Publications by authors named "Jarno Drost"

31Publications

Organoid models of childhood kidney tumours.

Nat Rev Urol 2020 Jun;17(6):311-313

Princess Máxima Center for Pediatric Oncology, Utrecht, Netherlands.

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http://dx.doi.org/10.1038/s41585-020-0315-yDOI Listing
June 2020

Xenograft and organoid model systems in cancer research.

EMBO J 2019 08 8;38(15):e101654. Epub 2019 Jul 8.

Oncode Institute, Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.

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http://dx.doi.org/10.15252/embj.2019101654DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6670015PMC
August 2019

Profiling proliferative cells and their progeny in damaged murine hearts.

Proc Natl Acad Sci U S A 2018 12 7;115(52):E12245-E12254. Epub 2018 Dec 7.

Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University Medical Centre Utrecht, 3584 CT Utrecht, The Netherlands;

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http://dx.doi.org/10.1073/pnas.1805829115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6310797PMC
December 2018

Organoids in cancer research.

Nat Rev Cancer 2018 07;18(7):407-418

Princess Máxima Centre for Paediatric Oncology, Utrecht, Netherlands.

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http://www.nature.com/articles/s41568-018-0007-6
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http://dx.doi.org/10.1038/s41568-018-0007-6DOI Listing
July 2018

A surgical orthotopic organoid transplantation approach in mice to visualize and study colorectal cancer progression.

Nat Protoc 2018 02 4;13(2):235-247. Epub 2018 Jan 4.

Princess Máxima Center for Pediatric Oncology, Utrecht, The Netherlands.

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http://dx.doi.org/10.1038/nprot.2017.137DOI Listing
February 2018

Use of CRISPR-modified human stem cell organoids to study the origin of mutational signatures in cancer.

Science 2017 10 14;358(6360):234-238. Epub 2017 Sep 14.

Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and University Medical Center (UMC) Utrecht, 3584CT Utrecht, Netherlands.

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http://dx.doi.org/10.1126/science.aao3130DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6038908PMC
October 2017

Translational applications of adult stem cell-derived organoids.

Development 2017 03;144(6):968-975

Cancer Genomics Netherlands, UMC Utrecht, Utrecht 3584CG, The Netherlands.

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http://dx.doi.org/10.1242/dev.140566DOI Listing
March 2017

Genetic dissection of colorectal cancer progression by orthotopic transplantation of engineered cancer organoids.

Proc Natl Acad Sci U S A 2017 03 7;114(12):E2357-E2364. Epub 2017 Mar 7.

Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University Medical Center (UMC) Utrecht, 3584 CT Utrecht, The Netherlands;

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http://dx.doi.org/10.1073/pnas.1701219114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5373343PMC
March 2017

The Generation of Organoids for Studying Wnt Signaling.

Methods Mol Biol 2016 ;1481:141-59

Hubrecht Institute-KNAW and University Medical Center Utrecht, Uppsalalaan 8, 3584 CT, Utrecht, The Netherlands.

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http://dx.doi.org/10.1007/978-1-4939-6393-5_15DOI Listing
January 2018

Who Is in the Driver's Seat: Tracing Cancer Genes Using CRISPR-Barcoding.

Mol Cell 2016 08;63(3):352-4

Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and UMC Utrecht, 3584CT Utrecht, the Netherlands; Cancer Genomics Netherlands, UMC Utrecht, 3584CG Utrecht, the Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2016.07.013DOI Listing
August 2016

TGFβ signaling directs serrated adenomas to the mesenchymal colorectal cancer subtype.

EMBO Mol Med 2016 07 1;8(7):745-60. Epub 2016 Jul 1.

Laboratory for Experimental Oncology and Radiobiology (LEXOR), Center for Experimental Molecular Medicine (CEMM), Academic Medical Center (AMC), University of Amsterdam, Amsterdam, The Netherlands Cancer Genomics Center, Amsterdam, The Netherlands

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http://dx.doi.org/10.15252/emmm.201606184DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931289PMC
July 2016

Organoid culture systems for prostate epithelial and cancer tissue.

Nat Protoc 2016 Feb 21;11(2):347-58. Epub 2016 Jan 21.

Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and University Medical Center (UMC) Utrecht, Utrecht, the Netherlands.

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http://dx.doi.org/10.1038/nprot.2016.006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4793718PMC
February 2016

Sequential cancer mutations in cultured human intestinal stem cells.

Nature 2015 May 29;521(7550):43-7. Epub 2015 Apr 29.

1] Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences (KNAW) and UMC Utrecht, 3584CT Utrecht, The Netherlands [2] Cancer Genomics Netherlands, UMC Utrecht, 3584CG Utrecht, The Netherlands.

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http://dx.doi.org/10.1038/nature14415DOI Listing
May 2015

Identification of multipotent luminal progenitor cells in human prostate organoid cultures.

Cell 2014 Sep 4;159(1):163-175. Epub 2014 Sep 4.

Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and University Medical Center Utrecht, 3584 CT, Utrecht, Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2014.08.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4772677PMC
September 2014

eRNAs are required for p53-dependent enhancer activity and gene transcription.

Mol Cell 2013 Feb 27;49(3):524-35. Epub 2012 Dec 27.

Division of Gene Regulation, the Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX, Amsterdam, the Netherlands; Doctoral Programme in Biomedicine and Experimental Biology, Centre for Neuroscience and Cell Biology, 3004-517 Coimbra, Portugal.

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http://dx.doi.org/10.1016/j.molcel.2012.11.021DOI Listing
February 2013

The poly(A)-binding protein nuclear 1 suppresses alternative cleavage and polyadenylation sites.

Cell 2012 Apr 12;149(3):538-53. Epub 2012 Apr 12.

Division of Gene Regulation, The Netherlands Cancer Institute, Plesmanlaan 121, 1066 CX Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.cell.2012.03.022DOI Listing
April 2012

Gene regulation and tumor suppression by the bromodomain-containing protein BRD7.

Cell Cycle 2010 Jul 7;9(14):2777-81. Epub 2010 Jul 7.

Laboratorio Nazionale CIB, Area Science Park, Trieste, Italy.

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July 2010

BRD7 is a candidate tumour suppressor gene required for p53 function.

Nat Cell Biol 2010 Apr 14;12(4):380-9. Epub 2010 Mar 14.

The Netherlands Cancer Institute, Division of Gene Regulation, Plesmanlaan 121, 1066CX, Amsterdam, The Netherlands.

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http://www.nature.com/articles/ncb2038
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http://dx.doi.org/10.1038/ncb2038DOI Listing
April 2010

Transformation locked in a loop.

Cell 2009 Nov;139(4):654-6

Division of Gene Regulation, The Netherlands Cancer Institute, 1066 CX Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.cell.2009.10.035DOI Listing
November 2009