Jan Zuna

Jan Zuna

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Jan Zuna

Jan Zuna

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Relapses and treatment-related events contributed equally to poor prognosis in children with ABL-class fusion positive B-cell acute lymphoblastic leukemia treated according to AIEOP-BFM protocols.

Authors:
Gunnar Cario Veronica Leoni Valentino Conter Andishe Attarbaschi Marketa Zaliova Lucie Sramkova Giovanni Cazzaniga Grazia Fazio Rosemary Sutton Sarah Elitzur Shai Izraeli Melchior Lauten Franco Locatelli Giuseppe Basso Barbara Buldini Anke K Bergmann Jana Lentes Doris Steinemann Gudrun Göhring Brigitte Schlegelberger Oskar A Haas Denis Schewe Swantje Buchmann Anja Moericke Deborah White Tamas Revesz Martin Stanulla Georg Mann Nicole Bodmer Nira Arad-Cohen Jan Zuna Maria Grazia Valsecchi Martin Zimmermann Martin Schrappe Andrea Biondi

Haematologica 2019 Oct 10. Epub 2019 Oct 10.

Clinica Pediatrica and Centro Ricerca Tettamanti, Università di Milano-Bicocca, Monza, Italy.

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http://dx.doi.org/10.3324/haematol.2019.231720DOI Listing
October 2019

Human MLL/KMT2A gene exhibits a second breakpoint cluster region for recurrent MLL-USP2 fusions.

Authors:
Claus Meyer Bruno A Lopes Aurélie Caye-Eude Hélène Cavé Chloé Arfeuille Wendy Cuccuini Rosemary Sutton Nicola C Venn Seung Hwan Oh Grigory Tsaur Gabriele Escherich Tobias Feuchtinger Hansen J Kosasih Seong L Khaw Paul G Ekert Maria S Pombo-de-Oliveira Audrey Bidet Bardya Djahanschiri Ingo Ebersberger Marketa Zaliova Jan Zuna Zuzana Zermanova Vesa Juvonen Renate Panzer Grümayer Grazia Fazio Gianni Cazzaniga Patrizia Larghero Mariana Emerenciano Rolf Marschalek

Leukemia 2019 09 21;33(9):2306-2340. Epub 2019 Mar 21.

DCAL/Institute of Pharmaceutical Biology, Goethe-University Frankfurt, Frankfurt am Main, Germany.

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http://dx.doi.org/10.1038/s41375-019-0451-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6756029PMC
September 2019

deletions in childhood acute lymphoblastic leukemia with rearrangements are mostly polyclonal, prognostically relevant and their detection rate strongly depends on screening method sensitivity.

Authors:
Marketa Zaliova Eliska Potuckova Lenka Hovorkova Alena Musilova Lucie Winkowska Karel Fiser Jan Stuchly Ester Mejstrikova Julia Starkova Jan Zuna Jan Stary Jan Trka

Haematologica 2019 07 10;104(7):1407-1416. Epub 2019 Jan 10.

CLIP - Childhood Leukaemia Investigation Prague.

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http://dx.doi.org/10.3324/haematol.2018.204487DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601096PMC
July 2019

Genomic landscape of pediatric B-other acute lymphoblastic leukemia in a consecutive European cohort.

Authors:
Marketa Zaliova Jan Stuchly Lucie Winkowska Alena Musilova Karel Fiser Martina Slamova Julia Starkova Martina Vaskova Ondrej Hrusak Lucie Sramkova Jan Stary Jan Zuna Jan Trka

Haematologica 2019 07 10;104(7):1396-1406. Epub 2019 Jan 10.

CLIP - Childhood Leukaemia Investigation Prague

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http://www.haematologica.org/lookup/doi/10.3324/haematol.201
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http://dx.doi.org/10.3324/haematol.2018.204974DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601078PMC
July 2019

New biological and genetic classification and therapeutically relevant categories in childhood B-cell precursor acute lymphoblastic leukemia.

Authors:
Jan Starý Jan Zuna Marketa Zaliova

F1000Res 2018 28;7. Epub 2018 Sep 28.

Department of Pediatric Hematology and Oncology, Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic.

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https://f1000research.com/articles/7-1569/v1
Publisher Site
http://dx.doi.org/10.12688/f1000research.16074.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173109PMC
March 2019

Two novel fusion genes, AIF1L-ETV6 and ABL1-AIF1L, result together with ETV6-ABL1 from a single chromosomal rearrangement in acute lymphoblastic leukemia with prenatal origin.

Authors:
Julius Lukes Eliska Potuckova Lucie Sramkova Jan Stary Julia Starkova Jan Trka Felix Votava Jan Zuna Marketa Zaliova

Genes Chromosomes Cancer 2018 09 30;57(9):471-477. Epub 2018 Jul 30.

CLIP - Childhood Leukaemia Investigation Prague, Prague, Czech Republic.

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http://dx.doi.org/10.1002/gcc.6DOI Listing
September 2018

Predictive value of minimal residual disease in Philadelphia-chromosome-positive acute lymphoblastic leukemia treated with imatinib in the European intergroup study of post-induction treatment of Philadelphia-chromosome-positive acute lymphoblastic leukemia, based on immunoglobulin/T-cell receptor and BCR/ABL1 methodologies.

Authors:
Giovanni Cazzaniga Paola De Lorenzo Julia Alten Silja Röttgers Jeremy Hancock Vaskar Saha Anders Castor Hans O Madsen Virginie Gandemer Hélène Cavé Veronica Leoni Rolf Köhler Giulia M Ferrari Kirsten Bleckmann Rob Pieters Vincent van der Velden Jan Stary Jan Zuna Gabriele Escherich Udo Zur Stadt Maurizio Aricò Valentino Conter Martin Schrappe Maria Grazia Valsecchi Andrea Biondi

Haematologica 2018 01 27;103(1):107-115. Epub 2017 Oct 27.

Associazione Italiana Ematologia Oncologia Pediatrica (AIEOP), Centro Ricerca Tettamanti, Pediatric Department, University of Milano-Bicocca, Monza, Italy.

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http://dx.doi.org/10.3324/haematol.2017.176917DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777198PMC
January 2018

ETV6/RUNX1-like acute lymphoblastic leukemia: A novel B-cell precursor leukemia subtype associated with the CD27/CD44 immunophenotype.

Authors:
Marketa Zaliova Michaela Kotrova Silvia Bresolin Jan Stuchly Jan Stary Ondrej Hrusak Geertruy Te Kronnie Jan Trka Jan Zuna Martina Vaskova

Genes Chromosomes Cancer 2017 08 5;56(8):608-616. Epub 2017 May 5.

CLIP-Childhood Leukaemia Investigation Prague, Czech Republic.

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http://dx.doi.org/10.1002/gcc.22464DOI Listing
August 2017

Intragenic ERG Deletions Do Not Explain the Biology of ERG-Related Acute Lymphoblastic Leukemia.

Authors:
Eliska Potuckova Jan Zuna Lenka Hovorkova Julia Starkova Jan Stary Jan Trka Marketa Zaliova

PLoS One 2016 5;11(8):e0160385. Epub 2016 Aug 5.

Childhood Leukaemia Investigation Prague (CLIP), Department of Paediatric Haematology and Oncology, 2nd Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0160385PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975502PMC
July 2017

Acute lymphoblastic leukemia with aleukemic prodrome: preleukemic dynamics and possible mechanisms of immunosurveillance.

Authors:
Olga Zimmermannova Marketa Zaliova Anthony V Moorman Halima Al-Shehhi Eva Fronkova Zuzana Zemanova Tomas Kalina Ajay Vora Jan Stary Jan Trka Ondrej Hrusak Jan Zuna

Haematologica 2017 06 2;102(6):e225-e228. Epub 2017 Mar 2.

CLIP, Childhood Leukaemia Investigation Prague, Czech Republic

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http://dx.doi.org/10.3324/haematol.2016.161380DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451349PMC
June 2017

Monitoring of childhood ALL using genomic breakpoints identifies a subgroup with CML-like biology.

Authors:
Lenka Hovorkova Marketa Zaliova Nicola C Venn Kirsten Bleckmann Marie Trkova Eliska Potuckova Martina Vaskova Jana Linhartova Katerina Machova Polakova Eva Fronkova Walter Muskovic Jodie E Giles Peter J Shaw Gunnar Cario Rosemary Sutton Jan Stary Jan Trka Jan Zuna

Blood 2017 05 22;129(20):2771-2781. Epub 2017 Mar 22.

Childhood Leukemia Investigation Prague (CLIP) and.

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http://dx.doi.org/10.1182/blood-2016-11-749978DOI Listing
May 2017

Distinct bilineal leukemia immunophenotypes are not genetically determined.

Authors:
Michaela Kotrova Alena Musilova Jan Stuchly Karel Fiser Julia Starkova Ester Mejstrikova Jan Stary Jan Zuna Ondrej Hrusak Jan Trka Marketa Zaliova

Blood 2016 11 13;128(18):2263-2266. Epub 2016 Sep 13.

Childhood Leukaemia Investigation Prague, and.

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http://dx.doi.org/10.1182/blood-2016-07-725861DOI Listing
November 2016

Slower early response to treatment and distinct expression profile of childhood high hyperdiploid acute lymphoblastic leukaemia with DNA index < 1.16.

Authors:
Marketa Zaliova Lenka Hovorkova Martina Vaskova Ondrej Hrusak Jan Stary Jan Zuna

Genes Chromosomes Cancer 2016 09 23;55(9):727-37. Epub 2016 Jun 23.

CLIP,  Childhood Leukaemia Investigation Prague, Departmentof Paediatric Haematology and Oncology, 2nd Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic.

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http://dx.doi.org/10.1002/gcc.22374DOI Listing
September 2016

Characterization of leukemias with ETV6-ABL1 fusion.

Authors:
Marketa Zaliova Anthony V Moorman Giovanni Cazzaniga Martin Stanulla Richard C Harvey Kathryn G Roberts Sue L Heatley Mignon L Loh Marina Konopleva I-Ming Chen Olga Zimmermannova Claire Schwab Owen Smith Marie-Joelle Mozziconacci Christian Chabannon Myungshin Kim J H Frederik Falkenburg Alice Norton Karen Marshall Oskar A Haas Julia Starkova Jan Stuchly Stephen P Hunger Deborah White Charles G Mullighan Cheryl L Willman Jan Stary Jan Trka Jan Zuna

Haematologica 2016 09 26;101(9):1082-93. Epub 2016 May 26.

CLIP, Department of Pediatric Hematology and Oncology, 2 Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic

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http://dx.doi.org/10.3324/haematol.2016.144345DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5060025PMC
September 2016

Implications of delayed bone marrow aspirations at the end of treatment induction for risk stratification and outcome in children with acute lymphoblastic leukaemia.

Authors:
Jan Zuna Anja Moericke Mari Arens Rolf Koehler Renate Panzer-Grümayer Claus R Bartram Susanna Fischer Eva Fronkova Marketa Zaliova André Schrauder Martin Stanulla Martin Zimmermann Jan Trka Jan Stary Andishe Attarbaschi Georg Mann Martin Schrappe Gunnar Cario

Br J Haematol 2016 06 23;173(5):742-8. Epub 2016 Feb 23.

Department of Paediatrics, University Medical Centre Schleswig-Holstein, Campus Kiel, Kiel, Germany.

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http://dx.doi.org/10.1111/bjh.13989DOI Listing
June 2016

Long-term remission of therapy-related acute myeloid leukemia with a new t(11;18)(q23;q21.2) translocation and KMT2A-ME2 (MLL-ME2) fusion gene.

Authors:
Tomáš Szotkowski Marie Jarošová Olga Zimmermannová Claus Meyer Rolf Marschalek Jan Zuna Jaromír Hubáček Karel Indrák

Cancer Genet 2015 Dec 15;208(12):610-4. Epub 2015 Sep 15.

Department of Hemato-oncology, Faculty of Medicine and Dentistry, Palacký University Olomouc, Olomouc, Czech Republic.

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http://dx.doi.org/10.1016/j.cancergen.2015.09.004DOI Listing
December 2015

[The prospects for children with acute lymphoblastic leukemia of being cured has increased in the Czech Republic in the 21st century to 90% - outcome of the ALL-IC BFM 2002 trial].

Authors:
Kateřina Zdráhalová Jaroslav Štěrba Jiří Domanský Bohumír Blažek Hana Ptoszková Vladimír Mihál Zbyněk Novák Jiří Hak Daniela Procházková Zdena Černá Pavel Timr Yahia Jabali Petr Sedláček Petr Smíšek Zuzana Zemanová Marie Jarošová Alena Houdková Ester Mejstříková Ondřej Hrušák Jan Zuna Iveta Janotová Jan Trka Jan Starý

Cas Lek Cesk 2015 ;154(2):79-89

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October 2015

Characterization of 46 patient-specific BCR-ABL1 fusions and detection of SNPs upstream and downstream the breakpoints in chronic myeloid leukemia using next generation sequencing.

Authors:
Jana Linhartova Lenka Hovorkova Simona Soverini Adela Benesova Monika Jaruskova Hana Klamova Jan Zuna Katerina Machova Polakova

Mol Cancer 2015 Apr 18;14:89. Epub 2015 Apr 18.

Institute of Hematology and Blood Transfusion, Prague, Czech Republic.

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http://dx.doi.org/10.1186/s12943-015-0363-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4409993PMC
April 2015

An unusual case of high hyperdiploid childhood ALL with cryptic BCR/ABL1 rearrangement.

Authors:
Libuse Lizcova Zuzana Zemanova Halka Lhotska Jan Zuna Lenka Hovorkova Ester Mejstrikova Eva Malinova Jana Rabasova Ivan Raska Lucie Sramkova Jan Stary Kyra Michalova

Mol Cytogenet 2014 24;7(1):72. Epub 2014 Oct 24.

Center of Oncocytogenetics, Institute of Medical Biochemistry and Laboratory Diagnostics, General University Hospital in Prague and First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic.

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http://dx.doi.org/10.1186/s13039-014-0072-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213530PMC
October 2014

RAG-mediated recombination is the predominant driver of oncogenic rearrangement in ETV6-RUNX1 acute lymphoblastic leukemia.

Authors:
Elli Papaemmanuil Inmaculada Rapado Yilong Li Nicola E Potter David C Wedge Jose Tubio Ludmil B Alexandrov Peter Van Loo Susanna L Cooke John Marshall Inigo Martincorena Jonathan Hinton Gunes Gundem Frederik W van Delft Serena Nik-Zainal David R Jones Manasa Ramakrishna Ian Titley Lucy Stebbings Catherine Leroy Andrew Menzies John Gamble Ben Robinson Laura Mudie Keiran Raine Sarah O'Meara Jon W Teague Adam P Butler Giovanni Cazzaniga Andrea Biondi Jan Zuna Helena Kempski Markus Muschen Anthony M Ford Michael R Stratton Mel Greaves Peter J Campbell

Nat Genet 2014 Feb 12;46(2):116-25. Epub 2014 Jan 12.

1] Cancer Genome Project, Wellcome Trust Sanger Institute, Hinxton, UK. [2] Addenbrooke's National Health Service (NHS) Foundation Trust, Cambridge, UK. [3] Department of Haematology, University of Cambridge, Cambridge, UK. [4].

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http://dx.doi.org/10.1038/ng.2874DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3960636PMC
February 2014

Molecular characterization and clinical impact of t(11;15)(q23;q14-15) MLL-CASC5 rearrangement.

Authors:
John Jeongseok Yang Tae Sung Park Seung-Tae Lee Ja-Young Seo Seung Hwan Oh Eun Hae Cho Sabine Strehl Nora Mühlegger Michael N Dworzak Jan Zuna Dagmar Pospisilova Claus Meyer Rolf Marschalek Hee-Jin Kim Sun-Hee Kim

Haematologica 2014 Jan;99(1):e11-3

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http://dx.doi.org/10.3324/haematol.2013.095638DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4007919PMC
January 2014

Quiescent leukaemic cells account for minimal residual disease in childhood lymphoblastic leukaemia.

Authors:
Christoph Lutz Petter S Woll Georgina Hall Anders Castor Helene Dreau Giovanni Cazzaniga Jan Zuna Christina Jensen Sally A Clark Andrea Biondi Chris Mitchell Helen Ferry Anna Schuh Veronica Buckle Sten-Eirik W Jacobsen Tariq Enver

Leukemia 2013 Apr 22;27(5):1204-1207. Epub 2012 Oct 22.

University College London, Cancer Institute, London WC1E 6BT, UK.

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http://dx.doi.org/10.1038/leu.2012.306DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4693965PMC
April 2013

Reappearance of acute lymphoblastic leukemia 34 years after initial diagnosis: a case report and study of the origin of the reappeared blasts.

Authors:
Fumio Bessho Nobuyuki Takayama Eva Fronkova Jan Zuna

Int J Hematol 2013 Apr 19;97(4):525-8. Epub 2013 Feb 19.

Department of Pediatrics, Kyorin University School of Medicine, 6-20-2 Shinkawa, Mitaka-shi, Tokyo, Japan.

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http://dx.doi.org/10.1007/s12185-013-1289-9DOI Listing
April 2013

The adaptor protein NTAL enhances proximal signaling and potentiates corticosteroid-induced apoptosis in T-ALL.

Authors:
Karel Svojgr Tomas Kalina Veronika Kanderova Tereza Skopcova Tomas Brdicka Jan Zuna

Exp Hematol 2012 May 21;40(5):379-85. Epub 2012 Jan 21.

CLIP-Childhood Leukemia Investigation Prague, Prague, Czech Republic.

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http://dx.doi.org/10.1016/j.exphem.2012.01.011DOI Listing
May 2012

High expression of cytoskeletal protein drebrin in TEL/AML1pos B-cell precursor acute lymphoblastic leukemia identified by a novel monoclonal antibody.

Authors:
Martina Vaskova Martin Kovac Petra Volna Pavla Angelisova Ester Mejstrikova Jan Zuna Tomas Brdicka Ondrej Hrusak

Leuk Res 2011 Aug 16;35(8):1111-3. Epub 2011 Apr 16.

Childhood Leukemia Investigation Prague (CLIP), Prague, Czech Republic.

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http://dx.doi.org/10.1016/j.leukres.2011.03.028DOI Listing
August 2011

Clonal origins of relapse in ETV6-RUNX1 acute lymphoblastic leukemia.

Authors:
Frederik W van Delft Sharon Horsley Sue Colman Kristina Anderson Caroline Bateman Helena Kempski Jan Zuna Cornelia Eckert Vaskar Saha Lyndal Kearney Anthony Ford Mel Greaves

Blood 2011 Jun 11;117(23):6247-54. Epub 2011 Apr 11.

Section of Haemato-Oncology, Institute of Cancer Research, Sutton, UK.

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http://dx.doi.org/10.1182/blood-2010-10-314674DOI Listing
June 2011

TEL/AML1-positive patients lacking TEL exon 5 resemble canonical TEL/AML1 cases.

Authors:
Marketa Zaliova Claus Meyer Gunnar Cario Martina Vaskova Rolf Marschalek Jan Stary Jan Zuna Jan Trka

Pediatr Blood Cancer 2011 Feb 22;56(2):217-25. Epub 2010 Oct 22.

CLIP, Department of Pediatric Hematology and Oncology, 2nd Faculty of Medicine, Charles University Prague and University Hospital Motol, Prague, Czech Republic.

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http://dx.doi.org/10.1002/pbc.22686DOI Listing
February 2011

ETV6/RUNX1 (TEL/AML1) is a frequent prenatal first hit in childhood leukemia.

Authors:
Jan Zuna Jozef Madzo Ondrej Krejci Zuzana Zemanova Marketa Kalinova Katerina Muzikova Michal Zapotocky Julia Starkova Ondrej Hrusak Jiri Horak Jan Trka

Blood 2011 Jan;117(1):368-9; author reply 370-1

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http://dx.doi.org/10.1182/blood-2010-09-309070DOI Listing
January 2011

Acute leukemias with ETV6/ABL1 (TEL/ABL) fusion: poor prognosis and prenatal origin.

Authors:
Jan Zuna Marketa Zaliova Katerina Muzikova Claus Meyer Libuse Lizcova Zuzana Zemanova Jana Brezinova Felix Votava Rolf Marschalek Jan Stary Jan Trka

Genes Chromosomes Cancer 2010 Oct;49(10):873-84

Department of Pediatric Hematology and Oncology, CLIP (Childhood Leukaemia Investigation Prague), Charles University Prague, 2nd Faculty of Medicine and University Hospital Motol, Prague, Czech Republic.

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http://dx.doi.org/10.1002/gcc.20796DOI Listing
October 2010

Prognosis of children with mixed phenotype acute leukemia treated on the basis of consistent immunophenotypic criteria.

Authors:
Ester Mejstrikova Jana Volejnikova Eva Fronkova Katerina Zdrahalova Tomas Kalina Jaroslav Sterba Yahia Jabali Vladimir Mihal Bohumir Blazek Zdena Cerna Daniela Prochazkova Jiri Hak Zuzana Zemanova Marie Jarosova Alexandra Oltova Petr Sedlacek Jiri Schwarz Jan Zuna Jan Trka Jan Stary Ondrej Hrusak

Haematologica 2010 Jun 9;95(6):928-35. Epub 2010 Feb 9.

CLIP-Childhood Leukemia Investigation Prague Department of Pediatric Hematology and Oncology, Charles University, 2ndFaculty of Medicine and University Hospital Motol, Prague, Czech Republic.

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http://dx.doi.org/10.3324/haematol.2009.014506DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878790PMC
June 2010

Backtracking of ALL to cord blood.

Authors:
Jan Zuna Zuzana Prouzova Tomas Kalina Libuse Lizcova Zuzana Zemanova Katerina Muzikova Sarka Rahmatova Jules P P Meijerink Jan Trka

Leuk Res 2009 Aug 8;33(8):e107-8. Epub 2009 Feb 8.

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http://dx.doi.org/10.1016/j.leukres.2009.01.013DOI Listing
August 2009

Adaptor molecules expression in normal lymphopoiesis and in childhood leukemia.

Authors:
Karel Svojgr Tatiana Burjanivova Martina Vaskova Tomas Kalina Jan Stary Jan Trka Jan Zuna

Immunol Lett 2009 Feb 11;122(2):185-92. Epub 2009 Feb 11.

CLIP-Childhood Leukemia Investigation Prague, Czech Republic.

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http://dx.doi.org/10.1016/j.imlet.2008.12.008DOI Listing
February 2009

Covert preleukemia driven by MLL gene fusion.

Authors:
Jan Zuna Tatiana Burjanivova Ester Mejstrikova Zuzana Zemanova Katerina Muzikova Claus Meyer Sharon W Horsley Lyndal Kearney Susan Colman Hana Ptoszkova Rolf Marschalek Ondrej Hrusak Jan Stary Mel Greaves Jan Trka

Genes Chromosomes Cancer 2009 Jan;48(1):98-107

Department of Paediatric Haematology and Oncology, Childhood Leukaemia Investigation Prague, Charles University Prague, 2nd Medical School, Czech Republic.

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http://dx.doi.org/10.1002/gcc.20622DOI Listing
January 2009

Prenatal origin of childhood AML occurs less frequently than in childhood ALL.

Authors:
Tatiana Burjanivova Jozef Madzo Katerina Muzikova Claus Meyer Bjoern Schneider Felix Votava Rolf Marschalek Jan Stary Jan Trka Jan Zuna

BMC Cancer 2006 Apr 21;6:100. Epub 2006 Apr 21.

CLIP-Childhood Leukaemia Investigation Prague, Czech Republic.

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http://dx.doi.org/10.1186/1471-2407-6-100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1463004PMC
April 2006

TEL/AML1 and immunoreceptor gene rearrangements-which comes first?

Authors:
Jan Zuna Ondrej Krejci Jozef Madzo Eva Fronkova Lucie Sramkova Ondrej Hrusak Tomas Kalina Martina Vaskova Jan Stary Jan Trka

Leuk Res 2005 Jun 18;29(6):633-9. Epub 2005 Jan 18.

CLIP - Childhood Leukaemia Investigation Prague, 2nd Medical School, Charles University Prague, V Uvalu 84, Prague, Czech Republic.

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http://dx.doi.org/10.1016/j.leukres.2004.11.007DOI Listing
June 2005

TEL deletion analysis supports a novel view of relapse in childhood acute lymphoblastic leukemia.

Authors:
Jan Zuna Anthony M Ford Martina Peham Naina Patel Vaskar Saha Cornelia Eckert Joachim Köchling Renate Panzer-Grümayer Jan Trka Mel Greaves

Clin Cancer Res 2004 Aug;10(16):5355-60

Leukemia Research Fund Centre for Cell and Molecular Biology, Institute of Cancer Research, London, United Kingdom.

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http://dx.doi.org/10.1158/1078-0432.CCR-04-0584DOI Listing
August 2004

Pre-natal, clonal origin of acute lymphoblastic leukaemia in triplets.

Authors:
Jan Zuna Katerina Muzikova Anthony M Ford Ana Teresa Maia Ondrej Krejci Katerina Tousovska Irina Oravkinova Mel Greaves Jan Trka

Leuk Lymphoma 2003 Dec;44(12):2099-102

CLIP--Childhood Leukaemia Investigation, Prague, Czech Republic.

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http://dx.doi.org/10.1080/1042819031000123393DOI Listing
December 2003

Slower molecular response to treatment predicts poor outcome in patients with TEL/AML1 positive acute lymphoblastic leukemia: prospective real-time quantitative reverse transcriptase-polymerase chain reaction study.

Authors:
Jozef Madzo Jan Zuna Katerina Muzíková Markéta Kalinová Ondrej Krejcí Ondrej Hrusák Berta Otová Jan Starý Jan Trka

Cancer 2003 Jan;97(1):105-13

Childhood Leukemia Investigation Prague, Prague, Czech Republic.

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http://dx.doi.org/10.1002/cncr.11043DOI Listing
January 2003

Significance of real-time quantitative PCR detection of p16 gene deletions in childhood acute lymphoblastic leukemia.

Authors:
Jan Zuna Katerina Muzikova Ondrej Hrusak Jan Stary Jan Trka

Haematologica 2002 Jun;87(6):668-9

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June 2002