Jason D Christie

Jason D Christie

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Jason D Christie

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Relationship of body mass index, serum creatine kinase, and acute kidney injury after severe trauma.

J Trauma Acute Care Surg 2020 Jul;89(1):179-185

From the Department of Surgery (C.R.V., D.N.H.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania; Hackensack Meridian School of Medicine at Seton Hall University (T.D.), Nutley, New Jersey; Pulmonary, Allergy, and Critical Care Division (J.P.R., C.M.F., P.N.L., J.D.C., M.G.S.S.), Center for Clinical Epidemiology and Biostatistics (D.N.H., Q.W., J.D.C., M.G.S.S.), Division of Traumatology, Surgical Critical Care, and Emergency Surgery (D.N.H.), and Center for Translational Lung Biology (J.P.R., J.D.C., M.G.S.S.), Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1097/TA.0000000000002714DOI Listing
July 2020

Discovery Through Diversity: Insights into the Genetics of Lung Function in Latino Youth.

Am J Respir Crit Care Med 2020 Jul 21. Epub 2020 Jul 21.

University of Pennsylvania, Pulmonary and Critical Care Medicine, Philadelphia, Pennsylvania, United States.

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http://dx.doi.org/10.1164/rccm.202006-2404EDDOI Listing
July 2020

An Integrative Review of the Role of Palliative Care in Lung Transplantation.

Prog Transplant 2020 06 3;30(2):147-154. Epub 2020 Apr 3.

Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1177/1526924820913512DOI Listing
June 2020

Cardiac complications and failure to rescue after injury in a mature state trauma system: Towards identifying opportunities for improvement.

Injury 2020 May 16;51(5):1216-1223. Epub 2020 Feb 16.

The University of Pennsylvania, Division of Traumatology, Critical Care and Emergency, Philadelphia, PA, United States. Electronic address:

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http://dx.doi.org/10.1016/j.injury.2020.02.003DOI Listing
May 2020

Pre-Procurement Donor Lung Tissue Gene Expression Classifies Primary Graft Dysfunction Risk.

Am J Respir Crit Care Med 2020 May 28. Epub 2020 May 28.

University of Pennsylvania Perelman School of Medicine, 14640, Philadelphia, Pennsylvania, United States.

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http://dx.doi.org/10.1164/rccm.201912-2436LEDOI Listing
May 2020

Plasma Mitochondrial DNA Levels Are Associated With ARDS in Trauma and Sepsis Patients.

Chest 2020 01 14;157(1):67-76. Epub 2019 Oct 14.

Pulmonary, Allergy and Critical Care Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA; Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA; Center for Translational Lung Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.

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http://dx.doi.org/10.1016/j.chest.2019.09.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6965693PMC
January 2020

Collagen type-V is a danger signal associated with primary graft dysfunction in lung transplantation.

Transpl Immunol 2019 10 17;56:101224. Epub 2019 Jul 17.

Pulmonary, Allergy, and Critical Care Division, University of Indiana, Indianapolis, Indiana Pulmonary, United States of America; School of Medicine, University of Virginia, Charlottesville, VA, United States of America. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09663274193004
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http://dx.doi.org/10.1016/j.trim.2019.101224DOI Listing
October 2019

The association of post-lung transplant acute kidney injury with mortality is independent of primary graft dysfunction: A cohort study.

Clin Transplant 2019 10 28;33(10):e13678. Epub 2019 Aug 28.

Pulmonary, Allergy, and Critical Care Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1111/ctr.13678DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6823116PMC
October 2019

Acute Respiratory Distress Syndrome Phenotypes.

Semin Respir Crit Care Med 2019 02 6;40(1):19-30. Epub 2019 May 6.

Division of Pulmonary, Allergy, and Critical Care, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1055/s-0039-1684049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6657496PMC
February 2019

Benchmarking emergency department thoracotomy: Using trauma video review to generate procedural norms.

Injury 2018 Sep 23;49(9):1687-1692. Epub 2018 May 23.

Division of Traumatology, Surgical Critical Care and Emergency Surgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, United States; Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, United States.

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http://dx.doi.org/10.1016/j.injury.2018.05.010DOI Listing
September 2018

Association of long pentraxin-3 with pulmonary hypertension and primary graft dysfunction in lung transplant recipients.

J Heart Lung Transplant 2018 06 20;37(6):792-794. Epub 2017 Dec 20.

Pulmonary, Allergy, and Critical Care Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA; Penn Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1016/j.healun.2017.12.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6685262PMC
June 2018

The intraosseous have it: A prospective observational study of vascular access success rates in patients in extremis using video review.

J Trauma Acute Care Surg 2018 04;84(4):558-563

From the Division of Traumatology, Surgical Critical Care and Emergency Surgery (K.M.C., R.P.D., M.J.S., P.K.K., P.M.R., L.J.K., D.N.H.), Division of Pulmonary and Critical Care (J.D.C.), and Center for Clinical Epidemiology and Biostatistics (J.D.C.), Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1097/TA.0000000000001795DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5860964PMC
April 2018

Comparative Effectiveness of Enoxaparin vs Dalteparin for Thromboprophylaxis After Traumatic Injury.

Chest 2018 01 18;153(1):133-142. Epub 2017 Aug 18.

Center for Pharmacoepidemiology Research and Training, Perelman School of Medicine, the University of Pennsylvania, Philadelphia, PA; Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, the University of Pennsylvania, Philadelphia, PA; Department of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine, the University of Pennsylvania, Philadelphia, PA.

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http://dx.doi.org/10.1016/j.chest.2017.08.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5812768PMC
January 2018

Fifty Years of Research in ARDS. Genomic Contributions and Opportunities.

Am J Respir Crit Care Med 2017 11;196(9):1113-1121

1 Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pennsylvania Perelman School of Medicine.

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http://dx.doi.org/10.1164/rccm.201702-0405CPDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5694838PMC
November 2017

A metric of our own: Failure to rescue after trauma.

J Trauma Acute Care Surg 2017 10;83(4):698-704

From the Division of Traumatology (D.N.H., P.M.R.), Surgical Critical Care and Emergency Surgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania; The Penn Injury Science Center at the University of Pennsylvania (D.N.H., M.K.D., D.J.W., P.M.R.), Philadelphia, Pennsylvania; Department of Surgery (E.J.K.), Weill-Cornell School of Medicine, New York, New York; Department of Emergency Medicine (M.K.D.), Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania; Center for Clinical Epidemiology and Biostatistics (D.J.W.), Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania; and Department of Emergency Medicine (B.G.C.), Jefferson University School of Medicine, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1097/TA.0000000000001591DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5608646PMC
October 2017

High emergency organ allocation rule in lung transplantation: a simulation study.

ERJ Open Res 2017 Oct 20;3(4). Epub 2017 Nov 20.

Service de Pneumologie B et Transplantation Pulmonaire, Hôpital Bichat et Université Paris 7, Paris, France.

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http://dx.doi.org/10.1183/23120541.00020-2017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5699881PMC
October 2017

Human lung tumor FOXP3+ Tregs upregulate four "Treg-locking" transcription factors.

JCI Insight 2017 Aug 17;2(16). Epub 2017 Aug 17.

Division of Transplant Immunology, Department of Pathology and Laboratory Medicine, and Biesecker Center for Pediatric Liver Diseases, Children's Hospital of Philadelphia and Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1172/jci.insight.94075DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5621877PMC
August 2017

Massive donor transfusion potentially increases recipient mortality after lung transplantation.

J Thorac Cardiovasc Surg 2017 05 15;153(5):1197-1203.e2. Epub 2016 Dec 15.

Division of Cardiovascular Surgery, University of Pennsylvania School of Medicine, Philadelphia, Pa. Electronic address:

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http://dx.doi.org/10.1016/j.jtcvs.2016.12.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392422PMC
May 2017

Interstitial Lung Disease in the Elderly.

Chest 2017 04 16;151(4):838-844. Epub 2016 Nov 16.

Department of Radiology, University of Pennsylvania, Pennsylvania, PA.

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http://dx.doi.org/10.1016/j.chest.2016.11.003DOI Listing
April 2017

Alveolar Type 2 Cell Transplantation in IPF: Recreating the Silver Lining.

Chest 2016 09;150(3):481-2

Pulmonary, Critical Care, and Allergy Division, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.

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http://dx.doi.org/10.1016/j.chest.2016.05.036DOI Listing
September 2016

Plasma Levels of Receptor Interacting Protein Kinase-3 (RIP3), an Essential Mediator of Necroptosis, are Associated with Acute Kidney Injury in Critically Ill Trauma Patients.

Shock 2016 08;46(2):139-43

*Pulmonary, Allergy, and Critical Care Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania †Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania ‡Center for Translational Lung Biology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania §Division of Traumatology, Surgical Critical Care, and Emergency Surgery, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania ||Center for Resuscitation Science, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania ¶Renal, Electrolyte, and Hypertension Division, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1097/SHK.0000000000000596DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4949076PMC
August 2016

Circulating markers of endothelial and alveolar epithelial dysfunction are associated with mortality in pediatric acute respiratory distress syndrome.

Intensive Care Med 2016 Jul 21;42(7):1137-45. Epub 2016 Apr 21.

Department of Bioengineering, University of Pennsylvania, 240 Skirkanich Hall, 210 South 33rd Street, Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1007/s00134-016-4352-1DOI Listing
July 2016

Survivorship Research: Studying the Past to Define the Future.

Crit Care Med 2016 07;44(7):1422-3

Pulmonary, Allergy, and Critical Care Division, Department of Medicine; and Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.

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http://dx.doi.org/10.1097/CCM.0000000000001697DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4911811PMC
July 2016

Neutropenic sepsis is associated with distinct clinical and biological characteristics: a cohort study of severe sepsis.

Crit Care 2016 07 18;20(1):222. Epub 2016 Jul 18.

Division of Pulmonary, Allergy, and Critical Care, University of Pennsylvania, Perelman School of Medicine, 3400 Spruce Street, Philadelphia, 19104, PA, USA.

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http://dx.doi.org/10.1186/s13054-016-1398-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4950810PMC
July 2016

Arginase 1 is an innate lymphoid-cell-intrinsic metabolic checkpoint controlling type 2 inflammation.

Nat Immunol 2016 06 4;17(6):656-65. Epub 2016 Apr 4.

Jill Roberts Institute for Research in Inflammatory Bowel Disease, Joan and Sanford I. Weill Department of Medicine, Department of Microbiology and Immunology, Weill Cornell Medicine, Cornell University, New York, New York, USA.

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http://dx.doi.org/10.1038/ni.3421DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4873382PMC
June 2016

Is It Possible to Prevent ARDS?

JAMA 2016 Jun;315(22):2403-5

Division of Pulmonary, Allergy, and Critical Care Medicine, Department of Medicine, University of Pennsylvania, Perelman School of Medicine, Philadelphia.

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http://dx.doi.org/10.1001/jama.2016.5988DOI Listing
June 2016

Low Plasma Levels of Adiponectin Do Not Explain Acute Respiratory Distress Syndrome Risk: a Prospective Cohort Study of Patients with Severe Sepsis.

Crit Care 2016 Mar 16;20:71. Epub 2016 Mar 16.

Division of Pulmonary, Allergy, and Critical Care, Perelman School of Medicine, University of Pennsylvania, Hospital of the University of Pennsylvania, 3400 Spruce Street, Philadelphia, PA, 19104, USA.

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http://dx.doi.org/10.1186/s13054-016-1244-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4794929PMC
March 2016

The ABO Histo-Blood Group and AKI in Critically Ill Patients with Trauma or Sepsis.

Clin J Am Soc Nephrol 2015 Nov 4;10(11):1911-20. Epub 2015 Sep 4.

Divisions of Pulmonary, Allergy, and Critical Care and Center for Clinical Epidemiology and Biostatistics, and.

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http://dx.doi.org/10.2215/CJN.12201214DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4633800PMC
November 2015

Primary graft dysfunction: lessons learned about the first 72 h after lung transplantation.

Curr Opin Organ Transplant 2015 Oct;20(5):506-14

aDepartment of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA bCenter for Clinical Epidemiology and Biostatistics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1097/MOT.0000000000000232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4624097PMC
October 2015

A Randomized Dose-Escalation Study of the Safety and Anti-Inflammatory Activity of the p38 Mitogen-Activated Protein Kinase Inhibitor Dilmapimod in Severe Trauma Subjects at Risk for Acute Respiratory Distress Syndrome.

Crit Care Med 2015 Sep;43(9):1859-69

1Pulmonary and Critical Care Medicine, University of Pennsylvania School of Medicine, Center for Clinical Epidemiology and Biostatistics, Philadelphia, PA. 2Department of Surgery, Duke University Medical Center, Durham, NC. 3Department of Surgery, University of Kentucky, Lexington, KY. 4Division of Trauma and Surgical Critical Care, Vanderbilt University Medical Center, Nashville, TN. 5Department of Critical Care Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA. 6GlaxoSmithKline, Stockley Park, UK. 7GlaxoSmithKline, Stevenage, UK. 8GlaxoSmithKline, King of Prussia, PA.

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http://dx.doi.org/10.1097/CCM.0000000000001132DOI Listing
September 2015

Primed for Injury: Cigarette Smokers and Acute Respiratory Distress Syndrome.

Crit Care Med 2015 Sep;43(9):2015-6

Division of Pulmonary, Allergy, and Critical Care Medicine, Center for Translational Lung Biology, University of Pennsylvania, Perelman School of Medicine, Philadelphia, PA.

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http://dx.doi.org/10.1097/CCM.0000000000001121DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4538990PMC
September 2015

Hospital-based acute care use in survivors of septic shock.

Crit Care Med 2015 Apr;43(4):729-37

1Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA. 2Department of Emergency Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA. 3Pulmonary, Allergy, and Critical Care Division, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA. 4Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA. 5Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA. 6The Wharton School, University of Pennsylvania, Philadelphia, PA. 7The Commonwealth Medical College, Scranton, PA.

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http://dx.doi.org/10.1097/CCM.0000000000000693DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4359663PMC
April 2015

Prehospital aspirin use and acute respiratory distress syndrome--a case for aspirin in the drinking water?

Crit Care Med 2015 Apr;43(4):916-7

Division of Pulmonary, Allergy, and Critical Care Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA Division of Pulmonary, Allergy, and Critical Care Medicine, Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA.

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http://dx.doi.org/10.1097/CCM.0000000000000835DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4360909PMC
April 2015

Linking genetics to ARDS pathogenesis: the role of the platelet.

Chest 2015 Mar;147(3):585-586

Division of Pulmonary, Allergy and Critical Care Medicine, Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.

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http://dx.doi.org/10.1378/chest.14-2701DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4364315PMC
March 2015

Epidemiology and outcomes in patients with severe sepsis admitted to the hospital wards.

J Crit Care 2015 Feb 22;30(1):78-84. Epub 2014 Jul 22.

Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA; Department of Emergency Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA. Electronic address:

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http://dx.doi.org/10.1016/j.jcrc.2014.07.012DOI Listing
February 2015

Oxidant stress regulatory genetic variation in recipients and donors contributes to risk of primary graft dysfunction after lung transplantation.

J Thorac Cardiovasc Surg 2015 Feb 28;149(2):596-602. Epub 2014 Sep 28.

Pulmonary, Allergy, and Critical Care Division, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pa; Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania Perelman School of Medicine, Division of Oncology, Philadelphia, Pa.

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http://dx.doi.org/10.1016/j.jtcvs.2014.09.077DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4346512PMC
February 2015

Lung size mismatch and primary graft dysfunction after bilateral lung transplantation.

J Heart Lung Transplant 2015 Feb 28;34(2):233-40. Epub 2014 Sep 28.

Division of Pulmonary and Critical Care Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania.

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http://dx.doi.org/10.1016/j.healun.2014.09.030DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4329253PMC
February 2015

Response.

Chest 2015 Feb;147(2):e67-e68

Center for Clinical Epidemiology and Biostatistics, Perelman School of Medicine at the University of Pennsylvania. Philadelphia, PA; Division of Pulmonary, Allergy, and Critical Care, Perelman School of Medicine at the University of Pennsylvania. Philadelphia, PA.

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http://dx.doi.org/10.1378/chest.14-2627DOI Listing
February 2015

Response to letter by Dr. M. S. A. Mohamed (Antagonizing reactive oxygen species during lung perfusion).

Am J Physiol Lung Cell Mol Physiol 2014 Dec;307(11):L909

Institute for Environmental Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania;

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http://dx.doi.org/10.1152/ajplung.00310.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888544PMC
December 2014

Shear stress-related mechanosignaling with lung ischemia: lessons from basic research can inform lung transplantation.

Am J Physiol Lung Cell Mol Physiol 2014 Nov 19;307(9):L668-80. Epub 2014 Sep 19.

Institute for Environmental Medicine, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennyslvania;

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http://dx.doi.org/10.1152/ajplung.00198.2014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217004PMC
November 2014