Jan-Henning Klusmann

Jan-Henning Klusmann

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Jan-Henning Klusmann

Jan-Henning Klusmann

Publications by authors named "Jan-Henning Klusmann"

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42Publications

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Molecular Approaches to Treating Pediatric Leukemias.

Front Pediatr 2019 6;7:368. Epub 2019 Sep 6.

Department of Pediatric Hematology and Oncology, Martin Luther University Halle-Wittenberg, Halle, Germany.

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http://dx.doi.org/10.3389/fped.2019.00368DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6742719PMC
September 2019

The Regulatory Roles of Long Noncoding RNAs in Acute Myeloid Leukemia.

Front Oncol 2019 9;9:570. Epub 2019 Jul 9.

Department of Pediatrics I, Martin Luther University Halle-Wittenberg, Halle, Germany.

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http://dx.doi.org/10.3389/fonc.2019.00570DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6629768PMC
July 2019

Childhood obesity: increased risk for cardiometabolic disease and cancer in adulthood.

Metabolism 2019 Mar 5;92:147-152. Epub 2018 Dec 5.

Department of Pediatrics I, Martin-Luther-University Halle-Wittenberg, Halle, Germany.

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http://dx.doi.org/10.1016/j.metabol.2018.12.001DOI Listing
March 2019

s exerts developmental stage-specific effects in human hematopoiesis.

Haematologica 2018 08 22;103(8):e336-e340. Epub 2018 Mar 22.

Pediatric Hematology and Oncology, Martin-Luther-University Halle-Wittenberg, Halle, Germany

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http://dx.doi.org/10.3324/haematol.2018.191338DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6068023PMC
August 2018

Endogenous Tumor Suppressor microRNA-193b: Therapeutic and Prognostic Value in Acute Myeloid Leukemia.

J Clin Oncol 2018 04 12;36(10):1007-1016. Epub 2018 Feb 12.

Raj Bhayadia, Razan Jammal, Stephan Emmrich, Jan Fiedler, Adrian Schwarzer, Michael Heuser, Michelle Ng, Dirk Heckl, and Thomas Thum, Hannover Medical School, Hannover; Raj Bhayadia, Michelle Ng, and Jan-Henning Klusmann, University of Halle, Halle; Kathrin Krowiorz, Arefeh Rouhi, Konstanze Döhner, Hartmut Döhner, and Florian Kuchenbauer, University Hospital of Ulm, Ulm; Nadine Haetscher, Susanne Wingert, Sabrina Bothur, and Michael A. Rieger, Goethe University Frankfurt, Frankfurt; Sabrina Bothur and Michael A. Rieger, German Cancer Consortium, and German Cancer Research Center, Heidelberg; Dirk Reinhardt, University Hospital Essen, Essen, Germany; Askar Obulkasim, C. Michel Zwaan, and Maarten Fornerod, Erasmus MC/Sophia Children's Hospital, Rotterdam; Marry van den Heuvel Eibrink, Prinses Maxima Center for Pediatric Oncology, Utrecht, the Netherlands; Tobias Mätzig and R. Keith Humphries, Terry Fox Laboratory, Vancouver, Canada; and Thomas Thum, National Heart and Lung Institute, Imperial College London, London, United Kingdom.

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http://dx.doi.org/10.1200/JCO.2017.75.2204DOI Listing
April 2018

Reduced Erg Dosage Impairs Survival of Hematopoietic Stem and Progenitor Cells.

Stem Cells 2017 07 24;35(7):1773-1785. Epub 2017 Apr 24.

Division of Genetics, Department of Medicine, Brigham and Women's Hospital, Boston, Massachusetts, USA.

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http://dx.doi.org/10.1002/stem.2627DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532742PMC
July 2017

Hematologic Response to Vorinostat Treatment in Relapsed Myeloid Leukemia of Down Syndrome.

Pediatr Blood Cancer 2016 09 18;63(9):1677-9. Epub 2016 May 18.

Department of Pediatric Hematology and Oncology, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1002/pbc.26062DOI Listing
September 2016

Next-generation personalised medicine for high-risk paediatric cancer patients - The INFORM pilot study.

Eur J Cancer 2016 09 29;65:91-101. Epub 2016 Jul 29.

Department of Pediatric Oncology, Hematology & Immunology, Heidelberg University Hospital, Im Neuenheimer Feld 430, Heidelberg, 69120, Germany; German Cancer Consortium (DKTK), Im Neuenheimer Feld 280, Heidelberg, 69120, Germany; Clinical Cooperation Unit Pediatric Oncology, German Cancer Research Center (DKFZ), Im Neuenheimer Feld 280, Heidelberg, 69120, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.ejca.2016.06.009DOI Listing
September 2016

MicroRNA-125b-5p mimic inhibits acute liver failure.

Nat Commun 2016 06 23;7:11916. Epub 2016 Jun 23.

Research Group MicroRNA in Liver Regeneration, Cluster of Excellence REBIRTH, Hannover Medical School, Carl-Neuberg Strasse 1, 30625 Hannover, Germany.

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http://dx.doi.org/10.1038/ncomms11916DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4931005PMC
June 2016

Lost in translation: pluripotent stem cell-derived hematopoiesis.

EMBO Mol Med 2015 Nov;7(11):1388-402

RG Reprogramming and Gene Therapy, REBIRTH Cluster of Excellence Hannover Medical School, Hannover, Germany Institute of Experimental Hematology Hannover Medical School, Hannover, Germany JRG Translational Hematology of Congenital Diseases, REBIRTH Cluster of Excellence Hannover Medical School, Hannover, Germany

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http://dx.doi.org/10.15252/emmm.201505301DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4644373PMC
November 2015

Improved outcome of pediatric patients with acute megakaryoblastic leukemia in the AML-BFM 04 trial.

Ann Hematol 2015 Aug 28;94(8):1327-36. Epub 2015 Apr 28.

Department of Pediatric Hematology and Oncology, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1007/s00277-015-2383-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4488462PMC
August 2015

LincRNAs MONC and MIR100HG act as oncogenes in acute megakaryoblastic leukemia.

Mol Cancer 2014 Jul 15;13:171. Epub 2014 Jul 15.

Pediatric Hematology and Oncology, Hannover Medical School, Carl-Neuberg-Straße 1, 30625 Hannover, Germany.

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http://molecular-cancer.biomedcentral.com/articles/10.1186/1
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http://dx.doi.org/10.1186/1476-4598-13-171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4118279PMC
July 2014

Involvement of p53 in the cytotoxic activity of the NAMPT inhibitor FK866 in myeloid leukemic cells.

Int J Cancer 2013 Feb 12;132(4):766-74. Epub 2012 Aug 12.

Department of Pediatric Hematology and Oncology, Hannover Medical School, Carl Neuberg Str-1, 30625 Hannover, Germany.

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http://dx.doi.org/10.1002/ijc.27726DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3562481PMC
February 2013

miRNAs can increase the efficiency of ex vivo platelet generation.

Ann Hematol 2012 Nov 5;91(11):1673-84. Epub 2012 Jul 5.

Department of Pediatric Hematology and Oncology, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1007/s00277-012-1517-zDOI Listing
November 2012

Prospects and challenges of reprogrammed cells in hematology and oncology.

Pediatr Hematol Oncol 2012 Sep 2;29(6):507-28. Epub 2012 Aug 2.

Department of Pediatric Hematology and Oncology, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.3109/08880018.2012.708707DOI Listing
September 2012

Inhibition of NAMPT pathway by FK866 activates the function of p53 in HEK293T cells.

Biochem Biophys Res Commun 2012 Aug 21;424(3):371-7. Epub 2012 Jun 21.

Department of Pediatrics, Hematology and Oncology, Hannover Medical School, Carl Neuberg Str-1, 30625 Hannover, Germany.

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http://dx.doi.org/10.1016/j.bbrc.2012.06.075DOI Listing
August 2012

Next-generation sequencing for minimal residual disease monitoring in acute myeloid leukemia patients with FLT3-ITD or NPM1 mutations.

Genes Chromosomes Cancer 2012 Jul 27;51(7):689-95. Epub 2012 Mar 27.

Department of Hematology, Hemostasis, Oncology, and Stem Cell Transplantation, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1002/gcc.21955DOI Listing
July 2012

Concomitant aberrant overexpression of RUNX1 and NCAM in regenerating bone marrow of myeloid leukemia of Down's syndrome.

Haematologica 2006 Nov 17;91(11):1473-80. Epub 2006 Oct 17.

Medizinische Hochschule Hannover, Department of Pediatric Hematology and Oncology, Carl-Neuberg-Strasse 1, 30625 Hannover.

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November 2006

Developmental stage-selective effect of somatically mutated leukemogenic transcription factor GATA1.

Nat Genet 2005 Jun 15;37(6):613-9. Epub 2005 May 15.

Division of Hematology/Oncology, Childrens Hospital, Boston, Massachusetts 02115, USA.

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http://dx.doi.org/10.1038/ng1566DOI Listing
June 2005