Jared C Roach

Jared C Roach

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Jared C Roach

Jared C Roach

Publications by authors named "Jared C Roach"

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45Publications

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Population-specific genetic modification of Huntington's disease in Venezuela.

PLoS Genet 2018 05 11;14(5):e1007274. Epub 2018 May 11.

Molecular Neurogenetics Unit, Center for Genomic Medicine, Massachusetts General Hospital, Boston, Massachusetts, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1007274DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5965898PMC
May 2018

Parent-of-origin-specific signatures of de novo mutations.

Nat Genet 2016 08 20;48(8):935-9. Epub 2016 Jun 20.

Inova Translational Medicine Institute (ITMI), Inova Health Systems, Falls Church, Virginia, USA.

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http://dx.doi.org/10.1038/ng.3597DOI Listing
August 2016

Sequence-Level Analysis of the Major European Huntington Disease Haplotype.

Am J Hum Genet 2015 Sep 27;97(3):435-44. Epub 2015 Aug 27.

Center for Human Genetic Research, Massachusetts General Hospital, Boston, MA 02114, USA; Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA 02142, USA; Department of Genetics, Harvard Medical School, Boston, MA 02115, USA.

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http://dx.doi.org/10.1016/j.ajhg.2015.07.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564985PMC
September 2015

Whole-genome sequencing of the world's oldest people.

PLoS One 2014 12;9(11):e112430. Epub 2014 Nov 12.

Depts. of Developmental Biology and Genetics, Stanford University, Stanford, CA, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0112430PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4229186PMC
July 2015

Whole-genome haplotyping approaches and genomic medicine.

Genome Med 2014 25;6(9):73. Epub 2014 Sep 25.

Institute for Systems Biology, Terry Avenue North, Seattle, WA 98109 USA.

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http://dx.doi.org/10.1186/s13073-014-0073-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4254418PMC
December 2014

Accurate and robust prediction of genetic relationship from whole-genome sequences.

PLoS One 2014 28;9(2):e85437. Epub 2014 Feb 28.

Institute for Systems Biology, Seattle, Washington, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0085437PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3938395PMC
November 2014

Diffuse angiopathy in Adams-Oliver syndrome associated with truncating DOCK6 mutations.

Am J Med Genet A 2014 Oct 4;164A(10):2656-62. Epub 2014 Aug 4.

Department of Medical Genetics and Child and Family Research Institute, University of British Columbia, Vancouver, Canada.

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http://dx.doi.org/10.1002/ajmg.a.36685DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4167472PMC
October 2014

Mutations in NOTCH1 cause Adams-Oliver syndrome.

Am J Hum Genet 2014 Sep 14;95(3):275-84. Epub 2014 Aug 14.

Department of Medical Genetics and Child and Family Research Institute, University of British Columbia, Vancouver, BC V6H 3N1, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.ajhg.2014.07.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4157158PMC
September 2014

An international effort towards developing standards for best practices in analysis, interpretation and reporting of clinical genome sequencing results in the CLARITY Challenge.

Authors:
Catherine A Brownstein Alan H Beggs Nils Homer Barry Merriman Timothy W Yu Katherine C Flannery Elizabeth T DeChene Meghan C Towne Sarah K Savage Emily N Price Ingrid A Holm Lovelace J Luquette Elaine Lyon Joseph Majzoub Peter Neupert David McCallie Peter Szolovits Huntington F Willard Nancy J Mendelsohn Renee Temme Richard S Finkel Sabrina W Yum Livija Medne Shamil R Sunyaev Ivan Adzhubey Christopher A Cassa Paul I W de Bakker Hatice Duzkale Piotr Dworzyński William Fairbrother Laurent Francioli Birgit H Funke Monica A Giovanni Robert E Handsaker Kasper Lage Matthew S Lebo Monkol Lek Ignaty Leshchiner Daniel G MacArthur Heather M McLaughlin Michael F Murray Tune H Pers Paz P Polak Soumya Raychaudhuri Heidi L Rehm Rachel Soemedi Nathan O Stitziel Sara Vestecka Jochen Supper Claudia Gugenmus Bernward Klocke Alexander Hahn Max Schubach Mortiz Menzel Saskia Biskup Peter Freisinger Mario Deng Martin Braun Sven Perner Richard J H Smith Janeen L Andorf Jian Huang Kelli Ryckman Val C Sheffield Edwin M Stone Thomas Bair E Ann Black-Ziegelbein Terry A Braun Benjamin Darbro Adam P DeLuca Diana L Kolbe Todd E Scheetz Aiden E Shearer Rama Sompallae Kai Wang Alexander G Bassuk Erik Edens Katherine Mathews Steven A Moore Oleg A Shchelochkov Pamela Trapane Aaron Bossler Colleen A Campbell Jonathan W Heusel Anne Kwitek Tara Maga Karin Panzer Thomas Wassink Douglas Van Daele Hela Azaiez Kevin Booth Nic Meyer Michael M Segal Marc S Williams Gerard Tromp Peter White Donald Corsmeier Sara Fitzgerald-Butt Gail Herman Devon Lamb-Thrush Kim L McBride David Newsom Christopher R Pierson Alexander T Rakowsky Aleš Maver Luca Lovrečić Anja Palandačić Borut Peterlin Ali Torkamani Anna Wedell Mikael Huss Andrey Alexeyenko Jessica M Lindvall Måns Magnusson Daniel Nilsson Henrik Stranneheim Fulya Taylan Christian Gilissen Alexander Hoischen Bregje van Bon Helger Yntema Marcel Nelen Weidong Zhang Jason Sager Lu Zhang Kathryn Blair Deniz Kural Michael Cariaso Greg G Lennon Asif Javed Saloni Agrawal Pauline C Ng Komal S Sandhu Shuba Krishna Vamsi Veeramachaneni Ofer Isakov Eran Halperin Eitan Friedman Noam Shomron Gustavo Glusman Jared C Roach Juan Caballero Hannah C Cox Denise Mauldin Seth A Ament Lee Rowen Daniel R Richards F Anthony San Lucas Manuel L Gonzalez-Garay C Thomas Caskey Yu Bai Ying Huang Fang Fang Yan Zhang Zhengyuan Wang Jorge Barrera Juan M Garcia-Lobo Domingo González-Lamuño Javier Llorca Maria C Rodriguez Ignacio Varela Martin G Reese Francisco M De La Vega Edward Kiruluta Michele Cargill Reece K Hart Jon M Sorenson Gholson J Lyon David A Stevenson Bruce E Bray Barry M Moore Karen Eilbeck Mark Yandell Hongyu Zhao Lin Hou Xiaowei Chen Xiting Yan Mengjie Chen Cong Li Can Yang Murat Gunel Peining Li Yong Kong Austin C Alexander Zayed I Albertyn Kym M Boycott Dennis E Bulman Paul M K Gordon A Micheil Innes Bartha M Knoppers Jacek Majewski Christian R Marshall Jillian S Parboosingh Sarah L Sawyer Mark E Samuels Jeremy Schwartzentruber Isaac S Kohane David M Margulies

Genome Biol 2014 Mar 25;15(3):R53. Epub 2014 Mar 25.

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http://dx.doi.org/10.1186/gb-2014-15-3-r53DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4073084PMC
March 2014

Relationship estimation from whole-genome sequence data.

PLoS Genet 2014 Jan 30;10(1):e1004144. Epub 2014 Jan 30.

Department of Epidemiology, The University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America.

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http://dx.doi.org/10.1371/journal.pgen.1004144DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3907355PMC
January 2014

Predictive Analytics In Healthcare: Medications as a Predictor of Medical Complexity.

Big Data 2013 Dec 5;1(4):237-44. Epub 2013 Dec 5.

1 Bioinformatics and High-Throughput Data Analysis Laboratory, Seattle Children's Research Institute , Seattle, Washington.

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http://dx.doi.org/10.1089/big.2013.0024DOI Listing
December 2013

Kaviar: an accessible system for testing SNV novelty.

Bioinformatics 2011 Nov 28;27(22):3216-7. Epub 2011 Sep 28.

Institute for Systems Biology, Seattle, WA 98109, USA.

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http://dx.doi.org/10.1093/bioinformatics/btr540DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208392PMC
November 2011

TFCat: the curated catalog of mouse and human transcription factors.

Genome Biol 2009 12;10(3):R29. Epub 2009 Mar 12.

Department of Medical Genetics, Centre for Molecular Medicine and Therapeutics, Child and Family Research Institute, University of British Columbia, Vancouver, Canada.

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http://dx.doi.org/10.1186/gb-2009-10-3-r29DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2691000PMC
July 2009

Endotoxin recognition: in fish or not in fish?

FEBS Lett 2005 Dec 9;579(29):6519-28. Epub 2005 Nov 9.

Great Lakes WATER Institute, University of Wisconsin-Milwaukee, 600 E. Greenfield Ave., Milwaukee, WI 53204, USA.

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http://doi.wiley.com/10.1016/j.febslet.2005.10.061
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http://dx.doi.org/10.1016/j.febslet.2005.10.061DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1365396PMC
December 2005

Evolutionary algorithms for the selection of single nucleotide polymorphisms.

BMC Bioinformatics 2003 Jul 23;4:30. Epub 2003 Jul 23.

Institute for Systems Biology, Seattle, WA, USA.

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http://dx.doi.org/10.1186/1471-2105-4-30DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC183839PMC
July 2003

A clade of trypsins found in cold-adapted fish.

Authors:
Jared C Roach

Proteins 2002 Apr;47(1):31-44

Institute for Systems Biology, Seattle, Washington 98103, USA.

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April 2002

Genomic analysis of the olfactory receptor region of the mouse and human T-cell receptor alpha/delta loci.

Genome Res 2002 Jan;12(1):81-7

Department of Molecular Biotechnology, University of Washington, Seattle, Washington 98195, USA.

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http://dx.doi.org/10.1101/gr.197901DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC155264PMC
January 2002