Jan W Eriksson

Jan W Eriksson

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Jan W Eriksson

Publications by authors named "Jan W Eriksson"

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Adipocytes express tissue factor and FVII and are procoagulant in a TF/FVIIa-dependent manner.

Ups J Med Sci 2019 Aug 13;124(3):158-167. Epub 2019 Aug 13.

Department of Medical Sciences, Clinical Chemistry, Uppsala University , Uppsala , Sweden.

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http://dx.doi.org/10.1080/03009734.2019.1645248DOI Listing
August 2019

Efficacy and safety of oral semaglutide in patients with type 2 diabetes and moderate renal impairment (PIONEER 5): a placebo-controlled, randomised, phase 3a trial.

Lancet Diabetes Endocrinol 2019 Jul 9;7(7):515-527. Epub 2019 Jun 9.

Division of Diabetes, Endocrinology, and Metabolism, Department of Internal Medicine, University of Nebraska Medical Center, Omaha, NE, USA.

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http://dx.doi.org/10.1016/S2213-8587(19)30192-5DOI Listing
July 2019

Estrogen interacts with glucocorticoids in the regulation of lipocalin 2 expression in human adipose tissue. Reciprocal roles of estrogen receptor α and β in insulin resistance?

Mol Cell Endocrinol 2019 Jun 3;490:28-36. Epub 2019 Apr 3.

Department of Medical Sciences, Clinical Diabetes and Metabolism, Uppsala University, Uppsala, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.mce.2019.04.002DOI Listing
June 2019

Is the Brain a Key Player in Glucose Regulation and Development of Type 2 Diabetes?

Front Physiol 2019 26;10:457. Epub 2019 Apr 26.

Department of Medical Sciences, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.3389/fphys.2019.00457DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6524713PMC
April 2019

Emerging Role of SGLT-2 Inhibitors for the Treatment of Obesity.

Drugs 2019 Feb;79(3):219-230

Department of Medical Sciences, Clinical Diabetes and Metabolism, Uppsala University, 751 85, Uppsala, Sweden.

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http://dx.doi.org/10.1007/s40265-019-1057-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394798PMC
February 2019

Plasma metabolomic patterns in patients with exhaustion disorder.

Stress 2019 01 7;22(1):17-26. Epub 2018 Aug 7.

b The Institute of Stress Medicine , Gothenburg , Sweden Region Västra Götaland.

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http://dx.doi.org/10.1080/10253890.2018.1494150DOI Listing
January 2019

Complications of type 2 diabetes mellitus in Ramallah and al-Bireh: The Palestinian Diabetes Complications and Control Study (PDCCS).

Prim Care Diabetes 2018 12 30;12(6):547-557. Epub 2018 Jul 30.

Institute of Community and Public Health (ICPH), Birzeit University, Palestine. Electronic address:

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http://dx.doi.org/10.1016/j.pcd.2018.07.002DOI Listing
December 2018

Calcineurin is an important factor involved in glucose uptake in human adipocytes.

Mol Cell Biochem 2018 Aug 27;445(1-2):157-168. Epub 2018 Jan 27.

Department of Medical Sciences, University of Uppsala, 751 85, Uppsala, Sweden.

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http://dx.doi.org/10.1007/s11010-017-3261-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060758PMC
August 2018

Comment on Suissa. Lower Risk of Death With SGLT2 Inhibitors in Observational Studies: Real or Bias? Diabetes Care 2018;41:6-10.

Diabetes Care 2018 06;41(6):e104-e105

Department of Medical Sciences, Clinical Diabetes and Metabolism, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.2337/dc18-0339DOI Listing
June 2018

Whole-Body Imaging of Tissue-specific Insulin Sensitivity and Body Composition by Using an Integrated PET/MR System: A Feasibility Study.

Radiology 2018 01 25;286(1):271-278. Epub 2017 Aug 25.

From the Sections of Radiology (E.J., K.H., H.A., J.K.) and Nuclear Medicine (M.L.), Department of Surgical Sciences, and Department of Medical Sciences (J.W.E.), Uppsala University, Akademiska Sjukhuset, SE-75185 Uppsala, Sweden; Centre for Clinical Research Sörmland, Uppsala University, Eskilstuna, Sweden (E.J.); Uppsala-Örebro Regional Research Council, Uppsala, Sweden (E.J.); Department of Medical Physics, Uppsala University Hospital, Uppsala, Sweden (M.L.); AstraZeneca R&D, Gothenburg, Sweden (S.S.); Department of Medicine, Sahlgrenska Academy at Gothenburg University, Gothenburg, Sweden (S.S.); and Antaros Medical, Mölndal, Sweden (H.A., J.K.).

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http://dx.doi.org/10.1148/radiol.2017162949DOI Listing
January 2018

Fatty Acid Proportions in Plasma Cholesterol Esters and Phospholipids Are Positively Correlated in Various Swedish Populations.

J Nutr 2017 11 20;147(11):2118-2125. Epub 2017 Sep 20.

Department of Public Health and Caring Sciences, Clinical Nutrition and Metabolism Unit,

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http://dx.doi.org/10.3945/jn.117.254250DOI Listing
November 2017

Genotype-based recall to study metabolic effects of genetic variation: a pilot study of PPARG Pro12Ala carriers.

Ups J Med Sci 2017 Nov 5;122(4):234-242. Epub 2018 Jan 5.

b Department of Medical Sciences, Molecular Epidemiology and Science for Life Laboratory , Uppsala University , Sweden.

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http://dx.doi.org/10.1080/03009734.2017.1405127DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5810227PMC
November 2017

Second line initiation of insulin compared with DPP-4 inhibitors after metformin monotherapy is associated with increased risk of all-cause mortality, cardiovascular events, and severe hypoglycemia.

Diabetes Res Clin Pract 2017 Jan 19;123:199-208. Epub 2016 Dec 19.

Department of Medical Sciences, Clinical Diabetes and Metabolism, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1016/j.diabres.2016.12.004DOI Listing
January 2017

Patient-reported outcomes and visual acuity after 12months of anti-VEGF-treatment for sight-threatening diabetic macular edema in a real world setting.

Diabetes Res Clin Pract 2016 Nov 21;121:157-165. Epub 2016 Sep 21.

School of Education, Health and Social Studies, Dalarna University, Falun, Sweden; Department of Medical Sciences, Uppsala University, Uppsala, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.diabres.2016.09.015DOI Listing
November 2016

Gastric Bypass Reduces Symptoms and Hormonal Responses in Hypoglycemia.

Diabetes 2016 09 16;65(9):2667-75. Epub 2016 Jun 16.

Department of Medical Sciences, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.2337/db16-0341DOI Listing
September 2016

Incidence, prevalence and mortality of type 2 diabetes requiring glucose-lowering treatment, and associated risks of cardiovascular complications: a nationwide study in Sweden, 2006-2013.

Diabetologia 2016 08 18;59(8):1692-701. Epub 2016 May 18.

Department of Clinical Science and Education, Division of Internal Medicine, Unit for Diabetes Research, Karolinska Institutet, Södersjukhuset, Stockholm, Sweden.

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http://dx.doi.org/10.1007/s00125-016-3971-yDOI Listing
August 2016

Microdialysis and proteomics of subcutaneous interstitial fluid reveals increased galectin-1 in type 2 diabetes patients.

Metabolism 2016 07 13;65(7):998-1006. Epub 2016 Apr 13.

Department of Molecular and Clinical Medicine, Wallenberg Laboratory, Institute of Medicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.metabol.2016.04.003DOI Listing
July 2016

Sulphonylurea compared to DPP-4 inhibitors in combination with metformin carries increased risk of severe hypoglycemia, cardiovascular events, and all-cause mortality.

Diabetes Res Clin Pract 2016 Jul 6;117:39-47. Epub 2016 May 6.

Cardiology Unit, Department of Medicine, Solna, Karolinska Institute, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.diabres.2016.04.055DOI Listing
July 2016

Markers of fibrinolysis may predict development of lower extremity arterial disease in patients with diabetes: A longitudinal prospective cohort study with 10 years of follow-up.

Diab Vasc Dis Res 2016 05 27;13(3):183-91. Epub 2016 Jan 27.

Department of Medical Sciences, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1177/1479164115618516DOI Listing
May 2016

Lipocalin 2 produces insulin resistance and can be upregulated by glucocorticoids in human adipose tissue.

Mol Cell Endocrinol 2016 May 10;427:124-32. Epub 2016 Mar 10.

Department of Medical Sciences, Uppsala University, Uppsala, Sweden. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S03037207163005
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http://dx.doi.org/10.1016/j.mce.2016.03.011DOI Listing
May 2016

Evaluation of reference genes for gene expression studies in human brown adipose tissue.

Adipocyte 2015 Oct-Dec;4(4):280-5. Epub 2015 May 28.

Department of Molecular and Clinical Medicine; Institute of Medicine; The Sahlgrenska Academy; University of Gothenburg ; Gothenburg, Sweden.

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http://dx.doi.org/10.1080/21623945.2015.1039884DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4573192PMC
October 2015

Cyclosporine A and tacrolimus reduce the amount of GLUT4 at the cell surface in human adipocytes: increased endocytosis as a potential mechanism for the diabetogenic effects of immunosuppressive agents.

J Clin Endocrinol Metab 2014 Oct 8;99(10):E1885-94. Epub 2014 Jul 8.

Department of Medical Sciences (M.J.P., J.W.E.), Uppsala University, 751 85 Uppsala, Sweden; Center for Neuroscience and Cell Biology (M.J.P., E.C.), University of Coimbra, 3000-214 Coimbra, Portugal; Department of Molecular and Clinical Medicine (J.P., M.K.S.), the Sahlgrenska Academy at University of Gothenburg, 413 45 Gothenburg, Sweden; Department of Surgery (M.R.), Sahlgrenska University Hospital, 413 45 Gothenburg, Sweden; Centre for Marine Sciences (M.A.), Centre of Marine Sciences, Faculty of Sciences and Technology, University of Algarve, 8005-139 Faro, Portugal; and The Portuguese Diabetes Association (E.C.), 1250-203 Lisbon, Portugal.

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http://dx.doi.org/10.1210/jc.2014-1266DOI Listing
October 2014

Cardiomyocyte-specific loss of diacylglycerol acyltransferase 1 (DGAT1) reproduces the abnormalities in lipids found in severe heart failure.

J Biol Chem 2014 Oct 25;289(43):29881-91. Epub 2014 Aug 25.

From the Divisions of Preventive Medicine and Nutrition and Cardiology, Columbia University College of Physicians and Surgeons, New York, New York 10032, Division of Endocrinology, Diabetes, and Metabolism, New York University Langone School of Medicine, New York, New York 10016

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http://www.jbc.org/content/289/43/29881.full.pdf
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http://www.jbc.org/lookup/doi/10.1074/jbc.M114.601864
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http://dx.doi.org/10.1074/jbc.M114.601864DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4207999PMC
October 2014

FKBP5 expression in human adipose tissue increases following dexamethasone exposure and is associated with insulin resistance.

Metabolism 2014 Sep 4;63(9):1198-208. Epub 2014 Jun 4.

Department of Medical Sciences, Uppsala University, Uppsala, Sweden; AstraZeneca R&D, Mölndal, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.metabol.2014.05.015DOI Listing
September 2014

Short and long term in vivo effects of Cyclosporine A and Sirolimus on genes and proteins involved in lipid metabolism in Wistar rats.

Metabolism 2014 May 11;63(5):702-15. Epub 2014 Feb 11.

Center for Neuroscience and Cell Biology, University of Coimbra, 3000-517 Coimbra, Portugal; The Portuguese Diabetes Association (APDP-ERC), 1250 203 Lisbon, Portugal. Electronic address:

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http://dx.doi.org/10.1016/j.metabol.2014.02.004DOI Listing
May 2014

Quantitative imaging of serotonergic biosynthesis and degradation in the endocrine pancreas.

J Nucl Med 2014 Mar 13;55(3):460-5. Epub 2014 Feb 13.

Department of Medicinal Chemistry, Preclinical PET Platform, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.2967/jnumed.113.125187DOI Listing
March 2014

The immunosuppressive agents rapamycin, cyclosporin A and tacrolimus increase lipolysis, inhibit lipid storage and alter expression of genes involved in lipid metabolism in human adipose tissue.

Mol Cell Endocrinol 2013 Jan 15;365(2):260-9. Epub 2012 Nov 15.

The Lundberg Laboratory for Diabetes Research, Department of Molecular and Clinical Medicine, The Sahlgrenska Academy at University of Gothenburg, 413 45 Gothenburg, Sweden.

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http://dx.doi.org/10.1016/j.mce.2012.10.030DOI Listing
January 2013

mTOR inhibition with rapamycin causes impaired insulin signalling and glucose uptake in human subcutaneous and omental adipocytes.

Mol Cell Endocrinol 2012 May 8;355(1):96-105. Epub 2012 Feb 8.

The Lundberg Laboratory for Diabetes Research, Department of Molecular and Clinical Medicine, The Sahlgrenska Academy at University of Gothenburg, 413 45 Gothenburg, Sweden.

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https://linkinghub.elsevier.com/retrieve/pii/S03037207120005
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http://dx.doi.org/10.1016/j.mce.2012.01.024DOI Listing
May 2012

Novel pancreatic beta cell-specific proteins: antibody-based proteomics for identification of new biomarker candidates.

J Proteomics 2012 May 21;75(9):2611-20. Epub 2012 Mar 21.

Department of Immunology, Genetics and Pathology, Science for Life Laboratory, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.1016/j.jprot.2012.03.008DOI Listing
May 2012

Effects of adrenaline on whole-body glucose metabolism and insulin-mediated regulation of glycogen synthase and PKB phosphorylation in human skeletal muscle.

Metabolism 2011 Feb 12;60(2):215-26. Epub 2010 Feb 12.

Department of Physiology, National Institute of Occupational Health, P.O. Box 8149 Dep, N-0033 Oslo, Norway.

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http://linkinghub.elsevier.com/retrieve/pii/S002604950900547
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http://dx.doi.org/10.1016/j.metabol.2009.12.028DOI Listing
February 2011

Association of serum amyloid A levels with adipocyte size and serum levels of adipokines: differences between men and women.

Cytokine 2009 Dec 15;48(3):260-6. Epub 2009 Sep 15.

Sahlgrenska Center for Cardiovascular and Metabolic Research, Department of Molecular and Clinical Medicine, Institute of Medicine, The Sahlgrenska Academy, Göteborg University, Göteborg, Sweden.

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http://dx.doi.org/10.1016/j.cyto.2009.08.005DOI Listing
December 2009

Effects of decavanadate and insulin enhancing vanadium compounds on glucose uptake in isolated rat adipocytes.

J Inorg Biochem 2009 Dec 26;103(12):1687-92. Epub 2009 Sep 26.

CCMAR and FCT, University of Algarve, Campus das Gambelas, 8005-139 Faro, Portugal.

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http://linkinghub.elsevier.com/retrieve/pii/S016201340900236
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http://dx.doi.org/10.1016/j.jinorgbio.2009.09.015DOI Listing
December 2009

Tissue plasminogen activator (tPA) activity is a novel and early marker of asymptomatic LEAD in type 2 diabetes.

Thromb Res 2009 Mar 21;123(5):701-6. Epub 2008 Oct 21.

Department of Medicine, Umeå University Hospital, Umeå, Sweden.

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http://linkinghub.elsevier.com/retrieve/pii/S004938480800356
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http://dx.doi.org/10.1016/j.thromres.2008.07.015DOI Listing
March 2009

The effect of polymorphisms in the renin-angiotensin-aldosterone system on diabetic nephropathy risk.

J Diabetes Complications 2008 Nov-Dec;22(6):377-83. Epub 2008 Apr 16.

Department of Clinical Sciences, Paediatrics, Umeå University, Umeå, Sweden.

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http://dx.doi.org/10.1016/j.jdiacomp.2007.06.005DOI Listing
January 2009

Neuroendocrine mechanisms in insulin resistance.

Mol Cell Endocrinol 2009 Jan 27;297(1-2):104-11. Epub 2008 May 27.

The Lundberg Laboratory for Diabetes Research, Department of Medicine, Sahlgrenska University Hospital, Gothenburg, Sweden.

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http://dx.doi.org/10.1016/j.mce.2008.05.010DOI Listing
January 2009

Fatty acid profile of the erythrocyte membrane preceding development of Type 2 diabetes mellitus.

Nutr Metab Cardiovasc Dis 2008 Sep 26;18(7):503-10. Epub 2007 Nov 26.

Behavioural Medicine, Department of Public Health and Clinical Medicine, Umeå University, SE-901 85 Umeå, Sweden.

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http://linkinghub.elsevier.com/retrieve/pii/S093947530700104
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http://dx.doi.org/10.1016/j.numecd.2007.04.005DOI Listing
September 2008

[Reply on new drugs against type 2 diabetes: important to gain experience and knowledge].

Lakartidningen 2008 Apr 23-May 6;105(17-18):1310, 1312

Karolinska institutet, Diabetescentrum, Södersjukhuset AB, Stockholm.

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June 2008

[Toe blood pressure measurement better than ankle blood pressure measurement in patients with diabetes].

Lakartidningen 2008 Mar 18-Apr 1;105(12-13):925-6

Sahlgrenska Universitetssjukhuset, Göteborg.

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May 2008

Metabolic stress in insulin's target cells leads to ROS accumulation - a hypothetical common pathway causing insulin resistance.

Authors:
Jan W Eriksson

FEBS Lett 2007 Jul 27;581(19):3734-42. Epub 2007 Jun 27.

The Lundberg Laboratory for Diabetes Research, Institute of Medicine, Sahlgrenska University Hospital, SE 41345 Gothenburg, Sweden.

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http://dx.doi.org/10.1016/j.febslet.2007.06.044DOI Listing
July 2007

Components of metabolic syndrome predicting diabetes: no role of inflammation or dyslipidemia.

Obesity (Silver Spring) 2007 Jul;15(7):1875-85

Epidemiology and Public Health Sciences Section, Department of Public Health and Clinical Medicine, Umea University Hospital, Building 9B, SE-901 85 Umea, Sweden.

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http://www.researchgate.net/profile/Margareta_Norberg/public
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http://doi.wiley.com/10.1038/oby.2007.222
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http://dx.doi.org/10.1038/oby.2007.222DOI Listing
July 2007

Insulin resistance induced by high glucose and high insulin precedes insulin receptor substrate 1 protein depletion in human adipocytes.

Metabolism 2007 Feb;56(2):190-8

Department of Public Health and Clinical Medicine, Medicine, Umeå University Hospital, S-901 85 Umeå, Sweden.

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http://linkinghub.elsevier.com/retrieve/pii/S002604950600346
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http://dx.doi.org/10.1016/j.metabol.2006.09.012DOI Listing
February 2007

Insulin resistance in diabetic nephropathy--cause or consequence?

Diabetes Metab Res Rev 2006 Sep-Oct;22(5):401-10

Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.

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http://dx.doi.org/10.1002/dmrr.648DOI Listing
November 2006

Is insulin resistance caused by defects in insulin's target cells or by a stressed mind?

Diabetes Metab Res Rev 2005 Nov-Dec;21(6):487-94

Department of Public Health and Clinical Medicine, Medicine, Umeå University Hospital, Umeå, Sweden.

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http://dx.doi.org/10.1002/dmrr.567DOI Listing
January 2006

Insulin receptor substrates-1 and -2 are both depleted but via different mechanisms after down-regulation of glucose transport in rat adipocytes.

Endocrinology 2005 Jul 21;146(7):3044-51. Epub 2005 Apr 21.

Department of Medicine, Umeå University Hospital, SE-901 85 Umeå, Sweden.

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http://dx.doi.org/10.1210/en.2004-1675DOI Listing
July 2005

Evaluation of simple non-invasive techniques for assessment of lower extremity arterial disease.

Clin Physiol Funct Imaging 2005 May;25(3):129-34

Department of Medicine, Umeå University Hospital, Sweden.

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http://dx.doi.org/10.1111/j.1475-097X.2005.00597.xDOI Listing
May 2005

Dysregulation of the autonomic nervous system can be a link between visceral adiposity and insulin resistance.

Obes Res 2005 Apr;13(4):717-28

Department of Medicine, Umeå University Hospital, S-901 85 Umeå, Sweden.

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http://doi.wiley.com/10.1038/oby.2005.81
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http://dx.doi.org/10.1038/oby.2005.81DOI Listing
April 2005

[Exciting findings can change the view on the pathogenesis of type 2 diabetes. Impaired mitochondrial function can explain metabolic disorders in several organs].

Authors:
Jan W Eriksson

Lakartidningen 2004 Sep;101(39):2992-3

Medicinkliniken, Norrlands Universitetssjukhus, Umeå.

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September 2004