James Wason

James Wason

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James Wason

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A latent variable model for improving inference in trials assessing the effect of dose on toxicity and composite efficacy endpoints.

Stat Methods Med Res 2020 Jan 25;29(1):230-242. Epub 2019 Feb 25.

MRC Biostatistics Unit, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1177/0962280219831038DOI Listing
January 2020

Effect of sleep deprivation and exercise on reaction threshold in adults with peanut allergy: A randomized controlled study.

J Allergy Clin Immunol 2019 Dec 15;144(6):1584-1594.e2. Epub 2019 Jul 15.

Department of Medicine, University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom; Department of Allergy, Addenbrooke's Hospital, Cambridge, United Kingdom.

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http://dx.doi.org/10.1016/j.jaci.2019.06.038DOI Listing
December 2019

Overestimated treatment effects in randomised phase II trials: What's up doctor?

Eur J Cancer 2019 Dec 1;123:116-117. Epub 2019 Nov 1.

Institute of Health and Society, Newcastle University, Newcastle Upon Tyne, UK; MRC Biostatistics Unit, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1016/j.ejca.2019.09.023DOI Listing
December 2019

Evaluation of PR3-ANCA Status After Rituximab for ANCA-Associated Vasculitis.

J Clin Rheumatol 2019 Aug;25(5):217-223

From the Vasculitis and Lupus Clinic, Addenbrooke's Hospital, Cambridge University Hospitals.

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http://dx.doi.org/10.1097/RHU.0000000000001030DOI Listing
August 2019

To add or not to add a new treatment arm to a multiarm study: A decision-theoretic framework.

Stat Med 2019 Aug 21;38(18):3305-3321. Epub 2019 May 21.

WMS - Statistics and Epidemiology, University of Warwick, Coventry, UK.

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https://onlinelibrary.wiley.com/doi/abs/10.1002/sim.8194
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http://dx.doi.org/10.1002/sim.8194DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6619445PMC
August 2019

When to keep it simple - adaptive designs are not always useful.

BMC Med 2019 08 2;17(1):152. Epub 2019 Aug 2.

Cancer Research UK Clinical Trials Unit, University of Birmingham, Birmingham, UK.

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http://dx.doi.org/10.1186/s12916-019-1391-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6676635PMC
August 2019

Anti-VEGF intervention in neovascular AMD: benefits and risks restated as natural frequencies.

BMJ Open Ophthalmol 2019 14;4(1):e000257. Epub 2019 Jun 14.

Eye, Wirral University Teaching Hospital NHS Foundation Trust, Wirral, UK.

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http://dx.doi.org/10.1136/bmjophth-2018-000257DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579561PMC
June 2019

Admissible multiarm stepped-wedge cluster randomized trial designs.

Stat Med 2019 Mar 6;38(7):1103-1119. Epub 2018 Nov 6.

Hub for Trials Methodology Research, MRC Biostatistics Unit, University of Cambridge, Cambridge, UK.

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http://doi.wiley.com/10.1002/sim.8022
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http://dx.doi.org/10.1002/sim.8022DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6491976PMC
March 2019

Design of experiments for a confirmatory trial of precision medicine.

J Stat Plan Inference 2019 Mar;199:179-187

MRC Biostatistics Unit, School of Clinical Medicine, University of Cambridge, UK.

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http://dx.doi.org/10.1016/j.jspi.2018.06.004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6473552PMC
March 2019

Multi-arm multi-stage trials can improve the efficiency of finding effective treatments for stroke: a case study.

BMC Cardiovasc Disord 2018 11 27;18(1):215. Epub 2018 Nov 27.

MRC Biostatistics Unit, Cambridge, UK.

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http://dx.doi.org/10.1186/s12872-018-0956-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6260683PMC
November 2018

Group sequential crossover trial designs with strong control of the familywise error rate.

Seq Anal 2018 2;37(2):174-203. Epub 2018 Oct 2.

Hub for Trials Methodology Research, MRC Biostatistics Unit, Cambridge, UK.

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https://www.tandfonline.com/doi/full/10.1080/07474946.2018.1
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http://dx.doi.org/10.1080/07474946.2018.1466528DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6199128PMC
October 2018

Blinded and unblinded sample size reestimation in crossover trials balanced for period.

Biom J 2018 09 3;60(5):917-933. Epub 2018 Aug 3.

MRC Biostatistics Unit, Cambridge Institute of Public Health, Forvie Site, Robinson Way, Cambridge, UK.

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http://dx.doi.org/10.1002/bimj.201700092DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175184PMC
September 2018

Blinded and unblinded sample size reestimation procedures for stepped-wedge cluster randomized trials.

Biom J 2018 09 3;60(5):903-916. Epub 2018 Aug 3.

MRC Biostatistics Unit, Cambridge Institute of Public Health, Forvie Site, Robinson Way, Cambridge Biomedical Campus, Cambridge, UK.

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http://dx.doi.org/10.1002/bimj.201700125DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6175439PMC
September 2018

Improving the analysis of composite endpoints in rare disease trials.

Orphanet J Rare Dis 2018 05 22;13(1):81. Epub 2018 May 22.

MRC Biostatistics Unit, University of Cambridge, Forvie Site, Cambridge, UK.

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http://dx.doi.org/10.1186/s13023-018-0819-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5964664PMC
May 2018

An optimised multi-arm multi-stage clinical trial design for unknown variance.

Contemp Clin Trials 2018 04 21;67:116-120. Epub 2018 Feb 21.

Hub for Trials Methodology Research, MRC Biostatistics Unit, Cambridge, UK.

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http://dx.doi.org/10.1016/j.cct.2018.02.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5886309PMC
April 2018

Response-adaptive designs for binary responses: How to offer patient benefit while being robust to time trends?

Pharm Stat 2018 03 19;17(2):182-197. Epub 2017 Dec 19.

MRC Biostatistics Unit, Cambridge Institute of Public Health, Cambridge, UK.

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http://doi.wiley.com/10.1002/pst.1845
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http://dx.doi.org/10.1002/pst.1845DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5877788PMC
March 2018

The longitudinal effect of ejaculation on seminal vesicle fluid volume and whole-prostate ADC as measured on prostate MRI.

Eur Radiol 2017 Dec 4;27(12):5236-5243. Epub 2017 Jul 4.

Department of Radiology, Addenbrooke's Hospital and University of Cambridge, Cambridge, CB2 0QQ, UK.

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http://dx.doi.org/10.1007/s00330-017-4905-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5674119PMC
December 2017

Improving phase II oncology trials using best observed RECIST response as an endpoint by modelling continuous tumour measurements.

Stat Med 2017 Dec 28;36(29):4616-4626. Epub 2017 Aug 28.

MRC Biostatistics Unit, University of Cambridge, U.K.

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http://dx.doi.org/10.1002/sim.7453DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5724692PMC
December 2017

Group sequential designs for stepped-wedge cluster randomised trials.

Clin Trials 2017 Oct 27;14(5):507-517. Epub 2017 Jun 27.

MRC Biostatistics Unit Hub for Trials Methodology Research, Cambridge Institute of Public Health, Cambridge, UK.

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http://dx.doi.org/10.1177/1740774517716937DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5632563PMC
October 2017

Two-stage phase II oncology designs using short-term endpoints for early stopping.

Stat Methods Med Res 2017 Aug 2;26(4):1671-1683. Epub 2015 Jun 2.

3 Institute of Medical Biometry and Informatics, University of Heidelberg, Germany.

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http://dx.doi.org/10.1177/0962280215585819DOI Listing
August 2017

Imaging biomarker roadmap for cancer studies.

Nat Rev Clin Oncol 2017 03 11;14(3):169-186. Epub 2016 Oct 11.

CRUK and EPSRC Cancer Imaging Centre in Cambridge and Manchester, University of Manchester, Manchester, UK.

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http://dx.doi.org/10.1038/nrclinonc.2016.162DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378302PMC
March 2017

A multi-stage drop-the-losers design for multi-arm clinical trials.

Stat Methods Med Res 2017 Feb 30;26(1):508-524. Epub 2016 Sep 30.

3 Department of Mathematical Sciences, University of Bath, Bath, UK.

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http://dx.doi.org/10.1177/0962280214550759DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5302074PMC
February 2017

Stepped wedge cluster randomized controlled trial designs: a review of reporting quality and design features.

Trials 2017 01 21;18(1):33. Epub 2017 Jan 21.

MRC Biostatistics Unit Hub for Trials Methodology Research, Cambridge Institute of Public Health, University Forvie Site, Robinson Way, Cambridge, CB2 0SR, UK.

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http://dx.doi.org/10.1186/s13063-017-1783-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5251280PMC
January 2017

An adaptive design for updating the threshold value of a continuous biomarker.

Stat Med 2016 11 14;35(27):4909-4923. Epub 2016 Jul 14.

AstraZeneca, Global Medicines Development, Biometrics and Information Sciences, Mereside, Alderley Park, Macclesfield, SK10 4TG, U.K.

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http://dx.doi.org/10.1002/sim.7042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5378309PMC
November 2016

Improving the power of clinical trials of rheumatoid arthritis by using data on continuous scales when analysing response rates: an application of the augmented binary method.

Rheumatology (Oxford) 2016 10 23;55(10):1796-802. Epub 2016 Jun 23.

Global Medicines Development, AstraZeneca Pharmaceuticals, Cambridge, UK.

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http://dx.doi.org/10.1093/rheumatology/kew263DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5034221PMC
October 2016

Use of an embedded, micro-randomised trial to investigate non-compliance in telehealth interventions.

Clin Trials 2016 08 11;13(4):417-24. Epub 2016 Mar 11.

MRC Biostatistics Unit Hub for Trials Methodology Research, Cambridge, UK.

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http://dx.doi.org/10.1177/1740774516637075DOI Listing
August 2016

Endoplasmic reticulum stress, unfolded protein response and development of colon adenocarcinoma.

Virchows Arch 2016 Aug 25;469(2):145-54. Epub 2016 May 25.

Department of Pathology, Rouen University Hospital, Rouen, France.

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http://dx.doi.org/10.1007/s00428-016-1961-6DOI Listing
August 2016

A review of statistical designs for improving the efficiency of phase II studies in oncology.

Stat Methods Med Res 2016 06 31;25(3):1010-21. Epub 2015 May 31.

Department of Mathematics and Statistics, Lancaster University, Lancaster, UK

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http://dx.doi.org/10.1177/0962280215588247DOI Listing
June 2016

Some recommendations for multi-arm multi-stage trials.

Stat Methods Med Res 2016 04 12;25(2):716-27. Epub 2012 Dec 12.

Medical and Pharmaceutical Statistics Research Unit, Department of Mathematics and Statistics, Lancaster University, UK.

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http://dx.doi.org/10.1177/0962280212465498DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4843088PMC
April 2016

HLA associations in South Asian multiple sclerosis.

Mult Scler 2016 Jan 28;22(1):19-24. Epub 2015 Apr 28.

Center for Advanced Neurological Research, KS Hegde Medical College, Nitte University, Mangalore, Karnataka, India.

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http://dx.doi.org/10.1177/1352458515581439DOI Listing
January 2016

The choice of test in phase II cancer trials assessing continuous tumour shrinkage when complete responses are expected.

Stat Methods Med Res 2015 Dec 16;24(6):909-19. Epub 2011 Dec 16.

Hub for Trials Methodology Research, MRC Biostatistics Unit, Cambridge, UK.

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http://dx.doi.org/10.1177/0962280211432192DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4668774PMC
December 2015

Response-adaptive randomization for multi-arm clinical trials using the forward looking Gittins index rule.

Biometrics 2015 Dec 22;71(4):969-78. Epub 2015 Jun 22.

MRC Biostatistics Unit, Institute of Public Health, University Forvie Site, Robinson Way, Cambridge CB2 0SR, U.K.

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http://dx.doi.org/10.1111/biom.12337DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856210PMC
December 2015

A Bayesian adaptive design for biomarker trials with linked treatments.

Br J Cancer 2015 Sep 11;113(5):699-705. Epub 2015 Aug 11.

MRC Biostatistics Unit Hub for Trials Methodology Research, Cambridge, UK.

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http://dx.doi.org/10.1038/bjc.2015.278DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4559835PMC
September 2015

Multi-armed Bandit Models for the Optimal Design of Clinical Trials: Benefits and Challenges.

Stat Sci 2015;30(2):199-215

Senior Investigator Statistician at MRC BSU, Cambridge, MRC Biostatistics Unit, Cambridge Institute of Public Health, Forvie Site, Robinson Way, Cambridge Biomedical Campus, Cambridge CB2 0SR, United Kingdom.

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http://dx.doi.org/10.1214/14-STS504DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4856206PMC
January 2015

Design of telehealth trials--introducing adaptive approaches.

Int J Med Inform 2014 Dec 16;83(12):870-80. Epub 2014 Sep 16.

MRC Biostatistics Unit, Institute of Public Health, Forvie site, Robinson Way, Cambridge CB2 0SR, United Kingdom.

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http://dx.doi.org/10.1016/j.ijmedinf.2014.09.002DOI Listing
December 2014

Confounding in association studies: month of birth and multiple sclerosis.

J Neurol 2014 Oct 12;261(10):1851-6. Epub 2014 Jan 12.

Department of Clinical Neurosciences, University of Cambridge, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0QQ, UK.

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http://dx.doi.org/10.1007/s00415-014-7241-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4192561PMC
October 2014

Correcting for multiple-testing in multi-arm trials: is it necessary and is it done?

Trials 2014 Sep 17;15:364. Epub 2014 Sep 17.

MRC Biostatistics Unit Hub for Trials Methodology Research, Institute of Public Health, Robinson Way, Cambridge CB2 0SR, UK.

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http://trialsjournal.biomedcentral.com/articles/10.1186/1745
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http://dx.doi.org/10.1186/1745-6215-15-364DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4177585PMC
September 2014

A comparison of Bayesian adaptive randomization and multi-stage designs for multi-arm clinical trials.

Stat Med 2014 Jun 14;33(13):2206-21. Epub 2014 Jan 14.

MRC Biostatistics Unit, Institute of Public Health, Cambridge, U.K.

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http://dx.doi.org/10.1002/sim.6086DOI Listing
June 2014

Comment on: Month of birth and risk of multiple sclerosis: confounding and adjustments.

Ann Clin Transl Neurol 2014 May 10;1(5):375. Epub 2014 Apr 10.

Department of Clinical Neurosciences, University of Cambridge Box 165, Cambridge Biomedical Campus, Hills Road, Cambridge, CB2 0QQ, United Kingdom.

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http://dx.doi.org/10.1002/acn3.53DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4184689PMC
May 2014

Using continuous data on tumour measurements to improve inference in phase II cancer studies.

Stat Med 2013 Nov 18;32(26):4639-50. Epub 2013 Jun 18.

MRC Biostatistics Unit, Cambridge, U.K.

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http://dx.doi.org/10.1002/sim.5867DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4282550PMC
November 2013

Planning multi-arm screening studies within the context of a drug development program.

Stat Med 2013 Sep 26;32(20):3424-35. Epub 2013 Mar 26.

Hub for Trials Methodology Research, MRC Biostatistics Unit, Cambridge, U.K.

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http://doi.wiley.com/10.1002/sim.5787
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http://dx.doi.org/10.1002/sim.5787DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3882502PMC
September 2013

Confounding underlies the apparent month of birth effect in multiple sclerosis.

Ann Neurol 2013 Jun 2;73(6):714-20. Epub 2013 Jul 2.

University of Cambridge, Department of Clinical Neurosciences, Addenbrooke's Hospital, Cambridge, United Kingdom.

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http://dx.doi.org/10.1002/ana.23925DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3748787PMC
June 2013

Identifying combined design and analysis procedures in two-stage trials with a binary end point.

Stat Med 2012 Dec 11;31(29):3874-84. Epub 2012 Jul 11.

MRC Biostatistics Unit, Cambridge, UK.

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http://dx.doi.org/10.1002/sim.5468DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3546375PMC
December 2012

Optimal design of multi-arm multi-stage trials.

Stat Med 2012 Dec 23;31(30):4269-79. Epub 2012 Jul 23.

Hub for Trials Methodology Research, MRC Biostatistics Unit, Cambridge, UK.

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http://dx.doi.org/10.1002/sim.5513DOI Listing
December 2012

Risk in complex genetics: "all models are wrong but some are useful".

Ann Neurol 2012 Oct 18;72(4):502-9. Epub 2012 May 18.

Department of Clinical Neuroscience, Addenbrooke's Hospital, University of Cambridge, Cambridge, UK.

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http://dx.doi.org/10.1002/ana.23613DOI Listing
October 2012

Minimizing the maximum expected sample size in two-stage Phase II clinical trials with continuous outcomes.

J Biopharm Stat 2012 ;22(4):836-52

MRC Biostatistics Unit Hub for Trials Methodology Research, Cambridge, United Kingdom.

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http://www.tandfonline.com/doi/abs/10.1080/10543406.2010.528
Publisher Site
http://dx.doi.org/10.1080/10543406.2010.528104DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3662082PMC
October 2012

Admissible two-stage designs for phase II cancer clinical trials that incorporate the expected sample size under the alternative hypothesis.

Pharm Stat 2012 Mar-Apr;11(2):91-6. Epub 2012 Jan 10.

MRC Biostatistics Unit Hub in Trials Methodology Research, Institute of Public Health, University Forvie Site, Cambridge CB2 0SR, UK.

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http://doi.wiley.com/10.1002/pst.501
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http://dx.doi.org/10.1002/pst.501DOI Listing
July 2012

A general framework for two-stage analysis of genome-wide association studies and its application to case-control studies.

Am J Hum Genet 2012 May;90(5):760-73

Medical Research Council Biostatistics Unit, Institute for Public Health, Cambridge, UK.

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http://dx.doi.org/10.1016/j.ajhg.2012.03.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3376500PMC
May 2012

Optimal multistage designs for randomised clinical trials with continuous outcomes.

Stat Med 2012 Feb 5;31(4):301-12. Epub 2011 Dec 5.

Hub for Trials Methodology Research, MRC Biostatistics Unit, Cambridge, UK.

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http://dx.doi.org/10.1002/sim.4421DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3499690PMC
February 2012

Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis.

Authors:
Stephen Sawcer Garrett Hellenthal Matti Pirinen Chris C A Spencer Nikolaos A Patsopoulos Loukas Moutsianas Alexander Dilthey Zhan Su Colin Freeman Sarah E Hunt Sarah Edkins Emma Gray David R Booth Simon C Potter An Goris Gavin Band Annette Bang Oturai Amy Strange Janna Saarela Céline Bellenguez Bertrand Fontaine Matthew Gillman Bernhard Hemmer Rhian Gwilliam Frauke Zipp Alagurevathi Jayakumar Roland Martin Stephen Leslie Stanley Hawkins Eleni Giannoulatou Sandra D'alfonso Hannah Blackburn Filippo Martinelli Boneschi Jennifer Liddle Hanne F Harbo Marc L Perez Anne Spurkland Matthew J Waller Marcin P Mycko Michelle Ricketts Manuel Comabella Naomi Hammond Ingrid Kockum Owen T McCann Maria Ban Pamela Whittaker Anu Kemppinen Paul Weston Clive Hawkins Sara Widaa John Zajicek Serge Dronov Neil Robertson Suzannah J Bumpstead Lisa F Barcellos Rathi Ravindrarajah Roby Abraham Lars Alfredsson Kristin Ardlie Cristin Aubin Amie Baker Katharine Baker Sergio E Baranzini Laura Bergamaschi Roberto Bergamaschi Allan Bernstein Achim Berthele Mike Boggild Jonathan P Bradfield David Brassat Simon A Broadley Dorothea Buck Helmut Butzkueven Ruggero Capra William M Carroll Paola Cavalla Elisabeth G Celius Sabine Cepok Rosetta Chiavacci Françoise Clerget-Darpoux Katleen Clysters Giancarlo Comi Mark Cossburn Isabelle Cournu-Rebeix Mathew B Cox Wendy Cozen Bruce A C Cree Anne H Cross Daniele Cusi Mark J Daly Emma Davis Paul I W de Bakker Marc Debouverie Marie Beatrice D'hooghe Katherine Dixon Rita Dobosi Bénédicte Dubois David Ellinghaus Irina Elovaara Federica Esposito Claire Fontenille Simon Foote Andre Franke Daniela Galimberti Angelo Ghezzi Joseph Glessner Refujia Gomez Olivier Gout Colin Graham Struan F A Grant Franca Rosa Guerini Hakon Hakonarson Per Hall Anders Hamsten Hans-Peter Hartung Rob N Heard Simon Heath Jeremy Hobart Muna Hoshi Carmen Infante-Duarte Gillian Ingram Wendy Ingram Talat Islam Maja Jagodic Michael Kabesch Allan G Kermode Trevor J Kilpatrick Cecilia Kim Norman Klopp Keijo Koivisto Malin Larsson Mark Lathrop Jeannette S Lechner-Scott Maurizio A Leone Virpi Leppä Ulrika Liljedahl Izaura Lima Bomfim Robin R Lincoln Jenny Link Jianjun Liu Aslaug R Lorentzen Sara Lupoli Fabio Macciardi Thomas Mack Mark Marriott Vittorio Martinelli Deborah Mason Jacob L McCauley Frank Mentch Inger-Lise Mero Tania Mihalova Xavier Montalban John Mottershead Kjell-Morten Myhr Paola Naldi William Ollier Alison Page Aarno Palotie Jean Pelletier Laura Piccio Trevor Pickersgill Fredrik Piehl Susan Pobywajlo Hong L Quach Patricia P Ramsay Mauri Reunanen Richard Reynolds John D Rioux Mariaemma Rodegher Sabine Roesner Justin P Rubio Ina-Maria Rückert Marco Salvetti Erika Salvi Adam Santaniello Catherine A Schaefer Stefan Schreiber Christian Schulze Rodney J Scott Finn Sellebjerg Krzysztof W Selmaj David Sexton Ling Shen Brigid Simms-Acuna Sheila Skidmore Patrick M A Sleiman Cathrine Smestad Per Soelberg Sørensen Helle Bach Søndergaard Jim Stankovich Richard C Strange Anna-Maija Sulonen Emilie Sundqvist Ann-Christine Syvänen Francesca Taddeo Bruce Taylor Jenefer M Blackwell Pentti Tienari Elvira Bramon Ayman Tourbah Matthew A Brown Ewa Tronczynska Juan P Casas Niall Tubridy Aiden Corvin Jane Vickery Janusz Jankowski Pablo Villoslada Hugh S Markus Kai Wang Christopher G Mathew James Wason Colin N A Palmer H-Erich Wichmann Robert Plomin Ernest Willoughby Anna Rautanen Juliane Winkelmann Michael Wittig Richard C Trembath Jacqueline Yaouanq Ananth C Viswanathan Haitao Zhang Nicholas W Wood Rebecca Zuvich Panos Deloukas Cordelia Langford Audrey Duncanson Jorge R Oksenberg Margaret A Pericak-Vance Jonathan L Haines Tomas Olsson Jan Hillert Adrian J Ivinson Philip L De Jager Leena Peltonen Graeme J Stewart David A Hafler Stephen L Hauser Gil McVean Peter Donnelly Alastair Compston

Nature 2011 Aug 10;476(7359):214-9. Epub 2011 Aug 10.

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http://dx.doi.org/10.1038/nature10251DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3182531PMC
August 2011

Reducing sample sizes in two-stage phase II cancer trials by using continuous tumour shrinkage end-points.

Eur J Cancer 2011 May 14;47(7):983-9. Epub 2011 Jan 14.

MRC Biostatistics Unit, Hub for Trials Methodology Research, Cambridge, United Kingdom.

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https://linkinghub.elsevier.com/retrieve/pii/S09598049100118
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http://dx.doi.org/10.1016/j.ejca.2010.12.007DOI Listing
May 2011

What role for genetics in the prediction of multiple sclerosis?

Ann Neurol 2010 Jan;67(1):3-10

Department of Clinical Neurosciences, University of Cambridge, Addenbrooke's Hospital, Cambridge, UK.

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http://dx.doi.org/10.1002/ana.21911DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2830384PMC
January 2010