Janice Robertson

Janice Robertson

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Occupancy distributions of membrane proteins in heterogeneous liposome populations.

Biochim Biophys Acta Biomembr 2020 Jan 5;1862(1):183033. Epub 2019 Aug 5.

Department of Molecular Physiology and Biophysics, The University of Iowa, Iowa City, IA, United States of America; Department of Biochemistry and Molecular Biophysics, Washington University, St. Louis, MO, United States of America. Electronic address:

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http://dx.doi.org/10.1016/j.bbamem.2019.183033DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6899186PMC
January 2020

Synaptic localization of C9orf72 regulates post-synaptic glutamate receptor 1 levels.

Acta Neuropathol Commun 2019 Oct 24;7(1):161. Epub 2019 Oct 24.

Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Krembil Discovery Tower, 60 Leonard Ave., 4th floor - 4KD-481, Toronto, ON, M5T 0S8, Canada.

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http://dx.doi.org/10.1186/s40478-019-0812-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6813971PMC
October 2019

Somatic expansion of the hexanucleotide repeat does not occur in ALS spinal cord tissues.

Neurol Genet 2019 Apr 19;5(2):e317. Epub 2019 Mar 19.

Department of Human Genetics (J.P.R., G.A.R.), McGill University, Montréal, Quebec, Canada; Montreal Neurological Institute and Hospital (J.P.R., H.C., P.A.D., G.A.R.), McGill University, Montréal, Quebec, Canada; Pasteur Institute (C.S.L.), University Paris Diderot, Sorbonne Paris Cité, Paris, France; Department of Neurology and Neurosurgery (H.C., P.A.D., G.A.R.), McGill University, Montréal, Quebec, Canada; Department of Clinical Neurological Sciences and Robarts Research Institute (K.V., M.S.A.N.N.), Schulich School of Medicine and Dentistry, Western University, London, Ontario, Canada; Sunnybrook Health Sciences Centre (L.Z.); and Tanz Centre for Research in Neurodegenerative Diseases (J.R.), University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1212/NXG.0000000000000317DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454309PMC
April 2019

Interrogating the conformational dynamics of BetP transport.

J Gen Physiol 2019 Mar 13;151(3):279-281. Epub 2019 Feb 13.

Department of Biochemistry and Molecular Biophysics, Washington University, St. Louis, MO

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http://dx.doi.org/10.1085/jgp.201812315DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400519PMC
March 2019

Membrane physiologists of all kinds meet at Woods Hole.

J Gen Physiol 2019 Mar 22;151(3):273. Epub 2019 Feb 22.

Theoretical Molecular Biophysics Laboratory, National Heart, Lung & Blood Institute, National Institutes of Health, Bethesda, MD

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http://dx.doi.org/10.1085/jgp.201912340DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6400522PMC
March 2019

Physiologically Important Electrolytes as Regulators of TDP-43 Aggregation and Droplet-Phase Behavior.

Biochemistry 2019 02 13;58(6):590-607. Epub 2018 Dec 13.

University Health Network, Princess Margaret Cancer Centre , University of Toronto , TMDT 4-305, 101 College Street , Toronto , ON M5G 1L7 , Canada.

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http://dx.doi.org/10.1021/acs.biochem.8b00842DOI Listing
February 2019

MicroRNA Expression Levels Are Altered in the Cerebrospinal Fluid of Patients with Young-Onset Alzheimer's Disease.

Mol Neurobiol 2018 Dec 30;55(12):8826-8841. Epub 2018 Mar 30.

Tanz Centre for Research in Neurodegenerative Diseases, Krembil Discovery Tower, 60 Leonard Ave., 4KD-481, Toronto, ON, M5T 2S8, Canada.

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http://dx.doi.org/10.1007/s12035-018-1032-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208843PMC
December 2018

Nodding syndrome in Uganda is a tauopathy.

Acta Neuropathol 2018 11 15;136(5):691-697. Epub 2018 Sep 15.

Ontario Forensic Pathology Service, Toronto, ON, Canada.

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http://link.springer.com/10.1007/s00401-018-1909-9
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http://dx.doi.org/10.1007/s00401-018-1909-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6208726PMC
November 2018

The lipid bilayer membrane and its protein constituents.

J Gen Physiol 2018 11 25;150(11):1472-1483. Epub 2018 Sep 25.

Department of Molecular Physiology and Biophysics, The University of Iowa, Iowa City, IA.

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http://dx.doi.org/10.1085/jgp.201812153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219687PMC
November 2018

Mechanisms Associated with TDP-43 Neurotoxicity in ALS/FTLD.

Adv Neurobiol 2018 ;20:239-263

Tanz Centre for Research in Neurodegenerative Diseases and Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, M5T 2S8, Canada.

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http://link.springer.com/10.1007/978-3-319-89689-2_9
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http://dx.doi.org/10.1007/978-3-319-89689-2_9DOI Listing
October 2018

A C6orf10/LOC101929163 locus is associated with age of onset in C9orf72 carriers.

Brain 2018 10;141(10):2895-2907

Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1093/brain/awy238DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6158742PMC
October 2018

Clinical Reasoning: A 42-year-old man with unilateral leg weakness.

Neurology 2018 03;90(12):e1085-e1090

From the Department of Medicine, Division of Neurology (R.S., L.Z.), and Department of Anatomical Pathology (J.K.), Sunnybrook Health Sciences Centre, and Tanz Centre for Research in Neurodegenerative Disease (R.S., A.W., E.R., J.R.), University of Toronto, Canada.

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http://dx.doi.org/10.1212/WNL.0000000000005179DOI Listing
March 2018

Immunohistochemical detection of C9orf72 protein in frontotemporal lobar degeneration and motor neurone disease: patterns of immunostaining and an evaluation of commercial antibodies.

Amyotroph Lateral Scler Frontotemporal Degener 2018 02 2;19(1-2):102-111. Epub 2017 Aug 2.

a Division of Neuroscience and Experimental Psychology, School of Biological Sciences, Faculty of Biology, Medicine and Health , University of Manchester, Salford Royal Hospital , Salford , UK.

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http://dx.doi.org/10.1080/21678421.2017.1359304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836993PMC
February 2018

A model-free method for measuring dimerization free energies of CLC-ec1 in lipid bilayers.

J Gen Physiol 2018 02 10;150(2):355-365. Epub 2018 Jan 10.

Department of Molecular Physiology and Biophysics, The University of Iowa, Iowa City, IA

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http://dx.doi.org/10.1085/jgp.201711893DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5806674PMC
February 2018

Unaffected mosaic case: RNA foci, dipeptide proteins, but upregulated C9orf72 expression.

Neurology 2018 01 27;90(4):e323-e331. Epub 2017 Dec 27.

From the Tanz Centre for Research in Neurodegenerative Diseases (P.M., M.Z., C.S., D.M., S.X., A.B.Z., P.M.M., A.W., R.S., J.R., E.R.), Department of Medicine (L.Z., E.R.), Division of Neurology, and Department of Laboratory Medicine and Pathobiology (J.R.), University of Toronto, Ontario, Canada; Department of Neuroscience (M.v.B., L.P., R.R.), Mayo Clinic, Jacksonville, FL; and Sunnybrook Health Sciences Centre (J.K., L.Z.), Toronto, Ontario, Canada.

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http://dx.doi.org/10.1212/WNL.0000000000004865DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798652PMC
January 2018

Dysregulation of chromatin remodelling complexes in amyotrophic lateral sclerosis.

Hum Mol Genet 2017 11;26(21):4142-4152

Department of Neurology and Neurosurgery and the Montreal Neurological Institute, McGill University, Montreal, QC H3A 2B3, Canada.

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http://academic.oup.com/hmg/article/26/21/4142/4036437/Dysre
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http://dx.doi.org/10.1093/hmg/ddx301DOI Listing
November 2017

Cholinergic neuron gene expression differences captured by translational profiling in a mouse model of Alzheimer's disease.

Neurobiol Aging 2017 09 25;57:104-119. Epub 2017 May 25.

Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada. Electronic address:

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http://dx.doi.org/10.1016/j.neurobiolaging.2017.05.014DOI Listing
September 2017

DNA methylation age-acceleration is associated with disease duration and age at onset in C9orf72 patients.

Acta Neuropathol 2017 08 24;134(2):271-279. Epub 2017 Apr 24.

Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, 60 Leonard Ave., Toronto, ON, M5T 2S8, Canada.

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http://dx.doi.org/10.1007/s00401-017-1713-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5508035PMC
August 2017

Cellular encoding of Cy dyes for single-molecule imaging.

Elife 2016 12 12;5. Epub 2016 Dec 12.

Department of Molecular Physiology and Biophysics, University of Iowa Carver College of Medicine, Iowa City, United States.

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http://dx.doi.org/10.7554/eLife.19088DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5207767PMC
December 2016

Genetic and epigenetic study of ALS-discordant identical twins with double mutations in SOD1 and ARHGEF28.

J Neurol Neurosurg Psychiatry 2016 11 6;87(11):1268-1270. Epub 2016 May 6.

Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada Division of Neurology, Department of Medicine, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1136/jnnp-2016-313592DOI Listing
November 2016

C9orf72 isoforms in Amyotrophic Lateral Sclerosis and Frontotemporal Lobar Degeneration.

Brain Res 2016 09 29;1647:43-49. Epub 2016 Apr 29.

Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Canada; Department of Laboratory Medicine and Pathobiology, University of Toronto, Canada. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00068993163031
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http://dx.doi.org/10.1016/j.brainres.2016.04.062DOI Listing
September 2016

MTHFSD and DDX58 are novel RNA-binding proteins abnormally regulated in amyotrophic lateral sclerosis.

Brain 2016 Jan 2;139(Pt 1):86-100. Epub 2015 Nov 2.

1 Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, ON, M5T 2S8, Canada 2 Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, M5S 1A1, Canada

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http://dx.doi.org/10.1093/brain/awv308DOI Listing
January 2016

Isoform-specific antibodies reveal distinct subcellular localizations of C9orf72 in amyotrophic lateral sclerosis.

Ann Neurol 2015 Oct 29;78(4):568-83. Epub 2015 Aug 29.

Tanz Center for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/ana.24469DOI Listing
October 2015

Gene targeting of mouse Tardbp negatively affects Masp2 expression.

PLoS One 2014 16;9(4):e95373. Epub 2014 Apr 16.

Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, ON, Canada.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0095373PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3989299PMC
June 2015

A two-hybrid screen identifies an unconventional role for the intermediate filament peripherin in regulating the subcellular distribution of the SNAP25-interacting protein, SIP30.

J Neurochem 2014 Dec 4;131(5):588-601. Epub 2014 Sep 4.

Montreal Neurological Institute and Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, Canada.

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http://dx.doi.org/10.1111/jnc.12928DOI Listing
December 2014

An α2-Na/K ATPase/α-adducin complex in astrocytes triggers non-cell autonomous neurodegeneration.

Nat Neurosci 2014 Dec 26;17(12):1710-9. Epub 2014 Oct 26.

1] Department of Neurobiology, Harvard Medical School, Boston, Massachusetts, USA. [2] Department of Anatomy and Neurobiology, Washington University School of Medicine, St. Louis, Missouri, USA.

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http://dx.doi.org/10.1038/nn.3853DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4703324PMC
December 2014

ALS-associated peripherin spliced transcripts form distinct protein inclusions that are neuroprotective against oxidative stress.

Exp Neurol 2014 Nov 4;261:217-29. Epub 2014 Jun 4.

Neuroregeneration Research Institute, McLean Hospital, Harvard Medical School, Belmont, MA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.expneurol.2014.05.024DOI Listing
November 2014

Hypermethylation of the CpG-island near the C9orf72 G₄C₂-repeat expansion in FTLD patients.

Hum Mol Genet 2014 Nov 6;23(21):5630-7. Epub 2014 Jun 6.

Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, 60 Leonard Street, Toronto, Ontario, Canada M5T 2S8, Department of Medicine, Division of Neurology, University of Toronto, 1 King's College Circle, Toronto, Ontario, Canada M5S 1A8 and

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http://dx.doi.org/10.1093/hmg/ddu279DOI Listing
November 2014

Identical twins with the C9orf72 repeat expansion are discordant for ALS.

Neurology 2014 Oct 10;83(16):1476-8. Epub 2014 Sep 10.

From the Tanz Centre for Research in Neurodegenerative Diseases (Z.X., S.D., M.G., D.M., C.S., Y.L., J.R., E.R.) and Division of Neurology (L.Z., E.R.), University of Toronto (Y.Y.); Sunnybrook Health Sciences Centre (Y.Y., L.Z.), Toronto, Canada; Mayo Clinic (M.v.B., R.R.), Jacksonville, FL; and the Laboratory of Neurogenetics (A.S.), National Institute on Aging, Bethesda, MD.

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http://dx.doi.org/10.1212/WNL.0000000000000886DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4206161PMC
October 2014

Wild-type Cu/Zn superoxide dismutase stabilizes mutant variants by heterodimerization.

Neurobiol Dis 2014 Feb 4;62:479-88. Epub 2013 Nov 4.

Institute for Pathobiochemistry, University Medical Center, Johannes Gutenberg-University Mainz, Duesbergweg 6, 55128 Mainz, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2013.10.027DOI Listing
February 2014

A family of fluoride-specific ion channels with dual-topology architecture.

Elife 2013 Aug 27;2:e01084. Epub 2013 Aug 27.

Department of Biochemistry , Howard Hughes Medical Institute, Brandeis University , Waltham , United States.

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http://dx.doi.org/10.7554/eLife.01084DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3755343PMC
August 2013

Hypermethylation of the CpG island near the G4C2 repeat in ALS with a C9orf72 expansion.

Am J Hum Genet 2013 Jun 23;92(6):981-9. Epub 2013 May 23.

Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, 6 Queen's Park Crescent West, Toronto, ON M5S 3H2, Canada.

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http://dx.doi.org/10.1016/j.ajhg.2013.04.017DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3675239PMC
June 2013

ALS Untangled No. 20: the Deanna protocol.

Amyotroph Lateral Scler Frontotemporal Degener 2013 May 2;14(4):319-23. Epub 2013 May 2.

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http://dx.doi.org/10.3109/21678421.2013.788405DOI Listing
May 2013

Isoform-specific expression and ratio changes accompany oxidant-induced peripherin aggregation in a neuroblastoma cell line.

Brain Res 2011 Nov 22;1422:57-65. Epub 2011 Sep 22.

Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, ON, Canada.

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http://dx.doi.org/10.1016/j.brainres.2011.09.032DOI Listing
November 2011

Pathological hallmarks of amyotrophic lateral sclerosis/frontotemporal lobar degeneration in transgenic mice produced with TDP-43 genomic fragments.

Brain 2011 Sep 13;134(Pt 9):2610-26. Epub 2011 Jul 13.

Centre de Recherche du Centre Hospitalier Universitaire de Québec, Pavillon CHUL, 2705 Boulevard Laurier, Quebec, QC G1V 4G2, Canada.

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http://dx.doi.org/10.1093/brain/awr159DOI Listing
September 2011

RNA targets of TDP-43 identified by UV-CLIP are deregulated in ALS.

Mol Cell Neurosci 2011 Jul 21;47(3):167-80. Epub 2011 Mar 21.

Centre for Research in Neurodegenerative Diseases, Department of Laboratory Medicine and Pathobiology, University of Toronto, 6 Queen's Park Crescent West, Toronto, Ontario, Canada M5S 3H2.

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http://dx.doi.org/10.1016/j.mcn.2011.02.013DOI Listing
July 2011

Ion access pathway to the transmembrane pore in P2X receptor channels.

J Gen Physiol 2011 Jun;137(6):579-90

Porter Neuroscience Research Center, Molecular Physiology and Biophysics Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1085/jgp.201010593DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3105519PMC
June 2011

We choose to go to the membrane.

Proc Natl Acad Sci U S A 2011 Jun 13;108(25):10027-8. Epub 2011 Jun 13.

Department of Biochemistry, Howard Hughes Medical Institute, Brandeis University, Waltham, MA 02454, USA.

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http://dx.doi.org/10.1073/pnas.1107322108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3121863PMC
June 2011

Structure of a slow CLC Cl⁻/H+ antiporter from a cyanobacterium.

Biochemistry 2011 Feb 11;50(5):788-94. Epub 2011 Jan 11.

Department of Biochemistry, Howard Hughes Medical Institute, Brandeis University, Waltham, Massachusetts 02454, United States.

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http://dx.doi.org/10.1021/bi1019258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3164822PMC
February 2011

Design, function and structure of a monomeric ClC transporter.

Nature 2010 Dec 3;468(7325):844-7. Epub 2010 Nov 3.

Department of Biochemistry, Howard Hughes Medical Institute, Brandeis University, Waltham, Massachusetts 02454, USA.

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http://dx.doi.org/10.1038/nature09556DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3057488PMC
December 2010

Distinct biochemical signatures characterize peripherin isoform expression in both traumatic neuronal injury and motor neuron disease.

J Neurochem 2010 Aug 1;114(4):1177-92. Epub 2010 Jun 1.

Department of Laboratory Medicine and Pathobiology, The University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1111/j.1471-4159.2010.06846.xDOI Listing
August 2010

Amyotrophic lateral sclerosis is a non-amyloid disease in which extensive misfolding of SOD1 is unique to the familial form.

Acta Neuropathol 2010 Mar 29;119(3):335-44. Epub 2010 Jan 29.

Department of Medical Biophysics, Ontario Cancer Institute, University of Toronto, and Department of Laboratory Medicine and Pathobiology, Toronto General Hospital, TMDT 4-305, 101 College Street, Toronto, ON, M5G 1L7, Canada.

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http://dx.doi.org/10.1007/s00401-010-0646-5DOI Listing
March 2010

Relaxin-3 and receptors in the human and rhesus brain and reproductive tissues.

Regul Pept 2010 Jan;159(1-3):44-53

Division of Stem Cell and Developmental Biology, Ontario Cancer Institute, University Health Network (UHN), Toronto, Canada.

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http://dx.doi.org/10.1016/j.regpep.2009.09.007DOI Listing
January 2010

Structure and electrostatic property of cytoplasmic domain of ZntB transporter.

Protein Sci 2009 Oct;18(10):2043-52

Midwest Center for Structural Genomics and Structural Biology Center, Argonne, Illinois 60439, USA.

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http://dx.doi.org/10.1002/pro.215DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2786968PMC
October 2009

Lack of evidence of monomer/misfolded superoxide dismutase-1 in sporadic amyotrophic lateral sclerosis.

Ann Neurol 2009 Jul;66(1):75-80

Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1002/ana.21704DOI Listing
July 2009

Long-pore electrostatics in inward-rectifier potassium channels.

J Gen Physiol 2008 Dec 10;132(6):613-32. Epub 2008 Nov 10.

Program in Physiology, Biophysics and Systems Biology, Weill Graduate School of Medical Sciences, Cornell University, New York, NY 10065, USA.

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http://www.jgp.org/lookup/doi/10.1085/jgp.200810068
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http://dx.doi.org/10.1085/jgp.200810068DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2585864PMC
December 2008

Genetic studies of GRN and IFT74 in amyotrophic lateral sclerosis.

Neurobiol Aging 2008 Aug 23;29(8):1279-82. Epub 2007 Mar 23.

Centre for Research in Neurodegenerative Diseases, Tanz Neuroscience Building, University of Toronto, 6 Queen's Park Crescent West, Toronto, Ontario, Canada M5S 3H2.

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http://dx.doi.org/10.1016/j.neurobiolaging.2007.02.022DOI Listing
August 2008

A novel peripherin isoform generated by alternative translation is required for normal filament network formation.

J Neurochem 2008 Mar 17;104(6):1663-73. Epub 2008 Jan 17.

Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1111/j.1471-4159.2007.05198.xDOI Listing
March 2008

Evidence that TDP-43 is not the major ubiquitinated target within the pathological inclusions of amyotrophic lateral sclerosis.

J Neuropathol Exp Neurol 2007 Dec;66(12):1147-53

Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Ontario, Canada.

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http://dx.doi.org/10.1097/nen.0b013e31815c5eddDOI Listing
December 2007

An immunological epitope selective for pathological monomer-misfolded SOD1 in ALS.

Nat Med 2007 Jun 7;13(6):754-9. Epub 2007 May 7.

Department of Biochemistry, University of Toronto and Ontario Cancer Institute, 101 College Street, Toronto, Ontario M5G 1L7, Canada.

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http://www.nature.com/articles/nm1559
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http://dx.doi.org/10.1038/nm1559DOI Listing
June 2007

Lack of TDP-43 abnormalities in mutant SOD1 transgenic mice shows disparity with ALS.

Neurosci Lett 2007 Jun 8;420(2):128-32. Epub 2007 Apr 8.

Centre for Research in Neurodegenerative Diseases, Department of Laboratory, Medicine and Pathobiology, University of Toronto, Toronto, Canada M5S 3H2.

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http://dx.doi.org/10.1016/j.neulet.2007.03.066DOI Listing
June 2007

Neuronal intermediate filaments and ALS: a new look at an old question.

Biochim Biophys Acta 2006 Nov-Dec;1762(11-12):1001-12. Epub 2006 Sep 12.

Department of Laboratory Medicine and Pathobiology, Centre for Research in Neurodegenerative Diseases, University of Toronto, Tanz Neuroscience Building, 6, Queen's Park Crescent West, Toronto, ON, Canada M5S 3H2.

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http://linkinghub.elsevier.com/retrieve/pii/S092544390600176
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http://dx.doi.org/10.1016/j.bbadis.2006.09.003DOI Listing
January 2007

Defective axonal transport of neurofilament proteins in neurons overexpressing peripherin.

J Neurochem 2006 Aug 19;98(3):926-38. Epub 2006 Jun 19.

Research Centre of Centre Hospitalier Universitaire de Québec, Department of Anatomy and Physiology of Laval University, Quebec, Canada.

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http://dx.doi.org/10.1111/j.1471-4159.2006.03932.xDOI Listing
August 2006

The role of RNA and RNA processing in neurodegeneration.

J Neurosci 2005 Nov;25(45):10372-5

Medical Research Council Centre for Neurodegeneration Research, Department of Neurology, Institute of Psychiatry, King's College London, SE5 8AF, United Kingdom.

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http://www.jneurosci.org/content/25/45/10372.full.pdf
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http://www.jneurosci.org/cgi/doi/10.1523/JNEUROSCI.3453-05.2
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http://dx.doi.org/10.1523/JNEUROSCI.3453-05.2005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6725807PMC
November 2005

One channel: open and closed.

Structure 2005 Oct;13(10):1398-400

Department of Physiology and Biophysics, Weill Medical College of Cornell University, New York, New York 10021, USA.

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http://dx.doi.org/10.1016/j.str.2005.09.004DOI Listing
October 2005

Carboxy-terminal determinants of conductance in inward-rectifier K channels.

J Gen Physiol 2004 Dec;124(6):729-39

Department of Physiology and Biophysics, Weill Medical College of Cornell University, 1300 York Ave., New York, NY 10021, USA.

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http://dx.doi.org/10.1085/jgp.200409166DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2234023PMC
December 2004

A neurotoxic peripherin splice variant in a mouse model of ALS.

J Cell Biol 2003 Mar;160(6):939-49

Centre for Research in Neurosciences, Research Institute of the McGill University Health Centre, McGill University, Montreal, Quebec, H3G 1A4, Canada.

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http://dx.doi.org/10.1083/jcb.200205027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2173778PMC
March 2003

Pathways to motor neuron degeneration in transgenic mouse models.

Biochimie 2002 Nov;84(11):1151-60

Centre for Research in Neurosciences, McGill University, Research Institute of the McGill University Health Centre, 1650 Cedar Avenue, Montréal, Québec, Canada H3G 1A4.

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http://dx.doi.org/10.1016/s0300-9084(02)00025-1DOI Listing
November 2002