Jane A Little

Jane A Little

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Jane A Little

Jane A Little

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Validation of a composite vascular high-risk profile for adult patients with sickle cell disease.

Am J Hematol 2019 Dec 17;94(12):E312-E314. Epub 2019 Sep 17.

Vascular Medicine Institute, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania.

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http://dx.doi.org/10.1002/ajh.25624DOI Listing
December 2019

Overnight oxygen desaturation index in sickle cell disease: prediction of sleep apnea.

Sleep Med 2019 Dec 21;64:12-14. Epub 2019 Jun 21.

Division of Pulmonary, Critical Care and Sleep Medicine, University Hospitals Cleveland Medical Center, United States; Division of Pulmonary, Critical Care and Sleep Medicine, Louis Stokes Veterans Affair Medical Center, United States.

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http://dx.doi.org/10.1016/j.sleep.2019.06.007DOI Listing
December 2019

Priapism, hemoglobin desaturation, and red blood cell adhesion in men with sickle cell anemia.

Blood Cells Mol Dis 2019 11 5;79:102350. Epub 2019 Aug 5.

Department of Hematology and Oncology, School of Medicine, Case Western Reserve University, Cleveland, OH 44106, USA; Seidman Cancer Center at University Hospitals Cleveland Medical Center, Cleveland, OH 44106, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bcmd.2019.102350DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6744332PMC
November 2019

Mercury leads to abnormal red blood cell adhesion to laminin mediated by membrane sulfatides.

Biochim Biophys Acta Biomembr 2019 06 16;1861(6):1162-1171. Epub 2019 Mar 16.

Case Biomanufacturing and Microfabrication Laboratory, Mechanical and Aerospace Engineering Department, Case Western Reserve University, Cleveland, OH, USA; Biomedical Engineering Department, Case Western Reserve University, Cleveland, OH, USA; Department of Orthopaedics, Case Western Reserve University, Cleveland, OH, USA. Electronic address:

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http://dx.doi.org/10.1016/j.bbamem.2019.03.008DOI Listing
June 2019

Intracardiac or intrapulmonary shunts were present in at least 35% of adults with homozygous sickle cell disease followed in an outpatient clinic.

Haematologica 2019 01 13;104(1):e1-e3. Epub 2018 Jul 13.

Division of Pulmonary and Critical Care Medicine, Department of Medicine, University Hospitals Cleveland Medical Center (UHCMC) and Case Western Reserve University (CWRU)

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http://dx.doi.org/10.3324/haematol.2018.196212DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312006PMC
January 2019

Advances in the Treatment of Sickle Cell Disease.

Mayo Clin Proc 2018 12 7;93(12):1810-1824. Epub 2018 Nov 7.

Division of Pediatric Hematology, Johns Hopkins University School of Medicine, Baltimore, MD. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S00256196183058
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http://dx.doi.org/10.1016/j.mayocp.2018.08.001DOI Listing
December 2018

The Effects of a Single Electronic Music Improvisation Session on the Pain of Adults with Sickle Cell Disease: A Mixed Methods Pilot Study.

J Music Ther 2018 Jun;55(2):156-185

Department of Medicine- Hematology, Case Western Reserve University, University Hospitals Seidman Cancer Center, Cleveland, OH, USA.

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http://dx.doi.org/10.1093/jmt/thy004DOI Listing
June 2018

Red Blood Cell Adhesion to Heme-Activated Endothelial Cells Reflects Clinical Phenotype in Sickle Cell Disease.

Am J Hematol 2018 Jun 15. Epub 2018 Jun 15.

Department of Mechanical and Aerospace Engineering, Case Western Reserve University, Cleveland, OH, USA.

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http://doi.wiley.com/10.1002/ajh.25159
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http://dx.doi.org/10.1002/ajh.25159DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6295270PMC
June 2018

Shear dependent red blood cell adhesion in microscale flow.

Integr Biol (Camb) 2018 04;10(4):194-206

Department of Mechanical and Aerospace Engineering, Case Biomanufacturing and Microfabrication Laboratory, Case Western Reserve University, Glennan 616B, 10900 Euclid Ave., Cleveland, OH, USA. and Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH, USA and Department of Orthopaedics, Case Western Reserve University, Cleveland, OH 44106, USA.

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http://dx.doi.org/10.1039/C8IB00004BDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6421573PMC
April 2018

Association of silent infarcts in sickle cell anemia with decreased annexin A5 resistance.

Blood Cells Mol Dis 2018 03 4;69:53-56. Epub 2017 Sep 4.

Albert Einstein College of Medicine, Department of Pediatrics, Division of Hematology, Bronx, NY 10467, USA.

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http://dx.doi.org/10.1016/j.bcmd.2017.09.001DOI Listing
March 2018

The effects of music therapy on transition outcomes in adolescents and young adults with sickle cell disease.

Int J Adolesc Med Health 2017 Aug 5;31(3). Epub 2017 Aug 5.

Department of Medicine-Hematology, University Hospitals Cleveland Medical Center, Cleveland, OH, USA.

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http://dx.doi.org/10.1515/ijamh-2017-0004DOI Listing
August 2017

Hypoxia-enhanced adhesion of red blood cells in microscale flow.

Microcirculation 2017 07;24(5)

Case Biomanufacturing and Microfabrication Laboratory, Mechanical and Aerospace Engineering Department, Case Western Reserve University, Cleveland, OH, USA.

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http://dx.doi.org/10.1111/micc.12374DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5679205PMC
July 2017

Emerging point-of-care technologies for sickle cell disease screening and monitoring.

Expert Rev Med Devices 2016 Dec 22;13(12):1073-1093. Epub 2016 Nov 22.

a Case Biomanufacturing and Microfabrication Laboratory, Mechanical and Aerospace Engineering Department , Case Western Reserve University , Cleveland , OH , USA.

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http://dx.doi.org/10.1080/17434440.2016.1254038DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5166583PMC
December 2016

Nocturnal hemoglobin desaturation is associated with reticulocytosis in adults with sickle cell disease and is independent of obstructive sleep apnea.

Am J Hematol 2016 Sep 20;91(9):E355-6. Epub 2016 Jun 20.

Division of Hematology-Oncology, Department of Medicine, Case Western Reserve University, University Hospitals, Cleveland, Ohio.

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http://dx.doi.org/10.1002/ajh.24432DOI Listing
September 2016

Sickle cell disease biochip: a functional red blood cell adhesion assay for monitoring sickle cell disease.

Transl Res 2016 07 19;173:74-91.e8. Epub 2016 Mar 19.

Case Biomanufacturing and Microfabrication Laboratory, Mechanical and Aerospace Engineering Department, Case Western Reserve University, Cleveland, Ohio, USA; Biomedical Engineering Department, Case Western Reserve University, Cleveland, Ohio, USA; Department of Orthopedics, Case Western Reserve University, Cleveland, Ohio, USA; Advanced Platform Technology Center, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, Ohio, USA. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S19315244160010
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http://dx.doi.org/10.1016/j.trsl.2016.03.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4959913PMC
July 2016

Intermediaries of branched chain amino acid metabolism induce fetal hemoglobin, and repress SOX6 and BCL11A, in definitive erythroid cells.

Blood Cells Mol Dis 2015 Aug 27;55(2):161-7. Epub 2015 May 27.

Division of Hematology, Department of Oncology, Albert Einstein College of Medicine and Montefiore Medical Center, 1300 Morris Park Blvd., Bronx, NY 10461, United States. Electronic address:

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http://dx.doi.org/10.1016/j.bcmd.2015.05.006DOI Listing
August 2015

Heterogeneous red blood cell adhesion and deformability in sickle cell disease.

Sci Rep 2014 Nov 24;4:7173. Epub 2014 Nov 24.

1] Case Biomanufacturing and Microfabrication Laboratory, Mechanical and Aerospace Engineering Department, Case Western Reserve University, Cleveland, OH, 44106, USA [2] Department of Orthopaedics, Case Western Reserve University, Cleveland, OH, 44106, USA [3] Advanced Platform Technology Center, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, OH, 44106, USA.

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http://dx.doi.org/10.1038/srep07173DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4241514PMC
November 2014

Haemoglobinuria is associated with chronic kidney disease and its progression in patients with sickle cell anaemia.

Br J Haematol 2014 Mar 12;164(5):729-39. Epub 2013 Dec 12.

Section of Hematology-Oncology, Department of Medicine, Comprehensive Sickle Cell Center, University of Illinois at Chicago, Chicago, IL, USA.

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http://dx.doi.org/10.1111/bjh.12690DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3945021PMC
March 2014

Iron overload in sickle cell disease.

Adv Hematol 2010 17;2010:272940. Epub 2010 May 17.

Department of Hematology, Albert Einstein College of Medicine and Montefiore Medical Center, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1155/2010/272940DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2872757PMC
July 2011

Induction of fetal/embryonic globin gene expression depends on intact cell signaling in definitive erythroid cells.

Blood Cells Mol Dis 2011 Feb 20;46(2):125-32. Epub 2010 Nov 20.

Hematology, Department of Medicine, Albert Einstein College of Medicine, Bronx, NY 10461, USA.

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http://dx.doi.org/10.1016/j.bcmd.2010.10.013DOI Listing
February 2011

Epigenetics of beta-globin gene regulation.

Mutat Res 2008 Dec 7;647(1-2):68-76. Epub 2008 Aug 7.

Laboratory of Cellular and Developmental Biology, NIDDK, NIH, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1016/j.mrfmmm.2008.07.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2617773PMC
December 2008

Lactate dehydrogenase as a biomarker of hemolysis-associated nitric oxide resistance, priapism, leg ulceration, pulmonary hypertension, and death in patients with sickle cell disease.

Blood 2006 Mar 15;107(6):2279-85. Epub 2005 Nov 15.

Vascular Medicine Branch, National Heart, Lung and Blood Institute, National Institutes of Health, 10 Center Dr, MSC 1476, Bldg 10CRC, Rm 5-5140, Bethesda, MD 20892, USA.

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http://dx.doi.org/10.1182/blood-2005-06-2373DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1895723PMC
March 2006

Human leukocyte antigen type as a risk factor for nonmelanomatous skin cancer in patients after renal transplantation.

Transplantation 2004 Sep;78(5):775-8

Department of Medicine Residency Program and Clinical Research Center, University of Minnesota, Minneapolis, MN, USA.

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http://dx.doi.org/10.1097/01.tp.0000131666.17216.11DOI Listing
September 2004

Induction of an embryonic globin gene promoter by short-chain fatty acids.

Blood 2003 Dec 14;102(12):4214-22. Epub 2003 Aug 14.

Hematology, Oncology, and Transplantation, Department of Internal Medicine and Masonic Cancer Center, University of Minnesota, in-care-of LCDB, NIH, Bldg 50, Rm 3154, 9000 Rockville Pike, Bethesda, MD, USA.

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http://dx.doi.org/10.1182/blood-2002-12-3766DOI Listing
December 2003