Publications by authors named "Jan-Michael Peters"

100Publications

How DNA loop extrusion mediated by cohesin enables V(D)J recombination.

Curr Opin Cell Biol 2021 Jan 7;70:75-83. Epub 2021 Jan 7.

Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), Campus-Vienna-Biocenter 1, 1030 Vienna, Austria. Electronic address:

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January 2021

Angelika Amon (1967-2020).

Cell 2021 Jan;184(1):10-14

Research Institute of Molecular Pathology, Campus-Vienna-Biocenter 1, 1030 Vienna, Austria. Electronic address:

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January 2021

Conformation of sister chromatids in the replicated human genome.

Nature 2020 10 23;586(7827):139-144. Epub 2020 Sep 23.

Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Vienna BioCenter, Vienna, Austria.

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October 2020

Cohesin-Dependent and -Independent Mechanisms Mediate Chromosomal Contacts between Promoters and Enhancers.

Cell Rep 2020 07;32(3):107929

Nuclear Dynamics Programme, Babraham Institute, Cambridge CB22 3AT, UK; MRC London Institute of Medical Sciences, London W12 0NN, UK; Institute of Clinical Sciences, Faculty of Medicine, Imperial College, London W12 0NN, UK. Electronic address:

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July 2020

PDS5 proteins are required for proper cohesin dynamics and participate in replication fork protection.

J Biol Chem 2020 01 22;295(1):146-157. Epub 2019 Nov 22.

Chromosome Dynamics Group, Spanish National Cancer Research Centre (CNIO), Melchor Fernández Almagro 3, 28029 Madrid, Spain

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January 2020

DNA loop extrusion by human cohesin.

Science 2019 12 21;366(6471):1338-1345. Epub 2019 Nov 21.

Research Institute of Molecular Pathology (IMP), Vienna BioCenter (VBC), 1030 Vienna, Austria.

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December 2019

Self-organization of centromeres by the ParB CTP hydrolase.

Science 2019 11 24;366(6469):1129-1133. Epub 2019 Oct 24.

Department of Fundamental Microbiology (DMF), Faculty of Biology and Medicine (FBM), University of Lausanne (UNIL), Lausanne, Switzerland.

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November 2019

Posing the APC/C E3 Ubiquitin Ligase to Orchestrate Cell Division.

Trends Cell Biol 2019 02 25;29(2):117-134. Epub 2018 Oct 25.

Department of Molecular Machines and Signaling, Max Planck Institute of Biochemistry, Martinsried, 82152, Germany; Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA. Electronic address:

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February 2019

Analysis of chromosomes from mouse oocytes and mammalian cultured cells by light microscopy.

Methods Cell Biol 2018 ;144:287-305

Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), Vienna, Austria. Electronic address:

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December 2018

Dynamics of sister chromatid resolution during cell cycle progression.

J Cell Biol 2018 06 25;217(6):1985-2004. Epub 2018 Apr 25.

Institute of Molecular Biotechnology of the Austrian Academy of Sciences, Vienna BioCenter, Vienna, Austria

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June 2018

Expressing Multi-subunit Complexes Using biGBac.

Methods Mol Biol 2018 ;1764:329-343

Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), Vienna, Austria.

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February 2019

A mechanism of cohesin-dependent loop extrusion organizes zygotic genome architecture.

EMBO J 2017 12 7;36(24):3600-3618. Epub 2017 Dec 7.

Institute of Molecular Biotechnology of the Austrian Academy of Sciences (IMBA), Vienna Biocenter (VBC), Vienna, Austria

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December 2017

BubR1 Promotes Bub3-Dependent APC/C Inhibition during Spindle Assembly Checkpoint Signaling.

Curr Biol 2017 Oct 21;27(19):2915-2927.e7. Epub 2017 Sep 21.

Department of Mechanistic Cell Biology, Max Planck Institute of Molecular Physiology, Otto-Hahn-Strasse 11, 44227 Dortmund, Germany; Centre for Medical Biotechnology, Faculty of Biology, University Duisburg-Essen, Universitätsstrasse, 45141 Essen, Germany. Electronic address:

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October 2017

Cohesin is positioned in mammalian genomes by transcription, CTCF and Wapl.

Nature 2017 04 19;544(7651):503-507. Epub 2017 Apr 19.

Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), Campus-Vienna-Biocenter 1, A-1030 Vienna, Austria.

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April 2017

Topology and structure of an engineered human cohesin complex bound to Pds5B.

Nat Commun 2016 08 23;7:12523. Epub 2016 Aug 23.

Research Institute of Molecular Pathology (IMP), Dr Bohr-Gasse 7, Vienna 1030, Austria.

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August 2016

Cryo-EM of Mitotic Checkpoint Complex-Bound APC/C Reveals Reciprocal and Conformational Regulation of Ubiquitin Ligation.

Mol Cell 2016 08 10;63(4):593-607. Epub 2016 Aug 10.

Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA; Howard Hughes Medical Institute, St. Jude Children's Research Hospital, Memphis, TN 38105, USA. Electronic address:

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August 2016

biGBac enables rapid gene assembly for the expression of large multisubunit protein complexes.

Proc Natl Acad Sci U S A 2016 May 25;113(19):E2564-9. Epub 2016 Apr 25.

Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), 1030 Vienna, Austria;

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May 2016

Intact Cohesion, Anaphase, and Chromosome Segregation in Human Cells Harboring Tumor-Derived Mutations in STAG2.

PLoS Genet 2016 Feb 12;12(2):e1005865. Epub 2016 Feb 12.

Lombardi Comprehensive Cancer Center, Georgetown University School of Medicine, Washington, D.C, United States of America.

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February 2016

The Deubiquitinase USP37 Regulates Chromosome Cohesion and Mitotic Progression.

Curr Biol 2015 Aug 20;25(17):2290-9. Epub 2015 Aug 20.

Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, 600 University Avenue, Toronto, ON M5G 1X5, Canada; Department of Molecular Genetics, University of Toronto, Toronto, ON M5S 1A8, Canada. Electronic address:

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August 2015

Measuring APC/C-Dependent Ubiquitylation In Vitro.

Methods Mol Biol 2016 ;1342:287-303

Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), Dr. Bohrgasse 7, 1030, Vienna, Austria.

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May 2016

RING E3 mechanism for ubiquitin ligation to a disordered substrate visualized for human anaphase-promoting complex.

Proc Natl Acad Sci U S A 2015 Apr 30;112(17):5272-9. Epub 2015 Mar 30.

Department of Structural Biology, Howard Hughes Medical Institute, Department of Microbiology, Immunology, and Biochemistry, University of Tennessee Health Sciences Center, Memphis, TN 38105;

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April 2015

Structure of an APC3-APC16 complex: insights into assembly of the anaphase-promoting complex/cyclosome.

J Mol Biol 2015 Apr 6;427(8):1748-64. Epub 2014 Dec 6.

Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA; Howard Hughes Medical Institute, St. Jude Children's Research Hospital, Memphis, TN 38105 USA. Electronic address:

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April 2015

Characterization of a DNA exit gate in the human cohesin ring.

Science 2014 Nov;346(6212):968-72

Research Institute of Molecular Pathology (IMP), Vienna Biocenter (VBC), 1030 Vienna, Austria.

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November 2014

Mechanism of polyubiquitination by human anaphase-promoting complex: RING repurposing for ubiquitin chain assembly.

Mol Cell 2014 Oct 9;56(2):246-260. Epub 2014 Oct 9.

Department of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN 38105, USA; Howard Hughes Medical Institute, St. Jude Children's Research Hospital, Memphis, TN 38105, USA. Electronic address:

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October 2014

Cohesin's ATPase activity couples cohesin loading onto DNA with Smc3 acetylation.

Curr Biol 2014 Oct 11;24(19):2228-37. Epub 2014 Sep 11.

Research Institute of Molecular Pathology, Dr. Bohr-Gasse 7, 1030 Vienna, Austria. Electronic address:

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October 2014

Aurora B and Cdk1 mediate Wapl activation and release of acetylated cohesin from chromosomes by phosphorylating Sororin.

Proc Natl Acad Sci U S A 2013 Aug 30;110(33):13404-9. Epub 2013 Jul 30.

Research Institute of Molecular Pathology, A-1030 Vienna, Austria.

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August 2013

Sister chromatid cohesion.

Cold Spring Harb Perspect Biol 2012 Nov 1;4(11). Epub 2012 Nov 1.

IMP, Dr. Bohr-Gasse, Vienna, Austria.

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November 2012

The non-redundant function of cohesin acetyltransferase Esco2: some answers and new questions.

Nucleus 2012 Jul 22;3(4):330-4. Epub 2012 May 22.

Max Planck Institute for Biophysical Chemistry, Goettingen, Germany.

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July 2012

The many functions of cohesin--different rings to rule them all?

EMBO J 2012 May 10;31(9):2061-3. Epub 2012 Apr 10.

Research Institute of Molecular Pathology, Vienna, Austria.

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May 2012

Cohesin acetyltransferase Esco2 is a cell viability factor and is required for cohesion in pericentric heterochromatin.

EMBO J 2012 Jan 18;31(1):71-82. Epub 2011 Nov 18.

Genes and Behavior Department, Max Planck Institute for Biophysical Chemistry, Goettingen, Germany.

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January 2012

Substrate binding on the APC/C occurs between the coactivator Cdh1 and the processivity factor Doc1.

Nat Struct Mol Biol 2011 Jan 26;18(1):6-13. Epub 2010 Dec 26.

Research Institute of Molecular Pathology (IMP), Dr. Bohr-Gasse 7, A-1030 Vienna, Austria.

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January 2011

Cohesin is required for higher-order chromatin conformation at the imprinted IGF2-H19 locus.

PLoS Genet 2009 Nov 26;5(11):e1000739. Epub 2009 Nov 26.

Department of Oncology, University of Cambridge, Cancer Research UK Cambridge Research Institute, Cambridge, United Kingdom.

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November 2009

The cohesin complex is required for the DNA damage-induced G2/M checkpoint in mammalian cells.

EMBO J 2009 Sep 23;28(17):2625-35. Epub 2009 Jul 23.

Research Institute of Molecular Pathology (IMP), Vienna, Austria.

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September 2009

Preventing carryover of peptides and proteins in nano LC-MS separations.

Anal Chem 2009 Jul;81(14):5955-60

Institute of Molecular Biotechnology of the Austrian Academy of Science, Dr. Bohr-Gasse 3, A-1030 Vienna, Austria.

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July 2009

Cohesin acetylation: from antiestablishment to establishment.

Mol Cell 2009 Apr;34(1):1-2

Research Institute of Molecular Pathology, Vienna, Austria.

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April 2009

How cohesin and CTCF cooperate in regulating gene expression.

Chromosome Res 2009 24;17(2):201-14. Epub 2009 Mar 24.

Research Institute of Molecular Pathology, Dr. Bohr-Gasse 7, A-1030 Vienna, Austria.

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June 2009

The cohesin complex and its roles in chromosome biology.

Genes Dev 2008 Nov;22(22):3089-114

Research Institute of Molecular Pathology (IMP), A-1030 Vienna, Austria.

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November 2008

Twenty years of cell-cycle conferences in Roscoff.

Nat Cell Biol 2008 Aug;10(8):877-80

Center for Genomic Regulation (CRG), UPF, Barcelona, Spain.

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August 2008

Polo on the Rise-from Mitotic Entry to Cytokinesis with Plk1.

Dev Cell 2008 May;14(5):646-59

Cell Division and Aneuploidy Laboratory, Cancer Research UK London Research Institute, Clare Hall Laboratories, South Mimms, Hertfordshire, EN6 3LD, United Kingdom.

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May 2008

Checkpoint control: the journey continues.

Curr Biol 2008 Feb;18(4):R170-2

Research Institute of Molecular Pathology , Dr. Bohr-Gasse 7, A-1030 Vienna, Austria.

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February 2008

Polo and Aurora kinases: lessons derived from chemical biology.

Curr Opin Cell Biol 2008 Feb 30;20(1):77-84. Epub 2008 Jan 30.

Faculty of Life Sciences, University of Manchester, Michael Smith Building, Manchester, UK.

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February 2008

The Suv39h-HP1 histone methylation pathway is dispensable for enrichment and protection of cohesin at centromeres in mammalian cells.

Chromosoma 2008 Apr 11;117(2):199-210. Epub 2007 Dec 11.

Research Institute of Molecular Pathology (IMP), Dr. Bohr-Gasse 7, 1030 Vienna, Austria.

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April 2008

The complete removal of cohesin from chromosome arms depends on separase.

J Cell Sci 2007 Dec 14;120(Pt 23):4188-96. Epub 2007 Nov 14.

Department of Experimental Pathology, Cancer Institute of the Japanese Foundation for Cancer Research (JFCR), Tokyo, Japan.

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December 2007

Molecular biology. How and when the genome sticks together.

Science 2007 Jul;317(5835):209-10

Research Institute of Molecular Pathology (IMP), Dr. Bohr-Gasse 7, A-1030 Vienna, Austria.

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July 2007

Aurora B controls the association of condensin I but not condensin II with mitotic chromosomes.

J Cell Sci 2007 Apr 13;120(Pt 7):1245-55. Epub 2007 Mar 13.

Research Institute of Molecular Pathology, Dr Bohrgasse 7, A-1030 Vienna, Austria.

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April 2007

Sororin is required for stable binding of cohesin to chromatin and for sister chromatid cohesion in interphase.

Curr Biol 2007 Apr 8;17(7):630-6. Epub 2007 Mar 8.

Research Institute of Molecular Pathology (IMP), Dr Bohr-Gasse 7, A-1030 Vienna, Austria.

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April 2007

Wapl controls the dynamic association of cohesin with chromatin.

Cell 2006 Dec 16;127(5):955-67. Epub 2006 Nov 16.

Research Institute of Molecular Pathology, Dr. Bohr-Gasse 7, A-1030 Vienna, Austria.

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December 2006

The anaphase promoting complex/cyclosome: a machine designed to destroy.

Nat Rev Mol Cell Biol 2006 Sep 9;7(9):644-56. Epub 2006 Aug 9.

Research Institute of Molecular Pathology, Dr. Bohr-Gasse 7, A-1030 Vienna, Austria.

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September 2006

Live-cell imaging reveals a stable cohesin-chromatin interaction after but not before DNA replication.

Curr Biol 2006 Aug;16(15):1571-8

Gene Expression Unit, European Molecular Biology Laboratory, 69117 Heidelberg, Germany.

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August 2006

Cohesin and DNA damage repair.

Exp Cell Res 2006 Aug 22;312(14):2687-93. Epub 2006 Jun 22.

Research Institute of Molecular Pathology (IMP), Vienna, Austria.

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August 2006

Checkpoint activation: don't get mad too much.

Curr Biol 2006 Jun;16(11):R412-4

Research Institute of Molecular Pathology (IMP), Dr. Bohr-Gasse 7, A-1030 Vienna, Austria.

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June 2006

Condensin I stabilizes chromosomes mechanically through a dynamic interaction in live cells.

Curr Biol 2006 Feb;16(4):333-44

Gene Expression and Cell Biology/Biophysics Programmes, EMBL, 69117 Heidelberg, Germany.

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February 2006