James Y Dai

James Y Dai

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James Y Dai

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Interactive decision support for esophageal adenocarcinoma screening and surveillance.

BMC Gastroenterol 2019 Jun 27;19(1):109. Epub 2019 Jun 27.

Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, 98109, USA.

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http://dx.doi.org/10.1186/s12876-019-1022-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6598240PMC
June 2019

Vigorous Physical Activity Is Associated with Lower Risk of Metastatic-Lethal Progression in Prostate Cancer and Hypomethylation in the Gene.

Cancer Epidemiol Biomarkers Prev 2019 Feb 21;28(2):258-264. Epub 2018 Nov 21.

Division of Public Health Sciences, Fred Hutchison Cancer Research Center, Seattle, Washington.

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http://dx.doi.org/10.1158/1055-9965.EPI-18-0622DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363836PMC
February 2019

Case-only Methods Identified Genetic Loci Predicting a Subgroup of Men with Reduced Risk of High-grade Prostate Cancer by Finasteride.

Cancer Prev Res (Phila) 2019 Feb 11;12(2):113-120. Epub 2018 Dec 11.

Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington.

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http://dx.doi.org/10.1158/1940-6207.CAPR-18-0284DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365187PMC
February 2019

Identifying disease-associated copy number variations by a doubly penalized regression model.

Biometrics 2018 12 12;74(4):1341-1350. Epub 2018 Jun 12.

Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, U.S.A.

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http://dx.doi.org/10.1111/biom.12920DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6663092PMC
December 2018

Case-only approach to identifying markers predicting treatment effects on the relative risk scale.

Biometrics 2018 06 28;74(2):753-763. Epub 2017 Sep 28.

Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, U.S.A.

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http://dx.doi.org/10.1111/biom.12789DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5874156PMC
June 2018

Editorial: Mendelian Randomization Analysis Identifies Body Mass Index and Fasting Insulin as Potential Causal Risk Factors for Pancreatic Cancer Risk.

J Natl Cancer Inst 2017 09;109(9)

Department of Hygiene and Epidemiology, School of Medicine, University of Ioannina, Ioannina, Greece; Department of Epidemiology and Biostatistics, The School of Public Health, Imperial College London, London, United Kingdom; Fred Hutchinson Cancer Research Center, Seattle, WA; Department of Epidemiology, University of Washington School of Public Health, Seattle, WA.

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http://dx.doi.org/10.1093/jnci/djx043DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6075551PMC
September 2017

Quantification of Multiple Tumor Clones Using Gene Array and Sequencing Data.

Ann Appl Stat 2017 Jun 20;11(2):967-991. Epub 2017 Jul 20.

Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.

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http://dx.doi.org/10.1214/17-AOAS1026DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5728449PMC
June 2017

TwoPhaseInd: an R package for estimating gene-treatment interactions and discovering predictive markers in randomized clinical trials.

Bioinformatics 2016 11 4;32(21):3348-3350. Epub 2016 Jul 4.

Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA Department of Biostatistics, University of Washington, Seattle, WA, USA.

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http://dx.doi.org/10.1093/bioinformatics/btw391DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5079471PMC
November 2016

Detectable Tenofovir Levels in Breast-Feeding Infants of Mothers Exposed to Topical Tenofovir.

Antimicrob Agents Chemother 2016 09 22;60(9):5616-9. Epub 2016 Aug 22.

Department of Obstetrics, Gynecology & Reproductive Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.

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http://dx.doi.org/10.1128/AAC.00645-16DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4997886PMC
September 2016

Constrained Score Statistics Identify Genetic Variants Interacting with Multiple Risk Factors in Barrett's Esophagus.

Am J Hum Genet 2016 08;99(2):352-65

Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA; Department of Epidemiology, University of Washington, Seattle, WA 98195, USA.

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http://dx.doi.org/10.1016/j.ajhg.2016.06.018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4974090PMC
August 2016

Group association test using a hidden Markov model.

Biostatistics 2016 Apr 28;17(2):221-34. Epub 2015 Sep 28.

Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.

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http://dx.doi.org/10.1093/biostatistics/kxv035DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4834946PMC
April 2016

Augmented case-only designs for randomized clinical trials with failure time endpoints.

Biometrics 2016 Mar 8;72(1):30-8. Epub 2015 Sep 8.

Fred Hutchinson Cancer Research Center and University of Washington, Seattle, Washington.

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http://dx.doi.org/10.1111/biom.12392DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4808468PMC
March 2016

Bone Mineral Density Changes Among Young, Healthy African Women Receiving Oral Tenofovir for HIV Preexposure Prophylaxis.

J Acquir Immune Defic Syndr 2016 Mar;71(3):287-94

*Makerere University-Johns Hopkins University Research Collaboration, Kampala, Uganda; †Statistical Center for HIV/AIDS Research & Prevention (SCHARP)-Fred Hutchinson Cancer Research Center, Seattle, WA; ‡Department of Obstetrics and Gynaecology, University of Zimbabwe-University of California San Francisco, Harare, Zimbabwe; §Department of Medicine, University of Pittsburgh, Pittsburgh, PA; ‖FHI 360, Durham, NC; ¶Division of AIDS/National Institute of Allergy and Infectious Diseases/National Institutes of Health, Bethesda, MD; and #Department of medicine and Global Health, University of Washington, Seattle, WA.

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http://dx.doi.org/10.1097/QAI.0000000000000858DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4755358PMC
March 2016

Pharmacological Measures of Treatment Adherence and Risk of HIV Infection in the VOICE Study.

J Infect Dis 2016 Feb 29;213(3):335-42. Epub 2015 Jun 29.

Vaccine and Infectious Diseases Division, Fred Hutchinson Cancer Research Center University of Washington, Seattle.

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http://dx.doi.org/10.1093/infdis/jiv333DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4704663PMC
February 2016

A newly identified susceptibility locus near FOXP1 modifies the association of gastroesophageal reflux with Barrett's esophagus.

Cancer Epidemiol Biomarkers Prev 2015 Nov 16;24(11):1739-47. Epub 2015 Sep 16.

Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington. Department of Epidemiology, University of Washington, School of Public Health, Seattle, Washington.

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http://dx.doi.org/10.1158/1055-9965.EPI-15-0507DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4816532PMC
November 2015

Factors associated with bone mineral density in healthy African women.

Arch Osteoporos 2015 14;10:206. Epub 2015 Feb 14.

University of Zimbabwe-University of California San Francisco Collaborative Research Programme, 15 Phillips Avenue, Belgravia, Harare, Zimbabwe,

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http://dx.doi.org/10.1007/s11657-015-0206-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4564062PMC
September 2015

Copy number alterations detected by whole-exome and whole-genome sequencing of esophageal adenocarcinoma.

Hum Genomics 2015 Sep 15;9:22. Epub 2015 Sep 15.

Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.

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http://dx.doi.org/10.1186/s40246-015-0044-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4570720PMC
September 2015

Tenofovir-based preexposure prophylaxis for HIV infection among African women.

N Engl J Med 2015 Feb;372(6):509-18

From the University of Washington (J.M.M.) and the Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center (B.A.R., J.Y.D., B. Mâsse) - both in Seattle; the HIV Prevention Research Unit, Medical Research Council (G.R., S.G.), and the Centre for AIDS Programme of Research in South Africa (CAPRISA), Durban (G.N.), Witwatersrand Reproductive Health and HIV Research Institute (T.P.) and Perinatal HIV Research Unit (B. Mkhize), Johannesburg, and the AURUM Institute, Klerksdorp (M.T.) - all in South Africa; FHI 360, Durham, NC (K.G.); University of Zimbabwe-University of California San Francisco Research Programme, Harare, Zimbabwe (N.M., Z.M.C.); Makerere University-Johns Hopkins University Research Collaboration, Kampala, Uganda (C.N.); Women's Global Health Imperative, Research Triangle Institute (RTI) International, San Francisco (A.S.); Magee-Womens Research Institute, University of Pittsburgh Medical Center, Pittsburgh (L.N., U.M.P., S.L.H., I.M.M.); Johns Hopkins University School of Medicine, Baltimore (C.W.H., M.A.M.); Division of AIDS, National Institute of Allergy and Infectious Diseases (J.P.), National Institutes of Mental Health (C.G.), and the Eunice Shriver Kennedy National Institute of Child Health and Human Development (H.W.), National Institutes of Health - all in Bethesda, MD; Gilead Sciences, Foster City, CA (J.R.); CONRAD, Arlington, VA (J.L.S.); and Centre Hospitalier Universitaire Sainte-Justine, University of Montreal, Montreal (B. Mâsse).

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http://dx.doi.org/10.1056/NEJMoa1402269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4341965PMC
February 2015

Testing concordance of instrumental variable effects in generalized linear models with application to Mendelian randomization.

Stat Med 2014 Oct 26;33(23):3986-4007. Epub 2014 May 26.

John Wiley & Sons, Ltd, The Atrium, Southern Gate, Chichester, West Sussex, PO19 8SQ, U.K.

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http://dx.doi.org/10.1002/sim.6217DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4309290PMC
October 2014

Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data.

Authors:
Michael V Holmes Caroline E Dale Luisa Zuccolo Richard J Silverwood Yiran Guo Zheng Ye David Prieto-Merino Abbas Dehghan Stella Trompet Andrew Wong Alana Cavadino Dagmar Drogan Sandosh Padmanabhan Shanshan Li Ajay Yesupriya Maarten Leusink Johan Sundstrom Jaroslav A Hubacek Hynek Pikhart Daniel I Swerdlow Andrie G Panayiotou Svetlana A Borinskaya Chris Finan Sonia Shah Karoline B Kuchenbaecker Tina Shah Jorgen Engmann Lasse Folkersen Per Eriksson Fulvio Ricceri Olle Melander Carlotta Sacerdote Dale M Gamble Sruti Rayaprolu Owen A Ross Stela McLachlan Olga Vikhireva Ivonne Sluijs Robert A Scott Vera Adamkova Leon Flicker Frank M van Bockxmeer Christine Power Pedro Marques-Vidal Tom Meade Michael G Marmot Jose M Ferro Sofia Paulos-Pinheiro Steve E Humphries Philippa J Talmud Irene Mateo Leach Niek Verweij Allan Linneberg Tea Skaaby Pieter A Doevendans Maarten J Cramer Pim van der Harst Olaf H Klungel Nicole F Dowling Anna F Dominiczak Meena Kumari Andrew N Nicolaides Cornelia Weikert Heiner Boeing Shah Ebrahim Tom R Gaunt Jackie F Price Lars Lannfelt Anne Peasey Ruzena Kubinova Andrzej Pajak Sofia Malyutina Mikhail I Voevoda Abdonas Tamosiunas Anke H Maitland-van der Zee Paul E Norman Graeme J Hankey Manuela M Bergmann Albert Hofman Oscar H Franco Jackie Cooper Jutta Palmen Wilko Spiering Pim A de Jong Diana Kuh Rebecca Hardy Andre G Uitterlinden M Arfan Ikram Ian Ford Elina Hyppönen Osvaldo P Almeida Nicholas J Wareham Kay-Tee Khaw Anders Hamsten Lise Lotte N Husemoen Anne Tjønneland Janne S Tolstrup Eric Rimm Joline W J Beulens W M Monique Verschuren N Charlotte Onland-Moret Marten H Hofker S Goya Wannamethee Peter H Whincup Richard Morris Astrid M Vicente Hugh Watkins Martin Farrall J Wouter Jukema James Meschia L Adrienne Cupples Stephen J Sharp Myriam Fornage Charles Kooperberg Andrea Z LaCroix James Y Dai Matthew B Lanktree David S Siscovick Eric Jorgenson Bonnie Spring Josef Coresh Yun R Li Sarah G Buxbaum Pamela J Schreiner R Curtis Ellison Michael Y Tsai Sanjay R Patel Susan Redline Andrew D Johnson Ron C Hoogeveen Hakon Hakonarson Jerome I Rotter Eric Boerwinkle Paul I W de Bakker Mika Kivimaki Folkert W Asselbergs Naveed Sattar Debbie A Lawlor John Whittaker George Davey Smith Kenneth Mukamal Bruce M Psaty James G Wilson Leslie A Lange Ajna Hamidovic Aroon D Hingorani Børge G Nordestgaard Martin Bobak David A Leon Claudia Langenberg Tom M Palmer Alex P Reiner Brendan J Keating Frank Dudbridge Juan P Casas

BMJ 2014 Jul 10;349:g4164. Epub 2014 Jul 10.

Genetic Epidemiology Group, Institute of Cardiovascular Science, Department of Epidemiology and Public Health, University College London, UK Faculty of Epidemiology and Population Health, London School of Hygiene & Tropical Medicine, London, WC1E 7HT, UK

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4091648PMC
http://dx.doi.org/10.1136/bmj.g4164DOI Listing
July 2014

Case-only method for cause-specific hazards models with application to assessing differential vaccine efficacy by viral and host genetics.

Biostatistics 2014 Jan 27;15(1):196-203. Epub 2013 Jun 27.

Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.

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http://dx.doi.org/10.1093/biostatistics/kxt018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3862206PMC
January 2014

Immunoglobulin genes and the acquisition of HIV infection in a randomized trial of recombinant adenovirus HIV vaccine.

Virology 2013 Jun 11;441(1):70-4. Epub 2013 Apr 11.

Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC, USA.

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http://dx.doi.org/10.1016/j.virol.2013.03.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750738PMC
June 2013

Immunoglobulin genes and the acquisition of HIV infection in a randomized trial of recombinant adenovirus HIV vaccine.

Virology 2013 Jun 11;441(1):70-4. Epub 2013 Apr 11.

Department of Microbiology and Immunology, Medical University of South Carolina, Charleston, SC, USA.

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http://dx.doi.org/10.1016/j.virol.2013.03.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3750738PMC
June 2013

Estimating the efficacy of preexposure prophylaxis for HIV prevention among participants with a threshold level of drug concentration.

Am J Epidemiol 2013 Feb 9;177(3):256-63. Epub 2013 Jan 9.

Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.

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http://dx.doi.org/10.1093/aje/kws324DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3577049PMC
February 2013

Two-stage testing procedures with independent filtering for genome-wide gene-environment interaction.

Biometrika 2012 Dec 25;99(4):929-944. Epub 2012 Sep 25.

Public Health Science Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, U.S.A. ,

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http://dx.doi.org/10.1093/biomet/ass044DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3629859PMC
December 2012

A unified procedure for meta-analytic evaluation of surrogate end points in randomized clinical trials.

Biostatistics 2012 Sep 6;13(4):609-24. Epub 2012 Mar 6.

Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.

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http://dx.doi.org/10.1093/biostatistics/kxs003DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3616754PMC
September 2012

A novel variational Bayes multiple locus Z-statistic for genome-wide association studies with Bayesian model averaging.

Bioinformatics 2012 Jul 4;28(13):1738-44. Epub 2012 May 4.

Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 98109, Seattle, WA 98195, USA.

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http://dx.doi.org/10.1093/bioinformatics/bts261DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3381972PMC
July 2012

Simultaneously testing for marginal genetic association and gene-environment interaction.

Am J Epidemiol 2012 Jul 6;176(2):164-73. Epub 2012 Jul 6.

Public Health Science Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.

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http://dx.doi.org/10.1093/aje/kwr521DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499112PMC
July 2012

Powerful cocktail methods for detecting genome-wide gene-environment interaction.

Genet Epidemiol 2012 Apr;36(3):183-94

Biostatistics and Biomathematics Program, Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.

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http://dx.doi.org/10.1002/gepi.21610DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3654520PMC
April 2012

Partially hidden Markov model for time-varying principal stratification in HIV prevention trials.

J Am Stat Assoc 2012 Mar;107(497):52-65

Vaccine and Infectious Disease Institute Fred Hutchinson Cancer Research Center, Seattle, WA 98109

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http://dx.doi.org/10.1080/01621459.2011.643743DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3649016PMC
March 2012

Genetic variants in the MRPS30 region and postmenopausal breast cancer risk.

Genome Med 2012 Mar 12;4(3):19. Epub 2012 Mar 12.

Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue N, M3-A410, POB 19024, Seattle, WA 98109-1024, USA.

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http://dx.doi.org/10.1186/gm318DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446269PMC
March 2012

Connections between survey calibration estimators and semiparametric models for incomplete data.

Int Stat Rev 2011 Aug;79(2):200-220

Department of Biostatistics, University of Washington, Seattle, WA ; Fred Hutchinson Cancer Research Center, Seattle, WA.

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http://doi.wiley.com/10.1111/j.1751-5823.2011.00138.x
Publisher Site
http://dx.doi.org/10.1111/j.1751-5823.2011.00138.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3699889PMC
August 2011

Genetic variants in the MRPS30 region and postmenopausal breast cancer risk.

Genome Med 2011 Jun 24;3(6):42. Epub 2011 Jun 24.

Fred Hutchinson Cancer Research Center, Divisions of Public Health Sciences, and Vaccine and Infectious Diseases, 1100 Fairview Avenue North, Seattle, WA 98109-1024, USA.

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http://dx.doi.org/10.1186/gm258DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218816PMC
June 2011

SHARE: an adaptive algorithm to select the most informative set of SNPs for candidate genetic association.

Biostatistics 2009 Oct 15;10(4):680-93. Epub 2009 Jul 15.

Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue N, M2-C200, Seattle, WA 98109, USA.

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https://academic.oup.com/biostatistics/article-lookup/doi/10
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http://dx.doi.org/10.1093/biostatistics/kxp023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2742496PMC
October 2009

The Met protooncogene is a transcriptional target of NF kappaB: implications for cell survival.

J Cell Biochem 2009 Aug;107(6):1222-36

Department of Pathology, University of Pittsburgh, Pittsburgh, Pennsylvania 15261, USA.

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http://dx.doi.org/10.1002/jcb.22226DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2868332PMC
August 2009

Semiparametric estimation exploiting covariate independence in two-phase randomized trials.

Biometrics 2009 Mar 13;65(1):178-87. Epub 2008 May 13.

Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.

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http://dx.doi.org/10.1111/j.1541-0420.2008.01046.xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2892338PMC
March 2009

Structures and Assumptions: Strategies to Harness Gene × Gene and Gene × Environment Interactions in GWAS.

Stat Sci 2009 ;24(4):472-488

Fred Hutchinson Cancer Research Center Division of Public Health Sciences.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2904990PMC
January 2009

The optimal discovery procedure for large-scale significance testing, with applications to comparative microarray experiments.

Biostatistics 2007 Apr 23;8(2):414-32. Epub 2006 Aug 23.

Department of Biostatistics, University of Washington, Seattle, WA 98195, USA.

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https://academic.oup.com/biostatistics/article-lookup/doi/10
Publisher Site
http://dx.doi.org/10.1093/biostatistics/kxl019DOI Listing
April 2007

Imputation methods to improve inference in SNP association studies.

Genet Epidemiol 2006 Dec;30(8):690-702

Department of Biostatistics, University of Washington, Seattle, Washington, USA.

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http://dx.doi.org/10.1002/gepi.20180DOI Listing
December 2006