Jan Stary

Jan Stary

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Jan Stary

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Hematopoietic stem cell transplantation for non-malignant hematological disorders.

Vnitr Lek Summer 2018;64(5):530-536

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May 2019

Sideroblastic anemia associated with multisystem mitochondrial disorders.

Pediatr Blood Cancer 2019 Apr 26;66(4):e27591. Epub 2018 Dec 26.

Department of Paediatrics and Adolescent Medicine, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic.

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http://doi.wiley.com/10.1002/pbc.27591
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http://dx.doi.org/10.1002/pbc.27591DOI Listing
April 2019

Increased proportions of γδ T lymphocytes in atypical SCID associate with disease manifestations.

Clin Immunol 2019 Apr 15;201:30-34. Epub 2019 Feb 15.

Center for Chronic Immunodeficiency, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany; Center for Pediatrics and Adolescent Medicine, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2018.11.006DOI Listing
April 2019

New biological and genetic classification and therapeutically relevant categories in childhood B-cell precursor acute lymphoblastic leukemia.

F1000Res 2018 28;7. Epub 2018 Sep 28.

Department of Pediatric Hematology and Oncology, Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic.

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https://f1000research.com/articles/7-1569/v1
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http://dx.doi.org/10.12688/f1000research.16074.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173109PMC
March 2019

Two novel fusion genes, AIF1L-ETV6 and ABL1-AIF1L, result together with ETV6-ABL1 from a single chromosomal rearrangement in acute lymphoblastic leukemia with prenatal origin.

Genes Chromosomes Cancer 2018 09 30;57(9):471-477. Epub 2018 Jul 30.

CLIP - Childhood Leukaemia Investigation Prague, Prague, Czech Republic.

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http://dx.doi.org/10.1002/gcc.6DOI Listing
September 2018

Appearance of cytomegalovirus-specific T-cells predicts fast resolution of viremia post hematopoietic stem cell transplantation.

Cytometry B Clin Cytom 2017 09 12;92(5):380-388. Epub 2016 Jan 12.

Department of Pediatric Hematology and Oncology, 2nd Faculty of Medicine, Charles University Prague and University Hospital Motol, V Uvalu 84, Prague, 150 06, Czech Republic.

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http://dx.doi.org/10.1002/cyto.b.21348DOI Listing
September 2017

Intragenic ERG Deletions Do Not Explain the Biology of ERG-Related Acute Lymphoblastic Leukemia.

PLoS One 2016 5;11(8):e0160385. Epub 2016 Aug 5.

Childhood Leukaemia Investigation Prague (CLIP), Department of Paediatric Haematology and Oncology, 2nd Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0160385PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975502PMC
July 2017

Lymphocyte enrichment using CD81-targeted immunoaffinity matrix.

Cytometry A 2017 01 4;91(1):62-72. Epub 2016 Aug 4.

CLIP - Childhood Leukemia Investigation Prague, Department of Pediatric Hematology and Oncology, 2nd Faculty of Medicine, Charles University Prague and University Hospital Motol, Prague, Czech Republic.

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http://dx.doi.org/10.1002/cyto.a.22918DOI Listing
January 2017

Recent advances in the management of pediatric acute lymphoblastic leukemia.

F1000Res 2016 4;5:2635. Epub 2016 Nov 4.

Department of Pediatric Hematology and Oncology, 2nd Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic.

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http://dx.doi.org/10.12688/f1000research.9548.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642309PMC
November 2016

Slower early response to treatment and distinct expression profile of childhood high hyperdiploid acute lymphoblastic leukaemia with DNA index < 1.16.

Genes Chromosomes Cancer 2016 09 23;55(9):727-37. Epub 2016 Jun 23.

CLIP,  Childhood Leukaemia Investigation Prague, Departmentof Paediatric Haematology and Oncology, 2nd Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic.

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http://dx.doi.org/10.1002/gcc.22374DOI Listing
September 2016

Loss of B cells and their precursors is the most constant feature of GATA-2 deficiency in childhood myelodysplastic syndrome.

Haematologica 2016 06 24;101(6):707-16. Epub 2016 Mar 24.

CLIP-Department of Pediatric Hematology and Oncology, 2 Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic Department of Pediatric Hematology and Oncology, 2 Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic

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http://dx.doi.org/10.3324/haematol.2015.137711DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013954PMC
June 2016

Exchange Transfusion and Leukapheresis in Pediatric Patients with AML With High Risk of Early Death by Bleeding and Leukostasis.

Pediatr Blood Cancer 2016 Apr 16;63(4):640-5. Epub 2015 Dec 16.

Department of Pediatric Hematology-Oncology, University of Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1002/pbc.25855DOI Listing
April 2016

Fanconi anemia with biallelic FANCD1/BRCA2 mutations - Case report of a family with three affected children.

Eur J Med Genet 2016 Mar 2;59(3):152-7. Epub 2015 Dec 2.

Department of Pediatric Hematology and Oncology, Charles University in Prague, Second Faculty of Medicine and University Hospital Motol, Prague, Czech Republic.

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http://dx.doi.org/10.1016/j.ejmg.2015.11.013DOI Listing
March 2016

Reprogramming of B cell acute lymphoblastic leukemia cells: Do we need to shoot a moving target?

Proc Natl Acad Sci U S A 2015 Jul 11;112(27):E3455. Epub 2015 Jun 11.

Childhood Leukemia Investigation Prague (CLIP), Second Faculty of Medicine, Charles University Prague and University Hospital Motol, 150 06 Prague, Czech Republic;

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http://dx.doi.org/10.1073/pnas.1508680112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500239PMC
July 2015

An unusual case of high hyperdiploid childhood ALL with cryptic BCR/ABL1 rearrangement.

Mol Cytogenet 2014 24;7(1):72. Epub 2014 Oct 24.

Center of Oncocytogenetics, Institute of Medical Biochemistry and Laboratory Diagnostics, General University Hospital in Prague and First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic.

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http://dx.doi.org/10.1186/s13039-014-0072-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213530PMC
October 2014

Combination of prednisolone and low dosed dexamethasone exhibits greater in vitro antileukemic activity than equiactive dose of prednisolone and overcomes prednisolone drug resistance in acute childhood lymphoblastic leukemia.

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2014 Sep 31;158(3):422-7. Epub 2012 Oct 31.

Laboratory of Experimental Medicine, Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University Olomouc and University Hospital Olomouc, Czech Republic.

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http://dx.doi.org/10.5507/bp.2012.059DOI Listing
September 2014

Molecular biology of testicular germ cell tumors: unique features awaiting clinical application.

Crit Rev Oncol Hematol 2014 Mar 11;89(3):366-85. Epub 2013 Oct 11.

Department of Pediatric Hematology and Oncology, 2nd Faculty of Medicine, Charles University and University Hospital in Motol, Prague, Czech Republic.

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http://dx.doi.org/10.1016/j.critrevonc.2013.10.001DOI Listing
March 2014

Cytokines, growth, and environment factors in bone marrow plasma of acute lymphoblastic leukemia pediatric patients.

Eur Cytokine Netw 2014 Mar;25(1):8-13

CLIP - Childhood Leukemia Investigation Prague, Department of Pediatric Hematology and Oncology, 2nd Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic.

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http://link.springer.com/content/pdf/10.1684%2Fecn.2014.0348
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http://www.john-libbey-eurotext.fr/medline.md?doi=10.1684/ec
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http://dx.doi.org/10.1684/ecn.2014.0348DOI Listing
March 2014

Intensive chemotherapy for childhood acute lymphoblastic leukemia: results of the randomized intercontinental trial ALL IC-BFM 2002.

J Clin Oncol 2014 Jan 16;32(3):174-84. Epub 2013 Dec 16.

Jan Stary, Jan Trka, and Ondrej Hrusak, Charles University and University Hospital Motol, Prague; Yahia Jabali, Regional Hospital, Ceske Budejovice, Czech Republic; Martin Zimmermann and Hansjörg Riehm, Medical School Hannover, Hannover; Martin Schrappe, University Hospital Schleswig-Holstein, Kiel, Germany; Myriam Campbell, Roberto del Rio Hospital, Universidad de Chile, Santiago, Chile; Luis Castillo, Hospital Pereira Rossell, Montevideo, Uruguay; Eduardo Dibar, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Svetlana Donska, Regional Oncologic Hospital, Kiev, Ukraine; Alejandro Gonzalez, Institute of Hematology and Immunology, La Habana, Cuba; Shai Izraeli, Sheba Medical Center of Israel, Sackler School of Medicine, Tel Aviv University, Tel Hashomer; Batia Stark, Schneider Children's Medical Center of Israel, Sackler School of Medicine, Tel Aviv University, Petah-Tikva, Israel; Dragana Janic, University Children's Hospital, University of Belgrade, Belgrade, Serbia; Janez Jazbec, University Children's Hospital, Ljubljana, Slovenia; Josip Konja, University Hospital Centre Rebro, Zagreb, Croatia; Emilia Kaiserova, University Children's Hospital, Bratislava, Slovakia; Jerzy Kowalczyk, University of Lublin, Lublin, Poland; Gabor Kovacs and Edina Magyarosy, Semmelweis University, Budapest, Hungary; Chi-Kong Li, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong, Special Administrative Region, People's Republic of China; Alexander Popa, N.N. Blokhin Russian Cancer Research Center, Moscow, Russia; and Giuseppe Masera, Ospedale S. Gerardo, University of Milano-Bicocca, Monza, Italy.

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http://dx.doi.org/10.1200/JCO.2013.48.6522DOI Listing
January 2014

Ikaros (IKZF1) alterations and minimal residual disease at day 15 assessed by flow cytometry predict prognosis of childhood BCR/ABL-negative acute lymphoblastic leukemia.

Pediatr Blood Cancer 2013 Mar 19;60(3):420-7. Epub 2012 Sep 19.

2nd Faculty of Medicine, Department of Pediatric Hematology and Oncology, Charles University and University Hospital Motol, Prague, Czech Republic.

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http://dx.doi.org/10.1002/pbc.24299DOI Listing
March 2013

Optimizing asparaginase therapy for acute lymphoblastic leukemia.

Curr Opin Oncol 2013 Mar;25 Suppl 1:S1-9

Department of Pediatrics, San Gerardo Hospital, University of Milano-Bicocca, Monza, Italy.

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http://dx.doi.org/10.1097/CCO.0b013e32835d7d85DOI Listing
March 2013

CBL mutations do not frequently occur in paediatric acute myeloid leukaemia.

Br J Haematol 2012 Dec 1;159(5):577-84. Epub 2012 Oct 1.

Department of Paediatric Oncology/Haematology, Erasmus MC/Sophia Children's Hospital, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1111/bjh.12068DOI Listing
December 2012

Valproic acid triggers differentiation and apoptosis in AML1/ETO-positive leukemic cells specifically.

Cancer Lett 2012 Jun 17;319(2):144-153. Epub 2012 Jan 17.

CLIP, Department of Pediatric Hematology and Oncology, Charles University, 2nd Medical School, Prague, Czech Republic.

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http://dx.doi.org/10.1016/j.canlet.2011.12.041DOI Listing
June 2012

Skin lesions in a boy with X-linked lymphoproliferative disorder: comparison of 5 SH2D1A deletion cases.

Pediatrics 2012 Feb 23;129(2):e523-8. Epub 2012 Jan 23.

Department of Pediatric Hematology and Oncology, Charles University 2nd Faculty of Medicine and University Hospital Motol, Prague, Czech Republic.

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http://dx.doi.org/10.1542/peds.2011-0870DOI Listing
February 2012

TEL/AML1-positive patients lacking TEL exon 5 resemble canonical TEL/AML1 cases.

Pediatr Blood Cancer 2011 Feb 22;56(2):217-25. Epub 2010 Oct 22.

CLIP, Department of Pediatric Hematology and Oncology, 2nd Faculty of Medicine, Charles University Prague and University Hospital Motol, Prague, Czech Republic.

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http://dx.doi.org/10.1002/pbc.22686DOI Listing
February 2011

Acute leukemias with ETV6/ABL1 (TEL/ABL) fusion: poor prognosis and prenatal origin.

Genes Chromosomes Cancer 2010 Oct;49(10):873-84

Department of Pediatric Hematology and Oncology, CLIP (Childhood Leukaemia Investigation Prague), Charles University Prague, 2nd Faculty of Medicine and University Hospital Motol, Prague, Czech Republic.

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http://dx.doi.org/10.1002/gcc.20796DOI Listing
October 2010

A novel recurrent chromosomal aberration involving chromosome 7 in childhood myelodysplastic syndrome.

Cancer Genet Cytogenet 2010 Aug;201(1):52-6

Center of Oncocytogenetics, Institute of Clinical Biochemistry and Laboratory Diagnostics, General University Hospital and 1st Faculty of Medicine, Charles University in Prague, U Nemocnice 2, Prague, Czech Republic.

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http://dx.doi.org/10.1016/j.cancergencyto.2010.05.004DOI Listing
August 2010

Favourable outcome of patients with childhood acute promyelocytic leukaemia after treatment with reduced cumulative anthracycline doses.

Br J Haematol 2010 May 8;149(3):399-409. Epub 2010 Mar 8.

University Children's Hospital, Department of Paediatric Haematology/Oncology, Muenster, Hannover, Germany.

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http://dx.doi.org/10.1111/j.1365-2141.2010.08107.xDOI Listing
May 2010

Salvage treatment for children with refractory first or second relapse of acute myeloid leukaemia with gemtuzumab ozogamicin: results of a phase II study.

Br J Haematol 2010 Mar 8;148(5):768-76. Epub 2009 Dec 8.

Department of Paediatric Oncology/Haematology, Sophia Children's Hospital, Erasmus Medical Centre, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1111/j.1365-2141.2009.08011.xDOI Listing
March 2010

Bone marrow transplantation for inherited bone marrow failure syndromes.

Pediatr Clin North Am 2010 Feb;57(1):147-70

Cincinnati Children's Hospital Medical Center and the University of Cincinnati College of Medicine, 3333 Burnet Avenue, Cincinnati, OH 45229, USA.

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http://dx.doi.org/10.1016/j.pcl.2010.01.002DOI Listing
February 2010

Cytogenetic and array comparative genomic hybridization analysis of a series of hepatoblastomas.

Cancer Genet Cytogenet 2009 Oct;194(2):82-7

Department of Pediatric Hematology and Oncology, Oncocytogenetics, University Hospital-Motol, V Uvalu 84, 15006 Prague 5, Czech Republic.

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http://dx.doi.org/10.1016/j.cancergencyto.2009.06.001DOI Listing
October 2009