Jan Michiels

Jan Michiels

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Jan Michiels

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The Escherichia coli RnlA-RnlB toxin-antitoxin complex: production, characterization and crystallization.

Acta Crystallogr F Struct Biol Commun 2020 Jan 1;76(Pt 1):31-39. Epub 2020 Jan 1.

Structural Biology Brussels, Vrije Universiteit Brussel, Pleinlaan 2, B-1050 Brussels, Belgium.

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http://dx.doi.org/10.1107/S2053230X19017175DOI Listing
January 2020

GTP Binding is Necessary for the Activation of a Toxic Mutant Isoform of the Essential GTPase ObgE.

Int J Mol Sci 2019 Dec 18;21(1). Epub 2019 Dec 18.

Centre of Microbial and Plant Genetics, KU Leuven-University of Leuven, Kasteelpark Arenberg 20 box 2460, B-3001 Leuven, Belgium.

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http://dx.doi.org/10.3390/ijms21010016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6982127PMC
December 2019

Biochemical determinants of ObgE-mediated persistence.

Mol Microbiol 2019 11 18;112(5):1593-1608. Epub 2019 Sep 18.

Structural Biology Brussels, Vrije Universiteit Brussel, Pleinlaan 2, 1050, Brussels, Belgium.

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https://onlinelibrary.wiley.com/doi/abs/10.1111/mmi.14382
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http://dx.doi.org/10.1111/mmi.14382DOI Listing
November 2019

Enrichment of persisters enabled by a ß-lactam-induced filamentation method reveals their stochastic single-cell awakening.

Commun Biol 2019 29;2:426. Epub 2019 Nov 29.

1VIB Center for Microbiology, Flanders Institute for Biotechnology, Kasteelpark Arenberg 20 box 2460, 3001 Leuven, Belgium.

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http://dx.doi.org/10.1038/s42003-019-0672-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6884588PMC
November 2019

Bacterial Heterogeneity and Antibiotic Survival: Understanding and Combatting Persistence and Heteroresistance.

Mol Cell 2019 10;76(2):255-267

Centre of Microbial and Plant Genetics, KU Leuven - University of Leuven, Leuven, Belgium; VIB-KU Leuven Center for Microbiology, Leuven, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2019.09.028DOI Listing
October 2019

HokB Monomerization and Membrane Repolarization Control Persister Awakening.

Mol Cell 2019 09 18;75(5):1031-1042.e4. Epub 2019 Jul 18.

Center for Microbiology, VIB, 3001 Leuven, Belgium; Centre of Microbial and Plant Genetics, KU Leuven, 3001 Leuven, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2019.06.015DOI Listing
September 2019

Antibiotics: Combatting Tolerance To Stop Resistance.

mBio 2019 09 10;10(5). Epub 2019 Sep 10.

VIB Center for Microbiology, Flanders Institute for Biotechnology, Leuven, Belgium

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http://dx.doi.org/10.1128/mBio.02095-19DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6737247PMC
September 2019

High-throughput time-resolved morphology screening in bacteria reveals phenotypic responses to antibiotics.

Commun Biol 2019 23;2:269. Epub 2019 Jul 23.

1Centre of Microbial and Plant Genetics, KU Leuven-University of Leuven, Leuven, 3001 Belgium.

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http://dx.doi.org/10.1038/s42003-019-0480-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6650389PMC
July 2019

General Mechanisms Leading to Persister Formation and Awakening.

Trends Genet 2019 Jun 27;35(6):401-411. Epub 2019 Apr 27.

Center for Microbiology, Vlaams Instituut voor Biotechnologie (VIB), Leuven 3000, Belgium; Center of Microbial and Plant Genetics, Katholieke Universiteit (KU) Leuven, Leuven 3000, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.tig.2019.03.007DOI Listing
June 2019

Experimental Design, Population Dynamics, and Diversity in Microbial Experimental Evolution.

Microbiol Mol Biol Rev 2018 09 25;82(3). Epub 2018 Jul 25.

Laboratory of Symbiotic and Pathogenic Interactions, Centre of Microbial and Plant Genetics, KU Leuven-University of Leuven, Leuven, Belgium

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http://dx.doi.org/10.1128/MMBR.00008-18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094045PMC
September 2018

The Putative De--acetylase DnpA Contributes to Intracellular and Biofilm-Associated Persistence of Exposed to Fluoroquinolones.

Front Microbiol 2018 10;9:1455. Epub 2018 Jul 10.

Pharmacologie Cellulaire et Moléculaire, Louvain Drug Research Institute, Université catholique de Louvain, Brussels, Belgium.

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http://dx.doi.org/10.3389/fmicb.2018.01455DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6048251PMC
July 2018

Stabbed while Sleeping: Synthetic Retinoid Antibiotics Kill Bacterial Persister Cells.

Mol Cell 2018 06 7;70(5):763-764. Epub 2018 Jun 7.

Centre of Microbial and Plant Genetics, KU Leuven, Kasteelpark Arenberg 20, Box 2460, 3001 Leuven, Belgium; Center for Microbiology, Vlaams Instituut voor Biotechnologie, Leuven, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.molcel.2018.05.029DOI Listing
June 2018

Fighting bacterial persistence: Current and emerging anti-persister strategies and therapeutics.

Drug Resist Updat 2018 05 10;38:12-26. Epub 2018 Apr 10.

Centre of Microbial and Plant Genetics, KU Leuven, Kasteelpark Arenberg 20, Box 2460, 3001 Leuven, Belgium; Center for Microbiology, Vlaams Instituut voor Biotechnologie, Leuven, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.drup.2018.03.002DOI Listing
May 2018

An integrative view of cell cycle control in Escherichia coli.

FEMS Microbiol Rev 2018 03;42(2):116-136

Centre of Microbial and Plant Genetics, KU Leuven-University of Leuven, B-3001 Leuven, Belgium.

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http://dx.doi.org/10.1093/femsre/fuy005DOI Listing
March 2018

Hitting with a BAM: Selective Killing by Lectin-Like Bacteriocins.

mBio 2018 03 20;9(2). Epub 2018 Mar 20.

Centre of Microbial and Plant Genetics, KU Leuven, Heverlee, Belgium.

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http://dx.doi.org/10.1128/mBio.02138-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874912PMC
March 2018

Network-Based Identification of Adaptive Pathways in Evolved Ethanol-Tolerant Bacterial Populations.

Mol Biol Evol 2017 Nov;34(11):2927-2943

Department of Information Technology, IDLab, IMEC, Ghent University, Gent, Belgium.

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http://dx.doi.org/10.1093/molbev/msx228DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5850225PMC
November 2017

Diagnostic Differentiation of von Willebrand Disease Types 1 and 2 by von Willebrand Factor Multimer Analysis and DDAVP Challenge Test.

Clin Appl Thromb Hemost 2017 Sep 21;23(6):518-531. Epub 2016 Jul 21.

2 Hemostasis Research Unit, Department of Hematology, Antwerp University Hospital, Belgium.

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http://dx.doi.org/10.1177/1076029616647157DOI Listing
September 2017

Formation, physiology, ecology, evolution and clinical importance of bacterial persisters.

FEMS Microbiol Rev 2017 05;41(3):219-251

KU Leuven-University of Leuven, Centre of Microbial and Plant Genetics, Kasteelpark Arenberg 20, Box 2460, B-3001 Leuven, Belgium.

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http://dx.doi.org/10.1093/femsre/fux001DOI Listing
May 2017

Structural and biochemical analysis of ObgE, a central regulator of bacterial persistence.

J Biol Chem 2017 04 21;292(14):5871-5883. Epub 2017 Feb 21.

From the Structural Biology Brussels, Vrije Universiteit Brussel, 1050 Brussels,

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http://dx.doi.org/10.1074/jbc.M116.761809DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5392579PMC
April 2017

Repurposing AM404 for the treatment of oral infections by Porphyromonas gingivalis.

Clin Exp Dent Res 2017 Apr 7;3(2):69-76. Epub 2017 Apr 7.

Department of Microbial and Molecular Systems KU Leuven, Centre of Microbial and Plant Genetics Leuven Belgium.

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http://dx.doi.org/10.1002/cre2.65DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5719815PMC
April 2017

Repurposing Toremifene for Treatment of Oral Bacterial Infections.

Antimicrob Agents Chemother 2017 03 23;61(3). Epub 2017 Feb 23.

KU Leuven, Centre of Microbial and Plant Genetics, Department of Microbial and Molecular Systems, Leuven, Belgium

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http://dx.doi.org/10.1128/AAC.01846-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5328575PMC
March 2017

New approaches to combat biofilms.

J Oral Microbiol 2017 15;9(1):1300366. Epub 2017 Mar 15.

Department of Microbial and Molecular Systems, KU Leuven, Centre of Microbial and Plant Genetics, Leuven, Belgium.

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http://dx.doi.org/10.1080/20002297.2017.1300366DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405727PMC
March 2017

Molecular mechanisms and clinical implications of bacterial persistence.

Drug Resist Updat 2016 11 15;29:76-89. Epub 2016 Oct 15.

Centre of Microbial and Plant Genetics, KU Leuven, Leuven, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.drup.2016.10.002DOI Listing
November 2016

Measuring the Viscosity of the Escherichia coli Plasma Membrane Using Molecular Rotors.

Biophys J 2016 Oct;111(7):1528-1540

Department of Chemistry, Imperial College London, London, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.bpj.2016.08.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052448PMC
October 2016

Safe Exclusion of Deep Vein Thrombosis by a Rapid Sensitive ELISA D-dimer and Compression Ultrasonography in 1330 Outpatients With Suspected DVT.

Angiology 2016 09 13;67(8):781-7. Epub 2015 Dec 13.

Thrombosis and Hemostasis Research, Department of Hematology, University Hospital Antwerp, Antwerp, Belgium.

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http://dx.doi.org/10.1177/0003319715616007DOI Listing
September 2016

Membrane localization and topology of the DnpA protein control fluoroquinolone tolerance in Pseudomonas aeruginosa.

FEMS Microbiol Lett 2016 09 31;363(17). Epub 2016 Jul 31.

Centre of Microbial and Plant Genetics, KU Leuven, 3001 Leuven, Belgium

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http://dx.doi.org/10.1093/femsle/fnw184DOI Listing
September 2016

Draft genome sequence of Acinetobacter baumannii strain NCTC 13423, a multidrug-resistant clinical isolate.

Stand Genomic Sci 2016 1;11(1):57. Epub 2016 Sep 1.

Centre of Microbial and Plant Genetics, KU Leuven, B-3001 Leuven, Belgium.

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http://dx.doi.org/10.1186/s40793-016-0181-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009669PMC
September 2016

Draft genome sequence of Enterococcus faecium strain LMG 8148.

Stand Genomic Sci 2016 7;11(1):63. Epub 2016 Sep 7.

Centre of Microbial and Plant Genetics, KU Leuven, B-3001 Leuven, Belgium.

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http://dx.doi.org/10.1186/s40793-016-0187-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5015329PMC
September 2016

Reactive oxygen species do not contribute to ObgE*-mediated programmed cell death.

Sci Rep 2016 09 19;6:33723. Epub 2016 Sep 19.

Centre of Microbial and Plant Genetics, KU Leuven - University of Leuven, 3001 Leuven, Belgium.

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http://dx.doi.org/10.1038/srep33723DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5027388PMC
September 2016

In Vitro Emergence of High Persistence upon Periodic Aminoglycoside Challenge in the ESKAPE Pathogens.

Antimicrob Agents Chemother 2016 08 22;60(8):4630-7. Epub 2016 Jul 22.

Centre of Microbial and Plant Genetics, KU Leuven, Leuven, Belgium

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http://dx.doi.org/10.1128/AAC.00757-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4958152PMC
August 2016

A study of SeqA subcellular localization in Escherichia coli using photo-activated localization microscopy.

Faraday Discuss 2015 9;184:425-50. Epub 2015 Oct 9.

Department of Chemistry, KU Leuven, Celestijnenlaan 200F, Box 2404, 3001 Heverlee, Belgium.

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http://dx.doi.org/10.1039/c5fd00058kDOI Listing
July 2016

A Historical Perspective on Bacterial Persistence.

Methods Mol Biol 2016 ;1333:3-13

Centre of Microbial and Plant Genetics (CMPG), Department of Microbial and Molecular Systems, KU Leuven - University of Leuven, Kasteelpark Arenberg 20, box 2460, 3001, Heverlee, Belgium.

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http://link.springer.com/10.1007/978-1-4939-2854-5_1
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http://dx.doi.org/10.1007/978-1-4939-2854-5_1DOI Listing
July 2016

Experimental Evolution of Escherichia coli Persister Levels Using Cyclic Antibiotic Treatments.

Methods Mol Biol 2016 ;1333:131-43

Centre of Microbial and Plant Genetics (CMPG), KU Leuven - University of Leuven, Leuven, 3001, Belgium.

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http://dx.doi.org/10.1007/978-1-4939-2854-5_12DOI Listing
July 2016

Should we develop screens for multi-drug antibiotic tolerance?

Expert Rev Anti Infect Ther 2016 07 8;14(7):613-6. Epub 2016 Jun 8.

a Centre of Microbial and Plant Genetics, Department of Molecular and Microbial Systems , KU Leuven, University of Leuven , Leuven , Belgium.

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http://dx.doi.org/10.1080/14787210.2016.1194754DOI Listing
July 2016

Symbiont abundance is more important than pre-infection partner choice in a Rhizobium - legume mutualism.

Syst Appl Microbiol 2016 Jul 30;39(5):345-9. Epub 2016 May 30.

Plant Conservation and Population Biology, Biology Department, KU Leuven, Kasteelpark Arenberg 31, B-3001 Leuven, Belgium.

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http://dx.doi.org/10.1016/j.syapm.2016.05.007DOI Listing
July 2016

Efficacy of Artilysin Art-175 against Resistant and Persistent Acinetobacter baumannii.

Antimicrob Agents Chemother 2016 06 23;60(6):3480-8. Epub 2016 May 23.

Laboratory of Gene Technology, Department of Biosystems, KU Leuven, Heverlee, Belgium Laboratory of Applied Biotechnology, Department of Applied Biosciences, Ghent University, Ghent, Belgium

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http://dx.doi.org/10.1128/AAC.00285-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4879360PMC
June 2016

The bacterial cell cycle checkpoint protein Obg and its role in programmed cell death.

Microb Cell 2016 Mar 16;3(6):255-256. Epub 2016 Mar 16.

Centre of Microbial and Plant Genetics, KU Leuven - University of Leuven, 3001 Leuven, Belgium.

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http://dx.doi.org/10.15698/mic2016.06.507DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5348993PMC
March 2016

Diagnosis, etiology and management of the Budd-Chiari Syndrome: a bloodcoagulation and hepatological study on the course of the disease treated with TIPS.

Int Angiol 2016 Feb 3;35(1):90-7. Epub 2015 Jul 3.

Fourth Department of Internal Medicine, Hematology, Faculty of Medicine in Hradec Kralove, University Hospital in Hradec Kralove, Hradec Kralove, Czech Republic -

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February 2016

A Single-Amino-Acid Substitution in Obg Activates a New Programmed Cell Death Pathway in Escherichia coli.

mBio 2015 Dec 22;6(6):e01935-15. Epub 2015 Dec 22.

Centre of Microbial and Plant Genetics, KU Leuven-University of Leuven, Leuven, Belgium Department of Life Science Technologies, Smart Systems and Emerging Technologies Unit, imec, Leuven, Belgium.

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http://mbio.asm.org/content/6/6/e01935-15.full.pdf
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http://mbio.asm.org/lookup/doi/10.1128/mBio.01935-15
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http://dx.doi.org/10.1128/mBio.01935-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4701833PMC
December 2015

Frequency-based haplotype reconstruction from deep sequencing data of bacterial populations.

Nucleic Acids Res 2015 Sep 18;43(16):e105. Epub 2015 May 18.

Department of Information Technology, Ghent University, iMinds, 9050 Gent, Belgium Department of Microbial and Molecular Systems, Centre of Microbial and Plant Genetics, KU Leuven, Kasteelpark Arenberg 20, 3001 Leuven, Belgium Department of Plant Biotechnology and Bioinformatics, Ghent University, 9052 Ghent, Belgium

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http://dx.doi.org/10.1093/nar/gkv478DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4652744PMC
September 2015

Myeloproliferative and thrombotic burden and treatment outcome of thrombocythemia and polycythemia patients.

World J Crit Care Med 2015 Aug 4;4(3):230-9. Epub 2015 Aug 4.

Jan Jacques Michiels, International Collaborations and Research on Myeloproliferative Neoplasms (ICAR.MPN) and Goodheart Institute and Foundation in Nature Medicine and Health, 3069 AT Rotterdam, The Netherlands.

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http://dx.doi.org/10.5492/wjccm.v4.i3.230DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524819PMC
August 2015

Membrane depolarization-triggered responsive diversification leads to antibiotic tolerance.

Microb Cell 2015 Jul 24;2(8):299-301. Epub 2015 Jul 24.

Centre of Microbial and Plant Genetics, KU Leuven - University of Leuven, 3001 Leuven, Belgium.

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http://dx.doi.org/10.15698/mic2015.08.220DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5349102PMC
July 2015

Fitness trade-offs explain low levels of persister cells in the opportunistic pathogen Pseudomonas aeruginosa.

Mol Ecol 2015 Apr 17;24(7):1572-83. Epub 2015 Mar 17.

Centre of Microbial and Plant Genetics, KU Leuven - University of Leuven, Kasteelpark Arenberg 20 bus 2460, 3001 Leuven, Belgium.

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http://dx.doi.org/10.1111/mec.13127DOI Listing
April 2015

Essential differences in clinical and bone marrow features in BCR/ABL-positive thrombocythemia compared to thrombocythemia in the BCR/ABL-negative myeloproliferative neoplasms essential thrombocythemia and polycythemia vera.

Acta Haematol 2015 7;133(1):52-5. Epub 2014 Aug 7.

Goodheart Institute and Foundation, European Working Group on Myeloproliferative Neoplasms, Rotterdam, The Netherlands.

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http://dx.doi.org/10.1159/000358915DOI Listing
February 2015

Novel anti-infective implant substrates: controlled release of antibiofilm compounds from mesoporous silica-containing macroporous titanium.

Colloids Surf B Biointerfaces 2015 Feb 7;126:481-8. Epub 2015 Jan 7.

Centre of Microbial and Plant Genetics (CMPG), KU Leuven, Kasteelpark Arenberg 20 Box 2460, 3001 Leuven, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.colsurfb.2014.12.054DOI Listing
February 2015

Diagnosis of deep vein thrombosis, and prevention of deep vein thrombosis recurrence and the post-thrombotic syndrome in the primary care medicine setting anno 2014.

World J Crit Care Med 2015 Feb 4;4(1):29-39. Epub 2015 Feb 4.

Jan Jacques Michiels, Wim Moossdorff, Mildred Lao, Hanny Maasland, Primary Care Medicine Medical Diagnostic Center, Vlambloem 21, 3068 JE Rotterdam, The Netherlands.

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http://dx.doi.org/10.5492/wjccm.v4.i1.29DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4326761PMC
February 2015

Population structure of root nodulating Rhizobium leguminosarum in Vicia cracca populations at local to regional geographic scales.

Syst Appl Microbiol 2014 Dec 22;37(8):613-21. Epub 2014 Aug 22.

Plant Conservation and Population Biology, Biology Department, KU Leuven, Kasteelpark Arenberg 31, B-3001 Leuven, Belgium.

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http://dx.doi.org/10.1016/j.syapm.2014.08.002DOI Listing
December 2014

The fungal aroma gene ATF1 promotes dispersal of yeast cells through insect vectors.

Cell Rep 2014 Oct 9;9(2):425-32. Epub 2014 Oct 9.

Laboratory for Genetics and Genomics, Centre of Microbial and Plant Genetics (CMPG), Department of Microbial and Molecular Systems, KU Leuven, Gaston Geenslaan 1, 3001 Leuven (Heverlee), Belgium; VIB Laboratory of Systems Biology, Gaston Geenslaan 1, 3001 Leuven (Heverlee), Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2014.09.009DOI Listing
October 2014

Bacterial Obg proteins: GTPases at the nexus of protein and DNA synthesis.

Crit Rev Microbiol 2014 Aug 28;40(3):207-24. Epub 2013 Mar 28.

Centre of Microbial and Plant Genetics, KU Leuven - University of Leuven , Kasteelpark Arenberg 20, 3001 Heverlee , Kasteelpark Arenberg 20, 3001 Heverlee and.

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http://dx.doi.org/10.3109/1040841X.2013.776510DOI Listing
August 2014

Comparison of Von Willebrand factor (VWF) activity VWF:Ac with VWF ristocetin cofactor activity VWF:RCo.

Thromb Res 2014 Aug 17;134(2):246-50. Epub 2014 May 17.

Department of Cardiovascular Surgery, Heart Center University of Freiburg, Freiburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.thromres.2014.04.033DOI Listing
August 2014

Excited state dynamics of the photoconvertible fluorescent protein Kaede revealed by ultrafast spectroscopy.

Photochem Photobiol Sci 2014 Jun;13(6):867-74

Laboratory of Photochemistry and Spectroscopy, Department of Chemistry, KU Leuven, Celestijnenlaan 200F, 3001 Heverlee, Belgium.

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http://dx.doi.org/10.1039/c3pp50335fDOI Listing
June 2014

Genomic analysis of cyclic-di-GMP-related genes in rhizobial type strains and functional analysis in Rhizobium etli.

Appl Microbiol Biotechnol 2014 May 12;98(10):4589-602. Epub 2014 Apr 12.

Centre of Microbial and Plant Genetics, KU Leuven, Kasteelpark Arenberg 20, P.O. Box 2460, 3001, Heverlee, Belgium.

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http://dx.doi.org/10.1007/s00253-014-5722-7DOI Listing
May 2014

COLOMBOS v2.0: an ever expanding collection of bacterial expression compendia.

Nucleic Acids Res 2014 Jan 8;42(Database issue):D649-53. Epub 2013 Nov 8.

Department of Mathematics and Computer Science, University of Antwerp, B-2020 Antwerp, Belgium, Biomedical Informatics Research Center Antwerp (biomina), University of Antwerp/Antwerp University Hospital, B-2650 Edegem, Belgium, Department of Computational Biology, Research and Innovation Center, Fondazione Edmund Mach, San Michele all'Adige, Trento (TN) 38010, Italy, Department of Microbial and Molecular Sciences, KU Leuven, Leuven B-3001, Belgium, Centro de Ciencias Genómicas, Universidad Nacional Autónoma de México, Cuernavaca, Morelos 62210, Mexico, Department of Plant Biotechnology and Bioinformatics, Ghent University, Gent 9052, Belgium and Department of Information Technology, IMinds, Ghent University, Gent 9052, Belgium.

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http://dx.doi.org/10.1093/nar/gkt1086DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3965013PMC
January 2014

Canonical and non-canonical EcfG sigma factors control the general stress response in Rhizobium etli.

Microbiologyopen 2013 Dec 28;2(6):976-87. Epub 2013 Oct 28.

Centre of Microbial and Plant Genetics, KU Leuven, Heverlee, B-3001, Belgium.

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http://dx.doi.org/10.1002/mbo3.137DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3892343PMC
December 2013

Revealing the excited-state dynamics of the fluorescent protein Dendra2.

J Phys Chem B 2013 Feb 15;117(8):2300-13. Epub 2013 Feb 15.

Division of Molecular Imaging and Photonics, Department of Chemistry, Katholieke Universiteit Leuven, Celestijnenlaan 200F, 3001 Heverlee, Belgium.

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http://dx.doi.org/10.1021/jp309219mDOI Listing
February 2013

New-found fundamentals of bacterial persistence.

Trends Microbiol 2012 Dec 5;20(12):577-85. Epub 2012 Sep 5.

Centre of Microbial and Plant Genetics, KU Leuven - University of Leuven, Kasteelpark Arenberg 20, 3001 Heverlee, Belgium.

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http://dx.doi.org/10.1016/j.tim.2012.08.009DOI Listing
December 2012

Functional divergence of gene duplicates through ectopic recombination.

EMBO Rep 2012 Dec 16;13(12):1145-51. Epub 2012 Oct 16.

Department of Microbial and Molecular Systems, Centre of Microbial and Plant Genetics (CMPG), KU Leuven, Kasteelpark Arenberg 22, B-3001 Leuven (Heverlee), Belgium.

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http://dx.doi.org/10.1038/embor.2012.157DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3512402PMC
December 2012

The Escherichia coli GTPase ObgE modulates hydroxyl radical levels in response to DNA replication fork arrest.

FEBS J 2012 Oct 31;279(19):3692-3704. Epub 2012 Aug 31.

 Centre of Microbial and Plant Genetics, Katholieke Universiteit Leuven, Heverlee, Belgium Department of Chemistry, Katholieke Universiteit Leuven, Heverlee, Belgium Structural Biology Brussels, Vrije Universiteit Brussel, Belgium Department of Structural Biology, Vlaams Instituut voor Biotechnologie, Brussels, Belgium.

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http://dx.doi.org/10.1111/j.1742-4658.2012.08731.xDOI Listing
October 2012

Stress response regulators identified through genome-wide transcriptome analysis of the (p)ppGpp-dependent response in Rhizobium etli.

Genome Biol 2011 16;12(2):R17. Epub 2011 Feb 16.

Centre of Microbial and Plant Genetics, Katholiek Universiteit Leuven, Kasteelpark Arenberg 20, 3001 Heverlee, Belgium.

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http://dx.doi.org/10.1186/gb-2011-12-2-r17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3188799PMC
February 2012

Spectroscopic characterization of Venus at the single molecule level.

Photochem Photobiol Sci 2012 Feb 3;11(2):358-63. Epub 2012 Jan 3.

Department of Chemistry, Katholieke Universiteit Leuven, Celestijnenlaan 200F, 3001, Heverlee, Belgium.

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http://dx.doi.org/10.1039/c1pp05292fDOI Listing
February 2012

Rational design of photoconvertible and biphotochromic fluorescent proteins for advanced microscopy applications.

Chem Biol 2011 Oct;18(10):1241-51

Laboratory of Photochemistry and Spectroscopy, Department of Chemistry, Katholieke Universiteit Leuven, 3001 Heverlee, Belgium.

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http://dx.doi.org/10.1016/j.chembiol.2011.08.007DOI Listing
October 2011

The universally conserved prokaryotic GTPases.

Microbiol Mol Biol Rev 2011 Sep;75(3):507-42, second and third pages of table of contents

Centre of Microbial and Plant Genetics, K. U. Leuven, Kasteelpark Arenberg 20, 3001 Leuven, Belgium.

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http://dx.doi.org/10.1128/MMBR.00009-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3165542PMC
September 2011

Role of persister cells in chronic infections: clinical relevance and perspectives on anti-persister therapies.

J Med Microbiol 2011 Jun 1;60(Pt 6):699-709. Epub 2011 Apr 1.

Centre of Microbial and Plant Genetics, K.U.Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1099/jmm.0.030932-0DOI Listing
June 2011

Genome sequence of Rhizobium etli CNPAF512, a nitrogen-fixing symbiont isolated from bean root nodules in Brazil.

J Bacteriol 2011 Jun 22;193(12):3158-9. Epub 2011 Apr 22.

Centre of Microbial and Plant Genetics, Kasteelpark Arenberg 20 bus 2460, BE-3001 Heverlee, Belgium.

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http://dx.doi.org/10.1128/JB.00310-11DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3133211PMC
June 2011

Pseudomonas aeruginosa fosfomycin resistance mechanisms affect non-inherited fluoroquinolone tolerance.

J Med Microbiol 2011 Mar 6;60(Pt 3):329-36. Epub 2011 Jan 6.

Centre of Microbial and Plant Genetics, KU Leuven, Leuven, Belgium.

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http://dx.doi.org/10.1099/jmm.0.019703-0DOI Listing
March 2011