Publications by authors named "Jamie Rossjohn"

100Publications

Human γδ T cells recognize CD1b by two distinct mechanisms.

Proc Natl Acad Sci U S A 2020 Sep 31;117(37):22944-22952. Epub 2020 Aug 31.

Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Boston, MA 02115;

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http://dx.doi.org/10.1073/pnas.2010545117DOI Listing
September 2020

Overlapping Peptides Elicit Distinct CD8 T Cell Responses following Influenza A Virus Infection.

J Immunol 2020 Aug 31. Epub 2020 Aug 31.

Department of Biochemistry and Molecular Biology, Monash Biomedicine Discovery Institute, Monash University, Clayton, Victoria 3800, Australia;

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http://dx.doi.org/10.4049/jimmunol.2000689DOI Listing
August 2020

A Shared TCR Bias toward an Immunogenic EBV Epitope Dominates in HLA-B*07:02-Expressing Individuals.

J Immunol 2020 Sep 19;205(6):1524-1534. Epub 2020 Aug 19.

Department of Medicine, Monash University, Central Clinical School, The Alfred Hospital, Melbourne, Victoria 3004, Australia;

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http://dx.doi.org/10.4049/jimmunol.2000249DOI Listing
September 2020

Tetramer Immunization and Selection Followed by CELLISA Screening to Generate Monoclonal Antibodies against the Mouse Cytomegalovirus m12 Immunoevasin.

J Immunol 2020 Sep 19;205(6):1709-1717. Epub 2020 Aug 19.

Department of Immunology, University of Toronto, Toronto, Ontario M5S 1A8, Canada;

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http://dx.doi.org/10.4049/jimmunol.2000687DOI Listing
September 2020

HLA-B*27:05 alters immunodominance hierarchy of universal influenza-specific CD8+ T cells.

PLoS Pathog 2020 08 4;16(8):e1008714. Epub 2020 Aug 4.

Department of Microbiology and Immunology, University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Parkville, Victoria, Australia.

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http://dx.doi.org/10.1371/journal.ppat.1008714DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7428290PMC
August 2020

Crystal Structure of the SARS-CoV-2 Non-structural Protein 9, Nsp9.

iScience 2020 Jul 9;23(7):101258. Epub 2020 Jun 9.

Infection and Immunity Program, Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, Australia; Australian Research Council Centre of Excellence for Advanced Molecular Imaging, Monash University, Clayton, VIC, Australia; Institute of Infection and Immunity, Cardiff University School of Medicine, Heath Park, Cardiff, UK. Electronic address:

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http://dx.doi.org/10.1016/j.isci.2020.101258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7282741PMC
July 2020

The molecular basis of how buried human leukocyte antigen polymorphism modulates natural killer cell function.

Proc Natl Acad Sci U S A 2020 05 13;117(21):11636-11647. Epub 2020 May 13.

Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, The University of Melbourne, Melbourne, VIC 3010, Australia;

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http://dx.doi.org/10.1073/pnas.1920570117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7261055PMC
May 2020

Ligand-dependent downregulation of MR1 cell surface expression.

Proc Natl Acad Sci U S A 2020 05 27;117(19):10465-10475. Epub 2020 Apr 27.

MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, University of Oxford, Oxford OX3 9DS, United Kingdom.

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http://dx.doi.org/10.1073/pnas.2003136117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229755PMC
May 2020

Challenges, Progress, and Prospects of Developing Therapies to Treat Autoimmune Diseases.

Cell 2020 Apr;181(1):63-80

Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia; Australian Research Council Centre of Excellence in Advanced Molecular Imaging, Monash University, Clayton, VIC 3800, Australia; Institute of Infection and Immunity, Cardiff University, School of Medicine, Heath Park, Cardiff CF14 4XN, UK. Electronic address:

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http://dx.doi.org/10.1016/j.cell.2020.03.007DOI Listing
April 2020

Preferential HLA-B27 Allorecognition Displayed by Multiple Cross-Reactive Antiviral CD8 T Cell Receptors.

Front Immunol 2020 19;11:248. Epub 2020 Feb 19.

Respiratory Medicine Laboratory, Department of Medicine, Central Clinical School, Monash University, Melbourne, VIC, Australia.

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http://dx.doi.org/10.3389/fimmu.2020.00248DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7042382PMC
February 2020

Virus-Mediated Suppression of the Antigen Presentation Molecule MR1.

Cell Rep 2020 Mar;30(9):2948-2962.e4

Discipline of Infectious Diseases and Immunology, Faculty of Medicine and Health, Charles Perkins Centre, University of Sydney, Sydney, NSW, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2020.02.017DOI Listing
March 2020

The molecular basis underpinning the potency and specificity of MAIT cell antigens.

Nat Immunol 2020 04 2;21(4):400-411. Epub 2020 Mar 2.

Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia.

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http://dx.doi.org/10.1038/s41590-020-0616-6DOI Listing
April 2020

A molecular basis for the T cell response in HLA-DQ2.2 mediated celiac disease.

Proc Natl Acad Sci U S A 2020 02 23;117(6):3063-3073. Epub 2020 Jan 23.

Infection and Immunity Program, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia;

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http://dx.doi.org/10.1073/pnas.1914308117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7022145PMC
February 2020

Cross-Reactive Donor-Specific CD8 Tregs Efficiently Prevent Transplant Rejection.

Cell Rep 2019 12;29(13):4245-4255.e6

Nantes Université, INSERM, Centre de Recherche en Transplantation et Immunologie, UMR 1064, ITUN, 44000 Nantes, France; LabEx IGO "Immunotherapy, Graft, Oncology," Nantes, France. Electronic address:

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http://dx.doi.org/10.1016/j.celrep.2019.11.106DOI Listing
December 2019

T cell receptor cross-reactivity between gliadin and bacterial peptides in celiac disease.

Nat Struct Mol Biol 2020 01 23;27(1):49-61. Epub 2019 Dec 23.

Infection and Immunity Program and The Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute Monash University, Clayton, Victoria, Australia.

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http://dx.doi.org/10.1038/s41594-019-0353-4DOI Listing
January 2020

Characterization of Human Mucosal-associated Invariant T (MAIT) Cells.

Curr Protoc Immunol 2019 12;127(1):e90

Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Australia.

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http://dx.doi.org/10.1002/cpim.90DOI Listing
December 2019

Characterization and Purification of Mouse Mucosal-Associated Invariant T (MAIT) Cells.

Curr Protoc Immunol 2019 12;127(1):e89

Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia.

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http://dx.doi.org/10.1002/cpim.89DOI Listing
December 2019

Distinct CD1d docking strategies exhibited by diverse Type II NKT cell receptors.

Nat Commun 2019 11 20;10(1):5242. Epub 2019 Nov 20.

Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, 3800, Australia.

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http://dx.doi.org/10.1038/s41467-019-12941-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6868179PMC
November 2019

Allelic association with ankylosing spondylitis fails to correlate with human leukocyte antigen B27 homodimer formation.

J Biol Chem 2019 12 18;294(52):20185-20195. Epub 2019 Nov 18.

Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria 3800, Australia

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http://dx.doi.org/10.1074/jbc.RA119.010257DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6937573PMC
December 2019

Modulation of innate and adaptive immunity by cytomegaloviruses.

Nat Rev Immunol 2020 02 30;20(2):113-127. Epub 2019 Oct 30.

Infection and Immunity Program, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia.

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http://dx.doi.org/10.1038/s41577-019-0225-5DOI Listing
February 2020

A subset of HLA-DP molecules serve as ligands for the natural cytotoxicity receptor NKp44.

Nat Immunol 2019 09 29;20(9):1129-1137. Epub 2019 Jul 29.

Research Department Virus Immunology, Heinrich Pette Institute, Leibniz Institute for Experimental Virology, Hamburg, Germany.

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http://dx.doi.org/10.1038/s41590-019-0448-4DOI Listing
September 2019

Structural basis for the recognition of nectin-like protein-5 by the human-activating immune receptor, DNAM-1.

J Biol Chem 2019 08 28;294(33):12534-12546. Epub 2019 Jun 28.

Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria 3800, Australia

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http://dx.doi.org/10.1074/jbc.RA119.009261DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6699837PMC
August 2019

A comprehensive review and performance evaluation of bioinformatics tools for HLA class I peptide-binding prediction.

Brief Bioinform 2020 Jul;21(4):1119-1135

Biomedicine Discovery Institute and Department of Biochemistry & Molecular Biology, Monash University, Melbourne, VIC, Australia.

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http://dx.doi.org/10.1093/bib/bbz051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7373177PMC
July 2020

Broad CD8 T cell cross-recognition of distinct influenza A strains in humans.

Nat Commun 2018 12 21;9(1):5427. Epub 2018 Dec 21.

Department of Microbiology and Immunology, The University of Melbourne, at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, 3010, Australia.

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http://www.nature.com/articles/s41467-018-07815-5
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http://dx.doi.org/10.1038/s41467-018-07815-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6303473PMC
December 2018

Structural Basis for CD96 Immune Receptor Recognition of Nectin-like Protein-5, CD155.

Structure 2019 02 6;27(2):219-228.e3. Epub 2018 Dec 6.

Infection and Immunity Program and The Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC 3800, Australia; Australian Research Council Centre of Excellence in Advanced Molecular Imaging, Monash University, Clayton, VIC 3800, Australia. Electronic address:

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http://dx.doi.org/10.1016/j.str.2018.10.023DOI Listing
February 2019

Discriminative T-cell receptor recognition of highly homologous HLA-DQ2-bound gluten epitopes.

J Biol Chem 2019 01 19;294(3):941-952. Epub 2018 Nov 19.

From the Department of Immunology, University of Oslo and Oslo University Hospital-Rikshospitalet, 0372 Oslo, Norway,

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http://dx.doi.org/10.1074/jbc.RA118.005736DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6341401PMC
January 2019

HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome.

Nat Commun 2018 11 8;9(1):4693. Epub 2018 Nov 8.

Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Monash Biomedicine Discovery Institute, Monash University, Clayton, VIC, 3800, Australia.

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http://www.nature.com/articles/s41467-018-07109-w
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http://dx.doi.org/10.1038/s41467-018-07109-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6224591PMC
November 2018

Recognition of host Clr-b by the inhibitory NKR-P1B receptor provides a basis for missing-self recognition.

Nat Commun 2018 11 5;9(1):4623. Epub 2018 Nov 5.

Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, 3800, Australia.

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http://www.nature.com/articles/s41467-018-06989-2
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http://dx.doi.org/10.1038/s41467-018-06989-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6218473PMC
November 2018

The Diverse Family of MR1-Restricted T Cells.

J Immunol 2018 11;201(10):2862-2871

Department of Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne, Victoria 3000, Australia;

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http://dx.doi.org/10.4049/jimmunol.1801091DOI Listing
November 2018

A subset of HLA-I peptides are not genomically templated: Evidence for cis- and trans-spliced peptide ligands.

Sci Immunol 2018 10;3(28)

Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria 3800, Australia.

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http://immunology.sciencemag.org/lookup/doi/10.1126/sciimmun
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http://dx.doi.org/10.1126/sciimmunol.aar3947DOI Listing
October 2018

HLA and kidney disease: from associations to mechanisms.

Nat Rev Nephrol 2018 10;14(10):636-655

Centre for Inflammatory Diseases, Monash University Department of Medicine, Monash Medical Centre, Clayton, Victoria, Australia.

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http://www.nature.com/articles/s41581-018-0057-8
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http://dx.doi.org/10.1038/s41581-018-0057-8DOI Listing
October 2018

CD4 T cell-mediated HLA class II cross-restriction in HIV controllers.

Sci Immunol 2018 06;3(24)

Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria 3800, Australia.

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http://dx.doi.org/10.1126/sciimmunol.aat0687DOI Listing
June 2018

Lipids hide or step aside for CD1-autoreactive T cell receptors.

Curr Opin Immunol 2018 06 5;52:93-99. Epub 2018 May 5.

Department of Medicine, Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, 60 Fenwood Road, Boston, MA 02115, USA. Electronic address:

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http://dx.doi.org/10.1016/j.coi.2018.04.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6004262PMC
June 2018

Inability To Detect Cross-Reactive Memory T Cells Challenges the Frequency of Heterologous Immunity among Common Viruses.

J Immunol 2018 06 7;200(12):3993-4003. Epub 2018 May 7.

Department of Medicine, Monash University, Central Clinical School, The Alfred Hospital, Melbourne, Victoria 3004, Australia;

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http://dx.doi.org/10.4049/jimmunol.1800010DOI Listing
June 2018

Reply to Roudier .: HLA-DRB1 polymorphism, anti-citrullinated protein antibodies, and rheumatoid arthritis.

J Biol Chem 2018 05;293(18):7039

From the Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria 3800, Australia

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http://www.jbc.org/lookup/doi/10.1074/jbc.RL118.003013
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http://dx.doi.org/10.1074/jbc.RL118.003013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5936809PMC
May 2018

Phospholipid signaling in innate immune cells.

J Clin Invest 2018 07 23;128(7):2670-2679. Epub 2018 Apr 23.

Babraham Institute, Babraham Research Campus, Cambridge, United Kingdom.

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http://dx.doi.org/10.1172/JCI97944DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026006PMC
July 2018

An overview on the identification of MAIT cell antigens.

Immunol Cell Biol 2018 07 15;96(6):573-587. Epub 2018 May 15.

Department of Microbiology and Immunology, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, VIC, 3000, Australia.

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http://dx.doi.org/10.1111/imcb.12057DOI Listing
July 2018

Understanding the drivers of MHC restriction of T cell receptors.

Nat Rev Immunol 2018 07;18(7):467-478

Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia.

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http://dx.doi.org/10.1038/s41577-018-0007-5DOI Listing
July 2018

Unconventional T Cell Targets for Cancer Immunotherapy.

Immunity 2018 03;48(3):453-473

Infection and Immunity Program and The Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria 3800, Australia; ARC Centre of Excellence in Advanced Molecular Imaging, Monash University, Clayton, Victoria 3800, Australia; Institute of Infection and Immunity, Cardiff University, School of Medicine, Heath Park, Cardiff CF14 4XN, UK. Electronic address:

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https://linkinghub.elsevier.com/retrieve/pii/S10747613183008
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http://dx.doi.org/10.1016/j.immuni.2018.03.009DOI Listing
March 2018

Divergent T-cell receptor recognition modes of a HLA-I restricted extended tumour-associated peptide.

Nat Commun 2018 03 12;9(1):1026. Epub 2018 Mar 12.

Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, 3800, Australia.

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http://dx.doi.org/10.1038/s41467-018-03321-wDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5847591PMC
March 2018

Identification of Native and Posttranslationally Modified HLA-B*57:01-Restricted HIV Envelope Derived Epitopes Using Immunoproteomics.

Proteomics 2018 06 10;18(12):e1700253. Epub 2018 Apr 10.

Infection and Immunity Program, Biomedicine Discovery Institute & Department of Biochemistry and Molecular Biology, Monash University, Clayton, Australia.

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http://dx.doi.org/10.1002/pmic.201700253DOI Listing
June 2018

Editorial.

Semin Cell Dev Biol 2018 12 28;84. Epub 2018 Feb 28.

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http://dx.doi.org/10.1016/j.semcdb.2018.02.008DOI Listing
December 2018

Flow Cytometric Clinical Immunomonitoring Using Peptide-MHC Class II Tetramers: Optimization of Methods and Protocol Development.

Front Immunol 2018 22;9. Epub 2018 Jan 22.

University of Queensland Diamantina Institute, Translational Research Institute, Princess Alexandra Hospital, Brisbane, QLD, Australia.

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http://journal.frontiersin.org/article/10.3389/fimmu.2018.00
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http://dx.doi.org/10.3389/fimmu.2018.00008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5786526PMC
February 2019

Mucosal-associated invariant T cell receptor recognition of small molecules presented by MR1.

Immunol Cell Biol 2018 07 27;96(6):588-597. Epub 2018 Feb 27.

Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, VIC, 3800, Australia.

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http://dx.doi.org/10.1111/imcb.12017DOI Listing
July 2018

The interplay between citrullination and HLA-DRB1 polymorphism in shaping peptide binding hierarchies in rheumatoid arthritis.

J Biol Chem 2018 03 9;293(9):3236-3251. Epub 2018 Jan 9.

From the Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute Monash University, and

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http://dx.doi.org/10.1074/jbc.RA117.001013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5836122PMC
March 2018

HLA variation and disease.

Nat Rev Immunol 2018 05 2;18(5):325-339. Epub 2018 Jan 2.

Danish National Research Foundation Centre PERSIMUNE, Rigshospitalet, University of Copenhagen, Copenhagen DK-2100, Denmark.

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http://www.nature.com/doifinder/10.1038/nri.2017.143
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http://dx.doi.org/10.1038/nri.2017.143DOI Listing
May 2018

A T Cell Receptor Locus Harbors a Malaria-Specific Immune Response Gene.

Immunity 2017 11 14;47(5):835-847.e4. Epub 2017 Nov 14.

Department of Microbiology, University of Iowa, Iowa City, IA 52242, USA; Department of Pathology, University of Iowa, Iowa City, IA 52242, USA; Interdisciplinary Program in Immunology, University of Iowa, Iowa City, IA 52242, USA. Electronic address:

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http://dx.doi.org/10.1016/j.immuni.2017.10.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724374PMC
November 2017

A molecular basis of human T cell receptor autoreactivity toward self-phospholipids.

Sci Immunol 2017 10;2(16)

Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria 3800, Australia.

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http://dx.doi.org/10.1126/sciimmunol.aao1384DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6649662PMC
October 2017

A conserved energetic footprint underpins recognition of human leukocyte antigen-E by two distinct αβ T cell receptors.

J Biol Chem 2017 12 25;292(51):21149-21158. Epub 2017 Sep 25.

From the Department of Microbiology and Immunology and Peter Doherty Institute for Infection and Immunity, University of Melbourne, Melbourne 3000, Australia,

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http://dx.doi.org/10.1074/jbc.M117.807719DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5743087PMC
December 2017

The molecular basis for peptide repertoire selection in the human leucocyte antigen (HLA) C*06:02 molecule.

J Biol Chem 2017 10 30;292(42):17203-17215. Epub 2017 Aug 30.

From the Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton 3800, Victoria, Australia,

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http://dx.doi.org/10.1074/jbc.M117.806976DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5655500PMC
October 2017

Structural determination of lipid antigens captured at the CD1d-T-cell receptor interface.

Proc Natl Acad Sci U S A 2017 08 17;114(31):8348-8353. Epub 2017 Jul 17.

Department of Medicine, Division of Rheumatology, Immunology, and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA 02115;

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http://dx.doi.org/10.1073/pnas.1705882114DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5547638PMC
August 2017

Structure-function analyses of a pertussis-like toxin from pathogenic reveal a distinct mechanism of inhibition of trimeric G-proteins.

J Biol Chem 2017 09 29;292(36):15143-15158. Epub 2017 Jun 29.

the Department of Animal, Plant and Soil Science and Centre for AgriBioscience, La Trobe University, Bundoora, Victoria 3086, Australia

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http://dx.doi.org/10.1074/jbc.M117.796094DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5592689PMC
September 2017

Structural and regulatory diversity shape HLA-C protein expression levels.

Nat Commun 2017 06 26;8:15924. Epub 2017 Jun 26.

MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DS, UK.

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http://dx.doi.org/10.1038/ncomms15924DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5490200PMC
June 2017

Recognition of nectin-2 by the natural killer cell receptor T cell immunoglobulin and ITIM domain (TIGIT).

J Biol Chem 2017 07 17;292(27):11413-11422. Epub 2017 May 17.

From the Infection and Immunity Program, Biomedicine Discovery Institute and

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http://www.jbc.org/lookup/doi/10.1074/jbc.M117.786483
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http://dx.doi.org/10.1074/jbc.M117.786483DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5500806PMC
July 2017

MAIT cells and MR1-antigen recognition.

Curr Opin Immunol 2017 Jun 8;46:66-74. Epub 2017 May 8.

Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria 3800, Australia; ARC Centre of Excellence in Advanced Molecular Imaging, Monash University, Clayton, Victoria 3800, Australia; Institute of Infection and Immunity, Cardiff University School of Medicine, Heath Park, Cardiff CF14 4XN, UK. Electronic address:

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http://dx.doi.org/10.1016/j.coi.2017.04.002DOI Listing
June 2017

A hot spot on interferon α/β receptor subunit 1 (IFNAR1) underpins its interaction with interferon-β and dictates signaling.

J Biol Chem 2017 05 13;292(18):7554-7565. Epub 2017 Mar 13.

From the Centre for Innate Immunity and Infectious Diseases, Hudson Institute of Medical Research, 27-31 Wright Street, Clayton, Victoria 3168, Australia,

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http://dx.doi.org/10.1074/jbc.M116.773788DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5418053PMC
May 2017

Circulating gluten-specific FOXP3CD39 regulatory T cells have impaired suppressive function in patients with celiac disease.

J Allergy Clin Immunol 2017 Dec 8;140(6):1592-1603.e8. Epub 2017 Mar 8.

Immunovirology and Pathogenesis Program, The Kirby Institute, UNSW Sydney, Sydney, Australia; St Vincent's Centre for Applied Medical Research, St Vincent's Hospital, Sydney, Australia.

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http://dx.doi.org/10.1016/j.jaci.2017.02.015DOI Listing
December 2017

Stabilizing short-lived Schiff base derivatives of 5-aminouracils that activate mucosal-associated invariant T cells.

Nat Commun 2017 03 8;8:14599. Epub 2017 Mar 8.

Division of Chemistry and Structural Biology, Institute for Molecular Bioscience, The University of Queensland, Brisbane, Queensland 4072, Australia.

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http://dx.doi.org/10.1038/ncomms14599DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5344979PMC
March 2017

MHC-I peptides get out of the groove and enable a novel mechanism of HIV-1 escape.

Nat Struct Mol Biol 2017 04 20;24(4):387-394. Epub 2017 Feb 20.

Infection and Immunity Program and Department of Biochemistry and Molecular Biology, Biomedicine Discovery Institute, Monash University, Clayton, Victoria, Australia.

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http://dx.doi.org/10.1038/nsmb.3381DOI Listing
April 2017