Jason Gertz

Jason Gertz

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Jason Gertz

Jason Gertz

Publications by authors named "Jason Gertz"

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47Publications

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FFPEcap-seq: a method for sequencing capped RNAs in formalin-fixed paraffin-embedded samples.

Genome Res 2019 Nov 24;29(11):1826-1835. Epub 2019 Oct 24.

Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, Utah 84112, USA.

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http://dx.doi.org/10.1101/gr.249656.119DOI Listing
November 2019

Sufficiency analysis of estrogen responsive enhancers using synthetic activators.

Life Sci Alliance 2019 Oct 30;2(5). Epub 2019 Sep 30.

Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA

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http://dx.doi.org/10.26508/lsa.201900497DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6769255PMC
October 2019

Lentiviral CRISPR Epigenome Editing of Inflammatory Receptors as a Gene Therapy Strategy for Disc Degeneration.

Hum Gene Ther 2019 09 17;30(9):1161-1175. Epub 2019 Jul 17.

Department of Biomedical Engineering, University of Utah, Salt Lake City, Utah.

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http://dx.doi.org/10.1089/hum.2019.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6761595PMC
September 2019

Estrogen-independent molecular actions of mutant estrogen receptor 1 in endometrial cancer.

Genome Res 2019 09 30;29(9):1429-1441. Epub 2019 Jul 30.

Department of Oncological Sciences, University of Utah, Salt Lake City, Utah 84112, USA.

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http://dx.doi.org/10.1101/gr.244780.118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6724674PMC
September 2019

NHR-14 loss of function couples intestinal iron uptake with innate immunity in through PQM-1 signaling.

Elife 2019 09 18;8. Epub 2019 Sep 18.

Department of Medicine, Division of Hematology, University of Utah, Salt Lake City, United States.

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http://dx.doi.org/10.7554/eLife.44674DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6777940PMC
September 2019

Estrogen Signaling in Endometrial Cancer: a Key Oncogenic Pathway with Several Open Questions.

Horm Cancer 2019 06 2;10(2-3):51-63. Epub 2019 Feb 2.

Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA.

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http://dx.doi.org/10.1007/s12672-019-0358-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6542701PMC
June 2019

Dissection of Enhancer Function Using Multiplex CRISPR-based Enhancer Interference in Cell Lines.

J Vis Exp 2018 06 2(136). Epub 2018 Jun 2.

Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah;

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http://dx.doi.org/10.3791/57883DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6101477PMC
June 2018

Clinical and Genomic Crosstalk between Glucocorticoid Receptor and Estrogen Receptor α In Endometrial Cancer.

Cell Rep 2018 03;22(11):2995-3005

Department of Oncological Sciences, University of Utah, Salt Lake City, UT 84112, USA; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2018.02.076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5870123PMC
March 2018

GIGGLE: a search engine for large-scale integrated genome analysis.

Nat Methods 2018 02 8;15(2):123-126. Epub 2018 Jan 8.

Department of Human Genetics, University of Utah, Salt Lake City, Utah, USA.

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http://dx.doi.org/10.1038/nmeth.4556DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5872823PMC
February 2018

Multiplex Enhancer Interference Reveals Collaborative Control of Gene Regulation by Estrogen Receptor α-Bound Enhancers.

Cell Syst 2017 10 27;5(4):333-344.e5. Epub 2017 Sep 27.

Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah, Salt Lake City, UT 84112, USA. Electronic address:

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http://dx.doi.org/10.1016/j.cels.2017.08.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679353PMC
October 2017

CRISPR Epigenome Editing of AKAP150 in DRG Neurons Abolishes Degenerative IVD-Induced Neuronal Activation.

Mol Ther 2017 09 1;25(9):2014-2027. Epub 2017 Jul 1.

Department of Bioengineering, University of Utah, Salt Lake City, UT 84112, USA; Department of Orthopaedics, University of Utah, Salt Lake City, UT 84112, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ymthe.2017.06.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5589089PMC
September 2017

Improved survival among colon cancer patients with increased differentially expressed pathways.

BMC Med 2015 Apr 8;13:75. Epub 2015 Apr 8.

Department of Internal Medicine, University of Utah School of Medicine, 383 Colorow, Salt Lake City, 84018, USA.

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http://dx.doi.org/10.1186/s12916-015-0292-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4389992PMC
April 2015

From single-cell to cell-pool transcriptomes: stochasticity in gene expression and RNA splicing.

Genome Res 2014 Mar 3;24(3):496-510. Epub 2013 Dec 3.

Division of Biology, California Institute of Technology, Pasadena, California 91125, USA;

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http://genome.cshlp.org/cgi/doi/10.1101/gr.161034.113
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http://dx.doi.org/10.1101/gr.161034.113DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3941114PMC
March 2014

CTCF/cohesin-mediated DNA looping is required for protocadherin α promoter choice.

Proc Natl Acad Sci U S A 2012 Dec 30;109(51):21081-6. Epub 2012 Nov 30.

Key Laboratory of Systems Biomedicine, Ministry of Education, Center for Comparative Biomedicine, Institute of Systems Biomedicine, Shanghai Jiao Tong University, Shanghai 200240, China.

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http://dx.doi.org/10.1073/pnas.1219280110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3529044PMC
December 2012

Research resource: enhanced genome-wide occupancy of estrogen receptor α by the cochaperone p23 in breast cancer cells.

Mol Endocrinol 2012 Jan 10;26(1):194-202. Epub 2011 Nov 10.

Department of Pharmacology, New York University School of Medicine, New York, New York 10016, USA.

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https://academic.oup.com/mend/article-lookup/doi/10.1210/me.
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http://dx.doi.org/10.1210/me.2011-1068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248325PMC
January 2012

IκB kinase epsilon (IKK(epsilon)) regulates the balance between type I and type II interferon responses.

Proc Natl Acad Sci U S A 2011 Dec 14;108(52):21170-5. Epub 2011 Dec 14.

Department of Molecular and Cellular Biology, Harvard University, Cambridge, MA 02138, USA.

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http://dx.doi.org/10.1073/pnas.1119137109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3248534PMC
December 2011

Allele-specific distribution of RNA polymerase II on female X chromosomes.

Hum Mol Genet 2011 Oct 26;20(20):3964-73. Epub 2011 Jul 26.

Genome Biology Group, Duke Institute for Genome Sciences & Policy, Duke University, CIEMAS 2376, 101 Science Drive, Durham, 27708 NC, USA.

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http://dx.doi.org/10.1093/hmg/ddr315DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3177651PMC
October 2011

Epistasis in a quantitative trait captured by a molecular model of transcription factor interactions.

Theor Popul Biol 2010 Feb 8;77(1):1-5. Epub 2009 Oct 8.

Center for Genome Sciences, Department of Genetics, Washington University in St. Louis School of Medicine, 4444 Forest Park Blvd., St. Louis, MO 63108, United States.

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http://dx.doi.org/10.1016/j.tpb.2009.10.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2813966PMC
February 2010

Environment-specific combinatorial cis-regulation in synthetic promoters.

Mol Syst Biol 2009 17;5:244. Epub 2009 Feb 17.

Center for Genome Sciences, Department of Genetics, Washington University in St Louis School of Medicine, St Louis, MO 63108, USA.

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http://dx.doi.org/10.1038/msb.2009.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2657533PMC
April 2009

Analysis of combinatorial cis-regulation in synthetic and genomic promoters.

Nature 2009 Jan 23;457(7226):215-8. Epub 2008 Nov 23.

Center for Genome Sciences, Department of Genetics, Washington University in Saint Louis School of Medicine, 4444 Forest Park Avenue, St Louis, Missouri 63108, USA.

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http://dx.doi.org/10.1038/nature07521DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2677908PMC
January 2009

A cis-regulatory logic simulator.

BMC Bioinformatics 2007 Jul 27;8:272. Epub 2007 Jul 27.

Department of Genetics, Washington University School of Medicine, St. Louis, MO 63108, USA.

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http://dx.doi.org/10.1186/1471-2105-8-272DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2375358PMC
July 2007

Phylogeny based discovery of regulatory elements.

BMC Bioinformatics 2006 May 22;7:266. Epub 2006 May 22.

Department of Genetics, Washington University School of Medicine, 4444 Forest Park Parkway, St. Louis, MO 63108, USA.

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http://dx.doi.org/10.1186/1471-2105-7-266DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1525002PMC
May 2006

Discovery, validation, and genetic dissection of transcription factor binding sites by comparative and functional genomics.

Genome Res 2005 Aug;15(8):1145-52

Department of Genetics, Washington University School of Medicine, St. Louis, Missouri 63108, USA.

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http://dx.doi.org/10.1101/gr.3859605DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1182227PMC
August 2005

Inferring protein interactions from phylogenetic distance matrices.

Bioinformatics 2003 Nov;19(16):2039-45

Department of Mathematics, 310 Malott Hall, Cornell University, Ithaca, NY 14853-4201, USA.

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http://dx.doi.org/10.1093/bioinformatics/btg278DOI Listing
November 2003