Jane Fridlyand

Jane Fridlyand

UNVERIFIED PROFILE

Are you Jane Fridlyand?   Register this Author

Register author
Jane Fridlyand

Jane Fridlyand

Publications by authors named "Jane Fridlyand"

Are you Jane Fridlyand?   Register this Author

53Publications

837Reads

39Profile Views

Considerations for the successful co-development of targeted cancer therapies and companion diagnostics.

Nat Rev Drug Discov 2013 10 6;12(10):743-55. Epub 2013 Sep 6.

Genentech, 1 DNA Way, MS 441b, South San Francisco, California 94080, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nrd4101DOI Listing
October 2013

Analysis of tumor burden versus progression-free survival for Phase II decision making.

Contemp Clin Trials 2011 May 23;32(3):446-52. Epub 2011 Jan 23.

Genentech, South San Francisco, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cct.2011.01.010DOI Listing
May 2011

Statistical techniques to construct assays for identifying likely responders to a treatment under evaluation from cell line genomic data.

BMC Cancer 2010 Oct 27;10:586. Epub 2010 Oct 27.

Biometric Research Branch - Department of Cancer Treatment and Diagnosis, National Cancer Institute, National Institutes of Health. Rockville, MD 20852, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-2407-10-586DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2984428PMC
October 2010

Reversing HOXA9 oncogene activation by PI3K inhibition: epigenetic mechanism and prognostic significance in human glioblastoma.

Cancer Res 2010 Jan 12;70(2):453-62. Epub 2010 Jan 12.

The Brain Tumor Research Center, Department of Neurological Surgery, University of California-San Francisco, San Francisco, California 94158-9001, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/0008-5472.CAN-09-2189DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2849935PMC
January 2010

High-resolution genomic and expression analyses of copy number alterations in breast tumors.

Genes Chromosomes Cancer 2008 Jun;47(6):530-42

Department of Bioinformatics, Genentech, Inc., South San Francisco, CA 94080, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/gcc.20558DOI Listing
June 2008

Improving melanoma classification by integrating genetic and morphologic features.

PLoS Med 2008 Jun;5(6):e120

Department of Dermatology, University of California San Francisco, San Francisco, California, United States of America.

View Article

Download full-text PDF

Source
https://dx.plos.org/10.1371/journal.pmed.0050120
Publisher Site
http://dx.doi.org/10.1371/journal.pmed.0050120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2408611PMC
June 2008

FBXW7 and DNA copy number instability.

Breast Cancer Res Treat 2008 May 23;109(1):47-54. Epub 2007 Jun 23.

Cancer Research Institute, University of California San Francisco, Box 0808, San Francisco, CA 94143-0808, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s10549-007-9623-7DOI Listing
May 2008

Integration of genomic analysis and in vivo transfection to identify sprouty 2 as a candidate tumor suppressor in liver cancer.

Hepatology 2008 Apr;47(4):1200-10

Department of Biopharmaceutical Sciences, University of California, San Francisco, CA 94143, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/hep.22169DOI Listing
April 2008

Genome position and gene amplification.

Genome Biol 2007 ;8(6):R120

Cancer Research Institute, University of California San Francisco, San Francisco, CA 94143-0808, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/gb-2007-8-6-r120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2394771PMC
February 2008

Evaluation of whole genome amplification protocols for array and oligonucleotide CGH.

Diagn Mol Pathol 2007 Dec;16(4):198-206

Department of Urology University of California at San Francisco Comprehensive Cancer Center, San Francisco, CA, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/PDM.0b013e3180f62ad5DOI Listing
December 2007

Lack of germ-line promoter methylation in BRCA1-negative families with familial breast cancer.

Genet Test 2006 ;10(4):281-4

Department of Neurological Surgery, UCSF Comprehensive Cancer Center, San Francisco, California 9443-0875, USA.

View Article

Download full-text PDF

Source
http://www.liebertpub.com/doi/10.1089/gte.2006.10.281
Publisher Site
http://dx.doi.org/10.1089/gte.2006.10.281DOI Listing
April 2007

Phase I study of intraventricular administration of rituximab in patients with recurrent CNS and intraocular lymphoma.

J Clin Oncol 2007 Apr 20;25(11):1350-6. Epub 2007 Feb 20.

Division of Hematology/Oncology, and the Department of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, CA 94143, USA.

View Article

Download full-text PDF

Source
http://ascopubs.org/doi/10.1200/JCO.2006.09.7311
Publisher Site
http://dx.doi.org/10.1200/JCO.2006.09.7311DOI Listing
April 2007

Chromosomal aberrations in angioimmunoblastic T-cell lymphoma and peripheral T-cell lymphoma unspecified: A matrix-based CGH approach.

Genes Chromosomes Cancer 2007 Jan;46(1):37-44

Department of Pathology, German Consultation and Reference Center for Lymphomas, University Clinic Schleswig-Holstein, Campus Luebeck, Luebeck, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/gcc.20386DOI Listing
January 2007

Deletion of chromosome 11q predicts response to anthracycline-based chemotherapy in early breast cancer.

Cancer Res 2007 Jan;67(2):818-26

Division of Oncology, Center for Applied Medical Research, University of Navarra, Pamplona, and Department of Hematology and Medical Oncology, Hospital Clinico, University of Valencia, Spain.

View Article

Download full-text PDF

Source
http://cancerres.aacrjournals.org/cgi/doi/10.1158/0008-5472.
Publisher Site
http://dx.doi.org/10.1158/0008-5472.CAN-06-3307DOI Listing
January 2007

Chromosomal instability in microsatellite-unstable and stable colon cancer.

Clin Cancer Res 2006 Nov;12(21):6379-85

Comprehensive Cancer Center, Department of Medicine, University of California San Francisco, San Francisco, California 94143-0808, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-06-1248DOI Listing
November 2006

Tumor suppressor p16INK4A regulates polycomb-mediated DNA hypermethylation in human mammary epithelial cells.

J Biol Chem 2006 Aug 9;281(34):24790-802. Epub 2006 Jun 9.

Comprehensive Cancer Center, University of California, San Francisco, San Francisco, California 94143-0511, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M604175200DOI Listing
August 2006

A comparison study: applying segmentation to array CGH data for downstream analyses.

Bioinformatics 2005 Nov 13;21(22):4084-91. Epub 2005 Sep 13.

Center for Biological Sequence Analysis, Department of Biotechnology, Technical University of Denmark, Kgs. Lyngby.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bioinformatics/bti677DOI Listing
November 2005

Distinct sets of genetic alterations in melanoma.

N Engl J Med 2005 Nov;353(20):2135-47

Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA 94143-0808, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1056/NEJMoa050092DOI Listing
November 2005

Bladder cancer stage and outcome by array-based comparative genomic hybridization.

Clin Cancer Res 2005 Oct;11(19 Pt 1):7012-22

Department of Laboratory Medicine, University of California San Francisco, San Francisco, California 94143-0808, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1158/1078-0432.CCR-05-0177DOI Listing
October 2005

Therapy-induced malignant neoplasms in Nf1 mutant mice.

Cancer Cell 2005 Oct;8(4):337-48

Department of Pediatrics, University of California, San Francisco, San Francisco, California 94143, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccr.2005.08.011DOI Listing
October 2005

Rare amplicons implicate frequent deregulation of cell fate specification pathways in oral squamous cell carcinoma.

Oncogene 2005 Jun;24(26):4232-42

Cancer Research Institute, University of California San Francisco, Box 0808, San Francisco, CA 94143-0808, USA.

View Article

Download full-text PDF

Source
http://www.nature.com/articles/1208601
Publisher Site
http://dx.doi.org/10.1038/sj.onc.1208601DOI Listing
June 2005

Epigenome analyses using BAC microarrays identify evolutionary conservation of tissue-specific methylation of SHANK3.

Nat Genet 2005 Jun 15;37(6):645-51. Epub 2005 May 15.

The Brain Tumor Research Center, Department of Neurological Surgery and the Biomedical Sciences Program, University of California San Francisco, San Franciso, California 94143, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/ng1563DOI Listing
June 2005

High-resolution analysis of DNA copy number alterations in colorectal cancer by array-based comparative genomic hybridization.

Carcinogenesis 2004 Aug 4;25(8):1345-57. Epub 2004 Mar 4.

Second Department of Surgery, Showa University School of Medicine, Tokyo, Japan.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/carcin/bgh134DOI Listing
August 2004

Mechanisms of cell-cycle arrest in Spitz nevi with constitutive activation of the MAP-kinase pathway.

Am J Pathol 2004 May;164(5):1783-7

Department of Dermatology, University of California, San Francisco, California 94143, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1615645PMC
http://dx.doi.org/10.1016/S0002-9440(10)63736-4DOI Listing
May 2004

Oncogene expression and genetic background influence the frequency of DNA copy number abnormalities in mouse pancreatic islet cell carcinomas.

Cancer Res 2004 Apr;64(7):2406-10

Department of Biochemistry, University of California at San Francisco Diabetes and Comprehensive Cancer Center, University of California at San Francisco, San Francisco, California 94143, USA.

View Article

Download full-text PDF

Source
April 2004

Determinants of BRAF mutations in primary melanomas.

J Natl Cancer Inst 2003 Dec;95(24):1878-90

Department of Dermatology, University of California, San Francisco, San Francisco, CA 94115, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jnci/djg123DOI Listing
December 2003

Differentiation of lobular versus ductal breast carcinomas by expression microarray analysis.

Cancer Res 2003 Nov;63(21):7167-75

Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA 94143-0808, USA.

View Article

Download full-text PDF

Source
November 2003

Shaping of tumor and drug-resistant genomes by instability and selection.

Oncogene 2003 Jul;22(28):4370-9

Cancer Research Institute, University of California San Francisco, San Francisco, CA 94143-0808, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/sj.onc.1206482DOI Listing
July 2003

Bagging to improve the accuracy of a clustering procedure.

Bioinformatics 2003 Jun;19(9):1090-9

Division of Biostatistics, School of Public Health, University of California, Berkeley, 140 Earl Warren Hall, 7360, Berkeley, CA 94720-7360, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/bioinformatics/btg038DOI Listing
June 2003

Multiple genetic loci modify susceptibility to plasmacytoma-related morbidity in E(mu)-v-abl transgenic mice.

Proc Natl Acad Sci U S A 2002 Aug 30;99(17):11299-304. Epub 2002 Jul 30.

The Walter and Eliza Hall Institute of Medical Research, Post Office, Royal Melbourne Hospital, Victoria 3050, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.162566999DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC123251PMC
August 2002

A prediction-based resampling method for estimating the number of clusters in a dataset.

Genome Biol 2002 Jun 25;3(7):RESEARCH0036. Epub 2002 Jun 25.

Division of Biostatistics, School of Public Health, University of California Berkeley, 140 Earl Warren Hall, Berkeley, CA 94720-7360, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC126241PMC
http://dx.doi.org/10.1186/gb-2002-3-7-research0036DOI Listing
June 2002