Publications by authors named "Jan C M van Hest"

187Publications

Terpolymer-stabilized complex coacervates: A robust and versatile synthetic cell platform.

Methods Enzymol 2021 9;646:51-82. Epub 2020 Jul 9.

Department of Biomedical Engineering, Institute for Complex Molecular Systems, Eindhoven University of Technology, Eindhoven, The Netherlands; Department of Chemical Engineering and Chemistry, Institute for Complex Molecular Systems, Eindhoven University of Technology, Eindhoven, The Netherlands. Electronic address:

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July 2020

Engineered protein cages for selective heparin encapsulation.

J Mater Chem B 2021 Jan 11. Epub 2021 Jan 11.

Department of Bioproducts and Biosystems, Aalto University, P.O. Box 16100, Aalto FI-00076, Espoo, Finland. and HYBER Centre, Department of Applied Physics, Aalto University, Aalto FI-00076, Finland.

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January 2021

Programmed spatial organization of biomacromolecules into discrete, coacervate-based protocells.

Nat Commun 2020 12 8;11(1):6282. Epub 2020 Dec 8.

Department of Biomedical Engineering, Eindhoven University of Technology, PO Box 513, 5600 MB, Eindhoven, The Netherlands.

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December 2020

Scale-Up of the Manufacturing Process To Produce Docetaxel-Loaded mPEG--p(HPMA-Bz) Block Copolymer Micelles for Pharmaceutical Applications.

Org Process Res Dev 2019 Dec 29;23(12):2707-2715. Epub 2019 Oct 29.

Department of Bio-Organic chemistry, Eindhoven University of Technology, 5600 MB Eindhoven, The Netherlands.

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December 2019

Surface-Charge-Switchable Nanoclusters for Magnetic Resonance Imaging-Guided and Glutathione Depletion-Enhanced Photodynamic Therapy.

ACS Nano 2020 09 18;14(9):11225-11237. Epub 2020 Aug 18.

Bio-Organic Chemistry, Institute for Complex Molecular Systems, Eindhoven University of Technology, 5600 MB Eindhoven, The Netherlands.

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September 2020

Acid-Activatable Transmorphic Peptide-Based Nanomaterials for Photodynamic Therapy.

Angew Chem Int Ed Engl 2020 11 2;59(46):20582-20588. Epub 2020 Sep 2.

Bio-Organic Chemistry, Institute of Complex Molecular Systems, Department of Biomedical Engineering, Eindhoven University of Technology, P. O. Box 513, 5600 MB, Eindhoven, The Netherlands.

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November 2020

Bone-Targeting Prodrug Mesoporous Silica-Based Nanoreactor with Reactive Oxygen Species Burst for Enhanced Chemotherapy.

ACS Appl Mater Interfaces 2020 Aug 21;12(31):34630-34642. Epub 2020 Jul 21.

School of Pharmaceutical Sciences, Guangdong Provincial Key Laboratory of New Drug Screening, Southern Medical University, Guangzhou 510515, China.

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August 2020

GE11 peptide-installed chimaeric polymersomes tailor-made for high-efficiency EGFR-targeted protein therapy of orthotopic hepatocellular carcinoma.

Acta Biomater 2020 09 18;113:512-521. Epub 2020 Jun 18.

Biomedical Polymers Laboratory, College of Chemistry, Chemical Engineering and Materials Science, and State Key Laboratory of Radiation Medicine and Protection, Soochow University, Soochow University, Suzhou, 215123, PR China. Electronic address:

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September 2020

Hyperthermia-Triggered On-Demand Biomimetic Nanocarriers for Synergetic Photothermal and Chemotherapy.

Adv Sci (Weinh) 2020 Jun 20;7(11):1903642. Epub 2020 Apr 20.

School of Pharmaceutical Science Guangdong Provincial Key Laboratory of New Drug Screening Southern Medical University Guangzhou 510515 China.

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June 2020

Photoactivated Polymersome Nanomotors: Traversing Biological Barriers.

Angew Chem Int Ed Engl 2020 09 27;59(39):16918-16925. Epub 2020 Jul 27.

Bio-Organic Chemistry, Institute of Complex Molecular Systems, Department of Biomedical Engineering, Eindhoven University of Technology, Helix (STO 3.41), P. O. Box 513, 5600 MB, Eindhoven, The Netherlands.

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September 2020

Nanoparticles based on natural, engineered or synthetic proteins and polypeptides for drug delivery applications.

Int J Pharm 2020 Aug 9;586:119537. Epub 2020 Jun 9.

Univ. Bordeaux, CNRS, Bordeaux INP, LCPO, UMR 5629, F-33600 Pessac, France. Electronic address:

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August 2020

Exploring the Impact of Morphology on the Properties of Biodegradable Nanoparticles and Their Diffusion in Complex Biological Medium.

Biomacromolecules 2021 Jan 26;22(1):126-133. Epub 2020 Jun 26.

Bio-Organic Chemistry, Institute for Complex Molecular Systems, Eindhoven University of Technology, P.O. Box 513 (STO 3.41), 5600 MB Eindhoven, The Netherlands.

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January 2021

Hybrid Biodegradable Nanomotors through Compartmentalized Synthesis.

Nano Lett 2020 06 22;20(6):4472-4480. Epub 2020 May 22.

Department of Bio-Organic Chemistry, Institute of Complex Molecular Systems (ICMS), Eindhoven University of Technology, Het Kranenveld 14, 5600 MB Eindhoven, The Netherlands.

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June 2020

Supramolecular Nanoscaffolds within Cytomimetic Protocells as Signal Localization Hubs.

J Am Chem Soc 2020 05 7;142(20):9106-9111. Epub 2020 May 7.

Laboratories of Chemical Biology and Bio-Organic Chemistry, Department of Biomedical Engineering and Institute for Complex Molecular Systems, Eindhoven University of Technology, P.O. Box 513, 5600MB Eindhoven, The Netherlands.

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May 2020

Multifunctional PVCL nanogels with redox-responsiveness enable enhanced MR imaging and ultrasound-promoted tumor chemotherapy.

Theranostics 2020 15;10(10):4349-4358. Epub 2020 Mar 15.

State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, International Joint Laboratory for Advanced Fiber and Low-dimension Materials, College of Chemistry, Chemical Engineering and Biotechnology, Donghua University, Shanghai 201620, People's Republic of China.

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March 2020

Synthetic pathways to tetrahydrocannabinol (THC): an overview.

Org Biomol Chem 2020 May;18(17):3203-3215

Institute for Molecules and Materials, Radboud University, Heyendaalseweg 135, 6525 AJ Nijmegen, The Netherlands.

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May 2020

Intercellular communication between artificial cells by allosteric amplification of a molecular signal.

Nat Commun 2020 04 3;11(1):1652. Epub 2020 Apr 3.

Department of Chemical Engineering and Chemistry, Eindhoven University of Technology, PO Box 513, 5600 MB, Eindhoven, the Netherlands.

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April 2020

Wormlike Nanovector with Enhanced Drug Loading Using Blends of Biodegradable Block Copolymers.

Biomacromolecules 2020 06 8;21(6):2199-2207. Epub 2020 Apr 8.

Department of Chemistry, College of Science, Swansea University, Swansea, United Kingdom.

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June 2020

αβ Integrin-Targeting Polymersomal Docetaxel as an Advanced Nanotherapeutic for Nonsmall Cell Lung Cancer Treatment.

ACS Appl Mater Interfaces 2020 Apr 18;12(13):14905-14913. Epub 2020 Mar 18.

Biomedical Polymers Laboratory, College of Chemistry, Chemical Engineering and Materials Science, and State Key Laboratory of Radiation Medicine and Protection, Soochow University, Suzhou 215123, P. R. China.

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April 2020