Publications by authors named "Jan Rupp"

138 Publications

A Mitochondrial Polymorphism Alters Immune Cell Metabolism and Protects Mice from Skin Inflammation.

Authors:
Paul Schilf Axel Künstner Michael Olbrich Silvio Waschina Beate Fuchs Christina E Galuska Anne Braun Kerstin Neuschütz Malte Seutter Katja Bieber Lars Hellberg Christian Sina Tamás Laskay Jan Rupp Ralf J Ludwig Detlef Zillikens Hauke Busch Christian D Sadik Misa Hirose Saleh M Ibrahim

Int J Mol Sci 2021 Jan 20;22(3). Epub 2021 Jan 20.

Luebeck Institute of Experimental Dermatology, University of Luebeck, 23562 Luebeck, Germany.

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January 2021

Complications of nasal and pharyngeal swabs - a relevant challenge of the COVID-19 pandemic?

Authors:
Bandik Föh Max Borsche Alexander Balck Stefan Taube Jan Rupp Christine Klein Alexander Katalinic

Eur Respir J 2020 Dec 10. Epub 2020 Dec 10.

Institute of Social Medicine and Epidemiology, University of Lübeck, Lübeck, Germany.

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December 2020

Longitudinal Multi-omics Analyses Identify Responses of Megakaryocytes, Erythroid Cells, and Plasmablasts as Hallmarks of Severe COVID-19.

Authors:
Joana P Bernardes Neha Mishra Florian Tran Thomas Bahmer Lena Best Johanna I Blase Dora Bordoni Jeanette Franzenburg Ulf Geisen Jonathan Josephs-Spaulding Philipp Köhler Axel Künstner Elisa Rosati Anna C Aschenbrenner Petra Bacher Nathan Baran Teide Boysen Burkhard Brandt Niklas Bruse Jonathan Dörr Andreas Dräger Gunnar Elke David Ellinghaus Julia Fischer Michael Forster Andre Franke Sören Franzenburg Norbert Frey Anette Friedrichs Janina Fuß Andreas Glück Jacob Hamm Finn Hinrichsen Marc P Hoeppner Simon Imm Ralf Junker Sina Kaiser Ying H Kan Rainer Knoll Christoph Lange Georg Laue Clemens Lier Matthias Lindner Georgios Marinos Robert Markewitz Jacob Nattermann Rainer Noth Peter Pickkers Klaus F Rabe Alina Renz Christoph Röcken Jan Rupp Annika Schaffarzyk Alexander Scheffold Jonas Schulte-Schrepping Domagoj Schunk Dirk Skowasch Thomas Ulas Klaus-Peter Wandinger Michael Wittig Johannes Zimmermann Hauke Busch Bimba F Hoyer Christoph Kaleta Jan Heyckendorf Matthijs Kox Jan Rybniker Stefan Schreiber Joachim L Schultze Philip Rosenstiel

Immunity 2020 12 26;53(6):1296-1314.e9. Epub 2020 Nov 26.

Institute of Clinical Molecular Biology, Kiel University and University Medical Center Schleswig-Holstein, 24105 Kiel, Germany. Electronic address:

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December 2020

Increased Regulatory T Cells Precede the Development of Bronchopulmonary Dysplasia in Preterm Infants.

Authors:
Julia Pagel Nele Twisselmann Tanja K Rausch Silvio Waschina Annika Hartz Magdalena Steinbeis Jonathan Olbertz Kathrin Nagel Alena Steinmetz Kirstin Faust Martin Demmert Wolfgang Göpel Egbert Herting Jan Rupp Christoph Härtel

Front Immunol 2020 30;11:565257. Epub 2020 Sep 30.

Department of Pediatrics, University of Lübeck, Lübeck, Germany.

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September 2020

Exposure to welding fumes suppresses the activity of T-helper cells.

Authors:
Jürgen Knobloch Swaantje Casjens Martin Lehnert Sarah D Yanik Sandra Körber Anne Lotz Jan Rupp Monika Raulf Wolfgang Zschiesche Tobias Weiss Juliane Kronsbein Andrea Koch Thomas Brüning Beate Pesch

Environ Res 2020 10 12;189:109913. Epub 2020 Jul 12.

Institute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr University Bochum (IPA); Bürkle-de-la-Camp-Platz 1, 44789 Bochum, Germany.

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October 2020

Crosstalk Between Autophagy and Hypoxia-Inducible Factor-1α in Antifungal Immunity.

Authors:
Tim Quäschling Dirk Friedrich George S Deepe Jan Rupp

Cells 2020 09 23;9(10). Epub 2020 Sep 23.

Department of Infectious Diseases and Microbiology, University of Lübeck, 23562 Lübeck, Germany.

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September 2020

Heavy Exposure of Children Aged 9-12 Years With Severe Acute Respiratory Syndrome Coronavirus 2 Did Not Lead to Infection.

Authors:
Enno Schmidt Katja Steinhagen Jan Rupp

J Pediatric Infect Dis Soc 2020 Nov;9(5):620-621

Department of Infectious Diseases and Microbiology, University of Lübeck, Lübeck, Germany.

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November 2020

Development of a Plasmid Shuttle Vector System for Genetic Manipulation of Chlamydia psittaci.

Authors:
Kensuke Shima Mary M Weber Christiane Schnee Konrad Sachse Nadja Käding Matthias Klinger Jan Rupp

mSphere 2020 08 26;5(4). Epub 2020 Aug 26.

Department of Infectious Diseases and Microbiology, University of Lübeck, Lübeck, Germany.

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August 2020

Sepsis related mortality of extremely low gestational age newborns after the introduction of colonization screening for multi-drug resistant organisms.

Authors:
Christoph Härtel Kirstin Faust Ingmar Fortmann Alexander Humberg Julia Pagel Clara Haug Reinhard Kühl Bettina Bohnhorst Sabine Pirr Dorothee Viemann Arne Simon Michael Zemlin Silvia Poralla Andreas Müller Natascha Köstlin-Gille Christian Gille Matthias Heckmann Jan Rupp Egbert Herting Wolfgang Göpel

Antimicrob Resist Infect Control 2020 08 26;9(1):144. Epub 2020 Aug 26.

Department of Pediatrics, University of Lübeck, Lübeck, Germany.

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August 2020

S100A8 and S100A9 Are Important for Postnatal Development of Gut Microbiota and Immune System in Mice and Infants.

Authors:
Maike Willers Thomas Ulas Lena Völlger Thomas Vogl Anna S Heinemann Sabine Pirr Julia Pagel Beate Fehlhaber Olga Halle Jennifer Schöning Sabine Schreek Ulrike Löber Morgan Essex Peter Hombach Simon Graspeuntner Marijana Basic Andre Bleich Katja Cloppenborg-Schmidt Sven Künzel Danny Jonigk Jan Rupp Gesine Hansen Reinhold Förster John F Baines Christoph Härtel Joachim L Schultze Sofia K Forslund Johannes Roth Dorothee Viemann

Gastroenterology 2020 Dec 15;159(6):2130-2145.e5. Epub 2020 Aug 15.

Department of Pediatric Pneumology, Allergology and Neonatology, Hannover Medical School, Hannover, Germany; Cluster of Excellence RESIST (EXC 2155), Hannover Medical School, Hannover, Germany; PRIMAL Consortium, Hannover Medical School, Hannover, Germany. Electronic address:

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December 2020

Vancomycin-resistant Enterococcus faecium colonizing patients on hospital admission in Germany: prevalence and molecular epidemiology.

Authors:
Kyriaki Xanthopoulou Silke Peter David Tobys Michael Behnke Ariane G Dinkelacker Simone Eisenbeis Jane Falgenhauer Linda Falgenhauer Moritz Fritzenwanker Hannah Gölz Georg Häcker Paul G Higgins Can Imirzalioglu Nadja Käding Winfried V Kern Evelyn Kramme Axel Kola Alexander Mischnik Siegbert Rieg Anna M Rohde Jan Rupp Evelina Tacconelli Maria J G T Vehreschild Sarah V Walker Petra Gastmeier Harald Seifert

J Antimicrob Chemother 2020 Oct;75(10):2743-2751

German Centre for Infection Research (DZIF), Braunschweig, Germany.

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October 2020

No SARS-CoV-2 detection in the German CAPNETZ cohort of community acquired pneumonia before COVID-19 peak in March 2020.

Authors:
Marcus Panning Julius Wiener Kathrin Rothe Jochen Schneider Mathias W Pletz Gernot Rohde Jan Rupp Martin Witzenrath Christoph D Spinner

Infection 2020 Dec 3;48(6):971-974. Epub 2020 Jul 3.

Department of Internal Medicine II, School of Medicine, Technical University Munich, University Hospital rechts der Isar, Munich, Germany.

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December 2020

Microbiota-associated risk factors for C. difficile acquisition in hospitalized patients: A prospective, multicentric study.

Authors:
Philipp Solbach Patrick Chhatwal Sabrina Woltemate Evelina Tacconelli Michael Buhl Ingo B Autenrieth Maria J G T Vehreschild Nathalie Jazmati Markus Gerhard Christoph K Stein-Thoeringer Jan Rupp Kurt Ulm Armin Ott Florian Lasch Armin Koch Michael P Manns Sebastian Suerbaum Oliver Bachmann

Clin Infect Dis 2020 Jun 26. Epub 2020 Jun 26.

Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany.

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June 2020

Pro-inflammatory cytokine ratios determine the clinical course of febrile neutropenia in children receiving chemotherapy.

Authors:
Mira Siegmund Julia Pagel Tasja Scholz Jan Rupp Christoph Härtel Melchior Lauten

Mol Cell Pediatr 2020 Jun 9;7(1). Epub 2020 Jun 9.

Department of Pediatrics, Pediatric Hematology and Oncology, University of Lübeck, 23538, Lübeck, Germany.

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June 2020

Dissimilarity of Airway and Lung Tissue Microbiota in Smokers undergoing Surgery for Lung Cancer.

Authors:
Lena Reinhold Andreas Möllering Sönke Wallis Emanuel Palade Kathrin Schäfer Daniel Drömann Jan Rupp Simon Graspeuntner Klaus Dalhoff

Microorganisms 2020 May 26;8(6). Epub 2020 May 26.

Medical Clinic III, University Hospital Schleswig-Holstein/Campus Lübeck, Ratzeburger Allee 160, 23562 Lübeck, Germany.

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May 2020

The phylogenetic landscape and nosocomial spread of the multidrug-resistant opportunist Stenotrophomonas maltophilia.

Authors:
Matthias I Gröschel Conor J Meehan Ivan Barilar Margo Diricks Aitor Gonzaga Matthias Steglich Oscar Conchillo-Solé Isabell-Christin Scherer Uwe Mamat Christian F Luz Katrien De Bruyne Christian Utpatel Daniel Yero Isidre Gibert Xavier Daura Stefanie Kampmeier Nurdyana Abdul Rahman Michael Kresken Tjip S van der Werf Ifey Alio Wolfgang R Streit Kai Zhou Thomas Schwartz John W A Rossen Maha R Farhat Ulrich E Schaible Ulrich Nübel Jan Rupp Joerg Steinmann Stefan Niemann Thomas A Kohl

Nat Commun 2020 04 27;11(1):2044. Epub 2020 Apr 27.

Molecular and Experimental Mycobacteriology, Research Center Borstel, Borstel, Germany.

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April 2020

Saccharin Supplementation Inhibits Bacterial Growth and Reduces Experimental Colitis in Mice.

Authors:
Annika Sünderhauf René Pagel Axel Künstner Anika E Wagner Jan Rupp Saleh M Ibrahim Stefanie Derer Christian Sina

Nutrients 2020 Apr 17;12(4). Epub 2020 Apr 17.

Institute of Nutritional Medicine and 1st Department of Medicine, Section of Nutritional Medicine, University Hospital Schleswig-Holstein, Campus Lübeck, 23538 Lübeck, Germany.

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April 2020

Chronic liver disease negatively affects outcome in hospitalised patients with community-acquired pneumonia.

Authors:
Carla Bellinghausen Mathias W Pletz Jan Rupp Martin Witzenrath Christoph Welsch Stefan Zeuzem Jonel Trebicka Gernot G U Rohde

Gut 2021 Jan 6;70(1):221-222. Epub 2020 Apr 6.

University Hospital Frankfurt - Department of Respiratory Medicine and Allergology, Goethe University Frankfurt, Frankfurt am Main, Germany.

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January 2021

Probiotics Are Beneficial to Extremely Low Gestational Age Infants Fed Human Milk.

Authors:
Ingmar Fortmann Janina Marißen Bastian Siller Juliane Spiegler Alexander Humberg Kathrin Hanke Kirstin Faust Julia Pagel Leila Eyvazzadeh Kim Brenner Claudia Roll Sabine Pirr Dorothee Viemann Dimitra Stavropoulou Philipp Henneke Birte Tröger Thorsten Körner Anja Stein Christoph Derouet Michael Zemlin Christian Wieg Jan Rupp Egbert Herting Wolfgang Göpel Christoph Härtel

Nutrients 2020 Mar 22;12(3). Epub 2020 Mar 22.

Department of Pediatrics, University of Lübeck, 23562 Lübeck, Germany.

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March 2020

[The new comprehension of pulmonary infections].

Authors:
Ruth Hörster Jan Rupp

Pneumologe (Berl) 2020 10;17(2):105-112. Epub 2019 Dec 10.

2Klinik für Infektiologie und Mikrobiologie, Universitätsklinikum Schleswig-Holstein/Campus Lübeck, Ratzeburger Allee 160, 23538 Lübeck, Deutschland.

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December 2019

Infection-driven activation of transglutaminase 2 boosts glucose uptake and hexosamine biosynthesis in epithelial cells.

Authors:
Benoit Maffei Marc Laverrière Yongzheng Wu Sébastien Triboulet Stéphanie Perrinet Magalie Duchateau Mariette Matondo Robert L Hollis Charlie Gourley Jan Rupp Jeffrey W Keillor Agathe Subtil

EMBO J 2020 04 5;39(8):e102166. Epub 2020 Mar 5.

Unité de Biologie cellulaire de l'infection microbienne, CNRS UMR3691, Institut Pasteur, Paris, France.

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April 2020

Immune checkpoint inhibitors and tuberculosis: an old disease in a new context.

Authors:
Ewan A Langan Victoria Graetz Judith Allerheiligen Detlef Zillikens Jan Rupp Patrick Terheyden

Lancet Oncol 2020 01;21(1):e55-e65

Department of Dermatology, University of Lübeck, Lübeck, Germany.

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January 2020

Pneumococcal conjugate serotype distribution and predominating role of serotype 3 in German adults with community-acquired pneumonia.

Authors:
Christina Forstner Martin Kolditz Miriam Kesselmeier Santiago Ewig Gernot Rohde Grit Barten-Neiner Jan Rupp Martin Witzenrath Tobias Welte Mathias W Pletz

Vaccine 2020 01 21;38(5):1129-1136. Epub 2019 Nov 21.

Institute of Infectious Diseases and Infection Control, Jena University Hospital, Jena, Germany; CAPNETZ STIFTUNG, Hannover, Germany.

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January 2020

Rate and Predictors of Bacteremia in Afebrile Community-Acquired Pneumonia.

Authors:
Christina Forstner Vladimir Patchev Gernot Rohde Jan Rupp Martin Witzenrath Tobias Welte Heinz Burgmann Mathias W Pletz

Chest 2020 03 26;157(3):529-539. Epub 2019 Oct 26.

Institute of Infectious Diseases and Infection Control, University Hospital, Jena, Germany; CAPNETZ Stiftung, Hannover, Germany.

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March 2020

Annexin V expression on CD4 T cells with regulatory function.

Authors:
Anna-Lena Bollinger Thomas Bollinger Jan Rupp Kensuke Shima Natalie Gross Laura Padayachy Rachel Chicheportiche Gisella L Puga Yung Jörg Dieter Seebach

Immunology 2020 02 20;159(2):205-220. Epub 2019 Nov 20.

Division of Immunology and Allergology, Department of Medicine, University Hospitals and Medical Faculty, Geneva, Switzerland.

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February 2020

Macrolide combination therapy for patients hospitalised with community-acquired pneumonia? An individualised approach supported by machine learning.

Authors:
Rainer König Xueqi Cao Marcus Oswald Christina Forstner Gernot Rohde Jan Rupp Martin Witzenrath Tobias Welte Martin Kolditz Mathias Pletz

Eur Respir J 2019 12 12;54(6). Epub 2019 Dec 12.

Institute of Infectious Diseases and Infection Control, Jena University Hospital, Jena, Germany

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December 2019

Maternally Inherited Differences within Mitochondrial Complex I Control Murine Healthspan.

Authors:
Misa Hirose Paul Schilf Kim Zarse Hauke Busch Georg Fuellen Olaf Jöhren Rüdiger Köhling Inke R König Barbara Richer Jan Rupp Markus Schwaninger Karsten Seeger Christian Sina Michael Ristow Saleh M Ibrahim

Genes (Basel) 2019 07 13;10(7). Epub 2019 Jul 13.

Luebeck Institute of Experimental Dermatology, University of Luebeck, 23562 Luebeck, Germany.

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July 2019

Prevalence and Etiology of Community-acquired Pneumonia in Immunocompromised Patients.

Authors:
Marta Francesca Di Pasquale Giovanni Sotgiu Andrea Gramegna Dejan Radovanovic Silvia Terraneo Luis F Reyes Jan Rupp Juan González Del Castillo Francesco Blasi Stefano Aliberti Marcos I Restrepo

Clin Infect Dis 2019 04;68(9):1482-1493

Division of Pulmonary Diseases and Critical Care Medicine, The University of Texas Health Science Center at San Antonio.

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April 2019

Elaborations on Corallopyronin A as a Novel Treatment Strategy Against Genital Chlamydial Infections.

Authors:
Nathalie Loeper Simon Graspeuntner Svea Ledig Inga Kaufhold Friederike Hoellen Andrea Schiefer Beate Henrichfreise Kenneth Pfarr Achim Hoerauf Kensuke Shima Jan Rupp

Front Microbiol 2019 7;10:943. Epub 2019 May 7.

Department of Infectious Diseases and Microbiology, University of Lübeck, Lübeck, Germany.

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May 2019

A Natural mtDNA Polymorphism in Complex III Is a Modifier of Healthspan in Mice.

Authors:
Misa Hirose Axel Künstner Paul Schilf Anna Katharina Tietjen Olaf Jöhren Patricia Huebbe Gerald Rimbach Jan Rupp Markus Schwaninger Hauke Busch Saleh M Ibrahim

Int J Mol Sci 2019 May 13;20(9). Epub 2019 May 13.

Luebeck Institute of Experimental Dermatology and Center for research of inflammatory skin disease (CRIS), University of Luebeck, 23562 Luebeck, Germany.

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May 2019