Jason G Mezey

Jason G Mezey

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Jason G Mezey

Jason G Mezey

Publications by authors named "Jason G Mezey"

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69Publications

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Role of KRAS in regulating normal human airway basal cell differentiation.

Respir Res 2019 Aug 9;20(1):181. Epub 2019 Aug 9.

Department of Genetic Medicine, Weill Cornell Medical College, 1300 York Avenue, Box 164, New York, NY, 10065, USA.

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http://dx.doi.org/10.1186/s12931-019-1129-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6688249PMC
August 2019

Point-of-care whole-exome sequencing of idiopathic male infertility.

Genet Med 2018 11 12;20(11):1365-1373. Epub 2018 Apr 12.

Department of Genetic Medicine, Weill Cornell Medical College, New York, New York, USA.

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http://dx.doi.org/10.1038/gim.2018.10DOI Listing
November 2018

Inferring Identical-by-Descent Sharing of Sample Ancestors Promotes High-Resolution Relative Detection.

Am J Hum Genet 2018 07 21;103(1):30-44. Epub 2018 Jun 21.

Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, NY 14853, USA. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2018.05.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6035284PMC
July 2018

Benchmarking Relatedness Inference Methods with Genome-Wide Data from Thousands of Relatives.

Genetics 2017 09 24;207(1):75-82. Epub 2017 Jul 24.

Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, New York 14853

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http://dx.doi.org/10.1534/genetics.117.1122DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5586387PMC
September 2017

An independent component analysis confounding factor correction framework for identifying broad impact expression quantitative trait loci.

PLoS Comput Biol 2017 05 15;13(5):e1005537. Epub 2017 May 15.

Department of Genetic Medicine, Weill Cornell Medical College, New York, NY, United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.1005537DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5448815PMC
May 2017

Anti-hIgE gene therapy of peanut-induced anaphylaxis in a humanized murine model of peanut allergy.

J Allergy Clin Immunol 2016 12 29;138(6):1652-1662.e7. Epub 2016 Jun 29.

Department of Genetic Medicine, Weill Cornell Medical College, New York, NY. Electronic address:

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http://dx.doi.org/10.1016/j.jaci.2016.03.053DOI Listing
December 2016

Progression to COPD in smokers with normal spirometry/low DLCO using different methods to determine normal levels.

Eur Respir J 2016 06;47(6):1888-9

Dept of Genetic Medicine, Weill Cornell Medical College, NY, NY, USA Division of Pulmonary and Critical Care Medicine, Department of Medicine, Weill Cornell Medical College, NY, NY, USA

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http://dx.doi.org/10.1183/13993003.00435-2016DOI Listing
June 2016

Persistence of smoking-induced dysregulation of miRNA expression in the small airway epithelium despite smoking cessation.

PLoS One 2015 17;10(4):e0120824. Epub 2015 Apr 17.

Department of Genetic Medicine, Weill Cornell Medical College, New York, New York, United States of America; Division of Pulmonary and Critical Care Medicine, Department of Medicine, Weill Cornell Medical College, New York, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0120824PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4401720PMC
January 2016

lrgpr: interactive linear mixed model analysis of genome-wide association studies with composite hypothesis testing and regression diagnostics in R.

Bioinformatics 2014 Nov 16;30(21):3134-5. Epub 2014 Jul 16.

Department of Genetics and Genomic Sciences, Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA, Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, USA and Department of Genetic Medicine, Weill Cornell Medical College, New York, NY, USA Department of Genetics and Genomic Sciences, Icahn Institute for Genomics and Multiscale Biology, Icahn School of Medicine at Mount Sinai, New York, NY, USA, Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, USA and Department of Genetic Medicine, Weill Cornell Medical College, New York, NY, USA.

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http://dx.doi.org/10.1093/bioinformatics/btu435DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4201153PMC
November 2014

High correlation of the response of upper and lower lobe small airway epithelium to smoking.

PLoS One 2013 9;8(9):e72669. Epub 2013 Sep 9.

Division of Pulmonary and Critical Care Medicine, Department of Medicine, Weill Cornell Medical College, New York, New York, United States of America ; Department of Genetic Medicine, Weill Cornell Medical College, New York, New York, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0072669PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3767732PMC
June 2014

HEFT: eQTL analysis of many thousands of expressed genes while simultaneously controlling for hidden factors.

Bioinformatics 2014 Feb 4;30(3):369-76. Epub 2013 Dec 4.

Biological Statistics and Computational Biology, Cornell University, Ithaca, NY 14850, USA and Department of Genetic Medicine, Weill Cornell Medical College, New York, NY 10021, USA.

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http://bioinformatics.oxfordjournals.org/content/30/3/369.fu
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http://bioinformatics.oxfordjournals.org/cgi/doi/10.1093/bio
Publisher Site
http://dx.doi.org/10.1093/bioinformatics/btt690DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3904522PMC
February 2014

PUMA: a unified framework for penalized multiple regression analysis of GWAS data.

PLoS Comput Biol 2013 27;9(6):e1003101. Epub 2013 Jun 27.

Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, New York, United States of America.

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http://dx.doi.org/10.1371/journal.pcbi.1003101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3694815PMC
January 2014

Prevalence of the apolipoprotein E Arg145Cys dyslipidemia at-risk polymorphism in African-derived populations.

Am J Cardiol 2014 Jan 3;113(2):302-8. Epub 2013 Oct 3.

Department of Genetic Medicine, Weill Cornell Medical College, New York, New York; Department of Medicine, Weill Cornell Medical College, New York, New York. Electronic address:

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http://dx.doi.org/10.1016/j.amjcard.2013.09.021DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3943837PMC
January 2014

IQCB1 and PDE6B mutations cause similar early onset retinal degenerations in two closely related terrier dog breeds.

Invest Ophthalmol Vis Sci 2013 Oct 25;54(10):7005-19. Epub 2013 Oct 25.

Baker Institute for Animal Health, Cornell University College of Veterinary Medicine, Ithaca, New York.

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http://dx.doi.org/10.1167/iovs.13-12915DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3809947PMC
October 2013

Empirical Bayes conditional independence graphs for regulatory network recovery.

Bioinformatics 2012 Aug 8;28(15):2029-36. Epub 2012 Jun 8.

Department of Genetic Medicine, Weill Cornell Medical College, New York, NY 10065, USA.

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http://dx.doi.org/10.1093/bioinformatics/bts312DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3400959PMC
August 2012

Mouse obesity network reconstruction with a variational Bayes algorithm to employ aggressive false positive control.

BMC Bioinformatics 2012 Apr 2;13:53. Epub 2012 Apr 2.

1Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.

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http://dx.doi.org/10.1186/1471-2105-13-53DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3338387PMC
April 2012

Circulating endothelial microparticles as a measure of early lung destruction in cigarette smokers.

Am J Respir Crit Care Med 2011 Jul 11;184(2):224-32. Epub 2011 Mar 11.

Department of Genetic Medicine, Weill Cornell Medical College, New York, New York 10065, USA.

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http://dx.doi.org/10.1164/rccm.201012-2061OCDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3172886PMC
July 2011

Fast, exact linkage analysis for categorical traits on arbitrary pedigree designs.

Genet Epidemiol 2011 Jul 25;35(5):371-80. Epub 2011 Apr 25.

Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, New York, USA.

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http://dx.doi.org/10.1002/gepi.20585DOI Listing
July 2011

An ADAM9 mutation in canine cone-rod dystrophy 3 establishes homology with human cone-rod dystrophy 9.

Mol Vis 2010 Aug 11;16:1549-69. Epub 2010 Aug 11.

Baker Institute for Animal Health, Cornell University College of Veterinary Medicine, Ithaca, NY 14853-6401, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925905PMC
August 2010

Bayesian linkage analysis of categorical traits for arbitrary pedigree designs.

PLoS One 2010 Aug 26;5(8):e12307. Epub 2010 Aug 26.

Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, New York, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0012307PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2928726PMC
August 2010

A variational Bayes algorithm for fast and accurate multiple locus genome-wide association analysis.

BMC Bioinformatics 2010 Jan 27;11:58. Epub 2010 Jan 27.

Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, NY, USA.

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http://bmcbioinformatics.biomedcentral.com/articles/10.1186/
Publisher Site
http://dx.doi.org/10.1186/1471-2105-11-58DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2824680PMC
January 2010

Coordinate control of expression of Nrf2-modulated genes in the human small airway epithelium is highly responsive to cigarette smoking.

Mol Med 2009 Jul-Aug;15(7-8):203-19. Epub 2009 Mar 20.

Department of Genetic Medicine, Weill Cornell Medical College, New York, New York 10065, United States of America.

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http://dx.doi.org/10.2119/molmed.2008.00130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2707520PMC
September 2009

Coordinated evolution of co-expressed gene clusters in the Drosophila transcriptome.

BMC Evol Biol 2008 Jan 7;8. Epub 2008 Jan 7.

Department of Biological Statistics and Computational Biology, Cornell University, Ithaca, NY 14853, USA.

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http://dx.doi.org/10.1186/1471-2148-8-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266709PMC
January 2008

Quantitative trait loci for the circadian clock in Neurospora crassa.

Genetics 2007 Dec 18;177(4):2335-47. Epub 2007 Oct 18.

Department of Plant Biology, Cornell University, Ithaca, New York 14853, USA.

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http://dx.doi.org/10.1534/genetics.107.077958DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2219515PMC
December 2007

The dimensionality of genetic variation for wing shape in Drosophila melanogaster.

Evolution 2005 May;59(5):1027-38

Department of Biological Science, Florida State University, Tallahassee, Florida 32306-1100, USA.

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May 2005

Naturally segregating quantitative trait loci affecting wing shape of Drosophila melanogaster.

Genetics 2005 Apr 1;169(4):2101-13. Epub 2004 Nov 1.

Center for Population Biology and Section of Evolution and Ecology, University of California, Davis, 95616, USA.

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http://dx.doi.org/10.1534/genetics.104.036988DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1449619PMC
April 2005

Evolutionary genomics: codon bias and selection on single genomes.

Nature 2005 Jan;433(7023):E5-6; discussion E7-8

Center for Population Biology and Section of Evolution and Ecology, University of California, Davis, California 95616, USA.

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http://dx.doi.org/10.1038/nature03221DOI Listing
January 2005

Comparing G matrices: are common principal components informative?

Genetics 2003 Sep;165(1):411-25

Department of Biological Science, Florida State University, Tallahassee, Florida 32306-1100, USA.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1462744PMC
September 2003