Publications by authors named "Jan Matthes"

49Publications

A New Homozygous CACNB2 Mutation has Functional Relevance and Supports a Role for Calcium Channels in Autism Spectrum Disorder.

J Autism Dev Disord 2020 Jun 6. Epub 2020 Jun 6.

Unit of Medical Genetics, S. Orsola-Malpighi Hospital, Via Massarenti 9, 40138, Bologna, Italy.

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http://dx.doi.org/10.1007/s10803-020-04551-yDOI Listing
June 2020

Inhibition of EIF-5A prevents apoptosis in human cardiomyocytes after malaria infection.

Amino Acids 2020 May 4;52(5):693-710. Epub 2020 May 4.

Astel Diagnostics, Kampala, Uganda.

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http://dx.doi.org/10.1007/s00726-020-02843-2DOI Listing
May 2020

Autism-associated mutations in the Caβ calcium-channel subunit increase Ba-currents and lead to differential modulation by the RGK-protein Gem.

Neurobiol Dis 2020 03 27;136:104721. Epub 2019 Dec 27.

Centre of Pharmacology, University of Cologne, Cologne, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.nbd.2019.104721DOI Listing
March 2020

Direct, gabapentin-insensitive interaction of a soluble form of the calcium channel subunit αδ-1 with thrombospondin-4.

Sci Rep 2019 11 7;9(1):16272. Epub 2019 Nov 7.

Institute II for Pharmacology, Centre of Pharmacology, Medical Faculty, University of Cologne, Gleueler Str. 24, D-50931, Cologne, Germany.

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http://dx.doi.org/10.1038/s41598-019-52655-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6838084PMC
November 2019

Single-Channel Resolution of the Interaction between C-Terminal Ca1.3 Isoforms and Calmodulin.

Biophys J 2019 03 1;116(5):836-846. Epub 2019 Feb 1.

Center of Pharmacology, University of Cologne, Cologne, Germany; Cologne University of Applied Sciences, Cologne, Germany.

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http://dx.doi.org/10.1016/j.bpj.2019.01.025DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6403076PMC
March 2019

Development of perceived pharmacological deficits of medical students and alumni supports claim for continuous and more application-oriented education.

Naunyn Schmiedebergs Arch Pharmacol 2019 01 7;392(1):29-36. Epub 2018 Sep 7.

Center of Pharmacology, University of Cologne, Gleueler Strasse 24, 50931, Cologne, Germany.

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http://dx.doi.org/10.1007/s00210-018-1563-8DOI Listing
January 2019

Renal Metabolic Programming Is Linked to the Dynamic Regulation of a Leptin-Klf15 Axis and Akt/AMPKα Signaling in Male Offspring of Obese Dams.

Endocrinology 2017 10;158(10):3399-3415

Translational Experimental Pediatrics, University Hospital for Pediatrics and Adolescent Medicine, Faculty of Medicine, University of Cologne, 50937 Cologne, Germany.

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http://dx.doi.org/10.1210/en.2017-00489DOI Listing
October 2017

Publication activity in medical education research: A descriptive analysis of submissions to the GMS Zeitschrift für Medizinische Ausbildung in 2007-2015.

GMS J Med Educ 2017 15;34(3):Doc32. Epub 2017 Aug 15.

University Medicine Mannheim, Medical Faculty Mannheim at Heidelberg University, Department of Undergraduate Education and Educational Development, Mannheim, Germany.

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http://dx.doi.org/10.3205/zma001109DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5569980PMC
October 2018

Beta-adrenergic regulation of the heart expressing the Ser1700A/Thr1704A mutated Cav1.2 channel.

J Mol Cell Cardiol 2017 10 1;111:10-16. Epub 2017 Aug 1.

Institut für Pharmakologie und Toxikologie, Technische Universität München, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2017.07.119DOI Listing
October 2017

A multi-centre student survey on weighing disciplines in medical curricula - a pilot study.

GMS J Med Educ 2017 15;34(2):Doc24. Epub 2017 May 15.

University of Cologne, Centre of Pharmacology, Cologne, Germany.

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http://dx.doi.org/10.3205/zma001101DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450425PMC
May 2018

The prescription talk - an approach to teach patient-physician conversation about drug prescription to medical students.

GMS J Med Educ 2017 15;34(2):Doc18. Epub 2017 May 15.

Universität zu Köln, Zentrum für Pharmakologie, Institut II, Köln, Deutschland.

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http://dx.doi.org/10.3205/zma001095DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5450434PMC
May 2018

Medical students' medication communication skills regarding drug prescription-a qualitative analysis of simulated physician-patient consultations.

Eur J Clin Pharmacol 2017 Apr 14;73(4):429-435. Epub 2017 Jan 14.

Department of Pharmacology II, University of Cologne, Gleueler Strasse 24, 50931, Köln (Cologne), Germany.

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http://dx.doi.org/10.1007/s00228-016-2192-0DOI Listing
April 2017

An expert protocol for immunofluorescent detection of calcium channels in tsA-201 cells.

J Pharmacol Toxicol Methods 2016 Nov - Dec;82:20-25. Epub 2016 Jul 12.

Department of Pharmacology, University Clinic Cologne, Gleuelerstrasse 24, D-50931 Cologne, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.vascn.2016.07.001DOI Listing
May 2017

Peyton's 4-Steps-Approach in comparison: Medium-term effects on learning external chest compression - a pilot study.

GMS J Med Educ 2016 15;33(4):Doc60. Epub 2016 Aug 15.

University of Cologne, Department of Pharmacology, Cologne, Germany.

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http://dx.doi.org/10.3205/zma001059DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5003127PMC
March 2018

In Reply.

Authors:
Jan Matthes
April 2016

A study on effects of and stance over tuition fees.

GMS J Med Educ 2016 15;33(1):Doc6. Epub 2016 Feb 15.

University of Cologne, Department of Pharmacology, Cologne, Germany.

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http://dx.doi.org/10.3205/zma001005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4766930PMC
April 2017

Outcome-Relevant Effects of Shared Decision Making.

Dtsch Arztebl Int 2015 Oct;112(40):665-71

Department of Pharmacology, University of Cologne, Department of Psychosomatics and Psychotherapy, University Hospital of Cologne, Institute of Medical Statistics, Informatics and Epidemiology, University of Cologne.

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http://dx.doi.org/10.3238/arztebl.2015.0665DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4640070PMC
October 2015

Voltage-gated Calcium Channels and Autism Spectrum Disorders.

Curr Mol Pharmacol 2015 ;8(2):123-32

Department of Pharmacology, University of Cologne, Cologne, Germany.

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http://dx.doi.org/10.2174/1874467208666150507105235DOI Listing
July 2016

Lucky guess or knowledge: a cross-sectional study using the Bland and Altman analysis to compare confidence-based testing of pharmacological knowledge in 3rd and 5th year medical students.

Adv Health Sci Educ Theory Pract 2015 May 8;20(2):431-40. Epub 2014 Aug 8.

Department of Pharmacology, University of Cologne, Priv.-Doz. Dr. med. Jan Matthes, Gleueler Strasse 24, 50931, Cologne, Germany,

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http://dx.doi.org/10.1007/s10459-014-9537-1DOI Listing
May 2015

Spectrum of Cav1.4 dysfunction in congenital stationary night blindness type 2.

Biochim Biophys Acta 2014 Aug 4;1838(8):2053-65. Epub 2014 May 4.

Medical University Vienna, Center for Physiology and Pharmacology, Department of Neurophysiology and -pharmacology, Schwarzspanierstrasse 17, 1090 Vienna, Austria. Electronic address:

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http://dx.doi.org/10.1016/j.bbamem.2014.04.023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4065569PMC
August 2014

Rare mutations of CACNB2 found in autism spectrum disease-affected families alter calcium channel function.

PLoS One 2014 21;9(4):e95579. Epub 2014 Apr 21.

Department of Pharmacology, University of Cologne, Cologne, Germany; Center for Molecular Medicine, University of Cologne, Cologne, Germany.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0095579PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3994086PMC
January 2015

Improving adherence with medication: a selective literature review based on the example of hypertension treatment.

Dtsch Arztebl Int 2014 Jan;111(4):41-7

Department of Pharmacology, University of Cologne, Department of Psychosomatics and Psychotherapy, University Hospital of Cologne.

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http://dx.doi.org/10.3238/arztebl.2014.0041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3950822PMC
January 2014

Effect of MANT-nucleotides on L-type calcium currents in murine cardiomyocytes.

Naunyn Schmiedebergs Arch Pharmacol 2011 Jun 12;383(6):573-83. Epub 2011 Apr 12.

Department of Pharmacology and Toxicology, University of Regensburg, Regensburg, Germany.

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http://link.springer.com/content/pdf/10.1007/s00210-011-0626
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http://link.springer.com/10.1007/s00210-011-0626-x
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http://dx.doi.org/10.1007/s00210-011-0626-xDOI Listing
June 2011

Recommendations for reviewing a manuscript for the GMS Zeitschrift für Medizinische Ausbildung.

GMS Z Med Ausbild 2010 15;27(5):Doc75. Epub 2010 Nov 15.

Charité-Universitätsmedizin Berlin, Dieter Scheffner Fachzentrum, Assessment-Bereich/Progress Test Medizin, Berlin, Deutschland.

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http://dx.doi.org/10.3205/zma000712DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3140379PMC
September 2012

Less is more, or enough is enough? Ca(2+)-dependent inactivation revisited.

J Physiol 2010 Jan 30;588(Pt 1):15-6. Epub 2009 Nov 30.

Department of Pharmacology, University of Cologne.

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http://dx.doi.org/10.1113/jphysiol.2009.184846DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2821538PMC
January 2010

Inactivation of L-type calcium channels is determined by the length of the N terminus of mutant beta(1) subunits.

Pflugers Arch 2010 Feb 12;459(3):399-411. Epub 2009 Oct 12.

Department of Pharmacology, University of Cologne, Gleueler Strasse 24, 50931 Cologne, Germany.

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http://dx.doi.org/10.1007/s00424-009-0738-zDOI Listing
February 2010

The semi-structured triple jump--a new assessment tool reflects qualifications of tutors in a PBL course on basic pharmacology.

Naunyn Schmiedebergs Arch Pharmacol 2008 Mar 11;377(1):55-63. Epub 2008 Jan 11.

Department of Pharmacology, University of Cologne, Gleueler Strasse 24, 50931 Cologne (Köln), Germany.

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http://dx.doi.org/10.1007/s00210-007-0257-4DOI Listing
March 2008

Mechanism of Ca(v)1.2 channel modulation by the amino terminus of cardiac beta2-subunits.

FASEB J 2007 May 8;21(7):1527-38. Epub 2007 Feb 8.

Department of Pharmacology, University of Cologne, Gleueler Strasse 24, 50931 Köln, Germany.

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http://dx.doi.org/10.1096/fj.06-7377comDOI Listing
May 2007

Functional adenylyl cyclase inhibition in murine cardiomyocytes by 2'(3')-O-(N-methylanthraniloyl)-guanosine 5'-[gamma-thio]triphosphate.

J Pharmacol Exp Ther 2007 May 6;321(2):608-15. Epub 2007 Feb 6.

Department of Pharmacology, Center for Molecular Medicine, University of Cologne, Gleueler Str. 24, D-50931 Köln, Germany.

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http://dx.doi.org/10.1124/jpet.106.118422DOI Listing
May 2007

Mechanisms of [Ca2+]i transient decrease in cardiomyopathy of db/db type 2 diabetic mice.

Diabetes 2006 Mar;55(3):608-15

Institut National de la Santé et de la Recherche Médicale U-637, University of Montpellier 1, France.

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http://dx.doi.org/10.2337/diabetes.55.03.06.db05-1284DOI Listing
March 2006

An aqueous extract of the marine sponge Ectyoplasia ferox stimulates L-type Ca2+-current by direct interaction with the Cav1.2 subunit.

Naunyn Schmiedebergs Arch Pharmacol 2004 Dec 18;370(6):474-83. Epub 2004 Nov 18.

Department of Pharmacology and Toxicology, Dresden University of Technology, Fetscherstrasse 74, 01309 Dresden, Germany.

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http://dx.doi.org/10.1007/s00210-004-0996-4DOI Listing
December 2004

Disturbed atrio-ventricular conduction and normal contractile function in isolated hearts from Cav1.3-knockout mice.

Naunyn Schmiedebergs Arch Pharmacol 2004 Jun 14;369(6):554-62. Epub 2004 May 14.

Department of Pharmacology, University of Cologne, Gleueler Strasse 24, 50931 Cologne, Germany.

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http://link.springer.com/10.1007/s00210-004-0940-7
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http://dx.doi.org/10.1007/s00210-004-0940-7DOI Listing
June 2004

Calcium channel function and regulation in beta 1- and beta 2-adrenoceptor transgenic mice.

Naunyn Schmiedebergs Arch Pharmacol 2004 May 9;369(5):490-5. Epub 2004 Apr 9.

Department of Pharmacology, University of Cologne, Gleueler Strasse 24, 50931 Cologne, Germany.

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http://link.springer.com/10.1007/s00210-004-0928-3
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http://dx.doi.org/10.1007/s00210-004-0928-3DOI Listing
May 2004

Ca2+-dependent modulation of single human cardiac L-type calcium channels by the calcineurin inhibitor cyclosporine.

J Mol Cell Cardiol 2004 Feb;36(2):241-55

Department of Pharmacology, University of Cologne, Gleueler Strasse 24, Cologne 50931, Germany.

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http://dx.doi.org/10.1016/j.yjmcc.2003.11.013DOI Listing
February 2004

Single-channel gating and regulation of human L-type calcium channels in cardiomyocytes of transgenic mice.

Biochem Biophys Res Commun 2004 Feb;314(3):878-84

Department of Pharmacology, University of Cologne, 50931, Köln, Germany.

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http://dx.doi.org/10.1016/j.bbrc.2003.12.174DOI Listing
February 2004

Cardioprotection specific for the G protein Gi2 in chronic adrenergic signaling through beta 2-adrenoceptors.

Proc Natl Acad Sci U S A 2003 Nov 11;100(24):14475-80. Epub 2003 Nov 11.

Department of Pharmacology, University of Cologne, Gleueler Strasse 24, 50931 Cologne, Germany.

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http://www.pnas.org/cgi/doi/10.1073/pnas.1936026100
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http://dx.doi.org/10.1073/pnas.1936026100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC283616PMC
November 2003

The influence of tutor qualification on the process and outcome of learning in a problem-based course of basic medical pharmacology.

Naunyn Schmiedebergs Arch Pharmacol 2002 Jul 19;366(1):58-63. Epub 2002 Apr 19.

Department of Pharmacology, University of Cologne, Gleueler Strasse 24, 50931 Köln, Germany.

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http://link.springer.com/10.1007/s00210-002-0551-0
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http://dx.doi.org/10.1007/s00210-002-0551-0DOI Listing
July 2002