in histiocytic sarcoma identified by next generation sequencing.

Virchows Arch 2016 Aug 3;469(2):233-41. Epub 2016 Jun 3.

Department of Pathology, UMass Memorial Medical Center and University of Massachusetts Medical School, Worcester, MA, USA.

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http://dx.doi.org/10.1007/s00428-016-1965-2DOI Listing
August 2016

Autoimmune Pancreatitis Presenting as Multifocal Masses, Diagnosed on Ampullary Biopsy.

Pancreas 2016 07;45(6):e25-7

Division of Gastroenterology, Hepatology and Endoscopy Brigham and Women's Hospital Boston, MA Department of Pathology Brigham and Women's Hospital Boston, MA Department of Radiology Brigham and Women's Hospital Boston, MA Department of Surgery Brigham and Women's Hospital Boston, MA Division of Gastroenterology, Hepatology and Endoscopy Brigham and Women's Hospital Boston, MA.

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http://dx.doi.org/10.1097/MPA.0000000000000581DOI Listing
July 2016

Ipilimumab for Patients with Relapse after Allogeneic Transplantation.

N Engl J Med 2016 Jul;375(2):143-53

From the Department of Medical Oncology, Dana-Farber Cancer Institute and Harvard Medical School (M.S.D., H.T.K., P.B., R.L., A.S., A.P.L., M.H., M.S., F.S.H., C.J.W., V.T.H., C. Cutler, J.K., E.P.A., J.H.A., P.A., J.R., R.J.S.), the Bone Marrow Transplant Program, Beth Israel Deaconess Medical Center and Harvard Medical School (D.A.), the Bone Marrow Transplant Program, Massachusetts General Hospital Cancer Center and Harvard Medical School (Y.-B.C.), the Departments of Dermatology (N.R.L.) and Pathology (S.R.G., J.L.H., S.J.R.), Dana-Farber and Brigham and Women's Cancer Center, and the Dana-Farber Cancer Institute, Center for Molecular Oncologic Pathology (M.B., C.W.Z.) - all in Boston; Broad Institute of Massachusetts Institute of Technology and Harvard (P.B., C.J.W.) and Neon Therapeutics (M.S.R.) - both in Cambridge; the Blood and Marrow Transplant Program, University of California, San Diego, Moores Cancer Center, La Jolla (C. Costello, E.D.B.); Colorado Blood Cancer Institute, Denver (P.M.); Cancer Therapy Evaluation Program, National Cancer Institute, Bethesda, MD (H.S.); and the Blood and Marrow Transplant Group of Georgia at Northside Hospital, Atlanta (A.B.).

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http://dx.doi.org/10.1056/NEJMoa1601202DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5149459PMC
July 2016