Jane Apperley

Jane Apperley

UNVERIFIED PROFILE

Are you Jane Apperley?   Register this Author

Register author
Jane Apperley

Jane Apperley

Publications by authors named "Jane Apperley"

Are you Jane Apperley?   Register this Author

100Publications

3530Reads

10Profile Views

Blast crisis of chronic myeloid leukemia with plasmacytoid dendritic cell phenotype associated with a rare fusion transcript, e13a3 BCR-ABL1.

Leuk Lymphoma 2019 Dec 11;60(12):3090-3091. Epub 2019 Jun 11.

Clinical Haematology, Hammersmith Hospital, Imperial College NHS Trust, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/10428194.2019.1622101DOI Listing
December 2019

Prolonged treatment free remission in chronic myeloid leukemia patients with previous BCR-ABL1 kinase domain mutations.

Haematologica 2019 Sep 19. Epub 2019 Sep 19.

Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3324/haematol.2019.234179DOI Listing
September 2019

The influence of salivary amylase on total amylase elevation in CML patients treated with TKI therapy: a case series of 3 patients.

Leuk Lymphoma 2019 Jun 22:1-2. Epub 2019 Jun 22.

a Department of Haematology, Hammersmith Hospital , Imperial College Healthcare NHS Trust , London , United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1080/10428194.2019.1627536DOI Listing
June 2019

Back to the future: Treatment-free remission and pregnancy in chronic myeloid leukemia.

Eur J Haematol 2019 Feb 29;102(2):197-199. Epub 2018 Nov 29.

Memorial Sloan Kettering Cancer Center, New York City, New York.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/ejh.13192
Publisher Site
http://dx.doi.org/10.1111/ejh.13192DOI Listing
February 2019

The argument for using imatinib in CML.

Hematology Am Soc Hematol Educ Program 2018 11;2018(1):161-167

Department of Clinical Haematology, Hammersmith Hospital, Imperial College Healthcare NHS Trust, London, United Kingdom; and.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/asheducation-2018.1.161DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6246007PMC
November 2018

Protease nexin-1 prevents growth of human B cell lymphoma via inhibition of sonic hedgehog signaling.

Blood Cancer J 2018 02 26;8(2):24. Epub 2018 Feb 26.

Department of Haematology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Hubei, China.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41408-018-0063-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5827524PMC
February 2018

BKV-specific T cells in the treatment of severe refractory haemorrhagic cystitis after HLA-haploidentical haematopoietic cell transplantation.

Eur J Haematol 2017 Jun 1;98(6):632-634. Epub 2017 Mar 1.

Centre for Haematology, Imperial College at Hammersmith Hospital, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1111/ejh.12848DOI Listing
June 2017

Molecular techniques for the personalised management of patients with chronic myeloid leukaemia.

Biomol Detect Quantif 2017 Mar 14;11:4-20. Epub 2017 Feb 14.

Centre for Haematology, Department of Medicine, Imperial College London Hammersmith Hospital, London UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bdq.2017.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348117PMC
March 2017

Epigenome-wide association study of body mass index, and the adverse outcomes of adiposity.

Authors:
Simone Wahl Alexander Drong Benjamin Lehne Marie Loh William R Scott Sonja Kunze Pei-Chien Tsai Janina S Ried Weihua Zhang Youwen Yang Sili Tan Giovanni Fiorito Lude Franke Simonetta Guarrera Silva Kasela Jennifer Kriebel Rebecca C Richmond Marco Adamo Uzma Afzal Mika Ala-Korpela Benedetta Albetti Ole Ammerpohl Jane F Apperley Marian Beekman Pier Alberto Bertazzi S Lucas Black Christine Blancher Marc-Jan Bonder Mario Brosch Maren Carstensen-Kirberg Anton J M de Craen Simon de Lusignan Abbas Dehghan Mohamed Elkalaawy Krista Fischer Oscar H Franco Tom R Gaunt Jochen Hampe Majid Hashemi Aaron Isaacs Andrew Jenkinson Sujeet Jha Norihiro Kato Vittorio Krogh Michael Laffan Christa Meisinger Thomas Meitinger Zuan Yu Mok Valeria Motta Hong Kiat Ng Zacharoula Nikolakopoulou Georgios Nteliopoulos Salvatore Panico Natalia Pervjakova Holger Prokisch Wolfgang Rathmann Michael Roden Federica Rota Michelle Ann Rozario Johanna K Sandling Clemens Schafmayer Katharina Schramm Reiner Siebert P Eline Slagboom Pasi Soininen Lisette Stolk Konstantin Strauch E-Shyong Tai Letizia Tarantini Barbara Thorand Ettje F Tigchelaar Rosario Tumino Andre G Uitterlinden Cornelia van Duijn Joyce B J van Meurs Paolo Vineis Ananda Rajitha Wickremasinghe Cisca Wijmenga Tsun-Po Yang Wei Yuan Alexandra Zhernakova Rachel L Batterham George Davey Smith Panos Deloukas Bastiaan T Heijmans Christian Herder Albert Hofman Cecilia M Lindgren Lili Milani Pim van der Harst Annette Peters Thomas Illig Caroline L Relton Melanie Waldenberger Marjo-Riitta Järvelin Valentina Bollati Richie Soong Tim D Spector James Scott Mark I McCarthy Paul Elliott Jordana T Bell Giuseppe Matullo Christian Gieger Jaspal S Kooner Harald Grallert John C Chambers

Nature 2017 01 21;541(7635):81-86. Epub 2016 Dec 21.

Department of Epidemiology and Biostatistics, MRC-PHE Centre for Environment and Health, School of Public Health, Imperial College London, London W2 1PG, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nature20784DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5570525PMC
January 2017

Cognitive dysfunction after withdrawal of tyrosine kinase inhibitor therapy in chronic myeloid leukaemia.

Am J Hematol 2016 Nov 3;91(11):E480-E481. Epub 2016 Sep 3.

Department of Haematology, The Hammersmith Hospital, Imperial College, London, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ajh.24495DOI Listing
November 2016

Cepheid xpert monitor platform for the confirmation of BCR-ABL1 IS conversion factors for the molecular monitoring of chronic myeloid leukaemia.

Leuk Res 2016 10 13;49:47-50. Epub 2016 Aug 13.

Centre for Haematology, Imperial College London, Du Cane Road, London W12 ONN, UK; Imperial Molecular Pathology, Imperial Healthcare NHS Trust, Hammersmith Hospital, Du Cane Road, London W12 OHS, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.leukres.2016.08.007DOI Listing
October 2016

Matched unrelated donor transplants-State of the art in the 21st century.

Semin Hematol 2016 Oct 25;53(4):221-229. Epub 2016 Jul 25.

Centre for Haematology, Imperial College London, London, United Kingdom. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1053/j.seminhematol.2016.07.002DOI Listing
October 2016

Cost-effectiveness of Tyrosine Kinase Inhibitor Treatment Strategies for Chronic Myeloid Leukemia in Chronic Phase After Generic Entry of Imatinib in the United States.

J Natl Cancer Inst 2016 Jul 4;108(7). Epub 2016 Mar 4.

Affiliations of authors:Department of Health Policy and Management, Johns Hopkins University , Baltimore, MD (WVP); Department of Medicine (RAL) and Departments of Pediatrics and of Public Health Sciences (RMC), University of Chicago, Chicago, IL; Eshelman School of Pharmacy and Gillings School of Global Public Health, Lineberger Comprehensive Cancer Center , and Cecil G. Sheps Center for Health Services Research, University of North Carolina , Chapel Hill, NC (SBD); Department of Haematology, Hammersmith Hospital, Imperial College , London , UK (JFA); Department of Medicine (RH, SS) and Department of Hematology and Oncology (MCM), University of Heidelberg, Mannheim, Germany; Department of Haematology and Oncology, S. Orsola-Malpighi University Hospital (MB), and Department of Hematology, "L. e A. Seragnoli" (GM), University of Bologna , Bologna , Italy ; Department of Haematology and Oncology, University Hospital , Jena , Germany (EE); INSERM Centre d'Investigation Clinique (CIC) 1402, CHU de Poitiers, Poitiers, France (JG, FG); Laboratoire d'Hematologie, Universite Victor Segalen, Bordeaux, Pessac, France (FXM); Department of Internal Medicine, Hematology and Oncology, University Hospital Brno , Brno , Czech Republic (JM); Department of Hematology and Oncology, University Hospital Leipzig , Leipzig , Germany (DN); Barbara Ann Karmanos Cancer Institute, Wayne State University , Detroit, MI (CAS); Department of Medicine, Weill Cornell Medical Center , New York, NY (RTS); Uppsala University , Uppsala , Sweden (BS).

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1093/jnci/djw003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4948567PMC
July 2016

Next-Generation Sequencing-Assisted DNA-Based Digital PCR for a Personalized Approach to the Detection and Quantification of Residual Disease in Chronic Myeloid Leukemia Patients.

J Mol Diagn 2016 Mar 5;18(2):176-89. Epub 2016 Feb 5.

Imperial Molecular Pathology, Imperial Healthcare Trust, Hammersmith Hospital, London, United Kingdom; Centre for Haematology, Faculty of Medicine, Imperial College London, London, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jmoldx.2015.09.005DOI Listing
March 2016

Reprint of: Haploidentical Hematopoietic Stem Cell Transplantation: A Global Overview Comparing Asia, the European Union, and the United States.

Biol Blood Marrow Transplant 2016 Mar;22(3 Suppl):S15-8

Department of Promotion for Blood and Marrow Transplantation, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbmt.2016.01.006DOI Listing
March 2016

Allogeneic transplantation for CML in the TKI era: striking the right balance.

Nat Rev Clin Oncol 2016 Feb 17;13(2):79-91. Epub 2015 Nov 17.

Centre for Haematology, Faculty of Medicine, Imperial College London, Hammersmith Campus, London W12 0NN, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nrclinonc.2015.193DOI Listing
February 2016

Hematologic Malignancies in Pregnancy: Management Guidelines From an International Consensus Meeting.

J Clin Oncol 2016 Feb 30;34(5):501-8. Epub 2015 Nov 30.

Michael Lishner, Meir Medical Center, Kfar Saba, and Tel Aviv University; Irit Avivi, Ichilov Medical Center, Tel Aviv, Israel; Jane F. Apperley, Hammersmith Hospital; Susan Robinson, Guy's and St Thomas' National Health Service Foundation Trust, London; Frank Van den Heuvel, University of Oxford, Oxford, United Kingdom; Andrew M. Evens, Tufts Medical Center, Boston, MA; Monica Fumagalli, University of Milan; Fedro Alessandro Peccatori, European Institute of Oncology, Milan, Italy; Irena Nulman, University of Toronto, and The Hospital for Sick Children, Toronto, Ontario, Canada; Fuat S. Oduncu, University of Munich, Munich, Germany; Kristel Van Calsteren, University Hospital Gasthuisberg; Tineke Vandenbroucke and Frederic Amant, Katholieke Universiteit Leuven; Daan Dierickx, University of Leuven; and Tineke Vandenbroucke, University Hospitals Leuven, Leuven, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1200/JCO.2015.62.4445DOI Listing
February 2016

Haploidentical Hematopoietic Stem Cell Transplantation: A Global Overview Comparing Asia, the European Union, and the United States.

Biol Blood Marrow Transplant 2016 Jan 10;22(1):23-6. Epub 2015 Nov 10.

Department of Promotion for Blood and Marrow Transplantation, Aichi Medical University School of Medicine, Nagakute, Aichi, Japan. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bbmt.2015.11.001DOI Listing
January 2016

The impact of dasatinib on pregnancy outcomes.

Am J Hematol 2015 Dec 12;90(12):1111-5. Epub 2015 Oct 12.

Centre for Haematology, Imperial College, London, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ajh.24186DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5115878PMC
December 2015

Thyroid function abnormalities associated with ponatinib therapy in patients with chronic myeloid leukemia.

Thyroid 2015 Jun 28;25(6):706-7. Epub 2015 Apr 28.

Department of Haematology, Imperial College London, Hammersmith Hospital, London, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1089/thy.2014.0514DOI Listing
June 2015

CML and tyrosine kinase inhibition: the hope becomes reality.

Authors:
Jane F Apperley

Lancet Haematol 2015 May 20;2(5):e176-7. Epub 2015 Apr 20.

Centre for Haematology, Imperial College London, Hammersmith Hospital, London W12 0NN, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S2352-3026(15)00072-1DOI Listing
May 2015

Chronic myeloid leukaemia.

Authors:
Jane F Apperley

Lancet 2015 Apr 5;385(9976):1447-59. Epub 2014 Dec 5.

Department of Haematology, Imperial College London, London, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/S0140-6736(13)62120-0DOI Listing
April 2015

Managing pregnancy in chronic myeloid leukaemia.

Ann Hematol 2015 Apr 27;94 Suppl 2:S167-76. Epub 2015 Mar 27.

Department of Haematology, Imperial College London, Hammersmith Hospital, London, UK,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s00277-015-2317-zDOI Listing
April 2015

PTCH1 expression at diagnosis predicts imatinib failure in chronic myeloid leukaemia patients in chronic phase.

Am J Hematol 2015 Jan 18;90(1):20-6. Epub 2014 Oct 18.

Centre for Haematology, Department of Medicine, Imperial College London, London, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ajh.23857DOI Listing
January 2015

Chronic myeloid leukemia-transplantation in the tyrosine kinase era.

Hematol Oncol Clin North Am 2014 Dec 5;28(6):1037-53. Epub 2014 Oct 5.

Centre for Haematology, Faculty of Medicine, Imperial College London, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK; Department of Clinical Haematology, Imperial College Healthcare NHS Trust, Hammersmith Hospital, Du Cane Road, London W12 0NN, UK. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.hoc.2014.08.002DOI Listing
December 2014

Combined inhibition of p97 and the proteasome causes lethal disruption of the secretory apparatus in multiple myeloma cells.

PLoS One 2013 17;8(9):e74415. Epub 2013 Sep 17.

Gene Regulation and Chromatin Group, MRC Clinical Sciences Centre, Imperial College London, London, United Kingdom ; Centre for Haematology, Department of Medicine, Imperial College London, London, United Kingdom.

View Article

Download full-text PDF

Source
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0074415PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3775786PMC
May 2014

Regulation of advanced therapy medicinal products in Europe and the role of academia.

Cytotherapy 2014 Mar 8;16(3):289-97. Epub 2013 Oct 8.

Department of Haematology, Royal Free Hospital & University College London, United Kingdom. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.jcyt.2013.08.003DOI Listing
March 2014

How I treat leukemia during pregnancy.

Blood 2014 Feb 22;123(7):974-84. Epub 2013 Nov 22.

Department of Haematology, Imperial College London, Hammersmith Hospital, London, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2013-08-283580DOI Listing
February 2014

Rapid initial response of myeloma hyperammonemic encephalopathy to L-ornithine-L-aspartate and dexamethasone therapy.

Leuk Lymphoma 2014 Jan 15;55(1):198-200. Epub 2013 May 15.

Centre for Perioperative Medicine and Critical Care Research, Imperial College Healthcare NHS Trust, Hammersmith Hospital , London , UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3109/10428194.2013.794266DOI Listing
January 2014

Treatment and management of graft-versus-host disease: improving response and survival.

Ther Adv Hematol 2013 Dec;4(6):366-78

Imperial College London at Hammersmith Hospital, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1177/2040620713489842DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854558PMC
December 2013

Imatinib and chronic myeloid leukemia: close to the bone.

Leuk Lymphoma 2013 Aug 27;54(8):1581-2. Epub 2013 Mar 27.

Department of Clinical Therapeutics, University of Athens School of Medicine, Athens, Greece.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3109/10428194.2013.772608DOI Listing
August 2013

TWIST it but don't spin it.

Authors:
Jane F Apperley

Blood 2013 Jul;122(4):470-1

Imperial College London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2013-06-506097DOI Listing
July 2013

Allogeneic stem cell transplantation for chronic myeloid leukemia.

Curr Hematol Malig Rep 2013 Mar;8(1):43-51

Imperial College London at Hammersmith Hospital, London, UK.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/s11899-012-0149-7DOI Listing
March 2013

Lymphodepletion chemotherapy followed by donor leukocytes for post-transplantation relapse of myelofibrosis after previous donor leukocyte infusion failure.

Eur J Haematol 2013 Jan 29;90(1):76-8. Epub 2012 Nov 29.

Department of Haematology, Imperial College at Hammersmith Hospital, London, UK.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1111/ejh.12034
Publisher Site
http://dx.doi.org/10.1111/ejh.12034DOI Listing
January 2013

Significant weight gain in patients with chronic myeloid leukemia after imatinib therapy.

Blood 2012 Dec;120(25):5087-8

Department of Haematology, Imperial College London, Hammersmith Hospital, London, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2012-09-458463DOI Listing
December 2012

Fast-mode duplex qPCR for BCR-ABL1 molecular monitoring: innovation, automation, and harmonization.

Am J Hematol 2012 Jul 6;87(7):717-20. Epub 2012 May 6.

Imperial Molecular Pathology, Imperial College Academic Health Science Centre, London, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ajh.23212DOI Listing
July 2012

Predictive value of early molecular response in patients with chronic myeloid leukemia treated with first-line dasatinib.

Blood 2012 Jul 29;120(2):291-4. Epub 2012 May 29.

Department of Haematology, Imperial College London, Hammersmith Hospital, Du Cane Road, London, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1182/blood-2012-01-407486DOI Listing
July 2012

BCR-ABL1 kinase domain mutations: methodology and clinical evaluation.

Am J Hematol 2012 Mar 9;87(3):298-304. Epub 2012 Jan 9.

Imperial Molecular Pathology Laboratory, Imperial College NHS Trust and Academic Science Centre, Hammersmith Hospital, London W12 OHS, United Kingdom.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/ajh.22272DOI Listing
March 2012

Plerixafor for autologous peripheral blood stem cell mobilization in patients previously treated with fludarabine or lenalidomide.

Biol Blood Marrow Transplant 2012 Feb 13;18(2):314-7. Epub 2011 Oct 13.

Centre Hospitalier et Universitaire de Nantes, Service d'Hématologie Clinique, Nantes, Université de Nantes, Centre d'Investigation Clinique en Cancérologie (CI2C), INSERM CRNCA UMR 892, Nantes, France.

View Article

Download full-text PDF

Source
https://linkinghub.elsevier.com/retrieve/pii/S10838791110040
Publisher Site
http://dx.doi.org/10.1016/j.bbmt.2011.10.003DOI Listing
February 2012