Jan J De Waele

Jan J De Waele

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Jan J De Waele

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Early target attainment of continuous infusion piperacillin/tazobactam and meropenem in critically ill patients: A prospective observational study.

J Crit Care 2019 Aug 9;52:75-79. Epub 2019 Apr 9.

Department of Intensive Care Medicine, Ghent University Hospital, Ghent, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.jcrc.2019.04.013DOI Listing
August 2019

Subtherapeutic piperacillin concentrations in neurocritical patients.

J Crit Care 2019 Jul 10;54:48-51. Epub 2019 Jul 10.

Department of Critical Care Medicine, Ghent University Hospital, Corneel Heymanslaan 10, 9000 Gent, Belgium.

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http://dx.doi.org/10.1016/j.jcrc.2019.07.007DOI Listing
July 2019

Optimal and responsible use of antibiotics.

Curr Opin Crit Care 2019 Jul 31. Epub 2019 Jul 31.

Department of Critical Care Medicine, Ghent University Hospital, Ghent, Belgium.

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http://dx.doi.org/10.1097/MCC.0000000000000645DOI Listing
July 2019

Measuring Unbound Versus Total Piperacillin Concentrations in Plasma of Critically Ill Patients: Methodological Issues and Relevance.

Ther Drug Monit 2019 06;41(3):325-330

Department of Laboratory Medicine, Ghent University Hospital, Ghent, Belgium.

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http://dx.doi.org/10.1097/FTD.0000000000000602DOI Listing
June 2019

ESICM/ESCMID task force on practical management of invasive candidiasis in critically ill patients.

Intensive Care Med 2019 Jun 25;45(6):789-805. Epub 2019 Mar 25.

Infectious Diseases Clinic, Department of Medicine University of Udine and Azienda Sanitaria Universitaria Integrata di Udine, Udine, Italy.

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http://dx.doi.org/10.1007/s00134-019-05599-wDOI Listing
June 2019

Personalized antibiotic dosing for the critically ill.

Intensive Care Med 2019 May 14;45(5):715-718. Epub 2019 Jan 14.

Department of Critical Care Medicine, Ghent University Hospital, Ghent, Belgium.

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http://dx.doi.org/10.1007/s00134-019-05522-3DOI Listing
May 2019

Antibiotic stewardship in sepsis management: toward a balanced use of antibiotics for the severely ill patient.

Expert Rev Anti Infect Ther 2019 02 23;17(2):89-97. Epub 2019 Jan 23.

a Department of Critical Care Medicine , Ghent University Hospital , Gent , Belgium.

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http://dx.doi.org/10.1080/14787210.2019.1568239DOI Listing
February 2019

Optimal duration of antibiotic treatment in Gram-negative infections.

Curr Opin Infect Dis 2018 12;31(6):606-611

Multidisciplinary Intensive Care Research Organization (MICRO), Department of Intensive Care Medicine, St James's Hospital, Dublin, Ireland.

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http://dx.doi.org/10.1097/QCO.0000000000000491DOI Listing
December 2018

Emergence of antimicrobial resistance to piperacillin/tazobactam or meropenem in the ICU: Intermittent versus continuous infusion. A retrospective cohort study.

J Crit Care 2018 10 4;47:164-168. Epub 2018 Jul 4.

Faculty of Medicine and Health Sciences, Ghent University, Ghent, Belgium; Department of Intensive Care Medicine, Ghent University Hospital, Ghent, Belgium. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S08839441183019
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http://dx.doi.org/10.1016/j.jcrc.2018.07.003DOI Listing
October 2018

The defining a model for antimicrobial stewardship-results from an international cross-sectional survey.

Authors:
Massimo Sartelli Francesco M Labricciosa Pamela Barbadoro Leonardo Pagani Luca Ansaloni Adrian J Brink Jean Carlet Ashish Khanna Alain Chichom-Mefire Federico Coccolini Salomone Di Saverio Addison K May Pierluigi Viale Richard R Watkins Luigia Scudeller Lilian M Abbo Fikri M Abu-Zidan Abdulrashid K Adesunkanmi Sara Al-Dahir Majdi N Al-Hasan Halil Alis Carlos Alves André R Araujo da Silva Goran Augustin Miklosh Bala Philip S Barie Marcelo A Beltrán Aneel Bhangu Belefquih Bouchra Stephen M Brecher Miguel A Caínzos Adrian Camacho-Ortiz Marco Catani Sujith J Chandy Asri Che Jusoh Jill R Cherry-Bukowiec Osvaldo Chiara Elif Colak Oliver A Cornely Yunfeng Cui Zaza Demetrashvili Belinda De Simone Jan J De Waele Sameer Dhingra Francesco Di Marzo Agron Dogjani Gereltuya Dorj Laurent Dortet Therese M Duane Mutasim M Elmangory Mushira A Enani Paula Ferrada J Esteban Foianini Mahir Gachabayov Chinmay Gandhi Wagih Mommtaz Ghnnam Helen Giamarellou Georgios Gkiokas Harumi Gomi Tatjana Goranovic Ewen A Griffiths Rosio I Guerra Gronerth Julio C Haidamus Monteiro Timothy C Hardcastle Andreas Hecker Adrien M Hodonou Orestis Ioannidis Arda Isik Katia A Iskandar Hossein S Kafil Souha S Kanj Lewis J Kaplan Garima Kapoor Aleksandar R Karamarkovic Jakub Kenig Ivan Kerschaever Faryal Khamis Vladimir Khokha Ronald Kiguba Hong B Kim Wen-Chien Ko Kaoru Koike Iryna Kozlovska Anand Kumar Leonel Lagunes Rifat Latifi Jae G Lee Young R Lee Ari Leppäniemi Yousheng Li Stephen Y Liang Warren Lowman Gustavo M Machain Marc Maegele Piotr Major Sydney Malama Ramiro Manzano-Nunez Athanasios Marinis Isidro Martinez Casas Sanjay Marwah Emilio Maseda Michael E McFarlane Ziad Memish Dominik Mertz Cristian Mesina Shyam K Mishra Ernest E Moore Akutu Munyika Eleftherios Mylonakis Lena Napolitano Ionut Negoi Milica D Nestorovic David P Nicolau Abdelkarim H Omari Carlos A Ordonez José-Artur Paiva Narayan D Pant Jose G Parreira Michal Pędziwiatr Bruno M Pereira Alfredo Ponce-de-Leon Garyphallia Poulakou Jacobus Preller Céline Pulcini Guntars Pupelis Martha Quiodettis Timothy M Rawson Tarcisio Reis Miran Rems Sandro Rizoli Jason Roberts Nuno Rocha Pereira Jesús Rodríguez-Baño Boris Sakakushev James Sanders Natalia Santos Norio Sato Robert G Sawyer Sandro Scarpelini Loredana Scoccia Nusrat Shafiq Vishalkumar Shelat Costi D Sifri Boonying Siribumrungwong Kjetil Søreide Rodolfo Soto Hamilton P de Souza Peep Talving Ngo Tat Trung Jeffrey M Tessier Mario Tumbarello Jan Ulrych Selman Uranues Harry Van Goor Andras Vereczkei Florian Wagenlehner Yonghong Xiao Kuo-Ching Yuan Agnes Wechsler-Fördös Jean-Ralph Zahar Tanya L Zakrison Brian Zuckerbraun Wietse P Zuidema Fausto Catena

World J Emerg Surg 2017 1;12:34. Epub 2017 Aug 1.

Department of General Surgery, Maggiore Hospital, Parma, Italy.

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http://dx.doi.org/10.1186/s13017-017-0145-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5540347PMC
September 2018

Effect of decompressive laparotomy on organ function in patients with abdominal compartment syndrome: a systematic review and meta-analysis.

Crit Care 2018 07 25;22(1):179. Epub 2018 Jul 25.

Department of Critical Care Medicine, Ghent University Hospital, C. Heymanslaan 10, 9000, Ghent, Belgium.

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http://dx.doi.org/10.1186/s13054-018-2103-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6060511PMC
July 2018

Update from the Abdominal Compartment Society (WSACS) on intra-abdominal hypertension and abdominal compartment syndrome: past, present, and future beyond Banff 2017.

Anaesthesiol Intensive Ther 2017 14;49(2):83-87. Epub 2017 May 14.

Department of Intensive Care and High Care Burn Unit, Ziekenhuis Netwerk Antwerpen, ZNA Stuivenberg, Antwerp, Belgium, and Department of Intensive Care, University Hospital Brussel (UZ Brussel), Jette, Belgium, The Free University of Brussels (VUB).

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http://dx.doi.org/10.5603/AIT.a2017.0019DOI Listing
June 2018

Antimicrobials: a global alliance for optimizing their rational use in intra-abdominal infections (AGORA).

Authors:
Massimo Sartelli Dieter G Weber Etienne Ruppé Matteo Bassetti Brian J Wright Luca Ansaloni Fausto Catena Federico Coccolini Fikri M Abu-Zidan Raul Coimbra Ernest E Moore Frederick A Moore Ronald V Maier Jan J De Waele Andrew W Kirkpatrick Ewen A Griffiths Christian Eckmann Adrian J Brink John E Mazuski Addison K May Rob G Sawyer Dominik Mertz Philippe Montravers Anand Kumar Jason A Roberts Jean-Louis Vincent Richard R Watkins Warren Lowman Brad Spellberg Iain J Abbott Abdulrashid Kayode Adesunkanmi Sara Al-Dahir Majdi N Al-Hasan Ferdinando Agresta Asma A Althani Shamshul Ansari Rashid Ansumana Goran Augustin Miklosh Bala Zsolt J Balogh Oussama Baraket Aneel Bhangu Marcelo A Beltrán Michael Bernhard Walter L Biffl Marja A Boermeester Stephen M Brecher Jill R Cherry-Bukowiec Otmar R Buyne Miguel A Cainzos Kelly A Cairns Adrian Camacho-Ortiz Sujith J Chandy Asri Che Jusoh Alain Chichom-Mefire Caroline Colijn Francesco Corcione Yunfeng Cui Daniel Curcio Samir Delibegovic Zaza Demetrashvili Belinda De Simone Sameer Dhingra José J Diaz Isidoro Di Carlo Angel Dillip Salomone Di Saverio Michael P Doyle Gereltuya Dorj Agron Dogjani Hervé Dupont Soumitra R Eachempati Mushira Abdulaziz Enani Valery N Egiev Mutasim M Elmangory Paula Ferrada Joseph R Fitchett Gustavo P Fraga Nathalie Guessennd Helen Giamarellou Wagih Ghnnam George Gkiokas Staphanie R Goldberg Carlos Augusto Gomes Harumi Gomi Manuel Guzmán-Blanco Mainul Haque Sonja Hansen Andreas Hecker Wolfgang R Heizmann Torsten Herzog Adrien Montcho Hodonou Suk-Kyung Hong Reinhold Kafka-Ritsch Lewis J Kaplan Garima Kapoor Aleksandar Karamarkovic Martin G Kees Jakub Kenig Ronald Kiguba Peter K Kim Yoram Kluger Vladimir Khokha Kaoru Koike Kenneth Y Y Kok Victory Kong Matthew C Knox Kenji Inaba Arda Isik Katia Iskandar Rao R Ivatury Maurizio Labbate Francesco M Labricciosa Pierre-François Laterre Rifat Latifi Jae Gil Lee Young Ran Lee Marc Leone Ari Leppaniemi Yousheng Li Stephen Y Liang Tonny Loho Marc Maegele Sydney Malama Hany E Marei Ignacio Martin-Loeches Sanjay Marwah Amos Massele Michael McFarlane Renato Bessa Melo Ionut Negoi David P Nicolau Carl Erik Nord Richard Ofori-Asenso AbdelKarim H Omari Carlos A Ordonez Mouaqit Ouadii Gerson Alves Pereira Júnior Diego Piazza Guntars Pupelis Timothy Miles Rawson Miran Rems Sandro Rizoli Claudio Rocha Boris Sakakushev Miguel Sanchez-Garcia Norio Sato Helmut A Segovia Lohse Gabriele Sganga Boonying Siribumrungwong Vishal G Shelat Kjetil Soreide Rodolfo Soto Peep Talving Jonathan V Tilsed Jean-Francois Timsit Gabriel Trueba Ngo Tat Trung Jan Ulrych Harry van Goor Andras Vereczkei Ravinder S Vohra Imtiaz Wani Waldemar Uhl Yonghong Xiao Kuo-Ching Yuan Sanoop K Zachariah Jean-Ralph Zahar Tanya L Zakrison Antonio Corcione Rita M Melotti Claudio Viscoli Perluigi Viale

World J Emerg Surg 2016 15;11:33. Epub 2016 Jul 15.

Infectious Diseases Unit, Department of Medical and Surgical Sciences, Sant' Orsola Hospital, University of Bologna, Bologna, Italy.

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http://dx.doi.org/10.1186/s13017-016-0089-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4946132PMC
May 2018

Population pharmacokinetics of continuous infusion of piperacillin in critically ill patients.

Int J Antimicrob Agents 2018 Apr 22;51(4):594-600. Epub 2017 Dec 22.

Ghent University Hospital, Intensive Care, Ghent, Belgium.

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http://dx.doi.org/10.1016/j.ijantimicag.2017.12.015DOI Listing
April 2018

What every intensivist should know about the management of peritonitis in the intensive care unit.

Authors:
Jan J De Waele

Rev Bras Ter Intensiva 2018 Mar;30(1):9-14

Department of Critical Care Medicine, Ghent University Hospital, Ghent, Belgium.

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http://dx.doi.org/10.5935/0103-507x.20180007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5885225PMC
March 2018

Awareness and knowledge of intra-abdominal hypertension and abdominal compartment syndrome: results of an international survey.

Anaesthesiol Intensive Ther 2015 24;47(1):14-29. Epub 2014 Sep 24.

ICU Department and High Care Burn Unit, Ziekenhuis Netwerk Antwerpen, ZNA Stuivenberg, Lange Beeldekensstraat 267, B-2060 Antwerpen, Belgium.

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http://dx.doi.org/10.5603/AIT.2014.0051DOI Listing
January 2018

Stability of amoxicillin and amoxicillin/clavulanic acid reconstituted in isotonic saline.

J Chemother 2017 Feb 22;29(1):54-56. Epub 2016 Jul 22.

a Department of Clinical Chemistry, Microbiology and Immunology , Ghent University , Ghent , Belgium.

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http://dx.doi.org/10.1179/1973947815Y.0000000052DOI Listing
February 2017

Abdominal Sepsis.

Authors:
Jan J De Waele

Curr Infect Dis Rep 2016 Aug;18(8):23

Department of Critical Care Medicine, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium.

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http://dx.doi.org/10.1007/s11908-016-0531-zDOI Listing
August 2016

How to deal with an open abdomen?

Anaesthesiol Intensive Ther 2015 14;47(4):372-8. Epub 2015 May 14.

Department of Critical Care Medicine, Ghent University Hospital, Ghent, Belgium.

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http://dx.doi.org/10.5603/AIT.a2015.0023DOI Listing
July 2016

Management of abdominal sepsis--a paradigm shift?

Anaesthesiol Intensive Ther 2015 14;47(4):400-8. Epub 2015 May 14.

Meilahti hospital, Abdominal Center, University of Helsinki, Finland.

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http://dx.doi.org/10.5603/AIT.a2015.0026DOI Listing
July 2016

What every ICU clinician needs to know about the cardiovascular effects caused by abdominal hypertension.

Anaesthesiol Intensive Ther 2015 14;47(4):388-99. Epub 2015 May 14.

Intensive Care Unit and High Care Burn Unit, Ziekenhuis Netwerk Antwerpen, ZNA Stuivenberg, Antwerp, Belgium.

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http://czasopisma.viamedica.pl/ait/article/view/41691
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http://dx.doi.org/10.5603/AIT.a2015.0028DOI Listing
July 2016

Intermittent axillary temperature measurement fails to detect fever in critically ill patients.

Minerva Anestesiol 2016 06 17;82(6):721-2. Epub 2016 Mar 17.

Department of Critical Care Medicine, Ghent University Hospital, Ghent, Belgium -

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June 2016

Impact of de-escalation of beta-lactam antibiotics on the emergence of antibiotic resistance in ICU patients: a retrospective observational study.

Intensive Care Med 2016 Jun 30;42(6):1029-39. Epub 2016 Mar 30.

Department of Critical Care Medicine, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium.

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http://dx.doi.org/10.1007/s00134-016-4301-zDOI Listing
June 2016

Intra-abdominal hypertension and abdominal compartment syndrome in burns, obesity, pregnancy, and general medicine.

Anaesthesiol Intensive Ther 2015 14;47(3):228-40. Epub 2015 May 14.

Intensive Care Unit and High Care Burn Unit, Ziekenhuis Netwerk Antwerpen, ZNA Stuivenberg, Antwerp, Belgium.

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http://www.aacn.org/wd/Cetests/media/C1212.pdf
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http://czasopisma.viamedica.pl/ait/article/view/41680
Publisher Site
http://dx.doi.org/10.5603/AIT.a2015.0021DOI Listing
April 2016

Intra-abdominal hypertension and abdominal compartment syndrome in pancreatitis, paediatrics, and trauma.

Anaesthesiol Intensive Ther 2015 14;47(3):219-27. Epub 2015 May 14.

Department of Intensive Care and High Care Burn Unit, Ziekenhuis Netwerk Antwerpen, Belgium.

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http://dx.doi.org/10.5603/AIT.a2015.0027DOI Listing
April 2016

A user's guide to intra-abdominal pressure measurement.

Anaesthesiol Intensive Ther 2015 14;47(3):241-51. Epub 2015 May 14.

Department of Intensive Care and High Care Burn Unit, Ziekenhuis Netwerk Antwerpen, Belgium.

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http://dx.doi.org/10.5603/AIT.a2015.0025DOI Listing
April 2016

Assays for therapeutic drug monitoring of β-lactam antibiotics: A structured review.

Int J Antimicrob Agents 2015 Oct 29;46(4):367-75. Epub 2015 Jul 29.

Burns, Trauma and Critical Care Research Centre, University of Queensland, Brisbane, Queensland, Australia; Department of Intensive Care Medicine, Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia; Institute of Translational Medicine, University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.1016/j.ijantimicag.2015.06.016DOI Listing
October 2015

A Simulation Study Reveals Lack of Pharmacokinetic/Pharmacodynamic Target Attainment in De-escalated Antibiotic Therapy in Critically Ill Patients.

Antimicrob Agents Chemother 2015 Aug 26;59(8):4689-94. Epub 2015 May 26.

Department of Critical Care Medicine, Ghent University Hospital, Ghent, Belgium.

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http://dx.doi.org/10.1128/AAC.00409-15DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4505256PMC
August 2015

Subtleties in practical application of prolonged infusion of β-lactam antibiotics.

Int J Antimicrob Agents 2015 May 16;45(5):461-3. Epub 2015 Feb 16.

Burns, Trauma and Critical Care Research Centre, The University of Queensland, Brisbane, Queensland, Australia; Royal Brisbane and Women's Hospital, Brisbane, Queensland, Australia; Institute of Translational Medicine, University of Liverpool, Liverpool, UK.

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http://dx.doi.org/10.1016/j.ijantimicag.2015.01.007DOI Listing
May 2015

Erratum to: Risk factors for target non-attainment during empirical treatment with β-lactam antibiotics in critically ill patients.

Intensive Care Med 2015 May;41(5):969

Department of Critical Care Medicine, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium,

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http://dx.doi.org/10.1007/s00134-015-3772-7DOI Listing
May 2015

Measuring unbound versus total vancomycin concentrations in serum and plasma: methodological issues and relevance.

Ther Drug Monit 2015 Apr;37(2):180-7

*Department of Laboratory Medicine, Ghent University Hospital; †Department of Clinical Chemistry, Microbiology and Immunology, Ghent University; and ‡Department of Critical Care Medicine, Ghent University Hospital, Belgium.

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http://dx.doi.org/10.1097/FTD.0000000000000122DOI Listing
April 2015

Augmented renal clearance and therapeutic monitoring of β-lactams.

Int J Antimicrob Agents 2015 Apr 20;45(4):331-3. Epub 2015 Jan 20.

Department of Intensive Care Medicine, Royal Brisbane and Women's Hospital, Herston, Brisbane 4029, QLD, Australia; Burns, Trauma, and Critical Care Research Centre, The University of Queensland, Herston, Brisbane 4029, QLD, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.ijantimicag.2014.12.020DOI Listing
April 2015

Ultrafast quantification of β-lactam antibiotics in human plasma using UPLC-MS/MS.

J Chromatogr B Analyt Technol Biomed Life Sci 2015 Jan 8;978-979:89-94. Epub 2014 Dec 8.

Department of Clinical Chemistry, Microbiology and Immunology, Ghent University, De Pintelaan 185, Building 2P8, 9000 Ghent, Belgium; Department of Laboratory Medicine, Ghent University Hospital, De Pintelaan 185, Building 2P8, 9000 Ghent, Belgium.

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http://dx.doi.org/10.1016/j.jchromb.2014.11.034DOI Listing
January 2015

Population pharmacokinetics and dosing simulations of cefuroxime in critically ill patients: non-standard dosing approaches are required to achieve therapeutic exposures.

J Antimicrob Chemother 2014 Oct 10;69(10):2797-803. Epub 2014 Jun 10.

Department of Critical Care Medicine, Ghent University Hospital, Ghent, Belgium.

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http://dx.doi.org/10.1093/jac/dku195DOI Listing
October 2014

Impact of de-escalation on ICU patients' prognosis.

Intensive Care Med 2014 Oct 13;40(10):1583-5. Epub 2014 Sep 13.

Department of Critical Care Medicine, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium,

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http://dx.doi.org/10.1007/s00134-014-3488-0DOI Listing
October 2014

Reply to Rhodes et al.

Clin Infect Dis 2014 Sep 27;59(6):907-8. Epub 2014 May 27.

Burns Trauma and Critical Care Research Centre, University of Queensland Royal Brisbane and Women's Hospital, Australia.

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http://dx.doi.org/10.1093/cid/ciu403DOI Listing
September 2014

Risk factors for target non-attainment during empirical treatment with β-lactam antibiotics in critically ill patients.

Intensive Care Med 2014 Sep 23;40(9):1340-51. Epub 2014 Jul 23.

Department of Critical Care Medicine, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium,

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http://dx.doi.org/10.1007/s00134-014-3403-8DOI Listing
September 2014

Severe lactic acidosis in critically ill patients with acute kidney injury treated with renal replacement therapy.

J Crit Care 2014 Aug 5;29(4):650-5. Epub 2014 Mar 5.

Department of Intensive Care Medicine, Ghent University Hospital, Ghent, Belgium; Research Foundation Flanders, Belgium.

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http://dx.doi.org/10.1016/j.jcrc.2014.02.019DOI Listing
August 2014

Infections and use of antibiotics in patients admitted for severe acute pancreatitis: data from the EPIC II study.

Surg Infect (Larchmt) 2014 Aug 12;15(4):394-8. Epub 2014 May 12.

1 Department of Critical Care Medicine, Ghent Medical School and University Hospital , Ghent, Belgium .

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https://www.liebertpub.com/doi/10.1089/sur.2012.228
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http://dx.doi.org/10.1089/sur.2012.228DOI Listing
August 2014

Does consistent piperacillin dosing result in consistent therapeutic concentrations in critically ill patients? A longitudinal study over an entire antibiotic course.

Int J Antimicrob Agents 2014 May 15;43(5):470-3. Epub 2014 Mar 15.

Department of Critical Care Medicine, Ghent University Hospital, De Pintelaan 185, Ghent 9000, Belgium.

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http://dx.doi.org/10.1016/j.ijantimicag.2014.01.028DOI Listing
May 2014

Acute pancreatitis.

Authors:
Jan J De Waele

Curr Opin Crit Care 2014 Apr;20(2):189-95

Ghent University Hospital, Department of Critical Care Medicine, Ghent, Belgium.

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http://dx.doi.org/10.1097/MCC.0000000000000068DOI Listing
April 2014

Therapeutic drug monitoring-based dose optimisation of piperacillin and meropenem: a randomised controlled trial.

Intensive Care Med 2014 Mar 20;40(3):380-7. Epub 2013 Dec 20.

Department of Critical Care Medicine, Ghent University Hospital, De Pintelaan 185, 9000, Ghent, Belgium,

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http://link.springer.com/content/pdf/10.1007/s00134-013-3187
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http://link.springer.com/10.1007/s00134-013-3187-2
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http://dx.doi.org/10.1007/s00134-013-3187-2DOI Listing
March 2014

Population pharmacokinetics and dosing simulations of amoxicillin/clavulanic acid in critically ill patients.

J Antimicrob Chemother 2013 Nov 25;68(11):2600-8. Epub 2013 Jun 25.

Department of Clinical Chemistry, Microbiology and Immunology, Ghent University, Ghent, Belgium.

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http://dx.doi.org/10.1093/jac/dkt240DOI Listing
November 2013

Augmented renal clearance is a common finding with worse clinical outcome in critically ill patients receiving antimicrobial therapy.

J Crit Care 2013 Oct 14;28(5):695-700. Epub 2013 May 14.

Pharmacy Department, Ghent University Hospital, Pharmacy, 9000 Ghent, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.jcrc.2013.03.003DOI Listing
October 2013

Intra-abdominal hypertension: definitions, monitoring, interpretation and management.

Best Pract Res Clin Anaesthesiol 2013 Jun;27(2):249-70

Intensive Care Unit, ZiekenhuisNetwerk Antwerpen, ZNA Stuivenberg, Lange Beeldekensstraat 267, B-2060 Antwerpen, Belgium.

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http://dx.doi.org/10.1016/j.bpa.2013.06.009DOI Listing
June 2013

Quantification of seven β-lactam antibiotics and two β-lactamase inhibitors in human plasma using a validated UPLC-MS/MS method.

Int J Antimicrob Agents 2012 Nov 10;40(5):416-22. Epub 2012 Aug 10.

Department of Clinical Chemistry, Microbiology and Immunology, Ghent University, De Pintelaan 185, Building 2P8, 9000 Ghent, Belgium.

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http://dx.doi.org/10.1016/j.ijantimicag.2012.06.022DOI Listing
November 2012

Management of necrotizing skin and soft tissue infections.

Authors:
Jan J De Waele

Expert Rev Anti Infect Ther 2012 Jul;10(7):805-14

Department of Critical Care Medicine, Ghent University Hospital, De Pintelaan 185, 9000 Gent, Belgium.

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http://dx.doi.org/10.1586/eri.12.64DOI Listing
July 2012

Essentials for selecting antimicrobial therapy for intra-abdominal infections.

Drugs 2012 Apr;72(6):e17-32

Faculty of Medicine & Health Sciences, Ghent University, Ghent, Belgium.

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http://dx.doi.org/10.2165/11599800-000000000-00000DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3585770PMC
April 2012

Serum urea concentration is probably not related to outcome in ICU patients with AKI and renal replacement therapy.

Nephrol Dial Transplant 2011 Oct 18;26(10):3211-8. Epub 2011 Mar 18.

Department of Intensive Care Medicine, Ghent University Hospital, Ghent University, Ghent, Belgium.

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http://dx.doi.org/10.1093/ndt/gfq840DOI Listing
October 2011

Nonoperative management of intra-abdominal hypertension and abdominal compartment syndrome: evolving concepts.

Am Surg 2011 Jul;77 Suppl 1:S34-41

Intensive Care Unit, Fremantle Hospital, 1 Alma Street, Fremantle, WA 6160, Australia.

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July 2011

Temporary abdominal closure techniques.

Am Surg 2011 Jul;77 Suppl 1:S46-50

Department of Critical Care Medicine, Ghent UniversityHospital, De Pintelaan 185, Gent, Belgium.

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July 2011

Rational use of antimicrobials in patients with severe acute pancreatitis.

Authors:
Jan J De Waele

Semin Respir Crit Care Med 2011 Apr 19;32(2):174-80. Epub 2011 Apr 19.

Department of Critical Care Medicine, Ghent University Hospital, Ghent, Belgium.

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http://dx.doi.org/10.1055/s-0031-1275529DOI Listing
April 2011

Clinical review: Intra-abdominal hypertension: does it influence the physiology of prone ventilation?

Crit Care 2010 27;14(4):232. Epub 2010 Aug 27.

Regional Trauma Services, Foothills Medical Centre, 1403 29 Street NW, Calgary, Alberta, Canada.

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http://dx.doi.org/10.1186/cc9099DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2945095PMC
January 2011

Intra-abdominal Hypertension and Abdominal Compartment Syndrome.

Am J Kidney Dis 2011 Jan;57(1):159-69

Department of Critical Care Medicine, Ghent University Hospital, Belgium.

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http://dx.doi.org/10.1053/j.ajkd.2010.08.034DOI Listing
January 2011

De-escalation after empirical meropenem treatment in the intensive care unit: fiction or reality?

J Crit Care 2010 Dec 15;25(4):641-6. Epub 2010 Jan 15.

Department of Critical Care Medicine, Ghent University Hospital, 9000 Ghent, Belgium.

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http://dx.doi.org/10.1016/j.jcrc.2009.11.007DOI Listing
December 2010

Acute pancreatitis: radiologic scores in predicting severity and outcome.

Abdom Imaging 2010 Jun 13;35(3):349-61. Epub 2009 May 13.

Department of Radiology, Ghent University Hospital, Belgium.

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http://dx.doi.org/10.1007/s00261-009-9522-yDOI Listing
June 2010

Early source control in sepsis.

Authors:
Jan J De Waele

Langenbecks Arch Surg 2010 Jun 2;395(5):489-94. Epub 2010 Jun 2.

Department of Critical Care Medicine, Ghent University Hospital, De Pintelaan 185, 9000, Gent, Belgium.

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http://dx.doi.org/10.1007/s00423-010-0650-1DOI Listing
June 2010

Thrombocytopenia and outcome in critically ill patients with bloodstream infection.

Heart Lung 2010 Jan-Feb;39(1):21-6. Epub 2009 Oct 15.

Department of Intensive Care Medicine, Ghent University Hospital, Ghent, Belgium.

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http://dx.doi.org/10.1016/j.hrtlng.2009.07.005DOI Listing
April 2010

Sodium bicarbonate for prevention of contrast-induced acute kidney injury: a systematic review and meta-analysis.

Nephrol Dial Transplant 2010 Mar 23;25(3):747-58. Epub 2009 Aug 23.

Intensive Care Unit, Ghent University Hospital, Gent, Belgium.

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http://dx.doi.org/10.1093/ndt/gfp389DOI Listing
March 2010

Use of antibiotics in severe acute pancreatitis.

Authors:
Jan J De Waele

Expert Rev Anti Infect Ther 2010 Mar;8(3):317-24

Department of Critical Care Medicine, Intensive Care Unit 1K12-C, Ghent University Hospital, De Pintelaan 185, 9000 Ghent, Belgium.

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http://dx.doi.org/10.1586/eri.10.3DOI Listing
March 2010

Epidemiology of infection in critically ill patients with acute renal failure.

Crit Care Med 2009 Jul;37(7):2203-9

Department of Medicine and Health Sciences, Ghent University, Ghent, Belgium.

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http://dx.doi.org/10.1097/CCM.0b013e3181a03961DOI Listing
July 2009

Intra-abdominal hypertension in acute pancreatitis.

World J Surg 2009 Jun;33(6):1128-33

Department of Critical Care Medicine, Ghent University Hospital, De Pintelaan 185, 9000, Gent, Belgium.

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http://dx.doi.org/10.1007/s00268-009-9994-5DOI Listing
June 2009

IAH/ACS: the rationale for surveillance.

World J Surg 2009 Jun;33(6):1110-5

ZNA Stuivenberg Hospital, Lange Beeldekensstraat 267, 2060, Antwerp, Belgium.

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http://link.springer.com/content/pdf/10.1007/s00268-009-0039
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http://dx.doi.org/10.1007/s00268-009-0039-xDOI Listing
June 2009