Jan Hillert

Jan Hillert

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Jan Hillert

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Stressful life events are associated with the risk of multiple sclerosis.

Eur J Neurol 2020 Aug 2. Epub 2020 Aug 2.

Department of Clinical Neuroscience, Karolinska Institute, Centrum for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1111/ene.14458DOI Listing
August 2020

Diagnosis-specific sickness absence and disability pension before and after multiple sclerosis diagnosis: An 8-year nationwide longitudinal cohort study with matched references.

Mult Scler Relat Disord 2020 Jul 13;42:102077. Epub 2020 Apr 13.

Division of Insurance Medicine, Department of Clinical Neuroscience, Karolinska Institutet, SE-171 77 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.msard.2020.102077DOI Listing
July 2020

Smoking and Epstein-Barr virus infection in multiple sclerosis development.

Sci Rep 2020 Jul 3;10(1):10960. Epub 2020 Jul 3.

Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1038/s41598-020-67883-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7335184PMC
July 2020

A topological data analysis based classification method for multiple measurements.

BMC Bioinformatics 2020 Jul 29;21(1):336. Epub 2020 Jul 29.

KTH-The Royal Institute of Technology, Stockholm, Sweden.

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http://dx.doi.org/10.1186/s12859-020-03659-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7392670PMC
July 2020

Low fish consumption is associated with a small increased risk of MS.

Neurol Neuroimmunol Neuroinflamm 2020 May 10;7(3). Epub 2020 Apr 10.

From the Department of Clinical Neuroscience (A.K.H., T.O., I.K., J.H.), Institute of Environmental Medicine (A.K.H., L.A.), Center for Molecular Medicine (T.O., I.K., J.H.), Karolinska Institutet, Stockholm, Sweden; and Centre for Occupational and Environmental Medicine (L.A.), Region Stockholm, Stockholm, Sweden.

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http://dx.doi.org/10.1212/NXI.0000000000000717DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7176247PMC
May 2020

Low sun exposure increases multiple sclerosis risk both directly and indirectly.

J Neurol 2020 Apr 17;267(4):1045-1052. Epub 2019 Dec 17.

Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1007/s00415-019-09677-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7109160PMC
April 2020

Socioeconomic status and multiple sclerosis outcome.

Authors:
Jan Hillert

Nat Rev Neurol 2020 04;16(4):191-192

Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1038/s41582-020-0329-3DOI Listing
April 2020

Determinants of quality of life in pediatric- and adult-onset multiple sclerosis.

Neurology 2020 03 15;94(9):e932-e941. Epub 2019 Nov 15.

From the Departments of Clinical Neuroscience (K.A.M., A.M., T.O., J.H.) and Learning, Informatics, Management and Ethics (O.E.), Karolinska Institutet; and Centre for Molecular Medicine (K.A.M., A.M., T.O.), Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1212/WNL.0000000000008667DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7238943PMC
March 2020

Patients With High-disease-activity Relapsing-Remitting Multiple Sclerosis in Real-world Clinical Practice: A Population-based Study in Sweden.

Clin Ther 2020 02 31;42(2):240-250. Epub 2019 Dec 31.

Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.clinthera.2019.11.018DOI Listing
February 2020

Confounding effect of blood volume and body mass index on blood neurofilament light chain levels.

Ann Clin Transl Neurol 2020 01 1;7(1):139-143. Epub 2020 Jan 1.

Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1002/acn3.50972DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6952306PMC
January 2020

Validation of multiple sclerosis diagnoses in the Swedish National Patient Register.

Eur J Epidemiol 2019 Dec 6;34(12):1161-1169. Epub 2019 Sep 6.

Division of Insurance Medicine, Department of Clinical Neuroscience, Karolinska Institutet, 171 77, Stockholm, Sweden.

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http://dx.doi.org/10.1007/s10654-019-00558-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7010617PMC
December 2019

Disability worsening among persons with multiple sclerosis and depression: A Swedish cohort study.

Neurology 2019 12 8;93(24):e2216-e2223. Epub 2019 Nov 8.

From the Department of Clinical Neuroscience (S.B., K.A.M., J.H., A.M.), Department of Medicine Solna (P.B.), and Karolinska Neuroimmunology & Multiple Sclerosis Centre and Centre for Molecular Medicine (A.M.) Karolinska Institutet, Stockholm, Sweden, Odense University Hospital (S.B.), Department of Neurology, Denmark; and Karolinska University Hospital (J.H.), Stockholm, Sweden.

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http://dx.doi.org/10.1212/WNL.0000000000008617DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937491PMC
December 2019

Retinal nerve fiber layer thickness associates with cognitive impairment and physical disability in multiple sclerosis.

Mult Scler Relat Disord 2019 Nov 26;36:101414. Epub 2019 Sep 26.

Unit of Optometry, Department of Clinical Neuroscience, Karolinska Institutet, Box 8056, S-104 20 Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.msard.2019.101414DOI Listing
November 2019

The influence of human leukocyte antigen-DRB1*15:01 and its interaction with smoking in MS development is dependent on DQA1*01:01 status.

Mult Scler 2019 Oct 1:1352458519877685. Epub 2019 Oct 1.

Institute of Environmental Medicine, Karolinska Institute, Stockholm, Sweden.

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http://dx.doi.org/10.1177/1352458519877685DOI Listing
October 2019

Predicting risk of secondary progression in multiple sclerosis: A nomogram.

Mult Scler 2019 07 18;25(8):1102-1112. Epub 2018 Jun 18.

Department of Clinical Neuroscience (CNS), Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1177/1352458518783667DOI Listing
July 2019

Factors associated with and long-term outcome of benign multiple sclerosis: a nationwide cohort study.

J Neurol Neurosurg Psychiatry 2019 07 1;90(7):761-767. Epub 2019 Mar 1.

The Karolinska Neuroimmunology & Multiple Sclerosis Centre, Centre for Molecular Medicine, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden

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http://dx.doi.org/10.1136/jnnp-2018-319913DOI Listing
July 2019

Long-term disability progression of pediatric-onset multiple sclerosis.

Neurology 2019 06 15;92(24):e2764-e2773. Epub 2019 May 15.

From the Department of Clinical Neuroscience (K.A.M., J.H., A.M.), Karolinska Institutet; and Centre for Molecular Medicine (A.M.), Karolinska Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1212/WNL.0000000000007647DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598792PMC
June 2019

Long-term Cognitive Outcomes in Patients With Pediatric-Onset vs Adult-Onset Multiple Sclerosis.

JAMA Neurol 2019 Jun 17. Epub 2019 Jun 17.

Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1001/jamaneurol.2019.1546DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580443PMC
June 2019

Costs of illness progression for different multiple sclerosis phenotypes: a population-based study in Sweden.

Mult Scler J Exp Transl Clin 2019 Apr-Jun;5(2):2055217319858383. Epub 2019 Jun 28.

Department of Clinical Neuroscience, Karolinska Institutet, Sweden.

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http://dx.doi.org/10.1177/2055217319858383DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6600515PMC
June 2019

The association between multiple sclerosis and pain medications.

Pain 2019 Feb;160(2):424-432

Centre for Pharmacoepidemiology, Department of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden.

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http://Insights.ovid.com/crossref?an=00006396-900000000-9882
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http://dx.doi.org/10.1097/j.pain.0000000000001429DOI Listing
February 2019

Familial risk of early- and late-onset multiple sclerosis: a Swedish nationwide study.

J Neurol 2019 Feb 21;266(2):481-486. Epub 2018 Dec 21.

Centre for Molecular Medicine, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.

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http://link.springer.com/10.1007/s00415-018-9163-6
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http://dx.doi.org/10.1007/s00415-018-9163-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6373346PMC
February 2019

Cognitive function is a major determinant of income among multiple sclerosis patients in Sweden acting independently from physical disability.

Mult Scler 2019 01 16;25(1):104-112. Epub 2017 Nov 16.

Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden/Department of Neurology, Karolinska University Hospital, Stockholm, Sweden/Centre for Molecular Medicine, Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1177/1352458517740212DOI Listing
January 2019

Cognitive function predicts work disability among multiple sclerosis patients.

Mult Scler J Exp Transl Clin 2019 Jan-Mar;5(1):2055217318822134. Epub 2019 Jan 14.

Department of Clinical Neuroscience, Karolinska Institutet, Sweden.

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http://dx.doi.org/10.1177/2055217318822134DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350142PMC
January 2019

The Swedish motor neuron disease quality registry.

Amyotroph Lateral Scler Frontotemporal Degener 2018 11 9;19(7-8):528-537. Epub 2018 Oct 9.

b Department of Neurology , Karolinska University Hospital , Stockholm , Sweden.

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https://www.tandfonline.com/doi/full/10.1080/21678421.2018.1
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http://dx.doi.org/10.1080/21678421.2018.1497065DOI Listing
November 2018

Rituximab is an acceptable alternative to ocrelizumab for treating multiple sclerosis - Yes.

Mult Scler 2018 08 22;24(9):1157-1159. Epub 2018 Feb 22.

Department of Clinical Neuroscience, Karolinska Institute, Stockholm, Sweden/Department of Neurology, Karolinska University Hospital, Stockholm, Sweden.

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http://dx.doi.org/10.1177/1352458518757930DOI Listing
August 2018

The long-term impact of multiple sclerosis on the risk of divorce.

Mult Scler Relat Disord 2018 Aug 3;24:145-150. Epub 2018 Jul 3.

Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.msard.2018.07.002DOI Listing
August 2018

Comparative effectiveness of rituximab relative to IFN-β or glatiramer acetate in relapsing-remitting MS from the Swedish MS registry.

Mult Scler 2018 07 26;24(8):1087-1095. Epub 2017 Jun 26.

Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1177/1352458517713668DOI Listing
July 2018

Costs and quality of life by disability among people with multiple sclerosis: a register-based study in Sweden.

Mult Scler J Exp Transl Clin 2018 Jul-Sep;4(3):2055217318783352. Epub 2018 Jul 9.

Department of Clinical Neuroscience, Karolinska Institutet, Sweden.

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http://dx.doi.org/10.1177/2055217318783352DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6077913PMC
July 2018

Characterization of annual disease progression of multiple sclerosis patients: A population-based study.

Mult Scler 2018 05 8;24(6):786-794. Epub 2017 May 8.

Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1177/1352458517706252DOI Listing
May 2018

Personal Income Before and After Diagnosis of Multiple Sclerosis.

Value Health 2018 05 15;21(5):590-595. Epub 2017 Nov 15.

Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.jval.2017.09.021DOI Listing
May 2018

Association of Pre-Disease Body Mass Index With Multiple Sclerosis Prognosis.

Front Neurol 2018 11;9:232. Epub 2018 May 11.

Department of Clinical Neuroscience, Karolinska Institutet, Karolinska University Hospital Solna, Stockholm, Sweden.

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http://dx.doi.org/10.3389/fneur.2018.00232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5958198PMC
May 2018

Comparing costs of illness of multiple sclerosis in three different years: A population-based study.

Mult Scler 2018 04 3;24(4):520-528. Epub 2017 Apr 3.

Division of Insurance Medicine, Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden/Department of Public Health and Medicine, Swedish Red Cross University College, Stockholm, Sweden.

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http://dx.doi.org/10.1177/1352458517702549DOI Listing
April 2018

Costs of illness of multiple sclerosis in Sweden: a population-based register study of people of working age.

Eur J Health Econ 2018 Apr 9;19(3):435-446. Epub 2017 May 9.

Department of Clinical Neuroscience, Karolinska Institutet, Berzelius Väg 3, Floor 6, SE-171 77, Stockholm, Sweden.

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http://dx.doi.org/10.1007/s10198-017-0894-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5978901PMC
April 2018

Multiple sclerosis treatment effects on plasma cytokine receptor levels.

Clin Immunol 2018 02 21;187:15-25. Epub 2017 Sep 21.

Department of Clinical Neuroscience and Centrum for Molecular Medicine, Karolinska Institutet, Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.clim.2017.08.023DOI Listing
February 2018

Multiple Sclerosis Patients with Markedly Low Intrathecal Antibody Response in Sri Lanka.

Mult Scler Int 2018 28;2018:5342936. Epub 2018 Feb 28.

Department of Anatomy, Faculty of Medicine, University of Peradeniya, Peradeniya, Sri Lanka.

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http://dx.doi.org/10.1155/2018/5342936DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5851020PMC
February 2018

Age Related Multiple Sclerosis Severity Score: Disability ranked by age.

Mult Scler 2017 Dec 3;23(14):1938-1946. Epub 2017 Feb 3.

Department of Clinical Neuroscience (CNS), Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1177/1352458517690618DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5700773PMC
December 2017

Similar familial risk in multiple sclerosis subgroups.

Mult Scler 2017 Nov 16;23(13):1782-1785. Epub 2017 Jan 16.

Institute of Environmental Medicine (IMM), Karolinska Institutet, Stockholm, Sweden/Rheumatology Unit, Department of Medicine Solna, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1177/1352458516684214DOI Listing
November 2017

Clinical course of multiple sclerosis: A nationwide cohort study.

Mult Scler 2017 Oct 12;23(11):1488-1495. Epub 2016 Dec 12.

Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1177/1352458516681197DOI Listing
October 2017

Importance of early treatment initiation in the clinical course of multiple sclerosis.

Mult Scler 2017 Aug 17;23(9):1233-1240. Epub 2016 Oct 17.

Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1177/1352458516675039DOI Listing
August 2017

Mortality trends for multiple sclerosis patients in Sweden from 1968 to 2012.

Neurology 2017 Aug 7;89(6):555-562. Epub 2017 Jul 7.

From the Clinical Epidemiology Unit (S.B., S.M., M.H., S.B) and Centre for Pharmacoepidemiology (S.B., S.B.), Department of Medicine, Solna, Karolinska Institutet, Stockholm; Clinical Epidemiology and Biostatistics (S.M.), School of Medical Sciences, Örebro University, Sweden; Department of Epidemiology and Public Health (S.M.), University College London, UK; Division of Neurology (J.H.) and Neuroimmunology Unit (T.O.), Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden; and Biostatistics and Epidemiology Unit (M.H., S.B.), Health Faculty, Golestan University of Medical Sciences, Golestan, Iran.

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http://dx.doi.org/10.1212/WNL.0000000000004216DOI Listing
August 2017

Evidence for a causal relationship between low vitamin D, high BMI, and pediatric-onset MS.

Neurology 2017 Apr 29;88(17):1623-1629. Epub 2017 Mar 29.

From the Division of Epidemiology, School of Public Health (M.A.G., X.S., E.X., H.Q., D.Q., C.M., L.F.B.), and Computational Biology Graduate Group (B.R.), University of California, Berkeley; Department of Clinical Neuroscience and Center for Molecular Medicine (P.S.), Karolinska Institutet at Karolinska University Hospital, Stockholm, Sweden; Department of Neurology (J.S.G., E.W.) and Regional Pediatric MS Center, Neurology (J.H., S.C.), University of California, San Francisco; Partners Pediatric Multiple Sclerosis Center (T.C.), Massachusetts General Hospital for Children, Boston; Division of Neurology (A.W.), Children's Hospital of Philadelphia, PA; Blue Bird Circle Multiple Sclerosis Center (T.L.), Baylor College of Medicine, Houston, TX; Children's Hospital Colorado (T.S.), University of Colorado, Denver; Lourie Center for Pediatric Multiple Sclerosis (A.B., L.K.), Stony Brook Children's Hospital, NY; Department of Neurology (B.G.), University of Texas Southwestern, Dallas; Pediatric Multiple Sclerosis Center (B.W.-G.), Jacobs Neurological Institute, SUNY Buffalo, NY; Pediatric MS Center at Loma Linda University Children's Hospital (G.A.), CA; Mayo Clinic's Pediatric Multiple Sclerosis Center (J.M.T., M.R.), Rochester, MN; University of Alabama Center for Pediatric-onset Demyelinating Disease (J.N., Y.H.), Children's Hospital of Alabama, Birmingham; Department of Pediatric Neurology (J.R.), Northwestern Feinberg School of Medicine, Chicago, IL; Primary Children's Hospital (M.C.), University of Utah, Salt Lake City; Boston Children's Hospital (M.G., L.B.), MA; Pediatric-onset Demyelinating Diseases and Autoimmune Encephalitis Center (S.M.), St. Louis Children's Hospital, Washington University School of Medicine, MO; Children's National Medical Center (I.K.), Washington, DC; Departments of Neurology (J.R.) and Pediatrics (S.R., T.C.C.), University of Utah School of Medicine, Salt Lake City; Kaiser Permanente Division of Research (L.S., C.S., L.F.B.), Oakland, CA; Institute of Environmental Medicine (J.H., M.B., A.H., T.O., I.K., L.A.), Karolinska Institutet; Centre for Occupational and Environmental Medicine (L.A.), Stockholm County Council, Stockholm, Sweden; and Research Program on Genes, Environment and Health (C.S.), Kaiser Permanente, Oakland, CA.

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http://dx.doi.org/10.1212/WNL.0000000000003849DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5405763PMC
April 2017

Overexpression of the Cytokine BAFF and Autoimmunity Risk.

N Engl J Med 2017 04;376(17):1615-1626

From Istituto di Ricerca Genetica e Biomedica, Consiglio Nazionale delle Ricerche Monserrato (M.S., V.O., M.L.I., M. Pitzalis, M. Pala, C.S., V.F., M.F., M. Deiana, I.A., E.P., A. Mulas, M.G.P., M. Lobina, S.L., Mara Marongiu, V.S., Michele Marongiu, G.S., F.B., A. Maschio, F.D., M. Dei, F.V., S.O., A.A., M.B.W., A. Meloni, S. Sanna, E.F., M.Z., F.C.), Center for Advanced Studies, Research, and Development in Sardinia, Parco Scientifico e Tecnologico della Sardegna (I.Z., M.F., R.C., G. Cuccuru), Struttura Complessa Disciplina di Ematologia e Centro Trapianto Cellule Staminali Emopoietiche Wilma Deplano, Ospedale Oncologico di Riferimento Regionale Armando Businco (M. Pani), Dipartimento di Sanità Pubblica, Medicina Clinica e Molecolare, Università di Cagliari (E.C., J.F., G. Coghe, L.L., G. Fenu), Azienda Ospedaliera Brotzu, S.C. Neurologia (P.F., M. Melis), Division of Rheumatology, University and University Hospital of Cagliari (M. Piga, A. Mathieu), Department of Medical Sciences M. Aresu, University of Cagliari (D.F., S.D.G., M.G.M.), Azienda Ospedaliera Brotzu, U.S. Gastroenterologia Pediatrica Ospedale Pediatrico Microcitemico A. Cao (M.C.), and Nephrology, Dialysis, and Transplantation Unit, Giuseppe Brotzu Hospital (A.P.), Cagliari, Dipartimento di Scienze Biomediche, Università degli Studi di Sassari (M.F., F.P., F.C.), Unit of Neurology, Department of Clinical and Experimental Medicine, University of Sassari (G. Farina, G.R.), and Servizio Trasfusionale (M.A.S.) and Clinica Medica (A.D.), Azienda Ospedaliero Universitaria di Sassari, Sassari, Neurology B, Department of Neurological, Biomedical, and Movement Sciences, University of Verona, Verona (G. Farina), Department of Health Sciences, Interdisciplinary Research Center of Autoimmune Diseases, University of Eastern Piedmont, Novara (N.B., S.D.), SC Neurologia, Dipartimento di Scienze Mediche, Istituti di Ricovero e Cura a Carattere Scientifico (IRCCS) Casa Sollievo della Sofferenza, San Giovanni Rotondo (M. Leone), Don C. Gnocchi Foundation IRCCS (F.R.G.), and Referral Center for Systemic Autoimmune Diseases Fondazione IRCCS Cá Granda Ospedale Maggiore Policlinico and University of Milan (M. Marchini), Milan, and Dipartimento di Scienze Cliniche e Molecolari, Università Politecnica delle Marche e Ospedali Riuniti, Ancona (M.G.D.) - all in Italy; Laboratory of Genetics and Genomics, National Institute on Aging, National Institutes of Health, Baltimore (M.L.I., M.G., D.S.); the Department of Clinical Neurosciences (M.B., S. Sawcer) and JDRF-Wellcome Trust Diabetes and Inflammation Laboratory, National Institute for Health Research Cambridge Biomedical Research Centre, Cambridge Institute for Medical Research (J.A.T.), University of Cambridge, Cambridge, United Kingdom; Department of Clinical Neuroscience, Karolinska Institutet at Karolinska University Hospital Solna (I.K., I.L.B., T.O., J.H.), Institute of Environmental Medicine (L.A.) and Institute of Environmental Medicine, Unit of Immunology and Chronic Disease (M.E.A.R.), Karolinska Institute, and Center for Occupational and Environmental Medicine, Stockholm County Council (L.A.), Stockholm; Department of Functional Biology, University of Oviedo, Oviedo (A.S.), Rheumatology Department, Hospital Universitario 12 de Octubre, Madrid (P.E.C.), Department of Internal Medicine, Hospital Universitario Virgen del Rocío, Seville (M.J.C.-P.), Laboratorio de Investigacion 10 and Rheumatology Unit, Instituto de Investigacion Sanitaria-Hospital Clinico Universitario de Santiago, Santiago de Compostela (A.G.), and Centro de Genómica e Investigación Oncológica, Pfizer-Universidad de Granada-Junta de Andalucía, Granada (M.E.A.R.) - all in Spain; Department of Human Genetics, University of Chicago, Chicago (J.H.M., J.N.); Centro Hospitalar do Porto-Hospital Santo Antonio and Unit for Multidisciplinary Research in Biomedicine-Unidade Multidisciplinar de Investigação Biomédica, Porto, Portugal (B.M.S.); Departments of Pathology and Genetics, Stanford University, Stanford, CA (S.B.M.); and Center for Statistical Genetics, University of Michigan, Ann Arbor (G.R.A.).

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http://dx.doi.org/10.1056/NEJMoa1610528DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5605835PMC
April 2017

Re: Declines in the diagnosis of primary progressive MS-A critical change in phenotype or critical measurement error?

Mult Scler 2017 02 28;23(2):305-307. Epub 2016 Sep 28.

2 Department of Clinical Neuroscience (CNS), Karolinska Institutet, Stockholm, Sweden.

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http://journals.sagepub.com/doi/10.1177/1352458516669863
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http://dx.doi.org/10.1177/1352458516669863DOI Listing
February 2017

Treatment decisions in multiple sclerosis - insights from real-world observational studies.

Nat Rev Neurol 2017 Feb 13;13(2):105-118. Epub 2017 Jan 13.

Department of Medicine, University of Melbourne, and Department of Neurology, Royal Melbourne Hospital, Grattan Street, Parkville, VIC 3050, Australia.

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http://dx.doi.org/10.1038/nrneurol.2016.188DOI Listing
February 2017

The External Validity of Mapping MSIS-29 on EQ-5D Among Individuals With Multiple Sclerosis in Sweden.

MDM Policy Pract 2017 Jan-Jun;2(1):2381468317692806. Epub 2017 Feb 1.

Health Outcomes and Economic Evaluation Research Group, Medical Management Centre, Department of Learning, Informatics, Management and Ethics (OE, KB), Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1177/2381468317692806DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132828PMC
February 2017

Sick leave and disability pension before and after diagnosis of multiple sclerosis.

Mult Scler 2016 12 20;22(14):1859-1866. Epub 2016 Sep 20.

Department of Clinical Neuroscience, Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1177/1352458516667567DOI Listing
December 2016

Mendelian randomization shows a causal effect of low vitamin D on multiple sclerosis risk.

Neurol Genet 2016 Oct 13;2(5):e97. Epub 2016 Sep 13.

Computational Biology Graduate Group (B.R.), Division of Epidemiology (M.G., A.M., X.S., H.Q., L.F.B.), School of Public Health, University of California, Berkeley; Institute of Environmental Medicine (M.B., A.K.H., L.A.), Karolinska Institutet, Stockholm, Sweden; Kaiser Permanente Division of Research (L.S., C.S., L.F.B.), Research Program on Genes, Environment, and Health (C.S.), Kaiser Permanente, Oakland, CA; Department of Clinical Neuroscience and Center for Molecular Medicine (J.L., A.G., T.O., J.H., I.K.), Karolinska Institutet at Karolinska University Hospital, Stockholm, Sweden; Department of Epidemiology and Biostatistics (M.M.G.), University of California, San Francisco; and Centre for Occupational and Environmental Medicine (L.A.), Stockholm County Council, Sweden.

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http://dx.doi.org/10.1212/NXG.0000000000000097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5022843PMC
October 2016

Longitudinal changes in sickness absence and disability pension, and associations between disability pension and disease-specific and contextual factors and functioning, in people with multiple sclerosis.

J Neurol Sci 2016 Aug 12;367:319-25. Epub 2016 Jun 12.

Division of Physiotherapy, Department of Neurobiology, Care Sciences and Society, Karolinska Institutet, SE - 141 83 Stockholm, Sweden; Department of Physiotherapy, Karolinska University Hospital, SE - 141 86 Stockholm, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.jns.2016.05.055DOI Listing
August 2016

A significant decrease in diagnosis of primary progressive multiple sclerosis: A cohort study.

Mult Scler 2016 07 12;22(8):1071-9. Epub 2016 Apr 12.

Department of Clinical Neuroscience (CNS), Karolinska Institutet, Stockholm, Sweden.

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http://dx.doi.org/10.1177/1352458516643394DOI Listing
July 2016

Prescribed psychiatric medication among multiple sclerosis patients before and after disability pension: a register study with matched controls.

Soc Psychiatry Psychiatr Epidemiol 2016 07 11;51(7):1047-54. Epub 2016 May 11.

Division of Insurance Medicine, Department of Clinical Neuroscience, Karolinska Institutet, 171 77, Stockholm, Sweden.

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http://dx.doi.org/10.1007/s00127-016-1234-3DOI Listing
July 2016

Multiple sclerosis and risk of young-adult-onset Hodgkin lymphoma.

Neurol Neuroimmunol Neuroinflamm 2016 Jun 14;3(3):e227. Epub 2016 Apr 14.

Clinical Epidemiology and Biostatistics (S.M.), School of Medical Sciences, Örebro University, Sweden; Department of Epidemiology and Public Health (S.M.), University College London, UK; Clinical Epidemiology Unit (S.M., M.H.H., S. Burkill, S. Bahmanyar) and Centre for Pharmacoepidemiology (S. Bahmanyar), Department of Medicine, Solna, Karolinska Institutet; Department of Neurology (J.H., T.O.), Karolinska University Hospital Huddinge, Stockholm; Neuroimmunology Unit (J.H.), Department of Clinical Neuroscience and Centre for Molecular Medicine, Karolinska Institutet and Karolinska University Hospital, Solna, Sweden; and Faculty of Medicine (S. Bahmanyar), Golestan University of Medical Sciences, Gorgan, Iran.

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http://nn.neurology.org/lookup/doi/10.1212/NXI.0000000000000
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http://dx.doi.org/10.1212/NXI.0000000000000227DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4841639PMC
June 2016

The importance of collecting structured clinical information on multiple sclerosis.

BMC Med 2016 May 31;14:81. Epub 2016 May 31.

Department of Neurology, Royal Melbourne Hospital, Victoria, Australia.

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http://dx.doi.org/10.1186/s12916-016-0627-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4888646PMC
May 2016

Effect of Smoking Cessation on Multiple Sclerosis Prognosis.

JAMA Neurol 2015 Oct;72(10):1117-23

Department of Clinical Neuroscience, Karolinska Institutet at Karolinska University Hospital Solna, Stockholm, Sweden.

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http://dx.doi.org/10.1001/jamaneurol.2015.1788DOI Listing
October 2015

Heterogeneity of sickness absence and disability pension trajectories among individuals with MS.

Mult Scler J Exp Transl Clin 2015 Jan-Dec;1:2055217315595638. Epub 2015 Jul 24.

Division of Insurance Medicine, Department of Clinical Neuroscience, Karolinska Institutet, Sweden.

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http://dx.doi.org/10.1177/2055217315595638DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5433496PMC
July 2015

Age-dependent effects on the treatment response of natalizumab in MS patients.

Mult Scler 2015 Jan 27;21(1):48-56. Epub 2014 May 27.

Karolinska University Hospital, Sweden.

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http://dx.doi.org/10.1177/1352458514536085DOI Listing
January 2015

Multiple sclerosis patients lacking oligoclonal bands in the cerebrospinal fluid have less global and regional brain atrophy.

J Neuroimmunol 2014 Sep 26;274(1-2):149-54. Epub 2014 Jun 26.

Department of Clinical Neuroscience (Karolinska Institutet), Center for Molecular Medicine (CMM), L8:00, 171 76, Stockholm, Sweden.

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http://dx.doi.org/10.1016/j.jneuroim.2014.06.010DOI Listing
September 2014

[Every fifth case of multiple sclerosis is familial].

Ugeskr Laeger 2014 Jan;176(3A):V04130245

Neurologisk Ambulatorium, Forskningsenheden, Sygehus Sønderjylland, Sydvang 1, 6400 Sønderborg.

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January 2014