Publications by authors named "Jan Tuckermann"

100Publications

RNF40 exerts stage-dependent functions in differentiating osteoblasts and is essential for bone cell crosstalk.

Cell Death Differ 2020 Sep 8. Epub 2020 Sep 8.

Institute of Comparative Molecular Endocrinology, University of Ulm, Helmholtzstrasse 8/1, 89081, Ulm, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41418-020-00614-wDOI Listing
September 2020

Author Correction: Glucocorticoids suppress Wnt16 expression in osteoblasts in vitro and in vivo.

Sci Rep 2020 Jun 4;10(1):9344. Epub 2020 Jun 4.

Division of Endocrinology, Diabetes, and Bone Diseases, Department of Medicine III, Technische Universität Dresden, Dresden, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-020-65962-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271193PMC
June 2020

PPARδ-mediated mitochondrial rewiring of osteoblasts determines bone mass.

Sci Rep 2020 05 21;10(1):8428. Epub 2020 May 21.

Department of Internal Medicine 3, Rheumatology and Immunology, Friedrich Alexander University Erlangen-Nurnberg and Universitätsklinikum Erlangen, Erlangen, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-020-65305-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7242479PMC
May 2020

Massive osteopetrosis caused by non-functional osteoclasts in R51Q SNX10 mutant mice.

Bone 2020 Jul 8;136:115360. Epub 2020 Apr 8.

Department of Molecular Genetics, The Weizmann Institute of Science, Rehovot 76100, Israel. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bone.2020.115360DOI Listing
July 2020

A Jack of All Trades: Impact of Glucocorticoids on Cellular Cross-Talk in Osteoimmunology.

Front Immunol 2019 17;10:2460. Epub 2019 Oct 17.

Institute of Comparative Molecular Endocrinology (CME), University of Ulm, Ulm, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fimmu.2019.02460DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6811614PMC
October 2019

Glucocorticoids employ the monomeric glucocorticoid receptor to potentiate vitamin D and parathyroid hormone-induced osteoclastogenesis.

FASEB J 2019 12 14;33(12):14394-14409. Epub 2019 Nov 14.

Center for Bone and Arthritis Research, Institute for Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1096/fj.201802729RRRDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6894088PMC
December 2019

Despite Genetic Iron Overload, -Hemochromatosis Mice Do Not Show Bone Loss.

JBMR Plus 2019 Sep 26;3(9):e10206. Epub 2019 Jul 26.

Institute of Comparative Molecular Endocrinology, University of Ulm Ulm Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jbm4.10206DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6808227PMC
September 2019

Fighting the Fire: Mechanisms of Inflammatory Gene Regulation by the Glucocorticoid Receptor.

Front Immunol 2019 7;10:1859. Epub 2019 Aug 7.

Department of Biology, Institute for Comparative Molecular Endocrinology, University of Ulm, Ulm, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fimmu.2019.01859DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6693390PMC
October 2020

Glucocorticoids Shape Macrophage Phenotype for Tissue Repair.

Front Immunol 2019 9;10:1591. Epub 2019 Jul 9.

Institut NeuroMyoGène, Université Claude Bernard Lyon 1, Univ Lyon, CNRS UMR 5310, INSERM U1217, Lyon, France.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.3389/fimmu.2019.01591DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6632423PMC
October 2020

Osteoblast-derived NOTUM reduces cortical bone mass in mice and the locus is associated with bone mineral density in humans.

FASEB J 2019 10 15;33(10):11163-11179. Epub 2019 Jul 15.

Department of Internal Medicine and Clinical Nutrition, Institute of Medicine, Centre for Bone and Arthritis Research at the Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1096/fj.201900707RDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6766646PMC
October 2019

Phosphorylation of the phosphatase PTPROt at Tyr is a molecular switch that controls osteoclast activity and bone mass in vivo.

Sci Signal 2019 01 8;12(563). Epub 2019 Jan 8.

Department of Molecular Genetics, Weizmann Institute of Science, Rehovot 76100, Israel.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1126/scisignal.aau0240DOI Listing
January 2019

Insulin signaling and reduced glucocorticoid receptor activity attenuate postprandial gene expression in liver.

PLoS Biol 2018 12 10;16(12):e2006249. Epub 2018 Dec 10.

Department of Biochemistry and Molecular Biology, VILLUM Center for Bioanalytical Sciences, University of Southern Denmark, Odense, Denmark.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1371/journal.pbio.2006249DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6301715PMC
December 2018

Cell-based RNAi screening and high-content analysis in primary calvarian osteoblasts applied to identification of osteoblast differentiation regulators.

Sci Rep 2018 09 19;8(1):14045. Epub 2018 Sep 19.

Institute of Comparative Molecular Endocrinology (CME), Ulm University, Helmholtzstrasse 8/1, 89081, Ulm, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-018-32364-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145911PMC
September 2018

New horizons for osteoanabolic treatment?

Nat Rev Endocrinol 2018 09;14(9):508-509

Institute of Comparative Molecular Endocrinology, University of Ulm, Ulm, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41574-018-0069-2DOI Listing
September 2018

Liver Cancer Initiation Requires p53 Inhibition by CD44-Enhanced Growth Factor Signaling.

Cancer Cell 2018 06;33(6):1061-1077.e6

Laboratory of Gene Regulation and Signal Transduction, Department of Pharmacology, University of California San Diego, School of Medicine, 9500 Gilman Drive, San Diego, CA 92093, USA; Department of Pathology, University of California San Diego, School of Medicine, 9500 Gilman Drive, San Diego, CA 92093, USA; Moores Cancer Center, University of California San Diego, School of Medicine, 9500 Gilman Drive, La Jolla, CA 92093-0723, USA. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.ccell.2018.05.003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6005359PMC
June 2018

Glucocorticoids suppress Wnt16 expression in osteoblasts in vitro and in vivo.

Sci Rep 2018 06 7;8(1):8711. Epub 2018 Jun 7.

Division of Endocrinology, Diabetes, and Bone Diseases, Department of Medicine III, Technische Universität Dresden, Dresden, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41598-018-26300-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992207PMC
June 2018

The glucocorticoid receptor in recipient cells keeps cytokine secretion in acute graft-versus-host disease at bay.

Oncotarget 2018 Mar 2;9(21):15437-15450. Epub 2018 Mar 2.

Institute for Cellular and Molecular Immunology, University Medical Center, Georg-August-University Göttingen, Göttingen, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.18632/oncotarget.24602DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5884639PMC
March 2018

Molecular mechanisms of glucocorticoids on skeleton and bone regeneration after fracture.

J Mol Endocrinol 2018 07 27;61(1):R75-R90. Epub 2018 Mar 27.

Institute of Comparative Molecular EndocrinologyUlm University, Ulm, Germany

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1530/JME-18-0024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5976078PMC
July 2018

EGFR controls bone development by negatively regulating mTOR-signaling during osteoblast differentiation.

Cell Death Differ 2018 06 14;25(6):1094-1106. Epub 2018 Feb 14.

Department of Internal Medicine I, Institute of Cancer Research, Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/s41418-017-0054-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5988706PMC
June 2018

Estrogen receptor α- (ERα), but not ERβ-signaling, is crucially involved in mechanostimulation of bone fracture healing by whole-body vibration.

Bone 2018 05 3;110:11-20. Epub 2018 Feb 3.

Institute of Orthopedic Research and Biomechanics, University Medical Center Ulm, Helmholtzstraße 14, 89081 Ulm, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bone.2018.01.017DOI Listing
May 2018

Induced global deletion of glucocorticoid receptor impairs fracture healing.

FASEB J 2018 04 5;32(4):2235-2245. Epub 2018 Jan 5.

Institute of Orthopaedic Research and Biomechanics, Centre for Trauma Research Ulm, Ulm University Medical Centre.

View Article

Download full-text PDF

Source
http://www.fasebj.org/doi/10.1096/fj.201700459RR
Publisher Site
http://dx.doi.org/10.1096/fj.201700459RRDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5893166PMC
April 2018

Molecular Integration of Incretin and Glucocorticoid Action Reverses Immunometabolic Dysfunction and Obesity.

Cell Metab 2017 Oct 21;26(4):620-632.e6. Epub 2017 Sep 21.

Institute for Diabetes and Obesity, Helmholtz Diabetes Center, Helmholtz Zentrum München, 85764 Neuherberg, Germany; Division of Metabolic Diseases, Department of Medicine, Technische Universität München, 80333 Munich, Germany; German Center for Diabetes Research (DZD), Helmholtz Zentrum München, Ingolstädter Landstraße, 85764 Neuherberg, Germany. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.cmet.2017.08.023DOI Listing
October 2017

Endogenous glucocorticoid signaling in chondrocytes attenuates joint inflammation and damage.

FASEB J 2018 01 19;32(1):478-487. Epub 2017 Sep 19.

Bone Research Program, Australian and New Zealand Army Corps (ANZAC) Research Institute, Sydney, New South Wales, Australia;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1096/fj.201700659RDOI Listing
January 2018

Airway Epithelial Cells Are Crucial Targets of Glucocorticoids in a Mouse Model of Allergic Asthma.

J Immunol 2017 07 17;199(1):48-61. Epub 2017 May 17.

Institute for Cellular and Molecular Immunology, University Medical Center Göttingen, 37073 Göttingen, Germany;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1601691DOI Listing
July 2017

Activation of dimeric glucocorticoid receptors in osteoclast progenitors potentiates RANKL induced mature osteoclast bone resorbing activity.

Bone 2016 12 2;93:43-54. Epub 2016 Sep 2.

Centre for Bone and Arthritis Research at Department of Internal Medicine and Clinical Nutrition, Institute for Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden; Department of Molecular Periodontology, Umeå University, Umeå, Sweden. Electronic address:

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.bone.2016.08.024DOI Listing
December 2016

Molecular Actions of Glucocorticoids in Cartilage and Bone During Health, Disease, and Steroid Therapy.

Physiol Rev 2016 Apr;96(2):409-47

Institute for Comparative Molecular Endocrinology, University of Ulm, Ulm, Germany; and Division of Endocrinology, Diabetes, and Bone Diseases, Department of Medicine III, Technische Universität Dresden, Dresden, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1152/physrev.00011.2015DOI Listing
April 2016

Selepressin in Septic Shock: A Step Toward Decatecholaminization?

Crit Care Med 2016 Jan;44(1):234-6

Département de Réanimation Médicale et de Médecine Hyperbare, Centre Hospitalier Universitaire, Angers, FranceCenter for Heart Lung Innovation, Division of Critical Care Medicine, St. Paul's Hospital, University of British Columbia, Vancouver, BC, CanadaInstitut für Molekulare Endokrinologie der Tiere, Universität Ulm, Ulm, GermanyInstitut für Anästhesiologische Pathophysiologie und Verfahrensentwicklung, Universitätsklinikum, Ulm, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/CCM.0000000000001441DOI Listing
January 2016

Glucocorticoid-Induced Osteoporosis.

Adv Exp Med Biol 2015 ;872:179-215

Department of Orthopaedic Surgery, Keck School of Medicine, Institute for Genetic Medicine, University of Southern California, 2250 Alcazar Street, CSC-240, Los Angeles, CA, 90033, USA,

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1007/978-1-4939-2895-8_8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5905346PMC
October 2015

Genomic redistribution of GR monomers and dimers mediates transcriptional response to exogenous glucocorticoid in vivo.

Genome Res 2015 Jun 8;25(6):836-44. Epub 2015 May 8.

The Institute for Diabetes, Obesity, and Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA; Division of Endocrinology, Diabetes, and Metabolism, Department of Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1101/gr.188581.114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448680PMC
June 2015

ACTH controls thymocyte homeostasis independent of glucocorticoids.

FASEB J 2015 Jun 2;29(6):2526-34. Epub 2015 Mar 2.

*Department of Biosciences and Nutrition, Karolinska Institutet, Novum, Huddinge, Sweden; and Institute for Comparative Molecular Endocrinology, University of Ulm, Ulm, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1096/fj.14-268508DOI Listing
June 2015

Glucocorticoids induce gastroparesis in mice through depletion of l-arginine.

Endocrinology 2014 Oct 24;155(10):3899-908. Epub 2014 Jul 24.

Institute for Cellular and Molecular Immunology (S.D.R., T.W., M.O., J.v.d.B., H.M.R.) and Department of Neuroimmunology (F.L.), Institute for Multiple Sclerosis Research, The Hertie Foundation and MPI for Experimental Medicine, University of Göttingen Medical School, 37073 Göttingen, Germany; Institute of Physiology (A.R., M.F., F.L.), University of Tübingen, 72076 Tübingen, Germany; and Institute of General Zoology and Endocrinology (J.P.T.), University of Ulm, 89081 Ulm, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/en.2014-1246DOI Listing
October 2014

Bronchial epithelial cells induce alternatively activated dendritic cells dependent on glucocorticoid receptor signaling.

J Immunol 2014 Aug 25;193(3):1475-84. Epub 2014 Jun 25.

Department of Infectious Diseases, Medical Microbiology and Hygiene, University Hospital Heidelberg, 69120 Heidelberg, Germany;

View Article

Download full-text PDF

Source
http://dx.doi.org/10.4049/jimmunol.1400446DOI Listing
August 2014

Glucocorticoid receptor in prostate epithelia is not required for corticosteroid-induced epithelial hyperproliferation in the mouse prostate.

Prostate 2014 Jul 23;74(10):1068-78. Epub 2014 May 23.

Andrology, ANZAC Research Institute, University of Sydney, Sydney, NSW, Australia.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/pros.22825DOI Listing
July 2014

Steroids and vasopressin in septic shock-brother and sister or just distant cousins?

Crit Care Med 2014 Jun;42(6):1531-2

Département de Réanimation Médicale et de Médecine Hyperbare, Centre Hospitalier Universitaire, Angers, France Institut für Allgemeine Zoologie und Endokrinologie, Universität Ulm, Ulm, Germany Sektion Anästhesiologische Pathophysiologie und Verfahrensentwicklung, Klinik für Anästhesiologie, Universitätsklinikum, Ulm, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1097/CCM.0000000000000262DOI Listing
June 2014

Effects of the selective glucocorticoid receptor modulator compound A on bone metabolism and inflammation in male mice with collagen-induced arthritis.

Endocrinology 2013 Oct 24;154(10):3719-28. Epub 2013 Jul 24.

PhD, Division of Endocrinology, Diabetes, and Bone Diseases, Department of Medicine III, Fetscherstraβe 74, D-01307 Dresden, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/en.2012-2221DOI Listing
October 2013

Molecular determinants of glucocorticoid actions in inflammatory joint diseases.

Mol Cell Endocrinol 2013 Nov 14;380(1-2):108-18. Epub 2013 Jun 14.

Institute of General Zoology and Endocrinology, University of Ulm, Zentrum für Biomedizinische Forschung, Helmholtzstraße 8/1, D-89081 Ulm, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.mce.2013.06.009DOI Listing
November 2013

Inflammatory monocytes and Fcγ receptor IV on osteoclasts are critical for bone destruction during inflammatory arthritis in mice.

Proc Natl Acad Sci U S A 2013 Jun 10;110(26):10729-34. Epub 2013 Jun 10.

Institute of Genetics, Department of Biology, University of Erlangen-Nürnberg, 91058 Erlangen, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1301001110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3696830PMC
June 2013

PPARβ/δ governs Wnt signaling and bone turnover.

Nat Med 2013 May 31;19(5):608-13. Epub 2013 Mar 31.

Department of Internal Medicine 3 and Institute for Clinical Immunology, University of Erlangen-Nürnberg, Erlangen, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nm.3146DOI Listing
May 2013

The transcription factor early B-cell factor 1 regulates bone formation in an osteoblast-nonautonomous manner.

FEBS Lett 2013 Mar 5;587(6):711-6. Epub 2013 Feb 5.

Department of Genetics and Development, Columbia University Medical Center, New York, NY 10032, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.febslet.2013.01.049DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3893662PMC
March 2013

New insights into the anti-inflammatory mechanisms of glucocorticoids: an emerging role for glucocorticoid-receptor-mediated transactivation.

Endocrinology 2013 Mar 5;154(3):993-1007. Epub 2013 Feb 5.

VIB-Department for Molecular Biomedical Research /Ugent, Technologiepark 927, Zwijnaarde 9052, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/en.2012-2045DOI Listing
March 2013

The multiple facets of glucocorticoid action in rheumatoid arthritis.

Nat Rev Rheumatol 2012 Nov 9;8(11):645-55. Epub 2012 Oct 9.

Leibniz Institute for Age Research, Fritz Lipmann Institute, Beutenbergstraße 11, D-07745 Jena, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1038/nrrheum.2012.166DOI Listing
November 2012

Liver X receptors orchestrate osteoblast/osteoclast crosstalk and counteract pathologic bone loss.

J Bone Miner Res 2012 Dec;27(12):2442-51

Department of Internal Medicine 3, University of Erlangen-Nuremberg, Erlangen, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jbmr.1702DOI Listing
December 2012

Selective glucocorticoid receptor modulation maintains bone mineral density in mice.

J Bone Miner Res 2012 Nov;27(11):2242-50

Division of Endocrinology and Metabolic Bone Diseases, Department of Medicine III, Technical University, Dresden, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1002/jbmr.1688DOI Listing
November 2012

Glucocorticoid receptor dimerization induces MKP1 to protect against TNF-induced inflammation.

J Clin Invest 2012 Jun 15;122(6):2130-40. Epub 2012 May 15.

Department for Molecular Biomedical Research, VIB, Ghent, Belgium.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1172/JCI60006DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366401PMC
June 2012

A cell-autonomous role for the glucocorticoid receptor in skeletal muscle atrophy induced by systemic glucocorticoid exposure.

Am J Physiol Endocrinol Metab 2012 May 21;302(10):E1210-20. Epub 2012 Feb 21.

Dept. of Neurobiology, Physiology, and Behavior, Univ. of California, One Shields Ave., Davis, CA 95616-8519, USA.

View Article

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3361985PMC
http://dx.doi.org/10.1152/ajpendo.00512.2011DOI Listing
May 2012

Glucocorticoids enhance intestinal glucose uptake via the dimerized glucocorticoid receptor in enterocytes.

Endocrinology 2012 Apr 31;153(4):1783-94. Epub 2012 Jan 31.

Department of Cellular and Molecular Immunology, University of Göttingen Medical School, Göttingen 37073, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/en.2011-1747DOI Listing
April 2012

Glucocorticoid therapy of antigen-induced arthritis depends on the dimerized glucocorticoid receptor in T cells.

Proc Natl Acad Sci U S A 2011 Nov 14;108(48):19317-22. Epub 2011 Nov 14.

Tissue Specific Hormone Action, Leibniz Institute for Age Research-Fritz Lipmann Institute, 07745 Jena, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1073/pnas.1105857108DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228447PMC
November 2011

Liposomal encapsulation of glucocorticoids alters their mode of action in the treatment of experimental autoimmune encephalomyelitis.

J Immunol 2011 Oct 14;187(8):4310-8. Epub 2011 Sep 14.

Department of Neuroimmunology, Institute for Multiple Sclerosis Research and the Hertie Foundation, University of Göttingen Medical School, 37073 Göttingen, Germany.

View Article

Download full-text PDF

Source
http://www.jimmunol.org/lookup/doi/10.4049/jimmunol.1101604
Publisher Site
http://dx.doi.org/10.4049/jimmunol.1101604DOI Listing
October 2011

Retinoids stimulate periosteal bone resorption by enhancing the protein RANKL, a response inhibited by monomeric glucocorticoid receptor.

J Biol Chem 2011 Sep 29;286(36):31425-36. Epub 2011 Jun 29.

Department of Physiology and Biophysics, University of Arkansas for Medical Sciences, Little Rock, Arkansas 72205, USA.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1074/jbc.M111.247734DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3173101PMC
September 2011

Dissociation of osteogenic and immunological effects by the selective glucocorticoid receptor agonist, compound A, in human bone marrow stromal cells.

Endocrinology 2011 Jan 17;152(1):103-12. Epub 2010 Nov 17.

Division of Endocrinology, Diabetes, and Metabolic Bone Diseases, Department of Medicine III, Dresden Technical University Medical Center, Fetscherstrasse 74, 01307 Dresden, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/en.2010-0456DOI Listing
January 2011

Synergistic activation by p38MAPK and glucocorticoid signaling mediates induction of M2-like tumor-associated macrophages expressing the novel CD20 homolog MS4A8A.

Int J Cancer 2011 Jul 28;129(1):122-32. Epub 2010 Nov 28.

Department of Dermatology, Venereology and Allergology, University Medical Center and Medical Faculty Mannheim, University of Heidelberg, and Center of Excellence in Dermatology, Mannheim, Germany.

View Article

Download full-text PDF

Source
http://doi.wiley.com/10.1002/ijc.25657
Publisher Site
http://dx.doi.org/10.1002/ijc.25657DOI Listing
July 2011

Thymus-derived glucocorticoids mediate androgen effects on thymocyte homeostasis.

FASEB J 2010 Dec 26;24(12):5043-51. Epub 2010 Aug 26.

Department of Bioscience and Nutrition, Karolinska Institutet, SE-141 83 Huddinge, Stockholm, Sweden.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1096/fj.10-168724DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2992366PMC
December 2010

Prednisolone-induced differential gene expression in mouse liver carrying wild type or a dimerization-defective glucocorticoid receptor.

BMC Genomics 2010 Jun 5;11:359. Epub 2010 Jun 5.

Computational Drug Discovery (CDD), Nijmegen Centre for Molecular Life Sciences (NCMLS), Radboud University Nijmegen Medical Centre, Geert Grooteplein Zuid 26-28, Nijmegen, the Netherlands.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1186/1471-2164-11-359DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2895630PMC
June 2010

Meeting report: nuclear receptors: transcription factors and drug targets connecting basic research with translational medicine.

Mol Endocrinol 2010 Jul 2;24(7):1311-21. Epub 2010 Jun 2.

Leibniz Institute for Age Research-Fritz Lipmann Institute, D-07745 Jena, Germany.

View Article

Download full-text PDF

Source
http://dx.doi.org/10.1210/me.2010-0083DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5417462PMC
July 2010