Jan Zuna

Jan Zuna

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Jan Zuna

Jan Zuna

Publications by authors named "Jan Zuna"

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New biological and genetic classification and therapeutically relevant categories in childhood B-cell precursor acute lymphoblastic leukemia.

F1000Res 2018 28;7. Epub 2018 Sep 28.

Department of Pediatric Hematology and Oncology, Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic.

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https://f1000research.com/articles/7-1569/v1
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http://dx.doi.org/10.12688/f1000research.16074.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173109PMC
March 2019

Two novel fusion genes, AIF1L-ETV6 and ABL1-AIF1L, result together with ETV6-ABL1 from a single chromosomal rearrangement in acute lymphoblastic leukemia with prenatal origin.

Genes Chromosomes Cancer 2018 09 30;57(9):471-477. Epub 2018 Jul 30.

CLIP - Childhood Leukaemia Investigation Prague, Prague, Czech Republic.

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http://dx.doi.org/10.1002/gcc.6DOI Listing
September 2018

Intragenic ERG Deletions Do Not Explain the Biology of ERG-Related Acute Lymphoblastic Leukemia.

PLoS One 2016 5;11(8):e0160385. Epub 2016 Aug 5.

Childhood Leukaemia Investigation Prague (CLIP), Department of Paediatric Haematology and Oncology, 2nd Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0160385PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975502PMC
July 2017

Slower early response to treatment and distinct expression profile of childhood high hyperdiploid acute lymphoblastic leukaemia with DNA index < 1.16.

Genes Chromosomes Cancer 2016 09 23;55(9):727-37. Epub 2016 Jun 23.

CLIP,  Childhood Leukaemia Investigation Prague, Departmentof Paediatric Haematology and Oncology, 2nd Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic.

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http://dx.doi.org/10.1002/gcc.22374DOI Listing
September 2016

Long-term remission of therapy-related acute myeloid leukemia with a new t(11;18)(q23;q21.2) translocation and KMT2A-ME2 (MLL-ME2) fusion gene.

Cancer Genet 2015 Dec 15;208(12):610-4. Epub 2015 Sep 15.

Department of Hemato-oncology, Faculty of Medicine and Dentistry, Palacký University Olomouc, Olomouc, Czech Republic.

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http://dx.doi.org/10.1016/j.cancergen.2015.09.004DOI Listing
December 2015

An unusual case of high hyperdiploid childhood ALL with cryptic BCR/ABL1 rearrangement.

Mol Cytogenet 2014 24;7(1):72. Epub 2014 Oct 24.

Center of Oncocytogenetics, Institute of Medical Biochemistry and Laboratory Diagnostics, General University Hospital in Prague and First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic.

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http://dx.doi.org/10.1186/s13039-014-0072-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213530PMC
October 2014

Reappearance of acute lymphoblastic leukemia 34 years after initial diagnosis: a case report and study of the origin of the reappeared blasts.

Int J Hematol 2013 Apr 19;97(4):525-8. Epub 2013 Feb 19.

Department of Pediatrics, Kyorin University School of Medicine, 6-20-2 Shinkawa, Mitaka-shi, Tokyo, Japan.

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http://dx.doi.org/10.1007/s12185-013-1289-9DOI Listing
April 2013

The adaptor protein NTAL enhances proximal signaling and potentiates corticosteroid-induced apoptosis in T-ALL.

Exp Hematol 2012 May 21;40(5):379-85. Epub 2012 Jan 21.

CLIP-Childhood Leukemia Investigation Prague, Prague, Czech Republic.

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http://dx.doi.org/10.1016/j.exphem.2012.01.011DOI Listing
May 2012

Clonal origins of relapse in ETV6-RUNX1 acute lymphoblastic leukemia.

Blood 2011 Jun 11;117(23):6247-54. Epub 2011 Apr 11.

Section of Haemato-Oncology, Institute of Cancer Research, Sutton, UK.

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http://dx.doi.org/10.1182/blood-2010-10-314674DOI Listing
June 2011

TEL/AML1-positive patients lacking TEL exon 5 resemble canonical TEL/AML1 cases.

Pediatr Blood Cancer 2011 Feb 22;56(2):217-25. Epub 2010 Oct 22.

CLIP, Department of Pediatric Hematology and Oncology, 2nd Faculty of Medicine, Charles University Prague and University Hospital Motol, Prague, Czech Republic.

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http://dx.doi.org/10.1002/pbc.22686DOI Listing
February 2011

Acute leukemias with ETV6/ABL1 (TEL/ABL) fusion: poor prognosis and prenatal origin.

Genes Chromosomes Cancer 2010 Oct;49(10):873-84

Department of Pediatric Hematology and Oncology, CLIP (Childhood Leukaemia Investigation Prague), Charles University Prague, 2nd Faculty of Medicine and University Hospital Motol, Prague, Czech Republic.

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http://dx.doi.org/10.1002/gcc.20796DOI Listing
October 2010

Adaptor molecules expression in normal lymphopoiesis and in childhood leukemia.

Immunol Lett 2009 Feb 11;122(2):185-92. Epub 2009 Feb 11.

CLIP-Childhood Leukemia Investigation Prague, Czech Republic.

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http://dx.doi.org/10.1016/j.imlet.2008.12.008DOI Listing
February 2009

Covert preleukemia driven by MLL gene fusion.

Genes Chromosomes Cancer 2009 Jan;48(1):98-107

Department of Paediatric Haematology and Oncology, Childhood Leukaemia Investigation Prague, Charles University Prague, 2nd Medical School, Czech Republic.

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http://dx.doi.org/10.1002/gcc.20622DOI Listing
January 2009

TEL/AML1 and immunoreceptor gene rearrangements-which comes first?

Leuk Res 2005 Jun 18;29(6):633-9. Epub 2005 Jan 18.

CLIP - Childhood Leukaemia Investigation Prague, 2nd Medical School, Charles University Prague, V Uvalu 84, Prague, Czech Republic.

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http://dx.doi.org/10.1016/j.leukres.2004.11.007DOI Listing
June 2005

TEL deletion analysis supports a novel view of relapse in childhood acute lymphoblastic leukemia.

Clin Cancer Res 2004 Aug;10(16):5355-60

Leukemia Research Fund Centre for Cell and Molecular Biology, Institute of Cancer Research, London, United Kingdom.

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http://dx.doi.org/10.1158/1078-0432.CCR-04-0584DOI Listing
August 2004

Pre-natal, clonal origin of acute lymphoblastic leukaemia in triplets.

Leuk Lymphoma 2003 Dec;44(12):2099-102

CLIP--Childhood Leukaemia Investigation, Prague, Czech Republic.

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http://dx.doi.org/10.1080/1042819031000123393DOI Listing
December 2003