Jan Stary

Jan Stary

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Jan Stary

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Long-term treatment results of Polish pediatric and adolescent patients enrolled in the ALL IC-BFM 2002 trial.

Authors:
Jerzy R Kowalczyk Joanna Zawitkowska Monika Lejman Katarzyna Drabko Marzena Samardakiewicz Michał Matysiak Michał Romiszewski Walentyna Balwierz Magdalena Ćwiklińska Bernarda Kazanowska Joanna Owoc-Lempach Jacek Wachowiak Katarzyna Derwich Elżbieta Adamkiewicz-Drożyńska Maciej Niedźwiecki Joanna Trelińska Wojciech Młynarski Mariusz Wysocki Andrzej Kołtan Tomasz Szczepański Maryna Krawczuk-Rybak Anna Kitszel Maria Wieczorek Tomasz Urasiński Tomasz Ociepa Grażyna Sobol-Milejska Agnieszka Mizia-Malarz Grażyna Karolczyk Jan Stary

Am J Hematol 2019 Nov 30;94(11):E307-E310. Epub 2019 Aug 30.

Department of Pediatric Hematology and Oncology, Charles University and University Hospital Motol, Prague, Czech Republic.

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http://dx.doi.org/10.1002/ajh.25619DOI Listing
November 2019

Phase I dose-escalation study of volasertib in pediatric patients with acute leukemia or advanced solid tumors.

Authors:
François Doz Franco Locatelli André Baruchel Nicolas Blin Barbara De Moerloose Didier Frappaz Michael Dworzak Matthias Fischer Jan Stary Rene Fuertig Kathrin Riemann Tillmann Taube Dirk Reinhardt

Pediatr Blood Cancer 2019 Oct 5;66(10):e27900. Epub 2019 Jul 5.

Department of Paediatrics, University Hospital Essen, Essen, Germany.

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http://dx.doi.org/10.1002/pbc.27900DOI Listing
October 2019

Asparagine levels in the cerebrospinal fluid of children with acute lymphoblastic leukemia treated with pegylated-asparaginase in the induction phase of the AIEOP-BFM ALL 2009 study.

Authors:
Carmelo Rizzari Claudia Lanvers-Kaminsky Maria Grazia Valsecchi Andrea Ballerini Cristina Matteo Joachim Gerss Gudrun Wuerthwein Daniela Silvestri Antonella Colombini Valentino Conter Andrea Biondi Martin Schrappe Anja Moericke Martin Zimmermann Arend von Stackelberg Christin Linderkamp Michael C Frühwald Sabine Legien Andishe Attarbaschi Bettina Reismüller David Kasper Petr Smisek Jan Stary Luciana Vinti Elena Barisone Rosanna Parasole Concetta Micalizzi Massimo Zucchetti Joachim Boos

Haematologica 2019 Sep 31;104(9):1812-1821. Epub 2019 Jan 31.

Department of Pediatric Hematology and Oncology, University Childrens' Hospital of Münster, Münster, Germany.

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http://dx.doi.org/10.3324/haematol.2018.206433DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6717578PMC
September 2019

Outcome of Infants Younger Than 1 Year With Acute Lymphoblastic Leukemia Treated With the Interfant-06 Protocol: Results From an International Phase III Randomized Study.

Authors:
Rob Pieters Paola De Lorenzo Philip Ancliffe Luis Alberto Aversa Benoit Brethon Andrea Biondi Myriam Campbell Gabriele Escherich Alina Ferster Rebecca A Gardner Rishi Sury Kotecha Birgitte Lausen Chi Kong Li Franco Locatelli Andishe Attarbaschi Christina Peters Jeffrey E Rubnitz Lewis B Silverman Jan Stary Tomasz Szczepanski Ajay Vora Martin Schrappe Maria Grazia Valsecchi

J Clin Oncol 2019 Sep 8;37(25):2246-2256. Epub 2019 Jul 8.

University of Milano-Bicocca, Monza, Italy.

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http://dx.doi.org/10.1200/JCO.19.00261DOI Listing
September 2019

Novel SAMD9 Mutation in a Patient With Immunodeficiency, Neutropenia, Impaired Anti-CMV Response, and Severe Gastrointestinal Involvement.

Authors:
Renata Formankova Veronika Kanderova Marketa Rackova Michael Svaton Tomas Brdicka Petr Riha Petra Keslova Ester Mejstrikova Marketa Zaliova Tomas Freiberger Hana Grombirikova Zuzana Zemanova Marcela Vlkova Filip Fencl Ivana Copova Jiri Bronsky Petr Jabandziev Petr Sedlacek Jana Soukalova Ondrej Zapletal Jan Stary Jan Trka Tomas Kalina Karolina Skvarova Kramarzova Eva Hlavackova Jiri Litzman Eva Fronkova

Front Immunol 2019 18;10:2194. Epub 2019 Sep 18.

Department of Paediatric Haematology and Oncology, 2nd Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czechia.

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http://dx.doi.org/10.3389/fimmu.2019.02194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6759462PMC
September 2019

deletions in childhood acute lymphoblastic leukemia with rearrangements are mostly polyclonal, prognostically relevant and their detection rate strongly depends on screening method sensitivity.

Authors:
Marketa Zaliova Eliska Potuckova Lenka Hovorkova Alena Musilova Lucie Winkowska Karel Fiser Jan Stuchly Ester Mejstrikova Julia Starkova Jan Zuna Jan Stary Jan Trka

Haematologica 2019 Jul 10;104(7):1407-1416. Epub 2019 Jan 10.

CLIP - Childhood Leukaemia Investigation Prague.

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http://dx.doi.org/10.3324/haematol.2018.204487DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601096PMC
July 2019

Genomic landscape of pediatric B-other acute lymphoblastic leukemia in a consecutive European cohort.

Authors:
Marketa Zaliova Jan Stuchly Lucie Winkowska Alena Musilova Karel Fiser Martina Slamova Julia Starkova Martina Vaskova Ondrej Hrusak Lucie Sramkova Jan Stary Jan Zuna Jan Trka

Haematologica 2019 Jul 10;104(7):1396-1406. Epub 2019 Jan 10.

CLIP - Childhood Leukaemia Investigation Prague

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http://www.haematologica.org/lookup/doi/10.3324/haematol.201
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http://dx.doi.org/10.3324/haematol.2018.204974DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6601078PMC
July 2019

Hematopoietic stem cell transplantation for non-malignant hematological disorders.

Authors:
Renata Formánková Jan Starý

Vnitr Lek Summer 2018;64(5):530-536

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May 2019

Cytometric analysis of cell suspension generated by cavitron ultrasonic surgical aspirator in pediatric brain tumors.

Authors:
Martina Vaskova Michal Tichy Josef Zamecnik Petr Liby Daniela Kuzilkova Ales Vicha Jan Hrabeta Tomas Kalina Jan Stary Ondrej Hrusak

J Neurooncol 2019 May 2;143(1):15-25. Epub 2019 Mar 2.

CLIP - Childhood Leukaemia Investigation Prague, Prague, Czech Republic.

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http://link.springer.com/10.1007/s11060-019-03135-w
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http://dx.doi.org/10.1007/s11060-019-03135-wDOI Listing
May 2019

Sideroblastic anemia associated with multisystem mitochondrial disorders.

Authors:
Marketa Tesarova Alzbeta Vondrackova Hana Stufkova Lenka Veprekova Viktor Stranecky Kamila Berankova Hana Hansikova Martin Magner Natalia Galoova Tomas Honzik Elena Vodickova Jan Stary Jiri Zeman

Pediatr Blood Cancer 2019 Apr 26;66(4):e27591. Epub 2018 Dec 26.

Department of Paediatrics and Adolescent Medicine, First Faculty of Medicine, Charles University and General University Hospital, Prague, Czech Republic.

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http://doi.wiley.com/10.1002/pbc.27591
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http://dx.doi.org/10.1002/pbc.27591DOI Listing
April 2019

Outcome of Children With Hypodiploid Acute Lymphoblastic Leukemia: A Retrospective Multinational Study.

Authors:
Ching-Hon Pui Paola Rebora Martin Schrappe Andishe Attarbaschi Andre Baruchel Giuseppe Basso Hélène Cavé Sarah Elitzur Katsuyoshi Koh Hsi-Che Liu Kajsa Paulsson Rob Pieters Lewis B Silverman Jan Stary Ajay Vora Allen Yeoh Christine J Harrison Maria Grazia Valsecchi

J Clin Oncol 2019 Apr 18;37(10):770-779. Epub 2019 Jan 18.

2 University of Milano-Bicocca, Monza, Italy.

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http://ascopubs.org/doi/10.1200/JCO.18.00822
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http://dx.doi.org/10.1200/JCO.18.00822DOI Listing
April 2019

Increased proportions of γδ T lymphocytes in atypical SCID associate with disease manifestations.

Authors:
Inga Tometten Kerstin Felgentreff Manfred Hönig Fabian Hauck Michael H Albert Tim Niehues Ruy Perez Sujal Ghosh Capucine Picard Jan Stary Renata Formankova Austen Worth Pere Soler-Palacín Marina García-Prat Luis M Allende Luis Ignacio Gonzalez-Granado Polina Stepensky Silvia Di Cesare Alessia Scarselli Caterina Cancrini Carsten Speckmann Kimberly Gilmour Luigi Notarangelo Stephan Ehl Jan C Rohr

Clin Immunol 2019 Apr 15;201:30-34. Epub 2019 Feb 15.

Center for Chronic Immunodeficiency, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany; Center for Pediatrics and Adolescent Medicine, Medical Center, Faculty of Medicine, University of Freiburg, Freiburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2018.11.006DOI Listing
April 2019

New biological and genetic classification and therapeutically relevant categories in childhood B-cell precursor acute lymphoblastic leukemia.

Authors:
Jan Starý Jan Zuna Marketa Zaliova

F1000Res 2018 28;7. Epub 2018 Sep 28.

Department of Pediatric Hematology and Oncology, Second Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic.

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https://f1000research.com/articles/7-1569/v1
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http://dx.doi.org/10.12688/f1000research.16074.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6173109PMC
March 2019

Long-term follow up of pediatric Philadelphia positive acute lymphoblastic leukemia treated with the EsPhALL2004 study: high white blood cell count at diagnosis is the strongest prognostic factor.

Authors:
Andrea Biondi Gunnar Cario Paola De Lorenzo Anders Castor Valentino Conter Veronica Leoni Virginie Gandemer Rob Pieters Jan Stary Gabriele Escherich Myriam Campbell Andishe Attarbaschi Chi-Kong Li Ajay Vora Jutta Bradtke Vaskar Saha Maria Grazia Valsecchi Martin Schrappe

Haematologica 2019 Jan 13;104(1):e13-e16. Epub 2018 Sep 13.

University Medical Center, Christian-Albrechts-University Kiel, Germany.

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http://www.haematologica.org/lookup/doi/10.3324/haematol.201
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http://dx.doi.org/10.3324/haematol.2018.199422DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6312020PMC
January 2019

Validation of the United Kingdom copy-number alteration classifier in 3239 children with B-cell precursor ALL.

Authors:
Lina Hamadeh Amir Enshaei Claire Schwab Cristina N Alonso Andishe Attarbaschi Gisela Barbany Monique L den Boer Judith M Boer Marcin Braun Luciano Dalla Pozza Sarah Elitzur Mariana Emerenciano Larisa Fechina Maria Sara Felice Eva Fronkova Irén Haltrich Mats M Heyman Keizo Horibe Toshihiko Imamura Marta Jeison Gábor Kovács Roland P Kuiper Wojciech Mlynarski Karin Nebral Ingegerd Ivanov Öfverholm Agata Pastorczak Rob Pieters Henriett Piko Maria S Pombo-de-Oliveira Patricia Rubio Sabine Strehl Jan Stary Rosemary Sutton Jan Trka Grigory Tsaur Nicola Venn Ajay Vora Mio Yano Christine J Harrison Anthony V Moorman

Blood Adv 2019 01;3(2):148-157

Wolfson Childhood Cancer Research Centre, Northern Institute for Cancer Research, Newcastle University, Newcastle, United Kingdom.

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http://dx.doi.org/10.1182/bloodadvances.2018025718DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341196PMC
January 2019

Imatinib treatment of paediatric Philadelphia chromosome-positive acute lymphoblastic leukaemia (EsPhALL2010): a prospective, intergroup, open-label, single-arm clinical trial.

Authors:
Andrea Biondi Virginie Gandemer Paola De Lorenzo Gunnar Cario Myriam Campbell Anders Castor Rob Pieters André Baruchel Ajay Vora Veronica Leoni Jan Stary Gabriele Escherich Chi-Kong Li Giovanni Cazzaniga Hélène Cavé Jutta Bradtke Valentino Conter Vaskar Saha Martin Schrappe Maria Grazia Valsecchi

Lancet Haematol 2018 Dec;5(12):e641-e652

EsPhALL Trial Data Center, School of Medicine and Surgery, University of Milano-Bicocca, Fondazione MBBM, Monza, Italy.

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https://linkinghub.elsevier.com/retrieve/pii/S23523026183017
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http://dx.doi.org/10.1016/S2352-3026(18)30173-XDOI Listing
December 2018

The long non-coding RNA landscape in juvenile myelomonocytic leukemia.

Authors:
Mattias Hofmans Tim Lammens Hetty H Helsmoortel Silvia Bresolin Hélène Cavé Christian Flotho Henrik Hasle Marry M van den Heuvel-Eibrink Charlotte Niemeyer Jan Stary Nadine Van Roy Pieter Van Vlierberghe Jan Philippé Barbara De Moerloose

Haematologica 2018 11 1;103(11):e501-e504. Epub 2018 Jun 1.

Department of Pediatric Hematology-Oncology and Stem Cell Transplantation, Ghent University Hospital, Belgium.

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http://dx.doi.org/10.3324/haematol.2018.189977DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6278979PMC
November 2018

Treatment dilemmas in asymptomatic children with primary hemophagocytic lymphohistiocytosis.

Authors:
Giovanna Lucchini Rebecca Marsh Kimberly Gilmour Austen Worth Zohreh Nademi Anupama Rao Claire Booth Persis Amrolia Juliana Silva Robert Chiesa Robert Wynn Kai Lehmberg Itziar Astigarraga Tayfun Güngör Jan Stary Despina Moshous Marianne Ifversen Daniel Zinn Michael Jordan Ashish Kumar Takahiro Yasumi Paul Veys Kanchan Rao

Blood 2018 11 13;132(19):2088-2096. Epub 2018 Aug 13.

Department of Immunology/Stem Cell Transplant, Great Ormond Street Hospital, London, United Kingdom.

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http://dx.doi.org/10.1182/blood-2018-01-827485DOI Listing
November 2018

Prognostic impact of t(16;21)(p11;q22) and t(16;21)(q24;q22) in pediatric AML: a retrospective study by the I-BFM Study Group.

Authors:
Sanne Noort Martin Zimmermann Dirk Reinhardt Wendy Cuccuini Martina Pigazzi Jenny Smith Rhonda E Ries Todd A Alonzo Betsy Hirsch Daisuke Tomizawa Franco Locatelli Tanja A Gruber Susana Raimondi Edwin Sonneveld Daniel K Cheuk Michael Dworzak Jan Stary Jonas Abrahamsson Nira Arad-Cohen Malgorzata Czogala Barbara De Moerloose Henrik Hasle Soheil Meshinchi Marry van den Heuvel-Eibrink C Michel Zwaan

Blood 2018 10 27;132(15):1584-1592. Epub 2018 Aug 27.

Pediatric Oncology/Hematology, Erasmus MC-Sophia Children's Hospital Rotterdam, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1182/blood-2018-05-849059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6265640PMC
October 2018

Two novel fusion genes, AIF1L-ETV6 and ABL1-AIF1L, result together with ETV6-ABL1 from a single chromosomal rearrangement in acute lymphoblastic leukemia with prenatal origin.

Authors:
Julius Lukes Eliska Potuckova Lucie Sramkova Jan Stary Julia Starkova Jan Trka Felix Votava Jan Zuna Marketa Zaliova

Genes Chromosomes Cancer 2018 09 30;57(9):471-477. Epub 2018 Jul 30.

CLIP - Childhood Leukaemia Investigation Prague, Prague, Czech Republic.

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http://dx.doi.org/10.1002/gcc.6DOI Listing
September 2018

Clofarabine, high-dose cytarabine and liposomal daunorubicin in pediatric relapsed/refractory acute myeloid leukemia: a phase IB study.

Authors:
Natasha K A van Eijkelenburg Mareike Rasche Essam Ghazaly Michael N Dworzak Thomas Klingebiel Claudia Rossig Guy Leverger Jan Stary Eveline S J M De Bont Dana A Chitu Yves Bertrand Benoit Brethon Brigitte Strahm Inge M van der Sluis Gertjan J L Kaspers Dirk Reinhardt C Michel Zwaan

Haematologica 2018 09 17;103(9):1484-1492. Epub 2018 May 17.

Department of Pediatric Oncology/Hematology, Erasmus MC-Sophia Children's Hospital, Rotterdam, the Netherlands

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http://dx.doi.org/10.3324/haematol.2017.187153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6119144PMC
September 2018

International cooperative study identifies treatment strategy in childhood ambiguous lineage leukemia.

Authors:
Ondrej Hrusak Valerie de Haas Jitka Stancikova Barbora Vakrmanova Iveta Janotova Ester Mejstrikova Vaclav Capek Jan Trka Marketa Zaliova Ales Luks Kirsten Bleckmann Anja Möricke Julie Irving Benigna Konatkowska Thomas B Alexander Hiroto Inaba Kjeld Schmiegelow Simone Stokley Zuzana Zemanova Anthony V Moorman Jorge Gabriel Rossi Maria Sara Felice Luciano Dalla-Pozza Jessa Morales Michael Dworzak Barbara Buldini Giuseppe Basso Myriam Campbell Maria Elena Cabrera Neda Marinov Sarah Elitzur Shai Izraeli Drorit Luria Tamar Feuerstein Alexandra Kolenova Peter Svec Olena Kreminska Karen R Rabin Sophia Polychronopoulou Elaine da Costa Hanne Vibeke Marquart Antonis Kattamis Richard Ratei Dirk Reinhardt John K Choi Martin Schrappe Jan Stary

Blood 2018 07 2;132(3):264-276. Epub 2018 May 2.

Department of Pediatric Hematology/Oncology, Charles University, Second Faculty of Medicine, Hospital Motol, Prague, Czech Republic.

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http://dx.doi.org/10.1182/blood-2017-12-821363DOI Listing
July 2018

Differential patterns of metastatic dissemination across medulloblastoma subgroups.

Authors:
Michal Zapotocky Daddy Mata-Mbemba David Sumerauer Petr Liby Alvaro Lassaletta Josef Zamecnik Lenka Krskova Martin Kyncl Jan Stary Suzanne Laughlin Anthony Arnoldo Cynthia Hawkins Uri Tabori Michael D Taylor Eric Bouffet Charles Raybaud Vijay Ramaswamy

J Neurosurg Pediatr 2018 02 8;21(2):145-152. Epub 2017 Dec 8.

1Department of Paediatrics, Division of Haematology/Oncology.

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http://dx.doi.org/10.3171/2017.8.PEDS17264DOI Listing
February 2018

Predictive value of minimal residual disease in Philadelphia-chromosome-positive acute lymphoblastic leukemia treated with imatinib in the European intergroup study of post-induction treatment of Philadelphia-chromosome-positive acute lymphoblastic leukemia, based on immunoglobulin/T-cell receptor and BCR/ABL1 methodologies.

Authors:
Giovanni Cazzaniga Paola De Lorenzo Julia Alten Silja Röttgers Jeremy Hancock Vaskar Saha Anders Castor Hans O Madsen Virginie Gandemer Hélène Cavé Veronica Leoni Rolf Köhler Giulia M Ferrari Kirsten Bleckmann Rob Pieters Vincent van der Velden Jan Stary Jan Zuna Gabriele Escherich Udo Zur Stadt Maurizio Aricò Valentino Conter Martin Schrappe Maria Grazia Valsecchi Andrea Biondi

Haematologica 2018 01 27;103(1):107-115. Epub 2017 Oct 27.

Associazione Italiana Ematologia Oncologia Pediatrica (AIEOP), Centro Ricerca Tettamanti, Pediatric Department, University of Milano-Bicocca, Monza, Italy.

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http://dx.doi.org/10.3324/haematol.2017.176917DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5777198PMC
January 2018

RAS-pathway mutation patterns define epigenetic subclasses in juvenile myelomonocytic leukemia.

Authors:
Daniel B Lipka Tania Witte Reka Toth Jing Yang Manuel Wiesenfarth Peter Nöllke Alexandra Fischer David Brocks Zuguang Gu Jeongbin Park Brigitte Strahm Marcin Wlodarski Ayami Yoshimi Rainer Claus Michael Lübbert Hauke Busch Melanie Boerries Mark Hartmann Maximilian Schönung Umut Kilik Jens Langstein Justyna A Wierzbinska Caroline Pabst Swati Garg Albert Catalá Barbara De Moerloose Michael Dworzak Henrik Hasle Franco Locatelli Riccardo Masetti Markus Schmugge Owen Smith Jan Stary Marek Ussowicz Marry M van den Heuvel-Eibrink Yassen Assenov Matthias Schlesner Charlotte Niemeyer Christian Flotho Christoph Plass

Nat Commun 2017 12 19;8(1):2126. Epub 2017 Dec 19.

Cancer Epigenetics Group, Division of Epigenomics and Cancer Risk Factors, German Cancer Research Center (DKFZ), INF 280, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1038/s41467-017-02177-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5736667PMC
December 2017

Appearance of cytomegalovirus-specific T-cells predicts fast resolution of viremia post hematopoietic stem cell transplantation.

Authors:
Ondřej Pelák Jan Stuchlý Ladislav Król Petr Hubáček Petra Keslová Petr Sedláček Renata Formánková Jan Starý Ondřej Hrušák Tomáš Kalina

Cytometry B Clin Cytom 2017 09 12;92(5):380-388. Epub 2016 Jan 12.

Department of Pediatric Hematology and Oncology, 2nd Faculty of Medicine, Charles University Prague and University Hospital Motol, V Uvalu 84, Prague, 150 06, Czech Republic.

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http://dx.doi.org/10.1002/cyto.b.21348DOI Listing
September 2017

ETV6/RUNX1-like acute lymphoblastic leukemia: A novel B-cell precursor leukemia subtype associated with the CD27/CD44 immunophenotype.

Authors:
Marketa Zaliova Michaela Kotrova Silvia Bresolin Jan Stuchly Jan Stary Ondrej Hrusak Geertruy Te Kronnie Jan Trka Jan Zuna Martina Vaskova

Genes Chromosomes Cancer 2017 08 5;56(8):608-616. Epub 2017 May 5.

CLIP-Childhood Leukaemia Investigation Prague, Czech Republic.

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http://dx.doi.org/10.1002/gcc.22464DOI Listing
August 2017

Intragenic ERG Deletions Do Not Explain the Biology of ERG-Related Acute Lymphoblastic Leukemia.

Authors:
Eliska Potuckova Jan Zuna Lenka Hovorkova Julia Starkova Jan Stary Jan Trka Marketa Zaliova

PLoS One 2016 5;11(8):e0160385. Epub 2016 Aug 5.

Childhood Leukaemia Investigation Prague (CLIP), Department of Paediatric Haematology and Oncology, 2nd Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0160385PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4975502PMC
July 2017

Acute lymphoblastic leukemia with aleukemic prodrome: preleukemic dynamics and possible mechanisms of immunosurveillance.

Authors:
Olga Zimmermannova Marketa Zaliova Anthony V Moorman Halima Al-Shehhi Eva Fronkova Zuzana Zemanova Tomas Kalina Ajay Vora Jan Stary Jan Trka Ondrej Hrusak Jan Zuna

Haematologica 2017 06 2;102(6):e225-e228. Epub 2017 Mar 2.

CLIP, Childhood Leukaemia Investigation Prague, Czech Republic

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http://dx.doi.org/10.3324/haematol.2016.161380DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5451349PMC
June 2017

Monitoring of childhood ALL using genomic breakpoints identifies a subgroup with CML-like biology.

Authors:
Lenka Hovorkova Marketa Zaliova Nicola C Venn Kirsten Bleckmann Marie Trkova Eliska Potuckova Martina Vaskova Jana Linhartova Katerina Machova Polakova Eva Fronkova Walter Muskovic Jodie E Giles Peter J Shaw Gunnar Cario Rosemary Sutton Jan Stary Jan Trka Jan Zuna

Blood 2017 05 22;129(20):2771-2781. Epub 2017 Mar 22.

Childhood Leukemia Investigation Prague (CLIP) and.

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http://dx.doi.org/10.1182/blood-2016-11-749978DOI Listing
May 2017

Lymphocyte enrichment using CD81-targeted immunoaffinity matrix.

Authors:
Ondřej Pelák Daniela Kužílková Daniel Thürner Marie-Luise Kiene Kristian Stanar Jan Stuchlý Martina Vášková Jan Starý Ondřej Hrušák Herbert Stadler Tomáš Kalina

Cytometry A 2017 01 4;91(1):62-72. Epub 2016 Aug 4.

CLIP - Childhood Leukemia Investigation Prague, Department of Pediatric Hematology and Oncology, 2nd Faculty of Medicine, Charles University Prague and University Hospital Motol, Prague, Czech Republic.

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http://dx.doi.org/10.1002/cyto.a.22918DOI Listing
January 2017

Distinct bilineal leukemia immunophenotypes are not genetically determined.

Authors:
Michaela Kotrova Alena Musilova Jan Stuchly Karel Fiser Julia Starkova Ester Mejstrikova Jan Stary Jan Zuna Ondrej Hrusak Jan Trka Marketa Zaliova

Blood 2016 11 13;128(18):2263-2266. Epub 2016 Sep 13.

Childhood Leukaemia Investigation Prague, and.

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http://dx.doi.org/10.1182/blood-2016-07-725861DOI Listing
November 2016

Recent advances in the management of pediatric acute lymphoblastic leukemia.

Authors:
Jan Starý Ondřej Hrušák

F1000Res 2016 4;5:2635. Epub 2016 Nov 4.

Department of Pediatric Hematology and Oncology, 2nd Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic.

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http://dx.doi.org/10.12688/f1000research.9548.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642309PMC
November 2016

Slower early response to treatment and distinct expression profile of childhood high hyperdiploid acute lymphoblastic leukaemia with DNA index < 1.16.

Authors:
Marketa Zaliova Lenka Hovorkova Martina Vaskova Ondrej Hrusak Jan Stary Jan Zuna

Genes Chromosomes Cancer 2016 09 23;55(9):727-37. Epub 2016 Jun 23.

CLIP,  Childhood Leukaemia Investigation Prague, Departmentof Paediatric Haematology and Oncology, 2nd Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic.

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http://dx.doi.org/10.1002/gcc.22374DOI Listing
September 2016

Characterization of leukemias with ETV6-ABL1 fusion.

Authors:
Marketa Zaliova Anthony V Moorman Giovanni Cazzaniga Martin Stanulla Richard C Harvey Kathryn G Roberts Sue L Heatley Mignon L Loh Marina Konopleva I-Ming Chen Olga Zimmermannova Claire Schwab Owen Smith Marie-Joelle Mozziconacci Christian Chabannon Myungshin Kim J H Frederik Falkenburg Alice Norton Karen Marshall Oskar A Haas Julia Starkova Jan Stuchly Stephen P Hunger Deborah White Charles G Mullighan Cheryl L Willman Jan Stary Jan Trka Jan Zuna

Haematologica 2016 09 26;101(9):1082-93. Epub 2016 May 26.

CLIP, Department of Pediatric Hematology and Oncology, 2 Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic

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http://dx.doi.org/10.3324/haematol.2016.144345DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5060025PMC
September 2016

Implications of delayed bone marrow aspirations at the end of treatment induction for risk stratification and outcome in children with acute lymphoblastic leukaemia.

Authors:
Jan Zuna Anja Moericke Mari Arens Rolf Koehler Renate Panzer-Grümayer Claus R Bartram Susanna Fischer Eva Fronkova Marketa Zaliova André Schrauder Martin Stanulla Martin Zimmermann Jan Trka Jan Stary Andishe Attarbaschi Georg Mann Martin Schrappe Gunnar Cario

Br J Haematol 2016 06 23;173(5):742-8. Epub 2016 Feb 23.

Department of Paediatrics, University Medical Centre Schleswig-Holstein, Campus Kiel, Kiel, Germany.

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http://dx.doi.org/10.1111/bjh.13989DOI Listing
June 2016

LIN28B is over-expressed in specific subtypes of pediatric leukemia and regulates lncRNA H19.

Authors:
Hetty H Helsmoortel Barbara De Moerloose Tim Pieters Farzaneh Ghazavi Silvia Bresolin Hélène Cavé Andrica de Vries Valerie de Haas Christian Flotho Veerle Labarque Charlotte Niemeyer Pascale De Paepe Nadine Van Roy Jan Stary Marry M van den Heuvel-Eibrink Yves Benoit Johannes Schulte Steven Goossens Geert Berx Jody J Haigh Frank Speleman Pieter Van Vlierberghe Tim Lammens

Haematologica 2016 06 11;101(6):e240-4. Epub 2016 Mar 11.

Department of Paediatric Haematology-Oncology and Stem Cell Transplantation, Ghent University Hospital, Belgium

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http://dx.doi.org/10.3324/haematol.2016.143818DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013963PMC
June 2016

Loss of B cells and their precursors is the most constant feature of GATA-2 deficiency in childhood myelodysplastic syndrome.

Authors:
Michaela Nováková Markéta Žaliová Martina Suková Marcin Wlodarski Aleš Janda Eva Froňková Vít Campr Kateřina Lejhancová Ondřej Zapletal Dagmar Pospíšilová Zdeňka Černá Tomáš Kuhn Peter Švec Vendula Pelková Zuzana Zemanová Gitte Kerndrup Marry van den Heuvel-Eibrink Vincent van der Velden Charlotte Niemeyer Tomáš Kalina Jan Trka Jan Starý Ondřej Hrušák Ester Mejstříková

Haematologica 2016 06 24;101(6):707-16. Epub 2016 Mar 24.

CLIP-Department of Pediatric Hematology and Oncology, 2 Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic Department of Pediatric Hematology and Oncology, 2 Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic

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http://dx.doi.org/10.3324/haematol.2015.137711DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5013954PMC
June 2016

Exchange Transfusion and Leukapheresis in Pediatric Patients with AML With High Risk of Early Death by Bleeding and Leukostasis.

Authors:
Ursula Creutzig Claudia Rössig Michael Dworzak Jan Stary Arend von Stackelberg Wilhelm Wössmann Martin Zimmermann Dirk Reinhardt

Pediatr Blood Cancer 2016 Apr 16;63(4):640-5. Epub 2015 Dec 16.

Department of Pediatric Hematology-Oncology, University of Duisburg-Essen, Essen, Germany.

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http://dx.doi.org/10.1002/pbc.25855DOI Listing
April 2016

Fanconi anemia with biallelic FANCD1/BRCA2 mutations - Case report of a family with three affected children.

Authors:
Karel Svojgr David Sumerauer Alena Puchmajerova Ales Vicha Ondrej Hrusak Kyra Michalova Josef Malis Petr Smisek Martin Kyncl Drahuse Novotna Eva Machackova Jan Jencik Karel Pycha Miroslav Vaculik Roman Kodet Jan Stary

Eur J Med Genet 2016 Mar 2;59(3):152-7. Epub 2015 Dec 2.

Department of Pediatric Hematology and Oncology, Charles University in Prague, Second Faculty of Medicine and University Hospital Motol, Prague, Czech Republic.

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http://dx.doi.org/10.1016/j.ejmg.2015.11.013DOI Listing
March 2016

Prevalence, clinical characteristics, and prognosis of GATA2-related myelodysplastic syndromes in children and adolescents.

Authors:
Marcin W Wlodarski Shinsuke Hirabayashi Victor Pastor Jan Starý Henrik Hasle Riccardo Masetti Michael Dworzak Markus Schmugge Marry van den Heuvel-Eibrink Marek Ussowicz Barbara De Moerloose Albert Catala Owen P Smith Petr Sedlacek Arjan C Lankester Marco Zecca Victoria Bordon Susanne Matthes-Martin Jonas Abrahamsson Jörn Sven Kühl Karl-Walter Sykora Michael H Albert Bartlomiej Przychodzien Jaroslaw P Maciejewski Stephan Schwarz Gudrun Göhring Brigitte Schlegelberger Annámaria Cseh Peter Noellke Ayami Yoshimi Franco Locatelli Irith Baumann Brigitte Strahm Charlotte M Niemeyer

Blood 2016 Mar 23;127(11):1387-97; quiz 1518. Epub 2015 Dec 23.

Division of Pediatric Hematology and Oncology, Department of Pediatrics and Adolescent Medicine, University of Freiburg, Freiburg, Germany; German Cancer Consortium, Freiburg, Germany, and German Cancer Research Center, Heidelberg, Germany;

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http://www.bloodjournal.org/content/bloodjournal/early/2015/
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http://dx.doi.org/10.1182/blood-2015-09-669937DOI Listing
March 2016

LIN28B overexpression defines a novel fetal-like subgroup of juvenile myelomonocytic leukemia.

Authors:
Hetty H Helsmoortel Silvia Bresolin Tim Lammens Hélène Cavé Peter Noellke Aurélie Caye Farzaneh Ghazavi Andrica de Vries Henrik Hasle Veerle Labarque Riccardo Masetti Jan Stary Marry M van den Heuvel-Eibrink Jan Philippé Nadine Van Roy Yves Benoit Frank Speleman Charlotte Niemeyer Christian Flotho Giuseppe Basso Geertruy Te Kronnie Pieter Van Vlierberghe Barbara De Moerloose

Blood 2016 Mar 28;127(9):1163-72. Epub 2015 Dec 28.

Department of Pediatric Hematology-Oncology and Stem Cell Transplantation, Ghent University Hospital, Ghent, Belgium;

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http://dx.doi.org/10.1182/blood-2015-09-667808DOI Listing
March 2016

[The prospects for children with acute lymphoblastic leukemia of being cured has increased in the Czech Republic in the 21st century to 90% - outcome of the ALL-IC BFM 2002 trial].

Authors:
Kateřina Zdráhalová Jaroslav Štěrba Jiří Domanský Bohumír Blažek Hana Ptoszková Vladimír Mihál Zbyněk Novák Jiří Hak Daniela Procházková Zdena Černá Pavel Timr Yahia Jabali Petr Sedláček Petr Smíšek Zuzana Zemanová Marie Jarošová Alena Houdková Ester Mejstříková Ondřej Hrušák Jan Zuna Iveta Janotová Jan Trka Jan Starý

Cas Lek Cesk 2015 ;154(2):79-89

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October 2015

The predictive strength of next-generation sequencing MRD detection for relapse compared with current methods in childhood ALL.

Authors:
Michaela Kotrova Katerina Muzikova Ester Mejstrikova Michaela Novakova Violeta Bakardjieva-Mihaylova Karel Fiser Jan Stuchly Mathieu Giraud Mikaël Salson Christiane Pott Monika Brüggemann Marc Füllgrabe Jan Stary Jan Trka Eva Fronkova

Blood 2015 Aug;126(8):1045-7

Childhood Leukaemia Investigation Prague (CLIP), Department of Pediatric Hematology/Oncology, 2nd Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic.

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http://dx.doi.org/10.1182/blood-2015-07-655159DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4551355PMC
August 2015

Somatic thrombopoietin (THPO) gene mutations in childhood myeloid leukemias.

Authors:
Maite E Houwing Eva A Koopman-Coenen Rogier Kersseboom Saskia Gooskens Inge M Appel Susan T C J M Arentsen-Peters Andrica C H de Vries Dirk Reinhardt Jan Stary André Baruchel Valerie de Haas Marjolein Blink Rob H Lopes Cardozo Rob Pieters C Michel Zwaan Marry M van den Heuvel-Eibrink

Int J Hematol 2015 Jul 3;102(1):140-3. Epub 2015 Mar 3.

Department of Pediatric Oncology/Hematology, Erasmus MC-Sophia Children's Hospital, Dr Molewaterplein 60, Room Na 16.13, 3015 GJ, Rotterdam, The Netherlands.

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http://link.springer.com/content/pdf/10.1007%2Fs12185-015-17
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http://link.springer.com/10.1007/s12185-015-1759-3
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July 2015

Reprogramming of B cell acute lymphoblastic leukemia cells: Do we need to shoot a moving target?

Authors:
Karel Fišer Lucie Slámová Jean-Pierre Bourquin Jan Trka Jan Starý Ondřej Hrušák Ester Mejstříková

Proc Natl Acad Sci U S A 2015 Jul 11;112(27):E3455. Epub 2015 Jun 11.

Childhood Leukemia Investigation Prague (CLIP), Second Faculty of Medicine, Charles University Prague and University Hospital Motol, 150 06 Prague, Czech Republic;

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http://dx.doi.org/10.1073/pnas.1508680112DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4500239PMC
July 2015

BCOR and BCORL1 mutations in pediatric acute myeloid leukemia.

Authors:
Jasmijn D E de Rooij Marry M van den Heuvel-Eibrink Malou C H Hermkens Lonneke J Verboon Susan T C J M Arentsen-Peters Maarten Fornerod Andre Baruchel Jan Stary Dirk Reinhardt Valerie de Haas Rob Pieters C Michel Zwaan

Haematologica 2015 May 16;100(5):e194-5. Epub 2015 Jan 16.

Department of Pediatric Oncology/Hematology, Erasmus MC-Sophia Children's Hospital, Rotterdam, The Netherlands

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http://dx.doi.org/10.3324/haematol.2014.117796DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4420230PMC
May 2015

Diffuse parenchymal lung disease as first clinical manifestation of GATA-2 deficiency in childhood.

Authors:
Tamara Svobodova Ester Mejstrikova Ulrich Salzer Martina Sukova Petr Hubacek Radoslav Matej Martina Vasakova Ludmila Hornofova Marcela Dvorakova Eva Fronkova Felix Votava Tomas Freiberger Petr Pohunek Jan Stary Ales Janda

BMC Pulm Med 2015 Feb 10;15. Epub 2015 Feb 10.

Center for Chronic Immunodeficiency (CCI), University Medical Center and University of Freiburg, Freiburg im Breisgau, Germany.

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http://bmcpulmmed.biomedcentral.com/articles/10.1186/s12890-
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http://dx.doi.org/10.1186/s12890-015-0006-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4340788PMC
February 2015

Criteria for evaluating response and outcome in clinical trials for children with juvenile myelomonocytic leukemia.

Authors:
Charlotte M Niemeyer Mignon L Loh Annamaria Cseh Todd Cooper Christopher C Dvorak Rebecca Chan Blanca Xicoy Ulrich Germing Seiji Kojima Atsushi Manabe Michael Dworzak Barbara De Moerloose Jan Starý Owen P Smith Riccardo Masetti Albert Catala Eva Bergstraesser Marek Ussowicz Oskana Fabri André Baruchel Hélène Cavé Michel Zwaan Franco Locatelli Henrik Hasle Marry M van den Heuvel-Eibrink Christian Flotho Ayami Yoshimi

Haematologica 2015 Jan;100(1):17-22

Department of Pediatrics and Adolescent Medicine, Division of Pediatric Hematology and Oncology University of Freiburg, Germany.

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http://dx.doi.org/10.3324/haematol.2014.109892DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4281308PMC
January 2015

Homeobox gene expression in acute myeloid leukemia is linked to typical underlying molecular aberrations.

Authors:
Karolina Skvarova Kramarzova Karel Fiser Ester Mejstrikova Katerina Rejlova Marketa Zaliova Maarten Fornerod Harry A Drabkin Marry M van den Heuvel-Eibrink Jan Stary Jan Trka Julia Starkova

J Hematol Oncol 2014 Dec 24;7:94. Epub 2014 Dec 24.

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http://jhoonline.biomedcentral.com/articles/10.1186/s13045-0
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http://dx.doi.org/10.1186/s13045-014-0094-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4310032PMC
December 2014

An unusual case of high hyperdiploid childhood ALL with cryptic BCR/ABL1 rearrangement.

Authors:
Libuse Lizcova Zuzana Zemanova Halka Lhotska Jan Zuna Lenka Hovorkova Ester Mejstrikova Eva Malinova Jana Rabasova Ivan Raska Lucie Sramkova Jan Stary Kyra Michalova

Mol Cytogenet 2014 24;7(1):72. Epub 2014 Oct 24.

Center of Oncocytogenetics, Institute of Medical Biochemistry and Laboratory Diagnostics, General University Hospital in Prague and First Faculty of Medicine, Charles University in Prague, Prague, Czech Republic.

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http://dx.doi.org/10.1186/s13039-014-0072-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4213530PMC
October 2014

Combination of prednisolone and low dosed dexamethasone exhibits greater in vitro antileukemic activity than equiactive dose of prednisolone and overcomes prednisolone drug resistance in acute childhood lymphoblastic leukemia.

Authors:
Michaela Spenerova Petr Dzubak Josef Srovnal Lenka Radova Renata Burianova Petr Konecny Sona Salkova Zbynek Novak Dagmar Pospisilova Jan Stary Bohumir Blazek Jiri Hak Tomas Votava Pavel Timr Emilia Kaiserova Eva Bubanska Vladimir Mihal Marian Hajduch

Biomed Pap Med Fac Univ Palacky Olomouc Czech Repub 2014 Sep 31;158(3):422-7. Epub 2012 Oct 31.

Laboratory of Experimental Medicine, Institute of Molecular and Translational Medicine, Faculty of Medicine and Dentistry, Palacky University Olomouc and University Hospital Olomouc, Czech Republic.

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http://dx.doi.org/10.5507/bp.2012.059DOI Listing
September 2014

RASA4 undergoes DNA hypermethylation in resistant juvenile myelomonocytic leukemia.

Authors:
Anna R Poetsch Daniel B Lipka Tania Witte Rainer Claus Peter Nöllke Manuela Zucknick Christiane Olk-Batz Silvia Fluhr Michael Dworzak Barbara De Moerloose Jan Starý Marco Zecca Henrik Hasle Markus Schmugge Marry M van den Heuvel-Eibrink Franco Locatelli Charlotte M Niemeyer Christian Flotho Christoph Plass

Epigenetics 2014 Sep 31;9(9):1252-60. Epub 2014 Jul 31.

Division of Epigenomics and Cancer Risk Factors (C010); German Cancer Research Center; Heidelberg, Germany; The German Cancer Consortium; Heidelberg, Germany.

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http://dx.doi.org/10.4161/epi.29941DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4169017PMC
September 2014

Mapping epigenetic regulator gene mutations in cytogenetically normal pediatric acute myeloid leukemia.

Authors:
Daria G Valerio Jenny E Katsman-Kuipers Joop H Jansen Lonneke J Verboon Valerie de Haas Jan Stary André Baruchel Martin Zimmermann Rob Pieters Dirk Reinhardt Marry M van den Heuvel-Eibrink C Michel Zwaan

Haematologica 2014 Aug 9;99(8):e130-2. Epub 2014 May 9.

Department of Pediatric Oncology, Erasmus MC-Sophia Children's Hospital, Rotterdam, the Netherlands

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http://dx.doi.org/10.3324/haematol.2013.094565DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4116843PMC
August 2014

Augmenting clinical interpretability of thiopurine methyltransferase laboratory evaluation.

Authors:
Regina Demlova Martina Mrkvicova Jaroslav Sterba Hana Bernatikova Jan Stary Martina Sukova Alena Mikuskova Alica Chocholova Beata Mladosievicova Andrea Soltysova Darina Behulova Katerina Pilatova Lenka Zdrazilova-Dubska Dalibor Valik

Oncology 2014 12;86(3):152-8. Epub 2014 Mar 12.

Department of Pharmacology, Masaryk University School of Medicine, Brno, Czech Republic.

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http://dx.doi.org/10.1159/000357407DOI Listing
June 2014

Comparison of horse and rabbit antithymocyte globulin in immunosuppressive therapy for refractory cytopenia of childhood.

Authors:
Ayami Yoshimi Marry M van den Heuvel-Eibrink Irith Baumann Stephan Schwarz Ingrid Simonitsch-Klupp Pascale de Paepe Vit Campr Gitte Birk Kerndrup Maureen O'Sullivan Rita Devito Roos Leguit Miguel Hernandez Michael Dworzak Barbara de Moerloose Jan Stary Henrik Hasle Owen P Smith Marco Zecca Albert Catala Markus Schmugge Franco Locatelli Monika Führer Alexandra Fischer Anne Guderle Peter Nöllke Brigitte Strahm Charlotte M Niemeyer

Haematologica 2014 Apr 25;99(4):656-63. Epub 2013 Oct 25.

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http://dx.doi.org/10.3324/haematol.2013.095786DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3971075PMC
April 2014

Molecular biology of testicular germ cell tumors: unique features awaiting clinical application.

Authors:
Ludmila Boublikova Tomas Buchler Jan Stary Jitka Abrahamova Jan Trka

Crit Rev Oncol Hematol 2014 Mar 11;89(3):366-85. Epub 2013 Oct 11.

Department of Pediatric Hematology and Oncology, 2nd Faculty of Medicine, Charles University and University Hospital in Motol, Prague, Czech Republic.

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http://dx.doi.org/10.1016/j.critrevonc.2013.10.001DOI Listing
March 2014

Cytokines, growth, and environment factors in bone marrow plasma of acute lymphoblastic leukemia pediatric patients.

Authors:
Martin Kováč Martina Vášková Denisa Petráčková Vendula Pelková Ester Mejstříková Tomáš Kalina Markéta Žaliová Jaroslav Weiser Jan Starý Ondřej Hrušák

Eur Cytokine Netw 2014 Mar;25(1):8-13

CLIP - Childhood Leukemia Investigation Prague, Department of Pediatric Hematology and Oncology, 2nd Faculty of Medicine, Charles University and University Hospital Motol, Prague, Czech Republic.

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http://link.springer.com/content/pdf/10.1684%2Fecn.2014.0348
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http://dx.doi.org/10.1684/ecn.2014.0348DOI Listing
March 2014

Intensive chemotherapy for childhood acute lymphoblastic leukemia: results of the randomized intercontinental trial ALL IC-BFM 2002.

Authors:
Jan Stary Martin Zimmermann Myriam Campbell Luis Castillo Eduardo Dibar Svetlana Donska Alejandro Gonzalez Shai Izraeli Dragana Janic Janez Jazbec Josip Konja Emilia Kaiserova Jerzy Kowalczyk Gabor Kovacs Chi-Kong Li Edina Magyarosy Alexander Popa Batia Stark Yahia Jabali Jan Trka Ondrej Hrusak Hansjörg Riehm Giuseppe Masera Martin Schrappe

J Clin Oncol 2014 Jan 16;32(3):174-84. Epub 2013 Dec 16.

Jan Stary, Jan Trka, and Ondrej Hrusak, Charles University and University Hospital Motol, Prague; Yahia Jabali, Regional Hospital, Ceske Budejovice, Czech Republic; Martin Zimmermann and Hansjörg Riehm, Medical School Hannover, Hannover; Martin Schrappe, University Hospital Schleswig-Holstein, Kiel, Germany; Myriam Campbell, Roberto del Rio Hospital, Universidad de Chile, Santiago, Chile; Luis Castillo, Hospital Pereira Rossell, Montevideo, Uruguay; Eduardo Dibar, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina; Svetlana Donska, Regional Oncologic Hospital, Kiev, Ukraine; Alejandro Gonzalez, Institute of Hematology and Immunology, La Habana, Cuba; Shai Izraeli, Sheba Medical Center of Israel, Sackler School of Medicine, Tel Aviv University, Tel Hashomer; Batia Stark, Schneider Children's Medical Center of Israel, Sackler School of Medicine, Tel Aviv University, Petah-Tikva, Israel; Dragana Janic, University Children's Hospital, University of Belgrade, Belgrade, Serbia; Janez Jazbec, University Children's Hospital, Ljubljana, Slovenia; Josip Konja, University Hospital Centre Rebro, Zagreb, Croatia; Emilia Kaiserova, University Children's Hospital, Bratislava, Slovakia; Jerzy Kowalczyk, University of Lublin, Lublin, Poland; Gabor Kovacs and Edina Magyarosy, Semmelweis University, Budapest, Hungary; Chi-Kong Li, Prince of Wales Hospital, The Chinese University of Hong Kong, Shatin, Hong Kong, Special Administrative Region, People's Republic of China; Alexander Popa, N.N. Blokhin Russian Cancer Research Center, Moscow, Russia; and Giuseppe Masera, Ospedale S. Gerardo, University of Milano-Bicocca, Monza, Italy.

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http://dx.doi.org/10.1200/JCO.2013.48.6522DOI Listing
January 2014

Expression of the active caspase-3 in children and adolescents with classical Hodgkin lymphoma.

Authors:
Michaela Cepelová Kateřina Kamarádová Edita Kabíčková Jan Starý Eliška Cumlivská Roman Kodet Petr Gajdoš

Cesk Patol 2014 Jan;50(1):40-4

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January 2014

Randomized trial comparing liposomal daunorubicin with idarubicin as induction for pediatric acute myeloid leukemia: results from Study AML-BFM 2004.

Authors:
Ursula Creutzig Martin Zimmermann Jean-Pierre Bourquin Michael N Dworzak Gudrun Fleischhack Norbert Graf Thomas Klingebiel Bernhard Kremens Thomas Lehrnbecher Christine von Neuhoff Jörg Ritter Annette Sander André Schrauder Arend von Stackelberg Jan Starý Dirk Reinhardt

Blood 2013 Jul 23;122(1):37-43. Epub 2013 May 23.

Pediatric Hematology/Oncology, Hannover Medical School, Hannover, Germany.

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http://www.bloodjournal.org/content/early/2013/05/23/blood-2
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http://www.bloodjournal.org/cgi/doi/10.1182/blood-2013-02-48
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July 2013

Ikaros (IKZF1) alterations and minimal residual disease at day 15 assessed by flow cytometry predict prognosis of childhood BCR/ABL-negative acute lymphoblastic leukemia.

Authors:
Jana Volejnikova Ester Mejstrikova Petra Dörge Barbara Meissner Olga Zimmermannova Karel Svojgr Martin Stanulla Gunnar Cario Martin Schrappe Jan Stary Ondrej Hrusak Jan Trka Eva Fronkova

Pediatr Blood Cancer 2013 Mar 19;60(3):420-7. Epub 2012 Sep 19.

2nd Faculty of Medicine, Department of Pediatric Hematology and Oncology, Charles University and University Hospital Motol, Prague, Czech Republic.

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http://dx.doi.org/10.1002/pbc.24299DOI Listing
March 2013

Optimizing asparaginase therapy for acute lymphoblastic leukemia.

Authors:
Carmelo Rizzari Valentino Conter Jan Starý Antonella Colombini Anja Moericke Martin Schrappe

Curr Opin Oncol 2013 Mar;25 Suppl 1:S1-9

Department of Pediatrics, San Gerardo Hospital, University of Milano-Bicocca, Monza, Italy.

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http://dx.doi.org/10.1097/CCO.0b013e32835d7d85DOI Listing
March 2013

CBL mutations do not frequently occur in paediatric acute myeloid leukaemia.

Authors:
Eva A Coenen Emma M C Driessen C Michel Zwaan Jan Stary Andre Baruchel Valerie de Haas Eveline S J M de Bont Dirk Reinhardt Gertjan J L Kaspers Susan T C J M Arentsen-Peters Claus Meyer Rolf Marschalek Rob Pieters Ronald W Stam Marry M van den Heuvel-Eibrink

Br J Haematol 2012 Dec 1;159(5):577-84. Epub 2012 Oct 1.

Department of Paediatric Oncology/Haematology, Erasmus MC/Sophia Children's Hospital, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1111/bjh.12068DOI Listing
December 2012

Diagnosis and management of acute myeloid leukemia in children and adolescents: recommendations from an international expert panel.

Authors:
Ursula Creutzig Marry M van den Heuvel-Eibrink Brenda Gibson Michael N Dworzak Souichi Adachi Eveline de Bont Jochen Harbott Henrik Hasle Donna Johnston Akitoshi Kinoshita Thomas Lehrnbecher Guy Leverger Ester Mejstrikova Soheil Meshinchi Andrea Pession Susana C Raimondi Lillian Sung Jan Stary Christian M Zwaan Gertjan J L Kaspers Dirk Reinhardt

Blood 2012 Oct 9;120(16):3187-205. Epub 2012 Aug 9.

Department of Pediatric Hematology/Oncology, Medical School Hannover, Germany.

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October 2012

Imatinib after induction for treatment of children and adolescents with Philadelphia-chromosome-positive acute lymphoblastic leukaemia (EsPhALL): a randomised, open-label, intergroup study.

Authors:
Andrea Biondi Martin Schrappe Paola De Lorenzo Anders Castor Giovanna Lucchini Virginie Gandemer Rob Pieters Jan Stary Gabriele Escherich Myriam Campbell Chi-Kong Li Ajay Vora Maurizio Aricò Silja Röttgers Vaskar Saha Maria Grazia Valsecchi

Lancet Oncol 2012 Sep 14;13(9):936-45. Epub 2012 Aug 14.

Department of Paediatrics, University of Milano-Bicocca, Monza, Italy.

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http://dx.doi.org/10.1016/S1470-2045(12)70377-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3431502PMC
September 2012

[Invasive mucormycosis in pediatric hematology patients--single-center experience from 2005-2010].

Authors:
Vanda Chrenková Petr Hubáček Barbora Weinbergerová Petr Sedláček Petra Keslová Edita Kabíčková Klára Pavlíčková Lucie Srámková Jiří Snajdauf Eliška Bébrová Otakar Nyč Jan Starý Petr Hamal

Klin Mikrobiol Infekc Lek 2012 Aug;18(4):102-8

Institute of Medical Microbiology, Charles University, 2nd Medical Faculty Prague.

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August 2012

Valproic acid triggers differentiation and apoptosis in AML1/ETO-positive leukemic cells specifically.

Authors:
Michal Zapotocky Ester Mejstrikova Karel Smetana Jan Stary Jan Trka Julia Starkova

Cancer Lett 2012 Jun 17;319(2):144-153. Epub 2012 Jan 17.

CLIP, Department of Pediatric Hematology and Oncology, Charles University, 2nd Medical School, Prague, Czech Republic.

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http://dx.doi.org/10.1016/j.canlet.2011.12.041DOI Listing
June 2012

The Czech National Diamond-Blackfan Anemia Registry: clinical data and ribosomal protein mutations update.

Authors:
Dagmar Pospisilova Jana Cmejlova Barbora Ludikova Jan Stary Zdena Cerna Jiri Hak Pavel Timr Kvetoslava Petrtylova Jan Blatny Samuel Vokurka Radek Cmejla

Blood Cells Mol Dis 2012 Apr 3;48(4):209-18. Epub 2012 Mar 3.

Department of Paediatrics, Palacky University, Olomouc, Czech Republic.

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http://linkinghub.elsevier.com/retrieve/pii/S107997961200032
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http://dx.doi.org/10.1016/j.bcmd.2012.02.002DOI Listing
April 2012

Spliceosomal gene aberrations are rare, coexist with oncogenic mutations, and are unlikely to exert a driver effect in childhood MDS and JMML.

Authors:
Shinsuke Hirabayashi Christian Flotho Jessica Moetter Michael Heuser Henrik Hasle Bernd Gruhn Thomas Klingebiel Felicitas Thol Brigitte Schlegelberger Irith Baumann Brigitte Strahm Jan Stary Franco Locatelli Marco Zecca Eva Bergstraesser Michael Dworzak Marry M van den Heuvel-Eibrink Barbara De Moerloose Seishi Ogawa Charlotte M Niemeyer Marcin W Wlodarski

Blood 2012 Mar 11;119(11):e96-9. Epub 2012 Jan 11.

Pediatric Hematology and Oncology, University of Freiburg, Freiburg, Germany.

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http://dx.doi.org/10.1182/blood-2011-12-395087DOI Listing
March 2012

Skin lesions in a boy with X-linked lymphoproliferative disorder: comparison of 5 SH2D1A deletion cases.

Authors:
Ester Mejstríková Ales Janda Ondrej Hrusák Hana Bucková Markéta Vlcková Miroslava Hancárová Tomás Freiberger Barbora Ravcuková Karel Vesely Lenka Fajkusová Lenka Kopecková David Sumerauer Edita Kabícková Anna Sedivá Jan Stary Zdenek Sedlácek

Pediatrics 2012 Feb 23;129(2):e523-8. Epub 2012 Jan 23.

Department of Pediatric Hematology and Oncology, Charles University 2nd Faculty of Medicine and University Hospital Motol, Prague, Czech Republic.

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http://dx.doi.org/10.1542/peds.2011-0870DOI Listing
February 2012

CNS irradiation in pediatric acute myleoid leukemia: equal results by 12 or 18 Gy in studies AML-BFM98 and 2004.

Authors:
Ursula Creutzig Martin Zimmermann Jean-Pierre Bourquin Michael N Dworzak Gudrun Fleischhack Christine von Neuhoff Annette Sander André Schrauder Arend von Stackelberg Joerg Ritter Jan Starý Dirk Reinhardt

Pediatr Blood Cancer 2011 Dec 7;57(6):986-92. Epub 2011 Apr 7.

Pediatric Hematology/Oncology, University Hospital Muenster, Muenster, Germany.

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http://dx.doi.org/10.1002/pbc.22955DOI Listing
December 2011

Minimal residual disease in peripheral blood at day 15 identifies a subgroup of childhood B-cell precursor acute lymphoblastic leukemia with superior prognosis.

Authors:
Jana Volejnikova Ester Mejstrikova Tatana Valova Leona Reznickova Ladislava Hodonska Vladimir Mihal Jaroslav Sterba Yahia Jabali Daniela Prochazkova Bohumir Blazek Jiri Hak Zdenka Cerna Ondrej Hrusak Jan Stary Jan Trka Eva Fronkova

Haematologica 2011 Dec 31;96(12):1815-21. Epub 2011 Aug 31.

Department of Pediatric Hematology and Oncology, Charles University, Prague, Czech Republic.

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http://dx.doi.org/10.3324/haematol.2011.042937DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3232264PMC
December 2011

Second induction with high-dose cytarabine and mitoxantrone: different impact on pediatric AML patients with t(8;21) and with inv(16).

Authors:
Ursula Creutzig Martin Zimmermann Jean-Pierre Bourquin Michael N Dworzak Christine von Neuhoff Annette Sander André Schrauder Andrea Teigler-Schlegel Jan Stary Selim Corbacioglu Dirk Reinhardt

Blood 2011 Nov 26;118(20):5409-15. Epub 2011 Sep 26.

Pediatric Hematology/Oncology, University Hospital Muenster, Muenster, Germany;

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http://dx.doi.org/10.1182/blood-2011-07-364661DOI Listing
November 2011

Integrative analysis of type-I and type-II aberrations underscores the genetic heterogeneity of pediatric acute myeloid leukemia.

Authors:
Brian V Balgobind Iris H I M Hollink Susan T C J M Arentsen-Peters Martin Zimmermann Jochen Harbott H Berna Beverloo Anne R M von Bergh Jacqueline Cloos Gertjan J L Kaspers Valerie de Haas Zuzana Zemanova Jan Stary Jean-Michel Cayuela Andre Baruchel Ursula Creutzig Dirk Reinhardt Rob Pieters C Michel Zwaan Marry M van den Heuvel-Eibrink

Haematologica 2011 Oct 26;96(10):1478-87. Epub 2011 Jul 26.

Department of Pediatric Oncology/Hematology, Erasmus MC-Sophia Children's Hospital, Rotterdam, The Netherlands.

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http://dx.doi.org/10.3324/haematol.2010.038976DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3186309PMC
October 2011

Prognostic significance of additional cytogenetic aberrations in 733 de novo pediatric 11q23/MLL-rearranged AML patients: results of an international study.

Authors:
Eva A Coenen Susana C Raimondi Jochen Harbott Martin Zimmermann Todd A Alonzo Anne Auvrignon H Berna Beverloo Myron Chang Ursula Creutzig Michael N Dworzak Erik Forestier Brenda Gibson Henrik Hasle Christine J Harrison Nyla A Heerema Gertjan J L Kaspers Anna Leszl Nathalia Litvinko Luca Lo Nigro Akira Morimoto Christine Perot Dirk Reinhardt Jeffrey E Rubnitz Franklin O Smith Jan Stary Irina Stasevich Sabine Strehl Takashi Taga Daisuke Tomizawa David Webb Zuzana Zemanova Rob Pieters C Michel Zwaan Marry M van den Heuvel-Eibrink

Blood 2011 Jun 6;117(26):7102-11. Epub 2011 May 6.

Department of Pediatric Oncology/Hematology, Erasmus MC-Sophia Children's Hospital, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1182/blood-2010-12-328302DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3143552PMC
June 2011

Jumping translocations in bone marrow cells of pediatric patients with hematologic malignancies: a rare cytogenetic phenomenon.

Authors:
Libuse Lizcova Zuzana Zemanova Eva Malinova Kyra Michalova Petr Smisek Jan Stary

Cancer Genet 2011 Jun;204(6):348-9

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http://dx.doi.org/10.1016/j.cancergen.2011.04.008DOI Listing
June 2011

Aberrant DNA methylation characterizes juvenile myelomonocytic leukemia with poor outcome.

Authors:
Christiane Olk-Batz Anna R Poetsch Peter Nöllke Rainer Claus Manuela Zucknick Inga Sandrock Tania Witte Brigitte Strahm Henrik Hasle Marco Zecca Jan Stary Eva Bergstraesser Barbara De Moerloose Monika Trebo Marry M van den Heuvel-Eibrink Dorota Wojcik Franco Locatelli Christoph Plass Charlotte M Niemeyer Christian Flotho

Blood 2011 May 15;117(18):4871-80. Epub 2011 Mar 15.

Department of Pediatrics and Adolescent Medicine, University Medical Center, Freiburg, Germany.

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http://dx.doi.org/10.1182/blood-2010-08-298968DOI Listing
May 2011

Evaluation of gene expression signatures predictive of cytogenetic and molecular subtypes of pediatric acute myeloid leukemia.

Authors:
Brian V Balgobind Marry M Van den Heuvel-Eibrink Renee X De Menezes Dirk Reinhardt Iris H I M Hollink Susan T J C M Arentsen-Peters Elisabeth R van Wering Gertjan J L Kaspers Jacqueline Cloos Evelien S J M de Bont Jean-Michel Cayuela Andre Baruchel Claus Meyer Rolf Marschalek Jan Trka Jan Stary H Berna Beverloo Rob Pieters C Michel Zwaan Monique L den Boer

Haematologica 2011 Feb 22;96(2):221-30. Epub 2010 Oct 22.

Erasmus MC-Sophia Children's Hospital, Department of Pediatric Oncology and Hematology, Room Sp2456, PO Box 2060, 3000 CB Rotterdam, Netherlands.

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http://dx.doi.org/10.3324/haematol.2010.029660DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3031689PMC
February 2011

TEL/AML1-positive patients lacking TEL exon 5 resemble canonical TEL/AML1 cases.

Authors:
Marketa Zaliova Claus Meyer Gunnar Cario Martina Vaskova Rolf Marschalek Jan Stary Jan Zuna Jan Trka

Pediatr Blood Cancer 2011 Feb 22;56(2):217-25. Epub 2010 Oct 22.

CLIP, Department of Pediatric Hematology and Oncology, 2nd Faculty of Medicine, Charles University Prague and University Hospital Motol, Prague, Czech Republic.

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http://dx.doi.org/10.1002/pbc.22686DOI Listing
February 2011

High IGSF4 expression in pediatric M5 acute myeloid leukemia with t(9;11)(p22;q23).

Authors:
Jenny E Kuipers Eva A Coenen Brian V Balgobind Jan Stary Andre Baruchel Valerie de Haas Eveline S J M de Bont Dirk Reinhardt Gertjan J L Kaspers Jacqueline Cloos Astrid A Danen-van Oorschot Monique L den Boer Rolf Marschalek Claus Meyer Rob Pieters C Michel Zwaan Marry M van den Heuvel-Eibrink

Blood 2011 Jan 2;117(3):928-35. Epub 2010 Nov 2.

Pediatric Oncology/Hematology, Erasmus MC/Sophia Children's Hospital, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1182/blood-2010-05-286138DOI Listing
January 2011

Complex karyotype newly defined: the strongest prognostic factor in advanced childhood myelodysplastic syndrome.

Authors:
Gudrun Göhring Kyra Michalova H Berna Beverloo David Betts Jochen Harbott Oskar A Haas Gitte Kerndrup Laura Sainati Eva Bergstraesser Henrik Hasle Jan Stary Monika Trebo Marry M van den Heuvel-Eibrink Marco Zecca Elisabeth R van Wering Alexandra Fischer Peter Noellke Brigitte Strahm Franco Locatelli Charlotte M Niemeyer Brigitte Schlegelberger

Blood 2010 Nov 27;116(19):3766-9. Epub 2010 Aug 27.

Institute of Cell and Molecular Pathology, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.1182/blood-2010-04-280313DOI Listing
November 2010

Childhood near-tetraploid acute lymphoblastic leukemia: an EGIL study on 36 cases.

Authors:
Petr Lemez Andishe Attarbaschi Marie C Béné Yves Bertrand Gianluigi Castoldi Erik Forestier Richard Garand Oskar A Haas Sandrine Kagialis-Girard Wolf-Dieter Ludwig Estella Matutes Ester Mejstríková Marie-Pierre Pages Winfried Pickl Anna Porwit Alberto Orfao Richard Schabath Jan Starý Herbert Strobl Pascaline Talmant Mars B van't Veer Zuzana Zemanová

Eur J Haematol 2010 Oct;85(4):300-8

Department of Hematology and Blood Transfusion, Hospital Jihlava, Jihlava, Czech Republic.

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http://dx.doi.org/10.1111/j.1600-0609.2010.01493.xDOI Listing
October 2010

Acute leukemias with ETV6/ABL1 (TEL/ABL) fusion: poor prognosis and prenatal origin.

Authors:
Jan Zuna Marketa Zaliova Katerina Muzikova Claus Meyer Libuse Lizcova Zuzana Zemanova Jana Brezinova Felix Votava Rolf Marschalek Jan Stary Jan Trka

Genes Chromosomes Cancer 2010 Oct;49(10):873-84

Department of Pediatric Hematology and Oncology, CLIP (Childhood Leukaemia Investigation Prague), Charles University Prague, 2nd Faculty of Medicine and University Hospital Motol, Prague, Czech Republic.

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http://dx.doi.org/10.1002/gcc.20796DOI Listing
October 2010

Improved outcome with hematopoietic stem cell transplantation in a poor prognostic subgroup of infants with mixed-lineage-leukemia (MLL)-rearranged acute lymphoblastic leukemia: results from the Interfant-99 Study.

Authors:
Georg Mann Andishe Attarbaschi Martin Schrappe Paola De Lorenzo Christina Peters Ian Hann Giulio De Rossi Maria Felice Birgitte Lausen Thierry Leblanc Tomasz Szczepanski Alina Ferster Gritta Janka-Schaub Jeffrey Rubnitz Lewis B Silverman Jan Stary Myriam Campbell Chi Kong Li Ram Suppiah Andrea Biondi Ajay Vora Maria Grazia Valsecchi Rob Pieters

Blood 2010 Oct 30;116(15):2644-50. Epub 2010 Jun 30.

Berlin-Frankfurt-Münster Study Group, Austria.

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http://dx.doi.org/10.1182/blood-2010-03-273532DOI Listing
October 2010

Adoptive immunotherapy, chemotherapy, and second allogeneic transplant in the treatment of post-transplant relapse of acute leukemia in children: a single center experience.

Authors:
Renata Formankova Petr Sedlacek Petra Keslová Lucie Sramkova Hana Zizkova Jan Stary

Leuk Lymphoma 2010 Oct;51(10):1936-40

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http://dx.doi.org/10.3109/10428194.2010.504873DOI Listing
October 2010

Germline CBL mutations cause developmental abnormalities and predispose to juvenile myelomonocytic leukemia.

Authors:
Charlotte M Niemeyer Michelle W Kang Danielle H Shin Ingrid Furlan Miriam Erlacher Nancy J Bunin Severa Bunda Jerry Z Finklestein Thomas A Gorr Parinda Mehta Irene Schmid Gabriele Kropshofer Selim Corbacioglu Peter J Lang Christoph Klein Paul-Gerhard Schlegel Andrea Heinzmann Michaela Schneider Jan Starý Marry M van den Heuvel-Eibrink Henrik Hasle Franco Locatelli Debbie Sakai Sophie Archambeault Leslie Chen Ryan C Russell Stephanie S Sybingco Michael Ohh Benjamin S Braun Christian Flotho Mignon L Loh

Nat Genet 2010 Sep 8;42(9):794-800. Epub 2010 Aug 8.

Department of Pediatrics and the Comprehensive Cancer Center, University of California, San Francisco, San Francisco, CA, United States.

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http://dx.doi.org/10.1038/ng.641DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4297285PMC
September 2010

A novel recurrent chromosomal aberration involving chromosome 7 in childhood myelodysplastic syndrome.

Authors:
Libuse Lizcova Zuzana Zemanova Eva Malinova Marie Jarosova Ester Mejstrikova Petr Smisek Dagmar Pospisilova Jan Stary Kyra Michalova

Cancer Genet Cytogenet 2010 Aug;201(1):52-6

Center of Oncocytogenetics, Institute of Clinical Biochemistry and Laboratory Diagnostics, General University Hospital and 1st Faculty of Medicine, Charles University in Prague, U Nemocnice 2, Prague, Czech Republic.

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http://dx.doi.org/10.1016/j.cancergencyto.2010.05.004DOI Listing
August 2010

Low frequency of MLL-partial tandem duplications in paediatric acute myeloid leukaemia using MLPA as a novel DNA screenings technique.

Authors:
Brian V Balgobind Iris H I M Hollink Dirk Reinhardt Elisabeth R van Wering Siebold S N de Graaf Andre Baruchel Jan Stary H Berna Beverloo Georgine E de Greef Rob Pieters C Michel Zwaan Marry M van den Heuvel-Eibrink

Eur J Cancer 2010 Jul 16;46(10):1892-9. Epub 2010 Mar 16.

Paediatric Oncology/Haematology, Erasmus MC/Sophia Children's Hospital, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1016/j.ejca.2010.02.019DOI Listing
July 2010

Prognosis of children with mixed phenotype acute leukemia treated on the basis of consistent immunophenotypic criteria.

Authors:
Ester Mejstrikova Jana Volejnikova Eva Fronkova Katerina Zdrahalova Tomas Kalina Jaroslav Sterba Yahia Jabali Vladimir Mihal Bohumir Blazek Zdena Cerna Daniela Prochazkova Jiri Hak Zuzana Zemanova Marie Jarosova Alexandra Oltova Petr Sedlacek Jiri Schwarz Jan Zuna Jan Trka Jan Stary Ondrej Hrusak

Haematologica 2010 Jun 9;95(6):928-35. Epub 2010 Feb 9.

CLIP-Childhood Leukemia Investigation Prague Department of Pediatric Hematology and Oncology, Charles University, 2ndFaculty of Medicine and University Hospital Motol, Prague, Czech Republic.

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http://dx.doi.org/10.3324/haematol.2009.014506DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2878790PMC
June 2010

Prognostic impact of specific chromosomal aberrations in a large group of pediatric patients with acute myeloid leukemia treated uniformly according to trial AML-BFM 98.

Authors:
Christine von Neuhoff Dirk Reinhardt Annette Sander Martin Zimmermann Jutta Bradtke David R Betts Zuzana Zemanova Jan Stary Jean-Pierre Bourquin Oskar A Haas Michael N Dworzak Ursula Creutzig

J Clin Oncol 2010 Jun 3;28(16):2682-9. Epub 2010 May 3.

Pediatric Hematology and Oncology, Medical School Hannover, Carl-Neuberg-Strasse 1, Hannover, Germany.

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http://dx.doi.org/10.1200/JCO.2009.25.6321DOI Listing
June 2010

Favourable outcome of patients with childhood acute promyelocytic leukaemia after treatment with reduced cumulative anthracycline doses.

Authors:
Ursula Creutzig Martin Zimmermann Michael Dworzak Christian Urban Günter Henze Bernhard Kremens Max Lakomek Jean-Pierre Bourquin Jan Stary Dirk Reinhardt

Br J Haematol 2010 May 8;149(3):399-409. Epub 2010 Mar 8.

University Children's Hospital, Department of Paediatric Haematology/Oncology, Muenster, Hannover, Germany.

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http://dx.doi.org/10.1111/j.1365-2141.2010.08107.xDOI Listing
May 2010

Granulocyte colony-stimulating factor (G-CSF) treatment of childhood acute myeloid leukemias that overexpress the differentiation-defective G-CSF receptor isoform IV is associated with a higher incidence of relapse.

Authors:
Stephanie Ehlers Christin Herbst Martin Zimmermann Nicole Scharn Manuela Germeshausen Nils von Neuhoff Christian Michel Zwaan Katarina Reinhardt Iris H Hollink Jan-Henning Klusmann Thomas Lehrnbecher Silja Roettgers Jan Stary Michael Dworzak Karl Welte Ursula Creutzig Dirk Reinhardt

J Clin Oncol 2010 May 20;28(15):2591-7. Epub 2010 Apr 20.

Department of Pediatric Hematology and Oncology, Medical School Hannover, Hannover, Germany.

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http://dx.doi.org/10.1200/JCO.2009.25.9010DOI Listing
May 2010

Gene expression-based classification as an independent predictor of clinical outcome in juvenile myelomonocytic leukemia.

Authors:
Silvia Bresolin Marco Zecca Christian Flotho Luca Trentin Andrea Zangrando Laura Sainati Jan Stary Barbara de Moerloose Henrik Hasle Charlotte M Niemeyer Geertruy Te Kronnie Franco Locatelli Giuseppe Basso

J Clin Oncol 2010 Apr 15;28(11):1919-27. Epub 2010 Mar 15.

Laboratory of Oncohematology, Department of Pediatrics, University of Padova, Pavia, Italy.

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http://dx.doi.org/10.1200/JCO.2009.24.4426DOI Listing
April 2010

Salvage treatment for children with refractory first or second relapse of acute myeloid leukaemia with gemtuzumab ozogamicin: results of a phase II study.

Authors:
Christian M Zwaan Dirk Reinhardt Martin Zimmerman Henrik Hasle Jan Stary Batia Stark Michael Dworzak Ursula Creutzig Gertjan J L Kaspers

Br J Haematol 2010 Mar 8;148(5):768-76. Epub 2009 Dec 8.

Department of Paediatric Oncology/Haematology, Sophia Children's Hospital, Erasmus Medical Centre, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1111/j.1365-2141.2009.08011.xDOI Listing
March 2010

Mitotic recombination and compound-heterozygous mutations are predominant NF1-inactivating mechanisms in children with juvenile myelomonocytic leukemia and neurofibromatosis type 1.

Authors:
Doris Steinemann Larissa Arning Inka Praulich Manfred Stuhrmann Henrik Hasle Jan Stary Brigitte Schlegelberger Charlotte M Niemeyer Christian Flotho

Haematologica 2010 Feb 16;95(2):320-3. Epub 2009 Dec 16.

Cell and Molecular Pathology, Hannover Medical School, Hannover, Germany.

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http://dx.doi.org/10.3324/haematol.2009.010355DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2817036PMC
February 2010

Bone marrow transplantation for inherited bone marrow failure syndromes.

Authors:
Parinda Mehta Franco Locatelli Jan Stary Franklin O Smith

Pediatr Clin North Am 2010 Feb;57(1):147-70

Cincinnati Children's Hospital Medical Center and the University of Cincinnati College of Medicine, 3333 Burnet Avenue, Cincinnati, OH 45229, USA.

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http://dx.doi.org/10.1016/j.pcl.2010.01.002DOI Listing
February 2010

Detection of residual B precursor lymphoblastic leukemia by uniform gating flow cytometry.

Authors:
Ester Mejstríková Eva Fronková Tomás Kalina Marek Omelka Drago Batinić Klara Dubravcić Klára Pospísilová Martina Vásková Drorit Luria Suk Hang Cheng Margaret Ng Yonna Leung Janos Kappelmayer Flora Kiss Shai Izraeli Batia Stark Martin Schrappe Jan Trka Jan Starý Ondrej Hrusák

Pediatr Blood Cancer 2010 Jan;54(1):62-70

CLIP-Childhood Leukemia Investigation Prague, Prague, Czech Republic.

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http://dx.doi.org/10.1002/pbc.22261DOI Listing
January 2010

A partial nontandem duplication of the MLL gene in four patients with acute myeloid leukemia.

Authors:
Iveta Sárová Jana Brezinová Zuzana Zemanová Libuse Lizcová Adéla Berková Silvia Izáková Eva Malinová Ota Fuchs Arnost Kostecka Dana Provazníková Jitka Filkuková Jacqueline Maaloufová Jan Starý Kyra Michalová

Cancer Genet Cytogenet 2009 Dec;195(2):150-6

Institute of Hematology and Blood Transfusion, U Nemocnice 1, 128 20 Prague 2, Czech Republic.

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http://dx.doi.org/10.1016/j.cancergencyto.2009.05.008DOI Listing
December 2009

Cytogenetic and array comparative genomic hybridization analysis of a series of hepatoblastomas.

Authors:
Eva Stejskalová Josef Malis Jirí Snajdauf Karel Pýcha Helena Urbánková Viera Bajciová Jan Starý Roman Kodet Marie Jarosová

Cancer Genet Cytogenet 2009 Oct;194(2):82-7

Department of Pediatric Hematology and Oncology, Oncocytogenetics, University Hospital-Motol, V Uvalu 84, 15006 Prague 5, Czech Republic.

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http://dx.doi.org/10.1016/j.cancergencyto.2009.06.001DOI Listing
October 2009