Jan Purrucker

Jan Purrucker

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Jan Purrucker

Jan Purrucker

Publications by authors named "Jan Purrucker"

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Antagonizing dabigatran by idarucizumab in cases of ischemic stroke or intracranial hemorrhage in Germany-Updated series of 120 cases.

Int J Stroke 2020 Jan 19:1747493019895654. Epub 2020 Jan 19.

Department for Neurology, Klinikum rechts der Isar, TU München, München, Germany.

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http://dx.doi.org/10.1177/1747493019895654DOI Listing
January 2020

Development and validation of the Heidelberg Neurological Triage System (HEINTS).

J Neurol 2019 Nov 18;266(11):2685-2698. Epub 2019 Jul 18.

Department of Neurology, Heidelberg University Hospital, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s00415-019-09472-0DOI Listing
November 2019

Collateral Scores in Acute Ischemic Stroke : A retrospective study assessing the suitability of collateral scores as standalone predictors of clinical outcome.

Clin Neuroradiol 2019 Nov 28. Epub 2019 Nov 28.

Department of Neuroradiology, Heidelberg University Hospital, Im Neuenheimer Feld 400, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s00062-019-00858-1DOI Listing
November 2019

Association of Surgical Hematoma Evacuation vs Conservative Treatment With Functional Outcome in Patients With Cerebellar Intracerebral Hemorrhage.

JAMA 2019 10;322(14):1392-1403

Department of Neurology, University of Erlangen-Nuremberg, Erlangen, Germany.

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http://dx.doi.org/10.1001/jama.2019.13014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6784768PMC
October 2019

Unexpected excessive apixaban exposure: case report of a patient with polymorphisms of multiple apixaban elimination pathways.

BMC Pharmacol Toxicol 2019 08 29;20(1):53. Epub 2019 Aug 29.

Department of Clinical Pharmacology and Pharmacoepidemiology, Heidelberg University Hospital, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.

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http://dx.doi.org/10.1186/s40360-019-0331-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6716843PMC
August 2019

Cerebral microbleeds and stroke risk after ischaemic stroke or transient ischaemic attack: a pooled analysis of individual patient data from cohort studies.

Authors:
Duncan Wilson Gareth Ambler Keon-Joo Lee Jae-Sung Lim Masayuki Shiozawa Masatoshi Koga Linxin Li Caroline Lovelock Hugues Chabriat Michael Hennerici Yuen Kwun Wong Henry Ka Fung Mak Luis Prats-Sánchez Alejandro Martínez-Domeño Shigeru Inamura Kazuhisa Yoshifuji Ethem Murat Arsava Solveig Horstmann Jan Purrucker Bonnie Yin Ka Lam Adrian Wong Young Dae Kim Tae-Jin Song Maarten Schrooten Robin Lemmens Sebastian Eppinger Thomas Gattringer Ender Uysal Zeynep Tanriverdi Natan M Bornstein Einor Ben Assayag Hen Hallevi Jun Tanaka Hideo Hara Shelagh B Coutts Lisa Hert Alexandros Polymeris David J Seiffge Philippe Lyrer Ale Algra Jaap Kappelle Rustam Al-Shahi Salman Hans R Jäger Gregory Y H Lip Heinrich P Mattle Leonidas D Panos Jean-Louis Mas Laurence Legrand Christopher Karayiannis Thanh Phan Sarah Gunkel Nicolas Christ Jill Abrigo Thomas Leung Winnie Chu Francesca Chappell Stephen Makin Derek Hayden David J Williams M Eline Kooi Dianne H K van Dam-Nolen Carmen Barbato Simone Browning Kim Wiegertjes Anil M Tuladhar Noortje Maaijwee Christine Guevarra Chathuri Yatawara Anne-Marie Mendyk Christine Delmaire Sebastian Köhler Robert van Oostenbrugge Ying Zhou Chao Xu Saima Hilal Bibek Gyanwali Christopher Chen Min Lou Julie Staals Régis Bordet Nagaendran Kandiah Frank-Erik de Leeuw Robert Simister Aad van der Lugt Peter J Kelly Joanna M Wardlaw Yannie Soo Felix Fluri Velandai Srikanth David Calvet Simon Jung Vincent I H Kwa Stefan T Engelter Nils Peters Eric E Smith Yusuke Yakushiji Dilek Necioglu Orken Franz Fazekas Vincent Thijs Ji Hoe Heo Vincent Mok Roland Veltkamp Hakan Ay Toshio Imaizumi Beatriz Gomez-Anson Kui Kai Lau Eric Jouvent Peter M Rothwell Kazunori Toyoda Hee-Joon Bae Joan Marti-Fabregas David J Werring

Lancet Neurol 2019 Jul 23;18(7):653-665. Epub 2019 May 23.

Stroke Research Centre, Department of Brain Repair and Rehabilitation, UCL Queen Square Institute of Neurology, London, UK. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S14744422193019
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http://dx.doi.org/10.1016/S1474-4422(19)30197-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6562236PMC
July 2019

Letter by Purrucker et al Regarding Article, "Door-In-Door-Out Time at Primary Stroke Centers May Predict Outcome for Emergent Large Vessel Occlusion Patients".

Stroke 2019 Jul 3;50(7):e212. Epub 2019 Jun 3.

Department of Neurology, Heidelberg University Hospital, Germany.

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http://dx.doi.org/10.1161/STROKEAHA.118.024791DOI Listing
July 2019

Rationale and design of the Registry of Acute Stroke Under Novel Oral Anticoagulants-prime (RASUNOA-prime).

Eur Stroke J 2019 Jun 17;4(2):181-188. Epub 2018 Dec 17.

Department of Neurology, Heidelberg University Hospital, Heidelberg, Germany.

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http://dx.doi.org/10.1177/2396987318812644DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6591762PMC
June 2019

Neuroimaging and clinical outcomes of oral anticoagulant-associated intracerebral hemorrhage.

Ann Neurol 2018 11 25;84(5):694-704. Epub 2018 Oct 25.

Stroke Research Centre, Department of Brain Repair and Rehabilitation, University College London Institute of Neurology and National Hospital for Neurology and Neurosurgery, London, United Kingdom, New Zealand Brain Research Institute, Christchurch, New Zealand.

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http://dx.doi.org/10.1002/ana.25342DOI Listing
November 2018

MR neurography biomarkers to characterize peripheral neuropathy in AL amyloidosis.

Neurology 2018 08 20;91(7):e625-e634. Epub 2018 Jul 20.

From the Department of Neuroradiology (J.K., S.H., T.H., M.P., M.B.), Amyloidosis Center Heidelberg (J.K., M.W., J.P., S.O.S., E.H., C.K., U.H.), Department of Neurology (M.W., J.P., E.H.), Division of Experimental Radiology, Department of Neuroradiology (S.H.), and Medical Department V (S.O.S., C.K., U.H.), Heidelberg University Hospital, Germany; Department of Neurology (J.M.H.), University of Michigan, Ann Arbor; and Department of Neuroradiology (M.P.), Würzburg University Hospital, Germany.

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http://dx.doi.org/10.1212/WNL.0000000000006002DOI Listing
August 2018

Coagulation Testing in Intracerebral Hemorrhage Related to Non-vitamin K Antagonist Oral Anticoagulants.

Neurocrit Care 2017 Oct;27(2):208-213

Department of Neurology, Heidelberg University Hospital, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s12028-017-0403-xDOI Listing
October 2017

Management of Spontaneous Intracerebral Hemorrhage.

Curr Neurol Neurosci Rep 2017 Sep 8;17(10):80. Epub 2017 Sep 8.

Department of Neurology, Heidelberg University Hospital, Heidelberg, Germany.

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http://dx.doi.org/10.1007/s11910-017-0783-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5590024PMC
September 2017

Sural nerve injury in familial amyloid polyneuropathy: MR neurography vs clinicopathologic tools.

Neurology 2017 Aug 5;89(5):475-484. Epub 2017 Jul 5.

From the Department of Neuroradiology (J.K., S.H., M.P., M.B.), Amyloidosis Center Heidelberg (J.K., U.H., J.C.P., C.K., S.O.S., E.H., A.V.K., M.W.), Department of Neuropathology (F.S.), Medical Department V (U.H., C.K., S.O.S.), Department of Neurology (J.C.P., E.H., M.W.), Division of Experimental Radiology (S.H.), Department of Neuroradiology, and Medical Department III (A.V.K.), Heidelberg University Hospital; CCU Neuropathology (F.S.), German Consortium for Translational Cancer Research, German Cancer Research Center, Heidelberg, Germany; Department of Neurology (J.M.H.), University of Michigan, Ann Arbor; Department of Pathology (C.R.), University of Kiel; and Department of Neuroradiology (M.P.), Würzburg University Hospital, Germany.

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http://dx.doi.org/10.1212/WNL.0000000000004178DOI Listing
August 2017

Outcome of intracerebral hemorrhage associated with different oral anticoagulants.

Neurology 2017 May 5;88(18):1693-1700. Epub 2017 Apr 5.

From the Stroke Research Center (D.W., C.S., D.J.W.) and Neuroradiological Academic Unit (H.R.J.), Department of Brain Repair and Rehabilitation, Institute of Neurology, and Department of Statistical Science (G.A.), UCL, London, UK; Stroke Center and Neurology (D.J.S., C.T., S.T.E.), University Hospital Basel, University of Basel, Switzerland; Ottawa Hospital Research Institute and University of Ottawa (G.B., D.D.), Canada; Department of Neurology (J.C.P., T.R.), Heidelberg University Hospital, Germany; Manchester Academic Health Sciences Center (O.A.S., A.R.P.-J.), Salford Royal NHS Foundation Trust, UK; Department of Neurology (H.S., A.M.), Helsinki University Hospital, Finland; Stroke Center & Department of Neurology (S.-J.Y., J.-S.J.), Department of Neurology, National Taiwan University Hospital, Taipei; Department of Medicine and neurology at the Royal Melbourne Hospital (T.Y.W., A.M.), University of Melbourne, Parkville, Australia; U1171-Degenerative & Vascular Cognitive Disorders (M.F., C.C.), Univ Lille, Inserm, CHU Lille, France; Department of Neurology (R.H., F.H.B.M.S., J.S.), Maastricht University Medical Center, the Netherlands; Department of Neurosciences (J.A.P., P.M.C.C.), Eastern Health, Melbourne, Australia; Division of Neurology, Department of Internal Medicine (J.T., Y.Y.), Saga University Faculty of Medicine, Japan; Division of Clinical Neurosciences (M.B., R.A.-S.S.), Center for Clinical Brain Sciences, School of Clinical Sciences, University of Edinburgh; Department of Stroke Medicine, Division of Brain Sciences (R.V.), Imperial College London, UK; and Neurorehabilitation Unit (S.T.E.), University of Basel and University Center for Medicine of Aging, Felix Platter Hospital, Switzerland.

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http://dx.doi.org/10.1212/WNL.0000000000003886DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5409844PMC
May 2017

Management of acute stroke in patients on oral anticoagulants.

Curr Opin Neurol 2017 02;30(1):1-7

aDepartment of Neurology, Heidelberg University Hospital, Heidelberg bDepartment of Neurology, Klinikum Frankfurt Höchst, Frankfurt, Germany.

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http://dx.doi.org/10.1097/WCO.0000000000000406DOI Listing
February 2017

Coagulation Testing in Acute Ischemic Stroke Patients Taking Non-Vitamin K Antagonist Oral Anticoagulants.

Stroke 2017 01 29;48(1):152-158. Epub 2016 Nov 29.

From the Department of Neurology, University Hospital, Heidelberg, Germany (J.C.P., T.R., S.K., R.V.); Institute of Clinical Epidemiology and Biometry, University of Würzburg, Germany (K.H., P.U.H.); Department of Neurology, University Hospital, Tübingen, Germany (S.P.); Department of Neurology, University Hospital, Würzburg, Germany (P.K., C.K.); Department of Neurology, University Hospital, Essen, Germany (C.K.); Department of Neurology, University Hospital, Münster, Germany (R.D.); Department of Neurology, University Hospital, Kiel, Germany (A.B.); Department of Neurology, Klinikum Ludwigshafen, Ludwigshafen, Germany (F.P.); Department of Neurology, University Hospital, Duesseldorf, Germany (S.J.); Department of Neurology, Rhoen Klinikum, Bad Neustadt, Germany (H.S.); the Comprehensive Heart Failure Center, and Clinical Trial Center, University Hospital Würzburg, Germany (P.U.H.); and Department of Stroke Medicine, Imperial College London, United Kingdom (R.V.).

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http://dx.doi.org/10.1161/STROKEAHA.116.014963DOI Listing
January 2017

Measuring non-vitamin K antagonist oral anticoagulant levels: When is it appropriate and which methods should be used?

Int J Stroke 2016 10 13;11(7):748-58. Epub 2016 Jul 13.

Department of Neurology, Heidelberg University Hospital, Heidelberg, Germany.

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http://dx.doi.org/10.1177/1747493016659671DOI Listing
October 2016

Treatment With Prothrombin Complex Concentrate to Enable Emergency Lumbar Puncture in Patients Receiving Vitamin K Antagonists.

Ann Emerg Med 2016 09 14;68(3):340-4. Epub 2016 Apr 14.

Department of Neurology, Heidelberg University Hospital, Heidelberg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.annemergmed.2016.03.003DOI Listing
September 2016

Asymmetry of deep medullary veins on susceptibility weighted MRI in patients with acute MCA stroke is associated with poor outcome.

PLoS One 2015 7;10(4):e0120801. Epub 2015 Apr 7.

University of Heidelberg, Department of Neuroradiology, INF 400, 69120 Heidelberg, Germany; German Cancer Research Center (DKFZ), Department of Radiology, INF 280, 69120 Heidelberg, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0120801PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4388537PMC
April 2016

Safety of Endovascular Thrombectomy in Patients Receiving Non-Vitamin K Antagonist Oral Anticoagulants.

Stroke 2016 Apr 1;47(4):1127-30. Epub 2016 Mar 1.

From the Departments of Neurology (J.C.P., T.R., S.K., P.A.R., R.V.) and Neuroradiology (M.W.), University Hospital Heidelberg, Heidelberg, Germany; Institute of Clinical Epidemiology and Biometry (K.H., P.U.H.), University of Würzburg, Würzburg, Germany; Department of Neurology, University Hospital Münster, Münster, Germany (R.D.); Department of Neurology (C.K.), and Comprehensive Heart Failure Center and Clinical Trial Center (P.U.H.), University Hospital Würzburg, Würzburg, Germany; Department of Neurology, University Hospital Kiel, Kiel, Germany (A.B.); Department of Neurology, University Hospital Mainz, Mainz, Germany (K.G.); Department of Neurology, University Hospital Mannheim, Mannheim, Germany (M.G.H.); Departments of Neuroradiology (K.L.) and Stroke Medicine (R.V.), Imperial College London, London, United Kingdom; Department of Neurology, University Hospital Tübingen, Tübingen, Germany (S.P.); Department of Neurology, Asklepios Klinik Nord, Hamburg, Germany (G.S.); and Department of Neurology, Klinikum Fulda, Fulda, Germany (T.N.-H.).

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http://dx.doi.org/10.1161/STROKEAHA.116.012684DOI Listing
April 2016

Early Clinical and Radiological Course, Management, and Outcome of Intracerebral Hemorrhage Related to New Oral Anticoagulants.

JAMA Neurol 2016 Feb;73(2):169-77

Department of Neurology, Heidelberg University Hospital, Heidelberg, Germany9Department of Stroke Medicine, Imperial College London, London, England.

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http://dx.doi.org/10.1001/jamaneurol.2015.3682DOI Listing
February 2016

Comparison of stroke recognition and stroke severity scores for stroke detection in a single cohort.

J Neurol Neurosurg Psychiatry 2015 Sep 2;86(9):1021-8. Epub 2014 Dec 2.

Department of Neurology, Heidelberg University Hospital, Heidelberg, Germany Department of Neurology & Stroke, Tübingen University, Tübingen, Germany.

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http://jnnp.bmj.com/content/early/2014/12/22/jnnp-2014-30926
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http://jnnp.bmj.com/lookup/doi/10.1136/jnnp-2014-309260
Publisher Site
http://dx.doi.org/10.1136/jnnp-2014-309260DOI Listing
September 2015

Serum protein S100β is a diagnostic biomarker for distinguishing posterior circulation stroke from vertigo of nonvascular causes.

Eur Neurol 2014 16;72(5-6):278-84. Epub 2014 Oct 16.

Department of Neurology, Heidelberg University Hospital, Heidelberg, Germany.

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http://dx.doi.org/10.1159/000363569DOI Listing
July 2015

[Register for acute strokes under new oral anticoagulants (RASUNOAprime)].

Dtsch Med Wochenschr 2015 Jun 11;140 Suppl 1:S10. Epub 2015 Jun 11.

Neurologische Klinik, Universität Heidelberg.

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http://dx.doi.org/10.1055/s-0041-101311DOI Listing
June 2015

In vivo detection of nerve injury in familial amyloid polyneuropathy by magnetic resonance neurography.

Brain 2015 Mar 18;138(Pt 3):549-62. Epub 2014 Dec 18.

1 Department of Neuroradiology, University of Heidelberg, Heidelberg, Germany 2 Amyloidosis Centre Heidelberg, University of Heidelberg, Heidelberg, Germany.

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https://academic.oup.com/brain/article-lookup/doi/10.1093/br
Publisher Site
http://dx.doi.org/10.1093/brain/awu344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4339768PMC
March 2015

Secondary hematoma expansion in intracerebral hemorrhage during rivaroxaban therapy.

Am J Emerg Med 2014 Aug 3;32(8):947.e3-5. Epub 2014 Feb 3.

Department of Neurology, Heidelberg University Hospital, Heidelberg, Germany.

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http://dx.doi.org/10.1016/j.ajem.2014.01.042DOI Listing
August 2014

Cerebral amyloid angiopathy--an underdiagnosed entity in younger adults with lobar intracerebral hemorrhage?

Amyloid 2013 Mar 12;20(1):45-7. Epub 2012 Dec 12.

Department of Neurology, Heidelberg University Hospital, Heidelberg, Germany.

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http://dx.doi.org/10.3109/13506129.2012.746937DOI Listing
March 2013

Targeting the epigenome: effects of epigenetic treatment strategies on genomic stability in healthy human cells.

Clin Epigenetics 2010 Sep 27;1(1-2):45-54. Epub 2010 Jul 27.

Division of Immunotherapy and Gene Therapy, José Carreras Center for Immunotherapy and Gene Therapy, Department of Internal Medicine, Saarland University Medical Center, 66421 Homburg/Saar, Germany.

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http://dx.doi.org/10.1007/s13148-010-0007-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365366PMC
September 2010

HDAC inhibition radiosensitizes human normal tissue cells and reduces DNA Double-Strand Break repair capacity.

Oncol Rep 2010 Jan;23(1):263-9

Division of Immunotherapy and Gene Therapy, Department of Internal Medicine I, José Carreras Research Center, Saarland University Medical Center, Homburg/Saar, Germany.

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January 2010