Jane F Ferguson

Jane F Ferguson

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Jane F Ferguson

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The Gut Microbiome and Response to Cardiovascular Drugs.

Circ Genom Precis Med 2019 Aug 28. Epub 2019 Aug 28.

Vanderbilt University Medical Center, Nashville, TN.

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http://dx.doi.org/10.1161/CIRCGEN.119.002314DOI Listing
August 2019

Omega-3 polyunsaturated fatty acids attenuate inflammatory activation and alter differentiation in human adipocytes.

J Nutr Biochem 2019 Feb 11;64:45-49. Epub 2018 Oct 11.

Division of Endocrinology and Diabetes, Children's Hospital of Philadelphia, Philadelphia, PA, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S09552863183029
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http://dx.doi.org/10.1016/j.jnutbio.2018.09.027DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363876PMC
February 2019

Development of the Gut Microbiome in Children, and Lifetime Implications for Obesity and Cardiometabolic Disease.

Children (Basel) 2018 Nov 27;5(12). Epub 2018 Nov 27.

Division of Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, TN 37232, USA.

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http://dx.doi.org/10.3390/children5120160DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6306821PMC
November 2018

Tissue-Specific Differential Expression of Novel Genes and Long Intergenic Noncoding RNAs in Humans With Extreme Response to Evoked Endotoxemia.

Circ Genom Precis Med 2018 11;11(11):e001907

Cardiology Division, Department of Medicine, Columbia University Medical Center, New York, NY (C.X., Y.G., J.S., X.Z., Y.W., Y.D.L., H.Z., M.P.R.).

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http://dx.doi.org/10.1161/CIRCGEN.117.001907DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6309423PMC
November 2018

Acute effects of insulin on circulating natriuretic peptide levels in humans.

PLoS One 2018 14;13(5):e0196869. Epub 2018 May 14.

Vanderbilt Translational and Clinical Cardiovascular Research Center, Vanderbilt University School of Medicine, Nashville, Tennessee, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0196869PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5951576PMC
July 2018

Expression of Calgranulin Genes S100A8, S100A9 and S100A12 Is Modulated by n-3 PUFA during Inflammation in Adipose Tissue and Mononuclear Cells.

PLoS One 2017 26;12(1):e0169614. Epub 2017 Jan 26.

Division of Cardiovascular Medicine, and Vanderbilt Translational and Clinical Cardiovascular Research Center (VTRACC), Vanderbilt University Medical Center, Nashville, Tennessee, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0169614PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5268473PMC
August 2017

Synergistic Modulation of Inflammatory but not Metabolic Effects of High-Fat Feeding by CCR2 and CX3CR1.

Obesity (Silver Spring) 2017 Aug 26;25(8):1410-1420. Epub 2017 Jun 26.

Division of Cardiology, Department of Medicine, Columbia University Medical Center, New York, New York, USA.

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http://dx.doi.org/10.1002/oby.21900DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5610963PMC
August 2017

Loss of Cardioprotective Effects at the Locus as a Result of Gene-Smoking Interactions.

Circulation 2017 Jun 1;135(24):2336-2353. Epub 2017 May 1.

From Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia (D.S., W.Z.); Center for Non-Communicable Diseases, Karachi, Pakistan (D.S., A.R., P.M.F., PROMIS); Department of Public Health and Primary Care, University of Cambridge, United Kingdom (R.Y., W.K.H., EPIC-CVD); Department of Cardiovascular Sciences, University of Leicester, United Kingdom (C.P.N., N.J.S.); Cardiology Division, Department of Medicine, Vanderbilt University, Nashville, TN (J.F.F., K.O.); Division of Cardiovascular Medicine, Radcliffe Department of Medicine & Wellcome Trust Centre for Human Genetics, University of Oxford, United Kingdom (A.G., M.F.); The Charles Bronfman Institute of Personalized Medicine, Icahn School of Medicine at Mount Sinai, New York, NY (R.D.); Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY (R.D.); Ruddy Canadian Cardiovascular Genetics Centre, University of Ottawa Heart Institute, Canada (A.F.R.S., R.M.); Institute for Genetic Medicine and Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles (J.H., H.A.); Department of Epidemiology and Biostatistics, Imperial College London, United Kingdom (W.Z., J.C.C., J.K.); Department of Cardiology, Ealing Hospital NHS Trust, Middlesex, United Kingdom (W.Z., J.C.C.); Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden (R.J.S.); Helsinki University Central Hospital HUCH Heart and Lung Center, Helsinki, Uusimaa, Finland (J.S.); Cardiology Division, Department of Medicine and the Irving Institute for Clinical and Translational Research, Columbia University Medical Center, New York, NY (R.C.B., M.P.R.); William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, United Kingdom (S.K., E.M., P.D.); Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands (S.S., A.D.); Department of Dietetics-Nutrition, Harokopio University, Athens, Greece (E.M., G.D.); National Institute for Health and Welfare, Helsinki, Finland (K.K., A.J., V.S., K.K., M.P.); MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge School of Clinical Medicine, Cambridge Biomedical Campus, United Kingdom (J.H.Z., R.S.); INSERM, UMRS1138, Centre de Recherche des Cordeliers, Paris, France (D.G., N.W.); Division of Cardiology, Department of Medicine, Duke University Medical Center, Durham, NC (S.H.S.); Icelandic Heart Association, Kopavogur, Iceland (A.V.S., V.G.); Medical Research Institute, Ninewells Hospital and Medical School, University of Dundee, United Kingdom (N.v.Z., C.N.A.P.); Center for Genomics and Personalized Medicine Research, Wake Forest School of Medicine, Winston-Salem, NC (A.J.C., D.W.B.); Institut für Integrative und Experimentelle Genomik, Universität zu Lübeck, Germany (C.W., J.E.); DZHK (German Research Center for Cardiovascular Research) partner site Hamburg-Lübeck-Kiel, Germany (C.W., J.E.); Deutsches Herzzentrum München, Technische Universität München, Germany (T.K., L.Z., H.S.); Klinikum rechts der Isar, München, Germany (T.K.); DZHK (German Centre for Cardiovascular Research), Partner Site Munich Heart Alliance, Germany (L.Z., H.S.); Department of Genetics, Washington University School of Medicine, St. Louis, MO (M.A.P., M.F.F.); Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital and Harvard Medical School, Boston (A.G.); Program in Medical and Population Genetics, Broad Institute of Harvard and MIT, Cambridge, MA (A.G.); Department of Medical Sciences, Cardiovascular Epidemiology, Uppsala University, Sweden (L.L.); Department of Medical Epidemiology and Biostatistics, Karolinska Institutet, Stockholm, Sweden (N.L.P.); Department of Biostatistics Boston University School of Public Health Framingham Heart Study, MA (C.C.W.); Faculty of Medicine, University of Iceland, Reykjavik (A.V.S., V.G.); University of Helsinki, Institute for Molecular Medicine, Finland (FIMM) (A.J., M.P.); Department of Medicine, Mannheim Medical Faculty, Heidelberg University, Germany (M.E.K.); Leeds Institute of Genetics, Health and Therapeutics, University of Leeds, Leeds, United Kingdom (A.S.H.); Synlab Academy, Synlab Services GmbH, Mannheim, Germany and Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Austria (W.M.); National Heart, Lung, and Blood Institute and the Framingham Heart Study, National Institutes of Health, Bethesda, MD (C.O'D.); Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory, Uppsala University, Sweden (E.I.); Department of Medicine, Division of Cardiovascular Medicine, Stanford University School of Medicine, CA (E.I.); Division of Cardiovascular Epidemiology, Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden (U.D.F.); Lebanese American University, School of Medicine, Beirut (P.Z.); Department of Health Sciences, University of Leicester, United Kingdom (J.R.T.); Imperial College Healthcare NHS Trust, London, United Kingdom (J.C.C., J.K.); Cardiovascular Science, National Heart and Lung Institute, Imperial College London, United Kingdom (J.K.); Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah, Saudi Arabia (P.D.); deCODE Genetics, Sturlugata 8, IS-101 Reykjavik, Iceland (G.T., K.S.); University of Iceland, School of Medicine, Reykjavik, Iceland (G.T., K.S.); Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge (S.K.); Cardiovascular Research Center, Massachusetts General Hospital, Boston (S.K.); Center for Human Genetic Research, Massachusetts General Hospital, Boston (S.K.); Department of Medicine, Harvard Medical School, Boston, MA (S.K.); Department of Genetics, University of Pennsylvania, Philadelphia (D.J.R.); and Division of Translational Medicine and Human Genetics, Department of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia (S.T.N., D.J.R.).

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http://dx.doi.org/10.1161/CIRCULATIONAHA.116.022069DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5612779PMC
June 2017

Branched-Chain Amino Acids and Cardiovascular Disease: Does Diet Matter?

Clin Chem 2016 Apr 16;62(4):545-7. Epub 2016 Feb 16.

Division of Cardiovascular Medicine and Vanderbilt Translational and Clinical Cardiovascular Research Center (VTRACC), Vanderbilt University Medical Center, Nashville, TN.

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http://dx.doi.org/10.1373/clinchem.2016.254318DOI Listing
April 2016

Adipose tissue RNASeq reveals novel gene-nutrient interactions following n-3 PUFA supplementation and evoked inflammation in humans.

J Nutr Biochem 2016 Apr 11;30:126-32. Epub 2016 Jan 11.

Cardiovascular Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.

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http://dx.doi.org/10.1016/j.jnutbio.2015.12.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808243PMC
April 2016

Bioactive products formed in humans from fish oils.

J Lipid Res 2015 Sep 15;56(9):1808-20. Epub 2015 Jul 15.

Institute for Translational Medicine and Therapeutics (ITMAT), Smilow Center for Translational Research, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104.

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http://dx.doi.org/10.1194/jlr.M060392DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4548785PMC
September 2015

Human experimental endotoxemia in modeling the pathophysiology, genomics, and therapeutics of innate immunity in complex cardiometabolic diseases.

Arterioscler Thromb Vasc Biol 2015 Mar 30;35(3):525-34. Epub 2014 Dec 30.

From the Cardiovascular Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia (P.N.P., R.Y.S., M.P.R.); and Division of Cardiovascular Medicine, Vanderbilt University School of Medicine, Nashville, TN (J.F.F.).

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https://www.ahajournals.org/doi/10.1161/ATVBAHA.114.304455
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http://dx.doi.org/10.1161/ATVBAHA.114.304455DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4344396PMC
March 2015

Tissue-specific RNA-Seq in human evoked inflammation identifies blood and adipose LincRNA signatures of cardiometabolic diseases.

Arterioscler Thromb Vasc Biol 2014 Apr 6;34(4):902-12. Epub 2014 Feb 6.

From the Departments of Biostatistics and Epidemiology and Biology, Cardiovascular Institute, Perelman School of Medicine and School of Arts and Science at the University of Pennsylvania, Philadelphia.

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http://dx.doi.org/10.1161/ATVBAHA.113.303123DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3966947PMC
April 2014

Evaluating the impact of sequencing depth on transcriptome profiling in human adipose.

PLoS One 2013 24;8(6):e66883. Epub 2013 Jun 24.

Department of Biostatistics and Epidemiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, United States of America.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0066883PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3691247PMC
February 2014

PennSeq: accurate isoform-specific gene expression quantification in RNA-Seq by modeling non-uniform read distribution.

Nucleic Acids Res 2014 Feb 20;42(3):e20. Epub 2013 Dec 20.

Department of Biostatistics and Epidemiology, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA and Cardiovascular Institute, University of Pennsylvania Perelman School of Medicine, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1093/nar/gkt1304DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919567PMC
February 2014

Mixed modeling of meta-analysis P-values (MixMAP) suggests multiple novel gene loci for low density lipoprotein cholesterol.

PLoS One 2013 6;8(2):e54812. Epub 2013 Feb 6.

Division of Biostatistics, School of Public Health and Health Sciences at the University of Massachusetts, Amherst, MA, USA.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0054812PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3566142PMC
December 2013

Improvement in insulin sensitivity after human islet transplantation for type 1 diabetes.

J Clin Endocrinol Metab 2013 Nov 1;98(11):E1780-5. Epub 2013 Oct 1.

MD, MS, Perelman School of Medicine at the University of Pennsylvania, 12-134 Smilow Center for Translational Research, 3400 Civic Center Boulevard, Philadelphia, Pennsylvania 19104.

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http://dx.doi.org/10.1210/jc.2013-1764DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816271PMC
November 2013

Meat-loving microbes: do steak-eating bacteria promote atherosclerosis?

Authors:
Jane F Ferguson

Circ Cardiovasc Genet 2013 Jun;6(3):308-9

Cardiovascular Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1161/CIRCGENETICS.113.000213DOI Listing
June 2013

Race and gender variation in response to evoked inflammation.

J Transl Med 2013 Mar 12;11:63. Epub 2013 Mar 12.

Cardiovascular Institute, Perelman School of Medicine, at the University of Pennsylvania, 11-136 Smilow Center for Translational Research, Building 421, 3400 Civic Center Boulevard, Philadelphia, PA 19104, USA.

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https://translational-medicine.biomedcentral.com/articles/10
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http://dx.doi.org/10.1186/1479-5876-11-63DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3636014PMC
March 2013

Increasing power: multivariate analysis of metabolic networks reveals novel atherosclerosis loci.

Authors:
Jane F Ferguson

Circ Cardiovasc Genet 2012 Oct;5(5):595-6

Perelman School of Medicine, University of Pennsylvania, 11–170 Translational Research Center, 3400 Civic Center Blvd, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1161/CIRCGENETICS.112.964882DOI Listing
October 2012

Docosahexaenoic acid attenuates macrophage-induced inflammation and improves insulin sensitivity in adipocytes-specific differential effects between LC n-3 PUFA.

J Nutr Biochem 2012 Sep 1;23(9):1192-200. Epub 2011 Dec 1.

Nutrigenomics Research Group, UCD Conway Institute, & UCD Institute of Food and Health, University College Dublin, Dublin 4, Ireland.

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http://dx.doi.org/10.1016/j.jnutbio.2011.06.014DOI Listing
September 2012

Peroxisome Proliferator-Activated Receptor-α Agonism With Fenofibrate Does Not Suppress Inflammatory Responses to Evoked Endotoxemia.

J Am Heart Assoc 2012 Aug 24;1(4):e002923. Epub 2012 Aug 24.

Cardiovascular Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA (C.K.M., J.F.F., J.T.-M., S.K., R.Y.S., P.N.P., M.H.U.U., N.N.M., M.P.R.).

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https://www.ahajournals.org/doi/10.1161/JAHA.112.002923
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http://dx.doi.org/10.1161/JAHA.112.002923DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487364PMC
August 2012

Omics gets personal: integrative profiling of health and disease.

Authors:
Jane F Ferguson

Circ Cardiovasc Genet 2012 Jun;5(3):381-2

Perelman School of Medicine, University of Pennsylvania, Philadelphia, 19104, USA.

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http://dx.doi.org/10.1161/CIRCGENETICS.112.963801DOI Listing
June 2012

Genetic determinants of the ankle-brachial index: a meta-analysis of a cardiovascular candidate gene 50K SNP panel in the candidate gene association resource (CARe) consortium.

Atherosclerosis 2012 May 2;222(1):138-47. Epub 2012 Feb 2.

University of California San Diego, Department of Family and Preventive Medicine, Division of Preventive Medicine, La Jolla, CA, USA.

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http://dx.doi.org/10.1016/j.atherosclerosis.2012.01.039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3596171PMC
May 2012

Top advances in functional genomics and translational biology for 2011.

Circ Cardiovasc Genet 2012 Feb;5(1):143-5

Early Career Committee of the American Heart Association Functional Genomics and Translational Biology Council.

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http://dx.doi.org/10.1161/CIRCGENETICS.111.962621DOI Listing
February 2012

Fractalkine is a novel human adipochemokine associated with type 2 diabetes.

Diabetes 2011 May;60(5):1512-8

Division of Pediatric Endocrinology, Children's Hospital of Philadelphia, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.2337/db10-0956DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3292325PMC
May 2011

The novel atherosclerosis locus at 10q11 regulates plasma CXCL12 levels.

Eur Heart J 2011 Apr 17;32(8):963-71. Epub 2011 Mar 17.

Penn Cardiovascular Institute, University of Pennsylvania School of Medicine, Penn Tower, 6th Floor, 3400 Civic Center Blvd, Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1093/eurheartj/ehr091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3076669PMC
April 2011

Additive effect of polymorphisms in the IL-6, LTA, and TNF-{alpha} genes and plasma fatty acid level modulate risk for the metabolic syndrome and its components.

J Clin Endocrinol Metab 2010 Mar 15;95(3):1386-94. Epub 2010 Jan 15.

Nutrigenomics Research Group, University College Dublin School of Public Health and Population Science, University College Dublin Conway Institute, University College Dublin, Belfield, Dublin 4, Ireland.

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https://academic.oup.com/jcem/article-lookup/doi/10.1210/jc.
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http://dx.doi.org/10.1210/jc.2009-1081DOI Listing
March 2010

Complement component 3 polymorphisms interact with polyunsaturated fatty acids to modulate risk of metabolic syndrome.

Am J Clin Nutr 2009 Dec 14;90(6):1665-73. Epub 2009 Oct 14.

Nutrigenomics Research Group, UCD School of Public Health and Population Science, UCD Conway Institute, University College Dublin, Dublin, Ireland.

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https://academic.oup.com/ajcn/article/90/6/1665/4598129
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http://dx.doi.org/10.3945/ajcn.2009.28101DOI Listing
December 2009