Publications by authors named "Jan Borén"

100Publications

Lack of RAC1 in macrophages protects against atherosclerosis.

PLoS One 2020 17;15(9):e0239284. Epub 2020 Sep 17.

Department of Laboratory Medicine, Institute of Biomedicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0239284PLOS
September 2020

Multimodal MALDI Imaging Mass Spectrometry Reveals Spatially Correlated Lipid and Protein Changes in Mouse Heart with Acute Myocardial Infarction.

J Am Soc Mass Spectrom 2020 Sep 21. Epub 2020 Sep 21.

Department of Chemistry and Molecular Biology, University of Gothenburg, 405 30 Gothenburg, Sweden.

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http://dx.doi.org/10.1021/jasms.0c00245DOI Listing
September 2020

The Roles of ApoC-III on the Metabolism of Triglyceride-Rich Lipoproteins in Humans.

Front Endocrinol (Lausanne) 2020 28;11:474. Epub 2020 Jul 28.

Research Programs Unit, Clinical and Molecular Metabolism, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.3389/fendo.2020.00474DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7399058PMC
July 2020

Lipid profiling of human diabetic myocardium reveals differences in triglyceride fatty acyl chain length and degree of saturation.

Int J Cardiol 2020 Jul 30. Epub 2020 Jul 30.

Department of Molecular and Clinical Medicine, Wallenberg Laboratory, Institute of Medicine, the Sahlgrenska Academy at University of Gothenburg and Sahlgrenska University Hospital, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2020.07.017DOI Listing
July 2020

Suppressed Vascular Leakage and Myocardial Edema Improve Outcome From Myocardial Infarction.

Front Physiol 2020 9;11:763. Epub 2020 Jul 9.

Beijer and Science for Life Laboratories, Department of Immunology, Genetics and Pathology, Rudbeck Laboratory, Uppsala University, Uppsala, Sweden.

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http://dx.doi.org/10.3389/fphys.2020.00763DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7363985PMC
July 2020

Systems Biology Approaches to Understand the Host-Microbiome Interactions in Neurodegenerative Diseases.

Front Neurosci 2020 8;14:716. Epub 2020 Jul 8.

Centre for Host-Microbiome Interactions, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, London, United Kingdom.

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http://dx.doi.org/10.3389/fnins.2020.00716DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7360858PMC
July 2020

Current Status of COVID-19 Therapies and Drug Repositioning Applications.

iScience 2020 Jul 20;23(7):101303. Epub 2020 Jun 20.

Science for Life Laboratory, KTH - Royal Institute of Technology, Stockholm 17121, Sweden; Centre for Host-Microbiome Interactions, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, London SE1 9RT, UK. Electronic address:

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http://dx.doi.org/10.1016/j.isci.2020.101303DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305759PMC
July 2020

Improvement in the Current Therapies for Hepatocellular Carcinoma Using a Systems Medicine Approach.

Adv Biosyst 2020 Jun 8;4(6):e2000030. Epub 2020 Apr 8.

Science for Life Laboratory, KTH - Royal Institute of Technology, Stockholm, SE 17121, Sweden.

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http://dx.doi.org/10.1002/adbi.202000030DOI Listing
June 2020

Causes and Consequences of Hypertriglyceridemia.

Front Endocrinol (Lausanne) 2020 14;11:252. Epub 2020 May 14.

Research Programs Unit, Clinical and Molecular Metabolism, University of Helsinki, Helsinki, Finland.

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http://dx.doi.org/10.3389/fendo.2020.00252DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7239992PMC
May 2020

A systems biology approach for studying neurodegenerative diseases.

Drug Discov Today 2020 Jul 19;25(7):1146-1159. Epub 2020 May 19.

Centre for Host-Microbiome Interactions, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, London, SE1 9RT, UK; Science for Life Laboratory, KTH - Royal Institute of Technology, Stockholm, SE-17121, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.drudis.2020.05.010DOI Listing
July 2020

The year 2019 in Atherosclerosis.

Atherosclerosis 2020 04 19;299:67-75. Epub 2020 Mar 19.

Institute of Clinical Chemistry, University of Zurich, University Hospital of Zurich, Zurich, Switzerland. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2020.03.018DOI Listing
April 2020

Addressing the heterogeneity in liver diseases using biological networks.

Brief Bioinform 2020 Mar 23. Epub 2020 Mar 23.

Centre for Host-Microbiome Interactions, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, London, SE1 9RT, United Kingdom; Science for Life Laboratory, KTH - Royal Institute of Technology, Stockholm, SE-17121, Sweden.

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http://dx.doi.org/10.1093/bib/bbaa002DOI Listing
March 2020

Impact of proprotein convertase subtilisin/kexin type 9 inhibition with evolocumab on the postprandial responses of triglyceride-rich lipoproteins in type II diabetic subjects.

J Clin Lipidol 2020 Jan - Feb;14(1):77-87. Epub 2019 Dec 12.

Department of Molecular and Clinical Medicine, Institute of Medicine, University of Gothenburg, Sweden; Wallenberg Laboratory, Sahlgrenska University Hospital, Gothenburg, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.jacl.2019.12.003DOI Listing
December 2019

Systems biology perspective for studying the gut microbiota in human physiology and liver diseases.

EBioMedicine 2019 Nov 18;49:364-373. Epub 2019 Oct 18.

Science for Life Laboratory, KTH - Royal Institute of Technology, Stockholm, Sweden; Centre for Host-Microbiome Interactions, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, London, SE1 9RT, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2019.09.057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6945237PMC
November 2019

Systems biology based drug repositioning for development of cancer therapy.

Semin Cancer Biol 2019 Sep 27. Epub 2019 Sep 27.

Science for Life Laboratory, KTH - Royal Institute of Technology, Stockholm SE-17121, Sweden; Centre for Host-Microbiome Interactions, Faculty of Dentistry, Oral & Craniofacial Sciences, King's College London, London SE1 9RT, United Kingdom. Electronic address:

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http://dx.doi.org/10.1016/j.semcancer.2019.09.020DOI Listing
September 2019

Cardiac expression of the microsomal triglyceride transport protein protects the heart function during ischemia.

J Mol Cell Cardiol 2019 12 15;137:1-8. Epub 2019 Sep 15.

Department of Molecular and Clinical Medicine, Wallenberg Laboratory, University of Gothenburg, Sahlgrenska University Hospital, Gothenburg, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.yjmcc.2019.09.003DOI Listing
December 2019

Dietary Fructose and the Metabolic Syndrome.

Nutrients 2019 Aug 22;11(9). Epub 2019 Aug 22.

Department of Molecular and Clinical Medicine, University of Gothenburg and Sahlgrenska University Hospital, 41345 Gothenburg, Sweden.

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http://dx.doi.org/10.3390/nu11091987DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6770027PMC
August 2019

The Potential Use of Metabolic Cofactors in Treatment of NAFLD.

Nutrients 2019 Jul 12;11(7). Epub 2019 Jul 12.

Department of Molecular and Clinical Medicine, University of Gothenburg and Sahlgrenska University Hospital Gothenburg, 41345 Gothenburg, Sweden.

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http://dx.doi.org/10.3390/nu11071578DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6682907PMC
July 2019

Protein kinase MST3 modulates lipid homeostasis in hepatocytes and correlates with nonalcoholic steatohepatitis in humans.

FASEB J 2019 09 7;33(9):9974-9989. Epub 2019 Jun 7.

Department of Chemistry and Molecular Biology, University of Gothenburg and Sahlgrenska University Hospital, Gothenburg, Sweden.

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http://dx.doi.org/10.1096/fj.201900356RRDOI Listing
September 2019

Emerging Evidence that ApoC-III Inhibitors Provide Novel Options to Reduce the Residual CVD.

Curr Atheroscler Rep 2019 05 20;21(8):27. Epub 2019 May 20.

Wallenberg Laboratory, Department of Molecular and Clinical Medicine, University of Gothenburg and Sahlgrenska University Hospital, Gothenburg, Sweden.

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http://dx.doi.org/10.1007/s11883-019-0791-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6527792PMC
May 2019

Plin2-deficiency reduces lipophagy and results in increased lipid accumulation in the heart.

Sci Rep 2019 05 6;9(1):6909. Epub 2019 May 6.

Department of Molecular and Clinical Medicine/Wallenberg Laboratory, Institute of Medicine, the Sahlgrenska Academy at University of Gothenburg and Sahlgrenska University Hospital, Gothenburg, Sweden.

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http://dx.doi.org/10.1038/s41598-019-43335-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6502866PMC
May 2019

Targeting Filamin A Reduces Macrophage Activity and Atherosclerosis.

Circulation 2019 07 24;140(1):67-79. Epub 2019 Apr 24.

Department of Medical Biochemistry and Cell Biology, Institute of Biomedicine (S.B., C.A., R.S., S.D., J.V.d.E., E.L., L.M.A.), Sahlgrenska Academy, University of Gothenburg, Sweden.

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https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.119.0
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http://dx.doi.org/10.1161/CIRCULATIONAHA.119.039697DOI Listing
July 2019

Vimentin is required for normal accumulation of body fat.

Biol Chem 2019 08;400(9):1157-1162

Laboratory of Astrocyte Biology and CNS Regeneration, Center for Brain Repair, Department of Clinical Neuroscience, Institute of Neuroscience and Physiology, Sahlgrenska Academy at the University of Gothenburg, Box 440, S-40530 Gothenburg, Sweden.

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http://www.degruyter.com/view/j/bchm.just-accepted/hsz-2019-
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http://dx.doi.org/10.1515/hsz-2019-0170DOI Listing
August 2019

Role of apolipoprotein C-III overproduction in diabetic dyslipidaemia.

Diabetes Obes Metab 2019 08 8;21(8):1861-1870. Epub 2019 May 8.

Department of Molecular and Clinical Medicine, University of Gothenburg, Sahlgrenska University Hospital, Gothenburg, Sweden.

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http://dx.doi.org/10.1111/dom.13744DOI Listing
August 2019

AdipoR1 and AdipoR2 maintain membrane fluidity in most human cell types and independently of adiponectin.

J Lipid Res 2019 05 19;60(5):995-1004. Epub 2019 Mar 19.

Department of Chemistry and Molecular Biology; University of Gothenburg, Gothenburg, Sweden

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http://dx.doi.org/10.1194/jlr.M092494DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6495173PMC
May 2019

Pyruvate kinase L/R is a regulator of lipid metabolism and mitochondrial function.

Metab Eng 2019 03 4;52:263-272. Epub 2019 Jan 4.

Science for Life Laboratory, KTH - Royal Institute of Technology, Stockholm, Sweden; Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden; Centre for Host-Microbiome Interactions, Dental Institute, King's College London, London SE1 9RT, United Kingdom. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10967176183031
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http://dx.doi.org/10.1016/j.ymben.2019.01.001DOI Listing
March 2019

Characterization of heterogeneous redox responses in hepatocellular carcinoma patients using network analysis.

EBioMedicine 2019 Feb 31;40:471-487. Epub 2018 Dec 31.

Science for Life Laboratory, KTH - Royal Institute of Technology, SE-171 21 Stockholm, Sweden; Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden; Centre for Host-Microbiome Interactions, Dental Institute, King's College London, London, UK. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2018.12.057DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412169PMC
February 2019

Disturbed Laminar Blood Flow Causes Impaired Fibrinolysis and Endothelial Fibrin Deposition In Vivo.

Thromb Haemost 2019 Feb 2;119(2):223-233. Epub 2019 Jan 2.

Wallenberg Laboratory, Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska University Hospital, University of Gothenburg, Gothenburg, Sweden.

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http://www.thieme-connect.de/DOI/DOI?10.1055/s-0038-1676638
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http://dx.doi.org/10.1055/s-0038-1676638DOI Listing
February 2019

Crosstalk between nonalcoholic fatty liver disease and cardiometabolic syndrome.

Obes Rev 2019 04 27;20(4):599-611. Epub 2018 Dec 27.

Department of Molecular and Clinical Medicine/Wallenberg Lab, University of Gothenburg and Sahlgrenska University Hospital, Gothenburg, Sweden.

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http://doi.wiley.com/10.1111/obr.12820
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http://dx.doi.org/10.1111/obr.12820DOI Listing
April 2019

Targeted Delivery of Stk25 Antisense Oligonucleotides to Hepatocytes Protects Mice Against Nonalcoholic Fatty Liver Disease.

Cell Mol Gastroenterol Hepatol 2019 19;7(3):597-618. Epub 2018 Dec 19.

Lundberg Laboratory for Diabetes Research, Department of Molecular and Clinical Medicine, Institute of Medicine, University of Gothenburg, Sahlgrenska University Hospital, Gothenburg, Sweden. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S2352345X183017
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http://dx.doi.org/10.1016/j.jcmgh.2018.12.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6411916PMC
June 2019

Metabolic network-based stratification of hepatocellular carcinoma reveals three distinct tumor subtypes.

Proc Natl Acad Sci U S A 2018 12 27;115(50):E11874-E11883. Epub 2018 Nov 27.

Science for Life Laboratory, KTH Royal Institute of Technology, SE-17121 Stockholm, Sweden;

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http://dx.doi.org/10.1073/pnas.1807305115DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6294939PMC
December 2018

Endothelial repair is dependent on CD11c leukocytes to establish regrowing endothelial sheets with high cellular density.

J Leukoc Biol 2019 01 28;105(1):195-202. Epub 2018 Sep 28.

Department of Molecular and Clinical Medicine, Wallenberg Laboratory, Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1002/JLB.4A1017-402RRDOI Listing
January 2019

Glucosylceramide modifies the LPS-induced inflammatory response in macrophages and the orientation of the LPS/TLR4 complex in silico.

Sci Rep 2018 09 11;8(1):13600. Epub 2018 Sep 11.

Institute of Medicine, Department of Molecular and Clinical Medicine/Wallenberg Laboratory, University of Gothenburg and Sahlgrenska University Hospital, Gothenburg, Sweden.

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http://dx.doi.org/10.1038/s41598-018-31926-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6134110PMC
September 2018

Impact of Gut Microbiota and Diet on the Development of Atherosclerosis in Apoe Mice.

Arterioscler Thromb Vasc Biol 2018 10;38(10):2318-2326

From the Department of Molecular and Clinical Medicine, Wallenberg Laboratory, Sahlgrenska University Hospital, University of Gothenburg, Sweden (A.L.J., R.C., R.A., C.R., F.F.H., J.B., F.B.).

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http://dx.doi.org/10.1161/ATVBAHA.118.311233DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6166703PMC
October 2018

Drug Repositioning for Effective Prostate Cancer Treatment.

Front Physiol 2018 15;9:500. Epub 2018 May 15.

Science for Life Laboratory, KTH Royal Institute of Technology, Stockholm, Sweden.

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http://dx.doi.org/10.3389/fphys.2018.00500DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5962745PMC
May 2018

STK25 regulates oxidative capacity and metabolic efficiency in adipose tissue.

J Endocrinol 2018 09 24;238(3):187-202. Epub 2018 May 24.

Lundberg Laboratory for Diabetes ResearchDepartment of Molecular and Clinical Medicine, Institute of Medicine, University of Gothenburg, Sahlgrenska University Hospital, Gothenburg, Sweden

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http://dx.doi.org/10.1530/JOE-18-0182DOI Listing
September 2018

Niacin action in the atherogenic mixed dyslipidemia of metabolic syndrome: Insights from metabolic biomarker profiling and network analysis.

J Clin Lipidol 2018 May - Jun;12(3):810-821.e1. Epub 2018 Mar 29.

Department of Molecular and Clinical Medicine and Wallenberg Laboratory, Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1016/j.jacl.2018.03.083DOI Listing
September 2019

Systems biology in hepatology: approaches and applications.

Nat Rev Gastroenterol Hepatol 2018 06;15(6):365-377

Science for Life Laboratory, KTH - Royal Institute of Technology, Stockholm, Sweden.

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http://dx.doi.org/10.1038/s41575-018-0007-8DOI Listing
June 2018

Sulfatide isoform pattern in cerebrospinal fluid discriminates progressive MS from relapsing-remitting MS.

J Neurochem 2018 08 3;146(3):322-332. Epub 2018 Jul 3.

Department of Clinical Chemistry and Transfusion Medicine, Institute of Biomedicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1111/jnc.14452DOI Listing
August 2018

Serine/threonine protein kinase 25 antisense oligonucleotide treatment reverses glucose intolerance, insulin resistance, and nonalcoholic fatty liver disease in mice.

Hepatol Commun 2018 01 20;2(1):69-83. Epub 2017 Nov 20.

Lundberg Laboratory for Diabetes Research, Department of Molecular and Clinical Medicine, Institute of Medicine University of Gothenburg, Sahlgrenska University Hospital Gothenburg Sweden.

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http://dx.doi.org/10.1002/hep4.1128DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5776874PMC
January 2018

Broad Views of Non-alcoholic Fatty Liver Disease.

Cell Syst 2018 01;6(1):7-9

Department of Molecular and Clinical Medicine/Wallenberg Laboratory, University of Gothenburg, and Sahlgrenska University Hospital, Gothenburg, Sweden.

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http://dx.doi.org/10.1016/j.cels.2018.01.004DOI Listing
January 2018

Elevated Plasma Levels of 3-Hydroxyisobutyric Acid Are Associated With Incident Type 2 Diabetes.

EBioMedicine 2018 Jan 7;27:151-155. Epub 2017 Dec 7.

Department of Molecular and Clinical Medicine, University of Gothenburg, Sahlgrenska University Hospital, Gothenburg, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.ebiom.2017.12.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5828558PMC
January 2018

The adiponectin receptor AdipoR2 and its Caenorhabditis elegans homolog PAQR-2 prevent membrane rigidification by exogenous saturated fatty acids.

PLoS Genet 2017 Sep 8;13(9):e1007004. Epub 2017 Sep 8.

Department of Chemistry and Molecular Biology, University of Gothenburg, Gothenburg, Sweden.

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http://dx.doi.org/10.1371/journal.pgen.1007004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5607217PMC
September 2017

Deficiency in perilipin 5 reduces mitochondrial function and membrane depolarization in mouse hearts.

Int J Biochem Cell Biol 2017 10 12;91(Pt A):9-13. Epub 2017 Aug 12.

Department of Molecular and Clinical Medicine/Wallenberg Laboratory, Institute of Medicine, University of Gothenburg and Sahlgrenska University Hospital, Gothenburg, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.biocel.2017.07.021DOI Listing
October 2017

Family-specific aggregation of lipid GWAS variants confers the susceptibility to familial hypercholesterolemia in a large Austrian family.

Atherosclerosis 2017 Sep 22;264:58-66. Epub 2017 Jul 22.

Department of Human Genetics, David Geffen School of Medicine at UCLA, Los Angeles, USA; Molecular Biology Institute at UCLA, Los Angeles, USA; Bioinformatics Interdepartmental Program, UCLA, Los Angeles, CA, USA. Electronic address:

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http://dx.doi.org/10.1016/j.atherosclerosis.2017.07.024DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5698088PMC
September 2017

Plasma Mannose Levels Are Associated with Incident Type 2 Diabetes and Cardiovascular Disease.

Cell Metab 2017 Aug;26(2):281-283

Department of Molecular and Clinical Medicine, University of Gothenburg and Sahlgrenska University Hospital, Gothenburg 41345, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2017.07.006DOI Listing
August 2017

Improving the economics of NASH/NAFLD treatment through the use of systems biology.

Drug Discov Today 2017 10 20;22(10):1532-1538. Epub 2017 Jul 20.

Science for Life Laboratory, KTH - Royal Institute of Technology, SE-171 21, Stockholm, Sweden; Department of Biology and Biological Engineering, Chalmers University of Technology, SE-412 96, Gothenburg, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.drudis.2017.07.005DOI Listing
October 2017

Intimal hyperplasia induced by vascular intervention causes lipoprotein retention and accelerated atherosclerosis.

Physiol Rep 2017 Jul;5(14)

Department of Molecular and Clinical Medicine, Wallenberg Laboratory, Institute of Medicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden

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http://dx.doi.org/10.14814/phy2.13334DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5532481PMC
July 2017

Depletion of ATP and glucose in advanced human atherosclerotic plaques.

PLoS One 2017 1;12(6):e0178877. Epub 2017 Jun 1.

Department of Molecular and Clinical Medicine, Wallenberg Laboratory, University of Gothenburg and Sahlgrenska University Hospital, Gothenburg, Sweden.

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0178877PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5453577PMC
September 2017

High-throughput analysis of sulfatides in cerebrospinal fluid using automated extraction and UPLC-MS/MS.

J Lipid Res 2017 07 26;58(7):1482-1489. Epub 2017 May 26.

Department of Molecular and Clinical Medicine, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden

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http://dx.doi.org/10.1194/jlr.D076588DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5496026PMC
July 2017

AUP1 (Ancient Ubiquitous Protein 1): A Molecular Link Between Hepatic Lipid Mobilization and VLDL Secretion.

Arterioscler Thromb Vasc Biol 2017 04;37(4):609-610

From the Department of Biology and Biological Engineering, Chalmers University of Technology, Gothenburg, Sweden (A.M.); Science for Life Laboratory, KTH, Royal Institute of Technology, Stockholm, Sweden (A.M.); and Department of Molecular and Clinical Medicine, University of Gothenburg and Sahlgrenska University Hospital, Sweden (J.B.).

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http://dx.doi.org/10.1161/ATVBAHA.117.309152DOI Listing
April 2017

Overexpression of protein kinase STK25 in mice exacerbates ectopic lipid accumulation, mitochondrial dysfunction and insulin resistance in skeletal muscle.

Diabetologia 2017 03 16;60(3):553-567. Epub 2016 Dec 16.

Lundberg Laboratory for Diabetes Research, Department of Molecular and Clinical Medicine, University of Gothenburg, Sahlgrenska University Hospital, Blå stråket 5, SE-41345, Gothenburg, Sweden.

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http://dx.doi.org/10.1007/s00125-016-4171-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6518105PMC
March 2017

Kinetics of plasma triglycerides in abdominal obesity.

Curr Opin Lipidol 2017 02;28(1):11-18

aDepartment of Molecular and Clinical Medicine, University of Gothenburg and Sahlgrenska University Hospital, Gothenburg, Sweden bResearch Programs Unit, Diabetes and Obesity, University of Helsinki and Heart and Lung Center, Helsinki University Hospital, Helsinki, Finland.

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http://dx.doi.org/10.1097/MOL.0000000000000375DOI Listing
February 2017

Why Is Apolipoprotein CIII Emerging as a Novel Therapeutic Target to Reduce the Burden of Cardiovascular Disease?

Curr Atheroscler Rep 2016 10;18(10):59

Department of Molecular and Clinical Medicine, University of Gothenburg and Sahlgrenska University Hospital, Gothenburg, Sweden.

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http://dx.doi.org/10.1007/s11883-016-0614-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5018018PMC
October 2016

ARAP2 promotes GLUT1-mediated basal glucose uptake through regulation of sphingolipid metabolism.

Biochim Biophys Acta 2016 11 27;1861(11):1643-1651. Epub 2016 Jul 27.

Department of Molecular and Clinical Medicine, University of Gothenburg, Sweden; Sahlgrenska University Hospital, Gothenburg, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.bbalip.2016.07.009DOI Listing
November 2016

The central role of arterial retention of cholesterol-rich apolipoprotein-B-containing lipoproteins in the pathogenesis of atherosclerosis: a triumph of simplicity.

Curr Opin Lipidol 2016 10;27(5):473-83

aDepartment of Molecular and Clinical Medicine, University of Gothenburg bSahlgrenska University Hospital, Gothenburg, Sweden cSection of Endocrinology, Diabetes, & Metabolism, Department of Medicine, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania, USA.

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http://dx.doi.org/10.1097/MOL.0000000000000330DOI Listing
October 2016

Triglyceride-rich lipoprotein metabolism in women: roles of apoC-II and apoC-III.

Eur J Clin Invest 2016 Aug;46(8):730-6

Metabolic Research Centre, School of Medicine and Pharmacology, University of Western Australia, Crawley, WA, Australia.

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http://dx.doi.org/10.1111/eci.12657DOI Listing
August 2016

Perilipin 5 is protective in the ischemic heart.

Int J Cardiol 2016 Sep 16;219:446-54. Epub 2016 Jun 16.

Department of Molecular and Clinical Medicine, Institute of Medicine, University of Gothenburg and Sahlgrenska University Hospital, Gothenburg, Sweden; Wallenberg Laboratory, Institute of Medicine, University of Gothenburg and Sahlgrenska University Hospital, Gothenburg, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.ijcard.2016.06.037DOI Listing
September 2016

Integrated Network Analysis Reveals an Association between Plasma Mannose Levels and Insulin Resistance.

Cell Metab 2016 07 23;24(1):172-84. Epub 2016 Jun 23.

Science for Life Laboratory, KTH-Royal Institute of Technology, 171 21 Stockholm, Sweden; Department of Biology and Biological Engineering, Chalmers University of Technology, 412 96 Gothenburg, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.cmet.2016.05.026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6666317PMC
July 2016

Microdialysis and proteomics of subcutaneous interstitial fluid reveals increased galectin-1 in type 2 diabetes patients.

Metabolism 2016 07 13;65(7):998-1006. Epub 2016 Apr 13.

Department of Molecular and Clinical Medicine, Wallenberg Laboratory, Institute of Medicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden. Electronic address:

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http://dx.doi.org/10.1016/j.metabol.2016.04.003DOI Listing
July 2016

Triglyceride-Rich Lipoproteins and Remnants: Targets for Therapy?

Curr Cardiol Rep 2016 07;18(7):67

INSERM and University of Pierre and Marie Curie, Pitie-Salpetriere University Hospital, 75651, Paris Cedex 13, France.

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http://dx.doi.org/10.1007/s11886-016-0745-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4877422PMC
July 2016

Sphingolipids Contribute to Human Atherosclerotic Plaque Inflammation.

Arterioscler Thromb Vasc Biol 2016 06 7;36(6):1132-40. Epub 2016 Apr 7.

From the Experimental Cardiovascular Research Unit, Clinical Research Centre, Clinical Sciences Malmö, Lund University, Malmö, Sweden (A.E., P.D., G.A., H.G., M.N., A.F.P., J.N., I.G.); Vascular Centre Malmö-Lund, Skåne, University Hospital, Malmö, Sweden (G.A.); Department of Cardiology, Skåne University Hospital, Lund/Malmö, Sweden (A.E., H.G., A.F.P., I.G.); Department of Molecular and Clinical Medicine/Wallenberg Laboratory, Sahlgrenska University Hospital University, Gothenburg, Sweden (M.S., J.B.); Cardiovascular Medicine Unit, Department of Medicine Solna, Karolinska Institutet, Solna, Sweden (R.M.F.); and Department of Clinical Sciences Malmö, Clinical Research Center, Lund University, Malmö, Sweden (I.G.M., O.M., M.O.-M.).

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http://dx.doi.org/10.1161/ATVBAHA.116.305675DOI Listing
June 2016