Jan Voorberg

Jan Voorberg

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Jan Voorberg

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Tolerating Factor VIII: Recent Progress.

Front Immunol 2019 10;10:2991. Epub 2020 Jan 10.

Uniformed Services University of the Health Sciences, Bethesda, MD, United States.

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http://dx.doi.org/10.3389/fimmu.2019.02991DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6965068PMC
January 2020

Defective AP-3-dependent VAMP8 trafficking impairs Weibel-Palade body exocytosis in Hermansky-Pudlak Syndrome type 2 blood outgrowth endothelial cells.

Haematologica 2019 Oct 10;104(10):2091-2099. Epub 2019 Jan 10.

Molecular and Cellular Hemostasis, Sanquin Research and Landsteiner Laboratory, Amsterdam UMC, University of Amsterdam, Amsterdam

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http://www.haematologica.org/lookup/doi/10.3324/haematol.201
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http://dx.doi.org/10.3324/haematol.2018.207787DOI Listing
October 2019

Alternative trafficking of Weibel-Palade body proteins in CRISPR/Cas9-engineered von Willebrand factor-deficient blood outgrowth endothelial cells.

Res Pract Thromb Haemost 2019 Oct 1;3(4):718-732. Epub 2019 Aug 1.

Molecular and Cellular Hemostasis Sanquin Research and Landsteiner Laboratory Amsterdam UMC University of Amsterdam Amsterdam The Netherlands.

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http://dx.doi.org/10.1002/rth2.12242DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6782018PMC
October 2019

Interaction networks of Weibel-Palade body regulators syntaxin-3 and syntaxin binding protein 5 in endothelial cells.

J Proteomics 2019 Aug 13;205:103417. Epub 2019 Jun 13.

Molecular and Cellular Hemostasis, Amsterdam UMC, University of Amsterdam, The Netherlands; Hematology, Erasmus University Medical Center, Rotterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.jprot.2019.103417DOI Listing
August 2019

Update - PROFILE: Early-Stage Researchers Advancing Insights on TTP through a Unique PhD Track.

Hemasphere 2019 Aug 7;3(4):e281. Epub 2019 Aug 7.

Laboratory for Thrombosis Research, IRF Life Sciences, KU Leuven Campus Kulak Kortrijk, Kortrijk, Belgium.

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http://dx.doi.org/10.1097/HS9.0000000000000281DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6745918PMC
August 2019

Emerging Concepts in Immune Thrombocytopenia.

Front Immunol 2018 30;9:880. Epub 2018 Apr 30.

Department of Hematology, Erasmus University Medical Centre, Rotterdam, Netherlands.

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http://dx.doi.org/10.3389/fimmu.2018.00880DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5937051PMC
June 2019

A subset of anti-HLA antibodies induces FcγRIIa-dependent platelet activation.

Haematologica 2018 10 1;103(10):1741-1752. Epub 2018 Jun 1.

Department of Immunohaematology and Blood Transfusion, Leiden University Medical Center, the Netherlands.

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http://dx.doi.org/10.3324/haematol.2018.189365DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6165798PMC
October 2018

Inhibitors in Nonsevere Hemophilia A: What Is Known and Searching for the Unknown.

Semin Thromb Hemost 2018 Sep 13;44(6):568-577. Epub 2018 Feb 13.

Department of Oncology, Center for Bleeding Disorders and Coagulation, Careggi University Hospital, Firenze, Italy.

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http://dx.doi.org/10.1055/s-0037-1621717DOI Listing
September 2018

Dissecting the pathophysiology of immune thrombotic thrombocytopenic purpura: interplay between genes and environmental triggers.

Haematologica 2018 07 19;103(7):1099-1109. Epub 2018 Apr 19.

Centre de Référence des Microangiopathies Thrombotiques, Hôpital Saint-Antoine, AP-HP, Paris, France

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http://dx.doi.org/10.3324/haematol.2016.151407DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6029525PMC
July 2018

Weibel-Palade Body Localized Syntaxin-3 Modulates Von Willebrand Factor Secretion From Endothelial Cells.

Arterioscler Thromb Vasc Biol 2018 07 7;38(7):1549-1561. Epub 2018 Jun 7.

From the Plasma Proteins, Sanquin Research and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, The Netherlands (M.S., E.K., B.L.v.d.E., A.G., M.H., D.v.B., H.M., M.v.d.B., J.V., R.B.)

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http://dx.doi.org/10.1161/ATVBAHA.117.310701DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6039413PMC
July 2018

Mass spectrometry-assisted identification of ADAMTS13-derived peptides presented on HLA-DR and HLA-DQ.

Haematologica 2018 06 22;103(6):1083-1092. Epub 2018 Mar 22.

Department of Plasma Proteins, Sanquin Research and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, the Netherlands.

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http://dx.doi.org/10.3324/haematol.2017.179119DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6058777PMC
June 2018

Desmopressin in moderate hemophilia A patients: a treatment worth considering.

Haematologica 2018 03 5;103(3):550-557. Epub 2018 Jan 5.

Department of Pediatric Hematology, Immunology and Infectious diseases, Emma Children's Hospital, Amsterdam, the Netherlands

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http://dx.doi.org/10.3324/haematol.2017.180059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5830393PMC
March 2018

Comparative profiling of HLA-DR and HLA-DQ associated factor VIII peptides presented by monocyte-derived dendritic cells.

Haematologica 2018 01 12;103(1):172-178. Epub 2017 Oct 12.

Department of Plasma Proteins, Sanquin Research and Landsteiner Laboratory, Academic Medical Center, University of Amsterdam, the Netherlands

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http://dx.doi.org/10.3324/haematol.2017.175083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777204PMC
January 2018

Insights into 3D Structure of ADAMTS13: A Stepping Stone towards Novel Therapeutic Treatment of Thrombotic Thrombocytopenic Purpura.

Thromb Haemost 2018 01 5;118(1):28-41. Epub 2018 Jan 5.

Department of Biochemistry, Cardiovascular Research Institute Maastricht (CARIM), Maastricht University, Maastricht, The Netherlands.

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http://dx.doi.org/10.1160/TH17-06-0404DOI Listing
January 2018

To serve and protect: The modulatory role of von Willebrand factor on factor VIII immunogenicity.

Blood Rev 2017 09 4;31(5):339-347. Epub 2017 Jul 4.

Department of Plasma Proteins, Sanquin Research, Plesmanlaan 125, 1066 CX Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.blre.2017.07.001DOI Listing
September 2017

Platelet-independent adhesion of calcium-loaded erythrocytes to von Willebrand factor.

PLoS One 2017 1;12(3):e0173077. Epub 2017 Mar 1.

Department of Molecular Cell Biology, Sanquin-Academic Medical Center Landsteiner Laboratory, Amsterdam, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0173077PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5332109PMC
August 2017

Analysis of the HLA-DR peptidome from human dendritic cells reveals high affinity repertoires and nonconventional pathways of peptide generation.

J Leukoc Biol 2017 01 30;101(1):15-27. Epub 2016 Jun 30.

Department of Cell Biology, Physiology and Immunology, Laboratori d'Immunologia Cellular, Institut de Biotecnologia i Biomedicina, Universitat Autònoma de Barcelona, Barcelona, Spain;

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http://dx.doi.org/10.1189/jlb.6HI0216-069RDOI Listing
January 2017

The class I scavenger receptor CD163 promotes internalization of ADAMTS13 by macrophages.

Blood Adv 2017 Jan 16;1(5):293-305. Epub 2017 Jan 16.

Department of Plasma Proteins, Sanquin Research and Landsteiner Laboratory, Academic Medical Center (AMC), University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1182/bloodadvances.2016001321DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5744037PMC
January 2017

Identification of glycans on plasma-derived ADAMTS13.

Blood 2016 11 29;128(21):e51-e58. Epub 2016 Aug 29.

Department of Plasma Proteins, Sanquin-Academic Medical Center Landsteiner Laboratory, Amsterdam, The Netherlands.

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http://www.bloodjournal.org/content/early/2016/08/29/blood-2
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http://dx.doi.org/10.1182/blood-2016-06-720912DOI Listing
November 2016

Up or out: polarity of VWF release.

Blood 2016 07;128(2):154-5

SANQUIN-AMC LANDSTEINER LABORATORY.

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http://dx.doi.org/10.1182/blood-2016-05-713057DOI Listing
July 2016

Hunting down factor VIII in the immunopeptidome.

Cell Immunol 2016 Mar 5;301:59-64. Epub 2015 Nov 5.

Department of Plasma Proteins, Sanquin-AMC Landsteiner Laboratory, Amsterdam, The Netherlands. Electronic address:

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http://dx.doi.org/10.1016/j.cellimm.2015.11.001DOI Listing
March 2016

Individual with subclinical atherosclerosis have impaired proliferation of blood outgrowth endothelial cells, which can be restored by statin therapy.

PLoS One 2014 23;9(6):e99890. Epub 2014 Jun 23.

Department of Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands; Department of Clinical Epidemiology, Biostatistics and Bioinformatics, Academic Medical Center, Amsterdam, The Netherlands.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0099890PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4067291PMC
October 2015

Disappearing acts of ADAMTS13.

EBioMedicine 2015 Aug 10;2(8):800-1. Epub 2015 Jul 10.

Department of Haematology, University Medical Centre Utrecht, Utrecht, The Netherlands.

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http://dx.doi.org/10.1016/j.ebiom.2015.07.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4563130PMC
August 2015

Content delivery to newly forming Weibel-Palade bodies is facilitated by multiple connections with the Golgi apparatus.

Blood 2015 May 25;125(22):3509-16. Epub 2015 Feb 25.

Department of Thrombosis and Hemostasis, Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, Leiden, The Netherlands.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2014-10-60
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http://dx.doi.org/10.1182/blood-2014-10-608596DOI Listing
May 2015

Storage and secretion of naturally occurring von Willebrand factor A domain variants.

Br J Haematol 2014 Nov 8;167(4):529-40. Epub 2014 Aug 8.

Einthoven Laboratory for Experimental Vascular Medicine, Department of Thrombosis and Hemostasis, Leiden University Medical Centre, Leiden, The Netherlands.

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http://dx.doi.org/10.1111/bjh.13074DOI Listing
November 2014

Acquired TTP: ADAMTS13 meets the immune system.

Blood Rev 2014 Nov 15;28(6):227-34. Epub 2014 Aug 15.

Department of Plasma Proteins, Sanquin-AMC Landsteiner Laboratory, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.blre.2014.07.004DOI Listing
November 2014

STXBP1 promotes Weibel-Palade body exocytosis through its interaction with the Rab27A effector Slp4-a.

Blood 2014 May 3;123(20):3185-94. Epub 2014 Apr 3.

Plasma Proteins, Sanquin-Academisch Medisch Centrum Landsteiner Laboratory, Amsterdam, The Netherlands; Physical Biochemistry, Medical Research Council National Institute for Medical Research, London, United Kingdom;

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2013-10-53
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http://dx.doi.org/10.1182/blood-2013-10-535831DOI Listing
May 2014

Decrypting C2 inhibitors.

Blood 2014 Apr;123(17):2601-2

SANQUIN-ACADEMIC MEDICAL CENTER LANDSTEINER LABORATORY.

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http://dx.doi.org/10.1182/blood-2014-03-562165DOI Listing
April 2014

Rational design of small molecules targeting the C2 domain of coagulation factor VIII.

Blood 2014 Jan 13;123(1):113-20. Epub 2013 Nov 13.

Department of Biochemistry, Cardiovascular Research Institute Maastricht, Maastricht University, The Netherlands;

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http://dx.doi.org/10.1182/blood-2013-05-503227DOI Listing
January 2014

Altered glycosylation of platelet-derived von Willebrand factor confers resistance to ADAMTS13 proteolysis.

Blood 2013 Dec 8;122(25):4107-10. Epub 2013 Oct 8.

Haemostasis Research Group, Institute of Molecular Medicine, Trinity Centre for Health Sciences, St James's Hospital, Trinity College Dublin, Ireland;

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http://dx.doi.org/10.1182/blood-2013-04-496851DOI Listing
December 2013

Preferential HLA-DRB1*11-dependent presentation of CUB2-derived peptides by ADAMTS13-pulsed dendritic cells.

Blood 2013 Apr 31;121(17):3502-10. Epub 2013 Jan 31.

Department of Plasma Proteins, Sanquin Research, Plesmanlaan 125, Amsterdam, the Netherlands.

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http://dx.doi.org/10.1182/blood-2012-09-456780DOI Listing
April 2013

Analysis of the storage and secretion of von Willebrand factor in blood outgrowth endothelial cells derived from patients with von Willebrand disease.

Blood 2013 Apr 20;121(14):2762-72. Epub 2013 Feb 20.

Einthoven Laboratory for Experimental Vascular Medicine, Department of Thrombosis and Hemostasis, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1182/blood-2012-06-434373DOI Listing
April 2013

Effect of laminar shear stress on the distribution of Weibel-Palade bodies in endothelial cells.

Thromb Res 2012 Nov 7;130(5):741-5. Epub 2012 Sep 7.

Department of Plasma Proteins, Sanquin-AMC Landsteiner Laboratory, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.thromres.2012.08.301DOI Listing
November 2012

Establishment of outgrowth endothelial cells from peripheral blood.

Nat Protoc 2012 Sep 23;7(9):1709-15. Epub 2012 Aug 23.

Department of Plasma Proteins, Landsteiner Laboratory, Academic Medical Centre and Sanquin, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1038/nprot.2012.093DOI Listing
September 2012

The Epac-Rap1 signaling pathway controls cAMP-mediated exocytosis of Weibel-Palade bodies in endothelial cells.

J Biol Chem 2012 Jul 16;287(29):24713-20. Epub 2012 Apr 16.

Department of Plasma Proteins, Sanquin Research and Landsteiner Laboratory Amsterdam Medical Center, 1066 CX Amsterdam, The Netherlands.

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http://dx.doi.org/10.1074/jbc.M111.321976DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3397898PMC
July 2012

Biogenesis of Weibel-Palade bodies in von Willebrand's disease variants with impaired von Willebrand factor intrachain or interchain disulfide bond formation.

Haematologica 2012 Jun 29;97(6):859-66. Epub 2011 Dec 29.

Einthoven Laboratory for Experimental Vascular Medicine, Department of Thrombosis and Hemostasis, Leiden University Medical Center, The Netherlands.

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http://dx.doi.org/10.3324/haematol.2011.057216DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366651PMC
June 2012

Long-term expression of human coagulation factor VIII in a tolerant mouse model using the φC31 integrase system.

Hum Gene Ther 2012 Apr 26;23(4):390-8. Epub 2012 Jan 26.

Department of Genetics, Stanford University School of Medicine, Stanford, CA 94305-5120, USA.

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http://dx.doi.org/10.1089/hum.2011.110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3327602PMC
April 2012

The macrophage mannose receptor promotes uptake of ADAMTS13 by dendritic cells.

Blood 2012 Apr 30;119(16):3828-35. Epub 2012 Jan 30.

Department of Plasma Proteins, Sanquin-Academic Medical Center Landsteiner Laboratory, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1182/blood-2011-09-377754DOI Listing
April 2012

Improving on nature: redesigning ADAMTS13.

Blood 2012 Apr;119(16):3654-5

Bern University Hospital, Switzerland.

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http://dx.doi.org/10.1182/blood-2012-02-410431DOI Listing
April 2012

Uptake of blood coagulation factor VIII by dendritic cells is mediated via its C1 domain.

J Allergy Clin Immunol 2012 Feb 1;129(2):501-9, 509.e1-5. Epub 2011 Oct 1.

Department of Plasma Proteins, Sanquin-AMC Landsteiner Laboratory, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.jaci.2011.08.029DOI Listing
February 2012

Requirements for immune recognition and processing of factor VIII by antigen-presenting cells.

Blood Rev 2012 Jan 26;26(1):43-9. Epub 2011 Oct 26.

Department of Plasma Proteins, Sanquin-AMC Landsteiner Laboratory and Van Creveld Laboratory, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.blre.2011.10.001DOI Listing
January 2012

Residues Arg568 and Phe592 contribute to an antigenic surface for anti-ADAMTS13 antibodies in the spacer domain.

Haematologica 2011 Nov 28;96(11):1670-7. Epub 2011 Jun 28.

Department of Plasma Proteins, Sanquin-AMC Landsteiner Laboratory, Amsterdam, the Netherlands.

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http://dx.doi.org/10.3324/haematol.2010.036327DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208685PMC
November 2011

Factor VIII alters tubular organization and functional properties of von Willebrand factor stored in Weibel-Palade bodies.

Blood 2011 Nov 22;118(22):5947-56. Epub 2011 Sep 22.

Department of Plasma Proteins, Sanquin Research, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1182/blood-2011-05-355354DOI Listing
November 2011

Essential domains of a disintegrin and metalloprotease with thrombospondin type 1 repeats-13 metalloprotease required for modulation of arterial thrombosis.

Arterioscler Thromb Vasc Biol 2011 Oct 28;31(10):2261-9. Epub 2011 Jul 28.

Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, PA 19104, USA.

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http://dx.doi.org/10.1161/ATVBAHA.111.229609DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3174348PMC
October 2011

Intracellular storage and regulated secretion of von Willebrand factor in quantitative von Willebrand disease.

J Biol Chem 2011 Jul 19;286(27):24180-8. Epub 2011 May 19.

Einthoven Laboratory for Experimental Vascular Medicine, Leiden University Medical Center, 2333ZA Leiden, The Netherlands.

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http://dx.doi.org/10.1074/jbc.M110.215194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3129199PMC
July 2011

HLA-DR-presented peptide repertoires derived from human monocyte-derived dendritic cells pulsed with blood coagulation factor VIII.

Mol Cell Proteomics 2011 Jun 5;10(6):M110.002246. Epub 2011 Apr 5.

Department of Plasma Proteins, Van Creveld Laboratory of UMC Utrecht and Sanquin Research, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1074/mcp.M110.002246DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3108829PMC
June 2011

Functional architecture of Weibel-Palade bodies.

Blood 2011 May 25;117(19):5033-43. Epub 2011 Jan 25.

Department of Molecular Cell Biology, Section Electron Microscopy, Leiden University Medical Center, Leiden, The Netherlands.

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http://dx.doi.org/10.1182/blood-2010-09-267492DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3109530PMC
May 2011

Getting rid of bad memory.

Blood 2011 Jan;117(1):7-8

Sanquin-AMC Landsteiner Laboratory.

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http://dx.doi.org/10.1182/blood-2010-10-312124DOI Listing
January 2011

Storage and regulated secretion of factor VIII in blood outgrowth endothelial cells.

Haematologica 2009 May 31;94(5):670-8. Epub 2009 Mar 31.

Department of Plasma Proteins, Sanquin Research, Plesmanlaan 125, Amsterdam, The Netherlands.

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http://dx.doi.org/10.3324/haematol.13427DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2675679PMC
May 2009

Intracellular cotrafficking of factor VIII and von Willebrand factor type 2N variants to storage organelles.

Blood 2009 Mar 16;113(13):3102-9. Epub 2008 Dec 16.

Department of Plasma Proteins, Sanquin Research, Amsterdam, The Netherlands.

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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2008-05-15
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http://dx.doi.org/10.1182/blood-2008-05-159699DOI Listing
March 2009

IgG subclasses of anti-FVIII antibodies during immune tolerance induction in patients with hemophilia A.

Br J Haematol 2008 Aug 28;142(4):644-52. Epub 2008 May 28.

Department of Plasma Proteins, Van Creveld Laboratorium and Landsteiner Laboratorium of the AMC at Sanquin Research, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1111/j.1365-2141.2008.07232.xDOI Listing
August 2008

Guanine exchange factor RalGDS mediates exocytosis of Weibel-Palade bodies from endothelial cells.

Blood 2008 Jul 16;112(1):56-63. Epub 2008 Apr 16.

Department of Plasma Proteins, Sanquin Research and Landsteiner Laboratory Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1182/blood-2007-07-099309DOI Listing
July 2008

Slipping out the Weibel-Palade body.

Authors:
Jan Voorberg

Blood 2008 Jun;111(11):5264-5

Sanquin-AMC Landsteiner Laboratory.

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http://dx.doi.org/10.1182/blood-2008-02-138990DOI Listing
June 2008

Antibodies against the CUB1-2 domains of ADAMTS13 in a patient with benign monoclonal gammopathy: no causal relationship.

Haematologica 2007 Jul;92(7):e74-6

Department of Internal Medicine, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands.

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http://dx.doi.org/10.3324/haematol.11475DOI Listing
July 2007

Differential effects of the loss of intrachain- versus interchain-disulfide bonds in the cystine-knot domain of von Willebrand factor on the clinical phenotype of von Willebrand disease.

Thromb Haemost 2006 Dec;96(6):717-24

Hemostasis and Thrombosis Research Center, Department of Hematology, C2-R, Leiden University Medical Center, PO Box 9600, 2300 RC Leiden, the Netherlands.

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http://dx.doi.org/10.1160/th06-08-0460DOI Listing
December 2006

KLF2 provokes a gene expression pattern that establishes functional quiescent differentiation of the endothelium.

Blood 2006 Jun 2;107(11):4354-63. Epub 2006 Feb 2.

Department of Medical Biochemistry, Academic Medical Center, University of Amsterdam, Meibergdreef 15, 1105 AZ Amsterdam, The Netherlands.

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http://dx.doi.org/10.1182/blood-2005-08-3465DOI Listing
June 2006

Dynamics and plasticity of Weibel-Palade bodies in endothelial cells.

Arterioscler Thromb Vasc Biol 2006 May 9;26(5):1002-7. Epub 2006 Feb 9.

Department of Plasma Proteins, AMC, University of Amsterdam, Amsterdam.

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https://www.ahajournals.org/doi/10.1161/01.ATV.0000209501.56
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http://dx.doi.org/10.1161/01.ATV.0000209501.56852.6cDOI Listing
May 2006

Dynein-dynactin complex mediates protein kinase A-dependent clustering of Weibel-Palade bodies in endothelial cells.

Arterioscler Thromb Vasc Biol 2006 Jan 20;26(1):49-55. Epub 2005 Oct 20.

Department of Plasma Proteins, Sanquin Research, University of Amsterdam, The Netherlands.

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http://dx.doi.org/10.1161/01.ATV.0000191639.08082.04DOI Listing
January 2006

Phospholipid vesicles interfere with the binding of antibody fragments to the light chain of factor VIII.

Thromb Haemost 2005 May;93(5):833-41

Division of Hematology, Department of Medicine, Duke University Medical Center, Durham, NC 27710, USA.

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http://dx.doi.org/10.1160/TH04-11-0729DOI Listing
May 2005

The spacer domain of ADAMTS13 contains a major binding site for antibodies in patients with thrombotic thrombocytopenic purpura.

Thromb Haemost 2005 Feb;93(2):267-74

Department of Plasma Proteins, Sanquin Research at CLB, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1160/TH04-05-0301DOI Listing
February 2005

Small GTP-binding protein Ral is involved in cAMP-mediated release of von Willebrand factor from endothelial cells.

Arterioscler Thromb Vasc Biol 2004 Jul 6;24(7):1315-20. Epub 2004 May 6.

Department of Plasma Proteins, Sanquin Research at CLB, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1161/01.ATV.0000131267.13425.45DOI Listing
July 2004

Real-time imaging of the dynamics and secretory behavior of Weibel-Palade bodies.

Arterioscler Thromb Vasc Biol 2003 May 3;23(5):755-61. Epub 2003 Apr 3.

Department of Plasma Proteins, Sanquin Research at CLB, Plesmanlaan 125, 1066 CX Amsterdam, The Netherlands.

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http://dx.doi.org/10.1161/01.ATV.0000069847.72001.E8DOI Listing
May 2003

Von Willebrand factor targets IL-8 to Weibel-Palade bodies in an endothelial cell line.

Exp Cell Res 2003 May;286(1):67-74

Department of Plasma Proteins and Blood Coagulation, CLB, Plesmanlaan 125, 1066 CX Amsterdam, The Netherlands.

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http://dx.doi.org/10.1016/s0014-4827(03)00094-6DOI Listing
May 2003

Low density lipoprotein receptor-related protein and factor IXa share structural requirements for binding to the A3 domain of coagulation factor VIII.

J Biol Chem 2003 Mar 8;278(11):9370-7. Epub 2003 Jan 8.

Department of Plasma Proteins, Sanquin Research at CLB, 1066 CX Amsterdam, The Netherlands.

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http://dx.doi.org/10.1074/jbc.M212053200DOI Listing
March 2003

Immunobiology of inhibitor development in hemophilia A.

Semin Thromb Hemost 2003 Feb;29(1):61-8

Department of Pediatrics, Emma Children's Hospital, Academic Medical Center, University of Amsterdam, The Netherlands.

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http://dx.doi.org/10.1055/s-2003-37940DOI Listing
February 2003

Analysis of factor VIII inhibitors in a haemophilia A patient with an Arg593-->Cys mutation using phage display.

Br J Haematol 2002 Nov;119(2):393-6

Department of Plasma Proteins, Sanquin Research at CLB, Emma Children's Hospital, Academic Medical Centre, University of Amsterdam, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1046/j.1365-2141.2002.03856.xDOI Listing
November 2002

Biogenesis and exocytosis of Weibel-Palade bodies.

Histochem Cell Biol 2002 Feb 19;117(2):113-22. Epub 2002 Jan 19.

Department of Blood Coagulation, CLB, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00418-001-0368-9DOI Listing
February 2002